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Conserved domains on  [gi|38256957|dbj|BAD01541|]
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keratin associated protein [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 202-321 4.71e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 57.88  E-value: 4.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   202 SSCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTCSDD-SGSCCQPACCTSSQSQQGC--------------- 265
Cdd:pfam01500  18 GTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCcQTSCCQPTCCQTSSCQTGCggigygqegssgavs 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38256957   266 ----------CVPVCCKPVCCVPVCSgaSTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPAC 321
Cdd:pfam01500  98 srtrwcrpdcRVEGTCLPPCCVVSCT--PPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 46-243 4.05e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 4.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957    46 CCAPAPCLSLVCTPVSYVSSPCCRVTCEPSPCqsgctssCTPSCCQQSSCQLACCASSPCQ---QACCVPVCCKTVCCKP 122
Cdd:pfam01500   3 CCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSC-------CRPSCCQTSCCQPTTFQSSCCRptcQPCCQTSCCQPTCCQT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   123 VYCVPVCSGDSSCCQQSSCQSACCTSSpCQQACCVPICCKPVCSgisssccqqsscvscvsspccqavcepspcqsgCIS 202
Cdd:pfam01500  76 SSCQTGCGGIGYGQEGSSGAVSSRTRW-CRPDCRVEGTCLPPCC---------------------------------VVS 121

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 38256957   203 SCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPvCCVPTC 243
Cdd:pfam01500 122 CTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQ-CSEPTC 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
317-363 8.01e-04

Keratin, high sulfur B2 protein;


:

Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 36.98  E-value: 8.01e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 38256957   317 CRPACCVPVpscCAPTSSCQASCCRPASCVSLLCRPACSRPACCGPT 363
Cdd:pfam13885   2 CQPSCCQPS---CCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 202-321 4.71e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 57.88  E-value: 4.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   202 SSCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTCSDD-SGSCCQPACCTSSQSQQGC--------------- 265
Cdd:pfam01500  18 GTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCcQTSCCQPTCCQTSSCQTGCggigygqegssgavs 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38256957   266 ----------CVPVCCKPVCCVPVCSgaSTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPAC 321
Cdd:pfam01500  98 srtrwcrpdcRVEGTCLPPCCVVSCT--PPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 46-243 4.05e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 4.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957    46 CCAPAPCLSLVCTPVSYVSSPCCRVTCEPSPCqsgctssCTPSCCQQSSCQLACCASSPCQ---QACCVPVCCKTVCCKP 122
Cdd:pfam01500   3 CCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSC-------CRPSCCQTSCCQPTTFQSSCCRptcQPCCQTSCCQPTCCQT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   123 VYCVPVCSGDSSCCQQSSCQSACCTSSpCQQACCVPICCKPVCSgisssccqqsscvscvsspccqavcepspcqsgCIS 202
Cdd:pfam01500  76 SSCQTGCGGIGYGQEGSSGAVSSRTRW-CRPDCRVEGTCLPPCC---------------------------------VVS 121

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 38256957   203 SCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPvCCVPTC 243
Cdd:pfam01500 122 CTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQ-CSEPTC 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
317-363 8.01e-04

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 36.98  E-value: 8.01e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 38256957   317 CRPACCVPVpscCAPTSSCQASCCRPASCVSLLCRPACSRPACCGPT 363
Cdd:pfam13885   2 CQPSCCQPS---CCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 202-321 4.71e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 57.88  E-value: 4.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   202 SSCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTCSDD-SGSCCQPACCTSSQSQQGC--------------- 265
Cdd:pfam01500  18 GTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCcQTSCCQPTCCQTSSCQTGCggigygqegssgavs 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38256957   266 ----------CVPVCCKPVCCVPVCSgaSTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPAC 321
Cdd:pfam01500  98 srtrwcrpdcRVEGTCLPPCCVVSCT--PPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 207-359 1.63e-09

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 56.34  E-value: 1.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   207 SCCQQSSCK-PACCTSSPCQQACCVPVCCKPvccvptcsddsgSCCQPACCTSSQSQQGCCVPVCCKPVCcvpvcsgasT 285
Cdd:pfam01500   2 ACCGTSFCGfPTCSTGGTCGSGCCQPCCCQS------------SCCRPSCCQTSCCQPTTFQSSCCRPTC---------Q 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   286 SCCQQSSCQPACCTTSCCRPS---------------SSVSLLCRPVCR------PACCVP--VPSCCAPTSSCQASCCRP 342
Cdd:pfam01500  61 PCCQTSCCQPTCCQTSSCQTGcggigygqegssgavSSRTRWCRPDCRvegtclPPCCVVscTPPTCCQLHHAQASCCRP 140

                         170
                  ....*....|....*..
gi 38256957   343 ASCVSLLCRPACSRPAC 359
Cdd:pfam01500 141 SYCGQSCCRPACCCQCS 157
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
203-243 1.33e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 47.38  E-value: 1.33e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 38256957   203 SCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTC 243
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSC 41
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
202-242 1.53e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 47.38  E-value: 1.53e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 38256957   202 SSCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPT 242
Cdd:pfam13885   5 SCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 46-243 4.05e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.40  E-value: 4.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957    46 CCAPAPCLSLVCTPVSYVSSPCCRVTCEPSPCqsgctssCTPSCCQQSSCQLACCASSPCQ---QACCVPVCCKTVCCKP 122
Cdd:pfam01500   3 CCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSC-------CRPSCCQTSCCQPTTFQSSCCRptcQPCCQTSCCQPTCCQT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   123 VYCVPVCSGDSSCCQQSSCQSACCTSSpCQQACCVPICCKPVCSgisssccqqsscvscvsspccqavcepspcqsgCIS 202
Cdd:pfam01500  76 SSCQTGCGGIGYGQEGSSGAVSSRTRW-CRPDCRVEGTCLPPCC---------------------------------VVS 121

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 38256957   203 SCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPvCCVPTC 243
Cdd:pfam01500 122 CTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQ-CSEPTC 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
84-128 4.23e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 46.22  E-value: 4.23e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 38256957    84 SCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVYCVPV 128
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
82-123 4.67e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 45.84  E-value: 4.67e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 38256957    82 TSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPV 123
Cdd:pfam13885   4 PSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 35-165 4.80e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.02  E-value: 4.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957    35 DDCPESCCEPPCCAPAPCLSLVCTPVSYVSSpCCRVTCEPSpCQSGCtssCTPSCCQQSSCQLACCASSPCQQACCVPVC 114
Cdd:pfam01500  23 GCCQPCCCQSSCCRPSCCQTSCCQPTTFQSS-CCRPTCQPC-CQTSC---CQPTCCQTSSCQTGCGGIGYGQEGSSGAVS 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 38256957   115 CKTVCCKPVYCVPVCSGDSSCCQQSSCQSACCT----SSPCQQACCVPICCKPVC 165
Cdd:pfam01500  98 SRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLhhaqASCCRPSYCGQSCCRPAC 152
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
265-316 1.31e-06

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 44.68  E-value: 1.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 38256957   265 CCVPVCCKPVCCVPvcsgastSCCQQSSCQPACCTTSCCRPSSSVSLLCRPV 316
Cdd:pfam13885   1 CCQPSCCQPSCCQP-------SCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
89-129 1.31e-06

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 44.68  E-value: 1.31e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 38256957    89 CCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVYCVPVC 129
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSC 41
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 114-280 2.07e-06

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 47.48  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   114 CCKTVCCKPVYCVPVCSGDSSCCQQSSCQSACCTSSPCQQACCVPICCKPVCsgissscCQQSSCVSCVSSPCCQAVCEP 193
Cdd:pfam01500   3 CCGTSFCGFPTCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSC-------CRPTCQPCCQTSCCQPTCCQT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   194 SPCQSGCissCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPtcsddsgSCCQPACCTSSQSQQGCCVPVCCKP 273
Cdd:pfam01500  76 SSCQTGC---GGIGYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVV-------SCTPPTCCQLHHAQASCCRPSYCGQ 145


                  ....*..
gi 38256957   274 VCCVPVC 280
Cdd:pfam01500 146 SCCRPAC 152
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 270-370 8.77e-06

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 45.55  E-value: 8.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   270 CCKPVCCVPVCSGASTscCQQSSCQPACCTTSCCRPSSSVSLLCRPVC-RPACCVPVPSCCAPTSSCQASCCRPASCVSL 348
Cdd:pfam01500   4 CGTSFCGFPTCSTGGT--CGSGCCQPCCCQSSCCRPSCCQTSCCQPTTfQSSCCRPTCQPCCQTSCCQPTCCQTSSCQTG 81

                          90       100
                  ....*....|....*....|..
gi 38256957   349 LCRPACSRPACCGPTSTQKSSC 370
Cdd:pfam01500  82 CGGIGYGQEGSSGAVSSRTRWC 103
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
228-280 9.32e-06

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 42.37  E-value: 9.32e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 38256957   228 CCVPVCCKPVCCVPtcsddsgSCCQPACCTSSqsqqgCCVPVCCKPVCCVPVC 280
Cdd:pfam13885   1 CCQPSCCQPSCCQP-------SCCQPSCCQPS-----CCQPSCCRPSCCRSSC 41
PMG pfam05287
PMG protein; This family consists of several mouse anagen-specific protein mKAP13 (PMG1 and ...
 2-160 2.76e-04

PMG protein; This family consists of several mouse anagen-specific protein mKAP13 (PMG1 and PMG2). PMG1 and 2 contain characteriztic repeats reminiscent of the keratin-associated proteins (KAPs). Both genes are expressed in growing hair follicles in skin as well as in sebaceous and eccrine sweat glands. Interestingly, expression is also detected in the mammary epithelium where it is limited to the onset of the pubertal growth phase and is independent of ovarian hormones. Their broad, developmentally controlled expression pattern, together with their unique amino acid composition, demonstrate that pmg-1 and pmg-2 constitute a novel KAP gene family participating in the differentiation of all epithelial cells forming the epidermal appendages.


Pssm-ID: 283053 [Multi-domain]  Cd Length: 180  Bit Score: 41.34  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957     2 AASTMSVCSSDLSYGSRVCLPGSCDScsDSWQVDDCPESCCEPPCCAPAPCLSLVCTPVSYVSSPCCRVTCEPSpcQSGC 81
Cdd:pfam05287  23 VSSCGSSCPSNLSYSTDLCSPSSCQL--GSSLRDNCQETCGEPTSCQTSSCEPCTSSTSYCVPSPCQRSCYSPR--TSCV 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38256957    82 TSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCCKPVYCVpVCSGDSSCCQQSSCQSACCTSSPCQQACCVPIC 160
Cdd:pfam05287  99 CSPCQTTSAGSLGFGSSSCQSLGYGSNSCQPLGCGSSGFRPLGCL-SKGFQSLGYGSSFCRPSYVSSRSYQPSCFRPSC 176
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
317-363 8.01e-04

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 36.98  E-value: 8.01e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 38256957   317 CRPACCVPVpscCAPTSSCQASCCRPASCVSLLCRPACSRPACCGPT 363
Cdd:pfam13885   2 CQPSCCQPS---CCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
PMG pfam05287
PMG protein; This family consists of several mouse anagen-specific protein mKAP13 (PMG1 and ...
 203-359 9.21e-04

PMG protein; This family consists of several mouse anagen-specific protein mKAP13 (PMG1 and PMG2). PMG1 and 2 contain characteriztic repeats reminiscent of the keratin-associated proteins (KAPs). Both genes are expressed in growing hair follicles in skin as well as in sebaceous and eccrine sweat glands. Interestingly, expression is also detected in the mammary epithelium where it is limited to the onset of the pubertal growth phase and is independent of ovarian hormones. Their broad, developmentally controlled expression pattern, together with their unique amino acid composition, demonstrate that pmg-1 and pmg-2 constitute a novel KAP gene family participating in the differentiation of all epithelial cells forming the epidermal appendages.


Pssm-ID: 283053 [Multi-domain]  Cd Length: 180  Bit Score: 39.80  E-value: 9.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38256957   203 SCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTCSDDSGsCCQPACCTSSQSQQGCCVPVCCKPVCCVPVCSG 282
Cdd:pfam05287  35 SYSTDLCSPSSCQLGSSLRDNCQETCGEPTSCQTSSCEPCTSSTSY-CVPSPCQRSCYSPRTSCVCSPCQTTSAGSLGFG 113

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 38256957   283 AStsccqqsSCQPACCTTSCCRPSSSVSLLCRPVcrpaccvPVPSCCAPTSSCQASCCRPASCVSLLCRPACSRPAC 359
Cdd:pfam05287 114 SS-------SCQSLGYGSNSCQPLGCGSSGFRPL-------GCLSKGFQSLGYGSSFCRPSYVSSRSYQPSCFRPSC 176
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
284-325 1.13e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 36.59  E-value: 1.13e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 38256957   284 STSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVC-RPACCVPV 325
Cdd:pfam13885   3 QPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCcRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
326-366 4.63e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 34.67  E-value: 4.63e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 38256957   326 PSCCAPtSSCQASCCRPASCVSLLCRPACSRPACCGPTSTQ 366
Cdd:pfam13885   4 PSCCQP-SCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQ 43
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
104-165 8.88e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 33.89  E-value: 8.88e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 38256957   104 PCQQACCVPVCCKTVCCKPVYCVPVCsgdssccqqsscqsacctsspCQQACCVPICCKPVC 165
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSC---------------------CQPSCCRPSCCRSSC 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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