|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2793-3404 |
2.28e-28 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 128.34 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2793 ETSPPQEARQTRESSVSKQESNWDITKKRETRKTHQEAPKTKIPEKRARRGSEYSKEKLQKEKIKINMEQQKQVFETKDE 2872
Cdd:PTZ00121 1192 ELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAA 1271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2873 IVVEDTSKINVKNNEVEIKKEKVEDVQPEKRVDVEKTKKI-EAQKQDE-KQEIQEEKHDVQQRSRSQEKKRKGKKKKPEk 2950
Cdd:PTZ00121 1272 IKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAAEAAKA- 1350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2951 smddEIDKALKEIEDMDKQKKRD--KSREQTKIKDTTQTVQTEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAmnQ 3028
Cdd:PTZ00121 1351 ----EAEAAADEAEAAEEKAEAAekKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA--K 1424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3029 ANAKEQMKSKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIKiDSSSEMRKIETKEEKAQ--KDSANLSK 3106
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEeaKKKADEAK 1503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3107 KKQKGKEQTGTVK---DKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKS 3183
Cdd:PTZ00121 1504 KAAEAKKKADEAKkaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA 1583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3184 EKISetKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKqsQQKEEKKTEQSKQKKSVEKSEVIDIKLEEnEK 3263
Cdd:PTZ00121 1584 EEAK--KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK--AEEEKKKVEQLKKKEAEEKKKAEELKKAE-EE 1658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3264 IKIEIDVKAPKDEKEKKitgKEKEKKSESKDRKKKdikpEVALKEKAKEEQKAiinplinaiESDKKIEEKEIDN----- 3338
Cdd:PTZ00121 1659 NKIKAAEEAKKAEEDKK---KAEEAKKAEEDEKKA----AEALKKEAEEAKKA---------EELKKKEAEEKKKaeelk 1722
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 373194212 3339 KDSKESSTPKKEMKKAGEAEKQIKTKGGKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEK 3404
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
|
|
| KASH |
pfam10541 |
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS ... |
11199-11256 |
1.06e-27 |
|
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS domain is a highly hydrophobic nuclear envelope localization domain of approximately 60 amino acids comprising a 20-amino-acid transmembrane region and a 30-35-residue C-terminal region that lies between the inner and the outer nuclear membranes. During meiotic prophase, telomeres cluster to form a bouquet arrangement of chromosomes. SUN and KASH domain proteins form complexes that span both membranes of the nuclear envelope. The KASH domain links the dynein motor complex of the microtubules, through the outer nuclear membrane to the Sad1 domain in the inner nuclear membrane which then interacts with the bouquet proteins Bqt1 and Bqt2 that are complexed with Bqt4, Rap1 and Taz1 and attached to the telomere. SUN domain-containing proteins are essential for recruiting KASH domain proteins at the outer nuclear membrane, and KASH domains provide a generic NE tethering device for functionally distinct proteins whose cytoplasmic domains mediate nuclear positioning, maintain physical connections with other cellular organelles, and possibly even influence chromosome dynamics.
Pssm-ID: 463142 Cd Length: 58 Bit Score: 109.22 E-value: 1.06e-27
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 11199 FLGRVLRVSLPIQALMLLFLGVASLVPSAEEDYSCMLSNNLARSFTPMVVYPNGPPPI 11256
Cdd:pfam10541 1 FLGRVLRAALPLQLLLLLLLLLACLLPAGEEDYSCTLANNFARSFHPMLRYVNGPPPT 58
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
850-1062 |
1.16e-14 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 77.10 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 850 RKFEADLERARSWIKSKSNNLKklSGYLPLKASKVEQDIVQHGELETDIDSFSEKdLNDILKQGNNLLKECSEeDRARLN 929
Cdd:cd00176 3 QQFLRDADELEAWLSEKEELLS--STDYGDDLESVEALLKKHEALEAELAAHEER-VEALNELGEQLIEEGHP-DAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 930 KILDELNKDYEELKSEAQEKQAALADLLQGRKAFEsEIDKCQRWINEAEVATSSDVRTSSIDILREQLAKYDRLKKEANE 1009
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 1010 YADDIEKLMQQGKSILPTVTDADKLELNEQLQNMKEAHGRVAGIINERALALQ 1062
Cdd:cd00176 158 HEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLE 210
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
5604-6485 |
7.38e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.57 E-value: 7.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5604 KHEFKDKEQDKQIDNA--QTTEVELKLKDEITKESEIKDQEEAKENISEIKSKEIQEKSNENIFDNESELLQETKSDKSM 5681
Cdd:PTZ00121 1073 KPSYKDFDFDAKEDNRadEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5682 QSEKRKKKSKERKVEIAPKQvietfiEENKVLESEIQKEILKEQSEAKDIQDIKATTELVQETIYEKPTSSGKRKGKSKE 5761
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKA------EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA 1226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5762 KKKAITTEIAIKEKEVSRPEikEILKKESDIEEIKEIEEIEEKLKTIMKSEDEYKSEIVQETKS-KKSEFSEKNKEKSKE 5840
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKA 1304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5841 EEITKISIEKKKLPELKIKENTAEISLEQIIEISIEKNKPEIKGKISEKELEIEEDKEIQKEVQTSIKCEIENKPEVVQE 5920
Cdd:PTZ00121 1305 DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5921 TKFEKSPKKRKGKSKETKIETISEQITKISIDEKKLSEFEAKEEISSQIKEEEIIKQKRDDTDHTKQDITKENEIETFTI 6000
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6001 TSEKLKEKENSIKESTElsqtiAREISDSKIETIEEKKEIKIEQTTEiEDKSKVSKKEKRKQKRKEKSATRAtsQEKLKN 6080
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEE-----AKKADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKA--EEAKKA 1536
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6081 EKSEAISQEQKGEiniVSKTSDELKTEEisteiiltnenkEKKDTNEISKEIEKLILSEVIPDEIKLVPETMPIPIPKEE 6160
Cdd:PTZ00121 1537 DEAKKAEEKKKAD---ELKKAEELKKAE------------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6161 IKIIKEKIELSKSIEEQEIISDEIKLVPET--LSISISKEEIKPIKEIAEFPKPTEEKKVVSDKIKLEtivipisediSE 6238
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK----------AE 1671
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6239 NSIKEKTELPKPKQNEISDEIKLVPESlsisiskEEIQPIKEIIELSKSIEEKEEIINKTKDIVEEKGEIIKPMIDKDKK 6318
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEA-------EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6319 QEESSFKKSKRKNKQAKKIKHEEA-------------ETEIKSADE------DLLSSKIEKNIEILSTGSS--TPSPDTP 6377
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKkaeeirkekeaviEEELDEEDEkrrmevDKKIKDIFDNFANIIEGGKegNLVINDS 1824
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6378 KDIFQIEEKILNVTIPEQKIEVIDI-----LTIDEIKKDEKEIKNTTEQKIIFEEEKTLSKTQEEIEEINLQKIEEIPST 6452
Cdd:PTZ00121 1825 KEMEDSAIKEVADSKNMQLEEADAFekhkfNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPN 1904
|
890 900 910
....*....|....*....|....*....|...
gi 373194212 6453 SPIKKKVMKEDKSKNDDKEIHEIKSLTTEEKIV 6485
Cdd:PTZ00121 1905 NNMAGKNNDIIDDKLDKDEYIKRDAEETREEII 1937
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2812-3711 |
1.01e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 73.08 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2812 ESNWDITKKRETRKTHQEApktkipEKRARRGSEYSKEKLQKEKIKINMEQQKQVFETKDEIVVEDTSKINVKNNEVEIK 2891
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEET------ENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2892 KEKVEDVQPEKRVDVEKTKKIEAQKQDEKQEIQEEKHDVQQRSRSQEKkrkgkkkkpeksmddEIDKALKEIEDMDKQKK 2971
Cdd:pfam02463 238 RIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE---------------EELKLLAKEEEELKSEL 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2972 RDKSREQTKIKDTTQTVQTEKYKEDIEKKgvkpgeKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIE 3051
Cdd:pfam02463 303 LKLERRKVDDEEKLKESEKEKKKAEKELK------KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELL 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3052 KRNAKDEAKISKEKVESRKNESEKRSEIKIDSS----SEMRKIETKEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSV 3127
Cdd:pfam02463 377 AKKKLESERLSSAAKLKEEELELKSEEEKEAQLllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQ 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3128 KSTKTENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKSEKISETKVESKEKEPAKPKEQDKS 3207
Cdd:pfam02463 457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3208 KKNKKQKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEK--IKIEIDVKAPKDEKEKKITGKE 3285
Cdd:pfam02463 537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKsiAVLEIDPILNLAQLDKATLEAD 616
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3286 KEKKSESKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDskesstpkKEMKKAGEAEKQIKTKG 3365
Cdd:pfam02463 617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL--------TKELLEIQELQEKAESE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3366 GKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEKIIIEESKKEHLKLEsvvpNTEQSEMKKHKKSKSPKRGKKEE 3445
Cdd:pfam02463 689 LAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL----KQKIDEEEEEEEKSRLKKEEKEE 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3446 NLKFVEKEKTEKKETQGETIKLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQTDKIEIQSAIEKI 3525
Cdd:pfam02463 765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKE 844
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3526 PEKIIVEGSMETFTETVEIAKETEKVKVSDTKEEretplsEISKTEELEDQQPEQKSEMPSTLKNKKSNKSKEKHPIEKV 3605
Cdd:pfam02463 845 EQKLEKLAEEELERLEEEITKEELLQELLLKEEE------LEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3606 TPLSIVQEPKPNTsksqpstpksDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKSIEESIEIPDVASEKSIFKEKEI 3685
Cdd:pfam02463 919 IEERIKEEAEILL----------KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEE 988
|
890 900
....*....|....*....|....*.
gi 373194212 3686 STTLQPEIIPIIESEKDQIIEIDESK 3711
Cdd:pfam02463 989 RYNKDELEKERLEEEKKKLIRAIIEE 1014
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
277-1089 |
6.51e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 6.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 277 LERTKELLKRWENLSENVDERKRLIENE---MQEYNAYHAALQETEKWLLQISFQlmAHNSLYITNKEQTVSQIQQHENL 353
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQaekAERYKELKAELRELELALLVLRLE--ELREELEELQEELKEAEEELEEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 354 LVEIENYTSVLNDLKL-------KGNGQITRYVAVNSEIKTIiETQLQNVQESYNSLLNTALQIKKRLAESLIKFQEYEN 426
Cdd:TIGR02168 259 TAELQELEEKLEELRLevseleeEIEELQKELYALANEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 427 TLESIMKNLDAYEPEIA---QEMEAPMDTLDAAKQRFENARMLHNKLQGEKTRLALAVEACEAAVACVSRPGSPLDAPPV 503
Cdd:TIGR02168 338 ELAELEEKLEELKEELEsleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 504 QIPAREVEVRNKLEEL-IDQAQGHLMNVTKALNELEEQTRQKNVLRAWINQQRALcAEWKSRPAKLRSEAALAELQAMND 582
Cdd:TIGR02168 418 RLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAERELAQLQARLDSLER 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 583 LLGNVgERRTHALTELSLHEDDQDIEEGL--------NKLEAELTDAIAGkqAAQDLIqkyrtqVQNMQSWLDTlskkVD 654
Cdd:TIGR02168 497 LQENL-EGFSEGVKALLKNQSGLSGILGVlselisvdEGYEAAIEAALGG--RLQAVV------VENLNAAKKA----IA 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 655 VIEKGNG---------QTIGQKIASVKEITTEFESQGPGKLNEVKTLSDQVMDSVSNL--------DSQQIEEQIKSVER 717
Cdd:TIGR02168 564 FLKQNELgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvdDLDNALELAKKLRP 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 718 RYADI---GKKLQRKAQVL---DMTAQGIEATRQEIEENRdwiqqkKKQAQMSEPVGFDSKQAEERLLALKAMLKEAEGK 791
Cdd:TIGR02168 644 GYRIVtldGDLVRPGGVITggsAKTNSSILERRREIEELE------EKIEELEEKIAELEKALAELRKELEELEEELEQL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 792 QMVIDTLEKRVGNMQNELE--SNEQQQLENETKALRGEQSQLCTILT------EGISSATVAADARR-KFEADLERARSW 862
Cdd:TIGR02168 718 RKELEELSRQISALRKDLArlEAEVEQLEERIAQLSKELTELEAEIEeleerlEEAEEELAEAEAEIeELEAQIEQLKEE 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 863 IKSKSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSfSEKDLNDILKQgnnllKECSEEDRARLNKILDELNKDYEEL 942
Cdd:TIGR02168 798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAA-TERRLEDLEEQ-----IEELSEDIESLAAEIEELEELIEEL 871
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 943 KSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEvatssdvrtssiDILREQLAKYDRLKKEANEYADDIEKLMQQGK 1022
Cdd:TIGR02168 872 ESELEALLNERASLEEALALLRSELEELSEELRELE------------SKRSELRRELEELREKLAQLELRLEGLEVRID 939
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1023 SILPTVTDADKLELNEQLQNM-------KEAHGRVA---------GIINERALA-----------LQKNIDEAEESLARV 1075
Cdd:TIGR02168 940 NLQERLSEEYSLTLEEAEALEnkieddeEEARRRLKrlenkikelGPVNLAAIEeyeelkerydfLTAQKEDLTEAKETL 1019
|
890
....*....|....
gi 373194212 1076 AEAIQYMTDVQKEL 1089
Cdd:TIGR02168 1020 EEAIEEIDREARER 1033
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
3867-4625 |
8.02e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.56 E-value: 8.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3867 FGSVQDRRKDRSGTPLSAKSVENAK----DEREVDDLKEGQGVdAKISQDTLGENEGKAEkgemmVKKEVNVFEKIE-SE 3941
Cdd:PTZ00121 1097 FGKAEEAKKTETGKAEEARKAEEAKkkaeDARKAEEARKAEDA-RKAEEARKAEDAKRVE-----IARKAEDARKAEeAR 1170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3942 RFKDSRELVVENEDKSVKEKQETNKTVEellftVGKGEDVKNAVEELLEAERQAMVVEQKIVDIEKGETVPVKLEDSKfK 4021
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEVRKAEELRKAED-----ARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK-K 1244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4022 LEEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKVIEKGVEVPvDIKSVTKEIEGKITLPEEKVAE--FEK 4099
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAK-KAEEKKKADEAKKKAEEAKKADeaKKK 1323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4100 SIEVPIKINDTKLETEEIKLEDKVDSEKQERI--EIEDFKSIMKGIEDKTDLIEEKLIDTGKREDVSIKLKKIENKPTQD 4177
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAadEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4178 EEKIKEVpiniKDFESIIEKINSETILVEEKDLKEKIEIPLEIKSITEEVEDKTalfeekvvESEKSFKEVPVKIDYSKS 4257
Cdd:PTZ00121 1404 KKKADEL----KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA--------EEAKKAEEAKKKAEEAKK 1471
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4258 QEEIKVEEKIVEKQEtivnkDFKSKMENIEDKTILEENIIESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYY 4337
Cdd:PTZ00121 1472 ADEAKKKAEEAKKAD-----EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4338 FTDLVKpywfnyrpyiKAEidfyrhfkIVKILEENVPAPVLPRSDSIERIVQESIMKNSKEEEKKIESAEQSETEYTNAS 4417
Cdd:PTZ00121 1547 KADELK----------KAE--------ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4418 QEIIKeKSKETENKTKDTKESETEYKHVLQESIEEKSKKIEKKTEDIEESEAEYRKYALIgetfkypistfYKLESEWVK 4497
Cdd:PTZ00121 1609 AEEAK-KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA-----------KKAEEDKKK 1676
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4498 SKLIQEKEVTLIPVEESESTNPEINKEIIQIY----EEEKLPIELKELEEVIPTSVEESKLTDVEVKSpiKSEELEV--- 4570
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKkkeaEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK--KAEEAKKdee 1754
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 4571 -KNEKVTLSSGEESKPIEVEIKKE--IIEIYEGEKPTLKLEEDKKIINIEKDTMKVIE 4625
Cdd:PTZ00121 1755 eKKKIAHLKKEEEKKAEEIRKEKEavIEEELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
5551-6347 |
2.33e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 68.84 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5551 QTIEFEALEADKIMEVNGTQEKIAEKSKIETKEQSSVKKNKKSKKGKSDKDQSKHEFKDKEQDKQIDNAQTTEVELKLKD 5630
Cdd:pfam02463 265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5631 EITKESEIKDQEEAKENISEIKSKEIQEKSNENIFDNESELLQETKSDKSMQSEKRKKKSKERKVEIAPKQVIETFIEEN 5710
Cdd:pfam02463 345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5711 KVLESEIQKEILKEQSEAKDIQDIKATTELVQETIYEKptssgkrKGKSKEKKKAITTEIAIKEKEVSRPEIKEILKKES 5790
Cdd:pfam02463 425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLK-------DELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5791 DIEEIKEIEEIEEKLKTIMKSEDEYKSEIVQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISLEQI 5870
Cdd:pfam02463 498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5871 IEISIEKNKPEIKGKISEKELEIEEDKEIQKEvqtsikceiENKPEVVQETKFEKSPKKRKGKSKETKieTISEQITKIS 5950
Cdd:pfam02463 578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD---------KATLEADEDDKRAKVVEGILKDTELTK--LKESAKAKES 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5951 IDEKKLSEFEAKEEISSQIKEEEIIKQKRDDTDHTKQDITKENEIETFTITSEKLKEKENSIKESTELSQTIAREISDSK 6030
Cdd:pfam02463 647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6031 IETIEEKKeikieqttEIEDKSKVSKKEKRKQKRKEKSATRATSQEKLKNEKSEAISQEQKGEINIVSKTSDELKTEEIS 6110
Cdd:pfam02463 727 VQEAQDKI--------NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6111 TEIILTNENKEKKDTNEISKEIEKLILSEVIPDEiklvpETMPIPIPKEEIKIIKEKIELSKSIEEQEIISDEIKLVPET 6190
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKE-----EELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELL 873
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6191 LSISISKEEIKPIKEIAEfpkptEEKKVVSDKIKLETIVIPISEDISENSIKEKTELPKPKQNEISDEIKlvpeslsisi 6270
Cdd:pfam02463 874 LKEEELEEQKLKDELESK-----EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPE---------- 938
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 6271 sKEEIQPIKEIIELSKSIEEKEEIINKTKDIVEEKGEIIKPMI-DKDKKQEESSFKKSKRKNKQAKKIKHEEAETEIK 6347
Cdd:pfam02463 939 -ELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIeEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10930-11117 |
3.85e-10 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 64.00 E-value: 3.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10930 WAQLENDLWRLEKWLEFAEgTQSAQHSPPGNIEQLEDVIQDHREFVLDLDCHESILASLNTVGAHLADHTEEllRATQLR 11009
Cdd:cd00176 2 LQQFLRDADELEAWLSEKE-ELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP--DAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 11010 DRLAVANTRWVKVCKVAAHWQEQLQTALMSnEQFHRIIEELVTWLEKTEVSIRASEPVDlteSPEIMTAKYNKFRELRSD 11089
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDL-QQFFRDADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKELEEE 154
|
170 180
....*....|....*....|....*...
gi 373194212 11090 LERCEPRVLSLQESANQLLDEKGETRAR 11117
Cdd:cd00176 155 LEAHEPRLKSLNELAEELLEEGHPDADE 182
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10347-10546 |
8.50e-10 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 62.85 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10347 LLAWIGETEIRIQDCDSPNEPEET---LKKLEcEIQSDIALKQRELLWIQNTGQDLVEVAEEEESeRLQRSLDELNERWD 10423
Cdd:cd00176 12 LEAWLSEKEELLSSTDYGDDLESVealLKKHE-ALEAELAAHEERVEALNELGEQLIEEGHPDAE-EIQERLEELNQRWE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10424 RLVAMGKARASKLMDLMRTMSTLEKrINELRSWLASVESQLSETFVVEAIEQscIDKKLDDHEHLQKTIEAESGNIGEVL 10503
Cdd:cd00176 90 ELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLES--VEELLKKHKELEEELEAHEPRLKSLN 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 373194212 10504 NLCEILLNDCDAwktSFNNAIKSGMEGLERRWTTTCVKSAERK 10546
Cdd:cd00176 167 ELAEELLEEGHP---DADEEIEEKLEELNERWEELLELAEERQ 206
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
212-418 |
1.29e-08 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 59.38 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDLpDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:cd00176 12 LEAWLSEKEELLSST-DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEiqERLEELNQRWEE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 290 LSENVDERKRLIENEMQEYNAYHAALQEtEKWLLQISFQLMAHNslYITNKEQTVSQIQQHENLLVEIENYTSVLNDLKL 369
Cdd:cd00176 91 LRELAEERRQRLEEALDLQQFFRDADDL-EQWLEEKEAALASED--LGKDLESVEELLKKHKELEEELEAHEPRLKSLNE 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 373194212 370 KGNGQITRyvaVNSEIKTIIETQLQNVQESYNSLLNTALQIKKRLAESL 418
Cdd:cd00176 168 LAEELLEE---GHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
991-1854 |
1.81e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.38 E-value: 1.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 991 DILREQLAKYDRLKKEAnEYADDIEKLMQQGKSILPTVTDADKLELNEQLQNMKEAHGRVAGIINEralaLQKNIDEAEE 1070
Cdd:TIGR02168 193 DILNELERQLKSLERQA-EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE----LTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1071 SL----ARVAEAIQYMTDVQKELHELNkpigSRVEDVEAMLDAYERILNDLKANKAKLSdlqsinvADLHGVLTQQDDLM 1146
Cdd:TIGR02168 268 KLeelrLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLEELE-------AQLEELESKLDELA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1147 KAIESQIAKLRQLLLLRQQFIALITEittFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIA 1226
Cdd:TIGR02168 337 EELAELEEKLEELKEELESLEAELEE---LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1227 AEGSTVDRNNITEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANELAEILDWLEDKEKEVKSRpllerdpisvEAE 1306
Cdd:TIGR02168 414 DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA----------ERE 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1307 LQKHNELCDAV----NEHLDRIRNLKNSVPHEEGMPGsLKEMLSEAVSLLTSLPREME----ERGNYL--ESNMKLRQEY 1376
Cdd:TIGR02168 484 LAQLQARLDSLerlqENLEGFSEGVKALLKNQSGLSG-ILGVLSELISVDEGYEAAIEaalgGRLQAVvvENLNAAKKAI 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1377 AALTEKLR--------SWVREAEI---RLESDKDGLDFENILSDLEEHKIYFSsePSI-----RELVSQQIQQA------ 1434
Cdd:TIGR02168 563 AFLKQNELgrvtflplDSIKGTEIqgnDREILKNIEGFLGVAKDLVKFDPKLR--KALsyllgGVLVVDDLDNAlelakk 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1435 -----------GDKIWPS--------------LNTS----EQEELSAEQQQHTQLLKNTLNTAKSQRARLEQGAETWRDY 1485
Cdd:TIGR02168 641 lrpgyrivtldGDLVRPGgvitggsaktnssiLERRreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1486 TQTLERvraviarsrftdEPVTTLAGLQFNIQKITHALNDIQNQQFEL-DLLIERSQEVLRLADAnnkktiEAQISEISA 1564
Cdd:TIGR02168 721 LEELSR------------QISALRKDLARLEAEVEQLEERIAQLSKELtELEAEIEELEERLEEA------EEELAEAEA 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1565 EWKELVSGLEGRRDALEALSKHWEDLEAQWSlietkvtaiEEKGKLLDTVVRSKQHLYDTIKSLHELVTEAEKLKPMAAE 1644
Cdd:TIGR02168 783 EIEELEAQIEQLKEELKALREALDELRAELT---------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1645 VKALSGPVLAYlaaftEAPAHALEEKLNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLy 1724
Cdd:TIGR02168 854 IESLAAEIEEL-----EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL- 927
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1725 ifgpdqdatEEELDELRWAVEQLLEsgkKFSGSTKARYQASQQLVPSDLAQHLTALELCAEATAQ----------AMEEK 1794
Cdd:TIGR02168 928 ---------ELRLEGLEVRIDNLQE---RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKikelgpvnlaAIEEY 995
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1795 QREQKRARTVRSDYlTDLDEVQAWIRQAELKVQDRSIEpvPLKDQLRQVQEELGTITDKL 1854
Cdd:TIGR02168 996 EELKERYDFLTAQK-EDLTEAKETLEEAIEEIDREARE--RFKDTFDQVNENFQRVFPKL 1052
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
2960-3280 |
4.09e-08 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 61.18 E-value: 4.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2960 LKEIEDMDKQKKRDKSREQTkikdttqTVQTEKYKEDIEKKGVKPGEKKK-----QNKSKMEKIRDESEIAMNQANAKEQ 3034
Cdd:NF033838 104 LNVLKEKSEAELTSKTKKEL-------DAAFEQFKKDTLEPGKKVAEATKkveeaEKKAKDQKEEDRRNYPTNTYKTLEL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3035 MKSKNDTKESKEEKNIEKRNAK---DEAKI--SKEKVESRKNESEKRSEIKIDsssemrKIETKEEKAQKDSANLSKKKQ 3109
Cdd:NF033838 177 EIAESDVEVKKAELELVKEEAKeprDEEKIkqAKAKVESKKAEATRLEKIKTD------REKAEEEAKRRADAKLKEAVE 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3110 KGkeqtgtvKDKSNKDSVKStkteneseQMKKAIFIEDKTEIQKEKDIKPVENignldqlQKQEDTKSVKLMKSEKI--- 3186
Cdd:NF033838 251 KN-------VATSEQDKPKR--------RAKRGVLGEPATPDKKENDAKSSDS-------SVGEETLPSPSLKPEKKvae 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3187 SETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQ---KEEKKTEQSKQKKSVEKSEVIDIKLEENEK 3263
Cdd:NF033838 309 AEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELelvKEEAKEPRNEEKIKQAKAKVESKKAEATRL 388
|
330
....*....|....*..
gi 373194212 3264 IKIEIDVKAPKDEKEKK 3280
Cdd:NF033838 389 EKIKTDRKKAEEEAKRK 405
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
606-1130 |
5.31e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 60.82 E-value: 5.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 606 DIEEGLNKLEAELTDAIAGKQAAQDLIQKY---RTQVQNMQSWLDTLSKKVDVIEKgNGQTIGQKIASVKEITTEFESQG 682
Cdd:PRK02224 217 ELDEEIERYEEQREQARETRDEADEVLEEHeerREELETLEAEIEDLRETIAETER-EREELAEEVRDLRERLEELEEER 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 683 PGKLNEV-------KTLSDQVMD------------SVSNLDSQQIEEQIKSVERRYADI---GKKLQRKAQVLDmtaQGI 740
Cdd:PRK02224 296 DDLLAEAglddadaEAVEARREEledrdeelrdrlEECRVAAQAHNEEAESLREDADDLeerAEELREEAAELE---SEL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 741 EATRQEIEENRDWIQQKKKQAQ-MSEPVGF---DSKQAEERLLALKAMLKEAEGKqmvIDTLEKRVGNMQNELEsnEQQQ 816
Cdd:PRK02224 373 EEAREAVEDRREEIEELEEEIEeLRERFGDapvDLGNAEDFLEELREERDELRER---EAELEATLRTARERVE--EAEA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 817 LENETKALRGEQSqlctilTEGISSATVAADARRKFEaDLERARSWIKSKSNNLKKlsgylplkasKVEQdIVQHGELET 896
Cdd:PRK02224 448 LLEAGKCPECGQP------VEGSPHVETIEEDRERVE-ELEAELEDLEEEVEEVEE----------RLER-AEDLVEAED 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 897 DIDSFSEK--DLNDILKQGnnllKECSEEDRARLnkilDELNKDYEELKSEAQEKQAALADLlqgrkafESEIDKCqrwi 974
Cdd:PRK02224 510 RIERLEERreDLEELIAER----RETIEEKRERA----EELRERAAELEAEAEEKREAAAEA-------EEEAEEA---- 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 975 neAEVATSSDVRTSSIDILREQLAKYDRLKKEANEYADDIEKLMQQGKSiLPTVTDadklELNEQLQNMKEAHGRVAGII 1054
Cdd:PRK02224 571 --REEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREA-LAELND----ERRERLAEKRERKRELEAEF 643
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 1055 NERAL-ALQKNIDEAEESLARVAEAIQYMTDvqkELHELNKPIGSrvedVEAMLDAYERILNDLKANKAKLSDLQSI 1130
Cdd:PRK02224 644 DEARIeEAREDKERAEEYLEQVEEKLDELRE---ERDDLQAEIGA----VENELEELEELRERREALENRVEALEAL 713
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10226-10440 |
9.41e-08 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 57.07 E-value: 9.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10226 RYKEYEEKAKEINSSFTEIGQAFSTAfhSSPASLTRTKQQLESVHQMQNRLSSMSVDLESLGVMIQQLREDLSPtDIKSL 10305
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP-DAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10306 NEQRALFRLQHEDLEHQAALLICRLEERCGLYDRWRDrLARLLAWIGETEIRIQDCDSPNEPEET---LKKLEcEIQSDI 10382
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLESVeelLKKHK-ELEEEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 10383 ALKQRELLWIQNTGQDLVEVAEEEESERLQRSLDELNERWDRLVAMGKARASKLMDLM 10440
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
773-1309 |
1.03e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 773 QAEERLLALKAMLKEAEGKQMVIDTLEKRVGNMQNELES--NEQQQLENETKALRGEQSQLCTILTEGISSATVAADARR 850
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEEleAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 851 KFEADLERARSWIKSKSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSfSEKDLNDILKQGNNLLKECSEEDRARLNK 930
Cdd:COG1196 299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE-AEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 931 I--LDELNKDYEELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEVATSS------DVRTSSIDILREQLAKYDR 1002
Cdd:COG1196 378 EeeLEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleeeeeEEEEALEEAAEEEAELEEE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1003 LKKEANEYADDIEKLMQQGKSILPTVTDADKLELNE--QLQNMKEAHGRVAGIINERALALQKNIDEAEESLARVAEAiq 1080
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLllLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA-- 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1081 YMTDVQKELHELNKPIGSRVEDVEAMLDAYeriLNDLKANKAKLSDLQSINVADLHGVLTQQDDLMKAIESQIAKLRQLL 1160
Cdd:COG1196 536 YEAALEAALAAALQNIVVEDDEVAAAAIEY---LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1161 LLRQQFIALITEIT----TFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIAAEGSTVDRNN 1236
Cdd:COG1196 613 ARYYVLGDTLLGRTlvaaRLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 1237 I--TEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANELAEILDWLEDKEKEVKSRPLLERDPISVEAELQK 1309
Cdd:COG1196 693 LelEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1268-1477 |
1.76e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 56.30 E-value: 1.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1268 EHKRLANELAEILDWLEDKEKEVKSrPLLERDPISVEAELQKHNELCDAVNEHLDRIRNLKNS----VPHEEGMPGSLKE 1343
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSS-TDYGDDLESVEALLKKHEALEAELAAHEERVEALNELgeqlIEEGHPDAEEIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1344 MLSEAVSLLTSLPREMEERGNYLESNMKLRQEYAALTEkLRSWVREAEIRLESDKDGLDFENILSDLEEHKIyFSSEPSI 1423
Cdd:cd00176 80 RLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALASEDLGKDLESVEELLKKHKE-LEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 373194212 1424 RELVSQQIQQAGDKIWPSLNTSEQEELSAEQQQHTQLLKNTLNTAKSQRARLEQ 1477
Cdd:cd00176 158 HEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1807-2009 |
8.70e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 53.99 E-value: 8.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1807 DYLTDLDEVQAWIRQAELKVQDRSIEPVP-----LKDQLRQVQEELGTITDKLERLTRNGRTIAENTRDDTEKqlIDSTV 1881
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLesveaLLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE--IQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1882 HNVTEQLNQVRNWLDERKQVVADTIDAWQRFLSLYEaVRTWTEEKRQFL--VEPLKLSTLVQARQRLHE-YSTAVKSCKQ 1958
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALasEDLGKDLESVEELLKKHKeLEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 373194212 1959 INKNLSDMGKELESIGQVCSVGDLPEKLLEAEEAKVQVEGQLLERNALLQE 2009
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1423-1907 |
2.03e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1423 IRELVSQQIQQAGDKIW------PSLNTSEQEELSAE----QQQHTQL--LKNTLNTAKSQRARLEQGAETWRDYTQTLE 1490
Cdd:COG4717 43 IRAMLLERLEKEADELFkpqgrkPELNLKELKELEEElkeaEEKEEEYaeLQEELEELEEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1491 RVRAVIARSRFTDEPVTTLAGLQFNIQKITHALNDIQNQQFELDLL---IERSQEVLRLADANNKKTIEAQISEISAEWK 1567
Cdd:COG4717 123 KLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELeaeLAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1568 ELVSGLEGRRDALEALSKHWEDLEAQWSLIETKVTAIEEKGKLLDTVVRSKqhLYDTIKSLHELVTEAEKLKPMAAEVKA 1647
Cdd:COG4717 203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLL--IAAALLALLGLGGSLLSLILTIAGVLF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1648 LSGPVLAYLAAFTEAPAHALEEKLNKLQNSV-------ESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERA 1720
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAEELQALPaleeleeEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1721 SNLyifgpDQDATEEELDEL--------RWAVEQLLESGKKFSGSTKARYQASQQLVPSDLAQHLTALELCAEATAQAME 1792
Cdd:COG4717 361 EEL-----QLEELEQEIAALlaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1793 EKQREQKRARTVRSDYLTDLDEVQAWIRQAElkvQDRSIEpvplkDQLRQVQEELGTITDKLERLTRN--GRTIAENTRD 1870
Cdd:COG4717 436 ELEEELEELEEELEELREELAELEAELEQLE---EDGELA-----ELLQELEELKAELRELAEEWAALklALELLEEARE 507
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 373194212 1871 DTEKQLIDSTVHNVTEQLNQV------RNWLDERKQVVADTID 1907
Cdd:COG4717 508 EYREERLPPVLERASEYFSRLtdgryrLIRIDEDLSLKVDTED 550
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
705-1077 |
2.57e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.46 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 705 SQQIEEQIKSVERRYADIGKKLQRKAQVLDMTAQGIEATRQEIEENRDWIQQKKKQAQMS----EPVGFDSKQAEERLLA 780
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLkerlEELEEDLSSLEQEIEN 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 781 LKAMLKEAEGKqmvIDTLEKRVGNMQNELESNEQQQLENETKALRGEQSQLCTILTEgISSATVAADARrkfeadlerar 860
Cdd:TIGR02169 756 VKSELKELEAR---IEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSR-IEARLREIEQK----------- 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 861 swiksksnnLKKLSGYLPLKASKVEQDIVQHGELETDIDSFSEKdlndilkqgnnllkecseedrarlnkiLDELNKDYE 940
Cdd:TIGR02169 821 ---------LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE---------------------------IENLNGKKE 864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 941 ELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEVATssDVRTSSIDILREQLAKYDRLKKEANEYADDIEKLMQQ 1020
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI--EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 1021 GKSILPTVTDADKLELNEQlqnMKEAHGRVAGIINERAlalqknIDEAEESLARVAE 1077
Cdd:TIGR02169 943 DEEIPEEELSLEDVQAELQ---RVEEEIRALEPVNMLA------IQEYEEVLKRLDE 990
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
10088-10336 |
8.46e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 8.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10088 EQFNILTNQHNEtLAKIMERHAAVRDRLAAWDRYKLDQSKLlywlKEIERERSQLRFRFIQiQRLDEILQRIESLLEKIP 10167
Cdd:COG4913 232 EHFDDLERAHEA-LEDAREQIELLEPIRELAERYAAARERL----AELEYLRAALRLWFAQ-RRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10168 EGEAQLESLQRQQETLLVKCDEAlavtiHRDHAAS-VQRINNLSSSLEMWRDHIPRIQKRYKEYEEKAKEINSSFTEIGQ 10246
Cdd:COG4913 306 RLEAELERLEARLDALREELDEL-----EAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10247 AFSTAFHSSPASLTRTKQQLESVHQmqnrlssmsvDLESLGVMIQQLREDLsptdiKSLNEQRALFRLQHEDLEHQAALL 10326
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALEE----------ALAEAEAALRDLRREL-----RELEAEIASLERRKSNIPARLLAL 445
|
250
....*....|
gi 373194212 10327 ICRLEERCGL 10336
Cdd:COG4913 446 RDALAEALGL 455
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
96-305 |
1.27e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 50.52 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 96 EFLKAKKEMEDWLRIARGSVQDCMGVGDAEWAKDKLETIKIVATRITEGQHLLSTLQtAFTKAIDTAVPEQQDQLRSDMA 175
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALN-ELGEQLIEEGHPDAEEIQERLE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 176 GLLSSWEQLSIDLNTVQAQLKSLLHRWDDHSEAHgKLKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKT 255
Cdd:cd00176 83 ELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALAS-EDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 256 ELDHLMDEASELSKLAKKNTPL---ERTKELLKRWENLSENVDERKRLIENEM 305
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEeieEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1306-2145 |
1.72e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.92 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1306 ELQKHNELCDAVNE--HLDRIrnlKNSVPHEEGMPGSLKEMLSEAVslltslpremEERGNYLESNMKLRQEYAALTEKL 1383
Cdd:pfam12128 164 SLARQFALCDSESPlrHIDKI---AKAMHSKEGKFRDVKSMIVAIL----------EDDGVVPPKSRLNRQQVEHWIRDI 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1384 RSWVREAEIRLESDKDGLDFENILSDLEE----HKIYFSSEPSIRELvsQQIQQAGDKiwpSLNtSEQEELSAEQQQHTQ 1459
Cdd:pfam12128 231 QAIAGIMKIRPEFTKLQQEFNTLESAELRlshlHFGYKSDETLIASR--QEERQETSA---ELN-QLLRTLDDQWKEKRD 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1460 LLKNTLNTAKsqrarleqgaETWRDYTQTLERVRAviARSRFTDEPVTTLAGLQFNIQKIThalNDIQNQQFELDLLIER 1539
Cdd:pfam12128 305 ELNGELSAAD----------AAVAKDRSELEALED--QHGAFLDADIETAAADQEQLPSWQ---SELENLEERLKALTGK 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1540 SQEVLRLADANNKKTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWslietkvtaieekgklldtvvrsKQ 1619
Cdd:pfam12128 370 HQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL-----------------------RE 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1620 HLYDTIKSLHElvtEAEKLKPMAAEVKALsgpvlayLAAFTEAPahalEEKLNKLQNsvESLIDTLQTKSKKADEDLETF 1699
Cdd:pfam12128 427 QLEAGKLEFNE---EEYRLKSRLGELKLR-------LNQATATP----ELLLQLENF--DERIERAREEQEAANAEVERL 490
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1700 ESTEREIDQLRKRLNEARERASnlyifgpdqdateEELDELRWAVEQLLESGKKFSGS--------------TKARYQAS 1765
Cdd:pfam12128 491 QSELRQARKRRDQASEALRQAS-------------RRLEERQSALDELELQLFPQAGTllhflrkeapdweqSIGKVISP 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1766 QQLVPSDLAQHLTALELCAEATAQAMEEKQReqkraRTVRSDYLTDLDEVQAWIRQAELKVQDRSiepvplkDQLRQVQE 1845
Cdd:pfam12128 558 ELLHRTDLDPEVWDGSVGGELNLYGVKLDLK-----RIDVPEWAASEEELRERLDKAEEALQSAR-------EKQAAAEE 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1846 ELGTITDKLERLTRN---GRTIAENTRDD---------TEKQLIDSTVHNVTEQLNQVRNWLDERKQVVADTIDAW-QRF 1912
Cdd:pfam12128 626 QLVQANGELEKASREetfARTALKNARLDlrrlfdekqSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWlEEQ 705
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1913 LSLYEAVRTWTEEKRQFLVEPL--KLSTLVQArqRLHEYSTAVKSCKQINKnlsDMGKELESIGqvcsvgdlpeklleae 1990
Cdd:pfam12128 706 KEQKREARTEKQAYWQVVEGALdaQLALLKAA--IAARRSGAKAELKALET---WYKRDLASLG---------------- 764
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1991 eakvqVEGQ-LLERNALLQETSEEWEQCERKMKEVKTWiEKAKQSLESPQNKKkpLRDQHSIREKMLSDIAIQKTKIGIS 2069
Cdd:pfam12128 765 -----VDPDvIAKLKREIRTLERKIERIAVRRQEVLRY-FDWYQETWLQRRPR--LATQLSNIERAISELQQQLARLIAD 836
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2070 MEKLQVHFRSGIGGDSRIGETVDELLAELD---------NLHANVKEQTTALEGCLAQIDQYQQEIQQLRQQIMQVEQQL 2140
Cdd:pfam12128 837 TKLRRAKLEMERKASEKQQVRLSENLRGLRcemsklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHF 916
|
....*
gi 373194212 2141 RTVLS 2145
Cdd:pfam12128 917 KNVIA 921
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3873-4659 |
2.51e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.28 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3873 RRKDRSGTPLSAKSVENAKDEREVDDLKE-GQGVDAKISQDTLGENEGKAEKGEMMVKKEVNVFEKIESERFKDSRELVV 3951
Cdd:pfam02463 237 ERIDLLQELLRDEQEEIESSKQEIEKEEEkLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3952 ENEDKSVKEKQETNKTVE--------ELLFTVGKGEDVKNAVEELLEAERQAMVVEQKIVDIEKGETVPVKLEDS-KFKL 4022
Cdd:pfam02463 317 KESEKEKKKAEKELKKEKeeieelekELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKlKEEE 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4023 EEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKV--IEKGVEVPVDIKSVTKEIEGKITLPEEKVAEFEKS 4100
Cdd:pfam02463 397 LELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIelKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4101 IEVPIKINDTKLETEEIKLEDKVDSEKQERIEIEDFKSIMKGIEDKTDLIEEKLIDTGKREDVSIKLKKIENKPTQDEEK 4180
Cdd:pfam02463 477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSAT 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4181 IKEVPINIKDFESIIEKINSETILVEEKDLKEKIEIPLEIKSIteEVEDKTALFEEKVVESEKSFKEVPVKIDYSKSQEE 4260
Cdd:pfam02463 557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI--DPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4261 IKVEEKIVEKQETivnkDFKSKMENIEDKTILEENIIESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYYFTD 4340
Cdd:pfam02463 635 TKLKESAKAKESG----LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4341 LVKpywfnyrpyIKAEIDFYRHFKIVKILEENVPAPVLPRSDSIERIVQESIMKNSKEEEKKIESAEQSETEYTNASQEI 4420
Cdd:pfam02463 711 ELK---------KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4421 IKEKSKETENKTKDTKESETE-----YKHVLQESIEEKSKKIEKKTEDIEESEAEYRKYALIGETFKYPISTFYKLESEW 4495
Cdd:pfam02463 782 KTEKLKVEEEKEEKLKAQEEElraleEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4496 VKSKLIQEKEVTLIPVEESESTNPEINKEIIQIYEEEKLPIELKELEEvipTSVEESKLTDVEVKSPIKSEELEVKNEKV 4575
Cdd:pfam02463 862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL---NLLEEKENEIEERIKEEAEILLKYEEEPE 938
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4576 TLSSGEESKPIEVEIKKEIIEIYEGEKPTLKLEEDKKIINIEKDTMKVIEEVTTEIKSTDRILDQTAALIEDLTKELDMI 4655
Cdd:pfam02463 939 ELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
|
....
gi 373194212 4656 KKEE 4659
Cdd:pfam02463 1019 LKEF 1022
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
840-1105 |
5.17e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 840 SSATVAADARRKFEADLERARSWIKSKSNNLKKLSGylplKASKVEQDIvqhgeletdidsfseKDLNDILKQGNNLLKE 919
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQL---------------AALERRIAALARRIRA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 920 cSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLLqgRKAFESEIdkcqrwINEAEVATSSDVRTSSIDILR--EQL 997
Cdd:COG4942 74 -LEQELAALEAELAELEKEIAELRAELEAQKEELAELL--RALYRLGR------QPPLALLLSPEDFLDAVRRLQylKYL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 998 AKYDRlkKEANEYADDIEKLMQQGKSIlptvtDADKLELNEQLQNMKEAHGRVAGIINERALALQKNIDEAEESLARVAE 1077
Cdd:COG4942 145 APARR--EQAEELRADLAELAALRAEL-----EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
|
250 260
....*....|....*....|....*...
gi 373194212 1078 AIQYMTDVQKELHELNKPIGSRVEDVEA 1105
Cdd:COG4942 218 LQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
8257-8448 |
7.01e-05 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 50.81 E-value: 7.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8257 QTVEEEAPKIEEISTQTMESPVKKMEEyavqtspiedikEIVPIETEEIQVQTVATEVASIEAQTSPTAPfmeIETQTAE 8336
Cdd:PRK10811 854 QVEEQREAEEVQVQPVVAEVPVAAAVE------------PVVSAPVVEAVAEVVEEPVVVAEPQPEEVVV---VETTHPE 918
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8337 KVVVAVEQQttPPPIEEKILTgiAVQTVTPEVPKTTETEAQTSKPTTPEITTLDFNVQADLIEQPVVDVVETQTTPEESP 8416
Cdd:PRK10811 919 VIAAPVTEQ--PQVITESDVA--VAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETV 994
|
170 180 190
....*....|....*....|....*....|..
gi 373194212 8417 RQAETHETESQtiQPEPTQEIMIQTCPVTFAP 8448
Cdd:PRK10811 995 TAVEPEVAPAQ--VPEATVEHNHATAPMTRAP 1024
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
10085-10837 |
8.03e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 8.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10085 SKTEQFNILTNQHNETLAKIMERHAAVRDRLAAWDRYKLDQSKLLywlKEIERERSQLRFRFIQIQRLDEILQRIESLLE 10164
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE---QQKQILRERLANLERQLEELEAQLEELESKLD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10165 kipEGEAQLESLQRQQETLLVKCDEALAvtihrDHAASVQRINNLSSSLEMWRDHIPRIQKRYKEYEEKAKEINssftei 10244
Cdd:TIGR02168 334 ---ELAEELAELEEKLEELKEELESLEA-----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN------ 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10245 gqafstafhsspASLTRTKQQLESVHQMQNRLSSmsvDLESLGVMIQQLREDLSPTDIKSLNEQRALFRLQHEDLEHQAA 10324
Cdd:TIGR02168 400 ------------NEIERLEARLERLEDRRERLQQ---EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10325 LLICRLEERCGLYDRWRDRLARLLAWIGETEIRIQDCDSPNEPEETLKKleceIQSDIALKQRELLWIQNTGQDLVEVAE 10404
Cdd:TIGR02168 465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK----NQSGLSGILGVLSELISVDEGYEAAIE 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10405 EEESERLQRSLDELNERWDRLVA-MGKARASKLMDLMRTMSTLEKRINELRSWLASVESqlsetFVVEAIEQSCIDKKLd 10483
Cdd:TIGR02168 541 AALGGRLQAVVVENLNAAKKAIAfLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG-----FLGVAKDLVKFDPKL- 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10484 dhehlQKTIEAESGNIGEVLNLcEILLNDCDAWKTSFNNAIKSGmEGLERRWTTTcvKSAERKGNIILAWKI-LQELEKI 10562
Cdd:TIGR02168 615 -----RKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDG-DLVRPGGVIT--GGSAKTNSSILERRReIEELEEK 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10563 RLEQEGWLAETDKALAELENNLDEVSKDESKK---AIEKARSISEDVEAHEPVIKIIEQNFGRLARTGLEPDNLKSLISE 10639
Cdd:TIGR02168 686 IEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10640 TRRLIDKWQTFKPRANAVLLALQKGQKNYRdfitvhgaavvgltqvdvrltrtqhlatpEQKASIRRRLQQLNEieeELR 10719
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQLK-----------------------------EELKALREALDELRA---ELT 813
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10720 TQNITLQKadelaLKVMQECHPDDVANIQELVDEYQLLWKDIKKRVASLRAEIEGQEKSEVDEAVQVETLKFEQDSAVQV 10799
Cdd:TIGR02168 814 LLNEEAAN-----LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 373194212 10800 DTLPRLLRMTSS------DAYLMELEAALVECNDALDTLQLAIA 10837
Cdd:TIGR02168 889 LALLRSELEELSeelrelESKRSELRRELEELREKLAQLELRLE 932
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4740-5282 |
9.14e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 9.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4740 KKEESKETPLLIKELEEKDTTETAELSQIMEQLTAEIKKKEIEEISLLPKESEVIEKKDIDIIETSELTRTMEELITAIK 4819
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAA 1415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4820 EIS-TDEIIDQTEEKKMEKNITEEllTTSQSKTEEEVKPAMESSKIERVGK---ETKSEKNKKKQKKQNEKKEETPVLEN 4895
Cdd:PTZ00121 1416 AKKkADEAKKKAEEKKKADEAKKK--AEEAKKADEAKKKAEEAKKAEEAKKkaeEAKKADEAKKKAEEAKKADEAKKKAE 1493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4896 PIMTEQENIKKIVEKSVSEKKKTSKESKKKEVKEASKEEKIITEEPVKSYPLEK--DINIVTEITETEKLVNGKAIEIID 4973
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEEKKKAEEAKKAE 1573
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4974 LDAIQSSTNQQSSKEGKTKPVEKSKKEETKTKSGKQKQFKEKPDIKPKStsdKELKKQDKQENSSPDSKKKREGKSKKTN 5053
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5054 DIPtpvSQEIVNEISSEEFKKEEnqiEIKQASQEEIQPSVCTKSWASIVSMKGNTETNNSTDISKViPEESISETLKLEK 5133
Cdd:PTZ00121 1651 ELK---KAEEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK-EAEEKKKAEELKK 1723
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5134 IEKVEEIVPEELQNSPAHQKRMKHQKKKDAKQEKNVTEIKVSSTNTENE--GEKEITIEE-----------SQELITKDS 5200
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEirKEKEAVIEEeldeedekrrmEVDKKIKDI 1803
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5201 NKSYAQVAASNKRTSPQFNQ---------EDIIIAKPTPI---------MLNENTEKKEIAQEEALIITEIENvKEETIK 5262
Cdd:PTZ00121 1804 FDNFANIIEGGKEGNLVINDskemedsaiKEVADSKNMQLeeadafekhKFNKNNENGEDGNKEADFNKEKDL-KEDDEE 1882
|
570 580
....*....|....*....|
gi 373194212 5263 SEKEVTMDKKFDELVIEKDI 5282
Cdd:PTZ00121 1883 EIEEADEIEKIDKDDIEREI 1902
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
2951-3382 |
2.69e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 48.47 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2951 SMDDEIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDIEKKGVKpGEKKKQNKSKMEKIrdeSEIAMNQAN 3030
Cdd:NF033838 50 SSGNESQKEHAKEVESHLEKILSEIQKSLDKRKHTQNVALNKKLSDIKTEYLY-ELNVLKEKSEAELT---SKTKKELDA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3031 AKEQMKsKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKN---ESEKRSEIKIDSSsemrkietkEEKAQKDSANLSKK 3107
Cdd:NF033838 126 AFEQFK-KDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRRNyptNTYKTLELEIAES---------DVEVKKAELELVKE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3108 KqkgkeqtgtVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQK-EKDIKPVENIGNLDQLQKQEDTKSvklmKSEKI 3186
Cdd:NF033838 196 E---------AKEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKaEEEAKRRADAKLKEAVEKNVATSE----QDKPK 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3187 SETKVESKeKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEKIKI 3266
Cdd:NF033838 263 RRAKRGVL-GEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLEL 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3267 EI---DVKAPKDEKEkkitgkekekksESKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKE 3343
Cdd:NF033838 342 EIaesDVKVKEAELE------------LVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRKAAEE 409
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 373194212 3344 SSTPKK--EMKKAGEAEKQIKTKGGKKSKKEADINQKPATE 3382
Cdd:NF033838 410 DKVKEKpaEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQ 450
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1515-2036 |
3.30e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 3.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1515 NIQKITHALNDIQNQQFELDLLIERSQEVL-RLADANNK-KTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEA 1592
Cdd:PRK03918 156 GLDDYENAYKNLGEVIKEIKRRIERLEKFIkRTENIEELiKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1593 QWSLIETKVtaiEEKGKLLDTVVRSKQHLYDTIKSLHELVTEAEKLKPMAAEVKALSGPVLAY--LAAFTEAPAHALEEk 1670
Cdd:PRK03918 236 LKEEIEELE---KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYikLSEFYEEYLDELRE- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1671 LNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERAsnlyifgpdqdateEELDELRWAVEQLLES 1750
Cdd:PRK03918 312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERH--------------ELYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1751 GKKFSGSTkaryqasqqlvPSDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLDEvqawIRQAELK--VQD 1828
Cdd:PRK03918 378 KKRLTGLT-----------PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE----LKKAKGKcpVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1829 RSIEPVPLKDQLRQVQEELGTITDKLERLTRNGRTIAENTRDDTEKQLIDSTVHNVTEQLNQVRNWLDERKQVVADTIDA 1908
Cdd:PRK03918 443 RELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEK 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1909 -WQRFLSLYEAVRTWTEEKRQFLVEPLKLSTLVQARQRLHeystavKSCKQINKNLSDMGKELESIGqVCSVGDLPEKLL 1987
Cdd:PRK03918 523 kAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE------KKLDELEEELAELLKELEELG-FESVEELEERLK 595
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 1988 EAEEAK------VQVEGQLLERNALLQETSEEWEQCERKMKEVKTWIEKAKQSLE 2036
Cdd:PRK03918 596 ELEPFYneylelKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
9713-9912 |
3.33e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 46.28 E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 9713 LWRRFEKQLEMVQQSVQEAdyMMELLTVQGSVDYDRLLKATERLEGLSGDLGAREVLIGELREAAEPLREGCAAEVrEKV 9792
Cdd:cd00176 1 KLQQFLRDADELEAWLSEK--EELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDA-EEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 9793 EAAVNEAVQAWEDTRAELDALCTKYQHACRLWQQYKDSSaAVKAWVDTQMDSVANLPP-------EEAVKHIKVCEETMA 9865
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLgkdlesvEELLKKHKELEEELE 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 373194212 9866 EHKERLAELQGLVAQIASDVGLDASGPLHCEVEALGQRLEDIRETLS 9912
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAE 203
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
212-303 |
3.61e-04 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 43.85 E-value: 3.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:pfam00435 13 LESWIEEKEALLSS-EDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEEiqERLEELNERWEQ 91
|
90
....*....|....
gi 373194212 290 LSENVDERKRLIEN 303
Cdd:pfam00435 92 LLELAAERKQKLEE 105
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
5569-5994 |
5.15e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 5.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5569 TQEKIAEKSKIETKEQSSVKKNKKSKKGKSDKDQSKHEFKDKEQDKQIDNAQTTEVELKLKDEITKESEIKDQEEA---K 5645
Cdd:TIGR04523 231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwnK 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5646 ENISEIKSKEIQEKSNENIFDNESEL---LQETKSDKSMQSEKRKKKSKERKVEIAPKQV-IETFIEENKVLESEIQKEI 5721
Cdd:TIGR04523 311 ELKSELKNQEKKLEEIQNQISQNNKIisqLNEQISQLKKELTNSESENSEKQRELEEKQNeIEKLKKENQSYKQEIKNLE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5722 LKEQSEAKDIQDIKATTELVQETIYEKPTSsgkrKGKSKEKKKAITTEIAIKEKEVSRPEIKEILKKESDIEEIKEIEEI 5801
Cdd:TIGR04523 391 SQINDLESKIQNQEKLNQQKDEQIKKLQQE----KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5802 EEKLKTIMKSEDEYKSE---IVQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISL---------EQ 5869
Cdd:TIGR04523 467 ETQLKVLSRSINKIKQNleqKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEkeskisdleDE 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5870 IIEISIEKNKPEIKGKISEKELEIEEdkeiQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKSKETKIETISEQITKI 5949
Cdd:TIGR04523 547 LNKDDFELKKENLEKEIDEKNKEIEE----LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA 622
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 373194212 5950 SIDEKKLSEFEAKEEISSQIKEEEI--IKQKRDDTDHTKQDITKENE 5994
Cdd:TIGR04523 623 KKENEKLSSIIKNIKSKKNKLKQEVkqIKETIKEIRNKWPEIIKKIK 669
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
850-953 |
7.30e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 43.09 E-value: 7.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 850 RKFEADLERARSWIKSKSNNLKKLSgyLPLKASKVEQDIVQHGELETDIDSFSEKdLNDILKQGNNLLKEcSEEDRARLN 929
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASED--LGKDLESVEALLKKHEAFEAELEAHEER-VEALNELGEQLIEE-GHPDAEEIE 76
|
90 100
....*....|....*....|....
gi 373194212 930 KILDELNKDYEELKSEAQEKQAAL 953
Cdd:smart00150 77 ERLEELNERWEELKELAEERRQKL 100
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1777-2060 |
1.64e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1777 LTALELCAEATAQAMEEKQREQKrartvrsdyltdLDEVQAWIRQAELKVQDrsiepvpLKDQLRQVQEELGTITDKLER 1856
Cdd:COG4942 6 LLALLLALAAAAQADAAAEAEAE------------LEQLQQEIAELEKELAA-------LKKEEKALLKQLAALERRIAA 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1857 LTRNGRTIaENTRDDTEKQLIDstvhnVTEQLNQVRNWLDERKQVVADTIDAWQRfLSLYEAVrtwteekrQFLVEPLKL 1936
Cdd:COG4942 67 LARRIRAL-EQELAALEAELAE-----LEKEIAELRAELEAQKEELAELLRALYR-LGRQPPL--------ALLLSPEDF 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1937 STLVQARQRLheystavkscKQINKNLSDMGKELEsigqvcsvgdlpEKLLEAEEAKVQVEGQLLERNALLQETSEEWEQ 2016
Cdd:COG4942 132 LDAVRRLQYL----------KYLAPARREQAEELR------------ADLAELAALRAELEAERAELEALLAELEEERAA 189
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 373194212 2017 CERKMKEVKTWIEKAKQSLESPQNKKKPLRDQHSIREKMLSDIA 2060
Cdd:COG4942 190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
212-302 |
2.47e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:smart00150 10 LEAWLEEKEQLLAS-EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEieERLEELNERWEE 88
|
90
....*....|...
gi 373194212 290 LSENVDERKRLIE 302
Cdd:smart00150 89 LKELAEERRQKLE 101
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
4512-5279 |
3.17e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4512 EESESTNPEINKEIIQIYEEEKLPIELKELEEVIPTSVEESKLTDVEVKSPIKSEELEVKNEKVTLSSGEESKPIEVEIK 4591
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4592 KEIIEIYEGEKPTLKLEEDKKIINIEKDTMKVIEEVTTEIKSTDRILDQTAALIEDLTKELDMIKKEEEQNKIVTIVEER 4671
Cdd:pfam02463 256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4672 KKESEAEKKEQVSEKKSKTEKSKKEKQSKSEKSKDKKKEISIKEHEVIEEKDIVETEMTQIIEQLTEIKKEESKETPLLI 4751
Cdd:pfam02463 336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4752 KELEEKDTTETAELSQIMEQLTAEIKKkeieeisllpKESEVIEKKDIDIIETSELTRTMEELITAIKEISTDEIIDQTE 4831
Cdd:pfam02463 416 QLEDLLKEEKKEELEILEEEEESIELK----------QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4832 EKKMEKNITEELLTTSQSKTEEEVKpamessKIERVGKETKSEKNKKKQKKQNEKKEETPVLENPIMTEQENIKKIVEKS 4911
Cdd:pfam02463 486 LELLLSRQKLEERSQKESKARSGLK------VLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4912 VSEKKKTSKESKKKEVKEASKEEKIITEEPVKSYPLEKDINIVT--------EITETEKLVNGKAIEIIDLDAIQSSTNQ 4983
Cdd:pfam02463 560 VEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILnlaqldkaTLEADEDDKRAKVVEGILKDTELTKLKE 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4984 QSSKEGKTKPVEKSKKEETKTKSGKQKQFKEKPDIKPKSTSDKELKKQDKQENSSPDSKKKREGKSKKTNDIPTPVSQEI 5063
Cdd:pfam02463 640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5064 VNEISSEEFKKEENQIEIKQASQEEIQPSVCTKSWASIVSM-KGNTETNNSTDISKVIPEESISETLKLEKIEKVEEIVP 5142
Cdd:pfam02463 720 EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEeKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5143 EELQNSPAHQKRMKHQKKKDAKQEKNVTEIKVSSTNTENEGEKEITIEESQELITKDSNKSYAQVAASNKRTSPQFNQED 5222
Cdd:pfam02463 800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5223 IIIAKPTPIMLNE---NTEKKEIAQEEALIITEIENVKEETIKSEKEVTMDKKFDELVIE 5279
Cdd:pfam02463 880 EEQKLKDELESKEekeKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
705-1094 |
3.63e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 705 SQQIEEQIKSVERRYADIGKKLQRKAQVLDMTA---QGIEATRQEIEENRDWIQQKKKQAQMSEPvgfDSKQAEERLLAL 781
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELReelEKLEKEVKELEELKEEIEELEKELESLEG---SKRKLEEKIREL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 782 KAMLKEAEGKqmvIDTLEKRVGnmqnelESNEQQQLENETKALRGEQSQLctiltegissatvaADARRKFEADLERARS 861
Cdd:PRK03918 265 EERIEELKKE---IEELEEKVK------ELKELKEKAEEYIKLSEFYEEY--------------LDELREIEKRLSRLEE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 862 WIKSKSNNLKKLSGylplKASKVEQDIVQHGELETDIDSFSEK-----DLNDILKQGNNLLKECSEEDRARLNKILDELN 936
Cdd:PRK03918 322 EINGIEERIKELEE----KEERLEELKKKLKELEKRLEELEERhelyeEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 937 KDYEELKSEAQEKQAALADLLQGRKAFESEIDK----------CQRWINEAEVATSSDVRTSSIDILREQLAKYDRLKKE 1006
Cdd:PRK03918 398 KAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1007 ANEYADDIEKLMQQGKSILPTVTDADKL-ELNEQLQNMK----EAHGRVAGIINERALALQKNIDEAEESLARVAEAIQY 1081
Cdd:PRK03918 478 LRKELRELEKVLKKESELIKLKELAEQLkELEEKLKKYNleelEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKK 557
|
410
....*....|...
gi 373194212 1082 MTDVQKELHELNK 1094
Cdd:PRK03918 558 LAELEKKLDELEE 570
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
2708-2894 |
4.66e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 44.70 E-value: 4.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2708 QPVEQPVQPISPATPSESTPMKTKIITE--------NKTFSYAQILSQGLAPKPSSAVSSYSPPTSVPsTTLVSKQVKER 2779
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSETPKTAVSEEatvqkdttSQPTKVEEVASEKNGAEQSSATPNDTTNAQQP-TVGAEKSAQEQ 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2780 SYSPVNSTTSSVHETS--PPQEARQTRESSVSKQESNWDITK-----KRETRKTHQEAPKTKIPEKRARRGSEYSKE--K 2850
Cdd:NF033875 128 PVVSPETTNEPLGQPTevAPAENEANKSTSIPKEFETPDVDKavdeaKKDPNITVVEKPAEDLGNVSSKDLAAKEKEvdQ 207
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 373194212 2851 LQKEKIKiNMEQQKQVFETKDEIVVEDTSKINVKNNEVEIKKEK 2894
Cdd:NF033875 208 LQKEQAK-KIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEK 250
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
10095-10455 |
5.74e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 5.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10095 NQHNETLAKIMERHAAVRDRLAAWDRYKLDQSKLLYW---LKEIERERSQLRFRFIQIQRLDEILQRIESLLEKIPEGEA 10171
Cdd:COG4717 91 AELQEELEELEEELEELEAELEELREELEKLEKLLQLlplYQELEALEAELAELPERLEELEERLEELRELEEELEELEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10172 QLESLQRQQETLLVKCDEALAVTIH---RDHAASVQRINNLSSSLEMWRDHIPRIQKRYKEYEEKaKEINSSFTEIGQAF 10248
Cdd:COG4717 171 ELAELQEELEELLEQLSLATEEELQdlaEELEELQQRLAELEEELEEAQEELEELEEELEQLENE-LEAAALEERLKEAR 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10249 STAF-HSSPASLTRTKQQLESVHQMQNRLSSMSVDLESLGVMIQQLREDLSPTDIKSLNEQRALFRLQHEDLEHQAALL- 10326
Cdd:COG4717 250 LLLLiAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALg 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10327 ------ICRLEERCGLYDRWRDRLARLLAWigETEIRIQDCDSPN---------EPEETLKKLECEIQSDIALKQRellw 10391
Cdd:COG4717 330 lppdlsPEELLELLDRIEELQELLREAEEL--EEELQLEELEQEIaallaeagvEDEEELRAALEQAEEYQELKEE---- 403
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 373194212 10392 IQNTGQDLVEVAEEEESERLQRSLDELNERWDRLVAMGKARASKLMDLMRTMSTLEKRINELRS 10455
Cdd:COG4717 404 LEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2793-3404 |
2.28e-28 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 128.34 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2793 ETSPPQEARQTRESSVSKQESNWDITKKRETRKTHQEAPKTKIPEKRARRGSEYSKEKLQKEKIKINMEQQKQVFETKDE 2872
Cdd:PTZ00121 1192 ELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAA 1271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2873 IVVEDTSKINVKNNEVEIKKEKVEDVQPEKRVDVEKTKKI-EAQKQDE-KQEIQEEKHDVQQRSRSQEKKRKGKKKKPEk 2950
Cdd:PTZ00121 1272 IKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAAEAAKA- 1350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2951 smddEIDKALKEIEDMDKQKKRD--KSREQTKIKDTTQTVQTEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAmnQ 3028
Cdd:PTZ00121 1351 ----EAEAAADEAEAAEEKAEAAekKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA--K 1424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3029 ANAKEQMKSKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIKiDSSSEMRKIETKEEKAQ--KDSANLSK 3106
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEeaKKKADEAK 1503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3107 KKQKGKEQTGTVK---DKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKS 3183
Cdd:PTZ00121 1504 KAAEAKKKADEAKkaeEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA 1583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3184 EKISetKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKqsQQKEEKKTEQSKQKKSVEKSEVIDIKLEEnEK 3263
Cdd:PTZ00121 1584 EEAK--KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK--AEEEKKKVEQLKKKEAEEKKKAEELKKAE-EE 1658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3264 IKIEIDVKAPKDEKEKKitgKEKEKKSESKDRKKKdikpEVALKEKAKEEQKAiinplinaiESDKKIEEKEIDN----- 3338
Cdd:PTZ00121 1659 NKIKAAEEAKKAEEDKK---KAEEAKKAEEDEKKA----AEALKKEAEEAKKA---------EELKKKEAEEKKKaeelk 1722
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 373194212 3339 KDSKESSTPKKEMKKAGEAEKQIKTKGGKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEK 3404
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
|
|
| KASH |
pfam10541 |
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS ... |
11199-11256 |
1.06e-27 |
|
Nuclear envelope localization domain; The KASH (for Klarsicht/ANC-1/Syne-1 homology) or KLS domain is a highly hydrophobic nuclear envelope localization domain of approximately 60 amino acids comprising a 20-amino-acid transmembrane region and a 30-35-residue C-terminal region that lies between the inner and the outer nuclear membranes. During meiotic prophase, telomeres cluster to form a bouquet arrangement of chromosomes. SUN and KASH domain proteins form complexes that span both membranes of the nuclear envelope. The KASH domain links the dynein motor complex of the microtubules, through the outer nuclear membrane to the Sad1 domain in the inner nuclear membrane which then interacts with the bouquet proteins Bqt1 and Bqt2 that are complexed with Bqt4, Rap1 and Taz1 and attached to the telomere. SUN domain-containing proteins are essential for recruiting KASH domain proteins at the outer nuclear membrane, and KASH domains provide a generic NE tethering device for functionally distinct proteins whose cytoplasmic domains mediate nuclear positioning, maintain physical connections with other cellular organelles, and possibly even influence chromosome dynamics.
Pssm-ID: 463142 Cd Length: 58 Bit Score: 109.22 E-value: 1.06e-27
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 11199 FLGRVLRVSLPIQALMLLFLGVASLVPSAEEDYSCMLSNNLARSFTPMVVYPNGPPPI 11256
Cdd:pfam10541 1 FLGRVLRAALPLQLLLLLLLLLACLLPAGEEDYSCTLANNFARSFHPMLRYVNGPPPT 58
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2798-3352 |
3.50e-26 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 121.40 E-value: 3.50e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2798 QEARQTRESS--VSKQESNWDITKKRETRKTHQEAPKTKIPEKRARRGSEYSK--EKLQKEKIKINMEQQKqvfetkdei 2873
Cdd:PTZ00121 1233 EEAKKDAEEAkkAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKaeEKKKADEAKKAEEKKK--------- 1303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2874 vVEDTSKINVKNNEVEIKKEKVEDVQpeKRVDVEKTKKIEAQKQDEKQEIQEEKHDVQQRSRSQEKKRKGKKKKPEKSMD 2953
Cdd:PTZ00121 1304 -ADEAKKKAEEAKKADEAKKKAEEAK--KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA 1380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2954 DEIDKALKEIEDMDKQKKrdKSREQTKIKDTTQTVQTEKYKEDIEKKGVKPGEKKKQNKSKMEKIR--DESEIAMNQANA 3031
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKK--KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEAKK 1458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3032 KEQMKSKNDTKESKEE--KNIEKRNAKDEAKISKEKVESRKNESEKRSEIKiDSSSEMRKIETK---------EEKAQKD 3100
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEakKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK-KKADEAKKAEEAkkadeakkaEEAKKAD 1537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3101 SANLSKKKQKGKE--QTGTVKDKSNKDSVKSTKTENESEQM--KKAIFIEDKTEIQKEKDIKPVENIGNL--DQLQKQED 3174
Cdd:PTZ00121 1538 EAKKAEEKKKADElkKAEELKKAEEKKKAEEAKKAEEDKNMalRKAEEAKKAEEARIEEVMKLYEEEKKMkaEEAKKAEE 1617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3175 TKsvklMKSEKISETKVESKEKEPAKPKEQDKSKKNKKQKQGTE-NEVSKDQTPKKQSQQK-----------EEKKTEQS 3242
Cdd:PTZ00121 1618 AK----IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEeNKIKAAEEAKKAEEDKkkaeeakkaeeDEKKAAEA 1693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3243 KQKKSVEKSEVIDIKLEENEKIKIEIDVKapKDEKEKKITGKEKEKKSESKDRKKKDIKPEVALKEKAKEEQKAIINPLI 3322
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEELK--KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
|
570 580 590
....*....|....*....|....*....|
gi 373194212 3323 NAIESDKKIEEKEIDNKDSKESSTPKKEMK 3352
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2813-3570 |
3.03e-24 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 114.85 E-value: 3.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2813 SNWDITKKRETRKTHQEAPKTKIPEKRARRGSE------YSKEKLQKEKIKINMEQQKQVFETKDEIVVEDTSKINVKNN 2886
Cdd:PTZ00121 1037 NNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDeglkpsYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARK 1116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2887 EVEIKKEKVEDVQPEKRVDVEKTKKIEAQKQDEKQEIQEEKHDVQQRSRSQEKKRKGKKKKPEKSMDDEIDKALKEIEDM 2966
Cdd:PTZ00121 1117 AEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKA 1196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2967 DKQKKRDKSREQTKIKDTTQTVQTEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKE 3046
Cdd:PTZ00121 1197 EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE 1276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3047 EKNIEKRNAKDEAKISKekvESRKNESEKRSEIKIDSSSEMRKIETKEEKAQ--KDSANLSKKK---QKGKEQTGTVKDK 3121
Cdd:PTZ00121 1277 ARKADELKKAEEKKKAD---EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEeaKKKADAAKKKaeeAKKAAEAAKAEAE 1353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3122 SNKDSVKSTKTENESEQMKKAifiEDKTEIQKEKdiKPVENIGNLDQLQK--QEDTKSVKLMKSEKISETKVESKEKEPA 3199
Cdd:PTZ00121 1354 AAADEAEAAEEKAEAAEKKKE---EAKKKADAAK--KKAEEKKKADEAKKkaEEDKKKADELKKAAAAKKKADEAKKKAE 1428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3200 KPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQK---EEKKTEQSKQKKSVEKSEVIDIKLEENEKIKIEIDVKAPKDE 3276
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3277 KEKKITGKEKEKKSESKDRKKKDIKPEVALKEKAKEEQKAiinPLINAIESDKKIEEKEIDNKDSKESSTPKKEMKKAGE 3356
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKA---DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3357 AeKQIKTKGGKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEKIIIEESKKEHLKLESVVPNTEQSEMKKHKKSK 3436
Cdd:PTZ00121 1586 A-KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3437 SPKRGKKEENLKFVEKEKTEKKETQGE--TIKLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQTD 3514
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEAKKAEEDEKKAAeaLKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 373194212 3515 KIEiQSAIEKIPEKIIVEGSMETFTETVEIAKETEKVKVSDTKEERETPLSEISKT 3570
Cdd:PTZ00121 1745 KAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
850-1062 |
1.16e-14 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 77.10 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 850 RKFEADLERARSWIKSKSNNLKklSGYLPLKASKVEQDIVQHGELETDIDSFSEKdLNDILKQGNNLLKECSEeDRARLN 929
Cdd:cd00176 3 QQFLRDADELEAWLSEKEELLS--STDYGDDLESVEALLKKHEALEAELAAHEER-VEALNELGEQLIEEGHP-DAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 930 KILDELNKDYEELKSEAQEKQAALADLLQGRKAFEsEIDKCQRWINEAEVATSSDVRTSSIDILREQLAKYDRLKKEANE 1009
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 1010 YADDIEKLMQQGKSILPTVTDADKLELNEQLQNMKEAHGRVAGIINERALALQ 1062
Cdd:cd00176 158 HEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLE 210
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
5604-6485 |
7.38e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.57 E-value: 7.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5604 KHEFKDKEQDKQIDNA--QTTEVELKLKDEITKESEIKDQEEAKENISEIKSKEIQEKSNENIFDNESELLQETKSDKSM 5681
Cdd:PTZ00121 1073 KPSYKDFDFDAKEDNRadEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAK 1152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5682 QSEKRKKKSKERKVEIAPKQvietfiEENKVLESEIQKEILKEQSEAKDIQDIKATTELVQETIYEKPTSSGKRKGKSKE 5761
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKA------EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA 1226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5762 KKKAITTEIAIKEKEVSRPEikEILKKESDIEEIKEIEEIEEKLKTIMKSEDEYKSEIVQETKS-KKSEFSEKNKEKSKE 5840
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKA 1304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5841 EEITKISIEKKKLPELKIKENTAEISLEQIIEISIEKNKPEIKGKISEKELEIEEDKEIQKEVQTSIKCEIENKPEVVQE 5920
Cdd:PTZ00121 1305 DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5921 TKFEKSPKKRKGKSKETKIETISEQITKISIDEKKLSEFEAKEEISSQIKEEEIIKQKRDDTDHTKQDITKENEIETFTI 6000
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6001 TSEKLKEKENSIKESTElsqtiAREISDSKIETIEEKKEIKIEQTTEiEDKSKVSKKEKRKQKRKEKSATRAtsQEKLKN 6080
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEE-----AKKADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKA--EEAKKA 1536
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6081 EKSEAISQEQKGEiniVSKTSDELKTEEisteiiltnenkEKKDTNEISKEIEKLILSEVIPDEIKLVPETMPIPIPKEE 6160
Cdd:PTZ00121 1537 DEAKKAEEKKKAD---ELKKAEELKKAE------------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6161 IKIIKEKIELSKSIEEQEIISDEIKLVPET--LSISISKEEIKPIKEIAEFPKPTEEKKVVSDKIKLEtivipisediSE 6238
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK----------AE 1671
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6239 NSIKEKTELPKPKQNEISDEIKLVPESlsisiskEEIQPIKEIIELSKSIEEKEEIINKTKDIVEEKGEIIKPMIDKDKK 6318
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEA-------EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6319 QEESSFKKSKRKNKQAKKIKHEEA-------------ETEIKSADE------DLLSSKIEKNIEILSTGSS--TPSPDTP 6377
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKkaeeirkekeaviEEELDEEDEkrrmevDKKIKDIFDNFANIIEGGKegNLVINDS 1824
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6378 KDIFQIEEKILNVTIPEQKIEVIDI-----LTIDEIKKDEKEIKNTTEQKIIFEEEKTLSKTQEEIEEINLQKIEEIPST 6452
Cdd:PTZ00121 1825 KEMEDSAIKEVADSKNMQLEEADAFekhkfNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPN 1904
|
890 900 910
....*....|....*....|....*....|...
gi 373194212 6453 SPIKKKVMKEDKSKNDDKEIHEIKSLTTEEKIV 6485
Cdd:PTZ00121 1905 NNMAGKNNDIIDDKLDKDEYIKRDAEETREEII 1937
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2983-3684 |
3.69e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 78.26 E-value: 3.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2983 DTTQTVQTEKYKEDIEKKGVKPGEKKKQ-NKSKMEKIRDESEIAMNQANAKEQMK-SKNDTKESKEEKNIEKRNAKDEAK 3060
Cdd:PTZ00121 1019 DFNQNFNIEKIEELTEYGNNDDVLKEKDiIDEDIDGNHEGKAEAKAHVGQDEGLKpSYKDFDFDAKEDNRADEATEEAFG 1098
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3061 ISKE--KVESRKNESEKRSEIKIDSSSEMRKIET--KEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSVKSTKTENES 3136
Cdd:PTZ00121 1099 KAEEakKTETGKAEEARKAEEAKKKAEDARKAEEarKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKA 1178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3137 EQMKKAIFIEDKTEIQKEKDIKPVE------NIGNLDQLQKQEDTKSVK-LMKSEKISETKVESKEKEPAKPKEQDKSKK 3209
Cdd:PTZ00121 1179 EAARKAEEVRKAEELRKAEDARKAEaarkaeEERKAEEARKAEDAKKAEaVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3210 NKKQKQGTENEVSKDQTPKKQSQQ----KEEKKTEQSKQKKSVEKSEVIDIKLEENEKI----KIEIDVKAPKDEKEKKI 3281
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADElkkaEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeakKKAEEAKKKADAAKKKA 1338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3282 TGKEKEKKSESKDRKKKDIKPEVAlKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKESSTPKK---EMKKAGEAE 3358
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAA-EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKkadELKKAAAAK 1417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3359 KQiktkggkkskkeADINQKPATEIIKKEEtiivdkqiIEEKIDEKIIIEESKK---EHLKLESVVPNTEQSEMKKHKKS 3435
Cdd:PTZ00121 1418 KK------------ADEAKKKAEEKKKADE--------AKKKAEEAKKADEAKKkaeEAKKAEEAKKKAEEAKKADEAKK 1477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3436 KSPKRGKKEENLKfvekektekketqgetiKLEEISDKIDNTKEKSIKEIKEEIvievkeeisAIQVEEKKEKDimqtdk 3515
Cdd:PTZ00121 1478 KAEEAKKADEAKK-----------------KAEEAKKKADEAKKAAEAKKKADE---------AKKAEEAKKAD------ 1525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3516 iEIQSAIEKipekiiveGSMETFTETVEIAKETEKVKVSDTKEERETPLSEISKTEELEDQQPEQKSEMPSTLKNKKSNK 3595
Cdd:PTZ00121 1526 -EAKKAEEA--------KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3596 SKEKHPIEKVTPLSIVQEPKPNTSKSQPSTPKSDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKSIEESIEIPDVAS 3675
Cdd:PTZ00121 1597 VMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676
|
....*....
gi 373194212 3676 EKSIFKEKE 3684
Cdd:PTZ00121 1677 AEEAKKAEE 1685
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2812-3711 |
1.01e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 73.08 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2812 ESNWDITKKRETRKTHQEApktkipEKRARRGSEYSKEKLQKEKIKINMEQQKQVFETKDEIVVEDTSKINVKNNEVEIK 2891
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEET------ENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2892 KEKVEDVQPEKRVDVEKTKKIEAQKQDEKQEIQEEKHDVQQRSRSQEKkrkgkkkkpeksmddEIDKALKEIEDMDKQKK 2971
Cdd:pfam02463 238 RIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE---------------EELKLLAKEEEELKSEL 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2972 RDKSREQTKIKDTTQTVQTEKYKEDIEKKgvkpgeKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIE 3051
Cdd:pfam02463 303 LKLERRKVDDEEKLKESEKEKKKAEKELK------KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELL 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3052 KRNAKDEAKISKEKVESRKNESEKRSEIKIDSS----SEMRKIETKEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSV 3127
Cdd:pfam02463 377 AKKKLESERLSSAAKLKEEELELKSEEEKEAQLllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQ 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3128 KSTKTENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKSEKISETKVESKEKEPAKPKEQDKS 3207
Cdd:pfam02463 457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3208 KKNKKQKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEK--IKIEIDVKAPKDEKEKKITGKE 3285
Cdd:pfam02463 537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKsiAVLEIDPILNLAQLDKATLEAD 616
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3286 KEKKSESKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDskesstpkKEMKKAGEAEKQIKTKG 3365
Cdd:pfam02463 617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL--------TKELLEIQELQEKAESE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3366 GKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEKIIIEESKKEHLKLEsvvpNTEQSEMKKHKKSKSPKRGKKEE 3445
Cdd:pfam02463 689 LAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL----KQKIDEEEEEEEKSRLKKEEKEE 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3446 NLKFVEKEKTEKKETQGETIKLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQTDKIEIQSAIEKI 3525
Cdd:pfam02463 765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKE 844
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3526 PEKIIVEGSMETFTETVEIAKETEKVKVSDTKEEretplsEISKTEELEDQQPEQKSEMPSTLKNKKSNKSKEKHPIEKV 3605
Cdd:pfam02463 845 EQKLEKLAEEELERLEEEITKEELLQELLLKEEE------LEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3606 TPLSIVQEPKPNTsksqpstpksDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKSIEESIEIPDVASEKSIFKEKEI 3685
Cdd:pfam02463 919 IEERIKEEAEILL----------KYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEE 988
|
890 900
....*....|....*....|....*.
gi 373194212 3686 STTLQPEIIPIIESEKDQIIEIDESK 3711
Cdd:pfam02463 989 RYNKDELEKERLEEEKKKLIRAIIEE 1014
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2836-3710 |
1.65e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 72.70 E-value: 1.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2836 PEKRARRGSEYSKEKLQKEKIKINMEQQKQVFETKDEIVVEDTSKINVKNNEVEIKKEKVEDVQPEKRVDVEKTKKIEAQ 2915
Cdd:pfam02463 151 KPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLD 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2916 KQDEKQEIQEEKHDVQQRSRSQEKKRKGKKKKPEKSMDD---EIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEK 2992
Cdd:pfam02463 231 YLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQvlkENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKV 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2993 YKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAMNQANAKEQmksKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKNE 3072
Cdd:pfam02463 311 DDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKRE---AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLS 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3073 SEKR----------SEIKIDSS----SEMRKIETKEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSVKSTKTENESEQ 3138
Cdd:pfam02463 388 SAAKlkeeelelksEEEKEAQLllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELEL 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3139 MKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKSEKISETKVESKEKEPAKPKEQDKSKKNKKQKQGTE 3218
Cdd:pfam02463 468 KKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIST 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3219 NEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEK--IKIEIDVKAPKDEKEKKITGKEKEKKSESKDRK 3296
Cdd:pfam02463 548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKsiAVLEIDPILNLAQLDKATLEADEDDKRAKVVEG 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3297 KKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKESSTPKKEMKKAGEAEKQIKTKGGKKSKKEADIN 3376
Cdd:pfam02463 628 ILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQR 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3377 QKPATEIIKKEETIIVDKQIIEEKIDEKIIIEESKKEHLKLESVVPNTEQSEMKKHKKSKSPKRGKKEENLKFVEKEKTE 3456
Cdd:pfam02463 708 EKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3457 KKETQGETIKLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQTDKIEIQSAIEKIPEKIIVEGSME 3536
Cdd:pfam02463 788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3537 TFTETVEIAKETEKVKVSDTKEERETPLSEISKTEELEDQQPEQK-SEMPSTLKNKKSNKSKEKHPIEKVTPLSIVQEPK 3615
Cdd:pfam02463 868 LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLeEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3616 PNTSKSQPSTPKSDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKSIEESIEIPDVASEKSIFKEKEISTTLQPEIIP 3695
Cdd:pfam02463 948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFV 1027
|
890
....*....|....*
gi 373194212 3696 IIESEKDQIIEIDES 3710
Cdd:pfam02463 1028 SINKGWNKVFFYLEL 1042
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
277-1089 |
6.51e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 6.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 277 LERTKELLKRWENLSENVDERKRLIENE---MQEYNAYHAALQETEKWLLQISFQlmAHNSLYITNKEQTVSQIQQHENL 353
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQaekAERYKELKAELRELELALLVLRLE--ELREELEELQEELKEAEEELEEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 354 LVEIENYTSVLNDLKL-------KGNGQITRYVAVNSEIKTIiETQLQNVQESYNSLLNTALQIKKRLAESLIKFQEYEN 426
Cdd:TIGR02168 259 TAELQELEEKLEELRLevseleeEIEELQKELYALANEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 427 TLESIMKNLDAYEPEIA---QEMEAPMDTLDAAKQRFENARMLHNKLQGEKTRLALAVEACEAAVACVSRPGSPLDAPPV 503
Cdd:TIGR02168 338 ELAELEEKLEELKEELEsleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 504 QIPAREVEVRNKLEEL-IDQAQGHLMNVTKALNELEEQTRQKNVLRAWINQQRALcAEWKSRPAKLRSEAALAELQAMND 582
Cdd:TIGR02168 418 RLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAERELAQLQARLDSLER 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 583 LLGNVgERRTHALTELSLHEDDQDIEEGL--------NKLEAELTDAIAGkqAAQDLIqkyrtqVQNMQSWLDTlskkVD 654
Cdd:TIGR02168 497 LQENL-EGFSEGVKALLKNQSGLSGILGVlselisvdEGYEAAIEAALGG--RLQAVV------VENLNAAKKA----IA 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 655 VIEKGNG---------QTIGQKIASVKEITTEFESQGPGKLNEVKTLSDQVMDSVSNL--------DSQQIEEQIKSVER 717
Cdd:TIGR02168 564 FLKQNELgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvdDLDNALELAKKLRP 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 718 RYADI---GKKLQRKAQVL---DMTAQGIEATRQEIEENRdwiqqkKKQAQMSEPVGFDSKQAEERLLALKAMLKEAEGK 791
Cdd:TIGR02168 644 GYRIVtldGDLVRPGGVITggsAKTNSSILERRREIEELE------EKIEELEEKIAELEKALAELRKELEELEEELEQL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 792 QMVIDTLEKRVGNMQNELE--SNEQQQLENETKALRGEQSQLCTILT------EGISSATVAADARR-KFEADLERARSW 862
Cdd:TIGR02168 718 RKELEELSRQISALRKDLArlEAEVEQLEERIAQLSKELTELEAEIEeleerlEEAEEELAEAEAEIeELEAQIEQLKEE 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 863 IKSKSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSfSEKDLNDILKQgnnllKECSEEDRARLNKILDELNKDYEEL 942
Cdd:TIGR02168 798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAA-TERRLEDLEEQ-----IEELSEDIESLAAEIEELEELIEEL 871
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 943 KSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEvatssdvrtssiDILREQLAKYDRLKKEANEYADDIEKLMQQGK 1022
Cdd:TIGR02168 872 ESELEALLNERASLEEALALLRSELEELSEELRELE------------SKRSELRRELEELREKLAQLELRLEGLEVRID 939
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1023 SILPTVTDADKLELNEQLQNM-------KEAHGRVA---------GIINERALA-----------LQKNIDEAEESLARV 1075
Cdd:TIGR02168 940 NLQERLSEEYSLTLEEAEALEnkieddeEEARRRLKrlenkikelGPVNLAAIEeyeelkerydfLTAQKEDLTEAKETL 1019
|
890
....*....|....
gi 373194212 1076 AEAIQYMTDVQKEL 1089
Cdd:TIGR02168 1020 EEAIEEIDREARER 1033
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
3867-4625 |
8.02e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.56 E-value: 8.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3867 FGSVQDRRKDRSGTPLSAKSVENAK----DEREVDDLKEGQGVdAKISQDTLGENEGKAEkgemmVKKEVNVFEKIE-SE 3941
Cdd:PTZ00121 1097 FGKAEEAKKTETGKAEEARKAEEAKkkaeDARKAEEARKAEDA-RKAEEARKAEDAKRVE-----IARKAEDARKAEeAR 1170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3942 RFKDSRELVVENEDKSVKEKQETNKTVEellftVGKGEDVKNAVEELLEAERQAMVVEQKIVDIEKGETVPVKLEDSKfK 4021
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEVRKAEELRKAED-----ARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAK-K 1244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4022 LEEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKVIEKGVEVPvDIKSVTKEIEGKITLPEEKVAE--FEK 4099
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAK-KAEEKKKADEAKKKAEEAKKADeaKKK 1323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4100 SIEVPIKINDTKLETEEIKLEDKVDSEKQERI--EIEDFKSIMKGIEDKTDLIEEKLIDTGKREDVSIKLKKIENKPTQD 4177
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAadEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4178 EEKIKEVpiniKDFESIIEKINSETILVEEKDLKEKIEIPLEIKSITEEVEDKTalfeekvvESEKSFKEVPVKIDYSKS 4257
Cdd:PTZ00121 1404 KKKADEL----KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA--------EEAKKAEEAKKKAEEAKK 1471
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4258 QEEIKVEEKIVEKQEtivnkDFKSKMENIEDKTILEENIIESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYY 4337
Cdd:PTZ00121 1472 ADEAKKKAEEAKKAD-----EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4338 FTDLVKpywfnyrpyiKAEidfyrhfkIVKILEENVPAPVLPRSDSIERIVQESIMKNSKEEEKKIESAEQSETEYTNAS 4417
Cdd:PTZ00121 1547 KADELK----------KAE--------ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4418 QEIIKeKSKETENKTKDTKESETEYKHVLQESIEEKSKKIEKKTEDIEESEAEYRKYALIgetfkypistfYKLESEWVK 4497
Cdd:PTZ00121 1609 AEEAK-KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA-----------KKAEEDKKK 1676
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4498 SKLIQEKEVTLIPVEESESTNPEINKEIIQIY----EEEKLPIELKELEEVIPTSVEESKLTDVEVKSpiKSEELEV--- 4570
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKkkeaEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK--KAEEAKKdee 1754
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 4571 -KNEKVTLSSGEESKPIEVEIKKE--IIEIYEGEKPTLKLEEDKKIINIEKDTMKVIE 4625
Cdd:PTZ00121 1755 eKKKIAHLKKEEEKKAEEIRKEKEavIEEELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
5551-6347 |
2.33e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 68.84 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5551 QTIEFEALEADKIMEVNGTQEKIAEKSKIETKEQSSVKKNKKSKKGKSDKDQSKHEFKDKEQDKQIDNAQTTEVELKLKD 5630
Cdd:pfam02463 265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5631 EITKESEIKDQEEAKENISEIKSKEIQEKSNENIFDNESELLQETKSDKSMQSEKRKKKSKERKVEIAPKQVIETFIEEN 5710
Cdd:pfam02463 345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5711 KVLESEIQKEILKEQSEAKDIQDIKATTELVQETIYEKptssgkrKGKSKEKKKAITTEIAIKEKEVSRPEIKEILKKES 5790
Cdd:pfam02463 425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLK-------DELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5791 DIEEIKEIEEIEEKLKTIMKSEDEYKSEIVQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISLEQI 5870
Cdd:pfam02463 498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5871 IEISIEKNKPEIKGKISEKELEIEEDKEIQKEvqtsikceiENKPEVVQETKFEKSPKKRKGKSKETKieTISEQITKIS 5950
Cdd:pfam02463 578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD---------KATLEADEDDKRAKVVEGILKDTELTK--LKESAKAKES 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5951 IDEKKLSEFEAKEEISSQIKEEEIIKQKRDDTDHTKQDITKENEIETFTITSEKLKEKENSIKESTELSQTIAREISDSK 6030
Cdd:pfam02463 647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6031 IETIEEKKeikieqttEIEDKSKVSKKEKRKQKRKEKSATRATSQEKLKNEKSEAISQEQKGEINIVSKTSDELKTEEIS 6110
Cdd:pfam02463 727 VQEAQDKI--------NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6111 TEIILTNENKEKKDTNEISKEIEKLILSEVIPDEiklvpETMPIPIPKEEIKIIKEKIELSKSIEEQEIISDEIKLVPET 6190
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKE-----EELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELL 873
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6191 LSISISKEEIKPIKEIAEfpkptEEKKVVSDKIKLETIVIPISEDISENSIKEKTELPKPKQNEISDEIKlvpeslsisi 6270
Cdd:pfam02463 874 LKEEELEEQKLKDELESK-----EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPE---------- 938
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 6271 sKEEIQPIKEIIELSKSIEEKEEIINKTKDIVEEKGEIIKPMI-DKDKKQEESSFKKSKRKNKQAKKIKHEEAETEIK 6347
Cdd:pfam02463 939 -ELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIeEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10930-11117 |
3.85e-10 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 64.00 E-value: 3.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10930 WAQLENDLWRLEKWLEFAEgTQSAQHSPPGNIEQLEDVIQDHREFVLDLDCHESILASLNTVGAHLADHTEEllRATQLR 11009
Cdd:cd00176 2 LQQFLRDADELEAWLSEKE-ELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP--DAEEIQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 11010 DRLAVANTRWVKVCKVAAHWQEQLQTALMSnEQFHRIIEELVTWLEKTEVSIRASEPVDlteSPEIMTAKYNKFRELRSD 11089
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDL-QQFFRDADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKELEEE 154
|
170 180
....*....|....*....|....*...
gi 373194212 11090 LERCEPRVLSLQESANQLLDEKGETRAR 11117
Cdd:cd00176 155 LEAHEPRLKSLNELAEELLEEGHPDADE 182
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10347-10546 |
8.50e-10 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 62.85 E-value: 8.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10347 LLAWIGETEIRIQDCDSPNEPEET---LKKLEcEIQSDIALKQRELLWIQNTGQDLVEVAEEEESeRLQRSLDELNERWD 10423
Cdd:cd00176 12 LEAWLSEKEELLSSTDYGDDLESVealLKKHE-ALEAELAAHEERVEALNELGEQLIEEGHPDAE-EIQERLEELNQRWE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10424 RLVAMGKARASKLMDLMRTMSTLEKrINELRSWLASVESQLSETFVVEAIEQscIDKKLDDHEHLQKTIEAESGNIGEVL 10503
Cdd:cd00176 90 ELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLES--VEELLKKHKELEEELEAHEPRLKSLN 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 373194212 10504 NLCEILLNDCDAwktSFNNAIKSGMEGLERRWTTTCVKSAERK 10546
Cdd:cd00176 167 ELAEELLEEGHP---DADEEIEEKLEELNERWEELLELAEERQ 206
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
5624-6483 |
9.19e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.09 E-value: 9.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5624 VELKLKDEITKESEIKDQEEAKENISEIKSKE---IQEKSNENIFDNESELLQETKSDKSMQSEKRKkkskerkVEIAPK 5700
Cdd:PTZ00121 1033 TEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAhvgQDEGLKPSYKDFDFDAKEDNRADEATEEAFGK-------AEEAKK 1105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5701 QVIETFIEENKVLESEIQKEILKEQSEAKDIQDIKATTEL-----VQETIYEKPTSSGKRKGKSKEKKKAITTEIAIKEK 5775
Cdd:PTZ00121 1106 TETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEArkaedAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE 1185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5776 EVSRPEikEILK-KESDIEEIKEIEEIEEKLKTIMKSEDEYKSEIVQETKSKKSEfseknkekskeeeitkisIEKKKLP 5854
Cdd:PTZ00121 1186 EVRKAE--ELRKaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD------------------AEEAKKA 1245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5855 ElKIKENTAEISLEQIIEISIEKNKPEIKGKISEKELEIEEDKEIQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKS 5934
Cdd:PTZ00121 1246 E-EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKA 1324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5935 KETKIEtiSEQITKISIDEKKLSEFEAKEEISSQIKEEEIIKQKRDDTDHTKQDITKeneietftitSEKLKEKENSIKE 6014
Cdd:PTZ00121 1325 EEAKKK--ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK----------ADAAKKKAEEKKK 1392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6015 STELSQTIAREISDSKIETIEEkkeikieqtteiEDKSKVSKKEKRKQKRKEKSATRATSQEKLKNEKSEAISQEQKGEI 6094
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAA------------AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAE 1460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6095 NIVSKTSDELKTEEisteiiLTNENKEKKDTNEISKEIEKlilSEVIPDEIKLVPETMPIPIPKEEIKIIKEKIELSKSI 6174
Cdd:PTZ00121 1461 EAKKKAEEAKKADE------AKKKAEEAKKADEAKKKAEE---AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6175 EEQEiiSDEIKLVPETLSisisKEEIKPIKEI--AEFPKPTEEKKVVSDKIKLETIVIPISEDISENSIKEKTELPKPKQ 6252
Cdd:PTZ00121 1532 EAKK--ADEAKKAEEKKK----ADELKKAEELkkAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6253 NEISDEIKLVPESLSISISKEEIQPIKEIIELSKSIEEKE----EIINKTKDIVEEKGEIIKPMIDKDKKQEESSFKKSK 6328
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkkaEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6329 RKNKQAKKIKHEEAETEIKSADEDLLSSKIEKNIEIlstgsstpspdtpkdifqieekilnvtipeQKIEVIDILTIDEI 6408
Cdd:PTZ00121 1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL------------------------------KKAEEENKIKAEEA 1735
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 6409 KKDEKEIKNTTEQKIIFEEEKtlsktqEEIEEINLQKIEEIPSTSPIKKKVMKEDKSKNDDKEIHEIKSLTTEEK 6483
Cdd:PTZ00121 1736 KKEAEEDKKKAEEAKKDEEEK------KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIF 1804
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
5812-6590 |
1.25e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.70 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5812 EDEYKSEIVQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISLEQIIEisiEKNKPEIKGKISE-KE 5890
Cdd:PTZ00121 1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE---DAKRVEIARKAEDaRK 1165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5891 LEIEEDKEIQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKSKETKIETISEqitkiSIDEKKLSEFEAKEEISSqiK 5970
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK-----AEDAKKAEAVKKAEEAKK--D 1238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5971 EEEiikQKRDDTDHTKQDITKENEIETFTITSEKLKEKENSIKESTELSQTIAREISDSKIETIEEKKEIKIEQTTEIED 6050
Cdd:PTZ00121 1239 AEE---AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6051 KSKVSKKEKRKQKRKEKSATRATSQEKLKNE--KSEAISQEQKGEINIVSKTSDELKTEEISTEI-ILTNENKEKKDTNE 6127
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAdAAKKKAEEKKKADE 1395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6128 ISK----------EIEKLILSEVIPDEIKL-VPETMPIPIPKEEIKIIKEKIELSKSIEEQEIISDEIKLVPETLSISIS 6196
Cdd:PTZ00121 1396 AKKkaeedkkkadELKKAAAAKKKADEAKKkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6197 KEEIKPIKEIAEFPKPTEEKKVVSDKIKLETIVIPISEDISENSIKEKT-ELPKPKQNEISDEIKLVPEslsisisKEEI 6275
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdEAKKAEEAKKADEAKKAEE-------KKKA 1548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6276 QPIKEIIELSKSiEEKEEIINKTKDivEEKGEIIKPMIDKDKKQEESSFKKSKRKNKQAKKIKHEEA--ETEIKSADEDL 6353
Cdd:PTZ00121 1549 DELKKAEELKKA-EEKKKAEEAKKA--EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAkkAEEAKIKAEEL 1625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6354 LSSKIEKNIEILSTGSSTPSPDTPKDIFQIEEKILNVTIPEQKIEVIDILTIDEIKKDEKEIKNTTEQKIIFEEEKTLSK 6433
Cdd:PTZ00121 1626 KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6434 TQEEIEEINLQKIEEIPSTSPIKKKVMKEDKSK--NDDKEIHEIKSLTTEEKIVHQTSEViedtiipfEVEKPIETIEST 6511
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEaeEDKKKAEEAKKDEEEKKKIAHLKKE--------EEKKAEEIRKEK 1777
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 373194212 6512 EVTINGILKEETDEIEKEIIKIeaTEEIYPEIvkeNIIQEIDKVPEQFIPIEKLLDEIESPIIIDSIESQLETEEEFEK 6590
Cdd:PTZ00121 1778 EAVIEEELDEEDEKRRMEVDKK--IKDIFDNF---ANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
507-1383 |
3.37e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 3.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 507 AREVEVRNKLEElidqAQGHLMNVTKALNELEEQ----TRQKNVLRAWINQQRALcAEWKSRPAKLRSEAALAELQAMND 582
Cdd:TIGR02168 172 ERRKETERKLER----TRENLDRLEDILNELERQlkslERQAEKAERYKELKAEL-RELELALLVLRLEELREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 583 LLGNVGERRthaltelslheddQDIEEGLNKLEAELTDAIAGKQAAQDLIQKYRTQVQNMQSWLDTLSKKVDVIEKgNGQ 662
Cdd:TIGR02168 247 ELKEAEEEL-------------EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLA 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 663 TIGQKIASVKEITTEFESqgpgKLNEVKTlsdqvmdsvsnlDSQQIEEQIKSVERRYADIGKKLQRKAQVLDMTAQGIEA 742
Cdd:TIGR02168 313 NLERQLEELEAQLEELES----KLDELAE------------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 743 TRQEIEENRDWIQQKKKQAqmsepvgfdsKQAEERLLALKAMLKEaegkqmvidtLEKRVGNMQNELESNEQQQLENETK 822
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQI----------ASLNNEIERLEARLER----------LEDRRERLQQEIEELLKKLEEAELK 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 823 ALRGEQSQLCTILTEgissatvAADARRKFEADLERARSWIKSKSNNLKKLSGYLPLKASKVE--QDIVQHGELETDIDS 900
Cdd:TIGR02168 437 ELQAELEELEEELEE-------LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVK 509
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 901 F---SEKDLNDILKQGNNLLkECSEEDRARLNKILDELNKDYE-ELKSEAQEKQAALADLLQGRKAF--ESEIDKCQRWI 974
Cdd:TIGR02168 510 AllkNQSGLSGILGVLSELI-SVDEGYEAAIEAALGGRLQAVVvENLNAAKKAIAFLKQNELGRVTFlpLDSIKGTEIQG 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 975 NEAEVATSSDVRTSSIDILREQLAKYDRlkkeANEY-------ADDIEKLMQQGKSILPT---VTDADKLELneqlqnmk 1044
Cdd:TIGR02168 589 NDREILKNIEGFLGVAKDLVKFDPKLRK----ALSYllggvlvVDDLDNALELAKKLRPGyriVTLDGDLVR-------- 656
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1045 eAHGRVAGIINERA---LALQKNIDEAEESLARVAEAIQYMTDVQKELHELNKPIGSRVEDVEAMLDAYERILNDLKANK 1121
Cdd:TIGR02168 657 -PGGVITGGSAKTNssiLERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1122 AKLSDLQ---SINVADLHGVLTQQDDLMKAIESQIAKLRQLLLLRQQFIA-LITEITTFIAKYTEIVRDIEN-SGQTTEE 1196
Cdd:TIGR02168 736 ARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEeLEAQIEQLKEELKALREALDElRAELTLL 815
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1197 KIkRYDDAILKIQECEATLASATDKGQQIAAEgstvdRNNITEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANEL 1276
Cdd:TIGR02168 816 NE-EAANLRERLESLERRIAATERRLEDLEEQ-----IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1277 AEILDWLEDKEKEVKsrpllerdpiSVEAELQKHNELCDAVNEHLDRIRNLKNSVpheEGMPGSLKEMLSEAVSLLTSLP 1356
Cdd:TIGR02168 890 ALLRSELEELSEELR----------ELESKRSELRRELEELREKLAQLELRLEGL---EVRIDNLQERLSEEYSLTLEEA 956
|
890 900
....*....|....*....|....*..
gi 373194212 1357 REMEErgNYLESNMKLRQEYAALTEKL 1383
Cdd:TIGR02168 957 EALEN--KIEDDEEEARRRLKRLENKI 981
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
212-418 |
1.29e-08 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 59.38 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDLpDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:cd00176 12 LEAWLSEKEELLSST-DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEiqERLEELNQRWEE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 290 LSENVDERKRLIENEMQEYNAYHAALQEtEKWLLQISFQLMAHNslYITNKEQTVSQIQQHENLLVEIENYTSVLNDLKL 369
Cdd:cd00176 91 LRELAEERRQRLEEALDLQQFFRDADDL-EQWLEEKEAALASED--LGKDLESVEELLKKHKELEEELEAHEPRLKSLNE 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 373194212 370 KGNGQITRyvaVNSEIKTIIETQLQNVQESYNSLLNTALQIKKRLAESL 418
Cdd:cd00176 168 LAEELLEE---GHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
991-1854 |
1.81e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.38 E-value: 1.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 991 DILREQLAKYDRLKKEAnEYADDIEKLMQQGKSILPTVTDADKLELNEQLQNMKEAHGRVAGIINEralaLQKNIDEAEE 1070
Cdd:TIGR02168 193 DILNELERQLKSLERQA-EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE----LTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1071 SL----ARVAEAIQYMTDVQKELHELNkpigSRVEDVEAMLDAYERILNDLKANKAKLSdlqsinvADLHGVLTQQDDLM 1146
Cdd:TIGR02168 268 KLeelrLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLEELE-------AQLEELESKLDELA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1147 KAIESQIAKLRQLLLLRQQFIALITEittFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIA 1226
Cdd:TIGR02168 337 EELAELEEKLEELKEELESLEAELEE---LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1227 AEGSTVDRNNITEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANELAEILDWLEDKEKEVKSRpllerdpisvEAE 1306
Cdd:TIGR02168 414 DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA----------ERE 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1307 LQKHNELCDAV----NEHLDRIRNLKNSVPHEEGMPGsLKEMLSEAVSLLTSLPREME----ERGNYL--ESNMKLRQEY 1376
Cdd:TIGR02168 484 LAQLQARLDSLerlqENLEGFSEGVKALLKNQSGLSG-ILGVLSELISVDEGYEAAIEaalgGRLQAVvvENLNAAKKAI 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1377 AALTEKLR--------SWVREAEI---RLESDKDGLDFENILSDLEEHKIYFSsePSI-----RELVSQQIQQA------ 1434
Cdd:TIGR02168 563 AFLKQNELgrvtflplDSIKGTEIqgnDREILKNIEGFLGVAKDLVKFDPKLR--KALsyllgGVLVVDDLDNAlelakk 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1435 -----------GDKIWPS--------------LNTS----EQEELSAEQQQHTQLLKNTLNTAKSQRARLEQGAETWRDY 1485
Cdd:TIGR02168 641 lrpgyrivtldGDLVRPGgvitggsaktnssiLERRreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1486 TQTLERvraviarsrftdEPVTTLAGLQFNIQKITHALNDIQNQQFEL-DLLIERSQEVLRLADAnnkktiEAQISEISA 1564
Cdd:TIGR02168 721 LEELSR------------QISALRKDLARLEAEVEQLEERIAQLSKELtELEAEIEELEERLEEA------EEELAEAEA 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1565 EWKELVSGLEGRRDALEALSKHWEDLEAQWSlietkvtaiEEKGKLLDTVVRSKQHLYDTIKSLHELVTEAEKLKPMAAE 1644
Cdd:TIGR02168 783 EIEELEAQIEQLKEELKALREALDELRAELT---------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1645 VKALSGPVLAYlaaftEAPAHALEEKLNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLy 1724
Cdd:TIGR02168 854 IESLAAEIEEL-----EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL- 927
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1725 ifgpdqdatEEELDELRWAVEQLLEsgkKFSGSTKARYQASQQLVPSDLAQHLTALELCAEATAQ----------AMEEK 1794
Cdd:TIGR02168 928 ---------ELRLEGLEVRIDNLQE---RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKikelgpvnlaAIEEY 995
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1795 QREQKRARTVRSDYlTDLDEVQAWIRQAELKVQDRSIEpvPLKDQLRQVQEELGTITDKL 1854
Cdd:TIGR02168 996 EELKERYDFLTAQK-EDLTEAKETLEEAIEEIDREARE--RFKDTFDQVNENFQRVFPKL 1052
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1515-2142 |
2.76e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 2.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1515 NIQKITHALNDIQNQQFELDLLIERSQEVLRLADANNkktiEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQW 1594
Cdd:TIGR02168 187 NLDRLEDILNELERQLKSLERQAEKAERYKELKAELR----ELELALLVLRLEELREELEELQEELKEAEEELEELTAEL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1595 SLIETKVTAIEekgkLLDTVVRSKQHLYDtiKSLHELVTEAEKLKPMAAEvkalsgpvlaylaafteapahaLEEKLNKL 1674
Cdd:TIGR02168 263 QELEEKLEELR----LEVSELEEEIEELQ--KELYALANEISRLEQQKQI----------------------LRERLANL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1675 QNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLYIFGPDQ----DATEEELDELRWAVEQLLES 1750
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrlEELEEQLETLRSKVAQLELQ 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1751 GKKFSG------STKARYQASQQLVPSDLAQHLTALELCA-EATAQAMEEKQREQKRARTVRSDYLTDLDEVQAWIRQAE 1823
Cdd:TIGR02168 395 IASLNNeierleARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1824 LKVQDrsiepvpLKDQLRQVQEELgtitDKLERLTRNGRTIAENTRDDTEKQLIDSTVHNVTEQLNQVRN-W-------L 1895
Cdd:TIGR02168 475 QALDA-------AERELAQLQARL----DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgYeaaieaaL 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1896 DERKQ--VVADTIDAWQRFLSLYEAvrtwTEEKRQFLVEPLKLSTLVQA--RQRLHEYSTAVKSCKQINKNLSDMGKELE 1971
Cdd:TIGR02168 544 GGRLQavVVENLNAAKKAIAFLKQN----ELGRVTFLPLDSIKGTEIQGndREILKNIEGFLGVAKDLVKFDPKLRKALS 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1972 SI-GQVCSVGDLPE-----KLLEAEEAKVQVEGQLL-----------ERNALLQETSEEWEQCERKMKEVKTWIEKAKQS 2034
Cdd:TIGR02168 620 YLlGGVLVVDDLDNalelaKKLRPGYRIVTLDGDLVrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKA 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2035 LESpqnkkkpLRDQHSIREKMLSDIAiqktKIGISMEKLQVHFRSGIggdSRIGETVDELLAELDNLHANVKEQTTALEG 2114
Cdd:TIGR02168 700 LAE-------LRKELEELEEELEQLR----KELEELSRQISALRKDL---ARLEAEVEQLEERIAQLSKELTELEAEIEE 765
|
650 660
....*....|....*....|....*...
gi 373194212 2115 CLAQIDQYQQEIQQLRQQIMQVEQQLRT 2142
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQ 793
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
2960-3280 |
4.09e-08 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 61.18 E-value: 4.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2960 LKEIEDMDKQKKRDKSREQTkikdttqTVQTEKYKEDIEKKGVKPGEKKK-----QNKSKMEKIRDESEIAMNQANAKEQ 3034
Cdd:NF033838 104 LNVLKEKSEAELTSKTKKEL-------DAAFEQFKKDTLEPGKKVAEATKkveeaEKKAKDQKEEDRRNYPTNTYKTLEL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3035 MKSKNDTKESKEEKNIEKRNAK---DEAKI--SKEKVESRKNESEKRSEIKIDsssemrKIETKEEKAQKDSANLSKKKQ 3109
Cdd:NF033838 177 EIAESDVEVKKAELELVKEEAKeprDEEKIkqAKAKVESKKAEATRLEKIKTD------REKAEEEAKRRADAKLKEAVE 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3110 KGkeqtgtvKDKSNKDSVKStkteneseQMKKAIFIEDKTEIQKEKDIKPVENignldqlQKQEDTKSVKLMKSEKI--- 3186
Cdd:NF033838 251 KN-------VATSEQDKPKR--------RAKRGVLGEPATPDKKENDAKSSDS-------SVGEETLPSPSLKPEKKvae 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3187 SETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQ---KEEKKTEQSKQKKSVEKSEVIDIKLEENEK 3263
Cdd:NF033838 309 AEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELelvKEEAKEPRNEEKIKQAKAKVESKKAEATRL 388
|
330
....*....|....*..
gi 373194212 3264 IKIEIDVKAPKDEKEKK 3280
Cdd:NF033838 389 EKIKTDRKKAEEEAKRK 405
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2798-3556 |
4.61e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.14 E-value: 4.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2798 QEARQTRESSVSKQESNWDITKKRETRKTHQEAPKTKIPEKRARRGSEYSKEKLQKEKIKINMEQQKQVfETKDEIVVED 2877
Cdd:pfam02463 296 EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL-QEKLEQLEEE 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2878 TSKINVKNNEVEIKKEKVEDVQPEKRVDVEKTKKIEAQKQDEKQEIQEEKHDvQQRSRSQEKKRKGKKKKPEKSMDDEID 2957
Cdd:pfam02463 375 LLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEEL 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2958 KALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAMNQANAKEQMKS 3037
Cdd:pfam02463 454 EKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD 533
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3038 KNDTKESKEEKNIEKRNAKDEA-KISKEKVESRKNESEKRSEIKIDSSSEMRKIETKEEKAQKDSANLSKKKQKG--KEQ 3114
Cdd:pfam02463 534 LGVAVENYKVAISTAVIVEVSAtADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLdkATL 613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3115 TGTVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKSEKISETKVESK 3194
Cdd:pfam02463 614 EADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEE 693
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3195 EKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEKIKIEIDVKAPK 3274
Cdd:pfam02463 694 ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKE 773
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3275 DEKEKKITGKEKEKKSESKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKESSTPKKEMKKA 3354
Cdd:pfam02463 774 KELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3355 GEAEkqiktKGGKKSKKEADINQKPATEIIKKEETIIVDKQIIEEKIDEKIIIEESKKEHLKLESVVPNTEQSEMKKHKK 3434
Cdd:pfam02463 854 EELE-----RLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE 928
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3435 SKSPKRGKKEENLKFVEKEKTEKketqgETIKLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQTD 3514
Cdd:pfam02463 929 ILLKYEEEPEELLLEEADEKEKE-----ENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 373194212 3515 KIEIQSAIEKIPEKIIVegsmETFTETVEIAKETEKVKVSDT 3556
Cdd:pfam02463 1004 KKKLIRAIIEETCQRLK----EFLELFVSINKGWNKVFFYLE 1041
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1357-2141 |
4.66e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.23 E-value: 4.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1357 REMEERGNYLESNMKLRQEYAALTEKLRSWVRE-AEIRLESDKDGLDFenilsdleehkiyfssepsirelVSQQIQQAG 1435
Cdd:TIGR02168 196 NELERQLKSLERQAEKAERYKELKAELRELELAlLVLRLEELREELEE-----------------------LQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1436 DKIwpslnTSEQEELSAEQQQHTQLlkntlntaKSQRARLEQGAEtwrDYTQTLERVRAVIARsrftdepvttlagLQFN 1515
Cdd:TIGR02168 253 EEL-----EELTAELQELEEKLEEL--------RLEVSELEEEIE---ELQKELYALANEISR-------------LEQQ 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1516 IQKITHALNDIQNQQFELDLLIERSQEVlRLADANNKKTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWS 1595
Cdd:TIGR02168 304 KQILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1596 LIETKVTAIEEKGKLLD-TVVRSKQHLYDTIKSLHELVTEAEKLkpmaaevkalsgpvlayLAAFTEAPAHALEEKLNKL 1674
Cdd:TIGR02168 383 TLRSKVAQLELQIASLNnEIERLEARLERLEDRRERLQQEIEEL-----------------LKKLEEAELKELQAELEEL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1675 QNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLyifgpdqDATEEELDELRWAVEQLLESGKKF 1754
Cdd:TIGR02168 446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-------ERLQENLEGFSEGVKALLKNQSGL 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1755 SG---------STKARYQAS---------QQLVPSDLAQHLTALELCAEA-------------TAQAMEEKQREQKRART 1803
Cdd:TIGR02168 519 SGilgvlseliSVDEGYEAAieaalggrlQAVVVENLNAAKKAIAFLKQNelgrvtflpldsiKGTEIQGNDREILKNIE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1804 VRSDYLTDLDEVQAwirQAELKVQDRSIEPVPLKD------QLRQVQEELGTITDKLERLTRNG---------------- 1861
Cdd:TIGR02168 599 GFLGVAKDLVKFDP---KLRKALSYLLGGVLVVDDldnaleLAKKLRPGYRIVTLDGDLVRPGGvitggsaktnssiler 675
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1862 -RTIAENTRddtEKQLIDSTVHNVTEQLNQVRNWLDERKQVVADTIDAWQrflslyEAVRTWTEEKRQFLVEPLKLSTLV 1940
Cdd:TIGR02168 676 rREIEELEE---KIEELEEKIAELEKALAELRKELEELEEELEQLRKELE------ELSRQISALRKDLARLEAEVEQLE 746
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1941 QARQRLHEYSTAVKscKQINKNLSDMGKELESIGQVCSV-GDLPEKLLEAEEAKVQVEGQLLERNALLQETSEEWEQCER 2019
Cdd:TIGR02168 747 ERIAQLSKELTELE--AEIEELEERLEEAEEELAEAEAEiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2020 KMKEVKTWIEKAKQSLESPQNKKKPLRDQHSIREKMLSDIAIQKTKIGISMEKLQVHFRSGIGGDSRIGETVDELLAELD 2099
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 373194212 2100 NLHANVKEQTTALEGCLAQIDQYQQEIQQLRQQIMQVEQQLR 2141
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
606-1130 |
5.31e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 60.82 E-value: 5.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 606 DIEEGLNKLEAELTDAIAGKQAAQDLIQKY---RTQVQNMQSWLDTLSKKVDVIEKgNGQTIGQKIASVKEITTEFESQG 682
Cdd:PRK02224 217 ELDEEIERYEEQREQARETRDEADEVLEEHeerREELETLEAEIEDLRETIAETER-EREELAEEVRDLRERLEELEEER 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 683 PGKLNEV-------KTLSDQVMD------------SVSNLDSQQIEEQIKSVERRYADI---GKKLQRKAQVLDmtaQGI 740
Cdd:PRK02224 296 DDLLAEAglddadaEAVEARREEledrdeelrdrlEECRVAAQAHNEEAESLREDADDLeerAEELREEAAELE---SEL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 741 EATRQEIEENRDWIQQKKKQAQ-MSEPVGF---DSKQAEERLLALKAMLKEAEGKqmvIDTLEKRVGNMQNELEsnEQQQ 816
Cdd:PRK02224 373 EEAREAVEDRREEIEELEEEIEeLRERFGDapvDLGNAEDFLEELREERDELRER---EAELEATLRTARERVE--EAEA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 817 LENETKALRGEQSqlctilTEGISSATVAADARRKFEaDLERARSWIKSKSNNLKKlsgylplkasKVEQdIVQHGELET 896
Cdd:PRK02224 448 LLEAGKCPECGQP------VEGSPHVETIEEDRERVE-ELEAELEDLEEEVEEVEE----------RLER-AEDLVEAED 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 897 DIDSFSEK--DLNDILKQGnnllKECSEEDRARLnkilDELNKDYEELKSEAQEKQAALADLlqgrkafESEIDKCqrwi 974
Cdd:PRK02224 510 RIERLEERreDLEELIAER----RETIEEKRERA----EELRERAAELEAEAEEKREAAAEA-------EEEAEEA---- 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 975 neAEVATSSDVRTSSIDILREQLAKYDRLKKEANEYADDIEKLMQQGKSiLPTVTDadklELNEQLQNMKEAHGRVAGII 1054
Cdd:PRK02224 571 --REEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREA-LAELND----ERRERLAEKRERKRELEAEF 643
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 1055 NERAL-ALQKNIDEAEESLARVAEAIQYMTDvqkELHELNKPIGSrvedVEAMLDAYERILNDLKANKAKLSDLQSI 1130
Cdd:PRK02224 644 DEARIeEAREDKERAEEYLEQVEEKLDELRE---ERDDLQAEIGA----VENELEELEELRERREALENRVEALEAL 713
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10226-10440 |
9.41e-08 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 57.07 E-value: 9.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10226 RYKEYEEKAKEINSSFTEIGQAFSTAfhSSPASLTRTKQQLESVHQMQNRLSSMSVDLESLGVMIQQLREDLSPtDIKSL 10305
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSST--DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP-DAEEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10306 NEQRALFRLQHEDLEHQAALLICRLEERCGLYDRWRDrLARLLAWIGETEIRIQDCDSPNEPEET---LKKLEcEIQSDI 10382
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLESVeelLKKHK-ELEEEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 10383 ALKQRELLWIQNTGQDLVEVAEEEESERLQRSLDELNERWDRLVAMGKARASKLMDLM 10440
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
773-1309 |
1.03e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 773 QAEERLLALKAMLKEAEGKQMVIDTLEKRVGNMQNELES--NEQQQLENETKALRGEQSQLCTILTEGISSATVAADARR 850
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEEleAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 851 KFEADLERARSWIKSKSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSfSEKDLNDILKQGNNLLKECSEEDRARLNK 930
Cdd:COG1196 299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE-AEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 931 I--LDELNKDYEELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEVATSS------DVRTSSIDILREQLAKYDR 1002
Cdd:COG1196 378 EeeLEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleeeeeEEEEALEEAAEEEAELEEE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1003 LKKEANEYADDIEKLMQQGKSILPTVTDADKLELNE--QLQNMKEAHGRVAGIINERALALQKNIDEAEESLARVAEAiq 1080
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLllLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA-- 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1081 YMTDVQKELHELNKPIGSRVEDVEAMLDAYeriLNDLKANKAKLSDLQSINVADLHGVLTQQDDLMKAIESQIAKLRQLL 1160
Cdd:COG1196 536 YEAALEAALAAALQNIVVEDDEVAAAAIEY---LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1161 LLRQQFIALITEIT----TFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIAAEGSTVDRNN 1236
Cdd:COG1196 613 ARYYVLGDTLLGRTlvaaRLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 1237 I--TEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANELAEILDWLEDKEKEVKSRPLLERDPISVEAELQK 1309
Cdd:COG1196 693 LelEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
2845-3198 |
1.74e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 59.29 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2845 EYSKEKLQKE------KIK-INM--EQQKQVFETKDEIVVEDTSKINVKNNEVEIKKEKVEDVQPEKRVDVEKTKKIEAQ 2915
Cdd:PTZ00108 998 EYLLGKLERElarlsnKVRfIKHviNGELVITNAKKKDLVKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADDED 1077
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2916 KQDEKQEIQE-----------------EKHDVQQRSRSQEKKRKGKKKKPEKSMDDeIDKALKEIEDMDKQKKRDKSREQ 2978
Cdd:PTZ00108 1078 DEEELGAAVSydyllsmpiwsltkekvEKLNAELEKKEKELEKLKNTTPKDMWLED-LDKFEEALEEQEEVEEKEIAKEQ 1156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2979 TKIKDTTQTV---QTEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIEKRNA 3055
Cdd:PTZ00108 1157 RLKSKTKGKAsklRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3056 KDEAKISKEKVESRKNESEKRSEIKIDSSSEMRKIETKEEKAQKDSA-------NLSKKKQKGKEQTGTVKDKSNKDSVK 3128
Cdd:PTZ00108 1237 KSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYsppppskRPDGESNGGSKPSSPTKKKVKKRLEG 1316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3129 STKTENESEQMKKAIfIEDKTEIQKEKDIKPVEnigNLDQLQKQEDTKSVKLMKSEKISETKVESKEKEP 3198
Cdd:PTZ00108 1317 SLAALKKKKKSEKKT-ARKKKSKTRVKQASASQ---SSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDE 1382
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1268-1477 |
1.76e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 56.30 E-value: 1.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1268 EHKRLANELAEILDWLEDKEKEVKSrPLLERDPISVEAELQKHNELCDAVNEHLDRIRNLKNS----VPHEEGMPGSLKE 1343
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSS-TDYGDDLESVEALLKKHEALEAELAAHEERVEALNELgeqlIEEGHPDAEEIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1344 MLSEAVSLLTSLPREMEERGNYLESNMKLRQEYAALTEkLRSWVREAEIRLESDKDGLDFENILSDLEEHKIyFSSEPSI 1423
Cdd:cd00176 80 RLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALASEDLGKDLESVEELLKKHKE-LEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 373194212 1424 RELVSQQIQQAGDKIWPSLNTSEQEELSAEQQQHTQLLKNTLNTAKSQRARLEQ 1477
Cdd:cd00176 158 HEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
745-957 |
3.62e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 55.14 E-value: 3.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 745 QEIEENRDWIQQKKKQAQMSEPVGfDSKQAEERLLALKAMLKEAEGKQMVIDTLEKRVGNMQNELESNEQQqLENETKAL 824
Cdd:cd00176 7 RDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE-IQERLEEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 825 RGEQSQLCTiLTEGISSATVAADARRKFEADLERARSWIKSKSNNLKklSGYLPLKASKVEQDIVQHGELETDIDSFsEK 904
Cdd:cd00176 85 NQRWEELRE-LAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALA--SEDLGKDLESVEELLKKHKELEEELEAH-EP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 905 DLNDILKQGNNLLKECSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLL 957
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
5888-6590 |
5.61e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 5.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5888 EKELEIEEDKEIQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKSKETKIETISEQITKISIDEKKLSEFEAKEEISS 5967
Cdd:pfam02463 167 LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5968 QIKEEEIikqkrddtDHTKQDITKENEIETFTITSEKLKEKENSIKESTELSQTIAREISDSKIETIEEKKEIKIEQTTE 6047
Cdd:pfam02463 247 RDEQEEI--------ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6048 IEDKSKVSKKEKRKQKrkeksatraTSQEKLKNEKSEAISQEQKGEINIVSKTSDELKTEEISTEIILTNENKEKKDTNE 6127
Cdd:pfam02463 319 SEKEKKKAEKELKKEK---------EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSA 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6128 ISKEIEKLILSEVIPDEIKLVPETMPIPIPKEEIKIIKEKIELSKSIEEQEIISDEIKLVPETLSISISKEEIKPIKEIA 6207
Cdd:pfam02463 390 AKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6208 EFpKPTEEKKVVSDKIKLETIVIPISEDisENSIKEKTELPKPKQNEISDEIKLVPESLSISISKEEIQPIKEIIELSKS 6287
Cdd:pfam02463 470 SE-DLLKETQLVKLQEQLELLLSRQKLE--ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6288 IEEKEEIINKTKDIVE-EKGEIIKPMIDKDKKQEESSFKKSKRKNKQAKKIKHEEAETEIKSADEDLLSSKIEKNIEILS 6366
Cdd:pfam02463 547 TAVIVEVSATADEVEErQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVE 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6367 TGSSTPSPDTPKDIFQIEEKILNVTIPEQKIEVIDILTIDEIKKDEKEIKNTTEQKIIFEEEKTLSKTQEEIEEinlQKI 6446
Cdd:pfam02463 627 GILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLE---IKK 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6447 EEIPSTSPIKKKVMKEDKSKNDDKEIHEIKSLTTEEKIVHQTSEVIEDTIIPFEVEKPIETIESTEVTINGILKEETDEI 6526
Cdd:pfam02463 704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 373194212 6527 EKEIIKIEATEEIYPEIVKENIIQEIDKVPEQFIPIEKLLDEIESPIIIDSIESQLETEEEFEK 6590
Cdd:pfam02463 784 EKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1807-2009 |
8.70e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 53.99 E-value: 8.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1807 DYLTDLDEVQAWIRQAELKVQDRSIEPVP-----LKDQLRQVQEELGTITDKLERLTRNGRTIAENTRDDTEKqlIDSTV 1881
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLesveaLLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE--IQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1882 HNVTEQLNQVRNWLDERKQVVADTIDAWQRFLSLYEaVRTWTEEKRQFL--VEPLKLSTLVQARQRLHE-YSTAVKSCKQ 1958
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALasEDLGKDLESVEELLKKHKeLEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 373194212 1959 INKNLSDMGKELESIGQVCSVGDLPEKLLEAEEAKVQVEGQLLERNALLQE 2009
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
5559-6140 |
1.01e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.07 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5559 EADKIMEVNGTQE--KIAEKSKIETKEQSSVKKNKKSKKGKSDKDQSKHEFKDKEQDKQiDNAQTTEvELKLKDEITKES 5636
Cdd:PTZ00121 1222 DAKKAEAVKKAEEakKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-DELKKAE-EKKKADEAKKAE 1299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5637 EIKDQEEAKENISEIKSKEIQEKSNENIFDNESELLQETKSDKSMQSEKRKKkskerkvEIAPKQVIETFIEENKVLESE 5716
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE-------AEAAADEAEAAEEKAEAAEKK 1372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5717 IQKEILKEQSEAKDIQDIKATTELVQETIYEKPTSSgkrkgkskekkkaitteiAIKEKEVSRPEIKEILKKESDIEEIK 5796
Cdd:PTZ00121 1373 KEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAD------------------ELKKAAAAKKKADEAKKKAEEKKKAD 1434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5797 EIEEIEEKlktiMKSEDEYKSEivQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISLEQIIEISIE 5876
Cdd:PTZ00121 1435 EAKKKAEE----AKKADEAKKK--AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5877 KNKPEIKGKISEK----ELEIEEDK----EIQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKSKETKIETISEQITK 5948
Cdd:PTZ00121 1509 KKKADEAKKAEEAkkadEAKKAEEAkkadEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK 1588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5949 IsiDEKKLSEFEAKEEISSQIKEEEIIK--QKRDDTDHTKQDITKENEIETFTITSEKLKEKENSIKESTELSQTIAREI 6026
Cdd:PTZ00121 1589 A--EEARIEEVMKLYEEEKKMKAEEAKKaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6027 SDSKIETIEEKKEIKIEQTTEIEDKSKVSKKEKRKQKRKEKSATRATSQEKL----KNEKSEAISQEQ-KGEINIVSKTS 6101
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelkKAEEENKIKAEEaKKEAEEDKKKA 1746
|
570 580 590
....*....|....*....|....*....|....*....
gi 373194212 6102 DELKTEEISTEIILTNENKEKKDTNEISKEIEKLILSEV 6140
Cdd:PTZ00121 1747 EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2798-3153 |
1.05e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.69 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2798 QEARQTRESSVSKQEsnwdITKKRETRKTHQEAPKTKIPEKRarRGSEYSKEKlqkEKIKINMEQQKQVFEtkdeivvED 2877
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEE----LKKAEEEKKKVEQLKKKEAEEKK--KAEELKKAE---EENKIKAAEEAKKAE-------ED 1673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2878 TSKINVKNNEVEIKKEKVEDVQPEKrvdvEKTKKIEAQKQDEkqeiQEEKHDVQQRSRSQEKKRKGKKKKPEKSMDDEid 2957
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKKAAEALKKEA----EEAKKAEELKKKE----AEEKKKAEELKKAEEENKIKAEEAKKEAEEDK-- 1743
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2958 kalKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDIEKKGVkpgeKKKQNKSKMEKIRDESEIAMNQANAKEQMKS 3037
Cdd:PTZ00121 1744 ---KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEEL----DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3038 K----NDTKESK----EEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIKIDSSSEMRKIETKEEKAQKdsANLSKKKQ 3109
Cdd:PTZ00121 1817 GnlviNDSKEMEdsaiKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEE--ADEIEKID 1894
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 373194212 3110 KGKEQTGTVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQK 3153
Cdd:PTZ00121 1895 KDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIK 1938
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
3925-4269 |
1.12e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 56.47 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3925 EMMVKKEVNVFEKIESERFKDSREL-VVENEDKSVKEKQETNKTVEELLftvgkgEDVKNAVEELleaeRQAMVVEQKIV 4003
Cdd:PRK05771 4 VRMKKVLIVTLKSYKDEVLEALHELgVVHIEDLKEELSNERLRKLRSLL------TKLSEALDKL----RSYLPKLNPLR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4004 DiEKGETVPVKLE----DSKFKLEEIENKTILNEEKIRDLEKSIEvpvKIETeevnnkttivEEKVIEKGVEVPVDIK-- 4077
Cdd:PRK05771 74 E-EKKKVSVKSLEelikDVEEELEKIEKEIKELEEEISELENEIK---ELEQ----------EIERLEPWGNFDLDLSll 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4078 ---SVTKEIEGKITLPEEKVAEFEKSIEVPIKINDTKLET-----EEIKLEDKVDSEKQ----ERIEIEDFKSIMKGIED 4145
Cdd:PRK05771 140 lgfKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvvvVLKELSDEVEEELKklgfERLELEEEGTPSELIRE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4146 KTDLIEEKlidTGKREDVSIKLKKIENKPTQDEEKIKEVPINIKDFESIIEKI-NSETIL-----VEEKDLKekieiplE 4219
Cdd:PRK05771 220 IKEELEEI---EKERESLLEELKELAKKYLEELLALYEYLEIELERAEALSKFlKTDKTFaiegwVPEDRVK-------K 289
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 373194212 4220 IKSITEEVEDKTALFEEkvVESEKSFKEVPVKIDYSKSqeeIKVEEKIVE 4269
Cdd:PRK05771 290 LKELIDKATGGSAYVEF--VEPDEEEEEVPTKLKNPKF---IKPFESLTE 334
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1423-1907 |
2.03e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 2.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1423 IRELVSQQIQQAGDKIW------PSLNTSEQEELSAE----QQQHTQL--LKNTLNTAKSQRARLEQGAETWRDYTQTLE 1490
Cdd:COG4717 43 IRAMLLERLEKEADELFkpqgrkPELNLKELKELEEElkeaEEKEEEYaeLQEELEELEEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1491 RVRAVIARSRFTDEPVTTLAGLQFNIQKITHALNDIQNQQFELDLL---IERSQEVLRLADANNKKTIEAQISEISAEWK 1567
Cdd:COG4717 123 KLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELeaeLAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1568 ELVSGLEGRRDALEALSKHWEDLEAQWSLIETKVTAIEEKGKLLDTVVRSKqhLYDTIKSLHELVTEAEKLKPMAAEVKA 1647
Cdd:COG4717 203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLL--IAAALLALLGLGGSLLSLILTIAGVLF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1648 LSGPVLAYLAAFTEAPAHALEEKLNKLQNSV-------ESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERA 1720
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAEELQALPaleeleeEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1721 SNLyifgpDQDATEEELDEL--------RWAVEQLLESGKKFSGSTKARYQASQQLVPSDLAQHLTALELCAEATAQAME 1792
Cdd:COG4717 361 EEL-----QLEELEQEIAALlaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1793 EKQREQKRARTVRSDYLTDLDEVQAWIRQAElkvQDRSIEpvplkDQLRQVQEELGTITDKLERLTRN--GRTIAENTRD 1870
Cdd:COG4717 436 ELEEELEELEEELEELREELAELEAELEQLE---EDGELA-----ELLQELEELKAELRELAEEWAALklALELLEEARE 507
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 373194212 1871 DTEKQLIDSTVHNVTEQLNQV------RNWLDERKQVVADTID 1907
Cdd:COG4717 508 EYREERLPPVLERASEYFSRLtdgryrLIRIDEDLSLKVDTED 550
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
705-1077 |
2.57e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.46 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 705 SQQIEEQIKSVERRYADIGKKLQRKAQVLDMTAQGIEATRQEIEENRDWIQQKKKQAQMS----EPVGFDSKQAEERLLA 780
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLkerlEELEEDLSSLEQEIEN 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 781 LKAMLKEAEGKqmvIDTLEKRVGNMQNELESNEQQQLENETKALRGEQSQLCTILTEgISSATVAADARrkfeadlerar 860
Cdd:TIGR02169 756 VKSELKELEAR---IEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSR-IEARLREIEQK----------- 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 861 swiksksnnLKKLSGYLPLKASKVEQDIVQHGELETDIDSFSEKdlndilkqgnnllkecseedrarlnkiLDELNKDYE 940
Cdd:TIGR02169 821 ---------LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE---------------------------IENLNGKKE 864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 941 ELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEVATssDVRTSSIDILREQLAKYDRLKKEANEYADDIEKLMQQ 1020
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI--EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 1021 GKSILPTVTDADKLELNEQlqnMKEAHGRVAGIINERAlalqknIDEAEESLARVAE 1077
Cdd:TIGR02169 943 DEEIPEEELSLEDVQAELQ---RVEEEIRALEPVNMLA------IQEYEEVLKRLDE 990
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1619-1867 |
2.78e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1619 QHLYDTIKSLHELVTEAEKlkpmaaEVKALSgPVLAYLAAFTEApahalEEKLNKLQNSVESL-IDTLQTKSKKADEDLE 1697
Cdd:COG4913 231 VEHFDDLERAHEALEDARE------QIELLE-PIRELAERYAAA-----RERLAELEYLRAALrLWFAQRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1698 tfeSTEREIDQLRKRLNEARERasnlyifgpdQDATEEELDELRwavEQLLESG--------KKFSGSTKARYQASQQLv 1769
Cdd:COG4913 299 ---ELRAELARLEAELERLEAR----------LDALREELDELE---AQIRGNGgdrleqleREIERLERELEERERRR- 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1770 pSDLAQHLTALELCAEATAQAMEEKQREQKRArtvrsdyLTDLDEVQAWIRQAelkvQDRsiepvpLKDQLRQVQEELGT 1849
Cdd:COG4913 362 -ARLEALLAALGLPLPASAEEFAALRAEAAAL-------LEALEEELEALEEA----LAE------AEAALRDLRRELRE 423
|
250
....*....|....*...
gi 373194212 1850 ITDKLERLTRNGRTIAEN 1867
Cdd:COG4913 424 LEAEIASLERRKSNIPAR 441
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10446-10662 |
4.01e-06 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 52.06 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10446 LEKRINELRSWLASVESQLSETFVVEAIEQscIDKKLDDHEHLQKTIEAESGNIGEVLNLCEILLNDCDAWKTSfnnaIK 10525
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYGDDLES--VEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE----IQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10526 SGMEGLERRWTTTCVKSAERKGNIILAWKILQELEKIRlEQEGWLAETDKALAELENNLDEvskDESKKAIEKARSISED 10605
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLGKDL---ESVEELLKKHKELEEE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 10606 VEAHEPVIKIIEQNFGRLARTGlEPDNLKSLISETRRLIDKWQTFKPRANAVLLALQ 10662
Cdd:cd00176 155 LEAHEPRLKSLNELAEELLEEG-HPDADEEIEEKLEELNERWEELLELAEERQKKLE 210
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
2953-3130 |
6.51e-06 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 53.47 E-value: 6.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2953 DDEIDKALKEiedmDKQKKRDKSREQTKIKDTTQTVQTEK---YKEDIEKKGVKPGEKKKQNKSK---MEKIRDESEIAM 3026
Cdd:pfam05262 179 DKKVVEALRE----DNEKGVNFRRDMTDLKERESQEDAKRaqqLKEELDKKQIDADKAQQKADFAqdnADKQRDEVRQKQ 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3027 NQANAKEQMKSKNDTKESKEEKNIEKRNA-KDEAKISKEKVESRKNESEKRSEIKIDSSSEMRKIETKEEKAQKDSANLS 3105
Cdd:pfam05262 255 QEAKNLPKPADTSSPKEDKQVAENQKREIeKAQIEIKKNDEEALKAKDHKAFDLKQESKASEKEAEDKELEAQKKREPVA 334
|
170 180
....*....|....*....|....*
gi 373194212 3106 KKKQKGKEQTGTVKDKSNKDSVKST 3130
Cdd:pfam05262 335 EDLQKTKPQVEAQPTSLNEDAIDSS 359
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
2968-3346 |
6.66e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 54.28 E-value: 6.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2968 KQKKRDKSREQTKIKDTTQTVQTE-----KYKEDIEKKGVKPGEK--KKQNKSKMEKIRDESEIAMNQANAKEQmksKND 3040
Cdd:PTZ00108 1002 GKLERELARLSNKVRFIKHVINGElvitnAKKKDLVKELKKLGYVrfKDIIKKKSEKITAEEEEGAEEDDEADD---EDD 1078
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3041 TKESKEEKNIEKRNAKDEAKISKEKVESRKNE-SEKRSEIKI---DSSSEM---------RKIETKEEKAQKDSANLSKK 3107
Cdd:PTZ00108 1079 EEELGAAVSYDYLLSMPIWSLTKEKVEKLNAElEKKEKELEKlknTTPKDMwledldkfeEALEEQEEVEEKEIAKEQRL 1158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3108 KQKGKEQTGTVKDKSNKDSVKSTK---TENESEQMKKAIFIEDKTEIQKEKDIKPVENIGNLDQLQKQEDTKSVKLMKSE 3184
Cdd:PTZ00108 1159 KSKTKGKASKLRKPKLKKKEKKKKkssADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKS 1238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3185 KISETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQqkeEKKTEQSKQKKSVEKSEVIDIKLEENEKI 3264
Cdd:PTZ00108 1239 SVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPP---PPSKRPDGESNGGSKPSSPTKKKVKKRLE 1315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3265 KIEIDVKAPKDEKEKkitgkekekkseSKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKES 3344
Cdd:PTZ00108 1316 GSLAALKKKKKSEKK------------TARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDED 1383
|
..
gi 373194212 3345 ST 3346
Cdd:PTZ00108 1384 DE 1385
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
740-1089 |
6.87e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 6.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 740 IEATRQEIEENRDWIQQKKKQAQMSEpvgfDSKQAEERLLALKAMLKEAEGKQMV--IDTLEKRVGNMQNELESNEQ--- 814
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLkeKEALERQKEAIERQLASLEEele 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 815 ------QQLENETKALRGEQSQLCTILTEGISSATVAADAR-RKFEADLERARSWIKSKSNNLKKLsgylplkASKVEQD 887
Cdd:TIGR02169 255 klteeiSELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDA-------EERLAKL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 888 IVQHGELETDIDSFSEKdlndilkqgnnllKECSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLLQGRKAFESEI 967
Cdd:TIGR02169 328 EAEIDKLLAEIEELERE-------------IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 968 DKCQRWINEAEVATS-----SDVRTSSIDILREQLA----KYDRLKKEANEYADDIEKLMQQGKSILptvtdADKLELNE 1038
Cdd:TIGR02169 395 EKLKREINELKRELDrlqeeLQRLSEELADLNAAIAgieaKINELEEEKEDKALEIKKQEWKLEQLA-----ADLSKYEQ 469
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 373194212 1039 QLQNMKEAHGRVagiiNERALALQKNIDEAEESLARVAEAIQYMTDVQKEL 1089
Cdd:TIGR02169 470 ELYDLKEEYDRV----EKELSKLQRELAEAEAQARASEERVRGGRAVEEVL 516
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
10088-10336 |
8.46e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 8.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10088 EQFNILTNQHNEtLAKIMERHAAVRDRLAAWDRYKLDQSKLlywlKEIERERSQLRFRFIQiQRLDEILQRIESLLEKIP 10167
Cdd:COG4913 232 EHFDDLERAHEA-LEDAREQIELLEPIRELAERYAAARERL----AELEYLRAALRLWFAQ-RRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10168 EGEAQLESLQRQQETLLVKCDEAlavtiHRDHAAS-VQRINNLSSSLEMWRDHIPRIQKRYKEYEEKAKEINSSFTEIGQ 10246
Cdd:COG4913 306 RLEAELERLEARLDALREELDEL-----EAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10247 AFSTAFHSSPASLTRTKQQLESVHQmqnrlssmsvDLESLGVMIQQLREDLsptdiKSLNEQRALFRLQHEDLEHQAALL 10326
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALEE----------ALAEAEAALRDLRREL-----RELEAEIASLERRKSNIPARLLAL 445
|
250
....*....|
gi 373194212 10327 ICRLEERCGL 10336
Cdd:COG4913 446 RDALAEALGL 455
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
96-305 |
1.27e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 50.52 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 96 EFLKAKKEMEDWLRIARGSVQDCMGVGDAEWAKDKLETIKIVATRITEGQHLLSTLQtAFTKAIDTAVPEQQDQLRSDMA 175
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALN-ELGEQLIEEGHPDAEEIQERLE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 176 GLLSSWEQLSIDLNTVQAQLKSLLHRWDDHSEAHgKLKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKT 255
Cdd:cd00176 83 ELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALAS-EDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 256 ELDHLMDEASELSKLAKKNTPL---ERTKELLKRWENLSENVDERKRLIENEM 305
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEeieEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1306-2145 |
1.72e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.92 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1306 ELQKHNELCDAVNE--HLDRIrnlKNSVPHEEGMPGSLKEMLSEAVslltslpremEERGNYLESNMKLRQEYAALTEKL 1383
Cdd:pfam12128 164 SLARQFALCDSESPlrHIDKI---AKAMHSKEGKFRDVKSMIVAIL----------EDDGVVPPKSRLNRQQVEHWIRDI 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1384 RSWVREAEIRLESDKDGLDFENILSDLEE----HKIYFSSEPSIRELvsQQIQQAGDKiwpSLNtSEQEELSAEQQQHTQ 1459
Cdd:pfam12128 231 QAIAGIMKIRPEFTKLQQEFNTLESAELRlshlHFGYKSDETLIASR--QEERQETSA---ELN-QLLRTLDDQWKEKRD 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1460 LLKNTLNTAKsqrarleqgaETWRDYTQTLERVRAviARSRFTDEPVTTLAGLQFNIQKIThalNDIQNQQFELDLLIER 1539
Cdd:pfam12128 305 ELNGELSAAD----------AAVAKDRSELEALED--QHGAFLDADIETAAADQEQLPSWQ---SELENLEERLKALTGK 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1540 SQEVLRLADANNKKTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWslietkvtaieekgklldtvvrsKQ 1619
Cdd:pfam12128 370 HQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESEL-----------------------RE 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1620 HLYDTIKSLHElvtEAEKLKPMAAEVKALsgpvlayLAAFTEAPahalEEKLNKLQNsvESLIDTLQTKSKKADEDLETF 1699
Cdd:pfam12128 427 QLEAGKLEFNE---EEYRLKSRLGELKLR-------LNQATATP----ELLLQLENF--DERIERAREEQEAANAEVERL 490
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1700 ESTEREIDQLRKRLNEARERASnlyifgpdqdateEELDELRWAVEQLLESGKKFSGS--------------TKARYQAS 1765
Cdd:pfam12128 491 QSELRQARKRRDQASEALRQAS-------------RRLEERQSALDELELQLFPQAGTllhflrkeapdweqSIGKVISP 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1766 QQLVPSDLAQHLTALELCAEATAQAMEEKQReqkraRTVRSDYLTDLDEVQAWIRQAELKVQDRSiepvplkDQLRQVQE 1845
Cdd:pfam12128 558 ELLHRTDLDPEVWDGSVGGELNLYGVKLDLK-----RIDVPEWAASEEELRERLDKAEEALQSAR-------EKQAAAEE 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1846 ELGTITDKLERLTRN---GRTIAENTRDD---------TEKQLIDSTVHNVTEQLNQVRNWLDERKQVVADTIDAW-QRF 1912
Cdd:pfam12128 626 QLVQANGELEKASREetfARTALKNARLDlrrlfdekqSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWlEEQ 705
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1913 LSLYEAVRTWTEEKRQFLVEPL--KLSTLVQArqRLHEYSTAVKSCKQINKnlsDMGKELESIGqvcsvgdlpeklleae 1990
Cdd:pfam12128 706 KEQKREARTEKQAYWQVVEGALdaQLALLKAA--IAARRSGAKAELKALET---WYKRDLASLG---------------- 764
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1991 eakvqVEGQ-LLERNALLQETSEEWEQCERKMKEVKTWiEKAKQSLESPQNKKkpLRDQHSIREKMLSDIAIQKTKIGIS 2069
Cdd:pfam12128 765 -----VDPDvIAKLKREIRTLERKIERIAVRRQEVLRY-FDWYQETWLQRRPR--LATQLSNIERAISELQQQLARLIAD 836
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2070 MEKLQVHFRSGIGGDSRIGETVDELLAELD---------NLHANVKEQTTALEGCLAQIDQYQQEIQQLRQQIMQVEQQL 2140
Cdd:pfam12128 837 TKLRRAKLEMERKASEKQQVRLSENLRGLRcemsklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHF 916
|
....*
gi 373194212 2141 RTVLS 2145
Cdd:pfam12128 917 KNVIA 921
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3873-4659 |
2.51e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.28 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3873 RRKDRSGTPLSAKSVENAKDEREVDDLKE-GQGVDAKISQDTLGENEGKAEKGEMMVKKEVNVFEKIESERFKDSRELVV 3951
Cdd:pfam02463 237 ERIDLLQELLRDEQEEIESSKQEIEKEEEkLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3952 ENEDKSVKEKQETNKTVE--------ELLFTVGKGEDVKNAVEELLEAERQAMVVEQKIVDIEKGETVPVKLEDS-KFKL 4022
Cdd:pfam02463 317 KESEKEKKKAEKELKKEKeeieelekELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKlKEEE 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4023 EEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKV--IEKGVEVPVDIKSVTKEIEGKITLPEEKVAEFEKS 4100
Cdd:pfam02463 397 LELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIelKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4101 IEVPIKINDTKLETEEIKLEDKVDSEKQERIEIEDFKSIMKGIEDKTDLIEEKLIDTGKREDVSIKLKKIENKPTQDEEK 4180
Cdd:pfam02463 477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSAT 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4181 IKEVPINIKDFESIIEKINSETILVEEKDLKEKIEIPLEIKSIteEVEDKTALFEEKVVESEKSFKEVPVKIDYSKSQEE 4260
Cdd:pfam02463 557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI--DPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4261 IKVEEKIVEKQETivnkDFKSKMENIEDKTILEENIIESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYYFTD 4340
Cdd:pfam02463 635 TKLKESAKAKESG----LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE 710
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4341 LVKpywfnyrpyIKAEIDFYRHFKIVKILEENVPAPVLPRSDSIERIVQESIMKNSKEEEKKIESAEQSETEYTNASQEI 4420
Cdd:pfam02463 711 ELK---------KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4421 IKEKSKETENKTKDTKESETE-----YKHVLQESIEEKSKKIEKKTEDIEESEAEYRKYALIGETFKYPISTFYKLESEW 4495
Cdd:pfam02463 782 KTEKLKVEEEKEEKLKAQEEElraleEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4496 VKSKLIQEKEVTLIPVEESESTNPEINKEIIQIYEEEKLPIELKELEEvipTSVEESKLTDVEVKSPIKSEELEVKNEKV 4575
Cdd:pfam02463 862 EITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL---NLLEEKENEIEERIKEEAEILLKYEEEPE 938
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4576 TLSSGEESKPIEVEIKKEIIEIYEGEKPTLKLEEDKKIINIEKDTMKVIEEVTTEIKSTDRILDQTAALIEDLTKELDMI 4655
Cdd:pfam02463 939 ELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
|
....
gi 373194212 4656 KKEE 4659
Cdd:pfam02463 1019 LKEF 1022
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
3982-4328 |
2.61e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 51.85 E-value: 2.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3982 KNAVEELLEAERQAMVVEqkIVDIEKgetvpvklEDSKFKLEEIENKTILNEEKIRDLEKSIEVpVKIETEEVNNKTTIV 4061
Cdd:PRK05771 15 KSYKDEVLEALHELGVVH--IEDLKE--------ELSNERLRKLRSLLTKLSEALDKLRSYLPK-LNPLREEKKKVSVKS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4062 EEKVIEKGVEVPVDIKSVTKEIEGKITLPEEKVAEFEKSIEVPIKINDtkLETEEIKLEDKvdsekqERIEI------ED 4135
Cdd:PRK05771 84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN--FDLDLSLLLGF------KYVSVfvgtvpED 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4136 FKSIMKGIEDKTDLIEEK----------LIDTGKREDVSIKLKKI--ENKPTQDEEKIKEVpinIKDFESIIEKINSETi 4203
Cdd:PRK05771 156 KLEELKLESDVENVEYIStdkgyvyvvvVVLKELSDEVEEELKKLgfERLELEEEGTPSEL---IREIKEELEEIEKER- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4204 lveeKDLKEkieiplEIKSITEEVEDkTALFEEKVVESEKSFKEVPVKIdysKSQEEIKVEEKIVEKQEtivNKDFKSKM 4283
Cdd:PRK05771 232 ----ESLLE------ELKELAKKYLE-ELLALYEYLEIELERAEALSKF---LKTDKTFAIEGWVPEDR---VKKLKELI 294
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 373194212 4284 ENIEDKtileeniieseksiEVLVEVKDSKKIEEEVPVEIKDSKS 4328
Cdd:PRK05771 295 DKATGG--------------SAYVEFVEPDEEEEEVPTKLKNPKF 325
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
2853-3255 |
4.22e-05 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 51.59 E-value: 4.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2853 KEKIKINMEQQKQVFETKD---EIVVEDTSKI-NVKnneveiKKEKVEDVQPEKRVDVEKTKKIEAQKQDEKQEIQEEKH 2928
Cdd:PTZ00108 997 KEYLLGKLERELARLSNKVrfiKHVINGELVItNAK------KKDLVKELKKLGYVRFKDIIKKKSEKITAEEEEGAEED 1070
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2929 DVQQRSRSQEKKRKGKKKKPEKSM---DDEIDKALKEIEDMDKQKKRDKSREQTKIKD--TTQTVQTEKYKEDIEKKGVK 3003
Cdd:PTZ00108 1071 DEADDEDDEEELGAAVSYDYLLSMpiwSLTKEKVEKLNAELEKKEKELEKLKNTTPKDmwLEDLDKFEEALEEQEEVEEK 1150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3004 pgEKKKQNKSKMEKIRDESEIAmNQANAKEQMKSKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIkidS 3083
Cdd:PTZ00108 1151 --EIAKEQRLKSKTKGKASKLR-KPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGS---D 1224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3084 SSEMRKIETKEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQKEKDIKPveni 3163
Cdd:PTZ00108 1225 QEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGS---- 1300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3164 gnldqlqKQEDTKSVKLMKSEKISETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQ--SQQKEEKKTEQ 3241
Cdd:PTZ00108 1301 -------KPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKsdSSSEDDDDSEV 1373
|
410
....*....|....
gi 373194212 3242 SKQKKSVEKSEVID 3255
Cdd:PTZ00108 1374 DDSEDEDDEDDEDD 1387
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
513-1142 |
4.75e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 4.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 513 RNKLEELIDQAQGHLMNVTKALNELEEQTRQKNVLRAwINQQRALCAEWKSRPAKLRSEAALAELQAMNDLLGNVGERRT 592
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 593 HALTELSLHEDDQDI-EEGLNKLEAELTDAIAGKQAAQ-DLIQKYRTQVQNMQSWLDTLSKKVDVIEKgNGQTIGQKIAS 670
Cdd:COG4913 299 ELRAELARLEAELERlEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEA-LLAALGLPLPA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 671 VKEITTEFESQGPGKLNEVKTLSDQVMDSVSNLDSQ---------QIEEQIKSVERRYADIGKKLQrkaQVLDMTAQGIE 741
Cdd:COG4913 378 SAEEFAALRAEAAALLEALEEELEALEEALAEAEAAlrdlrrelrELEAEIASLERRKSNIPARLL---ALRDALAEALG 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 742 ATRQEI----------EENRDW---------------IQQKKKQAQMSEPVgfDSKQAEERL--LALKAMLKEAEGKQMV 794
Cdd:COG4913 455 LDEAELpfvgelievrPEEERWrgaiervlggfaltlLVPPEHYAAALRWV--NRLHLRGRLvyERVRTGLPDPERPRLD 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 795 IDTLEKRV--------GNMQNELESNE-------QQQLENETKALrgeqsqlcTIltEGISSatvaaDARRKFEADLERA 859
Cdd:COG4913 533 PDSLAGKLdfkphpfrAWLEAELGRRFdyvcvdsPEELRRHPRAI--------TR--AGQVK-----GNGTRHEKDDRRR 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 860 --RSWIKSKSNnlkklsgylplkASKVEQDIVQHGELETDIDsfsekDLNDILKQGNNLLKECseEDRARLNKILDELN- 936
Cdd:COG4913 598 irSRYVLGFDN------------RAKLAALEAELAELEEELA-----EAEERLEALEAELDAL--QERREALQRLAEYSw 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 937 --KDYEELKSEAQEKQAALADLLQGrkafESEIDKCQRWINEAEvatssdvrtSSIDILREQLAKYDRLKKEANEYADDI 1014
Cdd:COG4913 659 deIDVASAEREIAELEAELERLDAS----SDDLAALEEQLEELE---------AELEELEEELDELKGEIGRLEKELEQA 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1015 EKLMQQGKSILPTVTDADKLELNEQLQNMKEAHGrVAGIINERALALQKNIDEAEESLARVAEAI-QYMTDVQKELHELN 1093
Cdd:COG4913 726 EEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAET 804
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 1094 KPIGSRVEDveamLDAYERILNDLKAN-----KAKLSDL---QSIN-VADLHGVLTQQ 1142
Cdd:COG4913 805 ADLDADLES----LPEYLALLDRLEEDglpeyEERFKELlneNSIEfVADLLSKLRRA 858
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1652-1866 |
4.99e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 4.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1652 VLAYLAAFTEAPAHALEEKLNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERAS----NLYIFG 1727
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAaleaELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1728 PDQDATEEELDELRWAVEQLLESGKKFSGSTKARYQASQQlVPSDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSD 1807
Cdd:COG4942 90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 373194212 1808 YLTDLDEVQAWIRQAELKVQDRSIEPVPLKDQLRQVQEELGTITDKLERLTRNGRTIAE 1866
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
5-824 |
5.06e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 5.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5 IDHFQKKVNDEQSKENKTPEDLVRCKSLVEEAIQQKPVLE----------DLNDKCEAL-LELSACSW--ARDKTIQLQS 71
Cdd:TIGR02168 167 ISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLErqaekaerykELKAELRELeLALLVLRLeeLREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 72 AYTSLLTDMQGLVSRVEKNLSDHTEFLKAKKEMEDWLRIARGSVQDCMG-----VGDAEWAKDKLETIKIVATRI-TEGQ 145
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANeisrlEQQKQILRERLANLERQLEELeAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 146 HLLSTLQTAftKAIDTAVPEQQDQLRSDMagllsswEQLSIDLNTVQAQLKSLLHRWDDHSEAHGKLKRWLEEMENSMQD 225
Cdd:TIGR02168 327 ELESKLDEL--AEELAELEEKLEELKEEL-------ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 226 LpdtKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEA--SELS-KLAKKNTPLERTKELLKRWENLSENVDERKRLIE 302
Cdd:TIGR02168 398 L---NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAelKELQaELEELEEELEELQEELERLEEALEELREELEEAE 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 303 NEMQEYNAYHAALQeTEKWLLQISFQLMAHNSLYITNKEQTVSQIQQHENLLVEI----ENYTSVLnDLKLKGNGQitrY 378
Cdd:TIGR02168 475 QALDAAERELAQLQ-ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdEGYEAAI-EAALGGRLQ---A 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 379 VAVNSE--IKTIIETQLQNVQESYNSLLNTAL---QIKKRLAESLIKFQEYENTLESIMKNLDAYEPEIAQEME--APMD 451
Cdd:TIGR02168 550 VVVENLnaAKKAIAFLKQNELGRVTFLPLDSIkgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGgvLVVD 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 452 TLDAA--KQRFENARMLHNKLQGEktrlaLAVEACEAAVACVSRPGSPLdappvqipAREVEVRNkLEELIDQAQGHLMN 529
Cdd:TIGR02168 630 DLDNAleLAKKLRPGYRIVTLDGD-----LVRPGGVITGGSAKTNSSIL--------ERRREIEE-LEEKIEELEEKIAE 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 530 VTKALNELEEQTRQKN----VLRAWINQQRALCAEWKSRPAKLRSEAALAELQAmndllgnvgERRTHALTELSlhEDDQ 605
Cdd:TIGR02168 696 LEKALAELRKELEELEeeleQLRKELEELSRQISALRKDLARLEAEVEQLEERI---------AQLSKELTELE--AEIE 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 606 DIEEGLNKLEAELTDAIAGKQAAQDLIQKYRTQVQNMQSWLDTLSK-----KVDVIEKGNGQTIGQKIASVKEITTEFES 680
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAeltllNEEAANLRERLESLERRIAATERRLEDLE 844
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 681 QGPGKLNE-VKTLSDQVMDSVSNLDSQQIEEQIKSVERRYADIGKKLQRKA-QVLDMTAQGIEATRQEIEENRDWIQQKK 758
Cdd:TIGR02168 845 EQIEELSEdIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSElEELSEELRELESKRSELRRELEELREKL 924
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 759 KQAQMSEpvgfdsKQAEERLLALKAMLkeAEGKQMVIDTLEKRVGNMQNELESNEQQ--QLENETKAL 824
Cdd:TIGR02168 925 AQLELRL------EGLEVRIDNLQERL--SEEYSLTLEEAEALENKIEDDEEEARRRlkRLENKIKEL 984
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
840-1105 |
5.17e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 840 SSATVAADARRKFEADLERARSWIKSKSNNLKKLSGylplKASKVEQDIvqhgeletdidsfseKDLNDILKQGNNLLKE 919
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQL---------------AALERRIAALARRIRA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 920 cSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLLqgRKAFESEIdkcqrwINEAEVATSSDVRTSSIDILR--EQL 997
Cdd:COG4942 74 -LEQELAALEAELAELEKEIAELRAELEAQKEELAELL--RALYRLGR------QPPLALLLSPEDFLDAVRRLQylKYL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 998 AKYDRlkKEANEYADDIEKLMQQGKSIlptvtDADKLELNEQLQNMKEAHGRVAGIINERALALQKNIDEAEESLARVAE 1077
Cdd:COG4942 145 APARR--EQAEELRADLAELAALRAEL-----EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
|
250 260
....*....|....*....|....*...
gi 373194212 1078 AIQYMTDVQKELHELNKPIGSRVEDVEA 1105
Cdd:COG4942 218 LQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
3884-4282 |
5.96e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 5.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3884 AKSVENAKDEREVDDLKEGQGVDAKISQDTlGENEGKAE--KGEMMVKKEVNVFEKIESERFKDSRELVVENEDKSVKEK 3961
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKA-EEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3962 QETNKTVEEllftvgkgedvKNAVEELLEAERqamvveqkivDIEKGETVPVKLEDSKFKLEEIENKTILNEEKIRDLEK 4041
Cdd:PTZ00121 1665 EEAKKAEED-----------KKKAEEAKKAEE----------DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4042 SIEVPvKIETEEVNNKttivEEKVIEKGVEVPVDiKSVTKEIEGKITLPEEKVAEFEKSIEVPIKindtkletEEIKLED 4121
Cdd:PTZ00121 1724 AEEEN-KIKAEEAKKE----AEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIE--------EELDEED 1789
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4122 KVDSEKQERiEIEDFKSIMKGIEDKTDLIEEKLIDTGKREDVSIKLKKIENKPTQDEEKIKEVPINIKDFESiIEKINSE 4201
Cdd:PTZ00121 1790 EKRRMEVDK-KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNEN-GEDGNKE 1867
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4202 TILVEEKDLKEK-IEIPLEIKSITEEVEDKTALFEEKVVESEKSFKEVPVKID---YSKSQEEIKVEEKIVEKQETIVNK 4277
Cdd:PTZ00121 1868 ADFNKEKDLKEDdEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDkdeYIKRDAEETREEIIKISKKDMCIN 1947
|
....*
gi 373194212 4278 DFKSK 4282
Cdd:PTZ00121 1948 DFSSK 1952
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
128-969 |
6.35e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 6.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 128 KDKLETIKI--VATRITEGQHLLSTLQTAFTKAIdtavpEQQDQLRSDMAGLLSSWEQLSIDLNTVQAQLKSLLHRWDDH 205
Cdd:TIGR02168 219 KAELRELELalLVLRLEELREELEELQEELKEAE-----EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 206 SEAHGKLKRWLEEMENSMQDLPDTkgefgdmktmLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNtpLERTKELLK 285
Cdd:TIGR02168 294 ANEISRLEQQKQILRERLANLERQ----------LEELEAQLEELESKLDELAEELAELEEKLEELKEE--LESLEAELE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 286 RWENLSENVDERKRLIENEMQEYNAYHAALQETEKwllqisfQLMAHnslyITNKEQTVSQIQQH-ENLLVEIENYTSVL 364
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIA-------SLNNE----IERLEARLERLEDRrERLQQEIEELLKKL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 365 NDLKLKgngqitryvAVNSEIKTiIETQLQNVQESYNSLLNTALQIKKRLAESLIKFQEYENTLESIMKNLDAYEpeiaQ 444
Cdd:TIGR02168 431 EEAELK---------ELQAELEE-LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE----R 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 445 EMEAPMDTLDAAKQRFENARMLHNKLQ--------GEKTRLALAVEAceaavacvsrpGSPLDAppvqipareVEVRNkl 516
Cdd:TIGR02168 497 LQENLEGFSEGVKALLKNQSGLSGILGvlselisvDEGYEAAIEAAL-----------GGRLQA---------VVVEN-- 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 517 EELIDQAQGHLMNVTK------ALNELEEQTRQKNVL--RAWINQQRALCAEWKSRPAKLRSeaalaelqAMNDLLGNV- 587
Cdd:TIGR02168 555 LNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDReiLKNIEGFLGVAKDLVKFDPKLRK--------ALSYLLGGVl 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 588 -------------------------GER--------RTHALTELSLHEDDQDIEEglnkLEAELTDAIAGKQAAQDLIQK 634
Cdd:TIGR02168 627 vvddldnalelakklrpgyrivtldGDLvrpggvitGGSAKTNSSILERRREIEE----LEEKIEELEEKIAELEKALAE 702
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 635 YRTQVQNMQSWLDTLSKKvdviekgnGQTIGQKIASVKEITTEFESQgpgklnevktlsdqvmdsvsnldSQQIEEQIKS 714
Cdd:TIGR02168 703 LRKELEELEEELEQLRKE--------LEELSRQISALRKDLARLEAE-----------------------VEQLEERIAQ 751
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 715 VERRYADIGKKLQRKAQVLDMTAQGIEATRQEIEENRDWIQQKKKQAQMSEPvGFDSKQAEERLL---------ALKAML 785
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE-ALDELRAELTLLneeaanlreRLESLE 830
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 786 KEAEGKQMVIDTLEKRVGNMQNELESNEqQQLENETKALRGEQSQLcTILTEGISSATVAADARRKfeaDLERARSWIKS 865
Cdd:TIGR02168 831 RRIAATERRLEDLEEQIEELSEDIESLA-AEIEELEELIEELESEL-EALLNERASLEEALALLRS---ELEELSEELRE 905
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 866 KSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSFSEK------DLNDILKQGNNLLKECSEEDRARLNKILDELNK-- 937
Cdd:TIGR02168 906 LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKElg 985
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 373194212 938 --------DYEELKSEAQEKQAALADLLQGRKAFESEIDK 969
Cdd:TIGR02168 986 pvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
8257-8448 |
7.01e-05 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 50.81 E-value: 7.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8257 QTVEEEAPKIEEISTQTMESPVKKMEEyavqtspiedikEIVPIETEEIQVQTVATEVASIEAQTSPTAPfmeIETQTAE 8336
Cdd:PRK10811 854 QVEEQREAEEVQVQPVVAEVPVAAAVE------------PVVSAPVVEAVAEVVEEPVVVAEPQPEEVVV---VETTHPE 918
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8337 KVVVAVEQQttPPPIEEKILTgiAVQTVTPEVPKTTETEAQTSKPTTPEITTLDFNVQADLIEQPVVDVVETQTTPEESP 8416
Cdd:PRK10811 919 VIAAPVTEQ--PQVITESDVA--VAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETV 994
|
170 180 190
....*....|....*....|....*....|..
gi 373194212 8417 RQAETHETESQtiQPEPTQEIMIQTCPVTFAP 8448
Cdd:PRK10811 995 TAVEPEVAPAQ--VPEATVEHNHATAPMTRAP 1024
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
730-984 |
7.91e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 7.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 730 AQVLDMTAQGIEATRQEIEENRDWIQQKKKQAQMSEPvgfDSKQAEERLLALKAMLKEAEGKqmvIDTLEKRVGNMQnel 809
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK---QLAALERRIAALARRIRALEQE---LAALEAELAELE--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 810 esNEQQQLENETKALRGE-QSQLCTILTEGISSATVAADARRKFeADLERARSWIKSKSNNLKKLSGYLPLKASKVEQdi 888
Cdd:COG4942 90 --KEIAELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDF-LDAVRRLQYLKYLAPARREQAEELRADLAELAA-- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 889 vqhgeletdidsfSEKDLNDILKQGNNLLKEcSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLLQGRKAFESEID 968
Cdd:COG4942 165 -------------LRAELEAERAELEALLAE-LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
250
....*....|....*.
gi 373194212 969 KCQRWINEAEVATSSD 984
Cdd:COG4942 231 RLEAEAAAAAERTPAA 246
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
10085-10837 |
8.03e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 8.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10085 SKTEQFNILTNQHNETLAKIMERHAAVRDRLAAWDRYKLDQSKLLywlKEIERERSQLRFRFIQIQRLDEILQRIESLLE 10164
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE---QQKQILRERLANLERQLEELEAQLEELESKLD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10165 kipEGEAQLESLQRQQETLLVKCDEALAvtihrDHAASVQRINNLSSSLEMWRDHIPRIQKRYKEYEEKAKEINssftei 10244
Cdd:TIGR02168 334 ---ELAEELAELEEKLEELKEELESLEA-----ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN------ 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10245 gqafstafhsspASLTRTKQQLESVHQMQNRLSSmsvDLESLGVMIQQLREDLSPTDIKSLNEQRALFRLQHEDLEHQAA 10324
Cdd:TIGR02168 400 ------------NEIERLEARLERLEDRRERLQQ---EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10325 LLICRLEERCGLYDRWRDRLARLLAWIGETEIRIQDCDSPNEPEETLKKleceIQSDIALKQRELLWIQNTGQDLVEVAE 10404
Cdd:TIGR02168 465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK----NQSGLSGILGVLSELISVDEGYEAAIE 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10405 EEESERLQRSLDELNERWDRLVA-MGKARASKLMDLMRTMSTLEKRINELRSWLASVESqlsetFVVEAIEQSCIDKKLd 10483
Cdd:TIGR02168 541 AALGGRLQAVVVENLNAAKKAIAfLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG-----FLGVAKDLVKFDPKL- 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10484 dhehlQKTIEAESGNIGEVLNLcEILLNDCDAWKTSFNNAIKSGmEGLERRWTTTcvKSAERKGNIILAWKI-LQELEKI 10562
Cdd:TIGR02168 615 -----RKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDG-DLVRPGGVIT--GGSAKTNSSILERRReIEELEEK 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10563 RLEQEGWLAETDKALAELENNLDEVSKDESKK---AIEKARSISEDVEAHEPVIKIIEQNFGRLARTGLEPDNLKSLISE 10639
Cdd:TIGR02168 686 IEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10640 TRRLIDKWQTFKPRANAVLLALQKGQKNYRdfitvhgaavvgltqvdvrltrtqhlatpEQKASIRRRLQQLNEieeELR 10719
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQLK-----------------------------EELKALREALDELRA---ELT 813
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10720 TQNITLQKadelaLKVMQECHPDDVANIQELVDEYQLLWKDIKKRVASLRAEIEGQEKSEVDEAVQVETLKFEQDSAVQV 10799
Cdd:TIGR02168 814 LLNEEAAN-----LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 373194212 10800 DTLPRLLRMTSS------DAYLMELEAALVECNDALDTLQLAIA 10837
Cdd:TIGR02168 889 LALLRSELEELSeelrelESKRSELRRELEELREKLAQLELRLE 932
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4740-5282 |
9.14e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.52 E-value: 9.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4740 KKEESKETPLLIKELEEKDTTETAELSQIMEQLTAEIKKKEIEEISLLPKESEVIEKKDIDIIETSELTRTMEELITAIK 4819
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAA 1415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4820 EIS-TDEIIDQTEEKKMEKNITEEllTTSQSKTEEEVKPAMESSKIERVGK---ETKSEKNKKKQKKQNEKKEETPVLEN 4895
Cdd:PTZ00121 1416 AKKkADEAKKKAEEKKKADEAKKK--AEEAKKADEAKKKAEEAKKAEEAKKkaeEAKKADEAKKKAEEAKKADEAKKKAE 1493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4896 PIMTEQENIKKIVEKSVSEKKKTSKESKKKEVKEASKEEKIITEEPVKSYPLEK--DINIVTEITETEKLVNGKAIEIID 4973
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEEKKKAEEAKKAE 1573
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4974 LDAIQSSTNQQSSKEGKTKPVEKSKKEETKTKSGKQKQFKEKPDIKPKStsdKELKKQDKQENSSPDSKKKREGKSKKTN 5053
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5054 DIPtpvSQEIVNEISSEEFKKEEnqiEIKQASQEEIQPSVCTKSWASIVSMKGNTETNNSTDISKViPEESISETLKLEK 5133
Cdd:PTZ00121 1651 ELK---KAEEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK-EAEEKKKAEELKK 1723
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5134 IEKVEEIVPEELQNSPAHQKRMKHQKKKDAKQEKNVTEIKVSSTNTENE--GEKEITIEE-----------SQELITKDS 5200
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEirKEKEAVIEEeldeedekrrmEVDKKIKDI 1803
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5201 NKSYAQVAASNKRTSPQFNQ---------EDIIIAKPTPI---------MLNENTEKKEIAQEEALIITEIENvKEETIK 5262
Cdd:PTZ00121 1804 FDNFANIIEGGKEGNLVINDskemedsaiKEVADSKNMQLeeadafekhKFNKNNENGEDGNKEADFNKEKDL-KEDDEE 1882
|
570 580
....*....|....*....|
gi 373194212 5263 SEKEVTMDKKFDELVIEKDI 5282
Cdd:PTZ00121 1883 EIEEADEIEKIDKDDIEREI 1902
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
4012-4333 |
1.07e-04 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 50.22 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4012 PVKLEDSKFKLEEIENKTILNEEKIRDLEKSIEVPVKIETEEvNNKTTIVEEKVIEKGVEVPVDIKSVTKEIEGKITLP- 4090
Cdd:PRK00448 17 PDDLQSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDFK-LFKEKLKQSFSHIADIKVTFSIEVENITFTEELLLDy 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4091 EEKVAEFEKSIEVPIK--INDTKLETEEIKLEDKVDSEkqerIEIEDFKSIMKGIEDKT---DLIEEKLIDTGKREDVSI 4165
Cdd:PRK00448 96 WNEIIEKAKKNSPLFKslLKKQKVEVEGNKLIIKVNNE----IERDHLKKKHLPKLIKQyekFGFGILKIDFEIDDSKEE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4166 KLKKIENKPTQDEEKIKEVPINIKDFESIIEKI-NSETILVEEKDLKEKI--EIPLEIKSITEEvedktalfEEKVVESE 4242
Cdd:PRK00448 172 LEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQsKNFDPKEGPVQIGKKIdkEEITPMKEINEE--------ERRVVVEG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4243 KSFKevpVKIDYSKSQEEIkVEEKIVEKQETIV------NKDFKSKMENIE--DKTILEENIIESEKSIEVLVEVKDSKK 4314
Cdd:PRK00448 244 YVFK---VEIKELKSGRHI-LTFKITDYTSSIIvkkfsrDKEDLKKFDEIKkgDWVKVRGSVQNDTFTRDLVMNAQDINE 319
|
330
....*....|....*....
gi 373194212 4315 IEeevPVEIKDSKSKTKDV 4333
Cdd:PRK00448 320 IK---HPERKDTAEEEKRV 335
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
706-1113 |
1.13e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 706 QQIEEQIKSVERRYADIGKKLQRKAQvldmTAQGIEATRQEIEENRDWIQQKKKQAQMSEPVGfDSKQAEERLLALKAML 785
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREELEKLEKLLQLLPLYQ-ELEALEAELAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 786 KEAEGKQMVIDTLEKRVGNMQNELEsNEQQQLENETKALRGEQSQlctILTEGISSATVAADARRKFEADLERARSWIKS 865
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELA-ELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 866 KSNNLKKLSGYLPLKASKVEQD---------------IVQHGELETDIDSF-------------------SEKDLNDILK 911
Cdd:COG4717 225 LEEELEQLENELEAAALEERLKearlllliaaallalLGLGGSLLSLILTIagvlflvlgllallflllaREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 912 QGNNLLKECSEEDRARLNKILDELNKDYEELKSEAQE---KQAALADLLQGRKAFESEIDKCQRWINEAEVATSSDVrtS 988
Cdd:COG4717 305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLElldRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV--E 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 989 SIDILREQLAKYDRLKKEANEYADDIEKLMQQGKSILPTVTDADKLELNEQLQNmkeahgrvagiINERALALQKNIDEA 1068
Cdd:COG4717 383 DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEE-----------LEEELEELEEELEEL 451
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 373194212 1069 EESLARVAEAIQYMTDvQKELHELNKPIGSRVEDVEAMLDAYERI 1113
Cdd:COG4717 452 REELAELEAELEQLEE-DGELAELLQELEELKAELRELAEEWAAL 495
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2844-3407 |
1.39e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 49.63 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2844 SEYSKEKLQKEKIKinmeqqKQVFETKDEIVVEDT--SKINVKNNEVEIKKEKVEDVQpekrvdvektKKIEAQKQDEKQ 2921
Cdd:TIGR04523 124 VELNKLEKQKKENK------KNIDKFLTEIKKKEKelEKLNNKYNDLKKQKEELENEL----------NLLEKEKLNIQK 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2922 EIQEEKHdvqQRSRSQEK----KRKGKKKKPEKSMDDEIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDi 2997
Cdd:TIGR04523 188 NIDKIKN---KLLKLELLlsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN- 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2998 ekkgvkpgEKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIEKrNAKDEAKISKEKVESRKNESEKRS 3077
Cdd:TIGR04523 264 --------KIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK-ELKSELKNQEKKLEEIQNQISQNN 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3078 EIKIDSSSEMRKIetKEEKAQKDSANLSKKKQKGKEQTGTVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQKEKDI 3157
Cdd:TIGR04523 335 KIISQLNEQISQL--KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3158 KPVENIGNLDQLQKQ-EDTKSVKLMKSEKISETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQKEE 3236
Cdd:TIGR04523 413 QIKKLQQEKELLEKEiERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3237 KKTEQSKQKKSVEK---SEVIDIKLEENEKIKIEIDVKAPKDEKEKKITGKEKEKKSESKDRKKKDIKPEVALKEKAKEE 3313
Cdd:TIGR04523 493 SKEKELKKLNEEKKeleEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEE 572
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3314 QKAIINPLINA-IESDKKIEEKEIDNKDSKESSTPKkeMKKAGEAEKQIKTKGGKKSKKEADI-NQKPATEIIKKE---- 3387
Cdd:TIGR04523 573 LKQTQKSLKKKqEEKQELIDQKEKEKKDLIKEIEEK--EKKISSLEKELEKAKKENEKLSSIIkNIKSKKNKLKQEvkqi 650
|
570 580
....*....|....*....|....
gi 373194212 3388 ----ETIIVDKQIIEEKIDEKIII 3407
Cdd:TIGR04523 651 ketiKEIRNKWPEIIKKIKESKTK 674
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
241-811 |
1.45e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.55 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 241 ERYKHIQEEVRGKKTELDHLMDEA--SELSKLAKKNTPLERTKELLKRWENLSENVDERKRL-IENEMQEYNAYHAALQE 317
Cdd:COG1196 213 ERYRELKEELKELEAELLLLKLREleAELEELEAELEELEAELEELEAELAELEAELEELRLeLEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 318 TEKWLLQISFQLMAHNSLYITNKEQTVSQIQQHENLLVEIENYTSVLNDLKLKGNGQITRYVAVNSEIKTI------IET 391
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAeealleAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 392 QLQNVQESYNSLLNTALQIKKRLAESLIKFQEYENTLESIMKNLDAYEPEIAQEMEAPMDTL---DAAKQRFENARMLHN 468
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEeeeEEEEEALEEAAEEEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 469 KLQGEKTRLALAVEACEAAVACVSRPGSPLDAPPvqipAREVEVRNKLEELIDQAQGHLMNVtKALNELEEQTRQKNVLR 548
Cdd:COG1196 453 ELEEEEEALLELLAELLEEAALLEAALAELLEEL----AEAAARLLLLLEAEADYEGFLEGV-KAALLLAGLRGLAGAVA 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 549 AWInqqralcaEWKSRPAKLRSEAALAELQAMNDLLGNVGERRTHAL--------TELSLHEDDQDIEEGLNKLEAELTD 620
Cdd:COG1196 528 VLI--------GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaakagraTFLPLDKIRARAALAAALARGAIGA 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 621 AIAGKQAAQDLIQKYRTQVQnmqswlDTLSKKVDVIEKGNGQTIGQKIASVKEITTEFESQGPGKLNEVKTLSDQVMDSV 700
Cdd:COG1196 600 AVDLVASDLREADARYYVLG------DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 701 SNLDSQQIEEQIKSVERRYADIGKKLQRKAQVLDMTAQGIEATRQEIEENRDWIQQKKKQAQMSEpvgfdsKQAEERLLA 780
Cdd:COG1196 674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL------EELLEEEEL 747
|
570 580 590
....*....|....*....|....*....|.
gi 373194212 781 LKAMLKEAEGKQMVIDTLEKRVGNMQNELES 811
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
10851-11037 |
2.20e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 47.06 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10851 KNISKLIGSCQSSIELVRHLHSLLIEDGKLSAQAAKAnEVAALTERYENLLILARTREQQIRELSDngrltcplcsrrnW 10930
Cdd:cd00176 43 EALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQE-RLEELNQRWEELRELAEERRQRLEEALD-------------L 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10931 AQLENDLWRLEKWLEFAEGTQSAQhSPPGNIEQLEDVIQDHREFVLDLDCHESILASLNTVGAHLADHtEELLRATQLRD 11010
Cdd:cd00176 109 QQFFRDADDLEQWLEEKEAALASE-DLGKDLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEE-GHPDADEEIEE 186
|
170 180
....*....|....*....|....*..
gi 373194212 11011 RLAVANTRWVKVCKVAAHWQEQLQTAL 11037
Cdd:cd00176 187 KLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2910-3480 |
2.24e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.91 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2910 KKIEAQKQDEKQEIQEEKhDVQQRSRSQEKKRKGKKKKPEKSMDDEIDKAlkeiEDMDKQKKRDKSREQTKIKDTTQTVQ 2989
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTE-NIEELIKEKEKELEEVLREINEISSELPELR----EELEKLEKEVKELEELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2990 TEKYKEDIEKKGVKPGEKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIEKRNAKDEakisKEKVESR 3069
Cdd:PRK03918 247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR----LSRLEEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3070 KNESEKRSEIKIDSSSEMRKIETKEEKAQKDSANLSKKKQKGKEqtgTVKDKSNKDSVKSTKTENESEQMKKAI--FIED 3147
Cdd:PRK03918 323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE---AKAKKEELERLKKRLTGLTPEKLEKELeeLEKA 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3148 KTEIQKEKDiKPVENIGNLDQLQKQEDTKSVKLMKSEKISET---KVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKD 3224
Cdd:PRK03918 400 KEEIEEEIS-KITARIGELKKEIKELKKAIEELKKAKGKCPVcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKL 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3225 QTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEKIKIEIDVKAPKDEKEKKITGKEKEKKSESKDRKKKDIKPEV 3304
Cdd:PRK03918 479 RKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKL 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3305 ALKEKAKEEQKAIINPLINAIESdKKIEEKEIDNKDSKESSTPKKEMKKAGEAEKQIKTKGGKKSKKEADInqkpaTEII 3384
Cdd:PRK03918 559 AELEKKLDELEEELAELLKELEE-LGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-----DKAF 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3385 KKEETIIVDKQIIEEKIDEKIII------EESKKEHLKLESvvpntEQSEMKKHKKSKSPKRGKKEENLKFVEKEKTEKK 3458
Cdd:PRK03918 633 EELAETEKRLEELRKELEELEKKyseeeyEELREEYLELSR-----ELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
570 580
....*....|....*....|..
gi 373194212 3459 ETQGETIKLEEISDKIDNTKEK 3480
Cdd:PRK03918 708 KAKKELEKLEKALERVEELREK 729
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
2832-3395 |
2.45e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 48.89 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2832 KTKIPEKRARRGSEYSKEKLQKEKIKINMEQQKQVFET------------------KDEIVVEDTSKINVKNNEveikKE 2893
Cdd:TIGR01612 785 KSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTisikedeifkiinemkfmKDDFLNKVDKFINFENNC----KE 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2894 KVEDvqpEKRVDVEKTKKIEAQKQDEKQEIQEEKHDvQQRSRSQEKKRKGKKKKPEKSMDDEIDKALKEIEDMDKQKKRD 2973
Cdd:TIGR01612 861 KIDS---EHEQFAELTNKIKAEISDDKLNDYEKKFN-DSKSLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKF 936
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2974 KSReQTKIKDT-TQTVQTEKYKEDIEKKGVKPGEKKKQNK-SKMEKIRDESEIAMNQANAKEQMKSKNDTKES----KEE 3047
Cdd:TIGR01612 937 HNK-QNILKEIlNKNIDTIKESNLIEKSYKDKFDNTLIDKiNELDKAFKDASLNDYEAKNNELIKYFNDLKANlgknKEN 1015
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3048 KNIEKRNAKDEAKISKEKVESRKNESEKRSEIKIDSS-----SEMRKIETKE---------EKAQKDSANLSKKKQKGKE 3113
Cdd:TIGR01612 1016 MLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSiyniiDEIEKEIGKNiellnkeilEEAEINITNFNEIKEKLKH 1095
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3114 QtgTVKDKSNKDSVKSTkteNESEQMKKAIFIEDKteiQKEKDIKPVENIGNldQLQKQEDTKSVKLMKSEKISETKVES 3193
Cdd:TIGR01612 1096 Y--NFDDFGKEENIKYA---DEINKIKDDIKNLDQ---KIDHHIKALEEIKK--KSENYIDEIKAQINDLEDVADKAISN 1165
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3194 KEKEPAKPKEqdkskknkkqkqgtENEVSKdqTPKKQSQQKEEKK-----TEQSKQKKSVEKSEVIDIKLEEN------E 3262
Cdd:TIGR01612 1166 DDPEEIEKKI--------------ENIVTK--IDKKKNIYDEIKKllneiAEIEKDKTSLEEVKGINLSYGKNlgklflE 1229
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3263 KIkieidvkapkDEKEKKitgkekekksesKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSK 3342
Cdd:TIGR01612 1230 KI----------DEEKKK------------SEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDK 1287
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 3343 ESSTPKKEMKKAGEAEKQIKTKGGKKSKKEADINqkpatEIIKKEETIIVDKQ 3395
Cdd:TIGR01612 1288 DHHIISKKHDENISDIREKSLKIIEDFSEESDIN-----DIKKELQKNLLDAQ 1335
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
2951-3382 |
2.69e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 48.47 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2951 SMDDEIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDIEKKGVKpGEKKKQNKSKMEKIrdeSEIAMNQAN 3030
Cdd:NF033838 50 SSGNESQKEHAKEVESHLEKILSEIQKSLDKRKHTQNVALNKKLSDIKTEYLY-ELNVLKEKSEAELT---SKTKKELDA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3031 AKEQMKsKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKN---ESEKRSEIKIDSSsemrkietkEEKAQKDSANLSKK 3107
Cdd:NF033838 126 AFEQFK-KDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRRNyptNTYKTLELEIAES---------DVEVKKAELELVKE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3108 KqkgkeqtgtVKDKSNKDSVKSTKTENESEQMKKAIFIEDKTEIQK-EKDIKPVENIGNLDQLQKQEDTKSvklmKSEKI 3186
Cdd:NF033838 196 E---------AKEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKaEEEAKRRADAKLKEAVEKNVATSE----QDKPK 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3187 SETKVESKeKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEENEKIKI 3266
Cdd:NF033838 263 RRAKRGVL-GEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLEL 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3267 EI---DVKAPKDEKEkkitgkekekksESKDRKKKDIKPEVALKEKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKE 3343
Cdd:NF033838 342 EIaesDVKVKEAELE------------LVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRKAAEE 409
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 373194212 3344 SSTPKK--EMKKAGEAEKQIKTKGGKKSKKEADINQKPATE 3382
Cdd:NF033838 410 DKVKEKpaEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQ 450
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1374-1582 |
3.06e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 46.67 E-value: 3.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1374 QEYAALTEKLRSWVREAEIRLESDKDGLDFENILSDLEEHKIyFSSEPSIRELVSQQIQQAGDKIwPSLNTSEQEELSAE 1453
Cdd:cd00176 3 QQFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEA-LEAELAAHEERVEALNELGEQL-IEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1454 QQQHTQLLKNTLNTAKSQRARLEQGAETWRDYTQTLERVRAVIARSRF--TDEPVTTLAGLQFNIQKITHALNDIQNQQF 1531
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAAlaSEDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 373194212 1532 ELDLLIERSQEVLRLADANNKKTIEAQISEISAEWKELVSGLEGRRDALEA 1582
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
922-1724 |
3.22e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.51 E-value: 3.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 922 EEDRARLNKILDELNKDYEELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAeVATSSDVrTSSIDILREQLAkyd 1001
Cdd:TIGR02168 238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL-ANEISRL-EQQKQILRERLA--- 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1002 RLKKEANEYADDIEKLMQQgksilptvtdadKLELNEQLQNMKEAHGRVAGIINERALALQKNIDEAEESLARVAEAIQY 1081
Cdd:TIGR02168 313 NLERQLEELEAQLEELESK------------LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1082 MTDVQKELHELNKpigsRVEDVEAMLDAYERILNDLKANKAKLSDLQSINVADLHgvLTQQDDLMKAIESQIAKLRQLLL 1161
Cdd:TIGR02168 381 LETLRSKVAQLEL----QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1162 LRQQFIALITEITTFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIAAEGSTV-DRNNITEQ 1240
Cdd:TIGR02168 455 ELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEG 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1241 LQSLKQQLQGLRR-AVETQREQHELAAAEH---KRLANELAEILDWLEDKEKEVKSRPLLER---------DPISVEAEL 1307
Cdd:TIGR02168 535 YEAAIEAALGGRLqAVVVENLNAAKKAIAFlkqNELGRVTFLPLDSIKGTEIQGNDREILKNiegflgvakDLVKFDPKL 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1308 QKhnelcdAVNEHLDRIR---------NLKNSVPHEE----------GMPGSLKEMLSEAVSLLTSLPREMEErgnyles 1368
Cdd:TIGR02168 615 RK------ALSYLLGGVLvvddldnalELAKKLRPGYrivtldgdlvRPGGVITGGSAKTNSSILERRREIEE------- 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1369 nmkLRQEYAALTEKLRswvrEAEIRLESDKDglDFENILSDLEEHKiyfssepsiRELVSQQIQQAGDKIWPSLNTSEQE 1448
Cdd:TIGR02168 682 ---LEEKIEELEEKIA----ELEKALAELRK--ELEELEEELEQLR---------KELEELSRQISALRKDLARLEAEVE 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1449 ELSAEQQQHTQLLKNTLNTAKSQRARLEQGAETWRDYTQTLERVRAVIArsRFTDEPVTTLAGLQfNIQKITHALN-DIQ 1527
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE--QLKEELKALREALD-ELRAELTLLNeEAA 820
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1528 NQQFELDLLIERSQEVLRLAD--ANNKKTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWSLIETKVTAIE 1605
Cdd:TIGR02168 821 NLRERLESLERRIAATERRLEdlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS 900
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1606 EKGKLLDTVVRSKQHLYD-TIKSLHELVTEAEKLKPMAAEVKA-------LSGPVLAYLAAFTEAPAHALEEKLNKLQNS 1677
Cdd:TIGR02168 901 EELRELESKRSELRRELEeLREKLAQLELRLEGLEVRIDNLQErlseeysLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 373194212 1678 VESL-------IDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLY 1724
Cdd:TIGR02168 981 IKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERF 1034
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1515-2036 |
3.30e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 3.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1515 NIQKITHALNDIQNQQFELDLLIERSQEVL-RLADANNK-KTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEA 1592
Cdd:PRK03918 156 GLDDYENAYKNLGEVIKEIKRRIERLEKFIkRTENIEELiKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1593 QWSLIETKVtaiEEKGKLLDTVVRSKQHLYDTIKSLHELVTEAEKLKPMAAEVKALSGPVLAY--LAAFTEAPAHALEEk 1670
Cdd:PRK03918 236 LKEEIEELE---KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYikLSEFYEEYLDELRE- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1671 LNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERAsnlyifgpdqdateEELDELRWAVEQLLES 1750
Cdd:PRK03918 312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERH--------------ELYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1751 GKKFSGSTkaryqasqqlvPSDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLDEvqawIRQAELK--VQD 1828
Cdd:PRK03918 378 KKRLTGLT-----------PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE----LKKAKGKcpVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1829 RSIEPVPLKDQLRQVQEELGTITDKLERLTRNGRTIAENTRDDTEKQLIDSTVHNVTEQLNQVRNWLDERKQVVADTIDA 1908
Cdd:PRK03918 443 RELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEK 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1909 -WQRFLSLYEAVRTWTEEKRQFLVEPLKLSTLVQARQRLHeystavKSCKQINKNLSDMGKELESIGqVCSVGDLPEKLL 1987
Cdd:PRK03918 523 kAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE------KKLDELEEELAELLKELEELG-FESVEELEERLK 595
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 1988 EAEEAK------VQVEGQLLERNALLQETSEEWEQCERKMKEVKTWIEKAKQSLE 2036
Cdd:PRK03918 596 ELEPFYneylelKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
9713-9912 |
3.33e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 46.28 E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 9713 LWRRFEKQLEMVQQSVQEAdyMMELLTVQGSVDYDRLLKATERLEGLSGDLGAREVLIGELREAAEPLREGCAAEVrEKV 9792
Cdd:cd00176 1 KLQQFLRDADELEAWLSEK--EELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDA-EEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 9793 EAAVNEAVQAWEDTRAELDALCTKYQHACRLWQQYKDSSaAVKAWVDTQMDSVANLPP-------EEAVKHIKVCEETMA 9865
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLgkdlesvEELLKKHKELEEELE 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 373194212 9866 EHKERLAELQGLVAQIASDVGLDASGPLHCEVEALGQRLEDIRETLS 9912
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAE 203
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
212-303 |
3.61e-04 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 43.85 E-value: 3.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:pfam00435 13 LESWIEEKEALLSS-EDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASEEiqERLEELNERWEQ 91
|
90
....*....|....
gi 373194212 290 LSENVDERKRLIEN 303
Cdd:pfam00435 92 LLELAAERKQKLEE 105
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4135-5112 |
3.61e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 3.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4135 DFKSIMKGIEDKTDLIEEKLIDTGKredvsiklkKIENKPTQDEEKIKEVPINIKDFESIIEKINSETILVEEKDLKEKI 4214
Cdd:PTZ00121 1080 DFDAKEDNRADEATEEAFGKAEEAK---------KTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED 1150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4215 EIPLEIKSITEEVEdktalfeeKVVESEKSfkEVPVKIDYSKSQEEIKVEEKiVEKQETIVNKDFKSKMENIedKTILEE 4294
Cdd:PTZ00121 1151 AKRVEIARKAEDAR--------KAEEARKA--EDAKKAEAARKAEEVRKAEE-LRKAEDARKAEAARKAEEE--RKAEEA 1217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4295 NIIESEKSIEVLVEVKDSKKIEEEVpveiKDSKSKTKDVNPYYFTDLVKPYWFNYRPYIKAEIDfyRHFKIVKILEENVP 4374
Cdd:PTZ00121 1218 RKAEDAKKAEAVKKAEEAKKDAEEA----KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKK 1291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4375 APVLPRSDSIERIVQesiMKNSKEEEKKIESAEQSETEYTNASQEIiKEKSKETENKTKDTKESETEYKHVLQESIEEKS 4454
Cdd:PTZ00121 1292 ADEAKKAEEKKKADE---AKKKAEEAKKADEAKKKAEEAKKKADAA-KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4455 KKIEKKTEDIEESEAEYRKyaliGETFKYPISTFYKLESEWVKSKLIQEKEVTLIPVEESESTNPEINKEiiqiyEEEKL 4534
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAAKKK----AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA-----DEAKK 1438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4535 PIELKELEEVIPTSVEESKltdvevkspiKSEELEVKnekvtlssGEESKPIEvEIKKEIIEIYEGEKPTLKLEEDKKii 4614
Cdd:PTZ00121 1439 KAEEAKKADEAKKKAEEAK----------KAEEAKKK--------AEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKK-- 1497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4615 niEKDTMKVIEEVTteikstdrildqtaaliedltKELDMIKKEEEQNKivtiveeRKKESEAEKKEQVSEKKSKTEKSK 4694
Cdd:PTZ00121 1498 --KADEAKKAAEAK---------------------KKADEAKKAEEAKK-------ADEAKKAEEAKKADEAKKAEEKKK 1547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4695 KEKQSKSEKSKDKkkeisiKEHEVIEEKDIVETEMTQIIEQLTEIKKEESKETPLLIKELEEKDTTETAELSQIMEQLTA 4774
Cdd:PTZ00121 1548 ADELKKAEELKKA------EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4775 EIKkkeieeislLPKESEVIEKKDIDIIETSELTRTMEELITAIKE--ISTDEIIDQTEEKKMEKNITEELLTTSQSKTE 4852
Cdd:PTZ00121 1622 AEE---------LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEnkIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4853 EEVKPAMESSKIERVGKETKSEKNKKKQKKQNEKKEETPVlENPIMTEQENIKKIVEKSVSEKKKTSKESKKKEVKEASK 4932
Cdd:PTZ00121 1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4933 EEKIITEEPVKSYPLEKDINIVTEITETEKLVNGKAIEIIDLDAIQSS--TNQQSSKEGKTKPVEKSKKEETKTKSGKQK 5010
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLviNDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5011 QFKEKPDIKPKSTSdkelkkQDKQENSSPDSKKKREGKSKKTNDIPTPVSQEIVNEISSEEFKKEENQIEIKQASQEEIQ 5090
Cdd:PTZ00121 1852 HKFNKNNENGEDGN------KEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYI 1925
|
970 980
....*....|....*....|..
gi 373194212 5091 PSVCTKSWASIVSMKGNTETNN 5112
Cdd:PTZ00121 1926 KRDAEETREEIIKISKKDMCIN 1947
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3510-4415 |
4.14e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 4.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3510 IMQTDKIEIQSAIEKIPEKIIVEGSMETFTETVEIAKETEKVKVSDTKEERETPLSEISKTEELEDQQPEQKSEMPSTLK 3589
Cdd:pfam02463 138 LVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKE 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3590 NKKSNKSKEK------HPIEKVTPLSIVQEPKPNTSKSQPSTPKSDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKS 3663
Cdd:pfam02463 218 KLELEEEYLLyldylkLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEE 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3664 IEESIEIPDVASEKSIFKEKEISTTLQPEIIpIIESEKDQIIEIDESKSFSQDLIEKPSTEEVPSLSLTEEILNVtdtgs 3743
Cdd:pfam02463 298 LKSELLKLERRKVDDEEKLKESEKEKKKAEK-ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL----- 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3744 piEKSSSTSSGKALIIERTVTTVTTTTSMPGSVEVKPPNVKSMKSVEILESIPLPKIVGSKPTELITLRPETVEASLTTR 3823
Cdd:pfam02463 372 --EEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3824 YARISDDSAvgipsKEFLDMLADESNFDYANYINLVEDDQPILFGSvQDRRKDRSGTPLSAKSVENAKDEREVDDLKEGQ 3903
Cdd:pfam02463 450 KEELEKQEL-----KLLKDELELKKSEDLLKETQLVKLQEQLELLL-SRQKLEERSQKESKARSGLKVLLALIKDGVGGR 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3904 GVDAKISQDTLGENEGKAEkgemmVKKEVNVFEkiESERFKDSRELVVENEDKSVKEKQETNKTVEELLFTVGKGEDVKN 3983
Cdd:pfam02463 524 IISAHGRLGDLGVAVENYK-----VAISTAVIV--EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV 596
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3984 AVEELLEAERQAMVVEQKIVDIEKGETVPVKLEDSKFKLEEIENKTILNEEKIRD--LEKSIEVPVKIETEEVNNKTTIV 4061
Cdd:pfam02463 597 LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGvsLEEGLAEKSEVKASLSELTKELL 676
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4062 EEKVIEKGVEVPVDIKSVTKEIEGKITLPEEKVAEFEKSIEVPIKINDTKLETEEIKLEDKVDSEKQERIEI--EDFKSI 4139
Cdd:pfam02463 677 EIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeEEEKSR 756
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4140 MKGIEDKTDLIEEKLIDTG--KREDVSIKLKKIENKPTQDEEKIKEVPINIKDFESIIEKINSETILVEEKDLKEKIEIP 4217
Cdd:pfam02463 757 LKKEEKEEEKSELSLKEKElaEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELE 836
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4218 LEIKSITEEVEDKTALFEEKVVESEKSFKEVpvkidYSKSQEEIKVEEKIVEKQETIVNKDFKSKMENIEDKTILEENII 4297
Cdd:pfam02463 837 ELALELKEEQKLEKLAEEELERLEEEITKEE-----LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL 911
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4298 ESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYYFTDLVKPYWFNYRPYIKAEIDFYRHFKIVKILEENVpapv 4377
Cdd:pfam02463 912 LEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE---- 987
|
890 900 910
....*....|....*....|....*....|....*...
gi 373194212 4378 lprsdsiERIVQESIMKNSKEEEKKIESAEQSETEYTN 4415
Cdd:pfam02463 988 -------ERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1467-2042 |
4.38e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 4.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1467 TAKSQRARLEQGAETWRDYTQTLERVRAVIARsrftdepvttLAGLqfniqkithalnDIQNQQFELDLLIERSQEVLRL 1546
Cdd:COG4913 246 DAREQIELLEPIRELAERYAAARERLAELEYL----------RAAL------------RLWFAQRRLELLEAELEELRAE 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1547 ADANnkktiEAQISEISAEWKElvsgLEGRRDALEAlsKHW-------EDLEAQwslietkvtaIEEKGKLLDTVVRSKQ 1619
Cdd:COG4913 304 LARL-----EAELERLEARLDA----LREELDELEA--QIRgnggdrlEQLERE----------IERLERELEERERRRA 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1620 HLYDTIKSLH-ELVTEAEKLKPMAAEVKALSGPVLAYLAAFTEApAHALEEKLNKLQNSVESLIDTLqtkskkadEDLET 1698
Cdd:COG4913 363 RLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEEA-LAEAEAALRDLRRELRELEAEI--------ASLER 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1699 FEST-EREIDQLRKRLNEA-RERASNLYIFGpdqdateeEL-----DELRW--AVEQLLesgkkfsgstkaRYQASQQLV 1769
Cdd:COG4913 434 RKSNiPARLLALRDALAEAlGLDEAELPFVG--------ELievrpEEERWrgAIERVL------------GGFALTLLV 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1770 P----SDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLD----EVQAWIRQ--------------AELKVQ 1827
Cdd:COG4913 494 PpehyAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDfkphPFRAWLEAelgrrfdyvcvdspEELRRH 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1828 DRSIEPVPL---------KDQLRQVQEE--LG-TITDKLERLTRNgRTIAENTRDDTEKQLidSTVHNVTEQLNQVRNWL 1895
Cdd:COG4913 574 PRAITRAGQvkgngtrheKDDRRRIRSRyvLGfDNRAKLAALEAE-LAELEEELAEAEERL--EALEAELDALQERREAL 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1896 DERKQVVADTIDAWQrflsLYEAVRTWTEEKRQFLVEPLKLSTLVQARQRLH-EYSTAVKSCKQINKNLSDMGKELESIg 1974
Cdd:COG4913 651 QRLAEYSWDEIDVAS----AEREIAELEAELERLDASSDDLAALEEQLEELEaELEELEEELDELKGEIGRLEKELEQA- 725
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1975 qvcsvgdlpEKLLEAEEAKVQ--VEGQLLERNALLQETSEEwEQCERKMKEVKTWIEKAKQSLESPQNKK 2042
Cdd:COG4913 726 ---------EEELDELQDRLEaaEDLARLELRALLEERFAA-ALGDAVERELRENLEERIDALRARLNRA 785
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2854-3427 |
4.81e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2854 EKIKINMEQQKQVFETKDEIVVEDTSKINVKNNEVEIKKEKVEDVQPE-------------------KRVDVEKTKKIEA 2914
Cdd:TIGR04523 43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKlkknkdkinklnsdlskinSEIKNDKEQKNKL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2915 QKQDEKQEIQEEKHDVQQRSRSQEKKRKGKKKKPEKSMDDEIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYK 2994
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2995 EDIEKKGVkpgEKKKQNKSKMEKIRDESEIAMNQANAKEQMKSKNDTKESKEEKNIEkrNAKDEAKISKEKVESRKNESE 3074
Cdd:TIGR04523 203 LSNLKKKI---QKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN--QLKDEQNKIKKQLSEKQKELE 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3075 KRSEIKIDSSSEMRKIET--------KEEKAQKDSANLSKKKQKGKEQTGTVKDKSNK---------DSVKSTKTENESE 3137
Cdd:TIGR04523 278 QNNKKIKELEKQLNQLKSeisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKiisqlneqiSQLKKELTNSESE 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3138 QMKKAIFIEDKTE----IQKEKDIKpVENIGNLDQLQKQEDTKSVKLMKSEKISETKVESKEKE-PAKPKEQDKSKKNKK 3212
Cdd:TIGR04523 358 NSEKQRELEEKQNeiekLKKENQSY-KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEkELLEKEIERLKETII 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3213 QKQGTENEVSKDQTPKKQSQQKEEKKTEQSKQKKSVEKSEVIDIKLEEnEKIKIEIdvkapkDEKEKKItgkekekksES 3292
Cdd:TIGR04523 437 KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNL-EQKQKEL------KSKEKEL---------KK 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3293 KDRKKKDIKPEValkeKAKEEQKAIINPLINAIESDKKIEEKEIDNKDSKESStpKKEMKKAGEAEKQIKTKGGKKSKKE 3372
Cdd:TIGR04523 501 LNEEKKELEEKV----KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK--DDFELKKENLEKEIDEKNKEIEELK 574
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 373194212 3373 ADI-----NQKPATEIIKKEETIIVDkqiIEEKIDEKII--------IEESKKEHLKLESVVPNTEQS 3427
Cdd:TIGR04523 575 QTQkslkkKQEEKQELIDQKEKEKKD---LIKEIEEKEKkisslekeLEKAKKENEKLSSIIKNIKSK 639
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
5569-5994 |
5.15e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 5.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5569 TQEKIAEKSKIETKEQSSVKKNKKSKKGKSDKDQSKHEFKDKEQDKQIDNAQTTEVELKLKDEITKESEIKDQEEA---K 5645
Cdd:TIGR04523 231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwnK 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5646 ENISEIKSKEIQEKSNENIFDNESEL---LQETKSDKSMQSEKRKKKSKERKVEIAPKQV-IETFIEENKVLESEIQKEI 5721
Cdd:TIGR04523 311 ELKSELKNQEKKLEEIQNQISQNNKIisqLNEQISQLKKELTNSESENSEKQRELEEKQNeIEKLKKENQSYKQEIKNLE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5722 LKEQSEAKDIQDIKATTELVQETIYEKPTSsgkrKGKSKEKKKAITTEIAIKEKEVSRPEIKEILKKESDIEEIKEIEEI 5801
Cdd:TIGR04523 391 SQINDLESKIQNQEKLNQQKDEQIKKLQQE----KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5802 EEKLKTIMKSEDEYKSE---IVQETKSKKSEFSEKNKEKSKEEEITKISIEKKKLPELKIKENTAEISL---------EQ 5869
Cdd:TIGR04523 467 ETQLKVLSRSINKIKQNleqKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEkeskisdleDE 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5870 IIEISIEKNKPEIKGKISEKELEIEEdkeiQKEVQTSIKCEIENKPEVVQETKFEKSPKKRKGKSKETKIETISEQITKI 5949
Cdd:TIGR04523 547 LNKDDFELKKENLEKEIDEKNKEIEE----LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA 622
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 373194212 5950 SIDEKKLSEFEAKEEISSQIKEEEI--IKQKRDDTDHTKQDITKENE 5994
Cdd:TIGR04523 623 KKENEKLSSIIKNIKSKKNKLKQEVkqIKETIKEIRNKWPEIIKKIK 669
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
4163-4442 |
6.46e-04 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 47.47 E-value: 6.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4163 VSIKLKKIENKPTQ-----------DEEKIKEVPINIKDFESIIEKInsetILVEEKDLKEKIE--------IPLEIKSI 4223
Cdd:PTZ00341 849 VDISLSDIENTAKNaaeqilsdeglDEKKLKKRAESLKKLANAIEKY----AGGGKKDKKAKKKdakdlsgnIAHEINLI 924
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4224 TEEVEDKTALFEEKVVESEKSFKEVPVKIDYSKSQEEiKVEEKIVEKQETIVNKDFKskmENIEDKtiLEENIiesEKSI 4303
Cdd:PTZ00341 925 NKELKNQNENVPEHLKEHAEANIEEDAEENVEEDAEE-NVEENVEENVEENVEENVE---ENVEEN--VEENV---EENV 995
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4304 EVLVEVKDSKKIEEEVPVEIKDSKSKTKDVNPYYFTDLVKPYWFNYRPYIKAEIDFYRHFKIVKILEENVPAPVLPRSDS 4383
Cdd:PTZ00341 996 EENVEENIEENVEENVEENIEENVEEYDEENVEEVEENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIEEN 1075
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 373194212 4384 IERIVQESIMKNSKEEEKKIEsaEQSETEYTNASQEIIKEKSKET--ENKTKDTKESETEY 4442
Cdd:PTZ00341 1076 IEENIEENVEENVEENVEEIE--ENVEENVEENAEENAEENAEENaeEYDDENPEEHNEEY 1134
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
850-953 |
7.30e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 43.09 E-value: 7.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 850 RKFEADLERARSWIKSKSNNLKKLSgyLPLKASKVEQDIVQHGELETDIDSFSEKdLNDILKQGNNLLKEcSEEDRARLN 929
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASED--LGKDLESVEALLKKHEAFEAELEAHEER-VEALNELGEQLIEE-GHPDAEEIE 76
|
90 100
....*....|....*....|....
gi 373194212 930 KILDELNKDYEELKSEAQEKQAAL 953
Cdd:smart00150 77 ERLEELNERWEELKELAEERRQKL 100
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
3895-4334 |
1.10e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.60 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3895 EVDDLKEGQGVDAKISQDTLG-ENEGKAEKGEMMVKKEVNvfEKIES-----ERFKDSRELVVENEDKSVKEKQETNKTV 3968
Cdd:PRK03918 136 EIDAILESDESREKVVRQILGlDDYENAYKNLGEVIKEIK--RRIERlekfiKRTENIEELIKEKEKELEEVLREINEIS 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3969 EELLFTVGKGEDVKNAVEELleaERQAMVVEQKIVDIEKGETVPVKLEDSKFKLEEIENKTilnEEKIRDLEKSIEVPVK 4048
Cdd:PRK03918 214 SELPELREELEKLEKEVKEL---EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL---KKEIEELEEKVKELKE 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4049 IETeevnnkttivEEKVIEKGVEVPVDIKSVTKEIEGKITLPEEKVAEFEKSIEvpiKINDTKLETEEIKLEDKVDSEKQ 4128
Cdd:PRK03918 288 LKE----------KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK---ELEEKEERLEELKKKLKELEKRL 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4129 ERIE-----IEDFKSIMKGIEDKTDLIEEKLIdtgkrEDVSIKLKKIENKPTQDEEKIKEVPINIKDFESIIEKINSETI 4203
Cdd:PRK03918 355 EELEerhelYEEAKAKKEELERLKKRLTGLTP-----EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4204 LVEekdlKEKIEIPLEIKSITEevEDKTALFEEKVVESEKSFKEVpVKIDYSKSQ---EEIKVEEKIVEKQETIVNKDFK 4280
Cdd:PRK03918 430 ELK----KAKGKCPVCGRELTE--EHRKELLEEYTAELKRIEKEL-KEIEEKERKlrkELRELEKVLKKESELIKLKELA 502
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4281 SKMENIEDKTI------LEENIIESEKSIEVLVEVKDSKKIEEEVPVEIKDSKSKTKDVN 4334
Cdd:PRK03918 503 EQLKELEEKLKkynleeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE 562
|
|
| COG4995 |
COG4995 |
Uncharacterized conserved protein, contains CHAT domain [Function unknown]; |
1422-1840 |
1.51e-03 |
|
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
Pssm-ID: 444019 [Multi-domain] Cd Length: 711 Bit Score: 46.12 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1422 SIRELVSQQIQQAGDKIWPSLNTSEQEELSAEQQQHTQLLKNTLNTAKSQRARLEQGAETWRDYTQTLERVRAVIARSRF 1501
Cdd:COG4995 27 LLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLAAALALALAAAALAAL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1502 TDEPVTTLAGLQFNIQKITHALNDIQNQQFELDLLIERSQEVLRLADANNKKTIEAQISEISAEWKELVSGLEGRRDALE 1581
Cdd:COG4995 107 ALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAAAAALLALALALAAAALALLALLLAA 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1582 ALSKHWEDLEAQWSLIETKVTAIEEKGKLLDTVVRSKQHLYDTIKSLHELVTEAEKLKPMAAEVKALSGPVLAYLAAFTE 1661
Cdd:COG4995 187 LAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAALAAAAAALLALAAALLL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1662 APAHALEEKLNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLYIFGPDQDATEEELDELR 1741
Cdd:COG4995 267 LAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAALALLALLLLLAAAALLA 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1742 WAVEQLLESGKKFSGSTKARYQASQQLVPSDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLDEVQAWIRQ 1821
Cdd:COG4995 347 AALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAAQLLRLLLAALALLLALAAYA 426
|
410
....*....|....*....
gi 373194212 1822 AELKVQDRSIEPVPLKDQL 1840
Cdd:COG4995 427 AARLALLALIEYIILPDRL 445
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1467-1720 |
1.52e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1467 TAKSQRARLEQGAetwrdytQTLERVRAVIARSrftdepVTTLAGLQFNIQKITHALNDIQNQQF-ELDLL-----IERS 1540
Cdd:COG4913 607 DNRAKLAALEAEL-------AELEEELAEAEER------LEALEAELDALQERREALQRLAEYSWdEIDVAsaereIAEL 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1541 QEVLRLADANNK--KTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWSLIETKVTAIEEKGK-----LLDT 1613
Cdd:COG4913 674 EAELERLDASSDdlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlelraLLEE 753
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1614 VVRS---KQHLYDTIKSLHELVTEAEKLkpMAAEVKALSGPVLAYLAAFTEAPAHaleeklnkLQNSVESLIDTLQTKSK 1690
Cdd:COG4913 754 RFAAalgDAVERELRENLEERIDALRAR--LNRAEEELERAMRAFNREWPAETAD--------LDADLESLPEYLALLDR 823
|
250 260 270
....*....|....*....|....*....|....*....
gi 373194212 1691 KADEDLETFE---------STEREIDQLRKRLNEARERA 1720
Cdd:COG4913 824 LEEDGLPEYEerfkellneNSIEFVADLLSKLRRAIREI 862
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1656-1857 |
1.62e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1656 LAAFTEAPAHAlEEKLNKLQNSVESL---IDTLQTKSKKADEDLetfESTEREIDQLRKRLNEARERAsnlyifgpdqDA 1732
Cdd:COG3883 4 LALAAPTPAFA-DPQIQAKQKELSELqaeLEAAQAELDALQAEL---EELNEEYNELQAELEALQAEI----------DK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1733 TEEELDELRWAVEQLLEsgkKFSGSTKARYQASQQLV----------PSDLAQHLTALELCAEATAQAMEEKQREQKRAR 1802
Cdd:COG3883 70 LQAEIAEAEAEIEERRE---ELGERARALYRSGGSVSyldvllgsesFSDFLDRLSALSKIADADADLLEELKADKAELE 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 373194212 1803 TVRSDYLTDLDEVQAWIRQAELKVQDrsiepvpLKDQLRQVQEELGTITDKLERL 1857
Cdd:COG3883 147 AKKAELEAKLAELEALKAELEAAKAE-------LEAQQAEQEALLAQLSAEEAAA 194
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1777-2060 |
1.64e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1777 LTALELCAEATAQAMEEKQREQKrartvrsdyltdLDEVQAWIRQAELKVQDrsiepvpLKDQLRQVQEELGTITDKLER 1856
Cdd:COG4942 6 LLALLLALAAAAQADAAAEAEAE------------LEQLQQEIAELEKELAA-------LKKEEKALLKQLAALERRIAA 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1857 LTRNGRTIaENTRDDTEKQLIDstvhnVTEQLNQVRNWLDERKQVVADTIDAWQRfLSLYEAVrtwteekrQFLVEPLKL 1936
Cdd:COG4942 67 LARRIRAL-EQELAALEAELAE-----LEKEIAELRAELEAQKEELAELLRALYR-LGRQPPL--------ALLLSPEDF 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1937 STLVQARQRLheystavkscKQINKNLSDMGKELEsigqvcsvgdlpEKLLEAEEAKVQVEGQLLERNALLQETSEEWEQ 2016
Cdd:COG4942 132 LDAVRRLQYL----------KYLAPARREQAEELR------------ADLAELAALRAELEAERAELEALLAELEEERAA 189
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 373194212 2017 CERKMKEVKTWIEKAKQSLESPQNKKKPLRDQHSIREKMLSDIA 2060
Cdd:COG4942 190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
685-1413 |
2.08e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 685 KLNEVKTLSDQVMDSVSNLDSQQ--IEEQIKSVER--RYADIGKKLQRKAQVLDMTA--QGIEATRQEIEENRDwiQQKK 758
Cdd:TIGR02168 180 KLERTRENLDRLEDILNELERQLksLERQAEKAERykELKAELRELELALLVLRLEElrEELEELQEELKEAEE--ELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 759 KQAQMSEpvgfdskqAEERLLALKAMLKEAEGKQMVIDTLEKRVGNMQNELESNEQQQLENEtKALRGEQSQLCTILTEG 838
Cdd:TIGR02168 258 LTAELQE--------LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL-ANLERQLEELEAQLEEL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 839 ISSATVAADARRKFEADLERARSWIKSKSNNLKKLSGYLPLKASKVEQDIVQHGELETDIDSFS-------------EKD 905
Cdd:TIGR02168 329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLElqiaslnneierlEAR 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 906 LNDILKQGNNLLKECSEEDRARLNKILDELNKDYEELKSEAQEKQAALADLLQGRKAFESEIDKCQRWINEAEV-ATSSD 984
Cdd:TIGR02168 409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEReLAQLQ 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 985 VRTSSIDILREQLAKYDR----LKKEANEYADDIEKLMQQ---------------GKSILPTVTD---ADKLELNEQLQN 1042
Cdd:TIGR02168 489 ARLDSLERLQENLEGFSEgvkaLLKNQSGLSGILGVLSELisvdegyeaaieaalGGRLQAVVVEnlnAAKKAIAFLKQN 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1043 mkeAHGRVAGIINERALALQKNIDEAEeSLARVAEAIQYMTDVQKELHELNKPIGSR------VEDVEA------MLDAY 1110
Cdd:TIGR02168 569 ---ELGRVTFLPLDSIKGTEIQGNDRE-ILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDNalelakKLRPG 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1111 ERIL---NDL---------KANKAKLSDL-QSINVADLHGVLTQQDDLMKAIESQIAKLRQLLLLRQQFI----ALITEI 1173
Cdd:TIGR02168 645 YRIVtldGDLvrpggvitgGSAKTNSSILeRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELeqlrKELEEL 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1174 TTFIAKYTEIVRDIENSGQTTEEKIKRYDDAILKIQECEATLASATDKGQQIAAEGStvdrnnitEQLQSLKQQLQGLRR 1253
Cdd:TIGR02168 725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE--------AEIEELEAQIEQLKE 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1254 AVETQREQHELAAAEHKRLANELAEILDWLEDKEKEVKS-----RPLLER------DPISVEAELQKHNELCDAVNEHLD 1322
Cdd:TIGR02168 797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAAterrlEDLEEQieelseDIESLAAEIEELEELIEELESELE 876
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1323 RIRNLKNsvpheegmpgSLKEMLSEAVSLLTSLpreMEERGNYLESNMKLRQEYAALTEKLrswvreAEIRLESDKDGLD 1402
Cdd:TIGR02168 877 ALLNERA----------SLEEALALLRSELEEL---SEELRELESKRSELRRELEELREKL------AQLELRLEGLEVR 937
|
810
....*....|.
gi 373194212 1403 FENILSDLEEH 1413
Cdd:TIGR02168 938 IDNLQERLSEE 948
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
3916-4132 |
2.21e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 45.93 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3916 ENEGKAEKGEMMVKKEVNVFEKIESERFKDSRELVVENEDKSVKEKQETNktVEELLftvgkGEDVKNAVEELLEAERQA 3995
Cdd:PTZ00341 929 KNQNENVPEHLKEHAEANIEEDAEENVEEDAEENVEENVEENVEENVEEN--VEENV-----EENVEENVEENVEENVEE 1001
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3996 MVVEQKIVDIEKGETVPVKLEDSKFKLEEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKVIEKGVEvpvd 4075
Cdd:PTZ00341 1002 NIEENVEENVEENIEENVEEYDEENVEEVEENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIEENIE---- 1077
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 373194212 4076 iKSVTKEIEGKItlpEEKVAEFEKSIEVPIKINDTklETEEIKLEDKVDSEKQERIE 4132
Cdd:PTZ00341 1078 -ENIEENVEENV---EENVEEIEENVEENVEENAE--ENAEENAEENAEEYDDENPE 1128
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1260-1932 |
2.46e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1260 EQHELAAAEHKRLANELAEILDWLEDKEKEVKSRPLLERDPI-SVEAELQKHNELCdaVNEHLDRIRNLKNSvpHEEGMP 1338
Cdd:pfam15921 206 EHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLeALKSESQNKIELL--LQQHQDRIEQLISE--HEVEIT 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1339 GsLKEMLSEAVSLLTSLPREME--ERGNYLESNMKLRQ--EYAALTEKLRSWVREAEiRLESDKdgldfenilsdleehk 1414
Cdd:pfam15921 282 G-LTEKASSARSQANSIQSQLEiiQEQARNQNSMYMRQlsDLESTVSQLRSELREAK-RMYEDK---------------- 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1415 iyfssepsIRELVSQQIqqagdkiwpsLNTSEQEELSAEQQQHTQLLKNTLNTAKSQRARLEQgaetwRDYTQTLERVRA 1494
Cdd:pfam15921 344 --------IEELEKQLV----------LANSELTEARTERDQFSQESGNLDDQLQKLLADLHK-----REKELSLEKEQN 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1495 VIARSRFTDEPVTtlaglqfniqkithalndIQNQQFELDlliERSQEVLRLadannKKTIEAQISEISAEWKELVSGLE 1574
Cdd:pfam15921 401 KRLWDRDTGNSIT------------------IDHLRRELD---DRNMEVQRL-----EALLKAMKSECQGQMERQMAAIQ 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1575 GRRDALEALSKHWEDLEAQWSLIETKVTAIEEKGKLLDTvvrSKQHLYDTIKSLHElvtEAEKLKPMAAEVKALSGPVLA 1654
Cdd:pfam15921 455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES---SERTVSDLTASLQE---KERAIEATNAEITKLRSRVDL 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1655 YLAAFTEAPAHalEEKLNKLQNSVESLIDTLQTKSKkadedleTFESTEREIDQLRKRLNEARERASNLYIfgpDQDATE 1734
Cdd:pfam15921 529 KLQELQHLKNE--GDHLRNVQTECEALKLQMAEKDK-------VIEILRQQIENMTQLVGQHGRTAGAMQV---EKAQLE 596
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1735 EELDELRWAVEQLlesgKKFSGSTKARYQasqqlvpsDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDlde 1814
Cdd:pfam15921 597 KEINDRRLELQEF----KILKDKKDAKIR--------ELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNE--- 661
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1815 vqawIRQAELKVQDRSIEPVPLKDQLRQVQEELGTITDKLERLTRNGRTIAENTRdDTEKQLIDSTVHNVTEQLNQVRNW 1894
Cdd:pfam15921 662 ----VKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR-NTLKSMEGSDGHAMKVAMGMQKQI 736
|
650 660 670
....*....|....*....|....*....|....*...
gi 373194212 1895 LDERKQvvadtIDAWQRFLSLYEAVRTWTEEKRQFLVE 1932
Cdd:pfam15921 737 TAKRGQ-----IDALQSKIQFLEEAMTNANKEKHFLKE 769
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
212-302 |
2.47e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 212 LKRWLEEMENSMQDlPDTKGEFGDMKTMLERYKHIQEEVRGKKTELDHLMDEASELSKLAKKNTPL--ERTKELLKRWEN 289
Cdd:smart00150 10 LEAWLEEKEQLLAS-EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEieERLEELNERWEE 88
|
90
....*....|...
gi 373194212 290 LSENVDERKRLIE 302
Cdd:smart00150 89 LKELAEERRQKLE 101
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
8312-8475 |
2.57e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 45.42 E-value: 2.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8312 TEVASIEAQTSPTAPFMEIETQTAEKVVVAVEQQTTPPPIEEKILTGIAVQTVTPEVPKTTETEAQTskpTTPEITTLDF 8391
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVET---THPEVIAAPV 924
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8392 NVQADLIEQPVVDVVET---QTTPEESPRQAETHETESQTIQPEPTQEIMIQTCPVTFAPEKVEVcELSSQTSMEEVKES 8468
Cdd:PRK10811 925 TEQPQVITESDVAVAQEvaeHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAA-EVETVTAVEPEVAP 1003
|
....*..
gi 373194212 8469 IDEQSQT 8475
Cdd:PRK10811 1004 AQVPEAT 1010
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
2951-3406 |
2.64e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 45.81 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2951 SMDDEIDKALKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKED---IEKKG---VKPGEKKKQNKSKMEKIRDE-SE 3023
Cdd:TIGR01612 1122 NLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDpeeIEKKIeniVTKIDKKKNIYDEIKKLLNEiAE 1201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3024 IAMNQANAkEQMKSKNDT--------------KESKEEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIKIDSSSEMRK 3089
Cdd:TIGR01612 1202 IEKDKTSL-EEVKGINLSygknlgklflekidEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFN 1280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3090 IETKEEK-----AQKDSANLSKKKQKGKEQTGTVKDKSNKDSVKSTKTENESEQMKKAIFIEdkteiQKEKDIKPVENIG 3164
Cdd:TIGR01612 1281 ISHDDDKdhhiiSKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDIN-----LYLNEIANIYNIL 1355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3165 NLDQLQK-----QEDTKsvKLMKSEKISETKVESKEKEPAKPKEQDKSKKNKKQKQGTENEVSKDQTPKKQSQQKEEKKT 3239
Cdd:TIGR01612 1356 KLNKIKKiidevKEYTK--EIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILS 1433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3240 EQS------KQKKSVEKSEVIDIKLEENEKIKIEIDVKAPKDE---------KEKKITGKEKEKKSESKDRKKKDIKPEV 3304
Cdd:TIGR01612 1434 EESnidtyfKNADENNENVLLLFKNIEMADNKSQHILKIKKDNatndhdfniNELKEHIDKSKGCKDEADKNAKAIEKNK 1513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3305 ALKEKAKEEQKAIINplinaiesdkKIEEKEIDNKDSKESSTPKKEMKKAGEAEKQIktkggkksKKEADINQKPATEiI 3384
Cdd:TIGR01612 1514 ELFEQYKKDVTELLN----------KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKF--------ILEAEKSEQKIKE-I 1574
|
490 500
....*....|....*....|..
gi 373194212 3385 KKEETIIVDKQIIEEKIDEKII 3406
Cdd:TIGR01612 1575 KKEKFRIEDDAAKNDKSNKAAI 1596
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
605-987 |
2.81e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 605 QDIEEGLNKLEAELTDAIAGKQAAQDLIQKYRTQVQNMQSWLDTLSKKVDViekgngQTIGQKIASVKEittefesqgpg 684
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV------ASAEREIAELEA----------- 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 685 klnEVKTLSDqvmdsvSNLDSQQIEEQIKSVERRYADIGKKLQRkaqvldmTAQGIEATRQEIEENRDWIQQKKKQAQms 764
Cdd:COG4913 676 ---ELERLDA------SSDDLAALEEQLEELEAELEELEEELDE-------LKGEIGRLEKELEQAEEELDELQDRLE-- 737
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 765 epvGFDSKQAEERLLALKAMLKEAEGkqmviDTLEKRVG-NMQNELESnEQQQLENETKALRGEQSQLCTILTEGISSAT 843
Cdd:COG4913 738 ---AAEDLARLELRALLEERFAAALG-----DAVERELReNLEERIDA-LRARLNRAEEELERAMRAFNREWPAETADLD 808
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 844 VAADARRKFEADLERARswikskSNNL----KKLSGYLplkASKVEQDIVQ-HGELETDIDSFSE--KDLNDILKQ---- 912
Cdd:COG4913 809 ADLESLPEYLALLDRLE------EDGLpeyeERFKELL---NENSIEFVADlLSKLRRAIREIKEriDPLNDSLKRipfg 879
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 913 -GNNL---LKECSEEDRARLNKILDELNKDYEELKSEAQEKQ-AALADLLQGRKAFESEIDKcqRWINEAevatsSDVRT 987
Cdd:COG4913 880 pGRYLrleARPRPDPEVREFRQELRAVTSGASLFDEELSEARfAALKRLIERLRSEEEESDR--RWRARV-----LDVRN 952
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
904-1154 |
2.86e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 904 KDLNDILKQgnNLLKECSEEDRAR-LNKILDELNKDYEELKsEAQEKQAALADLLQGRKAFESEIDKCQrwINEAEVATs 982
Cdd:COG4913 207 GDLDDFVRE--YMLEEPDTFEAADaLVEHFDDLERAHEALE-DAREQIELLEPIRELAERYAAARERLA--ELEYLRAA- 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 983 sdvrtssIDILREQLaKYDRLKKEANEYADDIEKLMQQgKSILptvtDADKLELNEQLQNMKEAHGRVAGiinERALALQ 1062
Cdd:COG4913 281 -------LRLWFAQR-RLELLEAELEELRAELARLEAE-LERL----EARLDALREELDELEAQIRGNGG---DRLEQLE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1063 KNIDEAEESLARVAEAIQymtDVQKELHELNKPIGSRVEDVEAMLDAYERILNDLKANKAKLSDLQSINVADLHGVLTQQ 1142
Cdd:COG4913 345 REIERLERELEERERRRA---RLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL 421
|
250
....*....|..
gi 373194212 1143 DDLmkaiESQIA 1154
Cdd:COG4913 422 REL----EAEIA 429
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2801-3104 |
3.11e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.11 E-value: 3.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2801 RQTRESSVSKQESNWDITKKRETRKTHQEAPKTKIPE-KRARRGSEYSKEKLQKEKIKINMEQQKQvfetkDEIVVEdTS 2879
Cdd:pfam17380 302 RQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEqERMAMERERELERIRQEERKRELERIRQ-----EEIAME-IS 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2880 KINvknnevEIKKEKVEDVQPEKRV--DVEKTKKIEAQKQDEKQEIQEEKHDVQQRSRSQEKKrkgkkkkpeksmddeid 2957
Cdd:pfam17380 376 RMR------ELERLQMERQQKNERVrqELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEA----------------- 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2958 kalKEIEDMDKQKKRDKSREQTKIKDTTQTVQTEKYKEDiekkgvkpGEKKKQNKSKMEKIRDESEIAMNQANA---KEQ 3034
Cdd:pfam17380 433 ---RQREVRRLEEERAREMERVRLEEQERQQQVERLRQQ--------EEERKRKKLELEKEKRDRKRAEEQRRKileKEL 501
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3035 MKSKNDTKESKEEKNIEKRNAKDEAKISKEKVESRKNESEKRSEIKIDsssEMRKIETKEEKAQKDSANL 3104
Cdd:pfam17380 502 EERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEME---ERRRIQEQMRKATEERSRL 568
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
4512-5279 |
3.17e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4512 EESESTNPEINKEIIQIYEEEKLPIELKELEEVIPTSVEESKLTDVEVKSPIKSEELEVKNEKVTLSSGEESKPIEVEIK 4591
Cdd:pfam02463 176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4592 KEIIEIYEGEKPTLKLEEDKKIINIEKDTMKVIEEVTTEIKSTDRILDQTAALIEDLTKELDMIKKEEEQNKIVTIVEER 4671
Cdd:pfam02463 256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4672 KKESEAEKKEQVSEKKSKTEKSKKEKQSKSEKSKDKKKEISIKEHEVIEEKDIVETEMTQIIEQLTEIKKEESKETPLLI 4751
Cdd:pfam02463 336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4752 KELEEKDTTETAELSQIMEQLTAEIKKkeieeisllpKESEVIEKKDIDIIETSELTRTMEELITAIKEISTDEIIDQTE 4831
Cdd:pfam02463 416 QLEDLLKEEKKEELEILEEEEESIELK----------QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4832 EKKMEKNITEELLTTSQSKTEEEVKpamessKIERVGKETKSEKNKKKQKKQNEKKEETPVLENPIMTEQENIKKIVEKS 4911
Cdd:pfam02463 486 LELLLSRQKLEERSQKESKARSGLK------VLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4912 VSEKKKTSKESKKKEVKEASKEEKIITEEPVKSYPLEKDINIVT--------EITETEKLVNGKAIEIIDLDAIQSSTNQ 4983
Cdd:pfam02463 560 VEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILnlaqldkaTLEADEDDKRAKVVEGILKDTELTKLKE 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4984 QSSKEGKTKPVEKSKKEETKTKSGKQKQFKEKPDIKPKSTSDKELKKQDKQENSSPDSKKKREGKSKKTNDIPTPVSQEI 5063
Cdd:pfam02463 640 SAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5064 VNEISSEEFKKEENQIEIKQASQEEIQPSVCTKSWASIVSM-KGNTETNNSTDISKVIPEESISETLKLEKIEKVEEIVP 5142
Cdd:pfam02463 720 EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEeKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5143 EELQNSPAHQKRMKHQKKKDAKQEKNVTEIKVSSTNTENEGEKEITIEESQELITKDSNKSYAQVAASNKRTSPQFNQED 5222
Cdd:pfam02463 800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 5223 IIIAKPTPIMLNE---NTEKKEIAQEEALIITEIENVKEETIKSEKEVTMDKKFDELVIE 5279
Cdd:pfam02463 880 EEQKLKDELESKEekeKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1555-1747 |
3.17e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.03 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1555 IEAQISEI-SAEWKELVSGLEGRRDALEALSKHWEdleaqwsliETKVTAIEEKGKLLDTVVRSKQH------LYDTIKS 1627
Cdd:PRK02224 192 LKAQIEEKeEKDLHERLNGLESELAELDEEIERYE---------EQREQARETRDEADEVLEEHEERreeletLEAEIED 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1628 LHELVTEAEKLKPMAAEVKALSGPVLAYL----------AAFTEAPAHALEEKLNKLQNSVESLIDTLQTKSKKADEDLE 1697
Cdd:PRK02224 263 LRETIAETEREREELAEEVRDLRERLEELeeerddllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNE 342
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 373194212 1698 TFESTEREIDQLRKRLNEARERASNLyifGPDQDATEEELDELRWAVEQL 1747
Cdd:PRK02224 343 EAESLREDADDLEERAEELREEAAEL---ESELEEAREAVEDRREEIEEL 389
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1196-1857 |
3.41e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 3.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1196 EKIKRYDDAILKIQECEATLASATDKGQQIAAEGSTVDRNNITEQLQSLKQQLQGLRRAVETQREQHELAAAEHKRLANE 1275
Cdd:COG1196 210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1276 LAEILDWLEDKEKEvksrpllerdpISVEAELQKHNElcdavnEHLDRirnlknsvpheegmpgsLKEMLSEAVSLLTSL 1355
Cdd:COG1196 290 EYELLAELARLEQD-----------IARLEERRRELE------ERLEE-----------------LEEELAELEEELEEL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1356 PREMEErgnylesnmkLRQEYAALTEKLrswvREAEIRLEsdkdglDFENILSDLEEhkiyfSSEPSIRELVSQQIQQAg 1435
Cdd:COG1196 336 EEELEE----------LEEELEEAEEEL----EEAEAELA------EAEEALLEAEA-----ELAEAEEELEELAEELL- 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1436 dkiwpslntsEQEELSAEQQQHTQLLKNTLNTAKSQRARLEQGAETWRDYTQTLERVRAVIARSRftdepvttlaglqfn 1515
Cdd:COG1196 390 ----------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL--------------- 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1516 iQKITHALNDIQNQQFELDLLIERSQEVLRLADANNKKTIEAQISEISAEW--KELVSGLEGRRDALEALskhweDLEAQ 1593
Cdd:COG1196 445 -EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllLEAEADYEGFLEGVKAA-----LLLAG 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1594 WSLIETKVTAIEEKGKLLDTVVRSkqhlYDTIKSLHELVTEAEKLKPMAAEVKALSGPVLAYLAAFTEAPAHALEEKLNK 1673
Cdd:COG1196 519 LRGLAGAVAVLIGVEAAYEAALEA----ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1674 LQnsVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASnlyifgpdqdATEEELDELRWAVEQLLESGKK 1753
Cdd:COG1196 595 GA--IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV----------TLAGRLREVTLEGEGGSAGGSL 662
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1754 FSGSTKARYQASQQLVP-------------SDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLDEVQAWIR 1820
Cdd:COG1196 663 TGGSRRELLAALLEAEAeleelaerlaeeeLELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742
|
650 660 670
....*....|....*....|....*....|....*..
gi 373194212 1821 QAELKVQDRSIEPVPLKDQLRQVQEELGTITDKLERL 1857
Cdd:COG1196 743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
963-1062 |
3.57e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 40.78 E-value: 3.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 963 FESEIDKCQRWINEAEVATSSDVRTSSIDILREQLAKYDRLKKEANEYADDIEKLMQQGKSILpTVTDADKLELNEQLQN 1042
Cdd:smart00150 3 FLRDADELEAWLEEKEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLI-EEGHPDAEEIEERLEE 81
|
90 100
....*....|....*....|
gi 373194212 1043 MKEAHGRVAGIINERALALQ 1062
Cdd:smart00150 82 LNERWEELKELAEERRQKLE 101
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2837-3121 |
3.59e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 3.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2837 EKRARRGSEYSKEKLQKEKIKINMEQQkqvFETKDEIVVEDTSKINVKNNEVEIKKEKVEDVqpekrvdvekTKKIEAQK 2916
Cdd:TIGR02169 219 EKREYEGYELLKEKEALERQKEAIERQ---LASLEEELEKLTEEISELEKRLEEIEQLLEEL----------NKKIKDLG 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2917 QDEKQEIQEEKHDVQ------QRSRSQEKKRKGKKKKPEKSMDDEIDKALKEIEDMDKQkKRDKSREQTKIKDTTQTVQT 2990
Cdd:TIGR02169 286 EEEQLRVKEKIGELEaeiaslERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE-IEEERKRRDKLTEEYAELKE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2991 E--KYKEDIEKKGVKPGEKKKQNKSKMEKIRDeseiamnqanAKEQMKSKNDTKESKEEKNIEKRNAKDEAKISKEKVES 3068
Cdd:TIGR02169 365 EleDLRAELEEVDKEFAETRDELKDYREKLEK----------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 373194212 3069 RKNESEKRSEIKIDsssEMRKIETKEEKAQKDSANLSKKKQKGKEQTGTVKDK 3121
Cdd:TIGR02169 435 KINELEEEKEDKAL---EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
705-1094 |
3.63e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 705 SQQIEEQIKSVERRYADIGKKLQRKAQVLDMTA---QGIEATRQEIEENRDWIQQKKKQAQMSEPvgfDSKQAEERLLAL 781
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELReelEKLEKEVKELEELKEEIEELEKELESLEG---SKRKLEEKIREL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 782 KAMLKEAEGKqmvIDTLEKRVGnmqnelESNEQQQLENETKALRGEQSQLctiltegissatvaADARRKFEADLERARS 861
Cdd:PRK03918 265 EERIEELKKE---IEELEEKVK------ELKELKEKAEEYIKLSEFYEEY--------------LDELREIEKRLSRLEE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 862 WIKSKSNNLKKLSGylplKASKVEQDIVQHGELETDIDSFSEK-----DLNDILKQGNNLLKECSEEDRARLNKILDELN 936
Cdd:PRK03918 322 EINGIEERIKELEE----KEERLEELKKKLKELEKRLEELEERhelyeEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 937 KDYEELKSEAQEKQAALADLLQGRKAFESEIDK----------CQRWINEAEVATSSDVRTSSIDILREQLAKYDRLKKE 1006
Cdd:PRK03918 398 KAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1007 ANEYADDIEKLMQQGKSILPTVTDADKL-ELNEQLQNMK----EAHGRVAGIINERALALQKNIDEAEESLARVAEAIQY 1081
Cdd:PRK03918 478 LRKELRELEKVLKKESELIKLKELAEQLkELEEKLKKYNleelEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKK 557
|
410
....*....|...
gi 373194212 1082 MTDVQKELHELNK 1094
Cdd:PRK03918 558 LAELEKKLDELEE 570
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1252-1834 |
3.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1252 RRAVETQREQHEL------AAAEHKRLANELAEI---LDWLEDKEKEVKSRpLLERDPISVEAELQKHNELCDAVNEHLD 1322
Cdd:COG4913 241 HEALEDAREQIELlepireLAERYAAARERLAELeylRAALRLWFAQRRLE-LLEAELEELRAELARLEAELERLEARLD 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1323 RIRNLKNSVpheegmpgsLKEMLSEAVSLLTSLPREMEERGNYLESNMKLRQEYAAlteklrsWVREAEIRLESDKDglD 1402
Cdd:COG4913 320 ALREELDEL---------EAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA-------LLAALGLPLPASAE--E 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1403 FENILSDLEEHKiyfSSEPSIRELVSQQIQQAGDKIWPSlntseQEELSAEQQQHTQLLKNTLN-TAKSQRARLE----- 1476
Cdd:COG4913 382 FAALRAEAAALL---EALEEELEALEEALAEAEAALRDL-----RRELRELEAEIASLERRKSNiPARLLALRDAlaeal 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1477 -----------------QGAETWRD-------------------YTQ--------------TLERVRAVIARSRFTDEPV 1506
Cdd:COG4913 454 gldeaelpfvgelievrPEEERWRGaiervlggfaltllvppehYAAalrwvnrlhlrgrlVYERVRTGLPDPERPRLDP 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1507 TTLAG-LQFNIQKITHALNDIQNQQFelDLLIERSQEVLRladaNNKK--TIEAQIS------EI---SAEWKELVSG-- 1572
Cdd:COG4913 534 DSLAGkLDFKPHPFRAWLEAELGRRF--DYVCVDSPEELR----RHPRaiTRAGQVKgngtrhEKddrRRIRSRYVLGfd 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1573 ----LEGRRDALEALSKHWEDLEAQWSLIETKVTAIEEKGKLLDTVVRSKQHLYDtIKSLHELVTEAEklkpmaAEVKAL 1648
Cdd:COG4913 608 nrakLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELE------AELERL 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1649 --SGPVLAylaafteapahALEEKLNKLQNSVESLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLYIF 1726
Cdd:COG4913 681 daSSDDLA-----------ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1727 GPDQDATEEELDELRWAVEQLLESGKKfsGSTKARYQASQQLV----------PSDLAQHLTALE-------LCAEATAQ 1789
Cdd:COG4913 750 LLEERFAAALGDAVERELRENLEERID--ALRARLNRAEEELEramrafnrewPAETADLDADLEslpeylaLLDRLEED 827
|
650 660 670 680
....*....|....*....|....*....|....*....|....*
gi 373194212 1790 AMEEKQREQKRARTVRSDylTDLDEVQAWIRQAELKVQDRsIEPV 1834
Cdd:COG4913 828 GLPEYEERFKELLNENSI--EFVADLLSKLRRAIREIKER-IDPL 869
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1532-1846 |
4.10e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 4.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1532 ELDLLI-ERSQEVLRLADANNK---------KTIEAQISEISAEWKELVSGLEGRRDALEALSKHWEDLEAQWSLIETKV 1601
Cdd:TIGR02169 188 RLDLIIdEKRQQLERLRREREKaeryqallkEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1602 TAIEEKGKLLDTVVRSK-QHLYDTIKS-LHELVTEAEKLKPmAAEVKALSGPVLAYLAAFTEAPAHALEEKLNKLQNSVE 1679
Cdd:TIGR02169 268 EEIEQLLEELNKKIKDLgEEEQLRVKEkIGELEAEIASLER-SIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIE 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1680 SLIDTLQTKSKKADEDLETFESTEREIDQLRKRLNEARERASNLYIfgpDQDATEEELDELRWAVEQLLESGKKFSGstk 1759
Cdd:TIGR02169 347 EERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE---KLEKLKREINELKRELDRLQEELQRLSE--- 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1760 ARYQASQQLvpSDLAQHLTALELCAEATAQAMEEKQREQKRARTVRSDYLTDLDEVQAWIRQAELKVQDRSIEPVPLKDQ 1839
Cdd:TIGR02169 421 ELADLNAAI--AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
....*..
gi 373194212 1840 LRQVQEE 1846
Cdd:TIGR02169 499 ARASEER 505
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
2708-2894 |
4.66e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 44.70 E-value: 4.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2708 QPVEQPVQPISPATPSESTPMKTKIITE--------NKTFSYAQILSQGLAPKPSSAVSSYSPPTSVPsTTLVSKQVKER 2779
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSETPKTAVSEEatvqkdttSQPTKVEEVASEKNGAEQSSATPNDTTNAQQP-TVGAEKSAQEQ 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 2780 SYSPVNSTTSSVHETS--PPQEARQTRESSVSKQESNWDITK-----KRETRKTHQEAPKTKIPEKRARRGSEYSKE--K 2850
Cdd:NF033875 128 PVVSPETTNEPLGQPTevAPAENEANKSTSIPKEFETPDVDKavdeaKKDPNITVVEKPAEDLGNVSSKDLAAKEKEvdQ 207
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 373194212 2851 LQKEKIKiNMEQQKQVFETKDEIVVEDTSKINVKNNEVEIKKEK 2894
Cdd:NF033875 208 LQKEQAK-KIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEK 250
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
10095-10455 |
5.74e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 5.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10095 NQHNETLAKIMERHAAVRDRLAAWDRYKLDQSKLLYW---LKEIERERSQLRFRFIQIQRLDEILQRIESLLEKIPEGEA 10171
Cdd:COG4717 91 AELQEELEELEEELEELEAELEELREELEKLEKLLQLlplYQELEALEAELAELPERLEELEERLEELRELEEELEELEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10172 QLESLQRQQETLLVKCDEALAVTIH---RDHAASVQRINNLSSSLEMWRDHIPRIQKRYKEYEEKaKEINSSFTEIGQAF 10248
Cdd:COG4717 171 ELAELQEELEELLEQLSLATEEELQdlaEELEELQQRLAELEEELEEAQEELEELEEELEQLENE-LEAAALEERLKEAR 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10249 STAF-HSSPASLTRTKQQLESVHQMQNRLSSMSVDLESLGVMIQQLREDLSPTDIKSLNEQRALFRLQHEDLEHQAALL- 10326
Cdd:COG4717 250 LLLLiAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALg 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 10327 ------ICRLEERCGLYDRWRDRLARLLAWigETEIRIQDCDSPN---------EPEETLKKLECEIQSDIALKQRellw 10391
Cdd:COG4717 330 lppdlsPEELLELLDRIEELQELLREAEEL--EEELQLEELEQEIaallaeagvEDEEELRAALEQAEEYQELKEE---- 403
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 373194212 10392 IQNTGQDLVEVAEEEESERLQRSLDELNERWDRLVAMGKARASKLMDLMRTMSTLEKRINELRS 10455
Cdd:COG4717 404 LEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
187-434 |
6.14e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.27 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 187 DLNTVQAQLKSLLHRWDDH----SEAHGKLKRWLEEME---NSMQDLPDTKGEFGDMKTMLERYKHIQEEVRGKKTELDH 259
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHikalEEIKKKSENYIDEIKaqiNDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIYDE 1191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 260 LMDEASELSKLAKKNTPLERTKEL-LKRWENLS----ENVDERKRLIENEMQEYNAYHAALQETEKWLLQISFQLMAHNS 334
Cdd:TIGR01612 1192 IKKLLNEIAEIEKDKTSLEEVKGInLSYGKNLGklflEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMD 1271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 335 L-----------------YITNK--EQTVSQIQQHENLLVEIENYTSVLNDLKlkgnGQITRYVAVNSEIKTIIETQLQN 395
Cdd:TIGR01612 1272 IkaemetfnishdddkdhHIISKkhDENISDIREKSLKIIEDFSEESDINDIK----KELQKNLLDAQKHNSDINLYLNE 1347
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 373194212 396 VQESYNSL-LNTALQIKKRLAESLIKFQEYENTLESIMKN 434
Cdd:TIGR01612 1348 IANIYNILkLNKIKKIIDEVKEYTKEIEENNKNIKDELDK 1387
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
6283-6507 |
6.90e-03 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 44.06 E-value: 6.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6283 ELSKSIEEKEEIINKTKDIVEEKGEIIKPMIDKDKKQEESSFKK------------SKRKNKQAKKIKHEEAETEIKSAD 6350
Cdd:PRK00448 5 EKFKKLLDQINIPDDLQSEALESAEIEKVVVDKKSKKWEFHLKFpnilpiedfklfKEKLKQSFSHIADIKVTFSIEVEN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6351 EDLLSSKIEKNIEILSTGSSTPSPDT----PKDIFQIEEKILNVTIPEQKIEvidiltiDEIKKDEKEIKNTTEQKIIF- 6425
Cdd:PRK00448 85 ITFTEELLLDYWNEIIEKAKKNSPLFksllKKQKVEVEGNKLIIKVNNEIER-------DHLKKKHLPKLIKQYEKFGFg 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 6426 -------------EEEKTLSKTQEEIEEINLQKIEEIPSTSPIKKKVMKEDKSKN---------DDKEIHEIKSLTTEEK 6483
Cdd:PRK00448 158 ilkidfeiddskeELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDPKEgpvqigkkiDKEEITPMKEINEEER 237
|
250 260
....*....|....*....|....
gi 373194212 6484 IVhqtseVIEDTIipFEVEKpIET 6507
Cdd:PRK00448 238 RV-----VVEGYV--FKVEI-KEL 253
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
8324-8479 |
8.35e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.87 E-value: 8.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 8324 TAPFMEIETQTAEKVVVAVEQQTTPPPIEEKILTGIAVQTVTPEVPKTTETEAQTSKPTTPEITTLDfNVQADLIEQPVV 8403
Cdd:PRK10811 852 DVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPE-VIAAPVTEQPQV 930
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 373194212 8404 DVVETQTTPEESPRQAETHETESQTIQPEPTQEimiQTCPVTFAPEKVEVCELSSQTSMEEVkESIDEQSQTMTPE 8479
Cdd:PRK10811 931 ITESDVAVAQEVAEHAEPVVEPQDETADIEEAA---ETAEVVVAEPEVVAQPAAPVVAEVAA-EVETVTAVEPEVA 1002
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3456-4298 |
9.36e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.81 E-value: 9.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3456 EKKETQGETI-KLEEISDKIDNTKEKSIKEIKEEIVIEVKEEISAIQVEEKKEKDIMQ---------------TDKIEIQ 3519
Cdd:pfam02463 170 KKKEALKKLIeETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyldylklneeridllQELLRDE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3520 SAIEKIPEKIIVEGSMETFTETVEIAKETEKVKVSDTKEERETPLSEISKTEELEDQQPEQKSEMPSTLKNKKSNKSKEK 3599
Cdd:pfam02463 250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3600 hpIEKVTPLSIVQEPKPNTSKSQPSTPKSDKKKKKQESKDKDNIESPQAKQKTITEKPFNDAKSIEESIEIPDVASEKSI 3679
Cdd:pfam02463 330 --LKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3680 FKEKEISTTLQPEIIPIIESEKDQIIEIDESKSFSQDLIEKPSTEEVPSLSLTEEILNVTDTGSPIEKSSSTSSGKALII 3759
Cdd:pfam02463 408 QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3760 ERTVTTVTTTTSMPGSvevkppNVKSMKSVEILESIPLPKIVGSKPTELITLRPETVEASLTTRYARISDDSAVGIPSKE 3839
Cdd:pfam02463 488 LLLSRQKLEERSQKES------KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3840 FLDMLADESNFDYANYINLVEDDQPILFGSVQDRRKDRSGTPLSAKSVENAkdeREVDDLKEGQGVDAKISQDTLGENEG 3919
Cdd:pfam02463 562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKAT---LEADEDDKRAKVVEGILKDTELTKLK 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 3920 KAEKGEMMVKKEVNVFEKIESERFKDSRELVVEnEDKSVKEKQETNKTVEELLFTVGKGEDVKNAVEELLEAERQAMVVE 3999
Cdd:pfam02463 639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSEL-TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4000 QKIVDIEKGETVPVKLEDSKFKLEEIENKTILNEEKIRDLEKSIEVPVKIETEEVNNKTTIVEEKVIEKGVEVPVDIKSV 4079
Cdd:pfam02463 718 EAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4080 TKEIEGKITLPEEKVAEFEKSIEVPIKINDTKLETEEIKLEDKVDSEKQERIEIEDFKSIMKGIEDK----TDLIEEKLI 4155
Cdd:pfam02463 798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITkeelLQELLLKEE 877
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 4156 DTGKREDVSIKLKKIENKPTQDEEKIKEVPINIKDFESIIEKINSETILVEEKDLK-EKIEIPLEIKSITEEVEDKTALF 4234
Cdd:pfam02463 878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYeEEPEELLLEEADEKEKEENNKEE 957
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 373194212 4235 EEKVVESEKSFKEVPVKIDYSKSQEEIKVEEKIVEKQETIVNKDFKSKMENIEDKTILEENIIE 4298
Cdd:pfam02463 958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1503-1694 |
9.56e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 42.05 E-value: 9.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1503 DEPVTTLAGLQFNIQKITHALNDIQNQQFELDLLIERSQEVLRLADANnKKTIEAQISEISAEWKELVSGLEGRRDALEA 1582
Cdd:cd00176 26 TDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQERLEELNQRWEELRELAEERRQRLEE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 373194212 1583 LSKHWEDLEAQWSLIETkvtaIEEKGKLLDT--VVRSKQHLYDTIKSLHELVTEAEKLKPmaaEVKALSGPVLAYLAAFT 1660
Cdd:cd00176 105 ALDLQQFFRDADDLEQW----LEEKEAALASedLGKDLESVEELLKKHKELEEELEAHEP---RLKSLNELAEELLEEGH 177
|
170 180 190
....*....|....*....|....*....|....
gi 373194212 1661 EAPAHALEEKLNKLQNSVESLIDTLQTKSKKADE 1694
Cdd:cd00176 178 PDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| |
