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Conserved domains on  [gi|39645238|gb|AAH07938|]
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Minichromosome maintenance complex component 2 [Homo sapiens]

Protein Classification

MCM_N and AAA domain-containing protein( domain architecture ID 11674013)

protein containing domains MCM2_N, MCM_N, and AAA

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MCM smart00350
minichromosome maintenance proteins;
291-803 0e+00

minichromosome maintenance proteins;


:

Pssm-ID: 214631 [Multi-domain]  Cd Length: 509  Bit Score: 818.04  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    291 VEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSqNQEVKPGSCP--ECQSAGPFEVNMEET 368
Cdd:smart00350   2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQS-GRETEPTVCPprECQSPTPFSLNHERS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    369 IYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNN-YDGSLNTANGFPVFATVILANHVAKK 447
Cdd:smart00350  81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    448 DNKVA-------VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 520
Cdd:smart00350 161 DYKRSfedssfsVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINIL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    521 LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
Cdd:smart00350 241 LCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAI 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVV 680
Cdd:smart00350 321 HEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVV 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    681 GSHVRHHPSNKEEEGlangsaaepampntygvEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMAT--- 757
Cdd:smart00350 401 DLHRYSHPEEDEAFE-----------------PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesr 463
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 39645238    758 GSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
MCM_N pfam14551
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
197-287 2.32e-20

MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.


:

Pssm-ID: 464206 [Multi-domain]  Cd Length: 95  Bit Score: 86.58  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   197 HRFKNFLRT-HVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVV--LAMYPK 273
Cdd:pfam14551   2 RKFKDFLEEfREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVkeLSEDPD 81
                          90
                  ....*....|....
gi 39645238   274 YDRITNHIHVRISH 287
Cdd:pfam14551  82 YAEEEKEFQVRFYN 95
MCM2_N super family cl13991
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ...
73-182 1.26e-15

Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.


The actual alignment was detected with superfamily member pfam12619:

Pssm-ID: 403724  Cd Length: 148  Bit Score: 74.75  E-value: 1.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    73 IGDGMERDYRAIPELDAYEAEGLaLDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE------- 145
Cdd:pfam12619  28 FGDNMEDDYRQNPELDRYDLDDI-DDEGDYEEMDAAERRRAEAQLNRRDRELGAARRRRPAAFLQDDDDEDDLdgdyglp 106
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 39645238   146 -RPARKRRQV-ERATEDGEED-EEMIE--SIENLEDLKGHSV 182
Cdd:pfam12619 107 iQRRRRRRHYdEDQDEDMDEDiDPFEEelSLESLADVKADSI 148
 
Name Accession Description Interval E-value
MCM smart00350
minichromosome maintenance proteins;
291-803 0e+00

minichromosome maintenance proteins;


Pssm-ID: 214631 [Multi-domain]  Cd Length: 509  Bit Score: 818.04  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    291 VEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSqNQEVKPGSCP--ECQSAGPFEVNMEET 368
Cdd:smart00350   2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQS-GRETEPTVCPprECQSPTPFSLNHERS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    369 IYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNN-YDGSLNTANGFPVFATVILANHVAKK 447
Cdd:smart00350  81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    448 DNKVA-------VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 520
Cdd:smart00350 161 DYKRSfedssfsVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINIL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    521 LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
Cdd:smart00350 241 LCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAI 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVV 680
Cdd:smart00350 321 HEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVV 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    681 GSHVRHHPSNKEEEGlangsaaepampntygvEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMAT--- 757
Cdd:smart00350 401 DLHRYSHPEEDEAFE-----------------PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesr 463
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 39645238    758 GSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
MCM2 cd17753
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ...
476-801 0e+00

DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350659 [Multi-domain]  Cd Length: 325  Bit Score: 700.74  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17753   1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17753  81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSaAEPAMPNTYGVEPL 715
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEK-NQRQRPKETKVEPI 239
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17753 240 PQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAI 319

                ....*.
gi 39645238 796 RVMLES 801
Cdd:cd17753 320 RVMLDS 325
minchrom_main_MCM NF040949
minichromosome maintenance protein MCM;
195-874 0e+00

minichromosome maintenance protein MCM;


Pssm-ID: 468880 [Multi-domain]  Cd Length: 681  Bit Score: 596.14  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKY 274
Cdd:NF040949   1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  275 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC--NFVLGPFCQSQNQEVKPGS- 351
Cdd:NF040949  81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEESYEIVEPPTv 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  352 CPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTaNG 431
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK-GS 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  432 FPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKH 511
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  512 KVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDK 591
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  592 MNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQ 671
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  672 DEMLARFVVGSHvrhhpsnKEEEGLANgsaaepampntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR 751
Cdd:NF040949 480 DRRLARHILDVH-------SGKEKVKP---------------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMR 537
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  752 KESMATGS----IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVML----------ES-FIDTQKFSVMRSMRK 816
Cdd:NF040949 538 KSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidvETgKIDIDTIMTGKPKSK 617
                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238  817 tfarylsfrRDNNELLLFILKQLVAEQVtyqrnrfgaqqdtiEVPEKDLVDKARQINI 874
Cdd:NF040949 618 ---------REKMSKIVEIIKELEEEEE--------------CVKIKELIKEAEKKGI 652
Mcm2 COG1241
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ...
194-874 0e+00

DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];


Pssm-ID: 440854 [Multi-domain]  Cd Length: 682  Bit Score: 582.91  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRThvdshghNVFKERISDMCKE--NRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAmy 271
Cdd:COG1241   4 DLVDKFEEFLRR-------YKYRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE-- 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 272 pKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCN---FVLgpfcQSQNQEVK 348
Cdd:COG1241  75 -PYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGtetYVP----QTGEKLQE 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 349 PGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428
Cdd:COG1241 150 PHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 429 ANgfPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG 508
Cdd:COG1241 230 KS--TIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 509 GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQR-HPVSREWTLEAGALVLADRGVCLID 587
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLACID 387
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTV 667
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 668 DPVQDEMLARFVVGSHvrhhpSNKEEEGLANGSAAEPAMPntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMY 747
Cdd:COG1241 468 DEERDRELARHILKVH-----RAGELLEQEIEEETEEVKP------EIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFY 536
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 748 SDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESF------IDTQKF---SVMRSMRKT 817
Cdd:COG1241 537 VDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLkdvgvdPETGKFdidVIETGTSKS 616
                       650       660       670       680       690
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 39645238 818 farylsfRRDNNELLLFILKQLVAEQVTYqrnrfgaqqdtieVPEKDLVDKARQINI 874
Cdd:COG1241 617 -------QRDKMKLIKDIIKELEEESSGG-------------APIEDVIEEAEEEGI 653
MCM pfam00493
MCM P-loop domain;
460-683 2.79e-139

MCM P-loop domain;


Pssm-ID: 459830 [Multi-domain]  Cd Length: 224  Bit Score: 413.46  E-value: 2.79e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   460 DVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 539
Cdd:pfam00493   1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   540 SSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTS 619
Cdd:pfam00493  81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238   620 LQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSH 683
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
PTZ00111 PTZ00111
DNA replication licensing factor MCM4; Provisional
194-804 8.81e-87

DNA replication licensing factor MCM4; Provisional


Pssm-ID: 173403 [Multi-domain]  Cd Length: 915  Bit Score: 296.91  E-value: 8.81e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  194 EIHHRFKNFLRTHVDSHGHNVFKE---------------RISDMCKENRESLVVNYEDLAARE----HVLAY------FL 248
Cdd:PTZ00111  87 ELSERFTNFLKNFTEFSDVLEFKDeqqskpeytelyylwKLMNFIKENLRDHSTGYSRILPFEvdlmHVYSFdkvlykLL 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  249 PEAPAELLQIFDEAALEVVLAMYPKYDRITN------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQL 322
Cdd:PTZ00111 167 VTFPADCIAELDKVLVKLFNELLSKHYSDLSlennsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEI 246
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  323 SMVKYNC-----------NKCNF-VLGPFCQSQNQEvkPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRL 390
Cdd:PTZ00111 247 TMACFRCrgqkkiglndyQPCTCeHYEYVIQGEVNE--PLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  391 PRSKDAI--------------------LLADLVDSCKPGDEIELTGIYH------NNYDGSLNTAngFPVFATVIL---- 440
Cdd:PTZ00111 325 DGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHvkvi 402
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  441 ----ANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEP------KNPGG 509
Cdd:PTZ00111 403 nstnANQPEKGLKYLGnENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPDA 482
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  510 KHKV---RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQ-RHPVSREWTLEAGALVLADRGVCL 585
Cdd:PTZ00111 483 CYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  586 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRD 665
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  666 TVDPVQDEMLARFVVGSHVRHH--PSNKEEEGL--ANGSAAEPAMPNT---YGVEPLpqEVLKKYIIYAKERVHPKLNQM 738
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtGSGNDEDTYdrSNTMHVEDESLRSekdYNKNDL--DMLRMYIKFSKLHCFPKLSDE 720
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  739 DQDKVAKMY------------------------SDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:PTZ00111 721 AKKVITREYvkmrqgnfqtsnldelehaqedddDDLYYQSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
                        730
                 ....*....|....
gi 39645238  795 IRVM----LESFID 804
Cdd:PTZ00111 801 VQIVksstFQSLVD 814
MCM_N pfam14551
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
197-287 2.32e-20

MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.


Pssm-ID: 464206 [Multi-domain]  Cd Length: 95  Bit Score: 86.58  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   197 HRFKNFLRT-HVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVV--LAMYPK 273
Cdd:pfam14551   2 RKFKDFLEEfREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVkeLSEDPD 81
                          90
                  ....*....|....
gi 39645238   274 YDRITNHIHVRISH 287
Cdd:pfam14551  82 YAEEEKEFQVRFYN 95
MCM2_N pfam12619
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ...
73-182 1.26e-15

Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.


Pssm-ID: 403724  Cd Length: 148  Bit Score: 74.75  E-value: 1.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    73 IGDGMERDYRAIPELDAYEAEGLaLDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE------- 145
Cdd:pfam12619  28 FGDNMEDDYRQNPELDRYDLDDI-DDEGDYEEMDAAERRRAEAQLNRRDRELGAARRRRPAAFLQDDDDEDDLdgdyglp 106
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 39645238   146 -RPARKRRQV-ERATEDGEED-EEMIE--SIENLEDLKGHSV 182
Cdd:pfam12619 107 iQRRRRRRHYdEDQDEDMDEDiDPFEEelSLESLADVKADSI 148
 
Name Accession Description Interval E-value
MCM smart00350
minichromosome maintenance proteins;
291-803 0e+00

minichromosome maintenance proteins;


Pssm-ID: 214631 [Multi-domain]  Cd Length: 509  Bit Score: 818.04  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    291 VEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSqNQEVKPGSCP--ECQSAGPFEVNMEET 368
Cdd:smart00350   2 PSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQS-GRETEPTVCPprECQSPTPFSLNHERS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    369 IYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNN-YDGSLNTANGFPVFATVILANHVAKK 447
Cdd:smart00350  81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVpYGFKLNTVKGLPVFATYIEANHVRKL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    448 DNKVA-------VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVL 520
Cdd:smart00350 161 DYKRSfedssfsVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGDINIL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    521 LCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
Cdd:smart00350 241 LCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAI 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVV 680
Cdd:smart00350 321 HEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVV 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    681 GSHVRHHPSNKEEEGlangsaaepampntygvEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMAT--- 757
Cdd:smart00350 401 DLHRYSHPEEDEAFE-----------------PPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTesr 463
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 39645238    758 GSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
Cdd:smart00350 464 SSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
MCM2 cd17753
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ...
476-801 0e+00

DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350659 [Multi-domain]  Cd Length: 325  Bit Score: 700.74  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17753   1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17753  81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSaAEPAMPNTYGVEPL 715
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEK-NQRQRPKETKVEPI 239
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17753 240 PQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAI 319

                ....*.
gi 39645238 796 RVMLES 801
Cdd:cd17753 320 RVMLDS 325
minchrom_main_MCM NF040949
minichromosome maintenance protein MCM;
195-874 0e+00

minichromosome maintenance protein MCM;


Pssm-ID: 468880 [Multi-domain]  Cd Length: 681  Bit Score: 596.14  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKY 274
Cdd:NF040949   1 LGEKFKEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIVEEEDPEY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  275 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKC--NFVLGPFCQSQNQEVKPGS- 351
Cdd:NF040949  81 AEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCgcEFEWPEEEEESYEIVEPPTv 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  352 CPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTaNG 431
Cdd:NF040949 161 CPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK-GS 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  432 FPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKH 511
Cdd:NF040949 240 RPIFKNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGT 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  512 KVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDK 591
Cdd:NF040949 320 RIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDK 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  592 MNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQ 671
Cdd:NF040949 400 MREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEER 479
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  672 DEMLARFVVGSHvrhhpsnKEEEGLANgsaaepampntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR 751
Cdd:NF040949 480 DRRLARHILDVH-------SGKEKVKP---------------EIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMR 537
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  752 KESMATGS----IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVML----------ES-FIDTQKFSVMRSMRK 816
Cdd:NF040949 538 KSSKSSEDpdspIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLaflesvgidvETgKIDIDTIMTGKPKSK 617
                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238  817 tfarylsfrRDNNELLLFILKQLVAEQVtyqrnrfgaqqdtiEVPEKDLVDKARQINI 874
Cdd:NF040949 618 ---------REKMSKIVEIIKELEEEEE--------------CVKIKELIKEAEKKGI 652
Mcm2 COG1241
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ...
194-874 0e+00

DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];


Pssm-ID: 440854 [Multi-domain]  Cd Length: 682  Bit Score: 582.91  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 194 EIHHRFKNFLRThvdshghNVFKERISDMCKE--NRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAmy 271
Cdd:COG1241   4 DLVDKFEEFLRR-------YKYRDEILELAQEypEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALREIDLE-- 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 272 pKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCN---FVLgpfcQSQNQEVK 348
Cdd:COG1241  75 -PYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGtetYVP----QTGEKLQE 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 349 PGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428
Cdd:COG1241 150 PHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRG 229
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 429 ANgfPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG 508
Cdd:COG1241 230 KS--TIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLP 307
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 509 GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQR-HPVSREWTLEAGALVLADRGVCLID 587
Cdd:COG1241 308 DGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRdDFGTGRWTLEAGALVLADGGLACID 387
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTV 667
Cdd:COG1241 388 ELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKP 467
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 668 DPVQDEMLARFVVGSHvrhhpSNKEEEGLANGSAAEPAMPntygvePLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMY 747
Cdd:COG1241 468 DEERDRELARHILKVH-----RAGELLEQEIEEETEEVKP------EIDPDLLRKYIAYARRNVFPVLTEEAKDLIEDFY 536
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 748 SDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESF------IDTQKF---SVMRSMRKT 817
Cdd:COG1241 537 VDMRKkGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLkdvgvdPETGKFdidVIETGTSKS 616
                       650       660       670       680       690
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 39645238 818 farylsfRRDNNELLLFILKQLVAEQVTYqrnrfgaqqdtieVPEKDLVDKARQINI 874
Cdd:COG1241 617 -------QRDKMKLIKDIIKELEEESSGG-------------APIEDVIEEAEEEGI 653
MCM cd17706
MCM helicase family; MCM helicases are a family of helicases that play an important role in ...
476-801 1.00e-145

MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).


Pssm-ID: 350658 [Multi-domain]  Cd Length: 311  Bit Score: 433.69  E-value: 1.00e-145
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17706   1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17706  81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGlANGSaaepampntygvePL 715
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKPE-EDGI-------------PI 226
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17706 227 DIELLRKYILYAR-QIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAI 305

                ....*.
gi 39645238 796 RVMLES 801
Cdd:cd17706 306 RLVRHS 311
MCM pfam00493
MCM P-loop domain;
460-683 2.79e-139

MCM P-loop domain;


Pssm-ID: 459830 [Multi-domain]  Cd Length: 224  Bit Score: 413.46  E-value: 2.79e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   460 DVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 539
Cdd:pfam00493   1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   540 SSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTS 619
Cdd:pfam00493  81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238   620 LQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSH 683
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
MCM5 cd17756
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ...
476-801 5.61e-125

DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350662 [Multi-domain]  Cd Length: 317  Bit Score: 380.19  E-value: 5.61e-125
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17756   1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17756  81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSnkEEEGLANGSaaepampntygvepL 715
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKA--SQSQENEGE--------------I 224
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK-------ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIE 788
Cdd:cd17756 225 PISKLKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRKdvrqnelESDNRSSIPITVRQLEAIIRISESLAKMELSPIATE 304
                       330
                ....*....|...
gi 39645238 789 DDVNMAIRVMLES 801
Cdd:cd17756 305 KHVEEAIRLFQVS 317
MCM_arch cd17761
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ...
475-799 4.14e-122

archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork


Pssm-ID: 350667 [Multi-domain]  Cd Length: 308  Bit Score: 372.17  E-value: 4.14e-122
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 475 EKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAV 554
Cdd:cd17761   1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 634
Cdd:cd17761  81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 635 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEglangsaaepampntygvep 714
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPE-------------------- 220
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 715 LPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGS-IPITVRHIESMIRMAEAHARIHLRDYVIEDDVNM 793
Cdd:cd17761 221 IDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAER 300

                ....*.
gi 39645238 794 AIRVML 799
Cdd:cd17761 301 AIRIML 306
MCM4 cd17755
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ...
480-801 6.89e-119

DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350661 [Multi-domain]  Cd Length: 309  Bit Score: 364.06  E-value: 6.89e-119
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 480 SIAPSIYGHEDIKRGLALALFGGEPKNPG-GKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTA 558
Cdd:cd17755   5 SIAPSIYELEDVKKGILLQLFGGTRKDFTkTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAVGLTA 84
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 559 YVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYD 638
Cdd:cd17755  85 YVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIGSRYN 164
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 639 PSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGlangsaaepampntygvepLPQE 718
Cdd:cd17755 165 PKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEV-------------------LDVE 225
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 719 VLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK-ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRV 797
Cdd:cd17755 226 VLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKmGSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRL 305

                ....
gi 39645238 798 MLES 801
Cdd:cd17755 306 IREA 309
MCM6 cd17757
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ...
476-801 1.33e-117

DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350663 [Multi-domain]  Cd Length: 307  Bit Score: 360.53  E-value: 1.33e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17757   1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17757  81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHhpsnkeEEGLANgsaaepampntygvePL 715
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKR------EEAIEP---------------PF 219
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 716 PQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATG---SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVN 792
Cdd:cd17757 220 TAEQLKRYIAYAR-TFKPKLTKEAKDELVEQYKELRQDDASGStrsSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVE 298

                ....*....
gi 39645238 793 MAIRVMLES 801
Cdd:cd17757 299 EAARLLKKS 307
MCM7 cd17758
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ...
476-798 1.11e-112

DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350664 [Multi-domain]  Cd Length: 306  Bit Score: 347.47  E-value: 1.11e-112
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 476 KIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKhKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVG 555
Cdd:cd17758   1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGM-KIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 556 LTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
Cdd:cd17758  80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSnkeeeglangsaaepampntyGVE 713
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVtyVHQHNKQPDS---------------------DFE 218
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 714 PLPQEVLKKYIIYAKeRVHPKLNQMDQDKVAKMYSDLRKESMATGSIP-ITVRHIESMIRMAEAHARIHLRDYVIEDDVN 792
Cdd:cd17758 219 PLDPKLLRAYIALAK-RKRPTVPPALADYIVQAYVEMRQEAKRSKDFTfTTPRTLLAILRLSQALARLRLSDSVEIDDVE 297

                ....*.
gi 39645238 793 MAIRVM 798
Cdd:cd17758 298 EALRLM 303
MCM3 cd17754
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ...
480-798 3.11e-105

DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.


Pssm-ID: 350660 [Multi-domain]  Cd Length: 299  Bit Score: 327.89  E-value: 3.11e-105
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 480 SIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAY 559
Cdd:cd17754   5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTAA 84
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 560 VQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDP 639
Cdd:cd17754  85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGRYDV 164
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 640 SLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHvRHhpsnkeeeglangsaaepampntygveplpQEV 719
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMH-RY------------------------------IKF 213
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 720 LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRK----ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAI 795
Cdd:cd17754 214 LRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNddntKTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVAL 293

                ...
gi 39645238 796 RVM 798
Cdd:cd17754 294 NLL 296
PTZ00111 PTZ00111
DNA replication licensing factor MCM4; Provisional
194-804 8.81e-87

DNA replication licensing factor MCM4; Provisional


Pssm-ID: 173403 [Multi-domain]  Cd Length: 915  Bit Score: 296.91  E-value: 8.81e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  194 EIHHRFKNFLRTHVDSHGHNVFKE---------------RISDMCKENRESLVVNYEDLAARE----HVLAY------FL 248
Cdd:PTZ00111  87 ELSERFTNFLKNFTEFSDVLEFKDeqqskpeytelyylwKLMNFIKENLRDHSTGYSRILPFEvdlmHVYSFdkvlykLL 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  249 PEAPAELLQIFDEAALEVVLAMYPKYDRITN------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQL 322
Cdd:PTZ00111 167 VTFPADCIAELDKVLVKLFNELLSKHYSDLSlennsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEI 246
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  323 SMVKYNC-----------NKCNF-VLGPFCQSQNQEvkPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRL 390
Cdd:PTZ00111 247 TMACFRCrgqkkiglndyQPCTCeHYEYVIQGEVNE--PLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDK 324
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  391 PRSKDAI--------------------LLADLVDSCKPGDEIELTGIYH------NNYDGSLNTAngFPVFATVIL---- 440
Cdd:PTZ00111 325 DGLDNSVdnsglngeiymkdnevinlnLYDDLIDSVKTGDRVTVVGILKvtpirtSTTRRTLKSL--YTYFVNVIHvkvi 402
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  441 ----ANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEP------KNPGG 509
Cdd:PTZ00111 403 nstnANQPEKGLKYLGnENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKnssdfnKSPDA 482
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  510 KHKV---RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQ-RHPVSREWTLEAGALVLADRGVCL 585
Cdd:PTZ00111 483 CYKVdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCC 562
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  586 IDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRD 665
Cdd:PTZ00111 563 IDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLD 642
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  666 TVDPVQDEMLARFVVGSHVRHH--PSNKEEEGL--ANGSAAEPAMPNT---YGVEPLpqEVLKKYIIYAKERVHPKLNQM 738
Cdd:PTZ00111 643 HIDQDTDQLISLSIAKDFLLPHmtGSGNDEDTYdrSNTMHVEDESLRSekdYNKNDL--DMLRMYIKFSKLHCFPKLSDE 720
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  739 DQDKVAKMY------------------------SDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:PTZ00111 721 AKKVITREYvkmrqgnfqtsnldelehaqedddDDLYYQSSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
                        730
                 ....*....|....
gi 39645238  795 IRVM----LESFID 804
Cdd:PTZ00111 801 VQIVksstFQSLVD 814
MCM9 cd17760
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ...
477-798 2.51e-86

DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).


Pssm-ID: 350666 [Multi-domain]  Cd Length: 299  Bit Score: 277.89  E-value: 2.51e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 477 IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGL 556
Cdd:cd17760   2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 557 TAYVQRHpvSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPiGGR 636
Cdd:cd17760  82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 637 YDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHvrhhPSNKEEEGLangsaaepampntygvepLP 716
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENK----GEPSKSSKL------------------WS 216
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 717 QEVLKKYIIYAKERvHPKLNQmDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIR 796
Cdd:cd17760 217 MEKMRTYFCLIKNL-RPVLSD-EANAILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVS 294

                ..
gi 39645238 797 VM 798
Cdd:cd17760 295 VM 296
MCM8 cd17759
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ...
477-801 1.51e-79

DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).


Pssm-ID: 350665 [Multi-domain]  Cd Length: 289  Bit Score: 259.39  E-value: 1.51e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 477 IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGK--HKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAV 554
Cdd:cd17759   2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 555 GLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQdRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 634
Cdd:cd17759  82 GLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQ-HQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 635 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLArfvvgshvRHHpsnkeeeglangsaaepampntygvep 714
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLS--------EHH--------------------------- 205
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 715 lpqEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMA 794
Cdd:cd17759 206 ---QLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDV 282

                ....*..
gi 39645238 795 IRVMLES 801
Cdd:cd17759 283 IEIMKES 289
MCM_OB pfam17207
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ...
294-418 5.75e-46

MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.


Pssm-ID: 465381 [Multi-domain]  Cd Length: 126  Bit Score: 160.73  E-value: 5.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQsqnqevKPGSC--PECQSAGPFEVNMEETIYQ 371
Cdd:pfam17207   2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKIT------EPTKCpnPECGNKDPFKLVHEKSKFV 75
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 39645238   372 NYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIY 418
Cdd:pfam17207  76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIY 122
MCM_lid pfam17855
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
718-802 1.40e-34

MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.


Pssm-ID: 465534 [Multi-domain]  Cd Length: 86  Bit Score: 126.89  E-value: 1.40e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   718 EVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM-ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIR 796
Cdd:pfam17855   1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80

                  ....*.
gi 39645238   797 VMLESF 802
Cdd:pfam17855  81 LLKESL 86
MCM_N pfam14551
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
197-287 2.32e-20

MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.


Pssm-ID: 464206 [Multi-domain]  Cd Length: 95  Bit Score: 86.58  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   197 HRFKNFLRT-HVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVV--LAMYPK 273
Cdd:pfam14551   2 RKFKDFLEEfREDGDGEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVkeLSEDPD 81
                          90
                  ....*....|....
gi 39645238   274 YDRITNHIHVRISH 287
Cdd:pfam14551  82 YAEEEKEFQVRFYN 95
MCM2_N pfam12619
Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is ...
73-182 1.26e-15

Mini-chromosome maintenance protein 2; This domain family is found in eukaryotes, and is typically between 138 and 153 amino acids in length. The family is found in association with pfam00493. Mini-chromosome maintenance (MCM) proteins are essential for DNA replication. These proteins use ATPase activity to perform this function.


Pssm-ID: 403724  Cd Length: 148  Bit Score: 74.75  E-value: 1.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    73 IGDGMERDYRAIPELDAYEAEGLaLDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE------- 145
Cdd:pfam12619  28 FGDNMEDDYRQNPELDRYDLDDI-DDEGDYEEMDAAERRRAEAQLNRRDRELGAARRRRPAAFLQDDDDEDDLdgdyglp 106
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 39645238   146 -RPARKRRQV-ERATEDGEED-EEMIE--SIENLEDLKGHSV 182
Cdd:pfam12619 107 iQRRRRRRHYdEDQDEDMDEDiDPFEEelSLESLADVKADSI 148
PRK09862 PRK09862
ATP-dependent protease;
485-659 3.11e-06

ATP-dependent protease;


Pssm-ID: 182120 [Multi-domain]  Cd Length: 506  Bit Score: 50.75  E-value: 3.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  485 IYGHEDIKRGLALALFGGEpknpggkhkvrgdiNVLLCGDPGTAKSQFLKYI----------EKVSSRAIFTTgqgASAV 554
Cdd:PRK09862 193 VIGQEQGKRGLEITAAGGH--------------NLLLIGPPGTGKTMLASRIngllpdlsneEALESAAILSL---VNAE 255
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238  555 GLTAYVQRHPV-----SREWTL--------EAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQ 621
Cdd:PRK09862 256 SVQKQWRQRPFrsphhSASLTAmvgggaipGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITYP 335
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 39645238  622 ARCTVIAAANPI-GGRYD-------PSLTFSENVDLTEPIISRFDI 659
Cdd:PRK09862 336 ARFQLVAAMNPSpTGHYQgnhnrctPEQTLRYLNRLSGPFLDRFDL 381
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
485-659 1.50e-05

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 46.76  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   485 IYGHEDIKRGLALALFGGepknpggkHkvrgdiNVLLCGDPGTAKS---QFLKYI-------EKVSSRAIfttgqgASAV 554
Cdd:pfam01078   5 VKGQEQAKRALEIAAAGG--------H------NLLMIGPPGSGKTmlaKRLPGIlpplteaEALEVTAI------HSVA 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   555 GL---TAYVQRHP-VSREWTLEAGALV------------LADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVT 618
Cdd:pfam01078  65 GLggdGGLIRRRPfRAPHHSASAAALVgggsiprpgeisLAHNGVLFLDELPEFKRRVLESLRQPLEDGEITISRARAKV 144
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 39645238   619 SLQARCTVIAAANP--IGGRYDPSLTFSENVD--------LTEPIISRFDI 659
Cdd:pfam01078 145 TFPARFQLVAAMNPcpCGYLGDPNKRCRCSPRqirrylsrLSGPLLDRIDL 195
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
475-791 5.51e-05

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 45.93  E-value: 5.51e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 475 EKIFASIAPSIYGHEDIKRGLALALFGGepknpggKHkvrgdinVLLCGDPGTAKSQFLKYIEKVS----SRAIFTTG-Q 549
Cdd:COG0714   4 ARLRAEIGKVYVGQEELIELVLIALLAG-------GH-------LLLEGVPGVGKTTLAKALARALglpfIRIQFTPDlL 69
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 550 GASAVGLTAYVQRhpvSREWTLEAGALVladRGVCLIDEFdkmndqDRTSIH------EAMEQQSISIskAGIVTSLQAR 623
Cdd:COG0714  70 PSDILGTYIYDQQ---TGEFEFRPGPLF---ANVLLADEI------NRAPPKtqsallEAMEERQVTI--PGGTYKLPEP 135
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 624 CTVIAAANPIggryDPSLTFsenvDLTEPIISRFdilcvvrdtvdpvqdemLARFVVGshvrhHPSNKEEEGLANGSAAE 703
Cdd:COG0714 136 FLVIATQNPI----EQEGTY----PLPEAQLDRF-----------------LLKLYIG-----YPDAEEEREILRRHTGR 185
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 704 PampntygVEPLPQEVLKKYIIYAKE-----RVHPKLNQMDQDKVAKM--YSDLRKesmatgsiPITVRHIESMIRMAEA 776
Cdd:COG0714 186 H-------LAEVEPVLSPEELLALQElvrqvHVSEAVLDYIVDLVRATreHPDLRK--------GPSPRASIALLRAARA 250
                       330
                ....*....|....*
gi 39645238 777 HARIHLRDYVIEDDV 791
Cdd:COG0714 251 LALLDGRDYVTPDDV 265
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
518-657 3.71e-04

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 41.51  E-value: 3.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   518 NVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWT-LEAGALVLADR--GVCLIDEFDKMND 594
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTRDTTEEDLFGRRNIDPGGAsWVDGPLVRAARegEIAVLDEINRANP 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 39645238   595 QDRTSIHEAMEQQSISISKAGIVTSLQARC-TVIAAANPIGgrydpsltFSENvDLTEPIISRF 657
Cdd:pfam07728  81 DVLNSLLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLD--------RGLN-ELSPALRSRF 135
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
518-664 4.42e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 41.75  E-value: 4.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238 518 NVLLCGDPGTAKSQFLKYIEKVSSRAIFTT-GQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQD 596
Cdd:cd00009  21 NLLLYGPPGTGKTTLARAIANELFRPGAPFlYLNASDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLSRGA 100
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 39645238 597 RTSIHEAMEQQSISISKagivtslQARCTVIAAANPiggrydpsltfSENVDLTEPIISRFDILCVVR 664
Cdd:cd00009 101 QNALLRVLETLNDLRID-------RENVRVIGATNR-----------PLLGDLDRALYDRLDIRIVIP 150
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
518-632 1.83e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238    518 NVLLCGDPGTAKSQFLK----YIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLE-----AGALVLADR---GVCL 585
Cdd:smart00382   4 VILIVGPPGSGKTTLARalarELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSgelrlRLALALARKlkpDVLI 83
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 39645238    586 IDEFDKMNDQDRtsiheAMEQQSISISKAGIVTSLQARCTVIAAANP 632
Cdd:smart00382  84 LDEITSLLDAEQ-----EALLLLLEELRLLLLLKSEKNLTVILTTND 125
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
519-659 2.26e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 39.11  E-value: 2.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 39645238   519 VLLCGDPGT---------AKSQFLKYIEkVSSRAIFTTGQGASAVGLTAYVQRhpvsrewtLEAGALvladrGVCLIDEF 589
Cdd:pfam00004   1 LLLYGPPGTgkttlakavAKELGAPFIE-ISGSELVSKYVGESEKRLRELFEA--------AKKLAP-----CVIFIDEI 66
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 39645238   590 DKMN-DQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANpiggRYDpsltfsenvDLTEPIISRFDI 659
Cdd:pfam00004  67 DALAgSRGSGGDSESRRVVNQLLTELDGFTSSNSKVIVIAATN----RPD---------KLDPALLGRFDR 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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