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Conserved domains on  [gi|364808931|gb|AEW67619|]
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ATP synthase 6, partial (mitochondrion) [Cardellina versicolor]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009573)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-171 7.85e-83

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177181  Cd Length: 227  Bit Score: 243.58  E-value: 7.85e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00120 161 LTANLTAGHLL 171
 
Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-171 7.85e-83

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 243.58  E-value: 7.85e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00120 161 LTANLTAGHLL 171
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-171 5.91e-35

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 121.93  E-value: 5.91e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931    6 FDQFSSPSFLGIPLILISMTFPA-----LLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:TIGR01131   2 FSQFDISPITLFSLTLLSLILLLsllifLISSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170
                  ....*....|.
gi 364808931  161 LTANLTAGHLL 171
Cdd:TIGR01131 162 LFANISAGHLL 172
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-171 7.53e-24

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 91.31  E-value: 7.53e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310   25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104


                 ..
gi 364808931 170 LL 171
Cdd:cd00310  105 LL 106
ATP-synt_A pfam00119
ATP synthase A chain;
90-171 6.14e-17

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 74.45  E-value: 6.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSAS-LGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160


                  ...
gi 364808931  169 HLL 171
Cdd:pfam00119 161 HLL 163
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-171 1.25e-10

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 57.39  E-value: 1.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQ-PSASLGHLLPEGTPtPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:COG0356   78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKgLGGYLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156


                 ...
gi 364808931 169 HLL 171
Cdd:COG0356  157 HII 159
 
Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-171 7.85e-83

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 243.58  E-value: 7.85e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00120 161 LTANLTAGHLL 171
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-171 3.94e-81

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 239.39  E-value: 3.94e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00132 161 LTANLTAGHLL 171
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-171 3.41e-79

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 234.48  E-value: 3.41e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00073 161 LTANLTAGHLL 171
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-171 9.40e-62

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 190.16  E-value: 9.40e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00179 161 LTANITAGHLL 171
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-171 1.40e-60

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 187.47  E-value: 1.40e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPALLLPSlDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPT-PNRLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170
                 ....*....|.
gi 364808931 161 LTANLTAGHLL 171
Cdd:MTH00101 160 LTANITAGHLL 170
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-171 5.91e-35

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 121.93  E-value: 5.91e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931    6 FDQFSSPSFLGIPLILISMTFPA-----LLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFL 80
Cdd:TIGR01131   2 FSQFDISPITLFSLTLLSLILLLsllifLISSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   81 LLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170
                  ....*....|.
gi 364808931  161 LTANLTAGHLL 171
Cdd:TIGR01131 162 LFANISAGHLL 172
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 1-171 2.15e-33

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 117.77  E-value: 2.15e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLILISMTFPAL-LLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIF 79
Cdd:MTH00035   3 INNSIFGQFSPDTILFIPLTLLSSVIALSwLFFINPTNWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFIL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  80 LLLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGV 159
Cdd:MTH00035  83 ILSINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGL 162

                        170
                 ....*....|..
gi 364808931 160 RLTANLTAGHLL 171
Cdd:MTH00035 163 RLAANLTAGHLL 174
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-171 3.95e-30

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 109.10  E-value: 3.95e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLsfFDQFSSPSFLGIPLILISMTFPALLLPSLdnRW-ITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIF 79
Cdd:MTH00157   3 TNL--FSIFDPSTSFNLSLNWLSTFLGLLFIPSS--FWlIPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  80 LLLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170
                 ....*....|..
gi 364808931 160 RLTANLTAGHLL 171
Cdd:MTH00157 159 RLAANMIAGHLL 170
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 4-171 6.79e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 103.79  E-value: 6.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   4 SFFDQFSSPSFLGIPLILISMTFPALLLPSLdNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFLLLI 83
Cdd:MTH00173   7 SSFDDHNSSFSSLSFLMWLLSLMSLFFFSSS-VWVSSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  84 NLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTA 163
Cdd:MTH00173  86 NLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLA 165


                 ....*...
gi 364808931 164 NLTAGHLL 171
Cdd:MTH00173 166 NISAGHIV 173
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-171 6.73e-27

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 101.26  E-value: 6.73e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLIL---ISMTFPALLLPSLdNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLM 77
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISlswITLLLFLLLMPSS-VWFCPSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  78 IFLLLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLAL 157
Cdd:MTH00176  80 ILVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTL 159

                        170
                 ....*....|....
gi 364808931 158 GVRLTANLTAGHLL 171
Cdd:MTH00176 160 AVRLAANLSAGHLL 173
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-171 7.53e-24

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 91.31  E-value: 7.53e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310   25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104


                 ..
gi 364808931 170 LL 171
Cdd:cd00310  105 LL 106
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 4-170 8.63e-22

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 87.87  E-value: 8.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   4 SFFDQFSSPSFLGIPLILISMTFPALLLPSlDNRWIT-NRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMIFLLL 82
Cdd:MTH00005   8 SFDPATNSLFNNLSSTAFWAFNFSIILLLS-SSFWITpNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIIL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  83 INLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLT 162
Cdd:MTH00005  87 MNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLA 166


                 ....*...
gi 364808931 163 ANLTAGHL 170
Cdd:MTH00005 167 ANMSAGHI 174
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-171 3.27e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 80.86  E-value: 3.27e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGI--PLILISMTFPALLLPSLDNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGHKWALILTSLMI 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLtnSSIMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  79 FLLLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170
                 ....*....|...
gi 364808931 159 VRLTANLTAGHLL 171
Cdd:MTH00172 161 VRLAANLSAGHLL 173
ATP-synt_A pfam00119
ATP synthase A chain;
90-171 6.14e-17

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 74.45  E-value: 6.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSAS-LGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160


                  ...
gi 364808931  169 HLL 171
Cdd:pfam00119 161 HLL 163
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 1-171 7.86e-16

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 72.35  E-value: 7.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931   1 MNLSFFDQFSSPSFLGIPLI----LISMTFPALLLPSL---------DNRWITNRLSTLQLWFVNLVTKQLMMPLNKKGH 67
Cdd:MTH00175   1 MLAAYFDQFNIIRLITIQAFlgdwLVTFTNSSMMMVLAviifwlllkGDKLIPNRWQSIMELIYLNIRSVVHDNLGKSGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  68 KWALILTSLMIFLLLINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIET 147
Cdd:MTH00175  81 KYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLIET 160

                        170       180
                 ....*....|....*....|....
gi 364808931 148 TSLLIRPLALGVRLTANLTAGHLL 171
Cdd:MTH00175 161 LSYLIRAISLGVRLAANISAGHLL 184
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 90-171 7.34e-11

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 58.80  E-value: 7.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGH 169
Cdd:MTH00174 111 PYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGH 190


                 ..
gi 364808931 170 LL 171
Cdd:MTH00174 191 LL 192
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-171 1.25e-10

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 57.39  E-value: 1.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQ-PSASLGHLLPEGTPtPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:COG0356   78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKgLGGYLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156


                 ...
gi 364808931 169 HLL 171
Cdd:COG0356  157 HII 159
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 91-171 3.07e-09

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 54.03  E-value: 3.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  91 YTFTPTTQLSMNLALAFPLWLATLLTGLRNQpsaSLGHLLPEGTPTPlIPALILIETTSLLIRPLALGVRLTANLTAGHL 170
Cdd:PRK05815  95 LLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HPLLLPIEIISEFSRPISLSLRLFGNMLAGEL 170


                 .
gi 364808931 171 L 171
Cdd:PRK05815 171 I 171
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 90-171 1.28e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 46.12  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNqpSASLGHLLPEGTPTPLIP-ALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:MTH00087  72 PYSFSPCGMVEFTFLYALVAWLSTFLSFLSK--SEKFSVYLSKGSDSFLKTfSMLFVEIVSELSRPLALTLRLTVNLMVG 149


                 ...
gi 364808931 169 HLL 171
Cdd:MTH00087 150 HLI 152
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 90-171 1.56e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 43.96  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQP-SASLGHLlPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:PRK13419 191 PYGATATGNINVTLTLAVFTFFITQYAAIKAHGiKGYLAHL-TGGTHWSLWIIMIPIEFIGLFTKPFALTVRLFANMTAG 269


                 ...
gi 364808931 169 HLL 171
Cdd:PRK13419 270 HIV 272
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-171 3.80e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 42.57  E-value: 3.80e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 364808931  94 TPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIE-TTSLLIRPLALGVRLTANLTAGHLL 171
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEfIVSPMAKTFALTVRLLANMTAGHVI 295
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 90-168 2.84e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 36.40  E-value: 2.84e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 364808931  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSASLGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:MTH00050  43 PYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISYIIRPVVLILRPFINISLG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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