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Conserved domains on  [gi|389618424|gb|AFK92672|]
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fiber [Human adenovirus 39]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_knob super family cl08274
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 181-377 2.43e-52

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


The actual alignment was detected with superfamily member pfam00541:

Pssm-ID: 459847  Cd Length: 193  Bit Score: 172.70  E-value: 2.43e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  181 NRKDDRRTLWTTPDPSPNCKAETEKDSKLTLVLTKCGSQILATVSIIVLKGKYEFVKKETdpKSFDVKLLFDSKGVLLPT 260
Cdd:pfam00541   4 NKNDDKLTLWTTPDPSPNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTV--ASVSIFLRFDQNGVLMEN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  261 SNLSKEYWNYRSYDNNIGTPYENAVPFMPNLKAYPKptktasdkaeNKVSSAKNKIVSNFYFGGQTYQPGTIIIKFN--- 337
Cdd:pfam00541  82 SSLKKHYWNFRNGNSTNANPYTNAVGFMPNLLAYPK----------TQSQTAKNNIVSQVYLHGDKTKPMILTITLNgts 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 389618424  338 --EEIDDTCAYSITFNFGWGKTYDNPFPFDTTSFTFSYIAQE 377
Cdd:pfam00541 152 esTETSEVSTYSMSFTWSWESGKYTTETFATNSYTFSYIAQE 193
Adeno_shaft super family cl02909
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 33-74 1.01e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


The actual alignment was detected with superfamily member pfam00608:

Pssm-ID: 459865  Cd Length: 44  Bit Score: 36.52  E-value: 1.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 389618424   33 VSSDGFQNFPPGVLSLKLADPIAINNGNVSLKVGGGLTVEQD 74
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSS 42
Adeno_shaft super family cl02909
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 80-123 5.51e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


The actual alignment was detected with superfamily member pfam00608:

Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.60  E-value: 5.51e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 389618424   80 VNPKVPLQVANDKLELSYADPFETSANKLSLKVGHGLKVLDQKN 123
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSSGN 44
 
Name Accession Description Interval E-value
Adeno_knob pfam00541
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 181-377 2.43e-52

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


Pssm-ID: 459847  Cd Length: 193  Bit Score: 172.70  E-value: 2.43e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  181 NRKDDRRTLWTTPDPSPNCKAETEKDSKLTLVLTKCGSQILATVSIIVLKGKYEFVKKETdpKSFDVKLLFDSKGVLLPT 260
Cdd:pfam00541   4 NKNDDKLTLWTTPDPSPNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTV--ASVSIFLRFDQNGVLMEN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  261 SNLSKEYWNYRSYDNNIGTPYENAVPFMPNLKAYPKptktasdkaeNKVSSAKNKIVSNFYFGGQTYQPGTIIIKFN--- 337
Cdd:pfam00541  82 SSLKKHYWNFRNGNSTNANPYTNAVGFMPNLLAYPK----------TQSQTAKNNIVSQVYLHGDKTKPMILTITLNgts 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 389618424  338 --EEIDDTCAYSITFNFGWGKTYDNPFPFDTTSFTFSYIAQE 377
Cdd:pfam00541 152 esTETSEVSTYSMSFTWSWESGKYTTETFATNSYTFSYIAQE 193
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 33-74 1.01e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 36.52  E-value: 1.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 389618424   33 VSSDGFQNFPPGVLSLKLADPIAINNGNVSLKVGGGLTVEQD 74
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSS 42
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 80-123 5.51e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.60  E-value: 5.51e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 389618424   80 VNPKVPLQVANDKLELSYADPFETSANKLSLKVGHGLKVLDQKN 123
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSSGN 44
 
Name Accession Description Interval E-value
Adeno_knob pfam00541
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 181-377 2.43e-52

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


Pssm-ID: 459847  Cd Length: 193  Bit Score: 172.70  E-value: 2.43e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  181 NRKDDRRTLWTTPDPSPNCKAETEKDSKLTLVLTKCGSQILATVSIIVLKGKYEFVKKETdpKSFDVKLLFDSKGVLLPT 260
Cdd:pfam00541   4 NKNDDKLTLWTTPDPSPNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTV--ASVSIFLRFDQNGVLMEN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389618424  261 SNLSKEYWNYRSYDNNIGTPYENAVPFMPNLKAYPKptktasdkaeNKVSSAKNKIVSNFYFGGQTYQPGTIIIKFN--- 337
Cdd:pfam00541  82 SSLKKHYWNFRNGNSTNANPYTNAVGFMPNLLAYPK----------TQSQTAKNNIVSQVYLHGDKTKPMILTITLNgts 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 389618424  338 --EEIDDTCAYSITFNFGWGKTYDNPFPFDTTSFTFSYIAQE 377
Cdd:pfam00541 152 esTETSEVSTYSMSFTWSWESGKYTTETFATNSYTFSYIAQE 193
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 33-74 1.01e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 36.52  E-value: 1.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 389618424   33 VSSDGFQNFPPGVLSLKLADPIAINNGNVSLKVGGGLTVEQD 74
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSS 42
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 80-123 5.51e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.60  E-value: 5.51e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 389618424   80 VNPKVPLQVANDKLELSYADPFETSANKLSLKVGHGLKVLDQKN 123
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDSSGN 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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