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Conserved domains on  [gi|364502422|dbj|BAL42198|]
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DET1, partial [Cardamine glauca]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Det1 super family cl12369
De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of ...
 2-105 2.43e-42

De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of approximately 550 amino acids. Det1 (de-etiolated-1) is an essential negative regulator of plant light responses, and it is a component of the Arabidopsis CDD complex containing DDB1 and COP10 ubiquitin E2 variant. Mammalian Det1 forms stable DDD-E2 complexes, consisting of DDB1, DDA1 (DET1, DDB1 Associated 1), and a member of the UBE2E group of canonical ubiquitin conjugating enzymes and modulates Cul4A function.


The actual alignment was detected with superfamily member pfam09737:

Pssm-ID: 462868  Cd Length: 412  Bit Score: 142.79  E-value: 2.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364502422    2 LLIKFGSVDGGVTRSAD--HHPAFFAVYNMETTDIVAFYQNSAEDLYQLFEQFSDHFTVSSSTPFMNFVTSHSNSVHALE 79
Cdd:pfam09737 206 LLIKYASEDVVTLRVTDpnSQPSFFVVYNMETTEVLAVYENTSEELLQLFEQFCDHFRNARLNSTGNFPSSPSNNIYARE 285

                          90       100       110
                  ....*....|....*....|....*....|.
gi 364502422   80 QLKYMK-----NKSNSFSQFVKKMLVSLPFS 105
Cdd:pfam09737 286 QLRRFKqtiinAKAGGFTEAVKRLLAQLPIS 316
 
Name Accession Description Interval E-value
Det1 pfam09737
De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of ...
 2-105 2.43e-42

De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of approximately 550 amino acids. Det1 (de-etiolated-1) is an essential negative regulator of plant light responses, and it is a component of the Arabidopsis CDD complex containing DDB1 and COP10 ubiquitin E2 variant. Mammalian Det1 forms stable DDD-E2 complexes, consisting of DDB1, DDA1 (DET1, DDB1 Associated 1), and a member of the UBE2E group of canonical ubiquitin conjugating enzymes and modulates Cul4A function.


Pssm-ID: 462868  Cd Length: 412  Bit Score: 142.79  E-value: 2.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364502422    2 LLIKFGSVDGGVTRSAD--HHPAFFAVYNMETTDIVAFYQNSAEDLYQLFEQFSDHFTVSSSTPFMNFVTSHSNSVHALE 79
Cdd:pfam09737 206 LLIKYASEDVVTLRVTDpnSQPSFFVVYNMETTEVLAVYENTSEELLQLFEQFCDHFRNARLNSTGNFPSSPSNNIYARE 285

                          90       100       110
                  ....*....|....*....|....*....|.
gi 364502422   80 QLKYMK-----NKSNSFSQFVKKMLVSLPFS 105
Cdd:pfam09737 286 QLRRFKqtiinAKAGGFTEAVKRLLAQLPIS 316
 
Name Accession Description Interval E-value
Det1 pfam09737
De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of ...
 2-105 2.43e-42

De-etiolated protein 1 Det1; This is the C-terminal conserved 400 residues of Det1 proteins of approximately 550 amino acids. Det1 (de-etiolated-1) is an essential negative regulator of plant light responses, and it is a component of the Arabidopsis CDD complex containing DDB1 and COP10 ubiquitin E2 variant. Mammalian Det1 forms stable DDD-E2 complexes, consisting of DDB1, DDA1 (DET1, DDB1 Associated 1), and a member of the UBE2E group of canonical ubiquitin conjugating enzymes and modulates Cul4A function.


Pssm-ID: 462868  Cd Length: 412  Bit Score: 142.79  E-value: 2.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 364502422    2 LLIKFGSVDGGVTRSAD--HHPAFFAVYNMETTDIVAFYQNSAEDLYQLFEQFSDHFTVSSSTPFMNFVTSHSNSVHALE 79
Cdd:pfam09737 206 LLIKYASEDVVTLRVTDpnSQPSFFVVYNMETTEVLAVYENTSEELLQLFEQFCDHFRNARLNSTGNFPSSPSNNIYARE 285

                          90       100       110
                  ....*....|....*....|....*....|.
gi 364502422   80 QLKYMK-----NKSNSFSQFVKKMLVSLPFS 105
Cdd:pfam09737 286 QLRRFKqtiinAKAGGFTEAVKRLLAQLPIS 316
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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