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Conserved domains on  [gi|392312781|gb|AFM56403|]
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GP5 glycoprotein [Equine arteritis virus]

Protein Classification

GP5 family envelope glycoprotein( domain architecture ID 11067907)

GP5 family envelope glycoprotein such as Lactate dehydrogenase elevating virus protein X and Lelystad virus glycoprotein 5, a major envelope protein that mediates virion sialic acid-dependent attachment to the sialoadhesin receptor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EAV_GP5 super family cl24525
Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in ...
 1-80 8.02e-48

Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in equine arteritis virus envelope. It is approximately 80 amino acids in length and is found in association with pfam00951.


The actual alignment was detected with superfamily member pfam15981:

Pssm-ID: 292603  Cd Length: 80  Bit Score: 153.30  E-value: 8.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781    1 MLSMIVLLSLLWGAPSHAYFSCHTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDSQIITFGTDC 80
Cdd:pfam15981   1 MLSMIVLLFLLWGAPSHAYFSYYTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDEQIITFGTDC 80
Arteri_Gl pfam00951
Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and ...
 88-254 2.29e-41

Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and N. Gl envelope protein, is encoded in ORF5, and is 30- 45 kDa in size. Gl is heterogenously glycosylated with N-acetyllactosamine in a cell-type-specific manner. The Gl glycoprotein expresses the neutralization determinants.


:

Pssm-ID: 109986  Cd Length: 179  Bit Score: 139.90  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781   88 VAEVLEEEHGPYSALFDDMPPFIYYGREFGIVVLDVFMFYPVLVLFFLSVLPYATLILEMCVSVL----FIIYG-IYSGA 162
Cdd:pfam00951   7 VNGNSSTYQYIYNLTICELNGTGWLGTHFDWAVETFPLFPYLTHLFSLGLLTTAHFLDFLNLSALsytgYVHGRyVLSSA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781  163 YLAMGIFAATLAIHSIVVLRQLLWLCLAWRYRCTLHASFI-SAEGKVYPVDPGLpSAAVGNRLLVPGRPT-IDYAVAYGS 240
Cdd:pfam00951  87 YAACALAALVFGVYSFVIRAVRLRNCMAGRYACTRHTNFVdDARGRIHRSDSPV-VVRKPGKTLVGGDLVgIKTVVLGGR 165

                         170
                  ....*....|....
gi 392312781  241 KVNLVRLGAAEVWE 254
Cdd:pfam00951 166 KAVKLTRVSAEKWE 179
 
Name Accession Description Interval E-value
EAV_GP5 pfam15981
Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in ...
 1-80 8.02e-48

Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in equine arteritis virus envelope. It is approximately 80 amino acids in length and is found in association with pfam00951.


Pssm-ID: 292603  Cd Length: 80  Bit Score: 153.30  E-value: 8.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781    1 MLSMIVLLSLLWGAPSHAYFSCHTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDSQIITFGTDC 80
Cdd:pfam15981   1 MLSMIVLLFLLWGAPSHAYFSYYTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDEQIITFGTDC 80
Arteri_Gl pfam00951
Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and ...
 88-254 2.29e-41

Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and N. Gl envelope protein, is encoded in ORF5, and is 30- 45 kDa in size. Gl is heterogenously glycosylated with N-acetyllactosamine in a cell-type-specific manner. The Gl glycoprotein expresses the neutralization determinants.


Pssm-ID: 109986  Cd Length: 179  Bit Score: 139.90  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781   88 VAEVLEEEHGPYSALFDDMPPFIYYGREFGIVVLDVFMFYPVLVLFFLSVLPYATLILEMCVSVL----FIIYG-IYSGA 162
Cdd:pfam00951   7 VNGNSSTYQYIYNLTICELNGTGWLGTHFDWAVETFPLFPYLTHLFSLGLLTTAHFLDFLNLSALsytgYVHGRyVLSSA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781  163 YLAMGIFAATLAIHSIVVLRQLLWLCLAWRYRCTLHASFI-SAEGKVYPVDPGLpSAAVGNRLLVPGRPT-IDYAVAYGS 240
Cdd:pfam00951  87 YAACALAALVFGVYSFVIRAVRLRNCMAGRYACTRHTNFVdDARGRIHRSDSPV-VVRKPGKTLVGGDLVgIKTVVLGGR 165

                         170
                  ....*....|....
gi 392312781  241 KVNLVRLGAAEVWE 254
Cdd:pfam00951 166 KAVKLTRVSAEKWE 179
 
Name Accession Description Interval E-value
EAV_GP5 pfam15981
Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in ...
 1-80 8.02e-48

Envelope glycoprotein GP 5 of equine arteritis virus; EAV_GP5 is a domain family found in equine arteritis virus envelope. It is approximately 80 amino acids in length and is found in association with pfam00951.


Pssm-ID: 292603  Cd Length: 80  Bit Score: 153.30  E-value: 8.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781    1 MLSMIVLLSLLWGAPSHAYFSCHTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDSQIITFGTDC 80
Cdd:pfam15981   1 MLSMIVLLFLLWGAPSHAYFSYYTAQRFTDFTLCMLTDRGVIANLLRYDEHTALYNCSASKTCWYCTFLDEQIITFGTDC 80
Arteri_Gl pfam00951
Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and ...
 88-254 2.29e-41

Arterivirus GL envelope glycoprotein; Arteriviruses encode 4 envelope proteins, Gl, Gs, M and N. Gl envelope protein, is encoded in ORF5, and is 30- 45 kDa in size. Gl is heterogenously glycosylated with N-acetyllactosamine in a cell-type-specific manner. The Gl glycoprotein expresses the neutralization determinants.


Pssm-ID: 109986  Cd Length: 179  Bit Score: 139.90  E-value: 2.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781   88 VAEVLEEEHGPYSALFDDMPPFIYYGREFGIVVLDVFMFYPVLVLFFLSVLPYATLILEMCVSVL----FIIYG-IYSGA 162
Cdd:pfam00951   7 VNGNSSTYQYIYNLTICELNGTGWLGTHFDWAVETFPLFPYLTHLFSLGLLTTAHFLDFLNLSALsytgYVHGRyVLSSA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392312781  163 YLAMGIFAATLAIHSIVVLRQLLWLCLAWRYRCTLHASFI-SAEGKVYPVDPGLpSAAVGNRLLVPGRPT-IDYAVAYGS 240
Cdd:pfam00951  87 YAACALAALVFGVYSFVIRAVRLRNCMAGRYACTRHTNFVdDARGRIHRSDSPV-VVRKPGKTLVGGDLVgIKTVVLGGR 165

                         170
                  ....*....|....
gi 392312781  241 KVNLVRLGAAEVWE 254
Cdd:pfam00951 166 KAVKLTRVSAEKWE 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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