NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|397701909|gb|AFO59664|]
View 

interferon-induced protein with tetratricopeptide repeats 5, partial [Microcebus arnholdi]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-283 1.80e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.63  E-value: 1.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRARmiqikkatrnkpkgKDKLK 233
Cdd:COG2956   97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 397701909 234 vyelirsAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG2956  163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL 205
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-283 1.80e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.63  E-value: 1.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRARmiqikkatrnkpkgKDKLK 233
Cdd:COG2956   97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 397701909 234 vyelirsAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG2956  163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL 205
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 54-251 1.02e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 53.45  E-value: 1.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   54 ERPEIDCEKGWALLKFG--------GKYYQKAKAAFEKALEVEPDNPEFNIGYAIT-VYRLDDSDREGSvksfsLGPLRK 124
Cdd:TIGR00990 282 DSNELDEETGNGQLQLGlkspeskaDESYEEAARAFEKALDLGKLGEKEAIALNLRgTFKCLKGKHLEA-----LADLSK 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  125 AVTLNP--DNSYIKvfLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSF 202
Cdd:TIGR00990 357 SIELDPrvTQSYIK--RASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIF 434

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 397701909  203 LHHQMG-LCYR-----ARMIQIKKATRNKPKGKDKLKVYELIRSAIFHFKAAVEQ 251
Cdd:TIGR00990 435 SHIQLGvTQYKegsiaSSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEK 489
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 74-208 1.80e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAiTVYrLDDSDREGSVKSFslgplRKAVTLNPDNSYIKvFlaLKLQDVHAEAEGE 153
Cdd:cd24142   16 FELALKFLQRALELEPNNVEALELLG-EIL-LELGDVEEAREVL-----LRAIELDPDGGYEK-Y--LYLGQLSGGEEAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIE-------EILDQISFQPYVLRYAAKFYRRKHS---------W-----------DKALELLKKALEATPTSSFLHHQ 206
Cdd:cd24142   86 QYYEkgieileEELQALQAASAEAEEEAEELKRKLSsalcalaeiYmtdlcdepdaeQRCEELITKALELDPTNPEALQT 165


                 ..
gi 397701909 207 MG 208
Cdd:cd24142  166 LA 167
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-283 1.80e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.63  E-value: 1.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRARmiqikkatrnkpkgKDKLK 233
Cdd:COG2956   97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 397701909 234 vyelirsAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG2956  163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL 205
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 74-198 1.29e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG4783   20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDE-------AIVLLHEALELDPDEPEARLNLGLALLKAGDYDEAL 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATP 198
Cdd:COG4783   93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
62-283 1.15e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 1.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  62 KGWALLKFGgkYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDsdREGSVKSFslgplRKAVTLNPDNSYIKVFLAL 141
Cdd:COG0457   14 LGLAYRRLG--RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR--YEEALADY-----EQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 142 KLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYrARMIQIKKA 221
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL-EKLGRYEEA 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 397701909 222 TRNKPKGKDKLKVYELIRSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG0457  164 LELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLL 225
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 74-207 3.41e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 3.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG3914   94 YEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE-------ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQM 207
Cdd:COG3914  167 AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 74-203 1.48e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.74  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG2956  126 WEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDE-------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAI 198

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFL 203
Cdd:COG2956  199 AALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 76-201 4.10e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 4.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  76 KAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKY 155
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDE-------ALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEEL 73

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 397701909 156 IEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSS 201
Cdd:COG4235   74 LERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
126-285 7.01e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.70  E-value: 7.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 126 VTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHH 205
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 206 QMGLCYRARmiqikkatrnkpkgkdklkvyELIRSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKALCL 285
Cdd:COG0457   81 NLGLALQAL---------------------GRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 150-283 9.98e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 9.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 150 AEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRarmiqikkatrnkpkgk 229
Cdd:COG4783   21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL----------------- 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 397701909 230 dKLKVYElirSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG4783   84 -KAGDYD---EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 54-251 1.02e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 53.45  E-value: 1.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   54 ERPEIDCEKGWALLKFG--------GKYYQKAKAAFEKALEVEPDNPEFNIGYAIT-VYRLDDSDREGSvksfsLGPLRK 124
Cdd:TIGR00990 282 DSNELDEETGNGQLQLGlkspeskaDESYEEAARAFEKALDLGKLGEKEAIALNLRgTFKCLKGKHLEA-----LADLSK 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  125 AVTLNP--DNSYIKvfLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSF 202
Cdd:TIGR00990 357 SIELDPrvTQSYIK--RASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIF 434

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 397701909  203 LHHQMG-LCYR-----ARMIQIKKATRNKPKGKDKLKVYELIRSAIFHFKAAVEQ 251
Cdd:TIGR00990 435 SHIQLGvTQYKegsiaSSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEK 489
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 172-324 3.07e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 3.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 172 YAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRAR-----MIQI-KKATRNKPK--------GKDKLKVYEL 237
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRgeydrAIRIhQKLLERDPDraeallelAQDYLKAGLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 238 IRsAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKALclgnitDDHKHQIHYHYGRFQEFHCKSE-NTAIH 316
Cdd:COG2956   93 DR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLL------KLGPENAHAYCELAELYLEQGDyDEAIE 165


                 ....*...
gi 397701909 317 HYLEALRV 324
Cdd:COG2956  166 ALEKALKL 173
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 54-196 3.56e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 3.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  54 ERPEIDCEKgwALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNS 133
Cdd:COG2956  142 ENAHAYCEL--AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE-------AIAALERALEQDPDYL 212

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 397701909 134 YIKVFLALKLQDVHAEAEGEKYIEEILdQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEA 196
Cdd:COG2956  213 PALPRLAELYEKLGDPEEALELLRKAL-ELDPSDDLLLALADLLERKEGLEAALALLERQLRR 274
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 139-283 1.40e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.61  E-value: 1.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 139 LALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRAR---- 214
Cdd:COG3914   50 ALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALgrle 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 215 --MIQIKKATRNKPkgkDKLKVY----ELIRS------AIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKA 282
Cdd:COG3914  130 eaLAALRRALALNP---DFAEAYlnlgEALRRlgrleeAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRA 206


                 .
gi 397701909 283 L 283
Cdd:COG3914  207 L 207
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
14-196 2.37e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.08  E-value: 2.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  14 TWGNYAWVYYHMDQLREAQKYIDKVgnvcrkLSSPSDYrlerPEIDCEKGWALLKFGgkYYQKAKAAFEKALEVEPDNPE 93
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKA------LELDPDD----AEALYNLGLAYLRLG--RYEEALADYEQALELDPDDAE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  94 FNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYA 173
Cdd:COG0457   78 ALNNLGLALQALGRYEE-------ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150

                        170       180
                 ....*....|....*....|...
gi 397701909 174 AKFYRRKHSWDKALELLKKALEA 196
Cdd:COG0457  151 GIALEKLGRYEEALELLEKLEAA 173
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 75-283 3.31e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 3.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   75 QKAKAAFEKALEVEPDNPEfnigyaiTVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEK 154
Cdd:TIGR02917 618 NKAVSSFKKLLALQPDSAL-------ALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKK 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  155 YIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLhhqmglcyrARMIQIKKATRNKPKGkdkLKV 234
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA---------IKLHRALLASGNTAEA---VKT 758

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 397701909  235 YElirsaifhfkAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:TIGR02917 759 LE----------AWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVV 797
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
177-283 3.49e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 3.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 177 YRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRaRMIQIKKATRnkpkgkdklkvyelirsaifhFKAAVEQDSMFA 256
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLL-EQGRYDEAIA---------------------LEKALKLDPNNA 59

                         90       100
                 ....*....|....*....|....*..
gi 397701909 257 FAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG3063   60 EALLNLAELLLELGDYDEALAYLERAL 86
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
14-196 3.73e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.31  E-value: 3.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  14 TWGNYAWVYYHMDQLREAQKYIDKVgnvcrklsspSDYRLERPEIDCEKGWALLKFGgkYYQKAKAAFEKALEVEPDNPE 93
Cdd:COG0457   44 ALYNLGLAYLRLGRYEEALADYEQA----------LELDPDDAEALNNLGLALQALG--RYEEALEDYDKALELDPDDAE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  94 FNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYA 173
Cdd:COG0457  112 ALYNLGLALLELGRYDE-------AIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALG 184

                        170       180
                 ....*....|....*....|...
gi 397701909 174 AKFYRRKHSWDKALELLKKALEA 196
Cdd:COG0457  185 EAALALAAAEVLLALLLALEQAL 207
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 122-283 5.79e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 5.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 122 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSS 201
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 202 FLHHQMGLCYRARmiqikkatrnkpkgkdklkvyELIRSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQK 281
Cdd:COG5010   89 ELYYNLALLYSRS---------------------GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                 ..
gi 397701909 282 AL 283
Cdd:COG5010  148 AL 149
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 169-283 6.19e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.18  E-value: 6.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 169 VLRYAAKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRARmiqikkatrnkpkGKdklkvyelIRSAIFHFKAA 248
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQL-------------GD--------LDEAIVLLHEA 64

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 397701909 249 VEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG4783   65 LELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 15-132 2.42e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 2.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  15 WGNYAWVYYHMDQLREAQKYIDKVgnvcRKLsSPSDyrlerPEIDCEKGWALLKFGgkYYQKAKAAFEKALEVEPDNPEF 94
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEA----LEL-DPDE-----PEARLNLGLALLKAG--DYDEALALLEKALKLDPEHPEA 108

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 397701909  95 NIGYAITVYRLDDSDREGSVksfslgpLRKAVTLNPDN 132
Cdd:COG4783  109 YLRLARAYRALGRPDEAIAA-------LEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 69-283 4.16e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 4.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   69 FGGKYYQKAKAAFEKALEVEPDNPEFNIGYAitVYRLDDSDREGSVKSFSlgplrKAVTLNPDNsyIKVFLAL-KLQDVH 147
Cdd:TIGR02917 476 LGKGDLAKAREAFEKALSIEPDFFPAAANLA--RIDIQEGNPDDAIQRFE-----KVLTIDPKN--LRAILALaGLYLRT 546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  148 A-EAEGEKYIEEI--LDQISFQPYVLryAAKFYRRKHSWDKALELLKKALEATPTSsflhhqmglcyrARMIQIKkaTRN 224
Cdd:TIGR02917 547 GnEEEAVAWLEKAaeLNPQEIEPALA--LAQYYLGKGQLKKALAILNEAADAAPDS------------PEAWLML--GRA 610

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 397701909  225 KPKGKDKlkvyeliRSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:TIGR02917 611 QLAAGDL-------NKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRAL 662
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 174-283 8.16e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 8.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 174 AKFYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRArmiqikkaTRNKPKgkdklkvyelirsAIFHFKAAVEQDS 253
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLA--------AGDTEE-------------AEELLERALALDP 82

                         90       100       110
                 ....*....|....*....|....*....|
gi 397701909 254 MFAFAYTDLANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG4235   83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 63-315 8.94e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 8.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   63 GWALLKFGGkyYQKAKAAFEKALEVEPDNPEFNIGYAITvyRLDDSDREGSVKSfslgpLRKAVTLNPDNSYIKVFLALK 142
Cdd:TIGR02917 370 GEAYLALGD--FEKAAEYLAKATELDPENAAARTQLGIS--KLSQGDPSEAIAD-----LETAAQLDPELGRADLLLILS 440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  143 lqdvhaeaegekyieeildqisfqpyvlryaakfYRRKHSWDKALELLKKALEATPTSSFLHHQMGLCYRARmiqikkat 222
Cdd:TIGR02917 441 ----------------------------------YLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGK-------- 478

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  223 rnkpkgKDKLKvyelirsAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKALclgnITDDHKHQIHYHYGR 302
Cdd:TIGR02917 479 ------GDLAK-------AREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVL----TIDPKNLRAILALAG 541

                         250
                  ....*....|...
gi 397701909  303 FQEFHCKSENTAI 315
Cdd:TIGR02917 542 LYLRTGNEEEAVA 554
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 241-323 1.04e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.83  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 241 AIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNAEDIFQKALclgNITDDHkHQIHYHYGR-FQEFHCKSEntAIHHYL 319
Cdd:COG3914   97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRAL---ALNPDF-AEAYLNLGEaLRRLGRLEE--AIAALR 170


                 ....
gi 397701909 320 EALR 323
Cdd:COG3914  171 RALE 174
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 74-234 1.19e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.83  E-value: 1.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDregsvksFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG3914  128 LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE-------EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAI 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLK--KALEATP---TSSFLHHQMGL-------CYRARMIQIKKA 221
Cdd:COG3914  201 AAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEEllAALARGPselSPFALLYLPDDdpaellaLARAWAQLVAAA 280

                        170       180
                 ....*....|....*....|
gi 397701909 222 T-------RNKPKGKDKLKV 234
Cdd:COG3914  281 AapelpppPNPRDPDRKLRI 300
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
74-161 3.90e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 3.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfsLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 153
Cdd:COG3063    8 LEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE--------AIALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                 ....*...
gi 397701909 154 KYIEEILD 161
Cdd:COG3063   80 AYLERALE 87
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 64-161 4.54e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 4.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   64 WALLKfggKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKL 143
Cdd:TIGR02917 812 WLYLE---LKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADR-------ALPLLRKAVNIAPEAAAIRYHLALAL 881

                          90
                  ....*....|....*...
gi 397701909  144 QDVHAEAEGEKYIEEILD 161
Cdd:TIGR02917 882 LATGRKAEARKELDKLLN 899
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 185-324 7.74e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 7.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 185 KALELLKKALEATPTSSFLHHQMGLCYRARmiqikkatrnkpkgkdklkvyELIRSAIFHFKAAVEQDSMFAFAYTDLAN 264
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRL---------------------GRYDEALAAYEKALRLDPDNADALLDLAE 59

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 397701909 265 MYAEGGQYSNAEDIFQKALCLgnitdDHKH--------QIHYHYGRFQEfhcksentAIHHYLEALRV 324
Cdd:COG4235   60 ALLAAGDTEEAEELLERALAL-----DPDNpealyllgLAAFQQGDYAE--------AIAAWQKLLAL 114
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 76-282 8.52e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909   76 KAKAAFEKALEVEPDNPEFNIG---YAITVYRLDDS----------------------DREGSVKSF--SLGPLRKAVTL 128
Cdd:TIGR02917 143 LAQKSYEQALAIDPRSLYAKLGlaqLALAENRFDEAralidevltadpgnvdalllkgDLLLSLGNIelALAAYRKAIAL 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  129 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATP---TSSFL-- 203
Cdd:TIGR02917 223 RPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylPALLLag 302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  204 --HHQMGLCYRAR--MIQIKKATRNKPKGKDKLKVYEL----IRSAIFHFKAAVEQDSMFAFAYTDLANMYAEGGQYSNA 275
Cdd:TIGR02917 303 asEYQLGNLEQAYqyLNQILKYAPNSHQARRLLASIQLrlgrVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKA 382


                  ....*..
gi 397701909  276 EDIFQKA 282
Cdd:TIGR02917 383 AEYLAKA 389
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 15-133 9.94e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 9.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  15 WGNYAWVYYHMDQLREAQKYIDKVgnvcrklsspsdYRL--ERPEIDCEKGWALLKFGGkyYQKAKAAFEKALEVEPDNP 92
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKA------------LRLdpDNADALLDLAEALLAAGD--TEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 397701909  93 EFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNS 133
Cdd:COG4235   86 EALYLLGLAAFQQGDYAE-------AIAAWQKLLALLPADA 119
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 74-208 1.80e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  74 YQKAKAAFEKALEVEPDNPEFNIGYAiTVYrLDDSDREGSVKSFslgplRKAVTLNPDNSYIKvFlaLKLQDVHAEAEGE 153
Cdd:cd24142   16 FELALKFLQRALELEPNNVEALELLG-EIL-LELGDVEEAREVL-----LRAIELDPDGGYEK-Y--LYLGQLSGGEEAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 154 KYIE-------EILDQISFQPYVLRYAAKFYRRKHS---------W-----------DKALELLKKALEATPTSSFLHHQ 206
Cdd:cd24142   86 QYYEkgieileEELQALQAASAEAEEEAEELKRKLSsalcalaeiYmtdlcdepdaeQRCEELITKALELDPTNPEALQT 165


                 ..
gi 397701909 207 MG 208
Cdd:cd24142  166 LA 167
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 65-283 2.36e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 2.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909  65 ALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNS----YIKVFLA 140
Cdd:COG3071   23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYER-------RDEYLAQALELAPEAElavlLTRAELL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 141 LKLQDVHaeaEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLK-----KALEATPTSSFLHHqmglCYRARM 215
Cdd:COG3071   96 LDQGQAE---QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPalrkhKALSAEEAQALERR----AYLGLL 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 397701909 216 iqikkatRNKPKGKDKLkvyeliRSAIFHFKAAVEQDSMFAFAYtdlANMYAEGGQYSNAEDIFQKAL 283
Cdd:COG3071  169 -------RQAARDAEAL------KALWKALPRAERRDPELAAAY---ARALIALGDHDEAERLLREAL 220
PGA_TPR_OMP TIGR03939
poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Members of this protein family are the ...
 165-200 3.76e-03

poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.


Pssm-ID: 274868 [Multi-domain]  Cd Length: 800  Bit Score: 38.87  E-value: 3.76e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 397701909  165 FQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTS 200
Cdd:TIGR03939  84 LPARVLEALAKAYRNEKQWDKALELYRKLLQRDPNN 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 122-214 4.15e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.91  E-value: 4.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 397701909 122 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISFQPYVLRYAAKFYRRKHSWDKALELLKKALEATPTSS 201
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90
                 ....*....|...
gi 397701909 202 FLHHQMGLCYRAR 214
Cdd:COG4235   86 EALYLLGLAAFQQ 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH