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Conserved domains on  [gi|363652704|gb|EHL91734|]
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hypothetical protein HMPREF1019_00001 [Campylobacter sp. 10_1_50]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3990 super family cl46330
Protein of unknown function (DUF3990); A family of uncharacterized proteins found by ...
 693-851 2.29e-22

Protein of unknown function (DUF3990); A family of uncharacterized proteins found by clustering human gut metagenomic sequences.


The actual alignment was detected with superfamily member pfam18760:

Pssm-ID: 480670  Cd Length: 136  Bit Score: 94.00  E-value: 2.29e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   693 NTDGTPKIFYHGTKKSnISEFDQKFDKS---KWGFFFTTDKGLSEEYSKGRYGLkepnsgVMEVYINAKKPFDLREEITK 769
Cdd:pfam18760    1 DENGEPLVVYHGTGAD-FDEFDREKSGSggdIWGFWFSDRKDDASDYASGGKGN------VYPVYLNIKNPLVVDDPILK 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   770 dtakkyqallgnlakrddiKNGVGKNLYeyiKNTNLKQYDTKARAFKDKlqnAGYDSIILD-----DNVIVAFNPNQIKH 844
Cdd:pfam18760   74 -------------------EAYGYGIIF---KRFGNGGFDTRERLEADM---EGYDGIIAEkeddgDTEVVVFEPNQIKS 128


                   ....*...
gi 363652704   845 V-KNNGNF 851
Cdd:pfam18760  129 AtGNNGTF 136
LPD23 pfam18838
Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually ...
 584-640 1.82e-20

Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually N-terminal to a metallopeptidase domain. The domain is found in both in polyvalent proteins of conjugative elements and phages/prophages.


:

Pssm-ID: 465885  Cd Length: 58  Bit Score: 85.78  E-value: 1.82e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 363652704   584 SFAGEKALNASANKLSKAKAMLEKGEDEVKIWQSTGWYKDKDGAWKFEIDDSPAKIK 640
Cdd:pfam18838    2 SFGGENAANADLEALARAKEMEAQGEDAETIWRETGWFRGADGKWRFEIDDSAATLR 58
 
Name Accession Description Interval E-value
ART-PolyVal pfam18760
ADP-Ribosyltransferase in polyvalent proteins; A family of ADP-Ribosyltransferases found in ...
 693-851 2.29e-22

ADP-Ribosyltransferase in polyvalent proteins; A family of ADP-Ribosyltransferases found in polyvalent proteins of phages and conjugative elements. These are in turn related to the Tox-ART-HYD2 group of ADP-Ribosyltransferases that are seen in polymorphic toxin systems and in toxin-antitoxin systems. These are predicted to modify host proteins.


Pssm-ID: 408531  Cd Length: 136  Bit Score: 94.00  E-value: 2.29e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   693 NTDGTPKIFYHGTKKSnISEFDQKFDKS---KWGFFFTTDKGLSEEYSKGRYGLkepnsgVMEVYINAKKPFDLREEITK 769
Cdd:pfam18760    1 DENGEPLVVYHGTGAD-FDEFDREKSGSggdIWGFWFSDRKDDASDYASGGKGN------VYPVYLNIKNPLVVDDPILK 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   770 dtakkyqallgnlakrddiKNGVGKNLYeyiKNTNLKQYDTKARAFKDKlqnAGYDSIILD-----DNVIVAFNPNQIKH 844
Cdd:pfam18760   74 -------------------EAYGYGIIF---KRFGNGGFDTRERLEADM---EGYDGIIAEkeddgDTEVVVFEPNQIKS 128


                   ....*...
gi 363652704   845 V-KNNGNF 851
Cdd:pfam18760  129 AtGNNGTF 136
LPD23 pfam18838
Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually ...
 584-640 1.82e-20

Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually N-terminal to a metallopeptidase domain. The domain is found in both in polyvalent proteins of conjugative elements and phages/prophages.


Pssm-ID: 465885  Cd Length: 58  Bit Score: 85.78  E-value: 1.82e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 363652704   584 SFAGEKALNASANKLSKAKAMLEKGEDEVKIWQSTGWYKDKDGAWKFEIDDSPAKIK 640
Cdd:pfam18838    2 SFGGENAANADLEALARAKEMEAQGEDAETIWRETGWFRGADGKWRFEIDDSAATLR 58
 
Name Accession Description Interval E-value
ART-PolyVal pfam18760
ADP-Ribosyltransferase in polyvalent proteins; A family of ADP-Ribosyltransferases found in ...
 693-851 2.29e-22

ADP-Ribosyltransferase in polyvalent proteins; A family of ADP-Ribosyltransferases found in polyvalent proteins of phages and conjugative elements. These are in turn related to the Tox-ART-HYD2 group of ADP-Ribosyltransferases that are seen in polymorphic toxin systems and in toxin-antitoxin systems. These are predicted to modify host proteins.


Pssm-ID: 408531  Cd Length: 136  Bit Score: 94.00  E-value: 2.29e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   693 NTDGTPKIFYHGTKKSnISEFDQKFDKS---KWGFFFTTDKGLSEEYSKGRYGLkepnsgVMEVYINAKKPFDLREEITK 769
Cdd:pfam18760    1 DENGEPLVVYHGTGAD-FDEFDREKSGSggdIWGFWFSDRKDDASDYASGGKGN------VYPVYLNIKNPLVVDDPILK 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363652704   770 dtakkyqallgnlakrddiKNGVGKNLYeyiKNTNLKQYDTKARAFKDKlqnAGYDSIILD-----DNVIVAFNPNQIKH 844
Cdd:pfam18760   74 -------------------EAYGYGIIF---KRFGNGGFDTRERLEADM---EGYDGIIAEkeddgDTEVVVFEPNQIKS 128


                   ....*...
gi 363652704   845 V-KNNGNF 851
Cdd:pfam18760  129 AtGNNGTF 136
LPD23 pfam18838
Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually ...
 584-640 1.82e-20

Large polyvalent protein associated domain 23; This is an alpha-helical domain that is usually N-terminal to a metallopeptidase domain. The domain is found in both in polyvalent proteins of conjugative elements and phages/prophages.


Pssm-ID: 465885  Cd Length: 58  Bit Score: 85.78  E-value: 1.82e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 363652704   584 SFAGEKALNASANKLSKAKAMLEKGEDEVKIWQSTGWYKDKDGAWKFEIDDSPAKIK 640
Cdd:pfam18838    2 SFGGENAANADLEALARAKEMEAQGEDAETIWRETGWFRGADGKWRFEIDDSAATLR 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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