|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
4-404 |
0e+00 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 761.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSV 83
Cdd:PRK08242 3 EAYIYDAVRTPRGKGKKDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADIARTAVLAAGLPETV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGPMMLDPAVSMQIGFVPQGIGADLIATIEGFT 163
Cdd:PRK08242 83 PGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSDGGAWAMDPSTNFPTYFVPQGISADLIATKYGFS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 164 REDVDRYALCSQQRAAHARANGYF-KSIVPVRDQNGLVVLAEDEHIRPDTTLEALAALPPAFEMMGAM-GFDDVALQKYV 241
Cdd:PRK08242 163 REDVDAYAVESQQRAAAAWAEGYFaKSVVPVKDQNGLTILDHDEHMRPGTTMESLAKLKPSFAMMGEMgGFDAVALQKYP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 242 TVERINHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDL 321
Cdd:PRK08242 243 EVERINHVHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALAKAGLTVDDIDL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 322 IEVNEAFAAVVLKFMRDMGLEDegpERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATII 401
Cdd:PRK08242 323 FELNEAFASVVLRFMQALDIPH---DKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLCVGGGMGIATII 399
|
...
gi 345112616 402 ERV 404
Cdd:PRK08242 400 ERV 402
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
4-404 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 530.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKttGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSV 83
Cdd:COG0183 3 EVVIVDAVRTPFGRFG--GALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAG-QGQNPARQAALLAGLPESV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGP-----------MMLDPAVSMQIGFVPQGIG 152
Cdd:COG0183 80 PAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARwgyrmnaklvdPMINPGLTDPYTGLSMGET 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 153 ADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK-SIVPV--RDQNGLVVLAEDEHIRPDTTLEALAALPPAFEMMGa 229
Cdd:COG0183 160 AENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDdEIVPVevPDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFKKDG- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 230 mgfddvalqkyvtverinhVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKAL 309
Cdd:COG0183 239 -------------------TVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKAL 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 310 QKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITL 389
Cdd:COG0183 300 ARAGLTLDDIDLIEINEAFAAQVLAVLRELGLD---PDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATM 376
|
410
....*....|....*
gi 345112616 390 CVGGGMGIATIIERV 404
Cdd:COG0183 377 CIGGGQGIALIIERV 391
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
6-403 |
5.23e-172 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 485.83 E-value: 5.23e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 6 YVFDAIRTPRGRGKttGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEqGGNIAKTAALYAGWDLSVPG 85
Cdd:cd00751 1 VIVSAVRTPIGRFG--GALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGE-GQNPARQAALLAGLPESVPA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 86 VQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGPM-----------MLDPAVSMQIGFVPQGIGAD 154
Cdd:cd00751 78 TTVNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRggrlglntldgMLDDGLTDPFTGLSMGITAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 155 LIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRDQN--GLVVLAEDEHIRPDTTLEALAALPPAFEMmgamg 231
Cdd:cd00751 158 NVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDeIVPVEVPGrkGPVVVDRDEGPRPDTTLEKLAKLKPAFKK----- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 232 fddvalqkyvtveriNHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQK 311
Cdd:cd00751 233 ---------------DGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKR 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 312 AGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCV 391
Cdd:cd00751 298 AGLTLDDIDLIEINEAFAAQALACLKELGLD---PEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCI 374
|
410
....*....|..
gi 345112616 392 GGGMGIATIIER 403
Cdd:cd00751 375 GGGQGAAMVIER 386
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
7-402 |
5.09e-152 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 435.12 E-value: 5.09e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 7 VFDAIRTPRGrgKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGgNIAKTAALYAGWDLSVPGV 86
Cdd:TIGR01930 1 IVAAARTPIG--KFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQ-NIARQAALLAGLPESVPAY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 87 QINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMG-SDGGPMMLDPAVS-----------MQIGFVPQGIGAD 154
Cdd:TIGR01930 78 TVNRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGvPRSLRWGVKPGNAeledarlkdltDANTGLPMGVTAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 155 LIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRDQ--NGLVVLAEDEHIRPDTTLEALAALPPAFemmgamg 231
Cdd:TIGR01930 158 NLAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDeIVPVTVKgrKGPVTVSSDEGIRPNTTLEKLAKLKPAF------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 232 fddvalqkyvtveRINHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQK 311
Cdd:TIGR01930 231 -------------DPDGTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 312 AGMTLDDIDLIEVNEAFAAVVLKFMRDMGLedeGPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCV 391
Cdd:TIGR01930 298 AGLSISDIDLFEINEAFAAQVLACIKELGL---DLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCI 374
|
410
....*....|.
gi 345112616 392 GGGMGIATIIE 402
Cdd:TIGR01930 375 GGGQGAAVILE 385
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
4-404 |
1.12e-151 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 435.36 E-value: 1.12e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKT-TGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLS 82
Cdd:PRK06025 3 EAYIIDAVRTPRGIGKVgKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGGDLGRMAALDAGYDIK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMS------RVPMGSDGGPMMLDPAVSMQIGFVPQ---GIGA 153
Cdd:PRK06025 83 ASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytaamaAEDMAAGKPPLGMGSGNLRLRALHPQshqGVCG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 154 DLIATIEGFTREDVDRYALCSQQRAAHARANGYF-KSIVPVRDQNGLVVLAEDEHIRPDTTLEALAALPPAFEMMGAMGF 232
Cdd:PRK06025 163 DAIATMEGITREALDALGLESQRRAARAIKEGRFdKSLVPVYRDDGSVALDHEEFPRPQTTAEGLAALKPAFTAIADYPL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 233 DD-------VALQKYVTVErINHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPAS 305
Cdd:PRK06025 243 DDkgttyrgLINQKYPDLE-IKHVHHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLNAPVPAA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 306 KKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDegpERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTA 385
Cdd:PRK06025 322 KKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDR---DKVNVNGGAIALGHPIGATGSILIGTVLDELERRGLKRG 398
|
410
....*....|....*....
gi 345112616 386 LITLCVGGGMGIATIIERV 404
Cdd:PRK06025 399 LVTMCAAGGMAPAIIIERV 417
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
4-404 |
3.68e-134 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 389.90 E-value: 3.68e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRgkTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSV 83
Cdd:PRK05790 3 DVVIVSAARTPIGK--FGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAG-AGQNPARQAALKAGLPVEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP---MGSDGGPMMLDPAV--SM-------QIGFVPQGI 151
Cdd:PRK05790 80 PALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPhvlPGSRWGQKMGDVELvdTMihdgltdAFNGYHMGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 152 GADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVR--DQNG-LVVLAEDEHIRPDTTLEALAALPPAFEMM 227
Cdd:PRK05790 160 TAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDeIVPVTikQRKGdPVVVDTDEHPRPDTTAESLAKLRPAFDKD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 228 GamgfddvalqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKK 307
Cdd:PRK05790 240 G-------------TV-------TAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRK 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 308 ALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALI 387
Cdd:PRK05790 300 ALEKAGWSLADLDLIEINEAFAAQALAVEKELGLD---PEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLA 376
|
410
....*....|....*..
gi 345112616 388 TLCVGGGMGIATIIERV 404
Cdd:PRK05790 377 TLCIGGGQGVALIVERP 393
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
4-404 |
6.11e-124 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 364.27 E-value: 6.11e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRgkTTGSLYEVKPIDLLTTLFAELKRRH-ELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLS 82
Cdd:PRK09050 3 EAFICDAIRTPIGR--YGGALSSVRADDLGAVPLKALMARNpGVDWEAVDDVIYGCANQAGEDNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP--MGSDGGPM--------------MLDPAVSMQIGF 146
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPfvMGKADSAFsrqaeifdttigwrFVNPLMKAQYGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 147 VPQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYF-KSIVPV---RDQNGLVVLAEDEHIRPDTTLEALAALPP 222
Cdd:PRK09050 161 DSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLaEEIVPVtipQKKGDPVVVDRDEHPRPETTLEALAKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 223 AFEMMGamgfddvalqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPA 302
Cdd:PRK09050 241 VFRPDG-------------TV-------TAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPA 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 303 PASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDEGPeRVNVNGGAIAMGHPLGATGAMLLGTALDELERRDL 382
Cdd:PRK09050 301 PATRKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLADDDA-RVNPNGGAIALGHPLGMSGARLVLTALHQLERTGG 379
|
410 420
....*....|....*....|..
gi 345112616 383 STALITLCVGGGMGIATIIERV 404
Cdd:PRK09050 380 RYALCTMCIGVGQGIALAIERV 401
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-404 |
1.29e-122 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 360.18 E-value: 1.29e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 1 MAcEAYVFDAIRTPRGRGKttGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWD 80
Cdd:PRK07801 1 MA-EAYIVDAVRTPVGKRK--GGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAGNIARTSWLAAGLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 81 LSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSD---GGPMMLDPAVSMQIGF--------VPQ 149
Cdd:PRK07801 78 EEVPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAmtaGEQLGFTSPFAESKGWlhrygdqeVSQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 150 GIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRDqnglvvLAEDEHIRpDTTLEALAALPPAFEMmG 228
Cdd:PRK07801 158 FRGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNeIVPVGG------VTVDEGPR-ETSLEKMAGLKPLVEG-G 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 229 AMgfddvalqkyvtverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKA 308
Cdd:PRK07801 230 RL--------------------TAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYA 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 309 LQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALIT 388
Cdd:PRK07801 290 LEKTGLSIDDIDVVEINEAFAPVVLAWLKETGAD---PAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQT 366
|
410
....*....|....*.
gi 345112616 389 LCVGGGMGIATIIERV 404
Cdd:PRK07801 367 MCEGGGTANVTIIERL 382
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
4-404 |
2.22e-121 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 357.11 E-value: 2.22e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGrgKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSV 83
Cdd:PRK07850 3 NPVIVEAVRTPIG--KRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSNNITRTAWLHAGLPYHV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGPMMLDP-AVSMQIGFVPQGIGADLIATIEGF 162
Cdd:PRK07850 81 GATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAGPGRGLPrPDSWDIDMPNQFEAAERIAKRRGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 163 TREDVDRYALCSQQRAAHARANGYFKS-----IVPVRDQNG-----LVVLAEDEHIRpDTTLEALAALPPAFEmmgamgf 232
Cdd:PRK07850 161 TREDVDAFGLRSQRRAAQAWAEGRFDReispvQAPVLDEEGqptgeTRLVTRDQGLR-DTTMEGLAGLKPVLE------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 233 ddvalqkyvtveriNHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKA 312
Cdd:PRK07850 233 --------------GGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKA 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 313 GMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVG 392
Cdd:PRK07850 299 GMKIGDIDLVEINEAFASVVLSWAQVHEPD---MDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAG 375
|
410
....*....|..
gi 345112616 393 GGMGIATIIERV 404
Cdd:PRK07850 376 GALSTGTIIERI 387
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
4-404 |
2.03e-117 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 346.95 E-value: 2.03e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKTtGSLYEVKPIDLLTTLFAEL-KRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLS 82
Cdd:PRK08947 3 DVVIVDAIRTPMGRSKG-GAFRNVRAEDLSAHLMRSLlARNPALDPAEIDDIIWGCVQQTLEQGFNIARNAALLAGIPHS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPM--GSDggpmmLDPAVSMQIGFVP--QGIGADLIAT 158
Cdd:PRK08947 82 VPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMnhGVD-----FHPGLSKNVAKAAgmMGLTAEMLGK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 159 IEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVR--DQNG-LVVLAEDEHIRPDTTLEALAALPPAFEMMGAmgfdd 234
Cdd:PRK08947 157 MHGISREQQDAFAARSHQRAWAATQEGRFKNeIIPTEghDADGvLKLFDYDEVIRPETTVEALAALRPAFDPVNG----- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 235 valqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGM 314
Cdd:PRK08947 232 -------TV-------TAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 315 TLDDIDLIEVNEAFAAVVLKFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGG 394
Cdd:PRK08947 298 SISDIDVFELNEAFAAQSLPCLKDLGLLDKMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLG 377
|
410
....*....|
gi 345112616 395 MGIATIIERV 404
Cdd:PRK08947 378 QGIATVFERV 387
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
4-404 |
5.78e-112 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 333.23 E-value: 5.78e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTP--RGRGK--TTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQ---GGniaKTAALY 76
Cdd:PRK06445 3 DVYLVDFARTAfsRFRPKdpQKDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENwlyGG---RHPIFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 77 AGWDLSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSdgGP-------MMLDPAVS---MQIGF 146
Cdd:PRK06445 80 ARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGD--NPhiepnpkLLTDPKYIeydLTTGY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 147 VpQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK-SIVPVRDQ-NGLV-VLAEDEHIRPDTTLEALAALPPA 223
Cdd:PRK06445 158 V-MGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKdEILPIEVEvEGKKkVVDVDQSVRPDTSLEKLAKLPPA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 224 FEMMGamgfddvalqkyvtverinhVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAP 303
Cdd:PRK06445 237 FKPDG--------------------VITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVP 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 304 ASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLS 383
Cdd:PRK06445 297 ASKKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLD---PETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKD 373
|
410 420
....*....|....*....|.
gi 345112616 384 TALITLCVGGGMGIATIIERV 404
Cdd:PRK06445 374 YGVATLCVGGGQGGAVVLERV 394
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
11-404 |
3.01e-110 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 329.26 E-value: 3.01e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 11 IRTPRGRgkTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGnIAKTAALYAGWDLSVPGVQINR 90
Cdd:PRK06205 10 VRTPVGR--FGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPA-IGRVAALDAGLPVTVPGMQLDR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 91 FCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPM-------GSDGGPMMLDPAVS---MQIGFVPQGIGADLIATIE 160
Cdd:PRK06205 87 RCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFyttdmrwGVRGGGVQLHDRLArgrETAGGRRFPVPGGMIETAE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 161 ------GFTREDVDRYALCSQQRAAHARANGYFKS-IVPV--RDQNG-LVVLAEDEHIRPDTTLEALAALPPAfemmgaM 230
Cdd:PRK06205 167 nlrreyGISREEQDALAVRSHQRAVAAQEAGRFDDeIVPVtvPQRKGdPTVVDRDEHPRADTTLESLAKLRPI------M 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 231 GFDDvalqKYVTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQ 310
Cdd:PRK06205 241 GKQD----PEATV-------TAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 311 KAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLC 390
Cdd:PRK06205 310 RAGLTLDDIDLIELNEAFAAQVLAVLKEWGFGADDEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMC 389
|
410
....*....|....
gi 345112616 391 VGGGMGIATIIERV 404
Cdd:PRK06205 390 IGGGQGLAAVFERV 403
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
4-404 |
4.35e-110 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 328.66 E-value: 4.35e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRgkTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSV 83
Cdd:PRK08131 3 DAYIYDGLRSPFGR--HAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP--MG--------------SDGGPMMLDPAVSMQIGFV 147
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPfvMGkaesafsrdakvfdTTIGARFPNPKIVAQYGND 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 148 PQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK-SIVPVRDQNG----LVVLAEDEHIRPDTTLEALAALPP 222
Cdd:PRK08131 161 SMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFAdEITPIEVPQGrklpPKLVAEDEHPRPSSTVEALTKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 223 AFEmmgamgfddvalqkyvtveriNHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPA 302
Cdd:PRK08131 241 LFE---------------------GGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPV 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 303 PASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDEGPeRVNVNGGAIAMGHPLGATGAMLLGTALDELERRDL 382
Cdd:PRK08131 300 EAIKKALARAGLTLDDMDIIEINEAFASQVLGCLKGLGVDFDDP-RVNPNGGAIAVGHPLGASGARLALTAARELQRRGK 378
|
410 420
....*....|....*....|..
gi 345112616 383 STALITLCVGGGMGIATIIERV 404
Cdd:PRK08131 379 RYAVVSLCIGVGQGLAMVIERV 400
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-404 |
2.34e-107 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 321.52 E-value: 2.34e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 1 MACEAYVFDAIRTprGRGKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWD 80
Cdd:PRK09051 1 MMREVVVVSGVRT--AIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMYLSRVAAINAGVP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 81 LSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP-----------MGSDGGPMMLDPAVSMQIGFVPQ 149
Cdd:PRK09051 79 QETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPyllpaarwgarMGDAKLVDMMVGALHDPFGTIHM 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 150 GIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPV--RDQNGLVVLAEDEHIRPDTTLEALAALPPAFEM 226
Cdd:PRK09051 159 GVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDqIVPVeiKTRKGEVVFDTDEHVRADTTLEDLAKLKPVFKK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 227 MGAmgfddvalqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASK 306
Cdd:PRK09051 239 ENG------------TV-------TAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQ 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 307 KALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTAL 386
Cdd:PRK09051 300 KALERAGLTVADLDVIEANEAFAAQACAVTRELGLD---PAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYAL 376
|
410
....*....|....*...
gi 345112616 387 ITLCVGGGMGIATIIERV 404
Cdd:PRK09051 377 VTMCIGGGQGIAAIFERL 394
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
4-404 |
1.61e-106 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 319.64 E-value: 1.61e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKTtGSLYEVKPIDLL-TTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLS 82
Cdd:PRK09052 7 DAYIVAATRTPVGKAPR-GMFKNTRPDDLLaHVLRSAVAQVPGLDPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLPNS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGsdGGPMMLDPA-------VSMQIGFvpqGIGADL 155
Cdd:PRK09052 86 VGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPMM--GNKPSMSPAifardenVGIAYGM---GLTAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 156 IATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVP--VRD-----QNGLVVLAE-----DEHIRPDTTLEALAALPP 222
Cdd:PRK09052 161 VAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDeITPyeITErfpdlATGEVDVKTrtvdlDEGPRADTSLEGLAKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 223 AFEMMGAMgfddvalqkyvtverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPA 302
Cdd:PRK09052 241 VFANKGSV--------------------TAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 303 PASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDL 382
Cdd:PRK09052 301 EAIPAALKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLD---PSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNL 377
|
410 420
....*....|....*....|..
gi 345112616 383 STALITLCVGGGMGIATIIERV 404
Cdd:PRK09052 378 KYGMVTMCVGTGMGAAGIFERL 399
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
4-403 |
8.39e-106 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 318.10 E-value: 8.39e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGR-GKttGSLYEVKPIDLLTTLF-AELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDl 81
Cdd:PRK07851 3 EAVIVSTARSPIGRaFK--GSLKDMRPDDLAAQMVrAALDKVPALDPTDIDDLMLGCGLPGGEQGFNMARVVAVLLGYD- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 82 SVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMG-SDGGPMMLDPAVS------------------- 141
Cdd:PRK07851 80 FLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGnSDSLPDTKNPLFAeaqartaaraeggaeawhd 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 142 -MQIGFVPQ-----GIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYF-KSIVPVRDQNGLVVlAEDEHIRPDTTL 214
Cdd:PRK07851 160 pREDGLLPDvyiamGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFeREITPVTLPDGTVV-STDDGPRAGTTY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 215 EALAALPPAFEMMGamgfddvalqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEP 294
Cdd:PRK07851 239 EKVSQLKPVFRPDG-------------TV-------TAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSP 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 295 TIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTAL 374
Cdd:PRK07851 299 EIMGLGPVEASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGID---EDKLNVSGGAIALGHPFGMTGARITTTLL 375
|
410 420
....*....|....*....|....*....
gi 345112616 375 DELERRDLSTALITLCVGGGMGIATIIER 403
Cdd:PRK07851 376 NNLQTHDKTFGLETMCVGGGQGMAMVLER 404
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-404 |
9.55e-105 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 314.74 E-value: 9.55e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 1 MAcEAYVFDAIRTPRGRgkTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWD 80
Cdd:PRK06504 1 MA-EAYIVAAARTAGGR--KGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNVARNAVLASKLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 81 LSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGS-------DGGPMMLDPAVSMQ---IGFvPQG 150
Cdd:PRK06504 78 ESVPGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSpstlpakNGLGHYKSPGMEERypgIQF-SQF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 151 IGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVP--VRDQNGLVVLAE-DEHIRPDTTLEALAALPPAFEm 226
Cdd:PRK06504 157 TGAEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAeIVPleITRADGSGEMHTvDEGIRFDATLEGIAGVKLIAE- 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 227 mgamgfddvalqkyvtveriNHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASK 306
Cdd:PRK06504 236 --------------------GGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 307 KALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTAL 386
Cdd:PRK06504 296 RALKKAGMKIDDIDLYEVNEAFASVPLAWLKATGAD---PERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGL 372
|
410
....*....|....*...
gi 345112616 387 ITLCVGGGMGIATIIERV 404
Cdd:PRK06504 373 QTMCEGGGMANVTIVERL 390
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
4-404 |
4.27e-101 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 305.52 E-value: 4.27e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGRGKTtGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSV 83
Cdd:PRK07661 3 EAVIVAGARTPVGKAKK-GSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLNMARNIGALAGLPYTV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGsdGGPMMLDPAVSMQIGFVPQGIG--ADLIATIEG 161
Cdd:PRK07661 82 PAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMM--GHVVRPNPRLVEAAPEYYMGMGhtAEQVAVKYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 162 FTREDVDRYALCSQQRAAHARANGYFK-SIVPVR-------DQNGL----VVLAEDEHIRPDTTLEALAALPPAFEMMGA 229
Cdd:PRK07661 160 ISREDQDAFAVRSHQRAAKALAEGKFAdEIVPVDvtlrtvgENNKLqeetITFSQDEGVRADTTLEILGKLRPAFNVKGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 230 MgfddvalqkyvtverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKAL 309
Cdd:PRK07661 240 V--------------------TAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKAL 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 310 QKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITL 389
Cdd:PRK07661 300 KLAGLELSDIGLFELNEAFASQSIQVIRELGLD---EEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTM 376
|
410
....*....|....*
gi 345112616 390 CVGGGMGIATIIERV 404
Cdd:PRK07661 377 CIGGGMGAAGVFELL 391
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
10-403 |
2.99e-91 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 282.42 E-value: 2.99e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 10 AIRTPRGRGKTtGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSVPGVQIN 89
Cdd:PLN02287 53 AYRTPICKAKR-GGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRANECRMAAFYAGFPETVPVRTVN 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 90 RFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGpmmLDPAVSM----QIGFVPQGIGADLIATIEGFTRE 165
Cdd:PLN02287 132 RQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGG---VNPRVESfsqaQDCLLPMGITSENVAERFGVTRE 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 166 DVDRYALCSQQRAAHARANGYFKS-IVPVRDQ--------NGLVVLAEDEHIRPDTTLEALAALPPAFEMMGamgfddva 236
Cdd:PLN02287 209 EQDQAAVESHRKAAAATASGKFKDeIVPVHTKivdpktgeEKPIVISVDDGIRPNTTLADLAKLKPVFKKNG-------- 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 237 lqkyvtverinhVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTL 316
Cdd:PLN02287 281 ------------TTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLEL 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 317 DDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERR--DLSTALITLCVGGG 394
Cdd:PLN02287 349 DDIDLFEINEAFASQFVYCCKKLGLD---PEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRgkDCRFGVVSMCIGTG 425
|
....*....
gi 345112616 395 MGIATIIER 403
Cdd:PLN02287 426 MGAAAVFER 434
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
10-402 |
8.69e-86 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 266.19 E-value: 8.69e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 10 AIRTPRGrgKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSVPGVQIN 89
Cdd:PRK08235 9 AARTPFG--KFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGG-QGQIPSRQAARAAGIPWEVQTETVN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 90 RFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP-----------MGsDGG--PMMLDPAVSMQIGFVPQGIGADLI 156
Cdd:PRK08235 86 KVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPyilpgarwgyrMG-DNEviDLMVADGLTCAFSGVHMGVYGGEV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 157 ATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRDQN---GLVVLAEDEHIRPDTTLEALAALPPAFEMMGAMgf 232
Cdd:PRK08235 165 AKELGISREAQDEWAYRSHQRAVSAHEEGRFEEeIVPVTIPQrkgDPIVVAKDEAPRKDTTIEKLAKLKPVFDKTGTI-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 233 ddvalqkyvtverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKA 312
Cdd:PRK08235 243 ------------------TAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 313 GMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVG 392
Cdd:PRK08235 305 GKTVEDIDLFEINEAFAAVALASTEIAGID---PEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSG 381
|
410
....*....|
gi 345112616 393 GGMGIATIIE 402
Cdd:PRK08235 382 GGQGDAVLIE 391
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
6-404 |
1.55e-85 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 266.88 E-value: 1.55e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 6 YVFDAIRTP--RGRGKTTgslyEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEQGgNIAKTAALYAGWDLSV 83
Cdd:PRK08170 6 YIVDGARTPflKARGGPG----PFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEA-NIARVVALRLGCGEKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP--------------MGSDGG-----------PMMLDP 138
Cdd:PRK08170 81 PAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPllfsekmvrwlagwYAAKSIgqklaalgklrPSYLAP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 139 AVSMQIGF----VPQGIG--ADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKSIVPVRDQNGlVVLAEDEHIRPDT 212
Cdd:PRK08170 161 VIGLLRGLtdpvVGLNMGqtAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLKEVVPLFDRDG-KFYDHDDGVRPDS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 213 TLEALAALPPAFEmmgamgfddvalQKYVTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGT 292
Cdd:PRK08170 240 SMEKLAKLKPFFD------------RPYGRV-------TAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAAL 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 293 EPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVL---------KFMRDM-GLEDE----GPERVNVNGGAIAM 358
Cdd:PRK08170 301 DPSQMGLGPVHAATPLLQRHGLTLEDLDLWEINEAFAAQVLaclaawadeEYCREQlGLDGAlgelDRERLNVDGGAIAL 380
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 345112616 359 GHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATIIERV 404
Cdd:PRK08170 381 GHPVGASGARIVLHLLHALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
1-404 |
1.57e-82 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 258.04 E-value: 1.57e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 1 MACEAYVFDAIRTprGRGKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTpIGEQGGNIAKTAALYAGWD 80
Cdd:PRK06633 1 MTKPVYITHAKRT--AFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVI-TGGSGQNPARQTLIHAGIP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 81 LSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMS------RVPMGSDGGP------MMLDPAVSMQIGfVP 148
Cdd:PRK06633 78 KEVPGYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSlgmhgsYIRAGAKFGDikmvdlMQYDGLTDVFSG-VF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 149 QGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK-SIVPVR--DQNGLVVLAEDEHIRPDTTLEALAALPPAFE 225
Cdd:PRK06633 157 MGITAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKdEILPIEvtIKKTTSLFDHDETVRPDTSLEILSKLRPAFD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 226 MmgamgfddvalqkyvtveriNHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPAS 305
Cdd:PRK06633 237 K--------------------NGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPAS 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 306 KKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTA 385
Cdd:PRK06633 297 QKALSKAGWSVNDLEVIEVNEAFAAQSIYVNREMKWD---MEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKG 373
|
410
....*....|....*....
gi 345112616 386 LITLCVGGGMGIATIIERV 404
Cdd:PRK06633 374 LVTLCIGGGMGMAMCVEAV 392
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
43-402 |
1.37e-79 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 250.46 E-value: 1.37e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 43 RHELDTSQVDDVILGCVTPIGEQGGNIAKTAALYAGWDLSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESM 122
Cdd:PRK07108 41 RAKLDPAEVEDVIMGCANPEGATGANIARQIALRAGLPVTVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 123 SRVP------MGSDGGPMMLDPAVSMqigfvPQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRD 195
Cdd:PRK07108 121 SCVQnemnrhMLREGWLVEHKPEIYW-----SMLQTAENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDeIVPITV 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 196 QNGL------------VVLAEDEHIRPDTTLEALAALPPAFEmmgamgfddvalqkyvtveriNHVHTAGNSSGIVDGAA 263
Cdd:PRK07108 196 TAGVadkatgrlftkeVTVSADEGIRPDTTLEGVSKIRSALP---------------------GGVITAGNASQFSDGAS 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 264 LVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEd 343
Cdd:PRK07108 255 ACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDLWELNEAFAVQVLYCRDTLGIP- 333
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 345112616 344 egPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATIIE 402
Cdd:PRK07108 334 --MDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAAGLFE 390
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
18-403 |
1.53e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 250.19 E-value: 1.53e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 18 GKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSVPGVQINRFCASGLD 97
Cdd:PRK05656 15 GSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAG-AGQNPARQAAIKAGLPHSVPAMTLNKVCGSGLK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 98 AVNLAAMKVRSGWEDLVVAGGVESMSRVPM---GSDGGPMM-----LDPAVS--MQIGF--VPQGIGADLIATIEGFTRE 165
Cdd:PRK05656 94 ALHLAAQAIRCGDAEVIIAGGQENMSLAPYvlpGARTGLRMghaqlVDSMITdgLWDAFndYHMGITAENLVEKYGISRE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 166 DVDRYALCSQQRAAHARANGYFKS-IVPV---RDQNGLVVLAEDEHIRPDTTLEALAALPPAFEMMGAMgfddvalqkyv 241
Cdd:PRK05656 174 AQDAFAAASQQKAVAAIEAGRFDDeITPIlipQRKGEPLAFATDEQPRAGTTAESLAKLKPAFKKDGSV----------- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 242 tverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDL 321
Cdd:PRK05656 243 ---------TAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 322 IEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATII 401
Cdd:PRK05656 314 IEANEAFAAQSLAVGKELGWD---AAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAI 390
|
..
gi 345112616 402 ER 403
Cdd:PRK05656 391 ER 392
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
4-404 |
2.28e-76 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 240.82 E-value: 2.28e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGrgKTTGSLYEVKPIDLLTTLFAELKRRHEldtSQVDDVILGCVTpigEQGGNIAKTAALYAGWDLSV 83
Cdd:PRK06690 2 RAVIVEAKRTPIG--KKNGMLKDYEVQQLAAPLLTFLSKGME---REIDDVILGNVV---GPGGNVARLSALEAGLGLHI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 84 PGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGgpmMLDPAVsmqIGFVPQGIGADLIATIEGFT 163
Cdd:PRK06690 74 PGVTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQNRA---RFSPET---IGDPDMGVAAEYVAERYNIT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 164 REDVDRYALCSQQRAAHARANGYFK-SIVPVrdqNGLvvlaEDEHIRPDTTLEAL-AALPPAFEMMGAMgfddvalqkyv 241
Cdd:PRK06690 148 REMQDEYACLSYKRTLQALEKGYIHeEILSF---NGL----LDESIKKEMNYERIiKRTKPAFLHNGTV----------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 242 tverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDL 321
Cdd:PRK06690 210 ---------TAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDY 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 322 IEVNEAFAAVVLKFMRDMGLEDegpERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATII 401
Cdd:PRK06690 281 FEINEAFASKVVACAKELQIPY---EKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLF 357
|
...
gi 345112616 402 ERV 404
Cdd:PRK06690 358 EKV 360
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
10-404 |
1.34e-66 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 216.88 E-value: 1.34e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 10 AIRTPRGrgKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSVPGVQIN 89
Cdd:PLN02644 8 VARTPIG--GFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSAN-LGQAPARQAALGAGLPPSTICTTVN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 90 RFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPM---GSDGGPMMLDPAVS---MQIGF------VPQGIGADLIA 157
Cdd:PLN02644 85 KVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKylpEARKGSRLGHDTVVdgmLKDGLwdvyndFGMGVCAELCA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 158 TIEGFTREDVDRYALCSQQRAAHARANGYFK-SIVPVRDQNG----LVVLAEDEHI-RPDttLEALAALPPAFEMMGAmg 231
Cdd:PLN02644 165 DQYSISREEQDAYAIQSYERAIAAQEAGAFAwEIVPVEVPGGrgrpSVIVDKDEGLgKFD--PAKLRKLRPSFKEDGG-- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 232 fddvalqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQK 311
Cdd:PLN02644 241 ----------SV-------TAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKH 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 312 AGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCV 391
Cdd:PLN02644 304 AGLEASQVDYYEINEAFSVVALANQKLLGLD---PEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICN 380
|
410
....*....|...
gi 345112616 392 GGGMGIATIIERV 404
Cdd:PLN02644 381 GGGGASAIVVELM 393
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
7-403 |
4.00e-66 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 216.39 E-value: 4.00e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 7 VFDAIRTPRGRGKTtgSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEqGGNIAKTAALYAGWDLSVPGV 86
Cdd:PRK08963 9 IVSGLRTPFAKQAT--AFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPE-APNIAREIVLGTGMNVHTDAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 87 QINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMG-------------------------SDGGP---MMLDP 138
Cdd:PRK08963 86 SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGvskklaralvdlnkartlgqrlklfSRLRLrdlLPVPP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 139 AVSMQIGFVPQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK-----SIVPVRDQnglvVLAEDEHIRPDTT 213
Cdd:PRK08963 166 AVAEYSTGLRMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDdevmtAHVPPYKQ----PLEEDNNIRGDST 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 214 LEALAALPPAFEmmgamgfddvalQKYVTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTE 293
Cdd:PRK08963 242 LEDYAKLRPAFD------------RKHGTV-------TAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAID 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 294 PTI-MLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVL--------------KFMRDMGLEDEGPERVNVNGGAIAM 358
Cdd:PRK08963 303 VWQdMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaserfareKLGRSQAIGEVDMSKFNVLGGSIAY 382
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 345112616 359 GHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATIIER 403
Cdd:PRK08963 383 GHPFAATGARMITQTLHELRRRGGGLGLTTACAAGGLGAAMVLEV 427
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
4-404 |
2.25e-63 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 208.33 E-value: 2.25e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 4 EAYVFDAIRTPRGR-GKttgSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLS 82
Cdd:PRK06366 3 DVYIVSAKRTAIGKfGR---SFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAG-VGQNPAGQAAYHAGLPFG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVP--MGSD--GGP------------MMLDPAVSMQIGF 146
Cdd:PRK06366 79 VTKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPflLPSDlrWGPkhllhknykiddAMLVDGLIDAFYF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 147 VPQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYF-KSIVPVRDqnglvvLAEDEHIRpDTTLEALAALPPAFE 225
Cdd:PRK06366 159 EHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFrNEIVPFND------LDRDEGIR-KTTMEDLAKLPPAFD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 226 MMGAMgfddvalqkyvtverinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPAS 305
Cdd:PRK06366 232 KNGIL--------------------TAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPAT 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 306 KKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDegpERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTA 385
Cdd:PRK06366 292 RKLLEKQNKSIDYYDLVEHNEAFSIASIIVRDQLKIDN---ERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTG 368
|
410
....*....|....*....
gi 345112616 386 LITLCVGGGMGIATIIERV 404
Cdd:PRK06366 369 LATLCHGGGGAHTLTLEMV 387
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
6-271 |
1.56e-54 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 181.35 E-value: 1.56e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 6 YVFDAIRTPRGRGKttGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPiGEQGGNIAKTAALYAGWDLSVPG 85
Cdd:pfam00108 2 VIVSAARTPFGSFG--GSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQ-AGEGQNPARQAALKAGIPDSAPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 86 VQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDGGP-------------MMLDPAVSMQIGFVPQGIG 152
Cdd:pfam00108 79 VTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDArsglkhgdekkhdLLIPDGLTDAFNGYHMGLT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 153 ADLIATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVR--DQNGLVVLAEDEHIRPDTTLEALAALPPAFemmga 229
Cdd:pfam00108 159 AENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDeIVPVTvkGRKGKPTVDKDEGIRPPTTAEPLAKLKPAF----- 233
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 345112616 230 mgfddvalQKYVTVerinhvhTAGNSSGIVDGAALVLIGSKE 271
Cdd:pfam00108 234 --------DKEGTV-------TAGNASPINDGAAAVLLMSES 260
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
43-402 |
4.33e-54 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 184.33 E-value: 4.33e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 43 RHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGWDLSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESM 122
Cdd:PRK06954 45 RAGLKPEQIDEVVMGCVLPAG-QGQAPARQAALGAGLPLSVGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESM 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 123 SRVPM---GSDGG----------PMMLDPAVSMQIGFVPQGIGADLIATIEGFTREDVDRYALCSQQRAAHARANGYFK- 188
Cdd:PRK06954 124 TNAPYllpKARGGmrmghgqvldHMFLDGLEDAYDKGRLMGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAw 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 189 SIVPVR--DQNGLVVLAEDEHIRpDTTLEALAALPPAFEMMGAMgfddvalqkyvtverinhvhTAGNSSGIVDGAALVL 266
Cdd:PRK06954 204 EIAPVTvaGKKGDTVIDRDEQPF-KANPEKIPTLKPAFSKTGTV--------------------TAANSSSISDGAAALV 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 267 IGSKEKGEALGLKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDegp 346
Cdd:PRK06954 263 MMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEINEAFAVVTMAAMKEHGLPH--- 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 345112616 347 ERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATIIE 402
Cdd:PRK06954 340 EKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIE 395
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
18-402 |
3.64e-51 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 176.53 E-value: 3.64e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 18 GKTTGSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGCVTPIGEqGGNIAKTAALYAGWDLSVPGVQINRFCASGLD 97
Cdd:cd00826 12 GGENGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGE-GQNCAQQAAMHAGGLQEAPAIGMNNLCGSGLR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 98 AVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSdggpmmldpAVSMQIGFVPQGIGadliatiegfTREDVDRYALCSQQR 177
Cdd:cd00826 91 ALALAMQLIAGGDANCILAGGFEKMETSAENN---------AKEKHIDVLINKYG----------MRACPDAFALAGQAG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 178 AAHARANGYFKS-IVP--VRDQNGLVVLAEDEHIR--PDTTLEALAALPPAFEMMGAMgfddvalqkyvtverinhvhTA 252
Cdd:cd00826 152 AEAAEKDGRFKDeFAKfgVKGRKGDIHSDADEYIQfgDEASLDEIAKLRPAFDKEDFL--------------------TA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 253 GNSSGIVDGAALVLIGSKE-------KGEALGLKPRARIISAALVGTEPT----IMLTGPAPASKKALQKAGMTLDDIDL 321
Cdd:cd00826 212 GNACGLNDGAAAAILMSEAeaqkhglQSKAREIQALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 322 IEVNEAFAAVVLKFMRDMGLEDEGPER---------------VNVNGGAIAMGHPLGATGAMLLGTALDELERRDLSTA- 385
Cdd:cd00826 292 IEAHDAFAANACATNEALGLCPEGQGGalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQg 371
|
410 420
....*....|....*....|.
gi 345112616 386 ----LITLCVGGGMGIATIIE 402
Cdd:cd00826 372 agagLALLCIGGGGGAAMCIE 392
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
278-403 |
7.06e-51 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 167.05 E-value: 7.06e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 278 LKPRARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEdegPERVNVNGGAIA 357
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGID---PEKVNVNGGAIA 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 345112616 358 MGHPLGATGAMLLGTALDELERRDLSTALITLCVGGGMGIATIIER 403
Cdd:pfam02803 78 LGHPLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
31-403 |
7.48e-48 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 168.54 E-value: 7.48e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 31 DLLTTLFAELKRRHELDTSQVDDVILGCVTPiGEQGGNIAKTAALYAGWDLSVPGVQINRFCASGLDAVNLAAMKVRSGW 110
Cdd:PRK09268 33 DMLTAALDGLVDRFGLQGERLGEVVAGAVLK-HSRDFNLTRECVLGSALSPYTPAYDLQQACGTGLEAAILVANKIALGQ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 111 EDLVVAGGVESMSRVPMG-SDG------------------------GPMMLDPAV----------SMqigfvpqGIGADL 155
Cdd:PRK09268 112 IDSGIAGGVDTTSDAPIAvNEGlrkillelnrakttgdrlkalgklRPKHLAPEIprngeprtglSM-------GEHAAI 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 156 IATIEGFTREDVDRYALCSQQRAAHARANGYFKS-IVPVRDqnglvvLAEDEHIRPDTTLEALAALPPAFemmgamGFDD 234
Cdd:PRK09268 185 TAKEWGISREAQDELAAASHQNLAAAYDRGFFDDlITPFLG------LTRDNNLRPDSSLEKLAKLKPVF------GKGG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 235 VAlqkyvTVerinhvhTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISA--ALV----GTEPtiMLTGPAPASKKA 308
Cdd:PRK09268 253 RA-----TM-------TAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAetAAVdfvhGKEG--LLMAPAYAVPRL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 309 LQKAGMTLDDIDLIEVNEAFAAVVL---------KFMRD-MGLEdeGP------ERVNVNGGAIAMGHPLGATGAMLLGT 372
Cdd:PRK09268 319 LARNGLTLQDFDFYEIHEAFASQVLatlkawedeEYCRErLGLD--APlgsidrSKLNVNGSSLAAGHPFAATGGRIVAT 396
|
410 420 430
....*....|....*....|....*....|.
gi 345112616 373 ALDELERRDLSTALITLCVGGGMGIATIIER 403
Cdd:PRK09268 397 LAKLLAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
252-401 |
8.42e-23 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 96.36 E-value: 8.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 252 AGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPT----IMLTGPAPASKKALQKAGMTLDDIDLIEVNEA 327
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 328 FAAVVLKFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGAMLLGTALDELERRDLS-------TALITLCVGGGMGIATI 400
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVRSPAVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPptpreprTVLLLGFGLGGTNAAVV 253
|
.
gi 345112616 401 I 401
Cdd:cd00327 254 L 254
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
46-377 |
1.43e-20 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 92.33 E-value: 1.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 46 LDTSQVDDVILGCVTPiGEQGGNIAKTAALYAGwDLSVPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRV 125
Cdd:cd00829 33 LEPADIDAVVVGNAAG-GRFQSFPGALIAEYLG-LLGKPATRVEAAGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 126 PMGSDGGPMMLDPAVSMQI---GFVPQGIGAdLIAT--IE--GFTREDVDRYALcsQQRAaHARANGYfksivpvrdqng 198
Cdd:cd00829 111 PTGDEAGGRASDLEWEGPEppgGLTPPALYA-LAARryMHryGTTREDLAKVAV--KNHR-NAARNPY------------ 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 199 lvvlAedeHIRPDTTLEALAALPPAFEMMGAMgfddvalqkyvtverinhvhtagNSSGIVDGAALVLIGSKEKGEALGL 278
Cdd:cd00829 175 ----A---QFRKPITVEDVLNSRMIADPLRLL-----------------------DCCPVSDGAAAVVLASEERARELTD 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 279 KPrARIISAALVGTEPTIM-------LTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGL--EDEGPER- 348
Cdd:cd00829 225 RP-VWILGVGAASDTPSLSerddflsLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFceKGEGGKLv 303
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 345112616 349 ------------VNVNGGAIAMGHPLGATGAMLLGTALDEL 377
Cdd:cd00829 304 regdtaiggdlpVNTSGGLLSKGHPLGATGLAQAVEAVRQL 344
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
68-366 |
6.32e-14 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 72.62 E-value: 6.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 68 NIAKTAALYAGwdLS-VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPmGSDGGPMM---LDPAVSMQ 143
Cdd:PRK06064 62 HIAALIADYAG--LApIPATRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTDVP-TPDATEAIaraGDYEWEEF 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 144 IGFVPQGIGAdLIATIE----GFTREDvdryaLCsqQRAAHARANGyfksivpvrdqnglvVLAEDEHIRPDTTLEALAA 219
Cdd:PRK06064 139 FGATFPGLYA-LIARRYmhkyGTTEED-----LA--LVAVKNHYNG---------------SKNPYAQFQKEITVEQVLN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 220 LPPafemmgamgfddVA--LQKYvtverinhvhtagNSSGIVDGAALVLIGSKEKGEALGLKPrARIIS-------AALV 290
Cdd:PRK06064 196 SPP------------VAdpLKLL-------------DCSPITDGAAAVILASEEKAKEYTDTP-VWIKAsgqasdtIALH 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 291 GTEPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMG---------LEDEGPER------VNVNGGA 355
Cdd:PRK06064 250 DRKDFTTLDAAVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAYEDLGfakkgeggkLAREGQTYiggdipVNPSGGL 329
|
330
....*....|.
gi 345112616 356 IAMGHPLGATG 366
Cdd:PRK06064 330 KAKGHPVGATG 340
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
22-366 |
1.14e-10 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 62.74 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 22 GSLYEVKPIDLLTTLFAELKRRHELDTSQVDDVILGcvTPIGEQGGNIAKTAALYAgwdLSVPGVQINR---FCASGLDA 98
Cdd:PRK06157 20 GERWDAGAEDLMVEAFLEALADAGIEPKDIDAAWFG--THYDEIGSGKSGTPLSRA---LRLPNIPVTRvenFCATGSEA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 99 VNLAAMKVRSGWEDLVVAGGVESM-----SRVPMGSDGGPM-MLDPAVSMQIGFvpqGIGADLIATIEGFTREDVDRyAL 172
Cdd:PRK06157 95 FRGAVYAVASGAYDIALALGVEKLkdtgyGGLPVANPGTLAdMTMPNVTAPGNF---AQLASAYAAKYGVSREDLKR-AM 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 173 CsqQRAAHARANGyfksivpvrdqnglvVLAEDEHIRPDTTLEALAALPPAFEMMGAMgfddvalqkyvtverinhvhta 252
Cdd:PRK06157 171 A--HVSVKSHANG---------------ARNPKAHLRKAVTEEQVLKAPMIAGPLGLF---------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 253 gNSSGIVDGAALVLIGSKEKGEALGlKPRARIISAALVGTEPTIMLTGPA----------PASKKALQKAGMT--LDDID 320
Cdd:PRK06157 212 -DCCGVSDGAAAAIVTTPEIARALG-KKDPVYVKALQLAVSNGWELQYNGwdgsyfpttrIAARKAYREAGITdpREELS 289
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 345112616 321 LIEVNEAFAAVVLKFMRDMGLEDEG-----------------PerVNVNGGAIAMGHPLGATG 366
Cdd:PRK06157 290 MAEVHDCFSITELVTMEDLGLSERGqawrdvldgffdadgglP--CQIDGGLKCFGHPIGASG 350
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
76-366 |
1.73e-09 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 59.09 E-value: 1.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 76 YAGWDLSVPgVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVpmgsdggpmmlDPAVSMQIGfvpqGIGADL 155
Cdd:PRK12578 67 YSGLTGKVP-LRVEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKMTEV-----------DTSTSLAIG----GRGGNY 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 156 IATIEGFTREDVDRYALCSqqrAAHARANGyfksivpvrdqnglvvlaedehirpdTTLEALAALPPAFEMMGAMGfDDV 235
Cdd:PRK12578 131 QWEYHFYGTTFPTYYALYA---TRHMAVYG--------------------------TTEEQMALVSVKAHKYGAMN-PKA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 236 ALQKYVTVER------INHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIIS-------AALVGTEPTIMLTGPA 302
Cdd:PRK12578 181 HFQKPVTVEEvlksraISWPIKLLDSCPISDGSATAIFASEEKVKELKIDSPVWITGigyandyAYVARRGEWVGFKATQ 260
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 345112616 303 PASKKALQKAGMTLDDIDLIEVNEAFAAVVL---------------KFMRDMGLEDEGPERVNVNGGAIAMGHPLGATG 366
Cdd:PRK12578 261 LAARQAYNMAKVTPNDIEVATVHDAFTIAEImgyedlgftekgkggKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATG 339
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
62-366 |
3.00e-09 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 58.37 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 62 IGEQGGNIAKTAALYAgwdlsvPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPmGSDGGPMMLDPAvs 141
Cdd:PTZ00455 96 VGSLGQSGASNALLYK------PAMRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEVQTTVS-ARVGGDYLARAA-- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 142 mqiGFVPQGIGADL------------IATIEGFTREDVDRYAlcsqqraAHARANGyfksivpvrDQNGLVVLaedeHIR 209
Cdd:PTZ00455 167 ---DYRRQRKLDDFtfpclfakrmkyIQEHGHFTMEDTARVA-------AKAYANG---------NKNPLAHM----HTR 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 210 PDTTLEALAALPPAFEMMGAmgfddvalqkyvtvERINHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPR-ARII--- 285
Cdd:PTZ00455 224 KLSLEFCTGASDKNPKFLGN--------------ETYKPFLRMTDCSQVSDGGAGLVLASEEGLQKMGLSPNdSRLVeik 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 286 -SAALVGT------EPTIMLTGPApASKKALQKAGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDEGPER---------- 348
Cdd:PTZ00455 290 sLACASGNlyedppDATRMFTSRA-AAQKALSMAGVKPSDLQVAEVHDCFTIAELLMYEALGIAEYGHAKdlirngatal 368
|
330 340
....*....|....*....|...
gi 345112616 349 -----VNVNGGAIAMGHPLGATG 366
Cdd:PTZ00455 369 egripVNTGGGLLSFGHPVGATG 391
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
256-404 |
3.89e-09 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 58.03 E-value: 3.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 256 SGIVDGAALVLIGSKEKGEALglkPRA-RIISAALVGT-------EPTIMlTGPAPASKKALQKAGMTLDDIDLIEVNEA 327
Cdd:PRK07516 213 SLVSDGAAALVLADAETARAL---QRAvRFRARAHVNDflplsrrDPLAF-EGPRRAWQRALAQAGVTLDDLSFVETHDC 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 328 FAAVVLKFMRDMGLE---------DEGPER------VNVNGGAIAMGHPLGATG-------AM-LLGTAlDELERRDLST 384
Cdd:PRK07516 289 FTIAELIEYEAMGLAppgqgaraiREGWTAkdgklpVNPSGGLKAKGHPIGATGvsmhvlaAMqLTGEA-GGMQIPGAKL 367
|
170 180
....*....|....*....|...
gi 345112616 385 ALITLCvgGGMGIA---TIIERV 404
Cdd:PRK07516 368 AGVFNM--GGAAVAnyvSILERV 388
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
83-366 |
2.47e-07 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 52.21 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 83 VPGVQINRFCASGLDAVNLAAMKVRSGWEDLVVAGGVESMSRVPMGSDG----GPMM-LDPAVSMQIGFVPQGIGADLIA 157
Cdd:PRK08256 71 IPIVNVNNNCSTGSTALFLARQAVRSGAADCALALGFEQMQPGALGSVWddrpSPLErFDKALAELQGFDPAPPALRMFG 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 158 tieGFTREDVDRYALCSQQRAA-------HARANGY--FKSIVPVRDqnglvVLAEDEHIRPDTTLEALaalPPAfemmg 228
Cdd:PRK08256 151 ---GAGREHMEKYGTTAETFAKigvkarrHAANNPYaqFRDEYTLED-----VLASPMIWGPLTRLQCC---PPT----- 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 229 amgfddvalqkyvtverinhvhtagnssgivDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPT-------IMLTGp 301
Cdd:PRK08256 215 -------------------------------CGAAAAIVCSEEFARKHGLDRAVEIVAQAMTTDTPStfdgrsmIDLVG- 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 302 APASKKALQK----AGMTLDDIDLIEVNEAFAAVVLKFMRDMGLEDEG-PER--------------VNVNGGAIAMGHPL 362
Cdd:PRK08256 263 YDMTRAAAQQvyeqAGIGPEDIDVVELHDCFSANELLTYEALGLCPEGeAEKfiddgdntyggrwvVNPSGGLLSKGHPL 342
|
....
gi 345112616 363 GATG 366
Cdd:PRK08256 343 GATG 346
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
256-370 |
1.07e-06 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 50.46 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 256 SGIVDGAALVLIGSKEKGEALGLK-PRARII----SAALVGTEPTIMLTGPAP--------ASKKALQKAGMTLDDIDLI 322
Cdd:PRK06289 220 SQVTDGGAGVVLASDAYLRDYADArPIPRIKgwghRTAPLGLEQKLDRSAGDPyvlphvrqAVLDAYRRAGVGLDDLDGF 299
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 345112616 323 EVNEAFAAVVL---------------KFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGA-MLL 370
Cdd:PRK06289 300 EVHDCFTPSEYlaidhigltgpgeswKAIENGEIAIGGRLPINPSGGLIGGGHPVGASGVrMLL 363
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
304-380 |
1.77e-06 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 49.91 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 304 ASKKALQKAGMT--LDDIDLIEVNEAFAAVVLKFMRDMGL---------------EDEGPERVNVNGGAIAMGHPLGATG 366
Cdd:PRK06365 298 AAKEAYEMAGITdpLNDLDLIELHDAYTSSEIQTYEDLGLckygeggqfiesgkpELPGKLPVNPSGGLLAAGHAVGATG 377
|
90
....*....|....
gi 345112616 367 AMLLGTALDELERR 380
Cdd:PRK06365 378 IMQAVFMFWQLQGR 391
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
260-392 |
2.38e-05 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 46.20 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 260 DGAALVLIGSKEKGEALGLKPRARIISAALV-----GTEPTIMLTGPAPASKKALQKAGMTLDDIDLI-------EVNEA 327
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGFGLTcdayhMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIhahgtatRLNDQ 289
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 345112616 328 FAAVVLK--FmrdmgledegPERVNVNGGAIAMGHPLGATGAMllGTALDELErrdLSTALITLCVG 392
Cdd:PRK05952 290 REANLIQalF----------PHRVAVSSTKGATGHTLGASGAL--GVAFSLLA---LRHQQLPPCVG 341
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
42-171 |
2.92e-05 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 45.50 E-value: 2.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 42 RRHELDTSQVDDVILGCVTPIGeQGGNIAKTAALYAGwDLSVPGVQINRFCASGLDAVNLAAMKVRSG-WED-LVVAGGV 119
Cdd:cd00827 61 ERAGIDPDDIGLLIVATESPID-KGKSAATYLAELLG-LTNAEAFDLKQACYGGTAALQLAANLVESGpWRYaLVVASDI 138
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 345112616 120 eSMSRVPMGSDGGPMMLDPAVSMQIGFVPQGIGADLIATIEGFTREDVDRYA 171
Cdd:cd00827 139 -ASYLLDEGSALEPTLGDGAAAMLVSRNPGILAAGIVSTHSTSDPGYDFSPY 189
|
|
| decarbox_cond_enzymes |
cd00825 |
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ... |
245-378 |
1.38e-04 |
|
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).
Pssm-ID: 238421 [Multi-domain] Cd Length: 332 Bit Score: 43.39 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 245 RINHVHTAGNSSGIVDGAALVLIGSKEKGEALGLKPRARIISAALVGTEPTIMLTGP-----APASKKALQKAGMTLDDI 319
Cdd:cd00825 146 ASRTFDAAADGFVFGDGAGALVVEELEHALARGAHIYAEIVGTAATIDGAGMGAFAPsaeglARAAKEALAVAGLTVWDI 225
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 345112616 320 DLIEVNEAFAAVVLKFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGAMLLGTALDELE 378
Cdd:cd00825 226 DYLVAHGTGTPIGDVKELKLLRSEFGDKSPAVSATKAMTGNLSSAAVVLAVDEAVLMLE 284
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
92-133 |
2.06e-03 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 39.54 E-value: 2.06e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 345112616 92 CASGLDAVNLAAMKVRSGWEDLVVAGGVESM---------SRVPMGSDGGP 133
Cdd:pfam00109 173 CSSSLVAIHAAVQSIRSGEADVALAGGVNLLltplgfagfSAAGMLSPDGP 223
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
256-377 |
2.26e-03 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 39.73 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 256 SGIVDGAALVLIGSKEKGEALGLKPRarIISAALVGTEPTIMLT---GPAP----ASKKALQKAGMT--LDDIDLIEVNE 326
Cdd:PRK06066 208 APFVDGAIVVVLASEEVAKKLTDDPV--WIKGIGWSTESSNLETaelGKANymriAADMAYKMAGIEspRKEVDAAEVDD 285
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 345112616 327 AFA---------------AVVLKFMRDMGLEDEGPERVNVNGGAIAMGHPLGATGAMLLGTALDEL 377
Cdd:PRK06066 286 RYSykelqhiealrlseePEKDSLLREGNFDPQGELPVNPSGGHLAKGVPLEASGLSLLLDAVEYL 351
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
92-123 |
2.41e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 39.83 E-value: 2.41e-03
10 20 30
....*....|....*....|....*....|..
gi 345112616 92 CASGLDAVNLAAMKVRSGWEDLVVAGGVESMS 123
Cdd:cd00834 161 CASGAHAIGDAARLIRLGRADVVIAGGAEALI 192
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
260-367 |
4.70e-03 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 39.00 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 260 DGAALVLIGSKEKGEALGLKPRARIISAALVG-----TEPTIMLTGPAPASKKALQKAGMTLDDIDLI----------EV 324
Cdd:PRK07314 232 EGAGILVLEELEHAKARGAKIYAEVVGYGMTGdayhmTAPAPDGEGAARAMKLALKDAGINPEDIDYInahgtstpagDK 311
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 345112616 325 NEAfAAVVLKFmrdmgleDEGPERVNVNGGAIAMGHPLGATGA 367
Cdd:PRK07314 312 AET-QAIKRVF-------GEHAYKVAVSSTKSMTGHLLGAAGA 346
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
258-394 |
6.39e-03 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 38.47 E-value: 6.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 258 IVDGAALVLIGSKEKGEALGLKP-----RARIISAALVGTEPTIMLTGPAPASKKALQKAGMTLDDIDLIEVNEAFAAVV 332
Cdd:PRK06158 208 VTDGAGAVVMVRADRARDLPRPPvyvlgAAAATWHRQISSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTINT 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 333 LKFMRDMGL--EDEG---------------PerVNVNGGAIAMGHPlGATGAMLLGTALDELE----RRDLSTALITLCV 391
Cdd:PRK06158 288 ILFLEDLGFcaKGEGgafveggriapggrlP--VNTNGGGLSCVHP-GMYGLFLLIEAVRQLRgeagERQVAGAEVALAH 364
|
...
gi 345112616 392 GGG 394
Cdd:PRK06158 365 GNG 367
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
256-368 |
9.05e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 37.90 E-value: 9.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 256 SGIV--DGAALVLIGSKEKGEALGLKPRARIISAALVG-----TEPTIMLTGPAPASKKALQKAGMTLDDIDLI------ 322
Cdd:cd00834 225 DGFVlgEGAGVLVLESLEHAKARGAKIYAEILGYGASSdayhiTAPDPDGEGAARAMRAALADAGLSPEDIDYInahgts 304
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 345112616 323 ----EVNEAFAavvlkfMRDMGLEDEGPERVNVNGGAIamGHPLGATGAM 368
Cdd:cd00834 305 tplnDAAESKA------IKRVFGEHAKKVPVSSTKSMT--GHLLGAAGAV 346
|
|
| PRK08257 |
PRK08257 |
acetyl-CoA acetyltransferase; Validated |
259-354 |
9.40e-03 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 236204 [Multi-domain] Cd Length: 498 Bit Score: 37.97 E-value: 9.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 345112616 259 VDGAALVLIGSKEKGEALGLkPRARII----SAALVgtEPTIMLTGPAPAS--------KKALQKAGMTLDDIDLIEVNE 326
Cdd:PRK08257 243 VDQGAAVLLTSVAKARRLGV-PEDRWVylhgGADAH--DPYDILERPDLHRspairaagRRALALAGLGIDDIDAFDLYS 319
|
90 100
....*....|....*....|....*...
gi 345112616 327 AFAAVVLKFMRDMGLEDEGPERVNVNGG 354
Cdd:PRK08257 320 CFPSAVQVAARELGLDLDDPRPLTVTGG 347
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
92-122 |
9.81e-03 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 37.77 E-value: 9.81e-03
10 20 30
....*....|....*....|....*....|.
gi 345112616 92 CASGLDAVNLAAMKVRSGWEDLVVAGGVESM 122
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAA 191
|
|
| |
