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Transmembrane protein 108 [Heterocephalus glaber]
Protein Classification
TMEM108 domain-containing protein ( domain architecture ID 12174462 )
TMEM108 domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
TMEM108
pfam15759 TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
104-601
0e+00
TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 258 and 575 amino acids in length.
Pssm-ID: 464851 [Multi-domain]
Cd Length: 511
Bit Score: 784.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 104 VVTL G P A PDGP - SQATA T M A TT i PH Q D R HPP IN T T ST VI VTA NI PHSE S PLPTG S PP VT MAT IA SHSE S RPPG D A A PTIL 182
Cdd:pfam15759 1 VVTL E P H PDGP s SQATA S M Q TT - PH P D G HPP TQ T L ST IL VTA VT PHSE G PLPTG P PP AA MAT TE SHSE G RPPG E A V PTIL 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 183 LTKPTG T TS H PTTA AP R AI TRRPPR L PGSSRKG TGA S L RPV P PAP G GH S GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 262
Cdd:pfam15759 80 LTKPTG A TS R PTTA PT R ST TRRPPR P PGSSRKG ASS S S RPV S PAP S GH L GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 263 NFTGS L E --------- TP --- Y F S L PQPQTV AA TTAP R STSW V PPT TL LVPAEDKPGLS T A D QG G GS I FTS P G R EL N TTA 330
Cdd:pfam15759 160 NFTGS V E pdpsaltpr TP lwg Y S S S PQPQTV ST TTAP P STSW R PPT NP LVPAEDKPGLS R A N QG S GS T FTS Q G G EL D TTA 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 331 A A GAPIS S Q AT PVPSQ H PHSD T QD S PS L SDSWLTVT SV TNRPLSASS K VFTA VI GP S QAAF N A T VSAPSQGIPQGTSTTP 410
Cdd:pfam15759 240 A S GAPIS P Q PA PVPSQ K PHSD N QD G PS H SDSWLTVT PN TNRPLSASS G VFTA IQ GP T QAAF D A S VSAPSQGIPQGTSTTP 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 411 QAP AH PPGVSESTVS L AEEEA A A S P F MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA A NISHVAEGDKP H HRATIC 490
Cdd:pfam15759 320 QAP TN PPGVSESTVS I AEEEA T A T P N MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA G NISHVAEGDKP Q HRATIC 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 491 LSKMDI A WVILAISVPISSCSVLLTVCCMRRKK - TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 569
Cdd:pfam15759 400 LSKMDI V WVILAISVPISSCSVLLTVCCMRRKK k TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 479
490 500 510
....*....|....*....|....*....|..
gi 351708557 570 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 601
Cdd:pfam15759 480 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 511
Name
Accession
Description
Interval
E-value
TMEM108
pfam15759 TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
104-601
0e+00
TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 258 and 575 amino acids in length.
Pssm-ID: 464851 [Multi-domain]
Cd Length: 511
Bit Score: 784.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 104 VVTL G P A PDGP - SQATA T M A TT i PH Q D R HPP IN T T ST VI VTA NI PHSE S PLPTG S PP VT MAT IA SHSE S RPPG D A A PTIL 182
Cdd:pfam15759 1 VVTL E P H PDGP s SQATA S M Q TT - PH P D G HPP TQ T L ST IL VTA VT PHSE G PLPTG P PP AA MAT TE SHSE G RPPG E A V PTIL 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 183 LTKPTG T TS H PTTA AP R AI TRRPPR L PGSSRKG TGA S L RPV P PAP G GH S GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 262
Cdd:pfam15759 80 LTKPTG A TS R PTTA PT R ST TRRPPR P PGSSRKG ASS S S RPV S PAP S GH L GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 263 NFTGS L E --------- TP --- Y F S L PQPQTV AA TTAP R STSW V PPT TL LVPAEDKPGLS T A D QG G GS I FTS P G R EL N TTA 330
Cdd:pfam15759 160 NFTGS V E pdpsaltpr TP lwg Y S S S PQPQTV ST TTAP P STSW R PPT NP LVPAEDKPGLS R A N QG S GS T FTS Q G G EL D TTA 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 331 A A GAPIS S Q AT PVPSQ H PHSD T QD S PS L SDSWLTVT SV TNRPLSASS K VFTA VI GP S QAAF N A T VSAPSQGIPQGTSTTP 410
Cdd:pfam15759 240 A S GAPIS P Q PA PVPSQ K PHSD N QD G PS H SDSWLTVT PN TNRPLSASS G VFTA IQ GP T QAAF D A S VSAPSQGIPQGTSTTP 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 411 QAP AH PPGVSESTVS L AEEEA A A S P F MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA A NISHVAEGDKP H HRATIC 490
Cdd:pfam15759 320 QAP TN PPGVSESTVS I AEEEA T A T P N MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA G NISHVAEGDKP Q HRATIC 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 491 LSKMDI A WVILAISVPISSCSVLLTVCCMRRKK - TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 569
Cdd:pfam15759 400 LSKMDI V WVILAISVPISSCSVLLTVCCMRRKK k TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 479
490 500 510
....*....|....*....|....*....|..
gi 351708557 570 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 601
Cdd:pfam15759 480 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 511
PHA03247
PHA03247 large tegument protein UL36; Provisional
77-453
4.09e-09
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 59.95
E-value: 4.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 77 E S L QVLPS G S PP GTMVT A PHSQTTHS SV VTLG PAP DGPSQ A TATM A ttip HQDRH PP INTTSTVI V TANIPHSESPL P TG 156
Cdd:PHA03247 2541 E E L ASDDA G D PP PPLPP A APPAAPDR SV PPPR PAP RPSEP A VTSR A ---- RRPDA PP QSARPRAP V DDRGDPRGPAP P SP 2616
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 157 S PP V T M A ------ TIASHSESRP P GDAAPTILLTK P TGTTSHPTTAA PR A i T RR PP R LPGS S RKGTGASL R PVP P AP G gh 230
Cdd:PHA03247 2617 L PP D T H A pdpppp SPSPAANEPD P HPPPTVPPPER P RDDPAPGRVSR PR R - A RR LG R AAQA S SPPQRPRR R AAR P TV G -- 2693
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 231 sgrkegqrgrnq S S T H L GQKR P LGK ifqiykgnftgslet PYFSL P QPQTV A -- ATTA P RSTSWVP P TTLLV PA EDKPGL 308
Cdd:PHA03247 2694 ------------ S L T S L ADPP P PPP --------------- TPEPA P HALVS A tp LPPG P AAARQAS P ALPAA PA PPAVPA 2746
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 309 ST A DQ GG GSIFTS P grelntt AAAGA P ISSQATPV P SQH P HSDTQDSPSL S D S wltv T S VTNR P LSASSKVFT A VIGPSQ 388
Cdd:PHA03247 2747 GP A TP GG PARPAR P ------- PTTAG P PAPAPPAA P AAG P PRRLTRPAVA S L S ---- E S RESL P SPWDPADPP A AVLAPA 2815
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 351708557 389 AA FNAT v SA P SQGI P QG TS TT P Q AP AH PPG VSESTVS L AEEE A AASPF mt D R V P SPL S TVVST A T 453
Cdd:PHA03247 2816 AA LPPA - AS P AGPL P PP TS AQ P T AP PP PPG PPPPSLP L GGSV A PGGDV -- R R R P PSR S PAAKP A A 2877
Name
Accession
Description
Interval
E-value
TMEM108
pfam15759 TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
104-601
0e+00
TMEM108 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 258 and 575 amino acids in length.
Pssm-ID: 464851 [Multi-domain]
Cd Length: 511
Bit Score: 784.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 104 VVTL G P A PDGP - SQATA T M A TT i PH Q D R HPP IN T T ST VI VTA NI PHSE S PLPTG S PP VT MAT IA SHSE S RPPG D A A PTIL 182
Cdd:pfam15759 1 VVTL E P H PDGP s SQATA S M Q TT - PH P D G HPP TQ T L ST IL VTA VT PHSE G PLPTG P PP AA MAT TE SHSE G RPPG E A V PTIL 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 183 LTKPTG T TS H PTTA AP R AI TRRPPR L PGSSRKG TGA S L RPV P PAP G GH S GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 262
Cdd:pfam15759 80 LTKPTG A TS R PTTA PT R ST TRRPPR P PGSSRKG ASS S S RPV S PAP S GH L GRKEGQRGRNQSSTHLGQKRPLGKIFQIYKG 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 263 NFTGS L E --------- TP --- Y F S L PQPQTV AA TTAP R STSW V PPT TL LVPAEDKPGLS T A D QG G GS I FTS P G R EL N TTA 330
Cdd:pfam15759 160 NFTGS V E pdpsaltpr TP lwg Y S S S PQPQTV ST TTAP P STSW R PPT NP LVPAEDKPGLS R A N QG S GS T FTS Q G G EL D TTA 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 331 A A GAPIS S Q AT PVPSQ H PHSD T QD S PS L SDSWLTVT SV TNRPLSASS K VFTA VI GP S QAAF N A T VSAPSQGIPQGTSTTP 410
Cdd:pfam15759 240 A S GAPIS P Q PA PVPSQ K PHSD N QD G PS H SDSWLTVT PN TNRPLSASS G VFTA IQ GP T QAAF D A S VSAPSQGIPQGTSTTP 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 411 QAP AH PPGVSESTVS L AEEEA A A S P F MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA A NISHVAEGDKP H HRATIC 490
Cdd:pfam15759 320 QAP TN PPGVSESTVS I AEEEA T A T P N MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTA G NISHVAEGDKP Q HRATIC 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 491 LSKMDI A WVILAISVPISSCSVLLTVCCMRRKK - TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 569
Cdd:pfam15759 400 LSKMDI V WVILAISVPISSCSVLLTVCCMRRKK k TANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRS 479
490 500 510
....*....|....*....|....*....|..
gi 351708557 570 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 601
Cdd:pfam15759 480 PANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 511
PHA03247
PHA03247 large tegument protein UL36; Provisional
77-453
4.09e-09
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 59.95
E-value: 4.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 77 E S L QVLPS G S PP GTMVT A PHSQTTHS SV VTLG PAP DGPSQ A TATM A ttip HQDRH PP INTTSTVI V TANIPHSESPL P TG 156
Cdd:PHA03247 2541 E E L ASDDA G D PP PPLPP A APPAAPDR SV PPPR PAP RPSEP A VTSR A ---- RRPDA PP QSARPRAP V DDRGDPRGPAP P SP 2616
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 157 S PP V T M A ------ TIASHSESRP P GDAAPTILLTK P TGTTSHPTTAA PR A i T RR PP R LPGS S RKGTGASL R PVP P AP G gh 230
Cdd:PHA03247 2617 L PP D T H A pdpppp SPSPAANEPD P HPPPTVPPPER P RDDPAPGRVSR PR R - A RR LG R AAQA S SPPQRPRR R AAR P TV G -- 2693
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 231 sgrkegqrgrnq S S T H L GQKR P LGK ifqiykgnftgslet PYFSL P QPQTV A -- ATTA P RSTSWVP P TTLLV PA EDKPGL 308
Cdd:PHA03247 2694 ------------ S L T S L ADPP P PPP --------------- TPEPA P HALVS A tp LPPG P AAARQAS P ALPAA PA PPAVPA 2746
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 309 ST A DQ GG GSIFTS P grelntt AAAGA P ISSQATPV P SQH P HSDTQDSPSL S D S wltv T S VTNR P LSASSKVFT A VIGPSQ 388
Cdd:PHA03247 2747 GP A TP GG PARPAR P ------- PTTAG P PAPAPPAA P AAG P PRRLTRPAVA S L S ---- E S RESL P SPWDPADPP A AVLAPA 2815
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 351708557 389 AA FNAT v SA P SQGI P QG TS TT P Q AP AH PPG VSESTVS L AEEE A AASPF mt D R V P SPL S TVVST A T 453
Cdd:PHA03247 2816 AA LPPA - AS P AGPL P PP TS AQ P T AP PP PPG PPPPSLP L GGSV A PGGDV -- R R R P PSR S PAAKP A A 2877
PHA03247
PHA03247 large tegument protein UL36; Provisional
74-355
3.31e-06
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 50.32
E-value: 3.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 74 QE P ESLQVLPSGSPPGTMVTA P HSQTTH S SVVTLG PAP DGPSQAT AT MAT ti P HQDRH PP INTTSTVIVTANI P HSES P L 153
Cdd:PHA03247 2704 PP P TPEPAPHALVSATPLPPG P AAARQA S PALPAA PAP PAVPAGP AT PGG -- P ARPAR PP TTAGPPAPAPPAA P AAGP P R 2781
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 154 PTGS P P V TMATIASH S ESR P PGD A A P TILLTK P TGTT sh P TT A A P RAITRR P PR - L P GSSRKGT G ASLRPV P P ---- APG 228
Cdd:PHA03247 2782 RLTR P A V ASLSESRE S LPS P WDP A D P PAAVLA P AAAL -- P PA A S P AGPLPP P TS a Q P TAPPPPP G PPPPSL P L ggsv APG 2859
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 229 G HSG R kegq R GRNQ S STHLGQKRPLGKIFQIYKGNFTG S L E T py F S LP QP Q ----- TVA A TTA P RSTSWV PP TTLLV P AE 303
Cdd:PHA03247 2860 G DVR R ---- R PPSR S PAAKPAAPARPPVRRLARPAVSR S T E S -- F A LP PD Q perpp QPQ A PPP P QPQPQP PP PPQPQ P PP 2933
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 351708557 304 DK P GLS --------- T A DQ G GG S IFTS -------- PGR ELNTTAAAGA P IS S QAT P VP S QH P HSDTQD S 355
Cdd:PHA03247 2934 PP P PRP qpplapttd P A GA G EP S GAVP qpwlgalv PGR VAVPRFRVPQ P AP S REA P AS S TP P LTGHSL S 3002
PHA03247
PHA03247 large tegument protein UL36; Provisional
83-453
5.63e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 43.39
E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 83 PS G S P P G TMVTA P HSQT TH SSV vtl G P A P DGPSQ A TA ----- TMATTI P HQD R HP P ---- INTTSTVIVTANIPHSE SP L 153
Cdd:PHA03247 2604 DR G D P R G PAPPS P LPPD TH APD --- P P P P SPSPA A NE pdphp PPTVPP P ERP R DD P apgr VSRPRRARRLGRAAQAS SP P 2680
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 154 PTGSPPVTMA T IA S HSESRP P GDAA PT --------- ILLTK P T G TTSHPTTAAPRAITRR PP RL P GSSRKGT G ASLRPV P 224
Cdd:PHA03247 2681 QRPRRRAARP T VG S LTSLAD P PPPP PT pepaphalv SATPL P P G PAAARQASPALPAAPA PP AV P AGPATPG G PARPAR P 2760
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 225 P APG G h SGRKEGQRGRNQSSTHLGQKRPLGKIFQIYKGNFTGSLETPYFSLPQPQTV A ATT A PRSTSWV PP T T LLV P A -- 302
Cdd:PHA03247 2761 P TTA G - PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA A LPP A ASPAGPL PP P T SAQ P T ap 2839
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 303 - EDKPGLSTADQG GGS IFT ------- S P G R ELNTTA AA G A -- P ISSQ A T P VP S QHPH S ----- D TQDS P SLSDSWLTVTS 367
Cdd:PHA03247 2840 p PPPGPPPPSLPL GGS VAP ggdvrrr P P S R SPAAKP AA P A rp P VRRL A R P AV S RSTE S falpp D QPER P PQPQAPPPPQP 2919
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 368 VTNR P LSASSKVFTAVIGPS Q AAFNA T VSAPSQ G I P Q G TSTT P QAP A HP PG VSESTVSLAEEE A AASPFMTDRV P SPLST 447
Cdd:PHA03247 2920 QPQP P PPPQPQPPPPPPPRP Q PPLAP T TDPAGA G E P S G AVPQ P WLG A LV PG RVAVPRFRVPQP A PSREAPASST P PLTGH 2999
....*.
gi 351708557 448 VV S TAT 453
Cdd:PHA03247 3000 SL S RVS 3005
Herpes_BLLF1
pfam05109 Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
81-345
1.94e-03
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain]
Cd Length: 886
Bit Score: 41.44
E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 81 V L PS G SP -- P GT MVT AP HSQTTH S S V V T LG P APDG P SQ A tat MA T TI P HQDRHPPIN T TS T VI VT ANI P HSE SP L P TGSP 158
Cdd:pfam05109 488 V T PS P SP rd N GT ESK AP DMTSPT S A V T T PT P NATS P TP A --- VT T PT P NATSPTLGK T SP T SA VT TPT P NAT SP T P AVTT 564
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 159 P VTM ATI ASH sesrpp G DAA PT ILL T K PT GTTSH PT taapra ITRRP P RLPGSSRKGT G A S LR PV PPA P -- GGH S GRKE G 236
Cdd:pfam05109 565 P TPN ATI PTL ------ G KTS PT SAV T T PT PNATS PT ------ VGETS P QANTTNHTLG G T S ST PV VTS P pk NAT S AVTT G 632
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 237 Q RGRNQ SST HLGQK RP LGKIFQIYKGN ---------- F T GSLE T PYFSLP Q PQTVAAT T APR STS WVP P TTLLVPAEDK P 306
Cdd:pfam05109 633 Q HNITS SST SSMSL RP SSISETLSPST sdnstshmpl L T SAHP T GGENIT Q VTPASTS T HHV STS SPA P RPGTTSQASG P 712
250 260 270
....*....|....*....|....*....|....*....
gi 351708557 307 G L S TADQGG G SIFTSP G RELNTTAAAG AP i S S Q A T P VP S 345
Cdd:pfam05109 713 G N S STSTKP G EVNVTK G TPPKNATSPQ AP - S G Q K T A VP T 750
PHA03378
PHA03378 EBNA-3B; Provisional
76-418
2.10e-03
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain]
Cd Length: 991
Bit Score: 41.21
E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 76 PES LQ VL P SG SP PGTMV -- T AP HSQT T HSS V VTLGPA P DG P SQATATMA T TI P H Q DRH P -- PI NTTSTVIVTANIPHSES 151
Cdd:PHA03378 569 LGP LQ IQ P LT SP TTSQL as S AP SYAQ T PWP V PHPSQT P EP P TTQSHIPE T SA P R Q WPM P lr PI PMRPLRMQPITFNVLVF 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 152 P L P TGS P P V TMA ---------------- TIASHSESR P P g DA AP TILLTK P TGT T SHPTT AAP RAITR RP PRLP G SS R KG 215
Cdd:PHA03378 649 P T P HQP P Q V EIT pykptwtqighipyqp SPTGANTML P I - QW AP GTMQPP P RAP T PMRPP AAP PGRAQ RP AAAT G RA R PP 727
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 216 TG A SL R PV PPA PGG hsgrkeg Q R G R NQSSTHLGQKR P LGKIFQIYKGNFTGSLE TP yfs L P Q PQ TVA A TT ------- A P R 288
Cdd:PHA03378 728 AA A PG R AR PPA AAP ------- G R A R PPAAAPGRARP P AAAPGRARPPAAAPGAP TP --- Q P P PQ APP A PQ qrprgap T P Q 797
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 289 STSWVP PT TLLVPAEDK PG LS - TAD Q GGGSIF T SPGRELNTTAAAG A PISS QA TPV P SQH P H S D T Q D S pslsdswltvts 367
Cdd:PHA03378 798 PPPQAG PT SMQLMPRAA PG QQ g PTK Q ILRQLL T GGVKRGRPSLKKP A ALER QA AAG P TPS P G S G T S D K ------------ 865
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 351708557 368 VTNR P L sassk VFTA V IG P S Q AAFNATVSAPS qgipq GT ST TP QAP AHPP G 418
Cdd:PHA03378 866 IVQA P V ----- FYPP V LQ P I Q VMRQLGSVRAA ----- AA ST VT QAP TEYT G 906
PHA03247
PHA03247 large tegument protein UL36; Provisional
154-472
5.13e-03
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 39.92
E-value: 5.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 154 PTGS P PVTMATIASHSESRP P GDA AP T IL LTK P T G TTS HP TTAA ----------------- P RAITRR PP RL P GS S RKGT 216
Cdd:PHA03247 2492 AGAA P DPGGGGPPDPDAPPA P SRL AP A IL PDE P V G EPV HP RMLT wirgleelasddagdpp P PLPPAA PP AA P DR S VPPP 2571
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 217 GASL RP VP PA PGGHSG R KEGQRGRNQSSTHLGQKRP lgkifqi YK G NFTG S LET P YFSL P Q P Q tv AATTA P RSTSWV P PT 296
Cdd:PHA03247 2572 RPAP RP SE PA VTSRAR R PDAPPQSARPRAPVDDRGD ------- PR G PAPP S PLP P DTHA P D P P -- PPSPS P AANEPD P HP 2642
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 297 TLL VP AEDK P GLST A ----------- DQ G GGSIFT SP GRELNTT AA -- AGAPIS S Q A T P V P sqh P HSDTQDS P SLSD S WL 363
Cdd:PHA03247 2643 PPT VP PPER P RDDP A pgrvsrprrar RL G RAAQAS SP PQRPRRR AA rp TVGSLT S L A D P P P --- P PPTPEPA P HALV S AT 2719
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 364 TVTSVTNRPLS AS SKVFT A VIG P SQA A FN AT VSA P SQ - GI P QG T S ----- TT P Q APA HP P GVSESTVSL A EEEAAASPFM 437
Cdd:PHA03247 2720 PLPPGPAAARQ AS PALPA A PAP P AVP A GP AT PGG P AR p AR P PT T A gppap AP P A APA AG P PRRLTRPAV A SLSESRESLP 2799
330 340 350
....*....|....*....|....*....|....*
gi 351708557 438 TDRV P SPLSTV V STATGNFLNRLV PAG TWK P G T A A 472
Cdd:PHA03247 2800 SPWD P ADPPAA V LAPAAALPPAAS PAG PLP P P T S A 2834
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
75-435
7.70e-03
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 39.38
E-value: 7.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 75 E P E S LQVLP S GS PPG TMVTA P HSQ T THSSVVTLG PAPD GPSQATATMATTI P HQDRH P PINTTSTVIVTANIPHSESP LP 154
Cdd:PHA03307 96 A P A S PAREG S PT PPG PSSPD P PPP T PPPASPPPS PAPD LSEMLRPVGSPGP P PAASP P AAGASPAAVASDAASSRQAA LP 175
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 155 TG SP PV T MATIA S HSESR PP gd AA P TILLTKPTGTT S H P TT A APRAITRR P P R LPGSSRKGTGASLRPVPPAPG G HSGRK 234
Cdd:PHA03307 176 LS SP EE T ARAPS S PPAEP PP -- ST P PAAASPRPPRR S S P IS A SASSPAPA P G R SAADDAGASSSDSSSSESSGC G WGPEN 253
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 235 E GQRG R NQSS T HLGQKR plgkifqiykgnf TG S LETPYF S L P Q P QTVAATTAP RS T S WV P pttllv PAEDKPGLSTADQG 314
Cdd:PHA03307 254 E CPLP R PAPI T LPTRIW ------------- EA S GWNGPS S R P G P ASSSSSPRE RS P S PS P ------ SSPGSGPAPSSPRA 314
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 315 GG S IFT S PGRELNT T AAAGAPISSQ A TP v P SQH P HSDT qd SPS LSDSWLTVT S VTN RP LSASSKVFT A VIGPSQAAFN A T 394
Cdd:PHA03307 315 SS S SSS S RESSSSS T SSSSESSRGA A VS - P GPS P SRSP -- SPS RPPPPADPS S PRK RP RPSRAPSSP A ASAGRPTRRR A R 391
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 351708557 395 VSAPSQGIPQ gt ST T PQA PA HP P GV S ESTVSL A EEEAA A SP 435
Cdd:PHA03307 392 AAVAGRARRR -- DA T GRF PA GR P RP S PLDAGA A SGAFY A RY 430
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
71-451
8.69e-03
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 39.37
E-value: 8.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 71 LAI Q EPESLQVL PS GS PPGT mvtaphsqtth SSVV T L GP A P DG PS - QATATM AT TI P HQDRHPPINTTSTVIV T ANIPHS 149
Cdd:pfam03154 172 PVL Q AQSGAASP PS PP PPGT ----------- TQAA T A GP T P SA PS v PPQGSP AT SQ P PNQTQSTAAPHTLIQQ T PTLHPQ 240
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 150 E sp LP TGS PP VTMA T IASHSESRP P g DAA P TIL L TKPTGTTS H PTTAA P RAITRRP P RL P GSSRKGTGA S LR P VP P A P G - 228
Cdd:pfam03154 241 R -- LP SPH PP LQPM T QPPPPSQVS P - QPL P QPS L HGQMPPMP H SLQTG P SHMQHPV P PQ P FPLTPQSSQ S QV P PG P S P A a 317
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 229 GHSGRKEGQRGRN QS STHLG Q --- KR PL GKI f QIYKGNFTGSLE TP YFS LP Q PQ T ------ VAATTAPRST S WV PP TTL L 299
Cdd:pfam03154 318 PGQSQQRIHTPPS QS QLQSQ Q ppr EQ PL PPA - PLSMPHIKPPPT TP IPQ LP N PQ S hkhpph LSGPSPFQMN S NL PP PPA L 396
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 300 V ---------- P AEDK P G L STAD Q g GGSIFTS P GRELNT T ------- A AA GA P IS S QATP VPSQ H P HSDTQDS P SLSDS w 362
Cdd:pfam03154 397 K plsslsthhp P SAHP P P L QLMP Q - SQQLPPP P AQPPVL T qsqslpp P AA SH P PT S GLHQ VPSQ S P FPQHPFV P GGPPP - 474
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351708557 363 lt V T SVTNR P L S A SS KV ftavigpsqaafn ATVSA PS QGIPQGTSTT P Q A PAH P - P G V SESTVS L A E E E AAA SP FMTD R V 441
Cdd:pfam03154 475 -- I T PPSGP P T S T SS AM ------------- PGIQP PS SASVSSSGPV P A A VSC P l P P V QIKEEA L D E A E EPE SP PPPP R S 539
410
....*....|
gi 351708557 442 PSP LS TVV S T 451
Cdd:pfam03154 540 PSP EP TVV N T 549
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
