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Conserved domains on  [gi|379977187|gb|AFD22023|]
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fiber 1 [Simian adenovirus A1285]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_knob super family cl08274
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 373-536 3.79e-21

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


The actual alignment was detected with superfamily member pfam00541:

Pssm-ID: 459847  Cd Length: 193  Bit Score: 91.42  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  373 LSLWSHPIRA-NCTVYEPLDAQLALCLSKCGAHVLGTVSLQPLSGQLATAMPT-ESLTLQLLFDEQGALLHTGPLEPTAW 450
Cdd:pfam00541  10 LTLWTTPDPSpNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTvASVSIFLRFDQNGVLMENSSLKKHYW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  451 GYREDNALSPDPVTHALEFMPSALAYPR----AADPPHFSAQFL--PSSPPVTFSVAYN--------SAPSGFALSLTWS 516
Cdd:pfam00541  90 NFRNGNSTNANPYTNAVGFMPNLLAYPKtqsqTAKNNIVSQVYLhgDKTKPMILTITLNgtsestetSEVSTYSMSFTWS 169

                         170       180
                  ....*....|....*....|....
gi 379977187  517 ATPG----QPFSAPLATFAYVSEQ 536
Cdd:pfam00541 170 WESGkyttETFATNSYTFSYIAQE 193
Sarcoglycan_1 super family cl20274
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 244-388 1.69e-03

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


The actual alignment was detected with superfamily member pfam04790:

Pssm-ID: 461428  Cd Length: 255  Bit Score: 40.29  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  244 SQLVVKaGGGIAFDSSGGLRINAAggmrvnDSNTLILHVAYPfeatnQLTIRLGPGLNVNTNHQLQVN-----SGPGLTF 318
Cdd:pfam04790 100 SQLVVG-PDGAVEASVNRFEVKDP------DGGKTLFSADRP-----EVTVGADKGKKLRVTGSVETPrirspPDEDLRL 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 379977187  319 SNNALQVSVDTSKGLQYATTGSSISVKVGAGLRFDS-NGAIALNSTARSLPDLRPLSLWSHPIRANCTVYE 388
Cdd:pfam04790 168 ESPTRSLSLRAPEGVHIEARAGNISATSLKDIKLRStNGSIVLDASGIFLPNLRPVSSSSGSSQTVSTQYK 238
Adeno_shaft super family cl02909
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 96-136 5.23e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


The actual alignment was detected with superfamily member pfam00608:

Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.98  E-value: 5.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 379977187   96 LNSSPPLTVSAGSLTLAQSEPLTVTSNALTLAYSSPLAVSS 136
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDS 41
 
Name Accession Description Interval E-value
Adeno_knob pfam00541
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 373-536 3.79e-21

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


Pssm-ID: 459847  Cd Length: 193  Bit Score: 91.42  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  373 LSLWSHPIRA-NCTVYEPLDAQLALCLSKCGAHVLGTVSLQPLSGQLATAMPT-ESLTLQLLFDEQGALLHTGPLEPTAW 450
Cdd:pfam00541  10 LTLWTTPDPSpNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTvASVSIFLRFDQNGVLMENSSLKKHYW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  451 GYREDNALSPDPVTHALEFMPSALAYPR----AADPPHFSAQFL--PSSPPVTFSVAYN--------SAPSGFALSLTWS 516
Cdd:pfam00541  90 NFRNGNSTNANPYTNAVGFMPNLLAYPKtqsqTAKNNIVSQVYLhgDKTKPMILTITLNgtsestetSEVSTYSMSFTWS 169

                         170       180
                  ....*....|....*....|....
gi 379977187  517 ATPG----QPFSAPLATFAYVSEQ 536
Cdd:pfam00541 170 WESGkyttETFATNSYTFSYIAQE 193
Sarcoglycan_1 pfam04790
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 244-388 1.69e-03

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


Pssm-ID: 461428  Cd Length: 255  Bit Score: 40.29  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  244 SQLVVKaGGGIAFDSSGGLRINAAggmrvnDSNTLILHVAYPfeatnQLTIRLGPGLNVNTNHQLQVN-----SGPGLTF 318
Cdd:pfam04790 100 SQLVVG-PDGAVEASVNRFEVKDP------DGGKTLFSADRP-----EVTVGADKGKKLRVTGSVETPrirspPDEDLRL 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 379977187  319 SNNALQVSVDTSKGLQYATTGSSISVKVGAGLRFDS-NGAIALNSTARSLPDLRPLSLWSHPIRANCTVYE 388
Cdd:pfam04790 168 ESPTRSLSLRAPEGVHIEARAGNISATSLKDIKLRStNGSIVLDASGIFLPNLRPVSSSSGSSQTVSTQYK 238
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 96-136 5.23e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.98  E-value: 5.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 379977187   96 LNSSPPLTVSAGSLTLAQSEPLTVTSNALTLAYSSPLAVSS 136
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDS 41
 
Name Accession Description Interval E-value
Adeno_knob pfam00541
Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through ...
 373-536 3.79e-21

Adenoviral fibre protein (knob domain); Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, termed the carboxy-terminal knob domain.


Pssm-ID: 459847  Cd Length: 193  Bit Score: 91.42  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  373 LSLWSHPIRA-NCTVYEPLDAQLALCLSKCGAHVLGTVSLQPLSGQLATAMPT-ESLTLQLLFDEQGALLHTGPLEPTAW 450
Cdd:pfam00541  10 LTLWTTPDPSpNCRIHSDNDCKFTLVLTKCGSQVLATVAALAVSGDLSSMTGTvASVSIFLRFDQNGVLMENSSLKKHYW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  451 GYREDNALSPDPVTHALEFMPSALAYPR----AADPPHFSAQFL--PSSPPVTFSVAYN--------SAPSGFALSLTWS 516
Cdd:pfam00541  90 NFRNGNSTNANPYTNAVGFMPNLLAYPKtqsqTAKNNIVSQVYLhgDKTKPMILTITLNgtsestetSEVSTYSMSFTWS 169

                         170       180
                  ....*....|....*....|....
gi 379977187  517 ATPG----QPFSAPLATFAYVSEQ 536
Cdd:pfam00541 170 WESGkyttETFATNSYTFSYIAQE 193
Sarcoglycan_1 pfam04790
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 244-388 1.69e-03

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


Pssm-ID: 461428  Cd Length: 255  Bit Score: 40.29  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 379977187  244 SQLVVKaGGGIAFDSSGGLRINAAggmrvnDSNTLILHVAYPfeatnQLTIRLGPGLNVNTNHQLQVN-----SGPGLTF 318
Cdd:pfam04790 100 SQLVVG-PDGAVEASVNRFEVKDP------DGGKTLFSADRP-----EVTVGADKGKKLRVTGSVETPrirspPDEDLRL 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 379977187  319 SNNALQVSVDTSKGLQYATTGSSISVKVGAGLRFDS-NGAIALNSTARSLPDLRPLSLWSHPIRANCTVYE 388
Cdd:pfam04790 168 ESPTRSLSLRAPEGVHIEARAGNISATSLKDIKLRStNGSIVLDASGIFLPNLRPVSSSSGSSQTVSTQYK 238
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 96-136 5.23e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.98  E-value: 5.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 379977187   96 LNSSPPLTVSAGSLTLAQSEPLTVTSNALTLAYSSPLAVSS 136
Cdd:pfam00608   1 ISTNAPLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDS 41
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 114-152 5.60e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.98  E-value: 5.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 379977187  114 SEPLTVTSNALTLAYSSPLAVSSGALTLtNPSQPLTLSS 152
Cdd:pfam00608   4 NAPLKVNDSNLSLKTGPPLTVSNGALRL-KLGAPLTVDS 41
Adeno_shaft pfam00608
Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and ...
 85-121 7.24e-03

Adenoviral fibre protein (repeat/shaft region); There is no separation between signal and noise. Specific attachment of adenovirus is achieved through interactions between host-cell receptors and the adenovirus fibre protein and is mediated by the globular carboxy-terminal domain of the adenovirus fibre protein, rather than the 'shaft' region represented by this family. The alignment of this family contains two copies of a fifteen residue repeat found in the 'shaft' region of adenoviral fibre proteins.


Pssm-ID: 459865  Cd Length: 44  Bit Score: 34.60  E-value: 7.24e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 379977187   85 APLTSTQGTIGLNSSPPLTVSAGSLTLAQSEPLTVTS 121
Cdd:pfam00608   5 APLKVNDSNLSLKTGPPLTVSNGALRLKLGAPLTVDS 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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