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Conserved domains on  [gi|37926703|gb|AAO46634|]
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non-structural protein NS2 [Influenza A virus (A/Poland/5/67(H2N2))]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Flu_NS2 super family cl08276
Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of ...
 28-121 6.51e-38

Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of the genomic RNAs by preventing the replication of short-length RNA species.


The actual alignment was detected with superfamily member pfam00601:

Pssm-ID: 278996  Cd Length: 108  Bit Score: 123.82  E-value: 6.51e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37926703    28 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVR------------HRLKTTENSF- 94
Cdd:pfam00601   1 LKDIISQFEQLKLRRDSLGEAVMKMGDLHSLQNRNEKWREQLGQKFEEIRLAIEELRllskriddsilfHKLKIAENSFi 80

                          90       100
                  ....*....|....*....|....*...
gi 37926703    95 -EQITFMQALQLLFEVEQEIRTFSFQLI 121
Cdd:pfam00601  81 aDMITFLQALELLLEMEDEIETFSFQCI 108
 
Name Accession Description Interval E-value
Flu_NS2 pfam00601
Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of ...
 28-121 6.51e-38

Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of the genomic RNAs by preventing the replication of short-length RNA species.


Pssm-ID: 278996  Cd Length: 108  Bit Score: 123.82  E-value: 6.51e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37926703    28 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVR------------HRLKTTENSF- 94
Cdd:pfam00601   1 LKDIISQFEQLKLRRDSLGEAVMKMGDLHSLQNRNEKWREQLGQKFEEIRLAIEELRllskriddsilfHKLKIAENSFi 80

                          90       100
                  ....*....|....*....|....*...
gi 37926703    95 -EQITFMQALQLLFEVEQEIRTFSFQLI 121
Cdd:pfam00601  81 aDMITFLQALELLLEMEDEIETFSFQCI 108
 
Name Accession Description Interval E-value
Flu_NS2 pfam00601
Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of ...
 28-121 6.51e-38

Influenza non-structural protein (NS2); NS2 may play a role in promoting normal replication of the genomic RNAs by preventing the replication of short-length RNA species.


Pssm-ID: 278996  Cd Length: 108  Bit Score: 123.82  E-value: 6.51e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37926703    28 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVR------------HRLKTTENSF- 94
Cdd:pfam00601   1 LKDIISQFEQLKLRRDSLGEAVMKMGDLHSLQNRNEKWREQLGQKFEEIRLAIEELRllskriddsilfHKLKIAENSFi 80

                          90       100
                  ....*....|....*....|....*...
gi 37926703    95 -EQITFMQALQLLFEVEQEIRTFSFQLI 121
Cdd:pfam00601  81 aDMITFLQALELLLEMEDEIETFSFQCI 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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