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Conserved domains on  [gi|380092651|emb|CCC09928|]
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unnamed protein product [Sordaria macrospora k-hell]

Protein Classification

HET domain-containing protein( domain architecture ID 3637)

heterokaryon incompatibility (HET) domain-containing protein is involved in determining vegetative incompatibility in fungi

PubMed:  12620257

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HET super family cl06163
Heterokaryon incompatibility protein (HET); This family represents a conserved region ...
 197-356 1.91e-23

Heterokaryon incompatibility protein (HET); This family represents a conserved region approximately 150 residues long within various heterokaryon incompatibility proteins that seem to be restricted to ascomycete fungi. Genetic differences in specific het genes prevent a viable heterokaryotic fungal cell from being formed by the fusion of filaments from two different wild-type strains. Many family members also contain the pfam00400 repeat and the pfam05729 domain.


The actual alignment was detected with superfamily member pfam06985:

Pssm-ID: 369159  Cd Length: 146  Bit Score: 96.67  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  197 YGTVTHRWGftvedkERVILTQATYPMLAKGILLSSMPRLFQDIITFAYQLGLRYMWIDAFCIFQDnNNNDWQRESSLMQ 276
Cdd:pfam06985   1 YVALSYVWG------DPESLTSLRTQSIPINGRTLPLPRTLEDALRVLRRLGYRYLWIDALCINQD-DDKEKNQQVQLMG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  277 KVYTNSYCNISAADAISWSESLVNPRNTGLIASPVIELKRSREDGTPVPAPQqylvfdpTFWKREVTEALVNTRGWVLQE 356
Cdd:pfam06985  74 DIYSNAALVIVALGGEDADSGLPAVRSLRRLAQLSVRVDDRISSDLSLLLRS-------WRALEDLLESPWFTRGWTLQE 146
 
Name Accession Description Interval E-value
HET pfam06985
Heterokaryon incompatibility protein (HET); This family represents a conserved region ...
 197-356 1.91e-23

Heterokaryon incompatibility protein (HET); This family represents a conserved region approximately 150 residues long within various heterokaryon incompatibility proteins that seem to be restricted to ascomycete fungi. Genetic differences in specific het genes prevent a viable heterokaryotic fungal cell from being formed by the fusion of filaments from two different wild-type strains. Many family members also contain the pfam00400 repeat and the pfam05729 domain.


Pssm-ID: 369159  Cd Length: 146  Bit Score: 96.67  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  197 YGTVTHRWGftvedkERVILTQATYPMLAKGILLSSMPRLFQDIITFAYQLGLRYMWIDAFCIFQDnNNNDWQRESSLMQ 276
Cdd:pfam06985   1 YVALSYVWG------DPESLTSLRTQSIPINGRTLPLPRTLEDALRVLRRLGYRYLWIDALCINQD-DDKEKNQQVQLMG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  277 KVYTNSYCNISAADAISWSESLVNPRNTGLIASPVIELKRSREDGTPVPAPQqylvfdpTFWKREVTEALVNTRGWVLQE 356
Cdd:pfam06985  74 DIYSNAALVIVALGGEDADSGLPAVRSLRRLAQLSVRVDDRISSDLSLLLRS-------WRALEDLLESPWFTRGWTLQE 146
 
Name Accession Description Interval E-value
HET pfam06985
Heterokaryon incompatibility protein (HET); This family represents a conserved region ...
 197-356 1.91e-23

Heterokaryon incompatibility protein (HET); This family represents a conserved region approximately 150 residues long within various heterokaryon incompatibility proteins that seem to be restricted to ascomycete fungi. Genetic differences in specific het genes prevent a viable heterokaryotic fungal cell from being formed by the fusion of filaments from two different wild-type strains. Many family members also contain the pfam00400 repeat and the pfam05729 domain.


Pssm-ID: 369159  Cd Length: 146  Bit Score: 96.67  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  197 YGTVTHRWGftvedkERVILTQATYPMLAKGILLSSMPRLFQDIITFAYQLGLRYMWIDAFCIFQDnNNNDWQRESSLMQ 276
Cdd:pfam06985   1 YVALSYVWG------DPESLTSLRTQSIPINGRTLPLPRTLEDALRVLRRLGYRYLWIDALCINQD-DDKEKNQQVQLMG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 380092651  277 KVYTNSYCNISAADAISWSESLVNPRNTGLIASPVIELKRSREDGTPVPAPQqylvfdpTFWKREVTEALVNTRGWVLQE 356
Cdd:pfam06985  74 DIYSNAALVIVALGGEDADSGLPAVRSLRRLAQLSVRVDDRISSDLSLLLRS-------WRALEDLLESPWFTRGWTLQE 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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