NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|354543708|emb|CCE40430|]
View 

hypothetical protein CPAR2_104660 [Candida parapsilosis]

Protein Classification

KilA-N domain-containing protein( domain architecture ID 10516234)

KilA-N domain-containing protein is a DNA-binding protein such as Saccharomyces cerevisiae transcription factor PHD1 that functions in pseudohyphal growth

CATH:  3.10.260.10
Gene Ontology:  GO:0003677|GO:0005634
PubMed:  11897024
SCOP:  3000771

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 405-496 2.01e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


:

Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.02  E-value: 2.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354543708  405 QVRINKILVsRREDNNYINCTKLLNVtKMTRGKR-DGILKTEKVKDVVKVGTM------------------NLKGVWIPF 465
Cdd:pfam04383   2 QYNDFEIII-RRDKDGYINATKLCKA-AGEKTKRfRNWLRLESTKELIEELEEennipkiitiigrkgkggRLQGTYVHP 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 354543708  466 DRAYEIARNegIDELLHpLFVRNIKEYFLTG 496
Cdd:pfam04383  80 DLALAIASW--ISPEFA-LKVSKIIDEYKSG 107
 
Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 405-496 2.01e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.02  E-value: 2.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354543708  405 QVRINKILVsRREDNNYINCTKLLNVtKMTRGKR-DGILKTEKVKDVVKVGTM------------------NLKGVWIPF 465
Cdd:pfam04383   2 QYNDFEIII-RRDKDGYINATKLCKA-AGEKTKRfRNWLRLESTKELIEELEEennipkiitiigrkgkggRLQGTYVHP 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 354543708  466 DRAYEIARNegIDELLHpLFVRNIKEYFLTG 496
Cdd:pfam04383  80 DLALAIASW--ISPEFA-LKVSKIIDEYKSG 107
 
Name Accession Description Interval E-value
KilA-N pfam04383
KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved ...
 405-496 2.01e-09

KilA-N domain; The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.


Pssm-ID: 367917  Cd Length: 107  Bit Score: 55.02  E-value: 2.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354543708  405 QVRINKILVsRREDNNYINCTKLLNVtKMTRGKR-DGILKTEKVKDVVKVGTM------------------NLKGVWIPF 465
Cdd:pfam04383   2 QYNDFEIII-RRDKDGYINATKLCKA-AGEKTKRfRNWLRLESTKELIEELEEennipkiitiigrkgkggRLQGTYVHP 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 354543708  466 DRAYEIARNegIDELLHpLFVRNIKEYFLTG 496
Cdd:pfam04383  80 DLALAIASW--ISPEFA-LKVSKIIDEYKSG 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH