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Conserved domains on  [gi|354998605|gb|AER49931|]
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DNA primase [Mycobacterium phage LHTSCC]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CHC2 super family cl21601
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 32-85 6.14e-17

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


The actual alignment was detected with superfamily member smart00400:

Pssm-ID: 451328 [Multi-domain]  Cd Length: 55  Bit Score: 69.24  E-value: 6.14e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 354998605    32 KCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEAERIAE 85
Cdd:smart00400   2 KGLCPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
 
Name Accession Description Interval E-value
ZnF_CHCC smart00400
zinc finger;
32-85 6.14e-17

zinc finger;


Pssm-ID: 128681 [Multi-domain]  Cd Length: 55  Bit Score: 69.24  E-value: 6.14e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 354998605    32 KCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEAERIAE 85
Cdd:smart00400   2 KGLCPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
zf-CHC2 pfam01807
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 24-87 2.38e-15

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


Pssm-ID: 426447 [Multi-domain]  Cd Length: 95  Bit Score: 66.50  E-value: 2.38e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 354998605   24 KDTGKDWIKClCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEAeriAEEL 87
Cdd:pfam01807  25 KKRGKDYVGL-CPFHHEKTPSFTVSPDKQFYHCFGCGAGGDVIKFLMKIEKLSFVEA---VEKL 84
dnaG TIGR01391
DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria ...
 24-103 3.02e-13

DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria protein. Most members of this family contain nearly two hundred additional residues C-terminal to the region represented here, but conservation between species is poor and the C-terminal region was not included in the seed alignment. This protein contains a CHC2 zinc finger (pfam01807) and a Toprim domain (pfam01751). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273595 [Multi-domain]  Cd Length: 415  Bit Score: 64.93  E-value: 3.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354998605   24 KDTGKDWiKCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEA-ERIAEE------LSPGSDRAVP 96
Cdd:TIGR01391  27 KKKGRNY-VGLCPFHHEKTPSFSVSPEKQFYHCFGCGAGGDAIKFLMEIEGISFVEAvEELAKRagidlpFEKDQQEKKE 105


                  ....*..
gi 354998605   97 TKSERQS 103
Cdd:TIGR01391 106 QKSKRKK 112
DnaG COG0358
DNA primase (bacterial type) [Replication, recombination and repair];
27-103 6.66e-12

DNA primase (bacterial type) [Replication, recombination and repair];


Pssm-ID: 440127 [Multi-domain]  Cd Length: 465  Bit Score: 61.31  E-value: 6.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354998605  27 GKDWiKCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEA-ERIAEEL------SPGSDRAVPTKS 99
Cdd:COG0358   30 GRNY-KGLCPFHDEKTPSFTVSPEKQFYHCFGCGAGGDVISFLMEYEGLSFPEAvEELAERAgielpeEEGSPEEREEAS 108


                 ....
gi 354998605 100 ERQS 103
Cdd:COG0358  109 ERER 112
 
Name Accession Description Interval E-value
ZnF_CHCC smart00400
zinc finger;
32-85 6.14e-17

zinc finger;


Pssm-ID: 128681 [Multi-domain]  Cd Length: 55  Bit Score: 69.24  E-value: 6.14e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 354998605    32 KCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEAERIAE 85
Cdd:smart00400   2 KGLCPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
zf-CHC2 pfam01807
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 24-87 2.38e-15

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


Pssm-ID: 426447 [Multi-domain]  Cd Length: 95  Bit Score: 66.50  E-value: 2.38e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 354998605   24 KDTGKDWIKClCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEAeriAEEL 87
Cdd:pfam01807  25 KKRGKDYVGL-CPFHHEKTPSFTVSPDKQFYHCFGCGAGGDVIKFLMKIEKLSFVEA---VEKL 84
dnaG TIGR01391
DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria ...
 24-103 3.02e-13

DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria protein. Most members of this family contain nearly two hundred additional residues C-terminal to the region represented here, but conservation between species is poor and the C-terminal region was not included in the seed alignment. This protein contains a CHC2 zinc finger (pfam01807) and a Toprim domain (pfam01751). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273595 [Multi-domain]  Cd Length: 415  Bit Score: 64.93  E-value: 3.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354998605   24 KDTGKDWiKCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEA-ERIAEE------LSPGSDRAVP 96
Cdd:TIGR01391  27 KKKGRNY-VGLCPFHHEKTPSFSVSPEKQFYHCFGCGAGGDAIKFLMEIEGISFVEAvEELAKRagidlpFEKDQQEKKE 105


                  ....*..
gi 354998605   97 TKSERQS 103
Cdd:TIGR01391 106 QKSKRKK 112
DnaG COG0358
DNA primase (bacterial type) [Replication, recombination and repair];
27-103 6.66e-12

DNA primase (bacterial type) [Replication, recombination and repair];


Pssm-ID: 440127 [Multi-domain]  Cd Length: 465  Bit Score: 61.31  E-value: 6.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354998605  27 GKDWiKCLCPFHAEEVPSAAVSFVRQAFNCLACGVKGDVLGLIKKQEEVSYAEA-ERIAEEL------SPGSDRAVPTKS 99
Cdd:COG0358   30 GRNY-KGLCPFHDEKTPSFTVSPEKQFYHCFGCGAGGDVISFLMEYEGLSFPEAvEELAERAgielpeEEGSPEEREEAS 108


                 ....
gi 354998605 100 ERQS 103
Cdd:COG0358  109 ERER 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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