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Conserved domains on  [gi|397701885|gb|AFO59652|]
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zinc fingers and homeoboxes protein 1, partial [Microcebus griseorufus]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10647766)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  21557080|26464018|27768937|1357790
SCOP:  4000291

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 128-179 3.10e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


:

Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.18  E-value: 3.10e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 397701885   128 CKKSPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWK 179
Cdd:smart00389   6 TSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 41-84 1.85e-05

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


:

Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 41.08  E-value: 1.85e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 397701885    41 EQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKK 84
Cdd:smart00389  11 EQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRA 54
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 128-179 3.10e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.18  E-value: 3.10e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 397701885   128 CKKSPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWK 179
Cdd:smart00389   6 TSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 128-180 5.97e-10

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 53.40  E-value: 5.97e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 397701885 128 CKKSPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKN 180
Cdd:cd00086    5 TRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 41-84 1.85e-05

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 41.08  E-value: 1.85e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 397701885    41 EQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKK 84
Cdd:smart00389  11 EQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRA 54
Homeodomain pfam00046
Homeodomain;
131-180 2.43e-05

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 40.95  E-value: 2.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 397701885  131 SPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKN 180
Cdd:pfam00046   8 TPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 41-79 4.15e-05

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 40.30  E-value: 4.15e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 397701885  41 EQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWF 79
Cdd:cd00086   10 EQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWF 48
Homeodomain pfam00046
Homeodomain;
40-79 9.34e-03

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 33.63  E-value: 9.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 397701885   40 AEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWF 79
Cdd:pfam00046   9 PEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWF 48
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 128-179 3.10e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.18  E-value: 3.10e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 397701885   128 CKKSPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWK 179
Cdd:smart00389   6 TSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 128-180 5.97e-10

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 53.40  E-value: 5.97e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 397701885 128 CKKSPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKN 180
Cdd:cd00086    5 TRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 41-84 1.85e-05

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 41.08  E-value: 1.85e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 397701885    41 EQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKK 84
Cdd:smart00389  11 EQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRA 54
Homeodomain pfam00046
Homeodomain;
131-180 2.43e-05

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 40.95  E-value: 2.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 397701885  131 SPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKN 180
Cdd:pfam00046   8 TPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 41-79 4.15e-05

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 40.30  E-value: 4.15e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 397701885  41 EQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWF 79
Cdd:cd00086   10 EQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWF 48
Homeodomain pfam00046
Homeodomain;
40-79 9.34e-03

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 33.63  E-value: 9.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 397701885   40 AEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWF 79
Cdd:pfam00046   9 PEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWF 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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