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Conserved domains on  [gi|352963797|gb|AEQ63928|]
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ribosomal protein L32, partial [Drosophila repleta]

Protein Classification

eL32 family ribosomal protein( domain architecture ID 10483324)

eL32 family ribosomal protein similar to eukaryotic 60S ribosomal protein L32

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L32e pfam01655
Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and ...
 6-70 3.41e-38

Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and archaebacteria.


:

Pssm-ID: 460283  Cd Length: 108  Bit Score: 122.17  E-value: 3.41e-38
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 352963797    6 TKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:pfam01655   1 TKKFKRHQSDRYKRLKESWRKPRGIDNKVRRRFKGQPPMPKIGYGSPKKTRGLHPSGFKKVLVHN 65
 
Name Accession Description Interval E-value
Ribosomal_L32e pfam01655
Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and ...
 6-70 3.41e-38

Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and archaebacteria.


Pssm-ID: 460283  Cd Length: 108  Bit Score: 122.17  E-value: 3.41e-38
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 352963797    6 TKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:pfam01655   1 TKKFKRHQSDRYKRLKESWRKPRGIDNKVRRRFKGQPPMPKIGYGSPKKTRGLHPSGFKKVLVHN 65
PTZ00159 PTZ00159
60S ribosomal protein L32; Provisional
 1-70 6.98e-37

60S ribosomal protein L32; Provisional


Pssm-ID: 240297  Cd Length: 133  Bit Score: 119.72  E-value: 6.98e-37
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 352963797   1 IVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:PTZ00159  10 IVKKRTKKFTRFQSERFPRVKPSWRKPRGIDNRVRRRFKGTRLMPKIGYGSDKKTRYLLPSGFYKFPVRN 79
Ribosomal_L32_L32e cd00513
Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed ...
 7-70 6.21e-34

Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the A (aminacyl), P (peptidyl) or E (exit) sites of the ribosome, but does interact with 23S rRNA, which has a "kink-turn" secondary structure motif. L32 is overexpressed in human prostate cancer and has been identified as a stably expressed housekeeping gene in macrophages of human chronic obstructive pulmonary disease (COPD) patients. In Schizosaccharomyces pombe, L32 has also been suggested to play a role as a transcriptional regulator in the nucleus. Found in archaea and eukaryotes, this protein is known as L32 in eukaryotes and L32e in archaea.


Pssm-ID: 238284  Cd Length: 107  Bit Score: 111.47  E-value: 6.21e-34
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 352963797   7 KHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:cd00513    1 KKFKRHQSDRYKRLGDSWRKPRGIDNKVRRRFKGKPAMPKIGYGSPKKTRGLHPSGFKKVLVHN 64
Rpl32e COG1717
Ribosomal protein L32E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 1-70 6.13e-19

Ribosomal protein L32E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L32E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441323  Cd Length: 132  Bit Score: 74.12  E-value: 6.13e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 352963797   1 IVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:COG1717   17 KQKRKKPEFKRQDWWKYKRLGDSWRKPRGIDNKQRLQLKGKPPLVKVGYRSPKAVRGLHPSGFEEVLVHN 86
 
Name Accession Description Interval E-value
Ribosomal_L32e pfam01655
Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and ...
 6-70 3.41e-38

Ribosomal protein L32; This family includes ribosomal protein L32 from eukaryotes and archaebacteria.


Pssm-ID: 460283  Cd Length: 108  Bit Score: 122.17  E-value: 3.41e-38
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 352963797    6 TKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:pfam01655   1 TKKFKRHQSDRYKRLKESWRKPRGIDNKVRRRFKGQPPMPKIGYGSPKKTRGLHPSGFKKVLVHN 65
PTZ00159 PTZ00159
60S ribosomal protein L32; Provisional
 1-70 6.98e-37

60S ribosomal protein L32; Provisional


Pssm-ID: 240297  Cd Length: 133  Bit Score: 119.72  E-value: 6.98e-37
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 352963797   1 IVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:PTZ00159  10 IVKKRTKKFTRFQSERFPRVKPSWRKPRGIDNRVRRRFKGTRLMPKIGYGSDKKTRYLLPSGFYKFPVRN 79
Ribosomal_L32_L32e cd00513
Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed ...
 7-70 6.21e-34

Ribosomal_L32_L32e: L32 is a protein from the large subunit that contains a surface-exposed globular domain and a finger-like projection that extends into the RNA core to stabilize the tertiary structure. L32 does not appear to play a role in forming the A (aminacyl), P (peptidyl) or E (exit) sites of the ribosome, but does interact with 23S rRNA, which has a "kink-turn" secondary structure motif. L32 is overexpressed in human prostate cancer and has been identified as a stably expressed housekeeping gene in macrophages of human chronic obstructive pulmonary disease (COPD) patients. In Schizosaccharomyces pombe, L32 has also been suggested to play a role as a transcriptional regulator in the nucleus. Found in archaea and eukaryotes, this protein is known as L32 in eukaryotes and L32e in archaea.


Pssm-ID: 238284  Cd Length: 107  Bit Score: 111.47  E-value: 6.21e-34
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 352963797   7 KHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:cd00513    1 KKFKRHQSDRYKRLGDSWRKPRGIDNKVRRRFKGKPAMPKIGYGSPKKTRGLHPSGFKKVLVHN 64
Rpl32e COG1717
Ribosomal protein L32E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 1-70 6.13e-19

Ribosomal protein L32E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L32E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441323  Cd Length: 132  Bit Score: 74.12  E-value: 6.13e-19
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 352963797   1 IVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:COG1717   17 KQKRKKPEFKRQDWWKYKRLGDSWRKPRGIDNKQRLQLKGKPPLVKVGYRSPKAVRGLHPSGFEEVLVHN 86
rpl32e PRK08562
50S ribosomal protein L32e; Validated
 3-70 5.58e-16

50S ribosomal protein L32e; Validated


Pssm-ID: 236288  Cd Length: 125  Bit Score: 66.49  E-value: 5.58e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 352963797   3 KKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:PRK08562  14 KRKKPEFKRQDWHRYKRLGDKWRRPRGLDSKMRLKLKGKPAIVEVGYRSPKAVRGLHPSGYEEVLVHN 81
PRK12766 PRK12766
50S ribosomal protein L32e; Provisional
 9-70 7.05e-07

50S ribosomal protein L32e; Provisional


Pssm-ID: 183731 [Multi-domain]  Cd Length: 232  Bit Score: 44.07  E-value: 7.05e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 352963797   9 FIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHN 70
Cdd:PRK12766 119 FNRQDYHKKKRTPTSWRRPRGGLSKQRRGIKGKGDTVEAGFRTPTAVRGKHPSGFEEVRVHN 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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