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Conserved domains on  [gi|3859988|gb|AAC72944|]
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proteasome subunit p58 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rpn3_C pfam08375
Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of ...
 46-104 2.64e-27

Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of 26S proteasome regulatory subunits such as the non-ATPase Rpn3 subunit which is essential for proteasomal function. It occurs together with the PCI/PINT domain (pfam01399).


:

Pssm-ID: 462452  Cd Length: 57  Bit Score: 94.96  E-value: 2.64e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 3859988     46 DIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAeeRREREQQDLEFAK 104
Cdd:pfam08375   1 DVYSTNEPQEAFHQRIKFCLQLHNESVKAMRYPPDAHKKELESA--EEAREREERELAK 57
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 17-64 2.59e-07

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


:

Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 44.93  E-value: 2.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 3859988      17 SLLAKAIRDGVIEASINHEKGYVQSKEMIDIYStrEPQLAFHQRISFC 64
Cdd:smart00088  43 KLVSKAIRDGEISAKIDQVNGIVEFEEVDPRRS--EPLAQFAETLKKL 88
 
Name Accession Description Interval E-value
Rpn3_C pfam08375
Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of ...
 46-104 2.64e-27

Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of 26S proteasome regulatory subunits such as the non-ATPase Rpn3 subunit which is essential for proteasomal function. It occurs together with the PCI/PINT domain (pfam01399).


Pssm-ID: 462452  Cd Length: 57  Bit Score: 94.96  E-value: 2.64e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 3859988     46 DIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAeeRREREQQDLEFAK 104
Cdd:pfam08375   1 DVYSTNEPQEAFHQRIKFCLQLHNESVKAMRYPPDAHKKELESA--EEAREREERELAK 57
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 17-64 2.59e-07

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 44.93  E-value: 2.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 3859988      17 SLLAKAIRDGVIEASINHEKGYVQSKEMIDIYStrEPQLAFHQRISFC 64
Cdd:smart00088  43 KLVSKAIRDGEISAKIDQVNGIVEFEEVDPRRS--EPLAQFAETLKKL 88
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 17-43 6.14e-03

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 33.73  E-value: 6.14e-03
                          10        20
                  ....*....|....*....|....*..
gi 3859988     17 SLLAKAIRDGVIEASINHEKGYVQSKE 43
Cdd:pfam01399  79 KILAKLIRDGRIRAKIDQVNGIVVFSK 105
 
Name Accession Description Interval E-value
Rpn3_C pfam08375
Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of ...
 46-104 2.64e-27

Proteasome regulatory subunit C-terminal; This eukaryotic domain is found at the C-terminus of 26S proteasome regulatory subunits such as the non-ATPase Rpn3 subunit which is essential for proteasomal function. It occurs together with the PCI/PINT domain (pfam01399).


Pssm-ID: 462452  Cd Length: 57  Bit Score: 94.96  E-value: 2.64e-27
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 3859988     46 DIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAeeRREREQQDLEFAK 104
Cdd:pfam08375   1 DVYSTNEPQEAFHQRIKFCLQLHNESVKAMRYPPDAHKKELESA--EEAREREERELAK 57
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 17-64 2.59e-07

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 44.93  E-value: 2.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 3859988      17 SLLAKAIRDGVIEASINHEKGYVQSKEMIDIYStrEPQLAFHQRISFC 64
Cdd:smart00088  43 KLVSKAIRDGEISAKIDQVNGIVEFEEVDPRRS--EPLAQFAETLKKL 88
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 17-43 6.14e-03

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 33.73  E-value: 6.14e-03
                          10        20
                  ....*....|....*....|....*..
gi 3859988     17 SLLAKAIRDGVIEASINHEKGYVQSKE 43
Cdd:pfam01399  79 KILAKLIRDGRIRAKIDQVNGIVVFSK 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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