NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|346422941|gb|AEO24466|]
View 

conserved hypothetical protein [Listeria monocytogenes FSL R2-561]

Protein Classification

tRNA1(Val) (adenine(37)-N6)-methyltransferase( domain architecture ID 11467886)

tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase is a class I SAM-dependent methyltransferase that specifically methylates the adenine in position 37 of tRNA(1)(Val)

CATH:  2.20.25.110
EC:  2.1.1.223
Gene Ontology:  GO:0016430|GO:1904047|GO:0008170|GO:0032259|GO:0008757
PubMed:  12826405|12504684
SCOP:  3000118

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 13-251 2.94e-110

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 317.09  E-value: 2.94e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  13 ERLDYLLAENLRIIQSPSVFSFSIDAVLLAKFSYLPvRKGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKR 91
Cdd:COG4123    1 ERLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVK-KGGRVLDLGTGTGVIALMLAQRSpGARITGVEIQPEAAELARR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  92 SISYNQLEEQIEMIEYDLKNITDLIPKERADIVTCNPPYFaTPDTSLKNTNEHFRIARHEVMCTLEDTIRVAASLLKQGG 171
Cdd:COG4123   80 NVALNGLEDRITVIHGDLKEFAAELPPGSFDLVVSNPPYF-KAGSGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941 172 KANFVHRPERLLDIIDIMRKYRLEPKRIQFVHPRIDKEANTVLVEGIKDGKPGVKYVPPVIVYDELGEYTPVIKEILYGE 251
Cdd:COG4123  159 RFALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRILPPLVIHDEDGEYTPEVKALLRDF 238
 
Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 13-251 2.94e-110

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 317.09  E-value: 2.94e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  13 ERLDYLLAENLRIIQSPSVFSFSIDAVLLAKFSYLPvRKGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKR 91
Cdd:COG4123    1 ERLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVK-KGGRVLDLGTGTGVIALMLAQRSpGARITGVEIQPEAAELARR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  92 SISYNQLEEQIEMIEYDLKNITDLIPKERADIVTCNPPYFaTPDTSLKNTNEHFRIARHEVMCTLEDTIRVAASLLKQGG 171
Cdd:COG4123   80 NVALNGLEDRITVIHGDLKEFAAELPPGSFDLVVSNPPYF-KAGSGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941 172 KANFVHRPERLLDIIDIMRKYRLEPKRIQFVHPRIDKEANTVLVEGIKDGKPGVKYVPPVIVYDELGEYTPVIKEILYGE 251
Cdd:COG4123  159 RFALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRILPPLVIHDEDGEYTPEVKALLRDF 238
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 22-172 2.38e-10

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 57.60  E-value: 2.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941   22 NLRIIQSPSVFSF-SID---AVLLakfSYLPVR-KGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKRSISY 95
Cdd:pfam05175   1 ELTFKTLPGVFSHgRLDigsRLLL---EHLPKDlSGKVLDLGCGAGVLGAALAKESpDAELTMVDINARALESARENLAA 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 346422941   96 NQLEEqiemIEYDLKNITDLIPKERADIVTCNPPyfatpdtslkntnehFRIARHEVMCTLEDTIRVAASLLKQGGK 172
Cdd:pfam05175  78 NGLEN----GEVVASDVYSGVEDGKFDLIISNPP---------------FHAGLATTYNVAQRFIADAKRHLRPGGE 135
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 53-172 8.53e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 49.35  E-value: 8.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  53 KIIDLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRsISYNQLEEQIEMIEYDLKNItDLIPKERADIVTCNPPYFA 132
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARK-AAAALLADNVEVLKGDAEEL-PPEADESFDVIISDPPLHH 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 346422941 133 TPDtslkntnehfriarhevmcTLEDTIRVAASLLKQGGK 172
Cdd:cd02440   79 LVE-------------------DLARFLEEARRLLKPGGV 99
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 36-130 1.26e-07

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 51.32  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  36 IDAVLLAKfsyLPVRKGKIIDLCSGNGIIPL-LLSTRTEAQIVGVEIQERLADMAKRSISYNqLEEQIEMIEYDLkniTD 114
Cdd:PRK09328  97 VEWALEAL---LLKEPLRVLDLGTGSGAIALaLAKERPDAEVTAVDISPEALAVARRNAKHG-LGARVEFLQGDW---FE 169

                         90
                 ....*....|....*.
gi 346422941 115 LIPKERADIVTCNPPY 130
Cdd:PRK09328 170 PLPGGRFDLIVSNPPY 185
 
Name Accession Description Interval E-value
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 13-251 2.94e-110

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 317.09  E-value: 2.94e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  13 ERLDYLLAENLRIIQSPSVFSFSIDAVLLAKFSYLPvRKGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKR 91
Cdd:COG4123    1 ERLDGFLFKQFRIIQPRCGYRFGTDAVLLAAFAPVK-KGGRVLDLGTGTGVIALMLAQRSpGARITGVEIQPEAAELARR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  92 SISYNQLEEQIEMIEYDLKNITDLIPKERADIVTCNPPYFaTPDTSLKNTNEHFRIARHEVMCTLEDTIRVAASLLKQGG 171
Cdd:COG4123   80 NVALNGLEDRITVIHGDLKEFAAELPPGSFDLVVSNPPYF-KAGSGRKSPDEARAIARHEDALTLEDLIRAAARLLKPGG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941 172 KANFVHRPERLLDIIDIMRKYRLEPKRIQFVHPRIDKEANTVLVEGIKDGKPGVKYVPPVIVYDELGEYTPVIKEILYGE 251
Cdd:COG4123  159 RFALIHPAERLAEILAALRKYGLGPKRLRPVHPRPGKPAKRVLLEARKGGRAGLRILPPLVIHDEDGEYTPEVKALLRDF 238
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 18-176 8.32e-13

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 64.83  E-value: 8.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  18 LLAENLRIIQSPSVFSF-SID---AVLLakfSYLPVR-KGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKR 91
Cdd:COG2813   15 LAGRDLTFVTLPGVFSRdRLDigtRLLL---EHLPEPlGGRVLDLGCGYGVIGLALAKRNpEARVTLVDVNARAVELARA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  92 SISYNQLEEqiemIEYDLKNITDLIPKERADIVTCNPPyfatpdtslkntnehFRIARHEVMCTLEDTIRVAASLLKQGG 171
Cdd:COG2813   92 NAAANGLEN----VEVLWSDGLSGVPDGSFDLILSNPP---------------FHAGRAVDKEVAHALIADAARHLRPGG 152


                 ....*
gi 346422941 172 KANFV 176
Cdd:COG2813  153 ELWLV 157
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 50-130 1.02e-10

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 60.55  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  50 RKGKIIDLCSGNGIIPL-LLSTRTEAQIVGVEIQERLADMAKRSISYNQLEEQIEMIEYDLknITDLIPKERADIVTCNP 128
Cdd:COG2890  112 APPRVLDLGTGSGAIALaLAKERPDARVTAVDISPDALAVARRNAERLGLEDRVRFLQGDL--FEPLPGDGRFDLIVSNP 189


                 ..
gi 346422941 129 PY 130
Cdd:COG2890  190 PY 191
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 22-172 2.38e-10

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 57.60  E-value: 2.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941   22 NLRIIQSPSVFSF-SID---AVLLakfSYLPVR-KGKIIDLCSGNGIIPLLLSTRT-EAQIVGVEIQERLADMAKRSISY 95
Cdd:pfam05175   1 ELTFKTLPGVFSHgRLDigsRLLL---EHLPKDlSGKVLDLGCGAGVLGAALAKESpDAELTMVDINARALESARENLAA 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 346422941   96 NQLEEqiemIEYDLKNITDLIPKERADIVTCNPPyfatpdtslkntnehFRIARHEVMCTLEDTIRVAASLLKQGGK 172
Cdd:pfam05175  78 NGLEN----GEVVASDVYSGVEDGKFDLIISNPP---------------FHAGLATTYNVAQRFIADAKRHLRPGGE 135
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 53-172 8.53e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 49.35  E-value: 8.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  53 KIIDLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRsISYNQLEEQIEMIEYDLKNItDLIPKERADIVTCNPPYFA 132
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARK-AAAALLADNVEVLKGDAEEL-PPEADESFDVIISDPPLHH 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 346422941 133 TPDtslkntnehfriarhevmcTLEDTIRVAASLLKQGGK 172
Cdd:cd02440   79 LVE-------------------DLARFLEEARRLLKPGGV 99
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 36-130 1.26e-07

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 51.32  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  36 IDAVLLAKfsyLPVRKGKIIDLCSGNGIIPL-LLSTRTEAQIVGVEIQERLADMAKRSISYNqLEEQIEMIEYDLkniTD 114
Cdd:PRK09328  97 VEWALEAL---LLKEPLRVLDLGTGSGAIALaLAKERPDAEVTAVDISPEALAVARRNAKHG-LGARVEFLQGDW---FE 169

                         90
                 ....*....|....*.
gi 346422941 115 LIPKERADIVTCNPPY 130
Cdd:PRK09328 170 PLPGGRFDLIVSNPPY 185
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
49-126 3.49e-07

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 49.65  E-value: 3.49e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 346422941  49 VRKGKII-DLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRSISYNQLEEQIEMIEydlKNITDLIPKERADIVTC 126
Cdd:COG4076   33 VKPGDVVlDIGTGSGLLSMLAARAGAKKVYAVEVNPDIAAVARRIIAANGLSDRITVIN---ADATDLDLPEKADVIIS 108
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 54-171 4.50e-07

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 46.79  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941   54 IIDLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRSISYNQLEeqiemIEYDLKNITDL-IPKERADIVTCNppyfa 132
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLN-----VEFVQGDAEDLpFPDGSFDLVVSS----- 70

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 346422941  133 tpdtslkNTNEHFRIARhevmctLEDTIRVAASLLKQGG 171
Cdd:pfam13649  71 -------GVLHHLPDPD------LEAALREIARVLKPGG 96
PRK14968 PRK14968
putative methyltransferase; Provisional
 29-135 1.03e-05

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 44.89  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  29 PSVFSFSIDAVLLAKfsYLPVRKG-KIIDLCSGNGIIPLLLSTRtEAQIVGVEIQERLADMAKRSISYNQL-EEQIEMIE 106
Cdd:PRK14968   3 DEVYEPAEDSFLLAE--NAVDKKGdRVLEVGTGSGIVAIVAAKN-GKKVVGVDINPYAVECAKCNAKLNNIrNNGVEVIR 79

                         90       100       110
                 ....*....|....*....|....*....|
gi 346422941 107 YDL-KNITDlipkERADIVTCNPPYFATPD 135
Cdd:PRK14968  80 SDLfEPFRG----DKFDVILFNPPYLPTEE 105
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
46-171 6.52e-05

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 42.29  E-value: 6.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  46 YLPVRKGKIIDLCSGNGIIPLLLSTRTeAQIVGVEIQERLADMAKRSISYNQLEEQiemieydlkNITDL-IPKERADIV 124
Cdd:COG4976   42 LPPGPFGRVLDLGCGTGLLGEALRPRG-YRLTGVDLSEEMLAKAREKGVYDRLLVA---------DLADLaEPDGRFDLI 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 346422941 125 TCNppyfatpdtslkntnehfriarhEVMCTLEDTIRV---AASLLKQGG 171
Cdd:COG4976  112 VAA-----------------------DVLTYLGDLAAVfagVARALKPGG 138
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
52-171 1.22e-04

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 40.19  E-value: 1.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  52 GKIIDLCSGNGIIPLLLSTR-TEAQIVGVEIQERLADMAKRSISYnqleeqiemIEYDLKNITDLIPKERADIVTCNppy 130
Cdd:COG4106    3 RRVLDLGCGTGRLTALLAERfPGARVTGVDLSPEMLARARARLPN---------VRFVVADLRDLDPPEPFDLVVSN--- 70

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 346422941 131 fatpdTSLkntneHFrIARHEVMctledtIRVAASLLKQGG 171
Cdd:COG4106   71 -----AAL-----HW-LPDHAAL------LARLAAALAPGG 94
PRK15001 PRK15001
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;
51-130 1.25e-04

23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;


Pssm-ID: 184963 [Multi-domain]  Cd Length: 378  Bit Score: 42.71  E-value: 1.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  51 KGKIIDLCSGNGIIPL-LLSTRTEAQIVGVEIQERLADMAKRSISYNqLEEQIEMIEYDLKNITDLIPKERADIVTCNPP 129
Cdd:PRK15001 229 EGEIVDLGCGNGVIGLtLLDKNPQAKVVFVDESPMAVASSRLNVETN-MPEALDRCEFMINNALSGVEPFRFNAVLCNPP 307


                 .
gi 346422941 130 Y 130
Cdd:PRK15001 308 F 308
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 47-177 4.73e-04

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 39.53  E-value: 4.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  47 LPVRKG-KIIDLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRSISYNQLEEQIEMIEYDLkniTDLIPKERADIVT 125
Cdd:COG2230   47 LGLKPGmRVLDIGCGWGGLALYLARRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADY---RDLPADGQFDAIV 123

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 346422941 126 CNppyfatpdtslkNTNEHFRIARhevmctLEDTIRVAASLLKQGGKAnFVH 177
Cdd:COG2230  124 SI------------GMFEHVGPEN------YPAYFAKVARLLKPGGRL-LLH 156
PHA03411 PHA03411
putative methyltransferase; Provisional
 52-144 5.82e-04

putative methyltransferase; Provisional


Pssm-ID: 177639 [Multi-domain]  Cd Length: 279  Bit Score: 40.47  E-value: 5.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  52 GKIIDLCSGNGIIPLLLSTRTEAQ-IVGVEIQERLADMAKRsisynqLEEQIEMIEYDlknITDLIPKERADIVTCNPPY 130
Cdd:PHA03411  66 GKVLDLCAGIGRLSFCMLHRCKPEkIVCVELNPEFARIGKR------LLPEAEWITSD---VFEFESNEKFDVVISNPPF 136

                         90
                 ....*....|....
gi 346422941 131 FATPDTSLKNTNEH 144
Cdd:PHA03411 137 GKINTTDTKDVFEY 150
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
53-129 6.42e-04

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 39.50  E-value: 6.42e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 346422941  53 KIIDLCSGNGIIPLLLSTRTEAQIVGVEIQERLADMAKRSISynQLEEQIEMIEYDlknITDLIPKERADIVTCNPP 129
Cdd:COG2263   48 TVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENAE--RLGVRVDFIRAD---VTRIPLGGSVDTVVMNPP 119
rsmC PRK09489
16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC;
21-184 8.79e-04

16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC;


Pssm-ID: 181902 [Multi-domain]  Cd Length: 342  Bit Score: 39.92  E-value: 8.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  21 ENLRIIQSPSVFSF-SIDA---VLLAKFSylPVRKGKIIDLCSGNGIIPLLLSTRTEaqivgvEIQERLADM-------A 89
Cdd:PRK09489 165 DGLTVKTLPGVFSRdGLDVgsqLLLSTLT--PHTKGKVLDVGCGAGVLSAVLARHSP------KIRLTLSDVsaaalesS 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 346422941  90 KRSISYNQLEEQIemIEYDL-KNItdlipKERADIVTCNPPYFATPDTSLKntnehfriarhevmcTLEDTIRVAASLLK 168
Cdd:PRK09489 237 RATLAANGLEGEV--FASNVfSDI-----KGRFDMIISNPPFHDGIQTSLD---------------AAQTLIRGAVRHLN 294

                        170       180
                 ....*....|....*....|.
gi 346422941 169 QGGK----AN-FVHRPErLLD 184
Cdd:PRK09489 295 SGGElrivANaFLPYPD-LLD 314
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH