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Conserved domains on  [gi|37693510|ref|NP_937767|]
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bone marrow stromal antigen 2 [Rattus norvegicus]

Protein Classification

BST2 domain-containing protein( domain architecture ID 11245197)

BST2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BST2 pfam16716
Bone marrow stromal antigen 2;
54-143 3.08e-39

Bone marrow stromal antigen 2;


:

Pssm-ID: 465245 [Multi-domain]  Cd Length: 91  Bit Score: 128.71  E-value: 3.08e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37693510    54 HSEACKNGLRLQDECRNTTHLLKHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQ 133
Cdd:pfam16716   1 NSEACKDGLRAEQECRNVTHLLQRQLTQAQDGLLQAEAQAATCNQTVVTLKASLEKEKAQGQKQQARVQELQGEIKTLNQ 80

                          90
                  ....*....|
gi 37693510   134 ELENLRTQKE 143
Cdd:pfam16716  81 QLQDALAEVE 90
 
Name Accession Description Interval E-value
BST2 pfam16716
Bone marrow stromal antigen 2;
54-143 3.08e-39

Bone marrow stromal antigen 2;


Pssm-ID: 465245 [Multi-domain]  Cd Length: 91  Bit Score: 128.71  E-value: 3.08e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37693510    54 HSEACKNGLRLQDECRNTTHLLKHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQ 133
Cdd:pfam16716   1 NSEACKDGLRAEQECRNVTHLLQRQLTQAQDGLLQAEAQAATCNQTVVTLKASLEKEKAQGQKQQARVQELQGEIKTLNQ 80

                          90
                  ....*....|
gi 37693510   134 ELENLRTQKE 143
Cdd:pfam16716  81 QLQDALAEVE 90
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 78-141 2.51e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 37.50  E-value: 2.51e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 37693510  78 QLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQELENLRTQ 141
Cdd:COG3883  17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE 80
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 76-143 4.16e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 36.92  E-value: 4.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37693510    76 KHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLN-------QELENLRTQKE 143
Cdd:TIGR04523 320 EKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKkenqsykQEIKNLESQIN 394
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 75-141 4.25e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 36.53  E-value: 4.25e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37693510     75 LKHQLtraqDSLLQTEMQANSCNQTVMD-LRDSLKK-------KVSQTQEQQARIKELENKIERLNQELENLRTQ 141
Cdd:smart00787 184 LEEEL----RQLKQLEDELEDCDPTELDrAKEKLKKllqeimiKVKKLEELEEELQELESKIEDLTNKKSELNTE 254
 
Name Accession Description Interval E-value
BST2 pfam16716
Bone marrow stromal antigen 2;
54-143 3.08e-39

Bone marrow stromal antigen 2;


Pssm-ID: 465245 [Multi-domain]  Cd Length: 91  Bit Score: 128.71  E-value: 3.08e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37693510    54 HSEACKNGLRLQDECRNTTHLLKHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQ 133
Cdd:pfam16716   1 NSEACKDGLRAEQECRNVTHLLQRQLTQAQDGLLQAEAQAATCNQTVVTLKASLEKEKAQGQKQQARVQELQGEIKTLNQ 80

                          90
                  ....*....|
gi 37693510   134 ELENLRTQKE 143
Cdd:pfam16716  81 QLQDALAEVE 90
Cluap1 pfam10234
Clusterin-associated protein-1; This protein is conserved from worms to humans. The protein of ...
 78-146 1.08e-03

Clusterin-associated protein-1; This protein is conserved from worms to humans. The protein of 413 amino acids contains a central coiled-coil domain, possibly the region that binds to clusterin. Cluap1 expression is highest in the nucleus and gradually increases during late S to G2/M phases of the cell cycle and returns to the basal level in the G0/G1 phases. In addition, it is upregulated in colon cancer tissues compared to corresponding non-cancerous mucosa. It thus plays a crucial role in the life of the cell.


Pssm-ID: 463013 [Multi-domain]  Cd Length: 268  Bit Score: 38.33  E-value: 1.08e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 37693510    78 QLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARI----KELENKIERLNQELEnlRTQKEIST 146
Cdd:pfam10234 148 DLREIRQQALSRPLEIAEIEKALKEAIKNVAAEIEQTQKQLENLasdeANLEAKIEKKKQELE--RNQKRLQT 218
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 78-141 2.51e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 37.50  E-value: 2.51e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 37693510  78 QLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQELENLRTQ 141
Cdd:COG3883  17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE 80
FapA pfam03961
Flagellar Assembly Protein A beta solenoid domain; This entry represents the C-terminal beta ...
 75-147 2.57e-03

Flagellar Assembly Protein A beta solenoid domain; This entry represents the C-terminal beta solenoid domain of FapA and its homologs. Members of this family include FapA (flagellar assembly protein A) found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction. This entry shows similarity to pfam03775 suggesting a similar functional role.


Pssm-ID: 461111 [Multi-domain]  Cd Length: 272  Bit Score: 37.28  E-value: 2.57e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 37693510    75 LKHQLTRAQDSLLQTE-----MQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQELENLRTQKEISTT 147
Cdd:pfam03961 161 LEKELEELEEELEKLKkrlkkLPKKARGQLPPEKREQLEKLLETKNKLSEELEELEEELKELKEELESLLGEGKISVN 238
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 76-143 4.16e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 36.92  E-value: 4.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37693510    76 KHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLN-------QELENLRTQKE 143
Cdd:TIGR04523 320 EKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKkenqsykQEIKNLESQIN 394
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 75-141 4.25e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 36.53  E-value: 4.25e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37693510     75 LKHQLtraqDSLLQTEMQANSCNQTVMD-LRDSLKK-------KVSQTQEQQARIKELENKIERLNQELENLRTQ 141
Cdd:smart00787 184 LEEEL----RQLKQLEDELEDCDPTELDrAKEKLKKllqeimiKVKKLEELEEELQELESKIEDLTNKKSELNTE 254
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 75-143 7.54e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 36.15  E-value: 7.54e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 37693510    75 LKHQLTRAQDSLLQTEMQANSCNQTVMDLRDS-------LKKKVSQTQEQQARIKELENKIERLNQELENLRTQKE 143
Cdd:TIGR04523 230 LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEqnkikkqLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE 305
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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