|
Name |
Accession |
Description |
Interval |
E-value |
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
81-1479 |
0e+00 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 2225.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 81 PKFDSKYWIKNLKALYQSDPDYFKPNKLGVAFRDLRAYGIANDFDYQTTVATGLIKFVVDGSRYFRKDDKSRYFDILKPM 160
Cdd:TIGR00956 1 EEFNAKAWVKNFRKLIDSDPIYYKPYKLGVAYKNLSAYGVAADSDYQPTFPNALLKILTRGFRKLKKFRDTKTFDILKPM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 161 DGLLRPGELTVVLGRPGAGCSTLLKTLAVNTYGFQVDKDSKVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLE 240
Cdd:TIGR00956 81 DGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIGVEGVITYDGITPEEIKKHYRGDVVYNAETDVHFPHLTVGETLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 241 FAARLRTPQNRGLGVDRETYAKHMASVYMATYGILRQRNTPVGNEFVPGCSGGERKRVSIAEVSLSGANIQCWDNATRGL 320
Cdd:TIGR00956 161 FAARCKTPQNRPDGVSREEYAKHIADVYMATYGLSHTRNTKVGNDFVRGVSGGERKRVSIAEASLGGAKIQCWDNATRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 321 DAATALEFIRALKTSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLYGGHQIFFGKANKAKEYFTNMGWYCPERQTTADFLT 400
Cdd:TIGR00956 241 DSATALEFIRALKTSANILDTTPLVAIYQCSQDAYELFDKVIVLYEGYQIYFGPADKAKQYFEKMGFKCPDRQTTADFLT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 401 SLTNPEERVAAPGYEGKLPRTAQEFESYWKKSSEYLSLIADIDEYFVECEKLNTKQAYHDSHVARQSNHISPRSPYTVSF 480
Cdd:TIGR00956 321 SLTSPAERQIKPGYEKKVPRTPQEFETYWRNSPEYAQLMKEIDEYLDRCSESDTKEAYRESHVAKQSKRTRPSSPYTVSF 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 481 PMQVKYIMGRNFLRTKNDPSIAIFTVVGQGMMGLILSSIFYNLDQTTNYMNYRGIALFFGVLYNAFASLMEILSLFEARN 560
Cdd:TIGR00956 401 SMQVKYCLARNFLRMKGNPSFTLFMVFGNIIMALILSSVFYNLPKNTSDFYSRGGALFFAILFNAFSSLLEIASMYEARP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 561 IIEKHRKYALYRPSADAIASVIFELPIKFMMSITFNLIFYFMINLRREPGRFFYYWLMAIWCTLIMSHLFRCIGSLVTTV 640
Cdd:TIGR00956 481 IVEKHRKYALYHPSADAIASIISEIPFKIIESVVFNIILYFMVNFRRTAGRFFFYLLILFICTLAMSHLFRSIGAVTKTL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 641 AQAMTPATVMLLAMVMYTGFVITTKEMLGWARWINYINPVAYVFESFMVNEFHGRYFECSNFVPSGPSYDNITFINRVCT 720
Cdd:TIGR00956 561 SEAMTPAAILLLALSIYTGFAIPRPSMLGWSKWIYYVNPLAYAFESLMVNEFHGRRFECSQYVPSGGGYDNLGVTNKVCT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 721 AIGAQPGESLVSGTTYLKMAYNYDNTHKWRNLGICIGYALFFLVVYIMLTEFNKGAMKKGEITLFLRSSLKQLKKRKELA 800
Cdd:TIGR00956 641 VVGAEPGQDYVDGDDYLKLSFQYYNSHKWRNFGIIIGFTVFFFFVYILLTEFNKGAKQKGEILVFRRGSLKRAKKAGETS 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 801 AQKQ-DIE----SASNEKVPLAEDLANSDFEKKEIvelsengltgENETFLWRDLTYEIRIKKEDRIILDHVDGWVKPGE 875
Cdd:TIGR00956 721 ASNKnDIEagevLGSTDLTDESDDVNDEKDMEKES----------GEDIFHWRNLTYEVKIKKEKRVILNNVDGWVKPGT 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 876 ITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVREALKFSAYLRQSNTTP 955
Cdd:TIGR00956 791 LTALMGASGAGKTTLLNVLAERVTTGVITGGDRLVNGRPLDSSFQRSIGYVQQQDLHLPTSTVRESLRFSAYLRQPKSVS 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 956 DKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLAD 1035
Cdd:TIGR00956 871 KSEKMEYVEEVIKLLEMESYADAVVGVPGEGLNVEQRKRLTIGVELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLAD 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1036 HGQAILCTIHQPSALLLTEFDRLLFLQEGGQTVYFGDLGENCQTLINYFEKYGADACPKDANPAEWMLKVVGAAPGSHAE 1115
Cdd:TIGR00956 951 HGQAILCTIHQPSAILFEEFDRLLLLQKGGQTVYFGDLGENSHTIINYFEKHGAPKCPEDANPAEWMLEVIGAAPGAHAN 1030
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1116 ADYFQVWRKSEEYNEIQSELDKMEVELALLPKNNDPEAHLKYAAPWWKQYVIVTARTLLQNWRTPSYIYSKLFLCLGTSL 1195
Cdd:TIGR00956 1031 QDYHEVWRNSSEYQAVKNELDRLEAELSKAEDDNDPDALSKYAASLWYQFKLVLWRTFQQYWRTPDYLYSKFFLTIFAAL 1110
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1196 FNGFSFFGGHLSLRGLQNQMFAIFLFYVPFNTMHEQMLPYFLRQRAVYEIRERPSRTFSWFAFISAQLTSEIPYQIVVGT 1275
Cdd:TIGR00956 1111 FIGFTFFKVGTSLQGLQNQMFAVFMATVLFNPLIQQYLPPFVAQRDLYEVRERPSRTFSWLAFIAAQITVEIPYNLVAGT 1190
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1276 LSFFCWYYPSGLYKNASPTNEEESRGALMWLLVVSFYCYISTMGHFCISFVEREENGANMGHFLFQMCLMFCGVLAGPAQ 1355
Cdd:TIGR00956 1191 IFFFIWYYPVGFYWNASKTGQVHERGVLFWLLSTMFFLYFSTLGQMVISFNPNADNAAVLASLLFTMCLSFCGVLAPPSR 1270
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1356 LPGFWIFMYRCNPITYLTQAMMAVGLANNHVVCAPQEYVSINPPDGISCEQFMEDYISKAGGYILADEATGQCQFCQMNN 1435
Cdd:TIGR00956 1271 MPGFWIFMYRCSPFTYLVQALLSTGLADVPVTCKVKELLTFNPPSGQTCGEYMKPYLENAGGYLLNPNATDSCSFCQYSY 1350
|
1370 1380 1390 1400
....*....|....*....|....*....|....*....|....
gi 344304674 1436 TNEFLASVGSFYSQRWRNYGIFVAFIAANVLFSIFLYWLGRVPK 1479
Cdd:TIGR00956 1351 TNDFLEPISSKYSGRWRNFGIFIAFIFFNIIATVFFYWLARVPK 1394
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
156-1371 |
1.61e-122 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 418.48 E-value: 1.61e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntygFQVDKDSKVS----YDGLTPDEIEKhyRGDVIYSAETDEHFP 231
Cdd:PLN03140 180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALA-----GKLDPSLKVSgeitYNGYRLNEFVP--RKTSAYISQNDVHVG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 232 QLTVGDTLEFAAR--------------LRTPQNRGL----GVD---RETYAKHMASVYMATY-----GILRQRNTPVGNE 285
Cdd:PLN03140 253 VMTVKETLDFSARcqgvgtrydllselARREKDAGIfpeaEVDlfmKATAMEGVKSSLITDYtlkilGLDICKDTIVGDE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 286 FVPGCSGGERKRVSIAEVSLSGANIQCWDNATRGLDAATALEFIRALKTSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLY 365
Cdd:PLN03140 333 MIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSLLQPAPETFDLFDDIILLS 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 366 GGHQIFFGKANKAKEYFTNMGWYCPERQTTADFLTSLTNPEERvaapgyegklprtaqefESYWKKSSEYLSLIAdIDEY 445
Cdd:PLN03140 413 EGQIVYQGPRDHILEFFESCGFKCPERKGTADFLQEVTSKKDQ-----------------EQYWADRNKPYRYIS-VSEF 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 446 fveceklntKQAYHDSHV-ARQSNHIS-PR------------SPYTVSFPMQVKYIMGRNFLRTKNDPSIAIFTVVGQGM 511
Cdd:PLN03140 475 ---------AERFKSFHVgMQLENELSvPFdksqshkaalvfSKYSVPKMELLKACWDKEWLLMKRNAFVYVFKTVQIII 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 512 MGLILSSIFYNLD-QTTNYMN---YRGiALFFGVLYNAFASLMEILSLFEARNIIEKHRKYALYRPSADAIASVIFELPI 587
Cdd:PLN03140 546 VAAIASTVFLRTEmHTRNEEDgalYIG-ALLFSMIINMFNGFAELALMIQRLPVFYKQRDLLFHPPWTFTLPTFLLGIPI 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 588 KFMMSITFNLIFYFMINLRREPGRFFYYWLMAIWCTLIMSHLFRCIGSLVTTVAQAMTPATVMLLAMVMYTGFVITTKEM 667
Cdd:PLN03140 625 SIIESVVWVVITYYSIGFAPEASRFFKQLLLVFLIQQMAAGIFRLIASVCRTMIIANTGGALVLLLVFLLGGFILPKGEI 704
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 668 LGWARWINYINPVAYVFESFMVNE-FHGRYFecsnfvpSGPSYDNITFInrvctaigaqpgeslvsGTTYLKMAYNYDNT 746
Cdd:PLN03140 705 PNWWEWAYWVSPLSYGFNALAVNEmFAPRWM-------NKMASDNSTRL-----------------GTAVLNIFDVFTDK 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 747 H-KWRNLGICIGYALFFLVVYIM--------------LTEFNKGAMKKGEITLFLRSSLKQLKKRKELAAQKQDIESASN 811
Cdd:PLN03140 761 NwYWIGVGALLGFTILFNVLFTLaltylnplgkkqaiISEETAEEMEGEEDSIPRSLSSADGNNTREVAIQRMSNPEGLS 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 812 EKVPLAEDLANSDFEKKEIV-ELSENGLTGENETFlWRDLTYEIRIK--KEDRI-ILDHVDGWVKPGEITALMGATGAGK 887
Cdd:PLN03140 841 KNRDSSLEAANGVAPKRGMVlPFTPLAMSFDDVNY-FVDMPAEMKEQgvTEDRLqLLREVTGAFRPGVLTALMGVSGAGK 919
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 888 TTLLNCLSDRHTVGVITDGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVREALKFSAYLRQSNTTPDKEKDAYVDYII 967
Cdd:PLN03140 920 TTLMDVLAGRKTGGYIEGDIRISGFPKKQETFARISGYCEQNDIHSPQVTVRESLIYSAFLRLPKEVSKEEKMMFVDEVM 999
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 968 DLLEMSEYADAMVGVAG-SGLNIEQRKRLTIGVELVAKPKlLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQ 1046
Cdd:PLN03140 1000 ELVELDNLKDAIVGLPGvTGLSTEQRKRLTIAVELVANPS-IIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQ 1078
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1047 PSALLLTEFDRLLFLQEGGQTVYFGDLGENCQTLINYFEKY-GADACPKDANPAEWMLKVVGAAPGSHAEADYFQVWRKS 1125
Cdd:PLN03140 1079 PSIDIFEAFDELLLMKRGGQVIYSGPLGRNSHKIIEYFEAIpGVPKIKEKYNPATWMLEVSSLAAEVKLGIDFAEHYKSS 1158
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1126 EEYneiqsELDKMEV-ELALLPKN-NDPEAHLKYAAPWWKQYVIVTARTLLQNWRTPSYIYSKLFLCLGTSLFNGFSFF- 1202
Cdd:PLN03140 1159 SLY-----QRNKALVkELSTPPPGaSDLYFATQYSQSTWGQFKSCLWKQWWTYWRSPDYNLVRFFFTLAAALMVGTIFWk 1233
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1203 -GGHLS----LRGLQNQMFAIFLFYVPFNTMHEQmlPYFLRQRAVYeIRERPSRTFSWFAFISAQLTSEIPYQIVVGTls 1277
Cdd:PLN03140 1234 vGTKRSnandLTMVIGAMYAAVLFVGINNCSTVQ--PMVAVERTVF-YRERAAGMYSALPYAIAQVVCEIPYVLIQTT-- 1308
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1278 ffcwYYPSGLYKNASptnEEESRGALMWLLVVSFYC--YISTMGHFCISFVEREENGANMGHFLFQMCLMFCGVLAGPAQ 1355
Cdd:PLN03140 1309 ----YYTLIVYAMVA---FEWTAAKFFWFYFISFFSflYFTYYGMMTVSLTPNQQVAAIFAAAFYGLFNLFSGFFIPRPK 1381
|
1290
....*....|....*.
gi 344304674 1356 LPGFWIFMYRCNPITY 1371
Cdd:PLN03140 1382 IPKWWVWYYWICPVAW 1397
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
845-1071 |
1.16e-96 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 308.79 E-value: 1.16e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 845 FLWRDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITdGVKMVNGHSLDSSFQRSIG 924
Cdd:cd03232 4 LTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGVIT-GEILINGRPLDKNFQRSTG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQDLHLQTSTVREALKFSAYLRqsnttpdkekdayvdyiidllemseyadamvgvagsGLNIEQRKRLTIGVELVAK 1004
Cdd:cd03232 83 YVEQQDVHSPNLTVREALRFSALLR------------------------------------GLSVEQRKRLTIGVELAAK 126
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 1005 PkLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEGGQTVYFG 1071
Cdd:cd03232 127 P-SILFLDEPTSGLDSQAAYNIVRFLKKLADSGQAILCTIHQPSASIFEKFDRLLLLKRGGKTVYFG 192
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
857-1291 |
2.38e-81 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 281.17 E-value: 2.38e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 857 KKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLDSSFQRSI-GYVQQQDLHLQT 935
Cdd:TIGR00955 34 ERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPIDAKEMRAIsAYVQQDDLFIPT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGS--GLNIEQRKRLTIGVELVAKPKLLlFLDE 1013
Cdd:TIGR00955 114 LTVREHLMFQAHLRMPRRVTKKEKRERVDEVLQALGLRKCANTRIGVPGRvkGLSGGERKRLAFASELLTDPPLL-FCDE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEgGQTVYFGDLGENCQtlinYFEKYGAdACP 1093
Cdd:TIGR00955 193 PTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAE-GRVAYLGSPDQAVP----FFSDLGH-PCP 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1094 KDANPAEWMLKVVGAAPGSHAEA--------DYFQVwrkSEEYNEIQSELDKMEVELALLPKNNDPEAHLKYAAPWWKQY 1165
Cdd:TIGR00955 267 ENYNPADFYVQVLAVIPGSENESreriekicDSFAV---SDIGRDMLVNTNLWSGKAGGLVKDSENMEGIGYNASWWTQF 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1166 VIVTARTLLQNWRTPSYIYSKLFLCLGTSLFNGFSFFGGHLSLRGLQNQMFAIFLFyVPFNTMHEQM--LPYFLRQRAVY 1243
Cdd:TIGR00955 344 YALLKRSWLSVLRDPLLLKVRLIQTMMTAILIGLIYLGQGLTQKGVQNINGALFLF-LTNMTFQNVFpvINVFTAELPVF 422
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 344304674 1244 eIRERPSRTFSWFAFISAQLTSEIPYQIVVGTLSFFCWYYPSGLYKNA 1291
Cdd:TIGR00955 423 -LRETRSGLYRVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGA 469
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
144-373 |
6.86e-75 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 247.18 E-value: 6.86e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 144 YFRKDDKSRYFDILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVNTYGFqVDKDSKVSYDGLTPDEIEKHYRGDVIYS 223
Cdd:cd03233 10 SFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGN-VSVEGDIHYNGIPYKEFAEKYPGEIIYV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 224 AETDEHFPQLTVGDTLEFAARLRtpqnrglgvdretyakhmasvymatygilrqrntpvGNEFVPGCSGGERKRVSIAEV 303
Cdd:cd03233 89 SEEDVHFPTLTVRETLDFALRCK------------------------------------GNEFVRGISGGERKRVSIAEA 132
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 304 SLSGANIQCWDNATRGLDAATALEFIRALKTSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLYGGHQIFFG 373
Cdd:cd03233 133 LVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIYDLFDKVLVLYEGRQIYYG 202
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
844-1071 |
9.12e-63 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 212.41 E-value: 9.12e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 844 TFLWRDLTYEIRIK--KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvGVITDGVKMVNGHSLD-SSFQ 920
Cdd:cd03213 3 TLSFRNLTVTVKSSpsKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRT-GLGVSGEVLINGRPLDkRSFR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 RSIGYVQQQDLHLQTSTVREALKFSAYLRqsnttpdkekdayvdyiidllemseyadamvgvagsGLNIEQRKRLTIGVE 1000
Cdd:cd03213 82 KIIGYVPQDDILHPTLTVRETLMFAAKLR------------------------------------GLSGGERKRVSIALE 125
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 1001 LVAKPkLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEgGQTVYFG 1071
Cdd:cd03213 126 LVSNP-SLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPSSEIFELFDKLLLLSQ-GRVIYFG 194
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
156-769 |
5.49e-50 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 188.72 E-value: 5.49e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAV-NTYGFQVDKDSKVSYDGLTPDEIekhyRGDVIYSAETDEHFPQLT 234
Cdd:TIGR00955 40 LLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFrSPKGVKGSGSVLLNGMPIDAKEM----RAISAYVQQDDLFIPTLT 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 235 VGDTLEFAARLRTPqnrglgvDRETYAKHMASV--YMATYGILRQRNTPVGNE-FVPGCSGGERKRVSIAEVSLSGANIQ 311
Cdd:TIGR00955 116 VREHLMFQAHLRMP-------RRVTKKEKRERVdeVLQALGLRKCANTRIGVPgRVKGLSGGERKRLAFASELLTDPPLL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 312 CWDNATRGLDAATALEFIRALKtSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLYGGHQIFFGKANKAKEYFTNMGWYCPE 391
Cdd:TIGR00955 189 FCDEPTSGLDSFMAYSVVQVLK-GLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPE 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 392 RQTTADFLTSLTNpeervAAPGYEGKLPRTAQEfesywKKSSEYLSLIAdiDEYFVECEKLNTKQAYHDSHVArqsnhIS 471
Cdd:TIGR00955 268 NYNPADFYVQVLA-----VIPGSENESRERIEK-----ICDSFAVSDIG--RDMLVNTNLWSGKAGGLVKDSE-----NM 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 472 PRSPYTVSFPMQVKYIMGRNFLRTKNDPSIAIFTVVGQGMMGLILSSIFYN--LDQTTnYMNYRGiALFFGVLYNAFASL 549
Cdd:TIGR00955 331 EGIGYNASWWTQFYALLKRSWLSVLRDPLLLKVRLIQTMMTAILIGLIYLGqgLTQKG-VQNING-ALFLFLTNMTFQNV 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 550 MEILSLFEA-RNIIEKHRKYALYRPSADAIASVIFELPIKFMMSITFNLIFYFMINLRREpgrFFYYWLMAIWCTLIM-- 626
Cdd:TIGR00955 409 FPVINVFTAeLPVFLRETRSGLYRVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSG---ATHFLTFLFLVTLVAnv 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 627 SHLFRC-IGSLVTTVAQAMTPATVMLLAMVMYTGFVITTKEMLGWARWINYINPVAYVFESFMVNEFHG-RYFECSNFVP 704
Cdd:TIGR00955 486 ATSFGYlISCAFSSTSMALTVGPPFVIPFLLFGGFFINSDSIPVYFKWLSYLSWFRYGNEGLLINQWSDvDNIECTSANT 565
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 705 SGPsydnitfinrvCTAigaqpgeslvSGTTYLKmAYNYDNTHKWRNLGICIGYALFF-LVVYIML 769
Cdd:TIGR00955 566 TGP-----------CPS----------SGEVILE-TLSFRNADLYLDLIGLVILIFFFrLLAYFAL 609
|
|
| ABC2_membrane |
pfam01061 |
ABC-2 type transporter; |
487-690 |
1.93e-49 |
|
ABC-2 type transporter;
Pssm-ID: 426023 [Multi-domain] Cd Length: 204 Bit Score: 174.38 E-value: 1.93e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 487 IMGRNFLRTKNDPSIAIFTVVGQGMMGLILSSIFYNLDQTTNYMNYRGIaLFFGVLYNAFASLMEILSLFEA-RNIIEKH 565
Cdd:pfam01061 1 LLKREFLRRWRDPSLGLWRLIQPILMALIFGTLFGNLGNQQGGLNRPGL-LFFSILFNAFSALSGISPVFEKeRGVLYRE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 566 RKYALYRPSADAIASVIFELPIKFMMSITFNLIFYFMINLRREPGRFFYYWLMAIWCTLIMSHLFRCIGSLVTTVAQAMT 645
Cdd:pfam01061 80 LASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAGRFFLFLLVLLLTALAASSLGLFISALAPSFEDASQ 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 344304674 646 PATVMLLAMVMYTGFVITTKEMLGWARWINYINPVAYVFESFMVN 690
Cdd:pfam01061 160 LGPLVLLPLLLLSGFFIPIDSMPVWWQWIYYLNPLTYAIEALRAN 204
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
847-1071 |
2.07e-48 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 172.46 E-value: 2.07e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 847 WRDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLD-SSFQRSIGY 925
Cdd:cd03234 6 WWDVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTSGQILFNGQPRKpDQFQKCVAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 926 VQQQDLHLQTSTVREALKFSAYLRQSNTTPDKEKDAYVDyiidLLEMSEYADAMVG-VAGSGLNIEQRKRLTIGVELVAK 1004
Cdd:cd03234 86 VRQDDILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVE----DVLLRDLALTRIGgNLVKGISGGERRRVSIAVQLLWD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 1005 PKLLlFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEGGqTVYFG 1071
Cdd:cd03234 162 PKVL-ILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGE-IVYSG 226
|
|
| PDR_CDR |
pfam06422 |
CDR ABC transporter; Corresponds to a region of the PDR/CDR subgroup of ABC transporters ... |
703-794 |
3.60e-40 |
|
CDR ABC transporter; Corresponds to a region of the PDR/CDR subgroup of ABC transporters comprising extracellular loop 3, transmembrane segment 6 and linker region.
Pssm-ID: 461906 [Multi-domain] Cd Length: 92 Bit Score: 143.37 E-value: 3.60e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 703 VPSGPSYDNITFINRVCTAIGAQPGESLVSGTTYLKMAYNYDNTHKWRNLGICIGYALFFLVVYIMLTEFNKGAMKKGEI 782
Cdd:pfam06422 1 VPSGPGYENVSGANQVCAVVGAVPGQTFVSGDDYLAASYGYSYSHLWRNFGILIAFWIFFLALYLIATEYNSAAKSKGEV 80
|
90
....*....|..
gi 344304674 783 TLFLRSSLKQLK 794
Cdd:pfam06422 81 LVFKRGKAPKLK 92
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
156-694 |
1.04e-39 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 158.12 E-value: 1.04e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVNTYGfqvdkdSKVSYDGLTPD-EIEKHYRGDVIYSAETDEHFPQLT 234
Cdd:PLN03211 83 ILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQG------NNFTGTILANNrKPTKQILKRTGFVTQDDILYPHLT 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 235 VGDTLEFAARLRTPqnRGLGVDRETYAkhmASVYMATYGILRQRNTPVGNEFVPGCSGGERKRVSIAEVSLSGANIQCWD 314
Cdd:PLN03211 157 VRETLVFCSLLRLP--KSLTKQEKILV---AESVISELGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILD 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 315 NATRGLDAATALEFIRALkTSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLYGGHQIFFGKANKAKEYFTNMGWYCPERQT 394
Cdd:PLN03211 232 EPTSGLDATAAYRLVLTL-GSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPMN 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 395 TADFLTSLTNPEERVAAPGyEGKLPRTAQEFesywkkSSEYLSLIADIDEYFVECEKLNTKQA----YHDSHVARQSNHI 470
Cdd:PLN03211 311 PADFLLDLANGVCQTDGVS-EREKPNVKQSL------VASYNTLLAPKVKAAIEMSHFPQANArfvgSASTKEHRSSDRI 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 471 SPRSPYTvsfpmQVKYIMGRNFLRTKNDP--SIAIFTVVgqgmMGLILSSIFYNLDQTTNYMNYRGIALFFGVLYNAFAS 548
Cdd:PLN03211 384 SISTWFN-----QFSILLQRSLKERKHESfnTLRVFQVI----AAALLAGLMWWHSDFRDVQDRLGLLFFISIFWGVFPS 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 549 LMEILSLFEARNIIEKHRKYALYRPSADAIASVIFELPIKFMMSITFNLIFYFMINLRREPGRFFYYWLMAIWCTLIMSH 628
Cdd:PLN03211 455 FNSVFVFPQERAIFVKERASGMYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGLKPELGAFLLTLLVLLGYVLVSQG 534
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 629 LFRCIGSLVTTVAQAMTPATVMLLAMVMYTGFVIttKEMLGWARWINYINPVAYVFEsFMVNEFHG 694
Cdd:PLN03211 535 LGLALGAAIMDAKKASTIVTVTMLAFVLTGGFYV--HKLPSCMAWIKYISTTFYSYR-LLINVQYG 597
|
|
| ABC2_membrane |
pfam01061 |
ABC-2 type transporter; |
1168-1379 |
3.73e-38 |
|
ABC-2 type transporter;
Pssm-ID: 426023 [Multi-domain] Cd Length: 204 Bit Score: 142.03 E-value: 3.73e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1168 VTARTLLQNWRTPSYIYSKLFLCLGTSLFNGFSFFGGHLSLRGLQNQMFAIF-LFYVPFNTMhEQMLPYFLRQRAVYEiR 1246
Cdd:pfam01061 1 LLKREFLRRWRDPSLGLWRLIQPILMALIFGTLFGNLGNQQGGLNRPGLLFFsILFNAFSAL-SGISPVFEKERGVLY-R 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1247 ERPSRTFSWFAFISAQLTSEIPYQIVVGTLSFFCWYYPSGLYKNASptneeesRGALMWLLVVSFYCYISTMGHFCISFV 1326
Cdd:pfam01061 79 ELASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAG-------RFFLFLLVLLLTALAASSLGLFISALA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1327 EREENGANMGHFLFQMCLMFCGVLAGPAQLPGFWIFMYRCNPITYLTQAMMAV 1379
Cdd:pfam01061 152 PSFEDASQLGPLVLLPLLLLSGFFIPIDSMPVWWQWIYYLNPLTYAIEALRAN 204
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
844-1071 |
6.63e-38 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 141.25 E-value: 6.63e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 844 TFLWRDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLD---SSFQ 920
Cdd:cd03233 3 TLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVEGDIHYNGIPYKefaEKYP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 RSIGYVQQQDLHLQTSTVREALKFSAYLRqsnttpdkekdayvdyiidllemseyADAMV-GVAGSglnieQRKRLTIGV 999
Cdd:cd03233 83 GEIIYVSEEDVHFPTLTVRETLDFALRCK--------------------------GNEFVrGISGG-----ERKRVSIAE 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1000 ELVAKPKLLLFlDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPSALLLTEFDRLLFLQEGGQtVYFG 1071
Cdd:cd03233 132 ALVSRASVLCW-DNSTRGLDSSTALEILKCIRTMADvLKTTTFVSLYQASDEIYDLFDKVLVLYEGRQ-IYYG 202
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
859-1287 |
1.27e-36 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 148.87 E-value: 1.27e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITdGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTV 938
Cdd:PLN03211 79 QERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNFT-GTILANNRKPTKQILKRTGFVTQDDILYPHLTV 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 939 REALKFSAYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAG-SGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:PLN03211 158 RETLVFCSLLRLPKSLTKQEKILVAESVISELGLTKCENTIIGNSFiRGISGGERKRVSIAHEMLINPSLLI-LDEPTSG 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1018 LDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEgGQTVYFGDLGEncqtLINYFEKYG-ADACPkdA 1096
Cdd:PLN03211 237 LDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSE-GRCLFFGKGSD----AMAYFESVGfSPSFP--M 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1097 NPAEWMLKVVGAAPGSH--AEADYFQVwRKS--EEYNEIQSELDKMEVELALLPKNNDPEAHLKYA-----------APW 1161
Cdd:PLN03211 310 NPADFLLDLANGVCQTDgvSEREKPNV-KQSlvASYNTLLAPKVKAAIEMSHFPQANARFVGSASTkehrssdrisiSTW 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1162 WKQYVIVTARtLLQNWRTPSYIYSKLFLCLGTSLFNGFSFFggHLSLRGLQNQ---MFAIFLFYVPFNTMHEQMLpyFLR 1238
Cdd:PLN03211 389 FNQFSILLQR-SLKERKHESFNTLRVFQVIAAALLAGLMWW--HSDFRDVQDRlglLFFISIFWGVFPSFNSVFV--FPQ 463
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 344304674 1239 QRAVYeIRERPSRTFSWFAFISAQLTSEIPYQIVVGTLSFFCWYYPSGL 1287
Cdd:PLN03211 464 ERAIF-VKERASGMYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGL 511
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
860-1075 |
5.15e-35 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 134.04 E-value: 5.15e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSSFQ---RSIGYVQQQDLHLQ 934
Cdd:COG1131 12 DKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLL-----GLLrpTSGEVRVLGEDVARDPAevrRRIGYVPQEPALYP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLlFLDEP 1014
Cdd:COG1131 87 DLTVRENLRFFARLYG---LPRKEARERIDELLELFGLTDAADRKVG----TLSGGMKQRLGLALALLHDPELL-ILDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 1015 TSGLDSQTAWSICKLMRKLADHGQAILCTIHqpsalLLTE----FDRLLFLQEgGQTVYFGDLGE 1075
Cdd:COG1131 159 TSGLDPEARRELWELLRELAAEGKTVLLSTH-----YLEEaerlCDRVAIIDK-GRIVADGTPDE 217
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
860-1078 |
1.00e-31 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 124.97 E-value: 1.00e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVIT-DGvkmVNGHSLDSSFQRSIGYVQQQD-LHlQT 935
Cdd:COG4555 13 KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGllKPDSGSILiDG---EDVRKEPREARRQIGVLPDERgLY-DR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAYLRQSnttPDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLLfLDEPT 1015
Cdd:COG4555 89 LTVRENIRYFAELYGL---FDEELKKRIEELIELLGLEEFLDRRVG----ELSTGMKKKVALARALVHDPKVLL-LDEPT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 1016 SGLDSQTAWSICKLMRKLADHGQAILCTIHQPS---ALLltefDRLLFLQEgGQTVYFGDLGENCQ 1078
Cdd:COG4555 161 NGLDVMARRLLREILRALKKEGKTVLFSSHIMQeveALC----DRVVILHK-GKVVAQGSLDELRE 221
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
146-373 |
9.14e-31 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 120.35 E-value: 9.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 146 RKDDKSRYFDILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLA-----VNTYGfqvdkdsKVSYDGlTPDEIEKhYRGDV 220
Cdd:cd03213 14 KSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrrtgLGVSG-------EVLING-RPLDKRS-FRKII 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 221 IYSAETDEHFPQLTVGDTLEFAARLRtpqnrglgvdretyakhmasvymatygilrqrntpvgnefvpGCSGGERKRVSI 300
Cdd:cd03213 85 GYVPQDDILHPTLTVRETLMFAAKLR------------------------------------------GLSGGERKRVSI 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 301 AEVSLSGANIQCWDNATRGLDAATALEFIRALKtSSAVLDVTPVIAIYQCSQDAYDLFDNVSVLYGGHQIFFG 373
Cdd:cd03213 123 ALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR-RLADTGRTIICSIHQPSSEIFELFDKLLLLSQGRVIYFG 194
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
848-1064 |
7.48e-30 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 118.34 E-value: 7.48e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYeiRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGVI--TDGVKMVNGHSLDSS----FQR 921
Cdd:cd03225 3 KNLSF--SYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLL-----NGLLgpTSGEVLVDGKDLTKLslkeLRR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYV-QQQDLHLQTSTVREALKFSayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADAmvgvagsglNIE-----QRKRL 995
Cdd:cd03225 76 KVGLVfQNPDDQFFGPTVEEEVAFG--LENLG-LPEEEIEERVEEALELVGLEGLRDR---------SPFtlsggQKQRV 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:cd03225 144 AIAGVLAMDPDILL-LDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLD-LLLELADRVIVLEDG 210
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
857-1045 |
3.04e-29 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 116.84 E-value: 3.04e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 857 KKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvgvITDGVKMVNGHSLDSSF---QRSIGYVQQQDLHL 933
Cdd:cd03263 11 KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELR---PTSGTAYINGYSIRTDRkaaRQSLGYCPQFDALF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKlLLFLDE 1013
Cdd:cd03263 88 DELTVREHLRFYARLK---GLPKSEIKEEVELLLRVLGLTDKANKRAR----TLSGGMKRKLSLAIALIGGPS-VLLLDE 159
|
170 180 190
....*....|....*....|....*....|..
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLAdHGQAILCTIH 1045
Cdd:cd03263 160 PTSGLDPASRRAIWDLILEVR-KGRSIILTTH 190
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
848-1064 |
5.17e-29 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 116.68 E-value: 5.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVG-VITDGVKMvngHSLDSSfQRS-- 922
Cdd:COG1136 8 RNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGglDRPTSGeVLIDGQDI---SSLSER-ELArl 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 ----IGYVQQQdLHL-QTSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVGvagsglniE----QRK 993
Cdd:COG1136 84 rrrhIGFVFQF-FNLlPELTALENVALPLLLAG---VSRKERRERARELLERVGLGDRLDHRPS--------QlsggQQQ 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 994 RLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPSalLLTEFDRLLFLQEG 1064
Cdd:COG1136 152 RVAIARALVNRPKLIL-ADEPTGNLDSKTGEEVLELLRELNrELGTTIVMVTHDPE--LAARADRVIRLRDG 220
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
848-1075 |
1.59e-28 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 115.57 E-value: 1.59e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGVI--TDG-VKmVNGHSLDSSFQRsIG 924
Cdd:COG1121 10 ENLTVSYG----GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAI-----LGLLppTSGtVR-LFGKPPRRARRR-IG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQ---DLHLQTsTVREALKFSAY----LRQSNTTPDKEKdayVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTI 997
Cdd:COG1121 79 YVPQRaevDWDFPI-TVRDVVLMGRYgrrgLFRRPSRADREA---VDEALERVGLEDLADRPIGELSGG----QQQRVLL 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAlLLTEFDRLLFLqeGGQTVYFGDLGE 1075
Cdd:COG1121 151 ARALAQDPDLLL-LDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGA-VREYFDRVLLL--NRGLVAHGPPEE 224
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
848-1064 |
2.89e-28 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 114.12 E-value: 2.89e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLD-------SS 918
Cdd:cd03255 4 KNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGglDRPTSGEVR-----VDGTDISklsekelAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 919 FQR-SIGYVQQQDLHLQTSTVREALKFSAYLRQSnttPDKEKDAYVDYIIDLLEMSEYADAMVgvagSGLNIEQRKRLTI 997
Cdd:cd03255 79 FRRrHIGFVFQSFNLLPDLTALENVELPLLLAGV---PKKERRERAEELLERVGLGDRLNHYP----SELSGGQQQRVAI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPSalLLTEFDRLLFLQEG 1064
Cdd:cd03255 152 ARALANDPKIIL-ADEPTGNLDSETGKEVMELLRELNkEAGTTIVVVTHDPE--LAEYADRIIELRDG 216
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
848-1064 |
1.95e-26 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 109.34 E-value: 1.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLD----SSFQR 921
Cdd:COG1122 4 ENLSFSYP---GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNglLKPTSGEVL-----VDGKDITkknlRELRR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYV-QQQDLHLQTSTVREALKFSayLRQSNTTPDkEKDAYVDYIIDLLEMSEYADAMV-----GvagsglnieQRKRL 995
Cdd:COG1122 76 KVGLVfQNPDDQLFAPTVEEDVAFG--PENLGLPRE-EIRERVEEALELVGLEHLADRPPhelsgG---------QKQRV 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 996 TI-GVeLVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:COG1122 144 AIaGV-LAMEPEVLV-LDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLD-LVAELADRVIVLDDG 210
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
849-1071 |
3.03e-26 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 108.00 E-value: 3.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 849 DLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGVI--TDGVKMVNGHSLDSSfQRSIGYV 926
Cdd:cd03235 4 DLTVSYG----GHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAI-----LGLLkpTSGSIRVFGKPLEKE-RKRIGYV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 927 QQQDLHLQTS--TVREALKFSAYLR----QSNTTPDKEKdayVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVE 1000
Cdd:cd03235 74 PQRRSIDRDFpiSVRDVVLMGLYGHkglfRRLSKADKAK---VDEALERVGLSELADRQIGELSGG----QQQRVLLARA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 1001 LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLqeGGQTVYFG 1071
Cdd:cd03235 147 LVQDPDLLL-LDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLG-LVLEYFDRVLLL--NRTVVASG 213
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
860-1063 |
3.61e-25 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 104.87 E-value: 3.61e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLDS---SFQRSIGYVQQQDLHLQ 934
Cdd:COG4133 14 ERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAglLPPSAGEVL-----WNGEPIRDareDYRRRLAYLGHADGLKP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSAYLRQSNTTPDKEKDAyvdyiIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:COG4133 89 ELTVRENLRFWAALYGLRADREAIDEA-----LEAVGLAGLADLPVRQLSAG----QKRRVALARLLLSPAPLWL-LDEP 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 344304674 1015 TSGLDSQT-AWsICKLMRKLADHGQAILCTIHQPSALlltEFDRLLFLQE 1063
Cdd:COG4133 159 FTALDAAGvAL-LAELIAAHLARGGAVLLTTHQPLEL---AAARVLDLGD 204
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
864-1016 |
3.78e-25 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 102.73 E-value: 3.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVITdgvkmVNGHSLDS----SFQRSIGYVQQQDLHLQTST 937
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLspTEGTIL-----LDGQDLTDderkSLRKEIGYVFQDPQLFPRLT 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 938 VREALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:pfam00005 76 VRENLRLGLLLK---GLSKREKDARAEEALEKLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLL-LDEPTA 150
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
860-1064 |
1.68e-24 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 101.71 E-value: 1.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDS---SFQRSIGYVQQQDLHLQ 934
Cdd:cd03230 12 KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIIL-----GLLkpDSGEIKVLGKDIKKepeEVKRRIGYLPEEPSLYE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSaylrqsnttpdkekdayvdyiidllemseyadamvgvagSGlnieQRKRLTIGVELVAKPKlLLFLDEP 1014
Cdd:cd03230 87 NLTVRENLKLS---------------------------------------GG----MKQRLALAQALLHDPE-LLILDEP 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1015 TSGLDSQTAWSICKLMRKLADHGQAILCTIHqpsalLLTE----FDRLLFLQEG 1064
Cdd:cd03230 123 TSGLDPESRREFWELLRELKKEGKTILLSSH-----ILEEaerlCDRVAILNNG 171
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
858-1067 |
2.23e-24 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 102.34 E-value: 2.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 858 KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSS-FQRSIGYVQQQ-DLHL 933
Cdd:cd03226 10 KKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILA-----GLIkeSSGSILLNGKPIKAKeRRKSIGYVMQDvDYQL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKFSAYLrqsntTPDKEKDAyvDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLFlDE 1013
Cdd:cd03226 85 FTDSVREELLLGLKE-----LDAGNEQA--ETVLKDLDLYALKERHPLSLSGG----QKQRLAIAAALLSGKDLLIF-DE 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLQEGGQT 1067
Cdd:cd03226 153 PTSGLDYKNMERVGELIRELAAQGKAVIVITHDYE-FLAKVCDRVLLLANGAIV 205
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
857-1371 |
3.09e-24 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 111.09 E-value: 3.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 857 KKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLDSSF-QRSIGYVQQQDLHLQT 935
Cdd:PLN03140 174 KKTKLTILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSLKVSGEITYNGYRLNEFVpRKTSAYISQNDVHVGV 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAYLRQSNTTPD-------KEKDA------------------------YVDYIIDLLEMSEYADAMVG-VA 983
Cdd:PLN03140 254 MTVKETLDFSARCQGVGTRYDllselarREKDAgifpeaevdlfmkatamegvksslITDYTLKILGLDICKDTIVGdEM 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 984 GSGLNIEQRKRLTIGvELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQA-ILCTIHQPSALLLTEFDRLLFLQ 1062
Cdd:PLN03140 334 IRGISGGQKKRVTTG-EMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEAtVLMSLLQPAPETFDLFDDIILLS 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1063 EgGQTVYFGDLgencQTLINYFEKYGAdACPKDANPAEWMLKVVgaapgshAEADYFQVW-RKSEEYNEIQ-SELD---- 1136
Cdd:PLN03140 413 E-GQIVYQGPR----DHILEFFESCGF-KCPERKGTADFLQEVT-------SKKDQEQYWaDRNKPYRYISvSEFAerfk 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1137 ------KMEVELAL-LPKNNDPEAHL---KYAAP--------WWKQYVIVTARTLLQNWRTP-----SYIYSKLFLC--L 1191
Cdd:PLN03140 480 sfhvgmQLENELSVpFDKSQSHKAALvfsKYSVPkmellkacWDKEWLLMKRNAFVYVFKTVqiiivAAIASTVFLRteM 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1192 GTSLFNGFSFFGGHLslrglqnqMFAIFLFYvpFNTMHE-----QMLPYFLRQRavyEIRERPSRTFSWFAFIsaqltSE 1266
Cdd:PLN03140 560 HTRNEEDGALYIGAL--------LFSMIINM--FNGFAElalmiQRLPVFYKQR---DLLFHPPWTFTLPTFL-----LG 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1267 IPYQIVVGTLSFFCWYYPSGLYKNASPTNEEesrgalmwLLVVSFycyISTM--GHF-CISFVEREENGANMGHFLFQMC 1343
Cdd:PLN03140 622 IPISIIESVVWVVITYYSIGFAPEASRFFKQ--------LLLVFL---IQQMaaGIFrLIASVCRTMIIANTGGALVLLL 690
|
570 580
....*....|....*....|....*....
gi 344304674 1344 LMFCGVLAGP-AQLPGFWIFMYRCNPITY 1371
Cdd:PLN03140 691 VFLLGGFILPkGEIPNWWEWAYWVSPLSY 719
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
157-317 |
6.70e-24 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 99.26 E-value: 6.70e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 157 LKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG--LTPDEIeKHYRGDVIYSAETDEHFPQLT 234
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIA----GLLSPTEGTILLDGqdLTDDER-KSLRKEIGYVFQDPQLFPRLT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 235 VGDTLEFAARLRTPQNRGLGVDretyakhmASVYMATYGILRQRNTPVGNeFVPGCSGGERKRVSIAEVSLSGANIQCWD 314
Cdd:pfam00005 76 VRENLRLGLLLKGLSKREKDAR--------AEEALEKLGLGDLADRPVGE-RPGTLSGGQRQRVAIARALLTKPKLLLLD 146
|
...
gi 344304674 315 NAT 317
Cdd:pfam00005 147 EPT 149
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
156-766 |
1.13e-23 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 109.55 E-value: 1.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVNTYGFQVDKDSKVSydGLtPDEIEKHYR--GdviYSAETDEHFPQL 233
Cdd:PLN03140 895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDIRIS--GF-PKKQETFARisG---YCEQNDIHSPQV 968
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 234 TVGDTLEFAARLRTPQNrglgVDRETYAKHMASVyMATYGILRQRNTPVGNEFVPGCSGGERKRVSIAEVSLSGANIQCW 313
Cdd:PLN03140 969 TVRESLIYSAFLRLPKE----VSKEEKMMFVDEV-MELVELDNLKDAIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFM 1043
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 314 DNATRGLDAATALEFIRALKTSsavLDV--TPVIAIYQCSQDAYDLFDNVSVL-YGGHQIFFG----KANKAKEYFTNMG 386
Cdd:PLN03140 1044 DEPTSGLDARAAAIVMRTVRNT---VDTgrTVVCTIHQPSIDIFEAFDELLLMkRGGQVIYSGplgrNSHKIIEYFEAIP 1120
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 387 WY--CPERQTTADFLTSLTNpeerVAApgyEGKLprtAQEFESYWKKSSEYLSLIADIDEyfvecekLNT-KQAYHDSHV 463
Cdd:PLN03140 1121 GVpkIKEKYNPATWMLEVSS----LAA---EVKL---GIDFAEHYKSSSLYQRNKALVKE-------LSTpPPGASDLYF 1183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 464 ARQsnhisprspYTVSFPMQVKYIMGRNFLRTKNDPSIA----IFTVVGQGMMGlilsSIFYNLDqtTNYMNYRGIALFF 539
Cdd:PLN03140 1184 ATQ---------YSQSTWGQFKSCLWKQWWTYWRSPDYNlvrfFFTLAAALMVG----TIFWKVG--TKRSNANDLTMVI 1248
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 540 GVLYNAF-------ASLMEILSLFEaRNIIEKHRKYALYRPSADAIASVIFELPIKFMMSITFNLIFYFMINLRREPGRF 612
Cdd:PLN03140 1249 GAMYAAVlfvginnCSTVQPMVAVE-RTVFYRERAAGMYSALPYAIAQVVCEIPYVLIQTTYYTLIVYAMVAFEWTAAKF 1327
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 613 FYYWLMAIWCTLIMSHLFRCIGSLVTTVAQAMTPATVMLLAMVMYTGFVITTKEMLGWARWINYINPVAYVFESFMVNEF 692
Cdd:PLN03140 1328 FWFYFISFFSFLYFTYYGMMTVSLTPNQQVAAIFAAAFYGLFNLFSGFFIPRPKIPKWWVWYYWICPVAWTVYGLIVSQY 1407
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344304674 693 HgryfecsnfvpsgpsyDNITFINrvctAIGAQPGESLvsgTTYLKMAYNYDNTHKWRNLGICIGYALFFLVVY 766
Cdd:PLN03140 1408 G----------------DVEDTIK----VPGGAPDPTI---KWYIQDHYGYDPDFMGPVAAVLVGFTVFFAFIF 1458
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
864-1041 |
1.86e-23 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 100.59 E-value: 1.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVG-VITDGvKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVRE 940
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLrpTSGsVLFDG-EDITGLPPHEIARLGIGRTFQIPRLFPELTVLE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSAYLRQSNTT-------PDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:cd03219 95 NVMVAAQARTGSGLllararrEEREARERAEELLERVGLADLADRPAG----ELSYGQQRRLEIARALATDPKLLL-LDE 169
|
170 180
....*....|....*....|....*...
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAIL 1041
Cdd:cd03219 170 PAAGLNPEETEELAELIRELRERGITVL 197
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
859-1064 |
7.70e-23 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 104.84 E-value: 7.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLDS----SFQRSIGYVQQQDlHLQ 934
Cdd:COG4988 348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP---YSGSILINGVDLSDldpaSWRRQIAWVPQNP-YLF 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFsaylrqSNTTPDKE------KDAYVDYIIDLLEmsEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLL 1008
Cdd:COG4988 424 AGTIRENLRL------GRPDASDEeleaalEAAGLDEFVAALP--DGLDTPLGEGGRGLSGGQAQRLALARALLRDAPLL 495
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 1009 LfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTiHQPSalLLTEFDRLLFLQEG 1064
Cdd:COG4988 496 L-LDEPTAHLDAETEAEILQALRRLAKGRTVILIT-HRLA--LLAQADRILVLDDG 547
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
848-1065 |
8.92e-23 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 99.35 E-value: 8.92e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDS----SFQR 921
Cdd:COG1120 5 ENLSVGYG----GRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALA-----GLLkpSSGEVLLDGRDLASlsrrELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYVQQQDLHLQTSTVREALKFSAYLRQSNTTPDKEKD-AYVDYIIDLLEMSEYADAMV-----GvagsglnieQRKRL 995
Cdd:COG1120 76 RIAYVPQEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDrEAVEEALERTGLEHLADRPVdelsgG---------ERQRV 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPS-ALLLteFDRLLFLQEGG 1065
Cdd:COG1120 147 LIARALAQEPPLLL-LDEPTSHLDLAHQLEVLELLRRLArERGRTVVMVLHDLNlAARY--ADRLVLLKDGR 215
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
863-1064 |
1.12e-22 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 97.98 E-value: 1.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITDGVKMVNGHSLDssfQRSIGYVQQQDL---HLqtsT 937
Cdd:cd03259 15 ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAglERPDSGEILIDGRDVTGVPPE---RRNIGMVFQDYAlfpHL---T 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 938 VREALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVgvagSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:cd03259 89 VAENIAFGLKLR---GVPKAEIRARVRELLELVGLEGLLNRYP----HELSGGQQQRVALARALAREPSLLL-LDEPLSA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 344304674 1018 LDSQTAWSICKLMRKL-ADHG-QAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:cd03259 161 LDAKLREELREELKELqRELGiTTIYVTHDQEEALALA--DRIAVMNEG 207
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
864-1045 |
1.67e-22 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 97.44 E-value: 1.67e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhTVGVITDGVKMVNGHSLDS---SFQRSIGYVQQQDLHLQTSTVRE 940
Cdd:cd03265 16 VRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLT---TLLKPTSGRATVAGHDVVReprEVRRRIGIVFQDLSVDDELTGWE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLnieqRKRLTIGVELVAKPKlLLFLDEPTSGLDS 1020
Cdd:cd03265 93 NLYIHARLY---GVPGAERRERIDELLDFVGLLEAADRLVKTYSGGM----RRRLEIARSLVHRPE-VLFLDEPTIGLDP 164
|
170 180
....*....|....*....|....*.
gi 344304674 1021 QTAWSICKLMRKL-ADHGQAILCTIH 1045
Cdd:cd03265 165 QTRAHVWEYIEKLkEEFGMTILLTTH 190
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
139-373 |
2.84e-22 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 96.96 E-value: 2.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 139 VDGSRYFRKDDKSRyfDILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLA------VNTYGfqvdkdsKVSYDG--LTPD 210
Cdd:cd03234 7 WDVGLKAKNWNKYA--RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISgrveggGTTSG-------QILFNGqpRKPD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 211 EIEKHyrgdVIYSAETDEHFPQLTVGDTLEFAARLRTPqnrglgvdrETYAKHMASVYMATYGILRQRNTPVGNEFVPGC 290
Cdd:cd03234 78 QFQKC----VAYVRQDDILLPGLTVRETLTYTAILRLP---------RKSSDAIRKKRVEDVLLRDLALTRIGGNLVKGI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 291 SGGERKRVSIAEVSLSGANIQCWDNATRGLDAATALEFIRALK----TSSAVLdvtpvIAIYQCSQDAYDLFDNVSVLYG 366
Cdd:cd03234 145 SGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSqlarRNRIVI-----LTIHQPRSDLFRLFDRILLLSS 219
|
....*..
gi 344304674 367 GHQIFFG 373
Cdd:cd03234 220 GEIVYSG 226
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
864-1045 |
3.08e-22 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 99.00 E-value: 3.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhTVGVITDGVKMVNGHSLDSS---FQRSIGYVQQQ-----DLhlqt 935
Cdd:TIGR01188 9 VDGVNFKVREGEVFGFLGPNGAGKTTTIRMLT---TLLRPTSGTARVAGYDVVREprkVRRSIGIVPQYasvdeDL---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 sTVREALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLlFLDEPT 1015
Cdd:TIGR01188 82 -TGRENLEMMGRLY---GLPKDEAEERAEELLELFELGEAADRPVGTYSGG----MRRRLDIAASLIHQPDVL-FLDEPT 152
|
170 180 190
....*....|....*....|....*....|
gi 344304674 1016 SGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:TIGR01188 153 TGLDPRTRRAIWDYIRALKEEGVTILLTTH 182
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
855-1064 |
3.65e-22 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 97.17 E-value: 3.65e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 855 RIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHtvgVITDGVKMVNGHSL----DSSFQRSIGYVQQQD 930
Cdd:cd03252 9 RYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFY---VPENGRVLVDGHDLaladPAWLRRQVGVVLQEN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 LhLQTSTVREALKFSaylrqsNTTPDKEKDAYVDYIID----LLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPK 1006
Cdd:cd03252 86 V-LFNRSIRDNIALA------DPGMSMERVIEAAKLAGahdfISELPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPR 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1007 LLLFlDEPTSGLDSQTAWSICKLMRKLADhGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:cd03252 159 ILIF-DEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKNA--DRIIVMEKG 212
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
854-1075 |
3.96e-22 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 97.46 E-value: 3.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRIILDHVDgW-VKPGEITALMGATGAGKTTLLNCLSDRH------TVGVItdGVKMvNGHSLdssFQ--RSIG 924
Cdd:COG1119 9 VTVRRGGKTILDDIS-WtVKPGEHWAILGPNGAGKSTLLSLITGDLpptygnDVRLF--GERR-GGEDV---WElrKRIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQqDLHLQ---TSTVREAL---KFSAYLRQSNTTPDKEKDAyvDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIG 998
Cdd:COG1119 82 LVSP-ALQLRfprDETVLDVVlsgFFDSIGLYREPTDEQRERA--RELLELLGLAHLADRPFGTLSQG----EQRRVLIA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 999 VELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHG--QAILCTiHQPSAlLLTEFDRLLFLQEgGQTVYFGDLGE 1075
Cdd:COG1119 155 RALVKDPELLI-LDEPTAGLDLGARELLLALLDKLAAEGapTLVLVT-HHVEE-IPPGITHVLLLKD-GRVVAAGPKEE 229
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
848-1045 |
7.75e-22 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 95.51 E-value: 7.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhTVGVITDGVKMVNG---HSLDSSFQRSIG 924
Cdd:cd03266 5 DALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLA---GLLEPDAGFATVDGfdvVKEPAEARRRLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQDLHLQTSTVREALKFSAYLRQSNTTpdkEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAK 1004
Cdd:cd03266 82 FVSDSTGLYDRLTARENLEYFAGLYGLKGD---ELTARLEELADRLGMEELLDRRVG----GFSTGMRQKVAIARALVHD 154
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 344304674 1005 PKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:cd03266 155 PPVLL-LDEPTTGLDVMATRALREFIRQLRALGKCILFSTH 194
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
853-1064 |
1.30e-21 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 93.08 E-value: 1.30e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTV--GVITdgvkmVNGHSLDSSF----QRSIGYV 926
Cdd:cd00267 4 NLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPtsGEIL-----IDGKDIAKLPleelRRRIGYV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 927 QQQdlhlqtstvrealkfsaylrqsnttpdkekdayvdyiidllemseyadamvgvagSGlniEQRKRLTIGVELVAKPK 1006
Cdd:cd00267 79 PQL-------------------------------------------------------SG---GQRQRVALARALLLNPD 100
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1007 LLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:cd00267 101 LLL-LDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPE-LAELAADRVIVLKDG 156
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
848-1064 |
3.23e-21 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 92.06 E-value: 3.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYeiRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLD----SSFQR 921
Cdd:cd03228 4 KNVSF--SYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLrlYDPTSGEIL-----IDGVDLRdldlESLRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYVqQQDLHLQTSTVREalkfsaylrqsNttpdkekdayvdyiidLLemseyadamvgvagSGLnieQRKRLTIGVEL 1001
Cdd:cd03228 77 NIAYV-PQDPFLFSGTIRE-----------N----------------IL--------------SGG---QRQRIAIARAL 111
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1002 VAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTiHQPSALLLteFDRLLFLQEG 1064
Cdd:cd03228 112 LRDPPILI-LDEATSALDPETEALILEALRALAKGKTVIVIA-HRLSTIRD--ADRIIVLDDG 170
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
860-1064 |
4.23e-21 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 93.89 E-value: 4.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDS-------SFQRSIGYVQQQ- 929
Cdd:COG1127 17 DRVVLDGVSLDVPRGEILAIIGGSGSGKSVLL-----KLIIGLLrpDSGEILVDGQDITGlsekelyELRRRIGMLFQGg 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 930 ----DLhlqtsTVREALKFsaYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGvagsglniE----QRKRLTIGVEL 1001
Cdd:COG1127 92 alfdSL-----TVFENVAF--PLREHTDLSEAEIRELVLEKLELVGLPGAADKMPS--------ElsggMRKRVALARAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 1002 VAKPKlLLFLDEPTSGLDSQTAWSICKLMRKLADHGQA--ILCTiHQ-PSALLLTefDRLLFLQEG 1064
Cdd:COG1127 157 ALDPE-ILLYDEPTAGLDPITSAVIDELIRELRDELGLtsVVVT-HDlDSAFAIA--DRVAVLADG 218
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
864-1041 |
5.47e-21 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 94.34 E-value: 5.47e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDS-------------SFQRS------ 922
Cdd:COG0411 20 VDDVSLEVERGEIVGLIGPNGAGKTTLFNLIT-----GFYrpTSGRILFDGRDITGlpphriarlgiarTFQNPrlfpel 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 -------IGyvqqQDLHLQTSTVREALKFSAYLRQsnttpDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRL 995
Cdd:COG0411 95 tvlenvlVA----AHARLGRGLLAALLRLPRARRE-----EREARERAEELLERVGLADRADEPAG----NLSYGQQRRL 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAIL 1041
Cdd:COG0411 162 EIARALATEPKLLL-LDEPAAGLNPEETEELAELIRRLrDERGITIL 207
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
873-1064 |
1.14e-20 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 91.97 E-value: 1.14e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 873 PGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLDSS--------FQRSIGYV-QQQDL--HLqtsTVR 939
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAglEKPDGGTIV-----LNGTVLFDSrkkinlppQQRKIGLVfQQYALfpHL---NVR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFsAYLRQSNttpdKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:cd03297 94 ENLAF-GLKRKRN----REDRISVDELLDLLGLDHLLNRYPAQLSGG----EKQRVALARALAAQPELLL-LDEPFSALD 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 344304674 1020 SQTAWSICKLMRKLADHGQ--AILCTiHQPS-ALLLTefDRLLFLQEG 1064
Cdd:cd03297 164 RALRLQLLPELKQIKKNLNipVIFVT-HDLSeAEYLA--DRIVVMEDG 208
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
858-1065 |
1.58e-20 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 92.29 E-value: 1.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 858 KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLD----SSFQRSIGYVqQQDLHL 933
Cdd:cd03251 12 GDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDV---DSGRILIDGHDVRdytlASLRRQIGLV-SQDVFL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALkfsAYLRQSNTTPDKE---KDAYVDYIIDllEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLf 1010
Cdd:cd03251 88 FNDTVAENI---AYGRPGATREEVEeaaRAANAHEFIM--ELPEGYDTVIGERGVKLSGGQRQRIAIARALLKDPPILI- 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1011 LDEPTSGLDSQTAWSICKLMRKLADHGQAI-----LCTIHQPsallltefDRLLFLQEGG 1065
Cdd:cd03251 162 LDEATSALDTESERLVQAALERLMKNRTTFviahrLSTIENA--------DRIVVLEDGK 213
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
863-1075 |
2.45e-20 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 91.34 E-value: 2.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLD--SSFQRS---IGYVQQ-----QD 930
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIM-----GLLppRSGSIRFDGRDITglPPHERAragIGYVPEgrrifPE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 LhlqtsTVREALKFSAYLRqsnttPDKEKDAYVDYIIDLL-EMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLL 1009
Cdd:cd03224 90 L-----TVEENLLLGAYAR-----RRAKRKARLERVYELFpRLKERRKQLAGTLSGG----EQQMLAIARALMSRPKLLL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1010 fLDEPTSGLDSQTAWSICKLMRKLADHGQAILcTIHQ--PSALLLTefDRLLFLqEGGQTVYFGDLGE 1075
Cdd:cd03224 156 -LDEPSEGLAPKIVEEIFEAIRELRDEGVTIL-LVEQnaRFALEIA--DRAYVL-ERGRVVLEGTAAE 218
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
860-1064 |
3.71e-20 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 89.55 E-value: 3.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTS 936
Cdd:cd03229 12 QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAglEEPDSGSILiDGEDLTDLEDELPPLRRRIGMVFQDFALFPHL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKFsaylrqsnttpdkekdayvdyiidllemseyadamvgvagsGLNIEQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:cd03229 92 TVLENIAL-----------------------------------------GLSGGQQQRVALARALAMDPDVLL-LDEPTS 129
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 344304674 1017 GLDSQTAWSICKLMRKLAD-HGQAILCTIHQPsALLLTEFDRLLFLQEG 1064
Cdd:cd03229 130 ALDPITRREVRALLKSLQAqLGITVVLVTHDL-DEAARLADRVVVLRDG 177
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
859-1064 |
3.85e-20 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 96.37 E-value: 3.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdRH---TVGVITdgvkmVNGHSLD----SSFQRSIGYVQQqDL 931
Cdd:COG4987 346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLL-RFldpQSGSIT-----LGGVDLRdldeDDLRRRIAVVPQ-RP 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLQTSTVREALKFSAylrqsnttPDKEKDAyvdyIIDLLEMSEYA----------DAMVGVAGSGLNIEQRKRLTIGVEL 1001
Cdd:COG4987 419 HLFDTTLRENLRLAR--------PDATDEE----LWAALERVGLGdwlaalpdglDTWLGEGGRRLSGGERRRLALARAL 486
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1002 VAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAdHGQAILCTIHQPSAllLTEFDRLLFLQEG 1064
Cdd:COG4987 487 LRDAPILL-LDEPTEGLDAATEQALLADLLEAL-AGRTVLLITHRLAG--LERMDRILVLEDG 545
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
848-1064 |
4.59e-20 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 96.83 E-value: 4.59e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYeiRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVItdgvkMVNGHSLD----SSFQR 921
Cdd:COG2274 477 ENVSF--RYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLglYEPTSGRI-----LIDGIDLRqidpASLRR 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYVqQQDLHLQTSTVREALKFsaylrqSNTTPDKE------KDAYVDYIIDLLEMSeYaDAMVGVAGSGLNIEQRKRL 995
Cdd:COG2274 550 QIGVV-LQDVFLFSGTIRENITL------GDPDATDEeiieaaRLAGLHDFIEALPMG-Y-DTVVGEGGSNLSGGQRQRL 620
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAdHGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:COG2274 621 AIARALLRNPRILI-LDEATSALDAETEAIILENLRRLL-KGRTVIIIAHRLSTIRLA--DRIIVLDKG 685
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
853-1064 |
5.10e-20 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 90.75 E-value: 5.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIK------KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVIT-DGvkmVNGHSLD-SSFQRS 922
Cdd:cd03254 2 EIEFEnvnfsyDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRfyDPQKGQILiDG---IDIRDISrKSLRSM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 IGYVqQQDLHLQTSTVREALKFSaylrqSNTTPDKE-----KDAYVDYIIDLLEmsEYADAMVGVAGSGLNIEQRKRLTI 997
Cdd:cd03254 79 IGVV-LQDTFLFSGTIMENIRLG-----RPNATDEEvieaaKEAGAHDFIMKLP--NGYDTVLGENGGNLSQGERQLLAI 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAdHGQAILCTIHQPSALLltEFDRLLFLQEG 1064
Cdd:cd03254 151 ARAMLRDPKILI-LDEATSNIDTETEKLIQEALEKLM-KGRTSIIIAHRLSTIK--NADKILVLDDG 213
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
797-1061 |
7.03e-20 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 95.43 E-value: 7.03e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 797 KELAAQ---KQDIESASNEKVPLAEDLANSDFEKKEIVELSENGLTGENETFlwrdlTYEIRikkedRIILDHVDGWVKP 873
Cdd:TIGR02857 278 RQLGAQyhaRADGVAAAEALFAVLDAAPRPLAGKAPVTAAPASSLEFSGVSV-----AYPGR-----RPALRPVSFTVPP 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 874 GEITALMGATGAGKTTLLNCLSDrhtVGVITDGVKMVNGHSLD----SSFQRSIGYVQQQDlHLQTSTVREALKFS---- 945
Cdd:TIGR02857 348 GERVALVGPSGAGKSTLLNLLLG---FVDPTEGSIAVNGVPLAdadaDSWRDQIAWVPQHP-FLFAGTIAENIRLArpda 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 946 --AYLRQSnttpdkEKDAYVDYIIDLLEmsEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTA 1023
Cdd:TIGR02857 424 sdAEIREA------LERAGLDEFVAALP--QGLDTPIGEGGAGLSGGQAQRLALARAFLRDAPLLL-LDEPTAHLDAETE 494
|
250 260 270
....*....|....*....|....*....|....*...
gi 344304674 1024 WSICKLMRKLADhGQAILCTIHQPSalLLTEFDRLLFL 1061
Cdd:TIGR02857 495 AEVLEALRALAQ-GRTVLLVTHRLA--LAALADRIVVL 529
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
860-1019 |
2.42e-19 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 88.02 E-value: 2.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGeITALMGATGAGKTTLLNCLSD--RHTVGVIT-DGVKMVNGHsldSSFQRSIGYVQQQDLHLQTS 936
Cdd:cd03264 12 KKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATltPPSSGTIRiDGQDVLKQP---QKLRRRIGYLPQEFGVYPNF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVGvAGSGlniEQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:cd03264 88 TVREFLDYIAWLKG---IPSKEVKARVDEVLELVNLGDRAKKKIG-SLSG---GMRRRVGIAQALVGDPSILI-VDEPTA 159
|
...
gi 344304674 1017 GLD 1019
Cdd:cd03264 160 GLD 162
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
859-1075 |
3.42e-19 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 88.33 E-value: 3.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDS-------SFQRSIGYVQQQ 929
Cdd:cd03261 11 GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLL-----RLIVGLLrpDSGEVLIDGEDISGlseaelyRLRRRMGMLFQS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 930 DLhLQTS-TVREALKFsaYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKlL 1008
Cdd:cd03261 86 GA-LFDSlTVFENVAF--PLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGG----MKKRVALARALALDPE-L 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 1009 LFLDEPTSGLDSQTAWSICKLMRKLADHGQA--ILCTiHQPSALLLTEfDRLLFLQEgGQTVYFGDLGE 1075
Cdd:cd03261 158 LLYDEPTAGLDPIASGVIDDLIRSLKKELGLtsIMVT-HDLDTAFAIA-DRIAVLYD-GKIVAEGTPEE 223
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
848-1065 |
4.01e-19 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 86.34 E-value: 4.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSLdSSFQRsigy 925
Cdd:cd03214 3 ENLSVGYG----GRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLA-----GLLKpsSGEILLDGKDL-ASLSP---- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 926 vqqqdlhlqtstvREALKFSAYLRQsnttpdkekdayvdyIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKP 1005
Cdd:cd03214 69 -------------KELARKIAYVPQ---------------ALELLGLAHLADRPFNELSGG----ERQRVLLARALAQEP 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1006 KLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPS-ALLLteFDRLLFLQEGG 1065
Cdd:cd03214 117 PILL-LDEPTSHLDIAHQIELLELLRRLAReRGKTVVMVLHDLNlAARY--ADRVILLKDGR 175
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
848-1033 |
4.12e-19 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 88.02 E-value: 4.12e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVG-VITDG--VKMVNGHSLdSSFQRS 922
Cdd:cd03258 5 KNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINglERPTSGsVLVDGtdLTLLSGKEL-RKARRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 IGYVQQQDLHLQTSTVREALkfsAYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELV 1002
Cdd:cd03258 84 IGMIFQHFNLLSSRTVFENV---ALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGG----QKQRVGIARALA 156
|
170 180 190
....*....|....*....|....*....|.
gi 344304674 1003 AKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 1033
Cdd:cd03258 157 NNPKVLL-CDEATSALDPETTQSILALLRDI 186
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
860-1064 |
5.25e-19 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 86.89 E-value: 5.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMVNGHS----LDSSFQRSIGYvqqqdLH 932
Cdd:cd03268 12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILglIKPDSGEITfDGKSYQKNIEalrrIGALIEAPGFY-----PN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 933 LqtsTVREALKFSAYLRQsntTPDKEkdayVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLLfLD 1012
Cdd:cd03268 87 L---TARENLRLLARLLG---IRKKR----IDEVLDVVGLKDSAKKKVK----GFSLGMKQRLGIALALLGNPDLLI-LD 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1013 EPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEfDRLLFLQEG 1064
Cdd:cd03268 152 EPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVA-DRIGIINKG 202
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
863-1069 |
1.10e-18 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 86.18 E-value: 1.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVRE 940
Cdd:cd03269 15 ALDDISFSVEKGEIFGLLGPNGAGKTTTI-----RMILGIIlpDSGEVLFDGKPLDIAARNRIGYLPEERGLYPKMKVID 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDS 1020
Cdd:cd03269 90 QLVYLAQLK---GLKKEEARRRIDEWLERLELSEYANKRVEELSKG----NQQKVQFIAAVIHDPELLI-LDEPFSGLDP 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 344304674 1021 QTAWSICKLMRKLADHGQAILCTIHQPSalLLTEF-DRLLFLQEGGQTVY 1069
Cdd:cd03269 162 VNVELLKDVIRELARAGKTVILSTHQME--LVEELcDRVLLLNKGRAVLY 209
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
859-1064 |
1.15e-18 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 91.76 E-value: 1.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdR---HTVGVITdgvkmVNGHSLD----SSFQRSIGYVqQQDL 931
Cdd:COG1132 351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLL-RfydPTSGRIL-----IDGVDIRdltlESLRRQIGVV-PQDT 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLQTSTVREALKFSAylrqsNTTPDKE-----KDAYVDYIIDLLEMSeYaDAMVGVAGSGLNIEQRKRLTIGVELVAKPK 1006
Cdd:COG1132 424 FLFSGTIRENIRYGR-----PDATDEEveeaaKAAQAHEFIEALPDG-Y-DTVVGERGVNLSGGQRQRIAIARALLKDPP 496
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 1007 LLLfLDEPTSGLDSQTAWSICKLMRKLAdHGQAILcTI-HQPSAllLTEFDRLLFLQEG 1064
Cdd:COG1132 497 ILI-LDEATSALDTETEALIQEALERLM-KGRTTI-VIaHRLST--IRNADRILVLDDG 550
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
858-1064 |
1.49e-18 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 86.85 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 858 KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvgvITDGVKMVNGHSLDS-------SFQRSIGYVQQQd 930
Cdd:cd03256 11 PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVE---PTSGSVLIDGTDINKlkgkalrQLRRQIGMIFQQ- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 LHL----------------QTSTVREalkfsayLRQSNTTPDKEKdAYvdYIIDLLEMSEYADAMVGVAGSGlnieQRKR 994
Cdd:cd03256 87 FNLierlsvlenvlsgrlgRRSTWRS-------LFGLFPKEEKQR-AL--AALERVGLLDKAYQRADQLSGG----QQQR 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 995 LTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:cd03256 153 VAIARALMQQPKLIL-ADEPVASLDPASSRQVMDLLKRINrEEGITVIVSLHQVD-LAREYADRIVGLKDG 221
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
164-332 |
1.82e-18 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 85.61 E-value: 1.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLEFAA 243
Cdd:COG4133 25 LAAGEALALTGPNGSGKTTLLRILA----GLLPPSAGEVLWNGEPIRDAREDYRRRLAYLGHADGLKPELTVRENLRFWA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 244 RLrtpqnRGLGVDRETYAKHMASVymatyGILRQRNTPVGNefvpgCSGGERKRVSIAEVSLSGANIqcW--DNATRGLD 321
Cdd:COG4133 101 AL-----YGLRADREAIDEALEAV-----GLAGLADLPVRQ-----LSAGQKRRVALARLLLSPAPL--WllDEPFTALD 163
|
170
....*....|.
gi 344304674 322 AATALEFIRAL 332
Cdd:COG4133 164 AAGVALLAELI 174
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
848-1071 |
1.86e-18 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 86.02 E-value: 1.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDrhtVGVITDGVKMVNGHSL-------DSSFQ 920
Cdd:cd03257 5 KNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILG---LLKPTSGSIIFDGKDLlklsrrlRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 RSIGYVQQqdlHLQTS-----TVREALKFsAYLRQSNTTPDKEKDAYVDYIIDLLEMSE-----YADAMVGvaGsglnie 990
Cdd:cd03257 82 KEIQMVFQ---DPMSSlnprmTIGEQIAE-PLRIHGKLSKKEARKEAVLLLLVGVGLPEevlnrYPHELSG--G------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 991 QRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPSalLLTEF-DRLLFLQeGGQTV 1068
Cdd:cd03257 150 QRQRVAIARALALNPKLLI-ADEPTSALDVSVQAQILDLLKKLQEeLGLTLLFITHDLG--VVAKIaDRVAVMY-AGKIV 225
|
...
gi 344304674 1069 YFG 1071
Cdd:cd03257 226 EEG 228
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
848-1061 |
2.25e-18 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 86.68 E-value: 2.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGvKMVNGHSLDssfqrsIG 924
Cdd:COG1116 11 RGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAglEKPTSGEVLvDG-KPVTGPGPD------RG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQDLHLQTSTVRE----ALKFSaylrqsnTTPDKEKDAYVDYIIDLLEMSEYADAMV-----GvagsglnieQRKRL 995
Cdd:COG1116 84 VVFQEPALLPWLTVLDnvalGLELR-------GVPKAERRERARELLELVGLAGFEDAYPhqlsgG---------MRQRV 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPS-ALLLTefDRLLFL 1061
Cdd:COG1116 148 AIARALANDPEVLL-MDEPFGALDALTRERLQDELLRLwQETGKTVLFVTHDVDeAVFLA--DRVVVL 212
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
848-1041 |
2.91e-18 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 89.96 E-value: 2.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRI-ILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLDS------- 917
Cdd:COG1123 264 RNLSKRYPVRGKGGVrAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLglLRPTSGSIL-----FDGKDLTKlsrrslr 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 918 SFQRSIGYVQQqdlHLQTS-----TVREALKFSayLRQSNTTPDKEKDAYVDYIIDLLEMS-EYADAMV-----Gvagsg 986
Cdd:COG1123 339 ELRRRVQMVFQ---DPYSSlnprmTVGDIIAEP--LRLHGLLSRAERRERVAELLERVGLPpDLADRYPhelsgG----- 408
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 987 lnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAIL 1041
Cdd:COG1123 409 ----QRQRVAIARALALEPKLLI-LDEPTSALDVSVQAQILNLLRDLQReLGLTYL 459
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
848-1041 |
3.26e-18 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 85.22 E-value: 3.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGvKMVNGHSldssfqRSIG 924
Cdd:cd03293 4 RNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAglERPTSGEVLvDG-EPVTGPG------PDRG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQDLHLQTSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAK 1004
Cdd:cd03293 77 YVFQQDALLPWLTVLDNVALGLELQG---VPKAEARERAEELLELVGLSGFENAYPHQLSGG----MRQRVALARALAVD 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 344304674 1005 PKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAIL 1041
Cdd:cd03293 150 PDVLL-LDEPFSALDALTREQLQEELLDIwRETGKTVL 186
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
848-1064 |
6.21e-18 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 89.19 E-value: 6.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTyeIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLD--SSFQRS--I 923
Cdd:COG1123 8 RDLS--VRYPGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRISGEVLLDGRDLLelSEALRGrrI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 924 GYV-QQQDLHLQTSTVREALKFSayLRQSNTTPDKEKDAyvdyIIDLLEmseyadaMVGVAG---------SGlniEQRK 993
Cdd:COG1123 86 GMVfQDPMTQLNPVTVGDQIAEA--LENLGLSRAEARAR----VLELLE-------AVGLERrldryphqlSG---GQRQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 994 RLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPsALLLTEFDRLLFLQEG 1064
Cdd:COG1123 150 RVAIAMALALDPDLLI-ADEPTTALDVTTQAEILDLLRELqRERGTTVLLITHDL-GVVAEIADRVVVMDDG 219
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
860-1064 |
2.03e-17 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 82.58 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMVNGHSLDSSFQRSIGYV-QQQDL--HL 933
Cdd:cd03262 12 DFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINllEEPDSGTIIiDGLKLTDDKKNINELRQKVGMVfQQFNLfpHL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 qtsTVREALKFSayLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLFlDE 1013
Cdd:cd03262 92 ---TVLENITLA--PIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGG----QQQRVAIARALAMNPKVMLF-DE 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHQpsalllTEF-----DRLLFLQEG 1064
Cdd:cd03262 162 PTSALDPELVGEVLDVMKDLAEEGMTMVVVTHE------MGFarevaDRVIFMDDG 211
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
848-1064 |
2.91e-17 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 82.93 E-value: 2.91e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMvnGHSLDSSFQRSIG 924
Cdd:COG1124 5 RNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAglERPWSGEVTfDGRPV--TRRRRKAFRRRVQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YVQQQ---DLH-LQT--STVREALKfsaylrqSNTTPDKEKDayvdyIIDLLEMseyadamVGVAGS-----------Gl 987
Cdd:COG1124 83 MVFQDpyaSLHpRHTvdRILAEPLR-------IHGLPDREER-----IAELLEQ-------VGLPPSfldryphqlsgG- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 988 nieQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSALlltEF--DRLLFLQEG 1064
Cdd:COG1124 143 ---QRQRVAIARALILEPELLL-LDEPTSALDVSVQAEILNLLKDLrEERGLTYLFVSHDLAVV---AHlcDRVAVMQNG 215
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
860-1022 |
3.58e-17 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 82.59 E-value: 3.58e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsDRH---TVGVIT-DGVKMvngHSLDSSFQRS-IGYVqQQDLHLQ 934
Cdd:cd03249 15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLL-ERFydpTSGEILlDGVDI---RDLNLRWLRSqIGLV-SQEPVLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSAYLRQSNTTPDKEKDAYV-DYIIDLleMSEYaDAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:cd03249 90 DGTIAENIRYGKPDATDEEVEEAAKKANIhDFIMSL--PDGY-DTLVGERGSQLSGGQKQRIAIARALLRNPKILL-LDE 165
|
....*....
gi 344304674 1014 PTSGLDSQT 1022
Cdd:cd03249 166 ATSALDAES 174
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
863-1045 |
4.55e-17 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 80.93 E-value: 4.55e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSS------FQRSIGYV-QQQDLHL 933
Cdd:TIGR01166 7 VLKGLNFAAERGEVLALLGANGAGKSTLLLHLN-----GLLrpQSGAVLIDGEPLDYSrkglleRRQRVGLVfQDPDDQL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKFSayLRQSNTTPDkEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:TIGR01166 82 FAADVDQDVAFG--PLNLGLSEA-EVERRVREALTAVGASGLRERPTHCLSGG----EKKRVAIAGAVAMRPDVLL-LDE 153
|
170 180 190
....*....|....*....|....*....|..
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:TIGR01166 154 PTAGLDPAGREQMLAILRRLRAEGMTVVISTH 185
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
871-1064 |
4.90e-17 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 81.87 E-value: 4.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLsdrhtVGVI--TDGVKMVNGHSLD----SSFQRSIGYVqQQDLHLQTSTVREALKF 944
Cdd:cd03245 27 IRAGEKVAIIGRVGSGKSTLLKLL-----AGLYkpTSGSVLLDGTDIRqldpADLRRNIGYV-PQDVTLFYGTLRDNITL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 945 SAylrqsnttPDKEkDAYVDYIIDLLEMSEYA-------DAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:cd03245 101 GA--------PLAD-DERILRAAELAGVTDFVnkhpnglDLQIGERGRGLSGGQRQAVALARALLNDPPILL-LDEPTSA 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 344304674 1018 LDSQTAWSICKLMRKLADHGQAILCTiHQPSALLLTefDRLLFLQEG 1064
Cdd:cd03245 171 MDMNSEERLKERLRQLLGDKTLIIIT-HRPSLLDLV--DRIIVMDSG 214
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
858-1064 |
1.35e-16 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 80.48 E-value: 1.35e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 858 KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLN--CLSDRHTVGVItdgvkMVNGHSLDS-------SFQRSIGYVqQ 928
Cdd:COG2884 12 PGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKllYGEERPTSGQV-----LVNGQDLSRlkrreipYLRRRIGVV-F 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 929 QDLHLQTS-TVREALKFSayLRQSNTTPDKEKDAyVDYIIDLLEMSEYADAMVGVagsgLNIEQRKRLTIGVELVAKPKL 1007
Cdd:COG2884 86 QDFRLLPDrTVYENVALP--LRVTGKSRKEIRRR-VREVLDLVGLSDKAKALPHE----LSGGEQQRVAIARALVNRPEL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1008 LLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSalLLTEFD-RLLFLQEG 1064
Cdd:COG2884 159 LL-ADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLE--LVDRMPkRVLELEDG 213
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
864-1064 |
1.58e-16 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 80.85 E-value: 1.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITDGVKMVNGHSLDssfQRSIGYVQQQDLHLQTSTVREA 941
Cdd:cd03296 18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAglERPDSGTILFGGEDATDVPVQ---ERNVGFVFQHYALFRHMTVFDN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 942 LKFSAYLRQSNTTPDK-EKDAYVDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDS 1020
Cdd:cd03296 95 VAFGLRVKPRSERPPEaEIRAKVHELLKLVQLDWLADRY----PAQLSGGQRQRVALARALAVEPKVLL-LDEPFGALDA 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 344304674 1021 QTAWSICKLMRKLAD--HGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:cd03296 170 KVRKELRRWLRRLHDelHVTTVFVTHDQEEALEVA--DRVVVMNKG 213
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
871-1143 |
1.58e-16 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 86.22 E-value: 1.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSL---DSSFQRSIGYVQQQDLHLQTSTVREALKFSAY 947
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGDTTV---TSGDATVAGKSIltnISDVHQNMGYCPQFDAIDDLLTGREHLYLYAR 2038
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 948 LRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSIC 1027
Cdd:TIGR01257 2039 LR---GVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGG----NKRKLSTAIALIGCPPLVL-LDEPTTGMDPQARRMLW 2110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1028 KLMRKLADHGQAILCTIH--QPSALLLTefdRLLFLQEGGqtvyFGDLGencqTLINYFEKYG------------ADACP 1093
Cdd:TIGR01257 2111 NTIVSIIREGRAVVLTSHsmEECEALCT---RLAIMVKGA----FQCLG----TIQHLKSKFGdgyivtmkikspKDDLL 2179
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1094 KDANPAEWMLKvvGAAPGS-----HAEADYFQVWRKS-----------------EEYNEIQSELDKMEVELA 1143
Cdd:TIGR01257 2180 PDLNPVEQFFQ--GNFPGSvqrerHYNMLQFQVSSSSlarifqllishkdslliEEYSVTQTTLDQVFVNFA 2249
|
|
| ABC_trans_N |
pfam14510 |
ABC-transporter N-terminal; This domain is found at the N-terminus of ABC-transporter proteins ... |
34-131 |
1.81e-16 |
|
ABC-transporter N-terminal; This domain is found at the N-terminus of ABC-transporter proteins from fungi, plants to higher eukaryotes. It is predicted to be an intracellular domain.
Pssm-ID: 464194 Cd Length: 80 Bit Score: 75.43 E-value: 1.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 34 QLARKITQdyatsdQSSSVPYLSSNDvvpainpyqdeltGSNLDPESPKFDSKYWIKNLKALYQSDPdYFKPNKLGVAFR 113
Cdd:pfam14510 1 ELARILTR------QSSSSSSSSSPE-------------STDPDEEDSEFDLRKWLKNLRRLIDEDG-YIKPRKLGVAFK 60
|
90
....*....|....*...
gi 344304674 114 DLRAYGIANDFDYQTTVA 131
Cdd:pfam14510 61 NLTVSGVGAGADYQPTVG 78
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
156-373 |
1.92e-16 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 79.21 E-value: 1.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVNTYGFQVDKDSKVsyDGLtpdEIEKHYRGDVIYSAETDEHFPQLTV 235
Cdd:cd03232 22 LLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGVITGEILI--NGR---PLDKNFQRSTGYVEQQDVHSPNLTV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 GDTLEFAARLrtpqnRGLGVDretyakhmasvymatygilrqrntpvgnefvpgcsggERKRVSIAeVSLSgAN--IQCW 313
Cdd:cd03232 97 REALRFSALL-----RGLSVE-------------------------------------QRKRLTIG-VELA-AKpsILFL 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 314 DNATRGLDAATALEFIRALK----TSSAVLdvtpvIAIYQCSQDAYDLFDNVSVLY-GGHQIFFG 373
Cdd:cd03232 133 DEPTSGLDSQAAYNIVRFLKkladSGQAIL-----CTIHQPSASIFEKFDRLLLLKrGGKTVYFG 192
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
863-1041 |
2.39e-16 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 80.03 E-value: 2.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVITdgvkmVNGHSLD--SSFQRS---IGYVQQ-----QD 930
Cdd:COG0410 18 VLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGllPPRSGSIR-----FDGEDITglPPHRIArlgIGYVPEgrrifPS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 LhlqtsTVREALKFSAYLRQSNTTPDKEkdayVDYIIDL---LEmsEYADAMvgvAG--SGlniEQRKRLTIGVELVAKP 1005
Cdd:COG0410 93 L-----TVEENLLLGAYARRDRAEVRAD----LERVYELfprLK--ERRRQR---AGtlSG---GEQQMLAIGRALMSRP 155
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 344304674 1006 KLLLfLDEPTSGLdsqtAWSICKLM----RKLADHGQAIL 1041
Cdd:COG0410 156 KLLL-LDEPSLGL----APLIVEEIfeiiRRLNREGVTIL 190
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
853-1019 |
3.04e-16 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 79.06 E-value: 3.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLDS--SFQRSIGYVQQQD 930
Cdd:COG4136 6 NLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFSASGEVLLNGRRLTAlpAEQRRIGILFQDD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 L---HLqtsTVREALKFSAylrqSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKL 1007
Cdd:COG4136 86 LlfpHL---SVGENLAFAL----PPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGG----QRARVALLRALLAEPRA 154
|
170
....*....|..
gi 344304674 1008 LLfLDEPTSGLD 1019
Cdd:COG4136 155 LL-LDEPFSKLD 165
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
863-1068 |
6.63e-16 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 78.98 E-value: 6.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVG---VITDGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVR 939
Cdd:PRK09493 16 VLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITsgdLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFSAYLRQSNTTPDKEKDAyvdyiIDLLemseyadAMVGVAG------SGLNIEQRKRLTIGVELVAKPKLLLFlDE 1013
Cdd:PRK09493 96 ENVMFGPLRVRGASKEEAEKQA-----RELL-------AKVGLAErahhypSELSGGQQQRVAIARALAVKPKLMLF-DE 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHQpsalllTEF-----DRLLFLQEGGQTV 1068
Cdd:PRK09493 163 PTSALDPELRHEVLKVMQDLAEEGMTMVIVTHE------IGFaekvaSRLIFIDKGRIAE 216
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
853-1075 |
6.99e-16 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 80.92 E-value: 6.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIKKE-DRIILDhVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSL-DSSF-------QR 921
Cdd:COG4148 4 EVDFRLRrGGFTLD-VDFTLPGRGVTALFGPSGSGKTTLLRAIAglERPDSGRIR-----LGGEVLqDSARgiflpphRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYVQQQDL---HLqtsTVREALKFsAYLRqsntTPDKEKDAYVDYIIDLLEMSEYADAMVGvAGSGlniEQRKRLTIG 998
Cdd:COG4148 78 RIGYVFQEARlfpHL---SVRGNLLY-GRKR----APRAERRISFDEVVELLGIGHLLDRRPA-TLSG---GERQRVAIG 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 999 VELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQ-AILCTIHQPS-ALLLTefDRLLFLqEGGQTVYFGDLGE 1075
Cdd:COG4148 146 RALLSSPRLLL-MDEPLAALDLARKAEILPYLERLRDELDiPILYVSHSLDeVARLA--DHVVLL-EQGRVVASGPLAE 220
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
864-1045 |
1.10e-15 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 77.45 E-value: 1.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLDS-------SFQRSIGYVQQQDLHLQTS 936
Cdd:cd03292 17 LDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELP---TSGTIRVNGQDVSDlrgraipYLRRKIGVVFQDFRLLPDR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKFSayLRQSNTTPdKEKDAYVDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:cd03292 94 NVYENVAFA--LEVTGVPP-REIRKRVPAALELVGLSHKHRAL----PAELSGGEQQRVAIARAIVNSPTILI-ADEPTG 165
|
170 180
....*....|....*....|....*....
gi 344304674 1017 GLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:cd03292 166 NLDPDTTWEIMNLLKKINKAGTTVVVATH 194
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
860-1047 |
1.94e-15 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 81.25 E-value: 1.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS---DRHTVGVITDGVKMvngHSLDSSFQRSIGYVQQQDLHLQTS 936
Cdd:TIGR02868 347 APPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAgllDPLQGEVTLDGVPV---SSLDQDEVRRRVSVCAQDAHLFDT 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKFSAylrqSNTTPDKEKDAY--VDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:TIGR02868 424 TVRENLRLAR----PDATDEELWAALerVGLADWLRALPDGLDTVLGEGGARLSGGERQRLALARALLADAPILL-LDEP 498
|
170 180 190
....*....|....*....|....*....|...
gi 344304674 1015 TSGLDSQTAWSICKLMRKlADHGQAILCTIHQP 1047
Cdd:TIGR02868 499 TEHLDAETADELLEDLLA-ALSGRTVVLITHHL 530
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
848-1035 |
3.72e-15 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 76.45 E-value: 3.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL-------SDRHTVG-VITDGVKMVNGHSLDSSF 919
Cdd:cd03260 4 RDLNVYYG----DKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlndliPGAPDEGeVLLDGKDIYDLDVDVLEL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 920 QRSIGYVQQQDLHLQTStVREALKFSAYLRQSNttPDKEKDAYVDyiiDLLEMS----EYADAMVGVAGSGlniEQRKRL 995
Cdd:cd03260 80 RRRVGMVFQKPNPFPGS-IYDNVAYGLRLHGIK--LKEELDERVE---EALRKAalwdEVKDRLHALGLSG---GQQQRL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAD 1035
Cdd:cd03260 151 CLARALANEPEVLL-LDEPTSALDPISTAKIEELIAELKK 189
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
829-1045 |
4.34e-15 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 76.60 E-value: 4.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 829 EIVELSENGLTGENETFLWRDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDG 906
Cdd:cd03267 2 EVSNLSKSYRVYSKEPGLIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILS-----GLLqpTSG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 907 VKMVNG---HSLDSSFQRSIGYV--QQQDLHLQTStVREALKFsayLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVg 981
Cdd:cd03267 77 EVRVAGlvpWKRRKKFLRRIGVVfgQKTQLWWDLP-VIDSFYL---LAAIYDLPPARFKKRLDELSELLDLEELLDTPV- 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 982 vagSGLNIEQRKRLTIGVELVAKPKlLLFLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIH 1045
Cdd:cd03267 152 ---RQLSLGQRMRAEIAAALLHEPE-ILFLDEPTIGLDVVAQENIRNFLKEYnRERGTTVLLTSH 212
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
855-1045 |
4.72e-15 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 76.04 E-value: 4.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 855 RIKKedRIILDHVDGWVKPGEITALMGATGAGKTTLLNClsdrhTVGVI--TDGVKMVNGHSLDSS--FQRS---IGYVQ 927
Cdd:cd03218 9 RYGK--RKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYM-----IVGLVkpDSGKILLDGQDITKLpmHKRArlgIGYLP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 928 QQDLHLQTSTVREALkfSAYLRQSnTTPDKEKDAYVDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKL 1007
Cdd:cd03218 82 QEASIFRKLTVEENI--LAVLEIR-GLSKKEREEKLEELLEEFHITHLRKSK----ASSLSGGERRRVEIARALATNPKF 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 344304674 1008 LLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:cd03218 155 LL-LDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDH 191
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
860-1058 |
8.36e-15 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 77.15 E-value: 8.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGVITD--GVKMVNGHSLDSSFQRS---IGYVQQQDLHLQ 934
Cdd:PRK13537 19 DKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRML-----LGLTHPdaGSISLCGEPVPSRARHArqrVGVVPQFDNLDP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALK-FSAYLRQSNTTPDkekdAYVDYIIDLLEMSEYADAMVGVAGSGLnieqRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:PRK13537 94 DFTVRENLLvFGRYFGLSAAAAR----ALVPPLLEFAKLENKADAKVGELSGGM----KRRLTLARALVNDPDVLV-LDE 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHqpsalLLTEFDRL 1058
Cdd:PRK13537 165 PTTGLDPQARHLMWERLRSLLARGKTILLTTH-----FMEEAERL 204
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
848-1033 |
8.49e-15 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 77.43 E-value: 8.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMVnghSLDSS----FQ 920
Cdd:COG1135 5 ENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINllERPTSGSVLvDGVDLT---ALSERelraAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 RSIGYVQQQDLHLQTSTVRE--ALKfsayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADA----MvgvagSGlniEQRKR 994
Cdd:COG1135 82 RKIGMIFQHFNLLSSRTVAEnvALP----LEIAG-VPKAEIRKRVAELLELVGLSDKADAypsqL-----SG---GQKQR 148
|
170 180 190
....*....|....*....|....*....|....*....
gi 344304674 995 LTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 1033
Cdd:COG1135 149 VGIARALANNPKVLL-CDEATSALDPETTRSILDLLKDI 186
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
860-1019 |
1.51e-14 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 77.06 E-value: 1.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSLDS--SFQRSIGYVQQQDL---H 932
Cdd:COG3842 17 DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAgfETPDSGRIL-----LDGRDVTGlpPEKRNVGMVFQDYAlfpH 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 933 LqtsTVREALKFSayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADAMVGvAGSGlniEQRKRLTIGVELVAKPKLLLfLD 1012
Cdd:COG3842 92 L---TVAENVAFG--LRMRG-VPKAEIRARVAELLELVGLEGLADRYPH-QLSG---GQQQRVALARALAPEPRVLL-LD 160
|
....*..
gi 344304674 1013 EPTSGLD 1019
Cdd:COG3842 161 EPLSALD 167
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
848-1064 |
2.73e-14 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 74.38 E-value: 2.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvgvITDGVKMVNGHSLDS------SFQR 921
Cdd:COG4559 5 ENLSVRLG----GRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELT---PSSGEVRLNGRPLAAwspwelARRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SigyVQQQDLHLQTS-TVREALKFSAYLRQSNTTPDKEkdayvdyIIDllemseyaDAM--VGVAG---------SGLni 989
Cdd:COG4559 78 A---VLPQHSSLAFPfTVEEVVALGRAPHGSSAAQDRQ-------IVR--------EALalVGLAHlagrsyqtlSGG-- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 990 EQRKrltigVEL----------VAKPKLLLFLDEPTSGLD----SQTAwsicKLMRKLADHGQAILCTIHQpsaLLLT-E 1054
Cdd:COG4559 138 EQQR-----VQLarvlaqlwepVDGGPRWLFLDEPTSALDlahqHAVL----RLARQLARRGGGVVAVLHD---LNLAaQ 205
|
250
....*....|.
gi 344304674 1055 F-DRLLFLQEG 1064
Cdd:COG4559 206 YaDRILLLHQG 216
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
860-1090 |
7.80e-14 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 74.48 E-value: 7.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL-----SDRHTVGVITDGVKmvnghSLDSSFQRSIGYVQQQDLHLQ 934
Cdd:PRK13536 53 DKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMIlgmtsPDAGKITVLGVPVP-----ARARLARARIGVVPQFDNLDL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREAL-KFSAYLRQSNttpdKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLnieqRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:PRK13536 128 EFTVRENLlVFGRYFGMST----REIEAVIPSLLEFARLESKADARVSDLSGGM----KRRLTLARALINDPQLLI-LDE 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1014 PTSGLDSQTAWSICKLMRKLADHGQAILCTIHqpsalLLTEFDRL---LFLQEGGQTVYFGDLGENCQTLI--NYFEKYG 1088
Cdd:PRK13536 199 PTTGLDPHARHLIWERLRSLLARGKTILLTTH-----FMEEAERLcdrLCVLEAGRKIAEGRPHALIDEHIgcQVIEIYG 273
|
..
gi 344304674 1089 AD 1090
Cdd:PRK13536 274 GD 275
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
860-1064 |
1.15e-13 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 72.26 E-value: 1.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLD----SSFQRSIGYVQQqDLHLQT 935
Cdd:cd03253 13 GRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDV---SSGSILIDGQDIRevtlDSLRRAIGVVPQ-DTVLFN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKfsaYLRQSNTTPDKEKDAYVDYIID-LLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPkLLLFLDEP 1014
Cdd:cd03253 89 DTIGYNIR---YGRPDATDEEVIEAAKAAQIHDkIMRFPDGYDTIVGERGLKLSGGEKQRVAIARAILKNP-PILLLDEA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 344304674 1015 TSGLDSQTAWSICKLMRKLADHGQAILCTiHQPSAllLTEFDRLLFLQEG 1064
Cdd:cd03253 165 TSALDTHTEREIQAALRDVSKGRTTIVIA-HRLST--IVNADKIIVLKDG 211
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
860-1019 |
2.52e-13 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 73.18 E-value: 2.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGvKMVNGhsLDSSfQRSIGYV-QQQDL--HL 933
Cdd:COG3839 15 GVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAglEDPTSGEILiGG-RDVTD--LPPK-DRNIAMVfQSYALypHM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 qtsTVREALKFSayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADAMVGvAGSGlniEQRKRLTIGVELVAKPKLLLFlDE 1013
Cdd:COG3839 91 ---TVYENIAFP--LKLRK-VPKAEIDRRVREAAELLGLEDLLDRKPK-QLSG---GQRQRVALGRALVREPKVFLL-DE 159
|
....*.
gi 344304674 1014 PTSGLD 1019
Cdd:COG3839 160 PLSNLD 165
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
860-1046 |
2.93e-13 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 72.06 E-value: 2.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDSSFQRSIGYvqqqdlhL---- 933
Cdd:COG4152 13 DKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTI-----RIILGILapDSGEVLWDGEPLDPEDRRRIGY-------Lpeer 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 ---QTSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAmvgvagsglNIE------QRKrLTIGVELVAK 1004
Cdd:COG4152 81 glyPKMKVGEQLVYLARLKG---LSKAEAKRRADEWLERLGLGDRANK---------KVEelskgnQQK-VQLIAALLHD 147
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 344304674 1005 PKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQ 1046
Cdd:COG4152 148 PELLI-LDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQ 188
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
164-371 |
4.25e-13 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 70.66 E-value: 4.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFqVDKDS-KVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLEFA 242
Cdd:COG4555 24 AKDGEITGLLGPNGAGKTTLLRMLA----GL-LKPDSgSILIDGEDVRKEPREARRQIGVLPDERGLYDRLTVRENIRYF 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 243 ARLRtpqnrglGVDRETYAKHMASvYMATYGILRQRNTPVGnEFvpgcSGGERKRVSIAEVSLSGANIQCWDNATRGLDA 322
Cdd:COG4555 99 AELY-------GLFDEELKKRIEE-LIELLGLEEFLDRRVG-EL----STGMKKKVALARALVHDPKVLLLDEPTNGLDV 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 344304674 323 ATA---LEFIRALKTS-SAVLDVTPVIaiyqcsQDAYDLFDNVSVLYGGHQIF 371
Cdd:COG4555 166 MARrllREILRALKKEgKTVLFSSHIM------QEVEALCDRVVILHKGKVVA 212
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
871-1064 |
7.64e-13 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 69.04 E-value: 7.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLsdrhtVGVITdgvkMVNGHsldSSFQRSIGYVQQQDLhLQTSTVREALKFSAYLrq 950
Cdd:cd03250 28 VPKGELVAIVGPVGSGKSSLLSAL-----LGELE----KLSGS---VSVPGSIAYVSQEPW-IQNGTIRENILFGKPF-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 951 snttpDKEKdaYvDYIIDL------LEMSEYADA-MVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTA 1023
Cdd:cd03250 93 -----DEER--Y-EKVIKAcalepdLEILPDGDLtEIGEKGINLSGGQKQRISLARAVYSDADIYL-LDDPLSAVDAHVG 163
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 344304674 1024 WSICK--LMRKLADHGQAILCTiHQPSalLLTEFDRLLFLQEG 1064
Cdd:cd03250 164 RHIFEncILGLLLNNKTRILVT-HQLQ--LLPHADQIVVLDNG 203
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
865-1064 |
8.66e-13 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 70.02 E-value: 8.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 865 DHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVITDGVKMVNG--------HSLDSSFQ-----RSIGYVQQ- 928
Cdd:PRK11300 22 NNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGfyKPTGGTILLRGQHIEGlpghqiarMGVVRTFQhvrlfREMTVIENl 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 929 ---QDLHLQTSTVREALKFSAYlRQSnttpDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKP 1005
Cdd:PRK11300 102 lvaQHQQLKTGLFSGLLKTPAF-RRA----ESEALDRAATWLERVGLLEHANRQAGNLAYG----QQRRLEIARCMVTQP 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1006 KLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:PRK11300 173 EILM-LDEPAAGLNPKETKELDELIAELRNeHNVTVLLIEHDMK-LVMGISDRIYVVNQG 230
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
854-1064 |
1.11e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 72.57 E-value: 1.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRIILDHvDGWV---------KPGEITALMGATGAGKTTLLNCLSdrhtvGVIT-DGVKMVNG---HSLD-SSF 919
Cdd:PRK11174 348 VTIEAEDLEILSP-DGKTlagplnftlPAGQRIALVGPSGAGKTSLLNALL-----GFLPyQGSLKINGielRELDpESW 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 920 QRSIGYVqQQDLHLQTSTVREALKfsayLRQSNTTPDK----EKDAYVDYIIDLLEMSeyADAMVGVAGSGLNIEQRKRL 995
Cdd:PRK11174 422 RKHLSWV-GQNPQLPHGTLRDNVL----LGNPDASDEQlqqaLENAWVSEFLPLLPQG--LDTPIGDQAAGLSVGQAQRL 494
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQtawSICKLMRKL--ADHGQAILCTIHQPSAllLTEFDRLLFLQEG 1064
Cdd:PRK11174 495 ALARALLQPCQLLL-LDEPTASLDAH---SEQLVMQALnaASRRQTTLMVTHQLED--LAQWDQIWVMQDG 559
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
864-1033 |
1.93e-12 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 70.21 E-value: 1.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNC--LSDRHTVG-VITDGVKMVnghSLDSS----FQRSIGYVQQqdlH---L 933
Cdd:PRK11153 21 LNNVSLHIPAGEIFGVIGASGAGKSTLIRCinLLERPTSGrVLVDGQDLT---ALSEKelrkARRQIGMIFQ---HfnlL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKFSayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKLLLfLDE 1013
Cdd:PRK11153 95 SSRTVFDNVALP--LELAG-TPKAEIKARVTELLELVGLSDKADRY----PAQLSGGQKQRVAIARALASNPKVLL-CDE 166
|
170 180
....*....|....*....|
gi 344304674 1014 PTSGLDSQTAWSICKLMRKL 1033
Cdd:PRK11153 167 ATSALDPATTRSILELLKDI 186
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
835-1087 |
1.95e-12 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 70.12 E-value: 1.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 835 ENGLTGENETFLWRdltyEIRIKKEdriiLDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNG 912
Cdd:COG4586 17 EPGLKGALKGLFRR----EYREVEA----VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLT-----GILvpTSGEVRVLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 913 HS---LDSSFQRSIGYV--Q-QQ---DLhlqtsTVREALKfsaYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMV--- 980
Cdd:COG4586 84 YVpfkRRKEFARRIGVVfgQrSQlwwDL-----PAIDSFR---LLKAIYRIPDAEYKKRLDELVELLDLGELLDTPVrql 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 981 --GvagsglnieQRKRltigVELVA----KPKlLLFLDEPTSGLD--SQTAwsICKLMRKL-ADHGQAILCTIHQPS--- 1048
Cdd:COG4586 156 slG---------QRMR----CELAAallhRPK-ILFLDEPTIGLDvvSKEA--IREFLKEYnRERGTTILLTSHDMDdie 219
|
250 260 270
....*....|....*....|....*....|....*....
gi 344304674 1049 ALLltefDRLLFLQEgGQTVYFGDLGEncqtLINYFEKY 1087
Cdd:COG4586 220 ALC----DRVIVIDH-GRIIYDGSLEE----LKERFGPY 249
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
848-1066 |
1.96e-12 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 66.86 E-value: 1.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYeiRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVIT-DGVKMvngHSLDSS-FQRSI 923
Cdd:cd03246 4 ENVSF--RYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGllRPTSGRVRlDGADI---SQWDPNeLGDHV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 924 GYVQQQDLhLQTSTVREALkFSAylrqsnttpdkekdayvdyiidllemseyadamvgvagsGlnieQRKRLTIGVELVA 1003
Cdd:cd03246 79 GYLPQDDE-LFSGSIAENI-LSG---------------------------------------G----QRQRLGLARALYG 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1004 KPKLLlFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSalLLTEFDRLLFLQEGGQ 1066
Cdd:cd03246 114 NPRIL-VLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPE--TLASADRILVLEDGRV 173
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
855-1046 |
2.24e-12 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 68.42 E-value: 2.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 855 RIKKE--DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLDS--SFQRSIGYV-QQQ 929
Cdd:cd03300 5 NVSKFygGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETP---TSGEILLDGKDITNlpPHKRPVNTVfQNY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 930 DL--HLqtsTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVgvagSGLNIEQRKRLTIGVELVAKPKL 1007
Cdd:cd03300 82 ALfpHL---TVFENIAFGLRLKK---LPKAEIKERVAEALDLVQLEGYANRKP----SQLSGGQQQRVAIARALVNEPKV 151
|
170 180 190
....*....|....*....|....*....|....*....
gi 344304674 1008 LLfLDEPTSGLDsqtawsicklmRKLADHGQAILCTIHQ 1046
Cdd:cd03300 152 LL-LDEPLGALD-----------LKLRKDMQLELKRLQK 178
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
860-1045 |
4.92e-12 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 67.73 E-value: 4.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHT--VGVITDGVKMVNGHSlDSSFQRSIGYVQQQDLHLQTST 937
Cdd:PRK11231 14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTpqSGTVFLGDKPISMLS-SRQLARRLALLPQHHLTPEGIT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 938 VREALKF--SAYLRQSNTTPDKEKdAYVDYIIDLLEMSEYADAMVgvagSGLNIEQRKRLTIGVELvAKPKLLLFLDEPT 1015
Cdd:PRK11231 93 VRELVAYgrSPWLSLWGRLSAEDN-ARVNQAMEQTRINHLADRRL----TDLSGGQRQRAFLAMVL-AQDTPVVLLDEPT 166
|
170 180 190
....*....|....*....|....*....|
gi 344304674 1016 SGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:PRK11231 167 TYLDINHQVELMRLMRELNTQGKTVVTVLH 196
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
864-1041 |
5.49e-12 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 70.05 E-value: 5.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKMVNGHSLDsSFQRSIGYVqQQDLHL-QTSTVR 939
Cdd:COG1129 20 LDGVSLELRPGEVHALLGENGAGKSTLMKILSgvYQPDSGEILlDGEPVRFRSPRD-AQAAGIAII-HQELNLvPNLSVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFSAYLRQSNTTPDKE--KDAyvDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:COG1129 98 ENIFLGREPRRGGLIDWRAmrRRA--RELLARLGLDIDPDTPVG----DLSVAQQQLVEIARALSRDARVLI-LDEPTAS 170
|
170 180
....*....|....*....|....
gi 344304674 1018 LDSQTAWSICKLMRKLADHGQAIL 1041
Cdd:COG1129 171 LTEREVERLFRIIRRLKAQGVAII 194
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
864-1041 |
6.51e-12 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 65.14 E-value: 6.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVIT-DGvKMVNGHSLDSSFQRSIGYVQQqdlhlqtstvre 940
Cdd:cd03216 16 LDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYkpDSGEILvDG-KEVSFASPRDARRAGIAMVYQ------------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 alkfsaylrqsnttpdkekdayvdyiidllemseyadamvgvagsgLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDS 1020
Cdd:cd03216 83 ----------------------------------------------LSVGERQMVEIARALARNARLLI-LDEPTAALTP 115
|
170 180
....*....|....*....|.
gi 344304674 1021 QTAWSICKLMRKLADHGQAIL 1041
Cdd:cd03216 116 AEVERLFKVIRRLRAQGVAVI 136
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
861-1045 |
9.06e-12 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 66.84 E-value: 9.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 861 RIILDHVDGWVKPGEITALMGATGAGKTTLLNCL-----SDRHTVGVITDGVKMVNGHsldSSFQRSIGYVQQQDLHLQT 935
Cdd:PRK10895 16 RRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVvgivpRDAGNIIIDDEDISLLPLH---ARARRGIGYLPQEASIFRR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAYLRQSNTTPDKEKDAyvDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPT 1015
Cdd:PRK10895 93 LSVYDNLMAVLQIRDDLSAEQREDRA--NELMEEFHIEHLRDSM----GQSLSGGERRRVEIARALAANPKFIL-LDEPF 165
|
170 180 190
....*....|....*....|....*....|
gi 344304674 1016 SGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:PRK10895 166 AGVDPISVIDIKRIIEHLRDSGLGVLITDH 195
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
864-1022 |
1.64e-11 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 68.83 E-value: 1.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVIT-DGVKmVNGHSLdSSFQRSIGYVQQQDLhLQTSTVRE 940
Cdd:PRK13657 351 VEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFdpQSGRILiDGTD-IRTVTR-ASLRRNIAVVFQDAG-LFNRSIED 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSaylRQSNTTPDKEKDAYVDYIIDLLEMSEYA-DAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:PRK13657 428 NIRVG---RPDATDEEMRAAAERAQAHDFIERKPDGyDTVVGERGRQLSGGERQRLAIARALLKDPPILI-LDEATSALD 503
|
...
gi 344304674 1020 SQT 1022
Cdd:PRK13657 504 VET 506
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
871-1064 |
1.77e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 66.80 E-value: 1.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSS------FQRSIGYV-QQQDLHLQTSTVREA 941
Cdd:PRK13636 29 IKKGEVTAILGGNGAGKSTLFQNLN-----GILkpSSGRILFDGKPIDYSrkglmkLRESVGMVfQDPDNQLFSASVYQD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 942 LKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAmvgvAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQ 1021
Cdd:PRK13636 104 VSFGAVNLK---LPEDEVRKRVDNALKRTGIEHLKDK----PTHCLSFGQKKRVAIAGVLVMEPKVLV-LDEPTAGLDPM 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 344304674 1022 TAWSICKLMRKLADH-GQAILCTIHQPSALLLTeFDRLLFLQEG 1064
Cdd:PRK13636 176 GVSEIMKLLVEMQKElGLTIIIATHDIDIVPLY-CDNVFVMKEG 218
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
848-1064 |
1.94e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 64.86 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIrikkEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGViTDGVKMVNGHSLDS---------- 917
Cdd:cd03217 4 KDLHVSV----GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEV-TEGEILFKGEDITDlppeerarlg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 918 ---SFQRSIGYvqqqdlhlqtstvrEALKFSAYLRqsnttpdkekdaYVDyiidllemseyadamVGVAGSglnieQRKR 994
Cdd:cd03217 79 iflAFQYPPEI--------------PGVKNADFLR------------YVN---------------EGFSGG-----EKKR 112
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 995 LTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLFLQEG 1064
Cdd:cd03217 113 NEILQLLLLEPDLAI-LDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDYIKPDRVHVLYDG 181
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
164-301 |
3.00e-11 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 64.76 E-value: 3.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG-----LTPDEIEKhyRGdVIYSAETDEHFPQLTVGDT 238
Cdd:cd03224 23 VPEGEIVALLGRNGAGKTTLLKTIM----GLLPPRSGSIRFDGrditgLPPHERAR--AG-IGYVPEGRRIFPELTVEEN 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344304674 239 LEFAARLRTPQNRGLGVDRetyakhmasVYmATYGILRQR-NTPVGNefvpgCSGGERKRVSIA 301
Cdd:cd03224 96 LLLGAYARRRAKRKARLER---------VY-ELFPRLKERrKQLAGT-----LSGGEQQMLAIA 144
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
848-1045 |
3.22e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 65.87 E-value: 3.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIrikKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDSS------F 919
Cdd:PRK13639 5 RDLKYSY---PDGTEALKGINFKAEKGEMVALLGPNGAGKSTLF-----LHFNGILkpTSGEVLIKGEPIKYDkkslleV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 920 QRSIGYV-QQQDLHLQTSTVREALKFSAYlrqSNTTPDKEKDAYVDYIIDLLEMSEYADAmvgvAGSGLNIEQRKRLTIG 998
Cdd:PRK13639 77 RKTVGIVfQNPDDQLFAPTVEEDVAFGPL---NLGLSKEEVEKRVKEALKAVGMEGFENK----PPHHLSGGQKKRVAIA 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 344304674 999 VELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:PRK13639 150 GILAMKPEIIV-LDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTH 195
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
855-1045 |
5.22e-11 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 64.28 E-value: 5.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 855 RIKKedRIILDHVDGWVKPGEITALMGATGAGKTTLLNClsdrhTVGVI--TDGVKMVNGHSL--DSSFQRS---IGYVQ 927
Cdd:COG1137 12 SYGK--RTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYM-----IVGLVkpDSGRIFLDGEDIthLPMHKRArlgIGYLP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 928 QQ-----DLhlqtsTVREALKfsAYLRQSNTTPdKEKDAYVDYIIDLLEMSEYADAMvGVAGSGlniEQRKRLTIGVELV 1002
Cdd:COG1137 85 QEasifrKL-----TVEDNIL--AVLELRKLSK-KEREERLEELLEEFGITHLRKSK-AYSLSG---GERRRVEIARALA 152
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 344304674 1003 AKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:COG1137 153 TNPKFIL-LDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDH 194
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
863-1045 |
6.05e-11 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 66.40 E-value: 6.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVITD--GVKMVNGHSLDSSFQRSIGYvqqqdlhlQTSTVRE 940
Cdd:PRK09536 18 VLDGVDLSVREGSLVGLVGPNGAGKTTLL-----RAINGTLTPtaGTVLVAGDDVEALSARAASR--------RVASVPQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 --ALKFSAYLRQS---NTTP--------DKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELV-AKPK 1006
Cdd:PRK09536 85 dtSLSFEFDVRQVvemGRTPhrsrfdtwTETDRAAVERAMERTGVAQFADRPVTSLSGG----ERQRVLLARALAqATPV 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 344304674 1007 LLlfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:PRK09536 161 LL--LDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIH 197
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
847-1064 |
7.05e-11 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 63.64 E-value: 7.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 847 WRDLTYEIRiKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvgvITDGVKMVNGHSLDSsfqrsigyV 926
Cdd:cd03248 14 FQNVTFAYP-TRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQ---PQGGQVLLDGKPISQ--------Y 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 927 QQQDLHLQTSTV-REALKFSAYLRQS-----NTTPDKE-----KDAYVDYIIDLLEMSEYADamVGVAGSGLNIEQRKRL 995
Cdd:cd03248 82 EHKYLHSKVSLVgQEPVLFARSLQDNiayglQSCSFECvkeaaQKAHAHSFISELASGYDTE--VGEKGSQLSGGQKQRV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKlADHGQAILCTIHQPSalLLTEFDRLLFLQEG 1064
Cdd:cd03248 160 AIARALIRNPQVLI-LDEATSALDAESEQQVQQALYD-WPERRTVLVIAHRLS--TVERADQILVLDGG 224
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
864-1033 |
7.83e-11 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 63.89 E-value: 7.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSLD--SSFQRSIGYVQQQDLHLQTSTVR 939
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIA-----GFIKpdSGKILLNGKDITnlPPEKRDISYVPQNYALFPHMTVY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFSAYLRqsnTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:cd03299 90 KNIAYGLKKR---KVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGG----EQQRVAIARALVVNPKILL-LDEPFSALD 161
|
170
....*....|....
gi 344304674 1020 SQTAWSICKLMRKL 1033
Cdd:cd03299 162 VRTKEKLREELKKI 175
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
844-1045 |
8.05e-11 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 64.42 E-value: 8.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 844 TFLWRDLTYEIrikkEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdRHTVGviTDGVKMVNGHSLDS----SF 919
Cdd:PRK10575 11 TFALRNVSFRV----PGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLG-RHQPP--SEGEILLDAQPLESwsskAF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 920 QRSIGYVQQQDLHLQTSTVREALKFSAY-----LRQSNTTpDKEKdayVDYIIDLLEMSEYADAMVGVAGSGlnieQRKR 994
Cdd:PRK10575 84 ARKVAYLPQQLPAAEGMTVRELVAIGRYpwhgaLGRFGAA-DREK---VEEAISLVGLKPLAHRLVDSLSGG----ERQR 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 344304674 995 LTIGVeLVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIH 1045
Cdd:PRK10575 156 AWIAM-LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSqERGLTVIAVLH 206
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
863-1064 |
8.34e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 66.39 E-value: 8.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdRH---TVGVITdgvkmVNGHSL----DSSFQRSIGYVQQQdLHLQT 935
Cdd:PRK11160 355 VLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLT-RAwdpQQGEIL-----LNGQPIadysEAALRQAISVVSQR-VHLFS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAylrqsnttPDKEKDAYVDYII-----DLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLf 1010
Cdd:PRK11160 428 ATLRDNLLLAA--------PNASDEALIEVLQqvgleKLLEDDKGLNAWLGEGGRQLSGGEQRRLGIARALLHDAPLLL- 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1011 LDEPTSGLDSQTAWSICKLMRKLADHGQAILCTiHQPSAllLTEFDRLLFLQEG 1064
Cdd:PRK11160 499 LDEPTEGLDAETERQILELLAEHAQNKTVLMIT-HRLTG--LEQFDRICVMDNG 549
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
871-1064 |
9.70e-11 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 66.67 E-value: 9.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTT---LLNCLSDRHTVGVITDGVKMV--NGHSLdssfQRSIGYVQQQDLhLQTSTVREALkfs 945
Cdd:TIGR00958 504 LHPGEVVALVGPSGSGKSTvaaLLQNLYQPTGGQVLLDGVPLVqyDHHYL----HRQVALVGQEPV-LFSGSVRENI--- 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 946 AY-LRQsntTPDKE-----KDAYVDYIIdlLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:TIGR00958 576 AYgLTD---TPDEEimaaaKAANAHDFI--MEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLI-LDEATSALD 649
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 344304674 1020 SQTAWSICKLMRKladHGQAILCTIHQPSalLLTEFDRLLFLQEG 1064
Cdd:TIGR00958 650 AECEQLLQESRSR---ASRTVLLIAHRLS--TVERADQILVLKKG 689
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
860-1024 |
9.72e-11 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 66.24 E-value: 9.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT--DGVKmvnghsldssfqrsIGYVQQQDLHLQT 935
Cdd:COG0488 10 GRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAgeLEPDSGEVSipKGLR--------------IGYLPQEPPLDDD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREA-----------LKFSAYLRQSNTTPDKEKDAYVDYIIDLLEMSEY-ADAMVGVAGSGLNIE------------- 990
Cdd:COG0488 76 LTVLDTvldgdaelralEAELEELEAKLAEPDEDLERLAELQEEFEALGGWeAEARAEEILSGLGFPeedldrpvselsg 155
|
170 180 190
....*....|....*....|....*....|....*.
gi 344304674 991 -QRKRLTIGVELVAKPKLLLfLDEPTSGLDSQT-AW 1024
Cdd:COG0488 156 gWRRRVALARALLSEPDLLL-LDEPTNHLDLESiEW 190
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
864-1021 |
1.01e-10 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 65.24 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVG-VITDGVKMvnghSLDSSFQRSIGYVQQQDLHLQTSTVRE 940
Cdd:PRK11607 35 VDDVSLTIYKGEIFALLGASGCGKSTLLRMLAgfEQPTAGqIMLDGVDL----SHVPPYQRPINMMFQSYALFPHMTVEQ 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSayLRQsNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDS 1020
Cdd:PRK11607 111 NIAFG--LKQ-DKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGG----QRQRVALARSLAKRPKLLL-LDEPMGALDK 182
|
.
gi 344304674 1021 Q 1021
Cdd:PRK11607 183 K 183
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
823-1064 |
1.14e-10 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 65.96 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 823 SDFEKKEIVELS-----ENGLTGENETF--LWRDLTYEIR-IKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL 894
Cdd:PRK09700 230 SDVSNDDIVRLMvgrelQNRFNAMKENVsnLAHETVFEVRnVTSRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCL 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 895 --SDRHTVG-VITDGVKMVNGHSLDSsFQRSIGYVqqqdlhlqTSTVREALKFSAY-LRQSNTTPDKEKDAYVDYIIDLL 970
Cdd:PRK09700 310 fgVDKRAGGeIRLNGKDISPRSPLDA-VKKGMAYI--------TESRRDNGFFPNFsIAQNMAISRSLKDGGYKGAMGLF 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 971 EMSE---YADAM-----VGVAGSGLNIEQ-----RKRLTIGVELVAKPKLLLFlDEPTSGLDSQTAWSICKLMRKLADHG 1037
Cdd:PRK09700 381 HEVDeqrTAENQrellaLKCHSVNQNITElsggnQQKVLISKWLCCCPEVIIF-DEPTRGIDVGAKAEIYKVMRQLADDG 459
|
250 260
....*....|....*....|....*....
gi 344304674 1038 QAILCTihqPSAL--LLTEFDRLLFLQEG 1064
Cdd:PRK09700 460 KVILMV---SSELpeIITVCDRIAVFCEG 485
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
848-1047 |
1.26e-10 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 62.38 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEirikKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVITDGVKMVngHSLDSSFQRSIGY 925
Cdd:TIGR01189 4 RNLACS----RGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGllRPDSGEVRWNGTPL--AEQRDEPHENILY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 926 VQQQDLHLQTSTVREALKFSAYLRQSnttpdkeKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKP 1005
Cdd:TIGR01189 78 LGHLPGLKPELSALENLHFWAAIHGG-------AQRTIEDALAAVGLTGFEDLPAAQLSAG----QQRRLALARLWLSRR 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 344304674 1006 KLLLfLDEPTSGLDSQtawSICKLMRKLADH---GQAILCTIHQP 1047
Cdd:TIGR01189 147 PLWI-LDEPTTALDKA---GVALLAGLLRAHlarGGIVLLTTHQD 187
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
853-1047 |
1.51e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.13 E-value: 1.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVItdgvkMVNGHSLD---SSFQRSIGYVQ 927
Cdd:cd03231 5 ELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAglSPPLAGRV-----LLNGGPLDfqrDSIARGLLYLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 928 QQDLHLQTSTVREALKFSAylrqsnttpDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKL 1007
Cdd:cd03231 80 HAPGIKTTLSVLENLRFWH---------ADHSDEQVEEALARVGLNGFEDRPVAQLSAG----QQRRVALARLLLSGRPL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 344304674 1008 LLfLDEPTSGLDSQtawSICKLMRKLADH---GQAILCTIHQP 1047
Cdd:cd03231 147 WI-LDEPTTALDKA---GVARFAEAMAGHcarGGMVVLTTHQD 185
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
164-332 |
2.45e-10 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 65.07 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEI-EKHYRGDVIYSAEtDEHFPQLTVGDTLEFA 242
Cdd:TIGR02868 358 LPPGERVAILGPSGSGKSTLLATLA----GLLDPLQGEVTLDGVPVSSLdQDEVRRRVSVCAQ-DAHLFDTTVRENLRLA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 243 arlrtpqnRGLGVDRETYAKhMASVYMATYgiLRQR----NTPVGnEFVPGCSGGERKRVSIAEVSLSGANIQCWDNATR 318
Cdd:TIGR02868 433 --------RPDATDEELWAA-LERVGLADW--LRALpdglDTVLG-EGGARLSGGERQRLALARALLADAPILLLDEPTE 500
|
170
....*....|....
gi 344304674 319 GLDAATALEFIRAL 332
Cdd:TIGR02868 501 HLDAETADELLEDL 514
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
859-1064 |
2.78e-10 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 61.89 E-value: 2.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGV--ITDGVKMVNGHSLD--SSFQRSIGYVQQQDLHLQ 934
Cdd:cd03301 11 GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTL-----RMIAGLeePTSGRIYIGGRDVTdlPPKDRDIAMVFQNYALYP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:cd03301 86 HMTVYDNIAFGLKLRK---VPKDEIDERVREVAELLQIEHLLDRKPKQLSGG----QRQRVALGRAIVREPKVFL-MDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 1015 TSGLDS----QTAWSICKLMRKLadhGQAILCTIH-QPSALLLTefDRLLFLQEG 1064
Cdd:cd03301 158 LSNLDAklrvQMRAELKRLQQRL---GTTTIYVTHdQVEAMTMA--DRIAVMNDG 207
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
156-368 |
3.39e-10 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 59.95 E-value: 3.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntygfqvdkdskvsydGLTpdeieKHYRGDVIYsaetdehfpqltv 235
Cdd:cd00267 14 ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIA-----------------GLL-----KPTSGEILI------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 gdtlefaarlrtpqnrgLGVDRETYAKHmasvymatygILRQRntpVGneFVPGCSGGERKRVSIAEVSLSGANIQCWDN 315
Cdd:cd00267 59 -----------------DGKDIAKLPLE----------ELRRR---IG--YVPQLSGGQRQRVALARALLLNPDLLLLDE 106
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 344304674 316 ATRGLDAATALEFIRALKTSSAvlDVTPVIAIYQCSQDAYDLFDNVSVLYGGH 368
Cdd:cd00267 107 PTSGLDPASRERLLELLRELAE--EGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
863-1064 |
3.48e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 61.72 E-value: 3.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDrhtvgvITDG----VKMVnGHSLDSSFQ--------RSIGYVQQQD 930
Cdd:PRK10584 25 ILTGVELVVKRGETIALIGESGSGKSTLLAILAG------LDDGssgeVSLV-GQPLHQMDEearaklraKHVGFVFQSF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 931 LHLQTSTVREALKFSAYLRQSNTTPDKEKdayvdyIIDLLE---MSEYADAMVGVAGSGlniEQrKRLTIGVELVAKPKl 1007
Cdd:PRK10584 98 MLIPTLNALENVELPALLRGESSRQSRNG------AKALLEqlgLGKRLDHLPAQLSGG---EQ-QRVALARAFNGRPD- 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1008 LLFLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSalLLTEFDRLLFLQEG 1064
Cdd:PRK10584 167 VLFADEPTGNLDRQTGDKIADLLFSLnREHGTTLILVTHDLQ--LAARCDRRLRLVNG 222
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
849-1046 |
3.52e-10 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 61.51 E-value: 3.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 849 DLTYEIRI------KKEDRI---ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHtvgvitdgvkmvnghsldsSF 919
Cdd:COG2401 22 DLSERVAIvleafgVELRVVeryVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGAL-------------------KG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 920 QRSIGYVQQQDLHL-QTSTVREALkfsaylrqsnttpDKEKDayVDYIIDLLEMSEYADAMVGVAG-SGLNIEQRKRLTI 997
Cdd:COG2401 83 TPVAGCVDVPDNQFgREASLIDAI-------------GRKGD--FKDAVELLNAVGLSDAVLWLRRfKELSTGQKFRFRL 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HG-QAILCTIHQ 1046
Cdd:COG2401 148 ALLLAERPKLLV-IDEFCSHLDRQTAKRVARNLQKLARrAGiTLVVATHHY 197
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
145-334 |
4.33e-10 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 60.94 E-value: 4.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 145 FRKDDKSRYfdILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG--LTPDEIEKHYR--GDV 220
Cdd:cd03225 7 FSYPDGARP--ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLN----GLLGPTSGEVLVDGkdLTKLSLKELRRkvGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 221 IYSAETdehfpQL---TVGDTLEFAarlrtPQNrgLGVDRETyAKHMASVYMATYGILRQRNTPVGNefvpgCSGGERKR 297
Cdd:cd03225 81 FQNPDD-----QFfgpTVEEEVAFG-----LEN--LGLPEEE-IEERVEEALELVGLEGLRDRSPFT-----LSGGQKQR 142
|
170 180 190
....*....|....*....|....*....|....*..
gi 344304674 298 VSIAEVSLSGANIQCWDNATRGLDAATALEFIRALKT 334
Cdd:cd03225 143 VAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKK 179
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
864-1075 |
4.41e-10 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 64.04 E-value: 4.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVITdgvkmVNGHSLDS-----SFQRSIGYVQQQDLHLQTS 936
Cdd:PRK09700 21 LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHepTKGTIT-----INNINYNKldhklAAQLGIGIIYQELSVIDEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALkfsaYLRQSNTtpdkEKDAYVDyIIDLLEMSEYADAMVGVAG---------SGLNIEQRKRLTIGVELVAKPKL 1007
Cdd:PRK09700 96 TVLENL----YIGRHLT----KKVCGVN-IIDWREMRVRAAMMLLRVGlkvdldekvANLSISHKQMLEIAKTLMLDAKV 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1008 LLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQpsallLTEF----DRLLFLQEgGQTVYFGDLGE 1075
Cdd:PRK09700 167 II-MDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHK-----LAEIrricDRYTVMKD-GSSVCSGMVSD 231
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
157-332 |
4.44e-10 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 64.23 E-value: 4.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 157 LKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEI-EKHYRGDVIYSAETdehfPQLTV 235
Cdd:TIGR02857 338 LRPVSFTVPPGERVALVGPSGAGKSTLLNLLL----GFVDPTEGSIAVNGVPLADAdADSWRDQIAWVPQH----PFLFA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 GdTLEFAARLRTPQNRGLGVDRetyAKHMASVYMATYGILRQRNTPVGnEFVPGCSGGERKRVSIAEVSLSGANIQCWDN 315
Cdd:TIGR02857 410 G-TIAENIRLARPDASDAEIRE---ALERAGLDEFVAALPQGLDTPIG-EGGAGLSGGQAQRLALARAFLRDAPLLLLDE 484
|
170
....*....|....*..
gi 344304674 316 ATRGLDAATALEFIRAL 332
Cdd:TIGR02857 485 PTAHLDAETEAEVLEAL 501
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
848-1064 |
5.52e-10 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 61.71 E-value: 5.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRikkeDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSLdSSFQRsigy 925
Cdd:PRK13548 6 RNLSVRLG----GRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALS-----GELSpdSGEVRLNGRPL-ADWSP---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 926 vQQQDLHL----QTS------TVREALKFSAYlrqSNTTPDKEKDAYVDYIIDLLEMSEYAD----AMVGvaGsglniEQ 991
Cdd:PRK13548 72 -AELARRRavlpQHSslsfpfTVEEVVAMGRA---PHGLSRAEDDALVAAALAQVDLAHLAGrdypQLSG--G-----EQ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 992 RKrltigVEL---------VAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQpsaLLLTEF--DRLL 1059
Cdd:PRK13548 141 QR-----VQLarvlaqlwePDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAhERGLAVIVVLHD---LNLAARyaDRIV 212
|
....*
gi 344304674 1060 FLQEG 1064
Cdd:PRK13548 213 LLHQG 217
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
863-1064 |
7.10e-10 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 60.59 E-value: 7.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCL---SDRhTVGVIT-DGVKM--VNGHSLdssfQRSIGYVqQQDLHLQTS 936
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALfrlVEL-SSGSILiDGVDIskIGLHDL----RSRISII-PQDPVLFSG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALK-FSAYlrqsnttPDKEkdayvdyIIDLLEMS---EYADAMVG-----VAGSGLNIE--QRKRLTIGVELVAKP 1005
Cdd:cd03244 93 TIRSNLDpFGEY-------SDEE-------LWQALERVglkEFVESLPGgldtvVEEGGENLSvgQRQLLCLARALLRKS 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1006 KLLLfLDEPTSGLDSQTAWSICKLMR-KLADHgqAILCTIHQPSALLltEFDRLLFLQEG 1064
Cdd:cd03244 159 KILV-LDEATASVDPETDALIQKTIReAFKDC--TVLTIAHRLDTII--DSDRILVLDKG 213
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
871-1061 |
7.41e-10 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 59.75 E-value: 7.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT-DGVKmVNGHSLDSSFQRSIGYV----QQQDLHLQTStVREALK 943
Cdd:cd03215 23 VRAGEIVGIAGLVGNGQTELAEALFglRPPASGEITlDGKP-VTRRSPRDAIRAGIAYVpedrKREGLVLDLS-VAENIA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 944 FSAYLrqsnttpdkekdayvdyiidllemseyadamvgvagSGLNieQRKrLTIGVELVAKPKLLLfLDEPTSGLDSQTA 1023
Cdd:cd03215 101 LSSLL------------------------------------SGGN--QQK-VVLARWLARDPRVLI-LDEPTRGVDVGAK 140
|
170 180 190
....*....|....*....|....*....|....*...
gi 344304674 1024 WSICKLMRKLADHGQAILctihqpsaLLLTEFDRLLFL 1061
Cdd:cd03215 141 AEIYRLIRELADAGKAVL--------LISSELDELLGL 170
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
156-333 |
9.06e-10 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 60.87 E-value: 9.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPdeieKHYRGDVIY---SAETDEHFPq 232
Cdd:COG1121 21 VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAIL----GLLPPTSGTVRLFGKPP----RRARRRIGYvpqRAEVDWDFP- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 233 LTVGDTLEFAARLRTPQNRGLG-VDRETYAKHMASVymatyGILRQRNTPVGNefvpgCSGGERKRVSIAEVSLSGANIQ 311
Cdd:COG1121 92 ITVRDVVLMGRYGRRGLFRRPSrADREAVDEALERV-----GLEDLADRPIGE-----LSGGQQQRVLLARALAQDPDLL 161
|
170 180
....*....|....*....|..
gi 344304674 312 CWDNATRGLDAATALEFIRALK 333
Cdd:COG1121 162 LLDEPFAGVDAATEEALYELLR 183
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
863-1064 |
1.04e-09 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 60.92 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCL-------SDRHTVGVIT-DGVKMVNGH-SLDSSFQRSIGYVQQQDLHL 933
Cdd:PRK11264 18 VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCInlleqpeAGTIRVGDITiDTARSLSQQkGLIRQLRQHVGFVFQNFNLF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKfsaylrQSNTTPDKE-KDAYVDYIIDLLemseyadAMVGVAGSG------LNIEQRKRLTIGVELVAKPK 1006
Cdd:PRK11264 98 PHRTVLENII------EGPVIVKGEpKEEATARARELL-------AKVGLAGKEtsyprrLSGGQQQRVAIARALAMRPE 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1007 LLLFlDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSalllteF-----DRLLFLQEG 1064
Cdd:PRK11264 165 VILF-DEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMS------FardvaDRAIFMDQG 220
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
164-339 |
1.13e-09 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 60.21 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLA---VNTYGfqvdkDSKVS-YDGLTPDeieKHYRGDVIYSAETDEHFPQLTVGDTL 239
Cdd:cd03263 25 VYKGEIFGLLGHNGAGKTTTLKMLTgelRPTSG-----TAYINgYSIRTDR---KAARQSLGYCPQFDALFDELTVREHL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 240 EFAARLRtpqnrGLgvdRETYAKHMASVYMATYGILRQRNTPVGNefvpgCSGGERKRVSIAEVSLSGANIQCWDNATRG 319
Cdd:cd03263 97 RFYARLK-----GL---PKSEIKEEVELLLRVLGLTDKANKRART-----LSGGMKRKLSLAIALIGGPSVLLLDEPTSG 163
|
170 180
....*....|....*....|...
gi 344304674 320 LDAAT---ALEFIRALKTSSAVL 339
Cdd:cd03263 164 LDPASrraIWDLILEVRKGRSII 186
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
871-1045 |
1.43e-09 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 60.24 E-value: 1.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT-DGVKMVNGHSLDS------SFQRsiGYVQQQDLHLQtstvreALK 943
Cdd:COG4138 19 VNAGELIHLIGPNGAGKSTLLARMA-----GLLPgQGEILLNGRPLSDwsaaelARHR--AYLSQQQSPPF------AMP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 944 FSAYLR--QSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlniE-QRKRLTiGVELVAKPKL-----LLFLDEPT 1015
Cdd:COG4138 86 VFQYLAlhQPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGG---EwQRVRLA-AVLLQVWPTInpegqLLLLDEPM 161
|
170 180 190
....*....|....*....|....*....|..
gi 344304674 1016 SGLD--SQTAwsICKLMRKLADHGQAILCTIH 1045
Cdd:COG4138 162 NSLDvaQQAA--LDRLLRELCQQGITVVMSSH 191
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
875-1064 |
1.58e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 63.11 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 875 EITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSSF---QRSIGYVQQQDLHLQTSTVREALKFSAYLR 949
Cdd:TIGR01257 957 QITAFLGHNGAGKTTTLSILT-----GLLppTSGTVLVGGKDIETNLdavRQSLGMCPQHNILFHHLTVAEHILFYAQLK 1031
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 950 -QSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGvagsGLnieQRKrLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICK 1028
Cdd:TIGR01257 1032 gRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSG----GM---QRK-LSVAIAFVGDAKVVV-LDEPTSGVDPYSRRSIWD 1102
|
170 180 190
....*....|....*....|....*....|....*.
gi 344304674 1029 LMRKLADHGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:TIGR01257 1103 LLLKYRSGRTIIMSTHHMDEADLLG--DRIAIISQG 1136
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
860-1045 |
1.71e-09 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 60.10 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS-----DRHTVGVitDGVKMVNGHSLDSSFQRSIgyvQQQDLHLQ 934
Cdd:COG4604 13 GKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISrllppDSGEVLV--DGLDVATTPSRELAKRLAI---LRQENHIN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TS-TVREALKFSAYlRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMV-----GvagsglnieQRKRLTIGVELVAKPKLL 1008
Cdd:COG4604 88 SRlTVRELVAFGRF-PYSKGRLTAEDREIIDEAIAYLDLEDLADRYLdelsgG---------QRQRAFIAMVLAQDTDYV 157
|
170 180 190
....*....|....*....|....*....|....*...
gi 344304674 1009 LfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIH 1045
Cdd:COG4604 158 L-LDEPLNNLDMKHSVQMMKLLRRLADeLGKTVVIVLH 194
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
873-1064 |
1.85e-09 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 60.17 E-value: 1.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 873 PGEITALMGATGAGKTTLLNCLSDRHTVG--VITDGVKMVNGHSLDS------SFQRSIGYVQQQDlhlqtstvrEALKF 944
Cdd:PRK14239 30 PNEITALIGPSGSGKSTLLRSINRMNDLNpeVTITGSIVYNGHNIYSprtdtvDLRKEIGMVFQQP---------NPFPM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 945 SAY------LRqSNTTPDKEK-DAYV----------DYIIDLLEmseyaDAMVGVAGSglnieQRKRLTIGVELVAKPKL 1007
Cdd:PRK14239 101 SIYenvvygLR-LKGIKDKQVlDEAVekslkgasiwDEVKDRLH-----DSALGLSGG-----QQQRVCIARVLATSPKI 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 1008 LLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCT--IHQPSALLltefDRLLFLQEG 1064
Cdd:PRK14239 170 IL-LDEPTSALDPISAGKIEETLLGLKDDYTMLLVTrsMQQASRIS----DRTGFFLDG 223
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
861-1033 |
2.60e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 59.71 E-value: 2.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 861 RIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLD--SSFQRS--IGYVqQQDLHLQ 934
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIA-----GSLppDSGSILIDGKDVTklPEYKRAkyIGRV-FQDPMMG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TS---TVRE--ALkfsAYLR-QSNT----TPDKEKDAYVDYIIDL-LEMSEYADAMVGVAGSGlnieQRKRLTIGVELVA 1003
Cdd:COG1101 93 TApsmTIEEnlAL---AYRRgKRRGlrrgLTKKRRELFRELLATLgLGLENRLDTKVGLLSGG----QRQALSLLMATLT 165
|
170 180 190
....*....|....*....|....*....|
gi 344304674 1004 KPKLLLfLDEPTSGLDSQTAWSICKLMRKL 1033
Cdd:COG1101 166 KPKLLL-LDEHTAALDPKTAALVLELTEKI 194
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
164-324 |
3.18e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 58.35 E-value: 3.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGltPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLEFAA 243
Cdd:PRK13539 25 LAAGEALVLTGPNGSGKTTLLRLIA----GLLPPAAGTIKLDG--GDIDDPDVAEACHYLGHRNAMKPALTVAENLEFWA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 244 RLRTpqNRGLGVDRETYAkhmasvyMATYGILrqrNTPVGNefvpgCSGGERKRVSIAEVSLSGANIQCWDNATRGLDAA 323
Cdd:PRK13539 99 AFLG--GEELDIAAALEA-------VGLAPLA---HLPFGY-----LSAGQKRRVALARLLVSNRPIWILDEPTAALDAA 161
|
.
gi 344304674 324 T 324
Cdd:PRK13539 162 A 162
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
854-1064 |
3.19e-09 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 59.64 E-value: 3.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRII-----LDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVITdGVKMVNGHS--LDSSFQRS---- 922
Cdd:PRK09984 5 IRVEKLAKTFnqhqaLHAVDLNIHHGEMVALLGPSGSGKSTLL-----RHLSGLIT-GDKSAGSHIelLGRTVQREgrla 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 ---------IGYVQQQDLHLQTSTVRE-----ALKFSAYLRQ--SNTTPDKEKDAYvdYIIDLLEMSEYADAMVGVAGSG 986
Cdd:PRK09984 79 rdirksranTGYIFQQFNLVNRLSVLEnvligALGSTPFWRTcfSWFTREQKQRAL--QALTRVGMVHFAHQRVSTLSGG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 987 lnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPS-ALLLTEfdRLLFLQEG 1064
Cdd:PRK09984 157 ----QQQRVAIARALMQQAKVIL-ADEPIASLDPESARIVMDTLRDInQNDGITVVVTLHQVDyALRYCE--RIVALRQG 229
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
851-1124 |
3.67e-09 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 59.64 E-value: 3.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 851 TYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDSSfQRSIGYVQQ 928
Cdd:PRK13638 4 TSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLS-----GLLrpQKGAVLWQGKPLDYS-KRGLLALRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 929 Q--------DLHLQTSTVREALKFSayLRQSNTtPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVE 1000
Cdd:PRK13638 78 QvatvfqdpEQQIFYTDIDSDIAFS--LRNLGV-PEAEITRRVDEALTLVDAQHFRHQPIQCLSHG----QKKRVAIAGA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 1001 LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSalLLTEFDRLLFLQEGGQTVYFGDLGE--NCQ 1078
Cdd:PRK13638 151 LVLQARYLL-LDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDID--LIYEISDAVYVLRQGQILTHGAPGEvfACT 227
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 344304674 1079 TLInyfEKYGAdacpkdANPaeWMLKVVG--AAPGSHAEADYFQVWRK 1124
Cdd:PRK13638 228 EAM---EQAGL------TQP--WLVKLHTqlGLPLCKTETEFFHRMQK 264
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
873-1064 |
5.36e-09 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 58.78 E-value: 5.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 873 PGEITALMGATGAGKTTLLNCLS-----DRHTVGVITDGVKMVNGHSLDSSFQRSI-----GYVQQ---QDLHLQTS--- 936
Cdd:PRK11701 31 PGEVLGIVGESGSGKTTLLNALSarlapDAGEVHYRMRDGQLRDLYALSEAERRRLlrtewGFVHQhprDGLRMQVSagg 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREAL-----KFSAYLRQSNTT--PDKEKDAyvDYIIDLleMSEYADAMvgvagsglnieqRKRLTIGVELVAKPKLLl 1009
Cdd:PRK11701 111 NIGERLmavgaRHYGDIRATAGDwlERVEIDA--ARIDDL--PTTFSGGM------------QQRLQIARNLVTHPRLV- 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 1010 FLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPS-ALLLTefDRLLFLQEG 1064
Cdd:PRK11701 174 FMDEPTGGLDVSVQARLLDLLRGLvRELGLAVVIVTHDLAvARLLA--HRLLVMKQG 228
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
872-1064 |
6.47e-09 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 58.44 E-value: 6.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 872 KPGEITALMGATGAGKTTLLNCLS--DRHTVGVI------------TDG-VKMVNGHSLDSSFQRSIGYVQQQDLHLQTS 936
Cdd:PRK10619 29 NAGDVISIIGSSGSGKSTFLRCINflEKPSEGSIvvngqtinlvrdKDGqLKVADKNQLRLLRTRLTMVFQHFNLWSHMT 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKfsAYLRQSNTTPDKEKDAYVDYIiDLLEMSEYADAMVGVAGSGlniEQRKRLTIGVELVAKPKLLLFlDEPTS 1016
Cdd:PRK10619 109 VLENVME--APIQVLGLSKQEARERAVKYL-AKVGIDERAQGKYPVHLSG---GQQQRVSIARALAMEPEVLLF-DEPTS 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1017 GLDSQTAWSICKLMRKLADHGQAILCTIHQpsalllTEFDR-----LLFLQEG 1064
Cdd:PRK10619 182 ALDPELVGEVLRIMQQLAEEGKTMVVVTHE------MGFARhvsshVIFLHQG 228
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
864-1064 |
1.14e-08 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 57.58 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLN--CLSDRHTVGVITDGVKMVNGHSLDSSFQRSIGYVQQQDLHLQTSTVREA 941
Cdd:PRK11614 21 LHEVSLHINQGEIVTLIGANGAGKTTLLGtlCGDPRATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEEN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 942 LKFSAYLrqsnttpdKEKDAYVDYIIDLLEM-SEYADAMVGVAGSGLNIEQrKRLTIGVELVAKPKLLLfLDEPTSGLDS 1020
Cdd:PRK11614 101 LAMGGFF--------AERDQFQERIKWVYELfPRLHERRIQRAGTMSGGEQ-QMLAIGRALMSQPRLLL-LDEPSLGLAP 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 344304674 1021 QTAWSICKLMRKLADHGQAILcTIHQPSALLLTEFDRLLFLQEG 1064
Cdd:PRK11614 171 IIIQQIFDTIEQLREQGMTIF-LVEQNANQALKLADRGYVLENG 213
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
164-301 |
1.41e-08 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 56.76 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG-----LTPdeiekhYRGDVIYSAETDEHFPQLTVGDT 238
Cdd:cd03259 23 VEPGEFLALLGPSGCGKTTLLRLIA----GLERPDSGEILIDGrdvtgVPP------ERRNIGMVFQDYALFPHLTVAEN 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 344304674 239 LEFAARLRtpqnrglGVDRETYAKHMASVymatygILRQRNTPVGNEFVPGCSGGERKRVSIA 301
Cdd:cd03259 93 IAFGLKLR-------GVPKAEIRARVREL------LELVGLEGLLNRYPHELSGGQQQRVALA 142
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
861-1067 |
1.41e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 57.80 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 861 RIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--------RHTVGVITDGVKMVNGHSLdSSFQRSIGYVQQQDLH 932
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRmndkvsgyRYSGDVLLGGRSIFNYRDV-LEFRRRVGMLFQRPNP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 933 LQTSTVREALkfsAYLRQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLD 1012
Cdd:PRK14271 113 FPMSIMDNVL---AGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLL-LD 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1013 EPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSALLLTEFDRLLF---LQEGGQT 1067
Cdd:PRK14271 189 EPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFdgrLVEEGPT 246
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
854-1064 |
1.61e-08 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 57.53 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGHSLDSSFQRSIGYVQQQDLH- 932
Cdd:PRK13547 7 LHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAPRGARVTGDVTLNGEPLAAIDAPRLARLRa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 933 LQTSTVREALKFSA----------YLRQSNTTPDKEKDayvdyIID-LLEMSEyADAMVG-----VAGSGLNIEQRKRLT 996
Cdd:PRK13547 87 VLPQAAQPAFAFSAreivllgrypHARRAGALTHRDGE-----IAWqALALAG-ATALVGrdvttLSGGELARVQFARVL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 997 IGV---ELVAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPSaLLLTEFDRLLFLQEG 1064
Cdd:PRK13547 161 AQLwppHDAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLArDWNLGVLAIVHDPN-LAARHADRIAMLADG 231
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
848-1064 |
2.16e-08 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 55.40 E-value: 2.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIriKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL----SDRHtvGVIT-DGvkmVNGHSLDSSFQRS 922
Cdd:cd03247 4 NNVSFSY--PEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLtgdlKPQQ--GEITlDG---VPVSDLEKALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 IGYVQQQdLHLqtstvrealkFSAYLRQSnttpdkekdayvdyiidllemseyadamVGVAGSGlniEQRKRLTIGVELV 1002
Cdd:cd03247 77 ISVLNQR-PYL----------FDTTLRNN----------------------------LGRRFSG---GERQRLALARILL 114
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1003 AKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADhGQAILCTIHQPSAllLTEFDRLLFLQEG 1064
Cdd:cd03247 115 QDAPIVL-LDEPTVGLDPITERQLLSLIFEVLK-DKTLIWITHHLTG--IEHMDKILFLENG 172
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
860-1047 |
2.29e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 56.04 E-value: 2.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDG-VKMVNGHSLDSSFQRSIGYVQQQDLHLQTS 936
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLL-----RLIAGLLppAAGtIKLDGGDIDDPDVAEACHYLGHRNAMKPAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKF-SAYLRQSNTTPDkekDAyvdyiIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPT 1015
Cdd:PRK13539 89 TVAENLEFwAAFLGGEELDIA---AA-----LEAVGLAPLAHLPFGYLSAG----QKRRVALARLLVSNRPIWI-LDEPT 155
|
170 180 190
....*....|....*....|....*....|...
gi 344304674 1016 SGLDSQTAWSICKLMR-KLADHGQAILCTiHQP 1047
Cdd:PRK13539 156 AALDAAAVALFAELIRaHLAQGGIVIAAT-HIP 187
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
859-1022 |
2.67e-08 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 58.15 E-value: 2.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGVIT-DGVKMVNGHSLdssfqrSIGYV-QQQD-LHLqT 935
Cdd:COG0488 326 GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLL-----AGELEpDSGTVKLGETV------KIGYFdQHQEeLDP-D 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREalkfsaYLRQSNttpDKEKDAYVdyiIDLLEM----SEYADAMVGVAgSGlniEQRKRLTIGVELVAKPKLLLfL 1011
Cdd:COG0488 394 KTVLD------ELRDGA---PGGTEQEV---RGYLGRflfsGDDAFKPVGVL-SG---GEKARLALAKLLLSPPNVLL-L 456
|
170
....*....|.
gi 344304674 1012 DEPTSGLDSQT 1022
Cdd:COG0488 457 DEPTNHLDIET 467
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
872-1037 |
2.99e-08 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 56.18 E-value: 2.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 872 KPGEITALMGATGAGKTTLLNCLSdrhTVGVITDGVKMVNGHSLDSS----------FQRSIGYV-QQQDL--HLqtsTV 938
Cdd:PRK11124 26 PQGETLVLLGPSGAGKSSLLRVLN---LLEMPRSGTLNIAGNHFDFSktpsdkaireLRRNVGMVfQQYNLwpHL---TV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 939 REALkFSAYLRQSNTTPDKEKdAYVDYIIDLLEMSEYADAM-VGVAGSglnieQRKRLTIGVELVAKPKLLLFlDEPTSG 1017
Cdd:PRK11124 100 QQNL-IEAPCRVLGLSKDQAL-ARAEKLLERLRLKPYADRFpLHLSGG-----QQQRVAIARALMMEPQVLLF-DEPTAA 171
|
170 180
....*....|....*....|
gi 344304674 1018 LDSQTAWSICKLMRKLADHG 1037
Cdd:PRK11124 172 LDPEITAQIVSIIRELAETG 191
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
848-1075 |
4.23e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 56.35 E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYeirIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLnclsdRHTVGVI--TDGVKMVNGHSLDSS----FQR 921
Cdd:PRK13652 7 RDLCY---SYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLF-----RHFNGILkpTSGSVLIRGEPITKEnireVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYV-QQQDLHLQTSTVREALKFSAylrqSNTTPDKEKDAY-VDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGV 999
Cdd:PRK13652 79 FVGLVfQNPDDQIFSPTVEQDIAFGP----INLGLDEETVAHrVSSALHMLGLEELRDRVPHHLSGG----EKKRVAIAG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 1000 ELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPSalLLTEFDRLLFLQEGGQTVYFGDLGE 1075
Cdd:PRK13652 151 VIAMEPQVLV-LDEPTAGLDPQGVKELIDFLNDLPEtYGMTVIFSTHQLD--LVPEMADYIYVMDKGRIVAYGTVEE 224
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
849-1071 |
4.57e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 56.28 E-value: 4.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 849 DLTYEIRIKKEDRIILDhVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVITDGVKMVNGHSLDSSFQ---RSI 923
Cdd:PRK13643 8 NYTYQPNSPFASRALFD-IDLEVKKGSYTALIGHTGSGKSTLLQHLNGllQPTEGKVTVGDIVVSSTSKQKEIKpvrKKV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 924 GYVQQ-QDLHLQTSTVreaLKFSAYLRQSNTTPDKEKDAYVDYIIDLLEMSE--YADAMVGVAGSglnieQRKRLTIGVE 1000
Cdd:PRK13643 87 GVVFQfPESQLFEETV---LKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADefWEKSPFELSGG-----QMRRVAIAGI 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 1001 LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAllLTEFDRLLFLQEGGQTVYFG 1071
Cdd:PRK13643 159 LAMEPEVLV-LDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDD--VADYADYVYLLEKGHIISCG 226
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
863-1045 |
4.79e-08 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 55.59 E-value: 4.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLD--SSF------QRSIGYVQQQDLHLQ 934
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTP---TSGDVIFNGQPMSklSSAakaelrNQKLGFIYQFHHLLP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 TSTVREALKFSAYLRQSNTTPDKEKdayvdyiidLLEMSeyadAMVGVAG------SGLNIEQRKRLTIGVELVAKPKLL 1008
Cdd:PRK11629 101 DFTALENVAMPLLIGKKKPAEINSR---------ALEML----AAVGLEHranhrpSELSGGERQRVAIARALVNNPRLV 167
|
170 180 190
....*....|....*....|....*....|....*...
gi 344304674 1009 LfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIH 1045
Cdd:PRK11629 168 L-ADEPTGNLDARNADSIFQLLGELnRLQGTAFLVVTH 204
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
871-1075 |
4.97e-08 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 55.53 E-value: 4.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSLDSS--FQRSIGYV-QQQDL--HLqtsTVRE--A 941
Cdd:COG3840 22 IAAGERVAILGPSGAGKSTLLNLIA-----GFLPpdSGRILWNGQDLTALppAERPVSMLfQENNLfpHL---TVAQniG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 942 LKFSAYLRQsnTTPDKEKdayvdyIIDLLEmseyadaMVGVAG---------SGlniEQRKRLTIGVELVAKPKLLLfLD 1012
Cdd:COG3840 94 LGLRPGLKL--TAEQRAQ------VEQALE-------RVGLAGlldrlpgqlSG---GQRQRVALARCLVRKRPILL-LD 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 1013 EPTSGLDSQTAWSICKLMRKLAD-HGQAILCTIHQPS-ALLLTefDRLLFLqEGGQTVYFGDLGE 1075
Cdd:COG3840 155 EPFSALDPALRQEMLDLVDELCReRGLTVLMVTHDPEdAARIA--DRVLLV-ADGRIAADGPTAA 216
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
154-375 |
5.18e-08 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 57.22 E-value: 5.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 154 FDILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvNTYGFQVDKDSKVSYDGLTPDEIEKHYRGDVI--YSAETDEHFP 231
Cdd:COG1123 19 VPAVDGVSLTIAPGETVALVGESGSGKSTLALALM-GLLPHGGRISGEVLLDGRDLLELSEALRGRRIgmVFQDPMTQLN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 232 QLTVGDTLEFAARLRtpqnrglGVDRETyAKHMASVYMATYGILRQRNTPVgNEFvpgcSGGERKRVSIAEVSLSGANIQ 311
Cdd:COG1123 98 PVTVGDQIAEALENL-------GLSRAE-ARARVLELLEAVGLERRLDRYP-HQL----SGGQRQRVAIAMALALDPDLL 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344304674 312 CWDNATRGLDAATALEFIRALKTSSAVLDVTpVIAIYQCSQDAYDLFDNVSVLYGGHQIFFGKA 375
Cdd:COG1123 165 IADEPTTALDVTTQAEILDLLRELQRERGTT-VLLITHDLGVVAEIADRVVVMDDGRIVEDGPP 227
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
871-1055 |
6.35e-08 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 55.66 E-value: 6.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLSD--RHTVGVITdgvkmVNGHSLDSSFQRS-IGYVQQQDlHLQTS---TVREALKF 944
Cdd:PRK15056 30 VPGGSIAALVGVNGSGKSTLFKALMGfvRLASGKIS-----ILGQPTRQALQKNlVAYVPQSE-EVDWSfpvLVEDVVMM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 945 SAY-----LRQsnttPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGvELVAKPKLLLFLDEPTSGLD 1019
Cdd:PRK15056 104 GRYghmgwLRR----AKKRDRQIVTAALARVDMVEFRHRQIGELSGG----QKKRVFLA-RAIAQQGQVILLDEPFTGVD 174
|
170 180 190
....*....|....*....|....*....|....*.
gi 344304674 1020 SQTAWSICKLMRKLADHGQAILCTIHQPSAllLTEF 1055
Cdd:PRK15056 175 VKTEARIISLLRELRDEGKTMLVSTHNLGS--VTEF 208
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
864-1033 |
6.72e-08 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 57.34 E-value: 6.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTvgvITDGVKMVNGHSLD----SSFQRSIGYVQQQdLHLQTSTVR 939
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYD---IDEGEILLDGHDLRdytlASLRNQVALVSQN-VHLFNDTIA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALkfsAYLRQSN-TTPDKEKDAYVDYIIDLLE-MSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:PRK11176 435 NNI---AYARTEQySREQIEEAARMAYAMDFINkMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILI-LDEATSA 510
|
170
....*....|....*.
gi 344304674 1018 LDSQTAWSICKLMRKL 1033
Cdd:PRK11176 511 LDTESERAIQAALDEL 526
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
156-333 |
1.09e-07 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 54.08 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGfQVDKDS-KVSYDGLtPDEIEKHYRGDVIYSAETDEHFPqLT 234
Cdd:cd03235 14 VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAIL----G-LLKPTSgSIRVFGK-PLEKERKRIGYVPQRRSIDRDFP-IS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 235 VgdtLEFAARLRTPQNRGLG-VDRETYAKHMASvyMATYGILRQRNTPVGNefvpgCSGGERKRVSIAEVSLSGANIQCW 313
Cdd:cd03235 87 V---RDVVLMGLYGHKGLFRrLSKADKAKVDEA--LERVGLSELADRQIGE-----LSGGQQQRVLLARALVQDPDLLLL 156
|
170 180
....*....|....*....|
gi 344304674 314 DNATRGLDAATALEFIRALK 333
Cdd:cd03235 157 DEPFAGVDPKTQEDIYELLR 176
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
846-1075 |
1.14e-07 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 54.70 E-value: 1.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 846 LWRDLTYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGH-----SLDSS 918
Cdd:COG1134 24 LKELLLRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIA-----GILepTSGRVEVNGRvsallELGAG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 919 FqrsigyvqQQDLhlqtsTVREALKFSA-YLRQSNttpdKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTI 997
Cdd:COG1134 99 F--------HPEL-----TGRENIYLNGrLLGLSR----KEIDEKFDEIVEFAELGDFIDQPVKTYSSG----MRARLAF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLD------SQtawsicKLMRKLADHGQAILCTIHQPSAllLTEF-DRLLFLqEGGQTVYF 1070
Cdd:COG1134 158 AVATAVDPDILL-VDEVLAVGDaafqkkCL------ARIRELRESGRTVIFVSHSMGA--VRRLcDRAIWL-EKGRLVMD 227
|
....*
gi 344304674 1071 GDLGE 1075
Cdd:COG1134 228 GDPEE 232
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
864-1045 |
1.25e-07 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 56.07 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVIT-DGVKMVNGHSLDsSFQRSIGyVQQQDLHLQTS-TVR 939
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYqpDAGSILiDGQEMRFASTTA-ALAAGVA-IIYQELHLVPEmTVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALkfsaYLRQsntTPDKEKdayvdyIIDLLEMseYADAMVGVAGSGLNIE---QRKRLTIG----VElVAKPKLL---- 1008
Cdd:PRK11288 98 ENL----YLGQ---LPHKGG------IVNRRLL--NYEAREQLEHLGVDIDpdtPLKYLSIGqrqmVE-IAKALARnarv 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 344304674 1009 LFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 1045
Cdd:PRK11288 162 IAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSH 198
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
864-1046 |
1.79e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 55.51 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCL---SDRHTVGVITDGvKMVNGHSLDSSFQRSIGYVQQQ-DLHLQTStVR 939
Cdd:PRK10982 14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLfgiYQKDSGSILFQG-KEIDFKSSKEALENGISMVHQElNLVLQRS-VM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFSAYlrqsnttPDK-----EKDAYVDYIIDLLEMSEYADAMVGVAgsGLNIEQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:PRK10982 92 DNMWLGRY-------PTKgmfvdQDKMYRDTKAIFDELDIDIDPRAKVA--TLSVSQMQMIEIAKAFSYNAKIVI-MDEP 161
|
170 180 190
....*....|....*....|....*....|..
gi 344304674 1015 TSGLDSQTAWSICKLMRKLADHGQAILCTIHQ 1046
Cdd:PRK10982 162 TSSLTEKEVNHLFTIIRKLKERGCGIVYISHK 193
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
864-1033 |
2.01e-07 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 53.84 E-value: 2.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNcLSDR---HTVGVITdgvkmVNGH---SLD-SSFQRSIGYVQQQDLHLQTS 936
Cdd:cd03295 17 VNNLNLEIAKGEFLVLIGPSGSGKTTTMK-MINRliePTSGEIF-----IDGEdirEQDpVELRRKIGYVIQQIGLFPHM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALkfsAYLRQSNTTPDKEKDAYVDYIIDL--LEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:cd03295 91 TVEENI---ALVPKLLKWPKEKIRERADELLALvgLDPAEFADRYPHELSGG----QQQRVGVARALAADPPLLL-MDEP 162
|
170
....*....|....*....
gi 344304674 1015 TSGLDSQTAWSICKLMRKL 1033
Cdd:cd03295 163 FGALDPITRDQLQEEFKRL 181
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
164-385 |
2.07e-07 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 53.49 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIE-KHYRGDVIY---SAETdehfpQL---TVG 236
Cdd:COG1122 24 IEKGEFVAIIGPNGSGKSTLLRLLN----GLLKPTSGEVLVDGKDITKKNlRELRRKVGLvfqNPDD-----QLfapTVE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 237 DTLEFAarlrtPQNrgLGVDRETyAKHMASVYMATYGI--LRQRNTPVgnefvpgCSGGERKRVSIAEVS--------Ls 306
Cdd:COG1122 95 EDVAFG-----PEN--LGLPREE-IRERVEEALELVGLehLADRPPHE-------LSGGQKQRVAIAGVLamepevlvL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 307 ganiqcwDNATRGLDAATALEFIRALKTSSAvLDVTPVIAiyqcSQD---AYDLFDNVSVLYGGHQIFFGkanKAKEYFT 383
Cdd:COG1122 159 -------DEPTAGLDPRGRRELLELLKRLNK-EGKTVIIV----THDldlVAELADRVIVLDDGRIVADG---TPREVFS 223
|
..
gi 344304674 384 NM 385
Cdd:COG1122 224 DY 225
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
864-1072 |
2.23e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 54.32 E-value: 2.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTL---LNCL--------------------SDRHTVGVITDGVKMVNGHSLD--SS 918
Cdd:PRK13651 23 LDNVSVEINQGEFIAIIGQTGSGKTTFiehLNALllpdtgtiewifkdeknkkkTKEKEKVLEKLVIQKTRFKKIKkiKE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 919 FQRSIGYVQQ-QDLHLQTSTVREALKFSAylRQSNTTPDKEKDAYVDYI------IDLLEMSEYadamvgvagsGLNIEQ 991
Cdd:PRK13651 103 IRRRVGVVFQfAEYQLFEQTIEKDIIFGP--VSMGVSKEEAKKRAAKYIelvgldESYLQRSPF----------ELSGGQ 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 992 RKRLTIGVELVAKPKLLlFLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQ-PSALLLTEfdRLLFLQEgGQTVYF 1070
Cdd:PRK13651 171 KRRVALAGILAMEPDFL-VFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDlDNVLEWTK--RTIFFKD-GKIIKD 246
|
..
gi 344304674 1071 GD 1072
Cdd:PRK13651 247 GD 248
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
865-1019 |
2.57e-07 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 55.52 E-value: 2.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 865 DHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLDS---SFQRSIGYVQQ-----QDLhlq 934
Cdd:NF033858 283 DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLT-----GLLpaSEGEAWLFGQPVDAgdiATRRRVGYMSQafslyGEL--- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 tsTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAMvgvAGSgLNIEQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:NF033858 355 --TVRQNLELHARLFH---LPAAEIAARVAEMLERFDLADVADAL---PDS-LPLGIRQRLSLAVAVIHKPELLI-LDEP 424
|
....*
gi 344304674 1015 TSGLD 1019
Cdd:NF033858 425 TSGVD 429
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
860-1019 |
2.71e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 55.02 E-value: 2.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITD----GVKMVNGHSL-DssFQRSIGYVQQQdLHLQ 934
Cdd:PRK10938 272 DRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDltlfGRRRGSGETIwD--IKKHIGYVSSS-LHLD 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 935 ---TSTVREALkFSAY-----LRQsnTTPDKEKdAYVDYIIDLLEMSEY-ADAMVgvagSGLNIEQRKRLTIGVELVAKP 1005
Cdd:PRK10938 349 yrvSTSVRNVI-LSGFfdsigIYQ--AVSDRQQ-KLAQQWLDILGIDKRtADAPF----HSLSWGQQRLALIVRALVKHP 420
|
170
....*....|....
gi 344304674 1006 KLLLfLDEPTSGLD 1019
Cdd:PRK10938 421 TLLI-LDEPLQGLD 433
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
848-1047 |
2.73e-07 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 52.88 E-value: 2.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEirikKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNG---HSLDSSFQRS 922
Cdd:PRK13538 5 RNLACE----RDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILA-----GLArpDAGEVLWQGepiRRQRDEYHQD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 IGYVQQQ-----DLhlqtsTVREALKFSAYLRQSNTTpdkekdayvDYIIDLLE---MSEYADAMVGV--AGsglnieQR 992
Cdd:PRK13538 76 LLYLGHQpgiktEL-----TALENLRFYQRLHGPGDD---------EALWEALAqvgLAGFEDVPVRQlsAG------QQ 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 993 KRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQP 1047
Cdd:PRK13538 136 RRVALARLWLTRAPLWI-LDEPFTAIDKQGVARLEALLAQHAEQGGMVILTTHQD 189
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
871-1036 |
3.13e-07 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 53.50 E-value: 3.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCL---SDrHTVGVITDGVKMVNGHSLDSS--------------FQR------SI---- 923
Cdd:COG1117 34 IPENKVTALIGPSGCGKSTLLRCLnrmND-LIPGARVEGEILLDGEDIYDPdvdvvelrrrvgmvFQKpnpfpkSIydnv 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 924 -------GYVQQQDLHlqtSTVREALKfSAYLrqsnttPDKEKDAyvdyiidlLEMSeyadamvgvaGSGLNIEQRKRLT 996
Cdd:COG1117 113 ayglrlhGIKSKSELD---EIVEESLR-KAAL------WDEVKDR--------LKKS----------ALGLSGGQQQRLC 164
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 344304674 997 IGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADH 1036
Cdd:COG1117 165 IARALAVEPEVLL-MDEPTSALDPISTAKIEELILELKKD 203
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
860-1033 |
3.65e-07 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 54.27 E-value: 3.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNC---LSDrhtvgvITDGVKMVNGHSLDS--SFQRSIGYV-QQQDL-- 931
Cdd:PRK11000 15 DVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMiagLED------ITSGDLFIGEKRMNDvpPAERGVGMVfQSYALyp 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLqtsTVREALKFSAYLRQSNTTpdkEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfL 1011
Cdd:PRK11000 89 HL---SVAENMSFGLKLAGAKKE---EINQRVNQVAEVLQLAHLLDRKPKALSGG----QRQRVAIGRTLVAEPSVFL-L 157
|
170 180
....*....|....*....|....*.
gi 344304674 1012 DEPTSGLDS----QTAWSICKLMRKL 1033
Cdd:PRK11000 158 DEPLSNLDAalrvQMRIEISRLHKRL 183
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
860-1022 |
3.71e-07 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 54.83 E-value: 3.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdRH---TVGVIT-DG--VKMVNGHSLdssfQRSIGYVQQqDLHL 933
Cdd:COG5265 370 ERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLF-RFydvTSGRILiDGqdIRDVTQASL----RAAIGIVPQ-DTVL 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALkfsAYLRQSNTTPDKE---KDAYVDYIIDLLEmsEYADAMVGVAG---SGlniEQRKRLTIGVELVAKPKL 1007
Cdd:COG5265 444 FNDTIAYNI---AYGRPDASEEEVEaaaRAAQIHDFIESLP--DGYDTRVGERGlklSG---GEKQRVAIARTLLKNPPI 515
|
170
....*....|....*
gi 344304674 1008 LLFlDEPTSGLDSQT 1022
Cdd:COG5265 516 LIF-DEATSALDSRT 529
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
864-1041 |
4.85e-07 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 54.26 E-value: 4.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVI--TDGVKMVNGHSLD-SSFQRS----IGYVQQqdlHL--- 933
Cdd:COG3845 21 NDDVSLTVRPGEIHALLGENGAGKSTLMKILY-----GLYqpDSGEILIDGKPVRiRSPRDAialgIGMVHQ---HFmlv 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVRE----ALKFSAYLRQSnttpdkeKDAYVDYIIDLleMSEYadamvgvagsGLNIEQRKR---LTIG----VE-- 1000
Cdd:COG3845 93 PNLTVAEnivlGLEPTKGGRLD-------RKAARARIREL--SERY----------GLDVDPDAKvedLSVGeqqrVEil 153
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 344304674 1001 --LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAIL 1041
Cdd:COG3845 154 kaLYRGARILI-LDEPTAVLTPQEADELFEILRRLAAEGKSII 195
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
853-1050 |
5.03e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.87 E-value: 5.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSLD---SSFQRSIGYVQ 927
Cdd:PRK13540 6 ELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIA-----GLLNpeKGEILFERQSIKkdlCTYQKQLCFVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 928 QQDLHLQTSTVREALKFSAYLRQSNTTpdkekdayVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKL 1007
Cdd:PRK13540 81 HRSGINPYLTLRENCLYDIHFSPGAVG--------ITELCRLFSLEHLIDYPCGLLSSG----QKRQVALLRLWMSKAKL 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 344304674 1008 LLfLDEPTSGLDSQtawSICKLMRKLADH---GQAILCTIHQPSAL 1050
Cdd:PRK13540 149 WL-LDEPLVALDEL---SLLTIITKIQEHrakGGAVLLTSHQDLPL 190
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
164-368 |
5.69e-07 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 51.24 E-value: 5.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFqVDKDS-KVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLEFa 242
Cdd:cd03230 23 VEKGEIYGLLGPNGAGKTTLIKIIL----GL-LKPDSgEIKVLGKDIKKEPEEVKRRIGYLPEEPSLYENLTVRENLKL- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 243 arlrtpqnrglgvdretyakhmasvymatygilrqrntpvgnefvpgcSGGERKRVSIAEVSLSGANIQCWDNATRGLDA 322
Cdd:cd03230 97 ------------------------------------------------SGGMKQRLALAQALLHDPELLILDEPTSGLDP 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 323 ATALEFIRALKT----------SSAVLDvtpviaiyqcsqDAYDLFDNVSVLYGGH 368
Cdd:cd03230 129 ESRREFWELLRElkkegktillSSHILE------------EAERLCDRVAILNNGR 172
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
876-1019 |
7.14e-07 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 53.34 E-value: 7.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 876 ITALMGATGAGKTTLLNCLS--DRHTVGVITdgvkmVNGHSL-DSS-------FQRSIGYVQQqdlhlqtstvrEALKFS 945
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISglTRPQKGRIV-----LNGRVLfDAEkgiclppEKRRIGYVFQ-----------DARLFP 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 946 AYLRQSNTT--PDKEKDAYVDYIIDLLEMseyaDAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:PRK11144 90 HYKVRGNLRygMAKSMVAQFDKIVALLGI----EPLLDRYPGSLSGGEKQRVAIGRALLTAPELLL-MDEPLASLD 160
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
823-1041 |
8.58e-07 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 53.48 E-value: 8.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 823 SDFEKKEIVELsengLTGenetflwRDLT--YEIRIKKEDRIILDhVDGW------------VKPGEITALMGATGAGKT 888
Cdd:COG1129 225 AELTEDELVRL----MVG-------RELEdlFPKRAAAPGEVVLE-VEGLsvggvvrdvsfsVRAGEILGIAGLVGAGRT 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 889 TLLNCL--SDRHTVGVIT-DGvKMVNGHSLDSSFQRSIGYV----QQQDLHLQTStVREALKFSAYLRQSN---TTPDKE 958
Cdd:COG1129 293 ELARALfgADPADSGEIRlDG-KPVRIRSPRDAIRAGIAYVpedrKGEGLVLDLS-IRENITLASLDRLSRgglLDRRRE 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 959 KDAYVDYIiDLLEMSeYADAMVGVAG-SGLNieQRKRLtIGVELVAKPKLLLfLDEPTSGLD----SQtawsICKLMRKL 1033
Cdd:COG1129 371 RALAEEYI-KRLRIK-TPSPEQPVGNlSGGN--QQKVV-LAKWLATDPKVLI-LDEPTRGIDvgakAE----IYRLIREL 440
|
....*...
gi 344304674 1034 ADHGQAIL 1041
Cdd:COG1129 441 AAEGKAVI 448
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
859-1064 |
8.75e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 51.97 E-value: 8.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTL---LNCLSDRHTVGVITDGVKMVNGHS---LDS-SFQRSIGYVQQQDL 931
Cdd:PRK14246 21 NDKAILKDITIKIPNNSIFGIMGPSGSGKSTLlkvLNRLIEIYDSKIKVDGKVLYFGKDifqIDAiKLRKEVGMVFQQPN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLQTSTVREALkfsAYLRQSNTTPDK-EKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLf 1010
Cdd:PRK14246 101 PFPHLSIYDNI---AYPLKSHGIKEKrEIKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLL- 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1011 LDEPTSGLDSQTAWSICKLMRKLADHgQAILCTIHQPSALLLTEfDRLLFLQEG 1064
Cdd:PRK14246 177 MDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVA-DYVAFLYNG 228
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
863-1064 |
9.39e-07 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 51.26 E-value: 9.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCL---SDRHTVGVITDGV--KMVNGHSLdssfQRSIGYVqQQDLHLQTST 937
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALfrfLEAEEGKIEIDGIdiSTIPLEDL----RSSLTII-PQDPTLFSGT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 938 VRealkfsaylrqSNTTPDKEKDAyvDYIIDLLEMSEyadamvgvAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSG 1017
Cdd:cd03369 98 IR-----------SNLDPFDEYSD--EEIYGALRVSE--------GGLNLSQGQRQLLCLARALLKRPRVLV-LDEATAS 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 344304674 1018 LDSQTAWSICKLMRKLADhGQAILCTIHQPSALLltEFDRLLFLQEG 1064
Cdd:cd03369 156 IDYATDALIQKTIREEFT-NSTILTIAHRLRTII--DYDKILVMDAG 199
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
834-1033 |
9.92e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 52.11 E-value: 9.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 834 SENGLTGENETFLWRDltyeirikkEDRIILDHVDGWVKPGEITALMGATGAGKTT---LLN--CLSDRHTVGVIT-DGV 907
Cdd:PRK13640 2 KDNIVEFKHVSFTYPD---------SKKPALNDISFSIPRGSWTALIGHNGSGKSTiskLINglLLPDDNPNSKITvDGI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 908 KMVNGHSLDssFQRSIGYV-QQQDLHLQTSTVREALKFSAYLRQsntTPDKEKDAYVDYIIDLLEMSEYADAmvgvAGSG 986
Cdd:PRK13640 73 TLTAKTVWD--IREKVGIVfQNPDNQFVGATVGDDVAFGLENRA---VPRPEMIKIVRDVLADVGMLDYIDS----EPAN 143
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 344304674 987 LNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 1033
Cdd:PRK13640 144 LSGGQKQRVAIAGILAVEPKIII-LDESTSMLDPAGKEQILKLIRKL 189
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
156-373 |
1.05e-06 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 51.04 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGeLTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTV 235
Cdd:cd03264 15 ALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILA----TLTPPSSGTIRIDGQDVLKQPQKLRRRIGYLPQEFGVYPNFTV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 GDTLEFAARLRtpqnrglGV-DREtyAKHMASVYMATYGILRQRNTPVGnefvpGCSGGERKRVSIAEVSLSGANIQCWD 314
Cdd:cd03264 90 REFLDYIAWLK-------GIpSKE--VKARVDEVLELVNLGDRAKKKIG-----SLSGGMRRRVGIAQALVGDPSILIVD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 344304674 315 NATRGLDAATALEFIRALKTSSAvlDVTPVIAIYQCSqDAYDLFDNVSVLYGGHQIFFG 373
Cdd:cd03264 156 EPTAGLDPEERIRFRNLLSELGE--DRIVILSTHIVE-DVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
146-373 |
1.08e-06 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 51.21 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 146 RKDDKSRYFDILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGL----TPDEIEK----HYR 217
Cdd:cd03266 10 RFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLA----GLLEPDAGFATVDGFdvvkEPAEARRrlgfVSD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 218 GDVIYsaetdehfPQLTVGDTLEFAARLRTPQNRGLGVDRETYAKHMAsvyMATYgilrqRNTPVGnefvpGCSGGERKR 297
Cdd:cd03266 86 STGLY--------DRLTARENLEYFAGLYGLKGDELTARLEELADRLG---MEEL-----LDRRVG-----GFSTGMRQK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 298 VSIAEVSLSGANIQCWDNATRGLD---AATALEFIRALKTS-SAVLDVTPVIaiyqcsQDAYDLFDNVSVLYGGHQIFFG 373
Cdd:cd03266 145 VAIARALVHDPPVLLLDEPTTGLDvmaTRALREFIRQLRALgKCILFSTHIM------QEVERLCDRVVVLHRGRVVYEG 218
|
|
| FlhF |
COG1419 |
Flagellar biosynthesis GTPase FlhF [Cell motility]; |
786-904 |
1.79e-06 |
|
Flagellar biosynthesis GTPase FlhF [Cell motility];
Pssm-ID: 441029 [Multi-domain] Cd Length: 361 Bit Score: 51.79 E-value: 1.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 786 LRSSLKQLKK--RKELAAQKQDIESASNEKVPLAEDLANSDFEKKEIVELSENGLTGENETFLWRDLTYEIRikkedRII 863
Cdd:COG1419 79 LRRELAELKEllEEQLSGLAGESARLPPELAELLERLLEAGVSPELARELLEKLPEDLSAEEAWRALLEALA-----RRL 153
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLL-----NC-LSDRHTVGVIT 904
Cdd:COG1419 154 PVAEDPLLDEGGVIALVGPTGVGKTTTIaklaaRFvLRGKKKVALIT 200
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
849-1044 |
1.82e-06 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 51.17 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 849 DLTYeiRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTL---LNCLSdRHTVGVITdgvkmVNGHSLDSS----FQR 921
Cdd:PRK13635 10 HISF--RYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLaklLNGLL-LPEAGTIT-----VGGMVLSEEtvwdVRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYV-QQQDLHLQTSTVREALKFSAylrQSNTTPDKEKDAYVDYIIDLLEMSEYADAmvgvAGSGLNIEQRKRLTIGVE 1000
Cdd:PRK13635 82 QVGMVfQNPDNQFVGATVQDDVAFGL---ENIGVPREEMVERVDQALRQVGMEDFLNR----EPHRLSGGQKQRVAIAGV 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 344304674 1001 LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTI 1044
Cdd:PRK13635 155 LALQPDIII-LDEATSMLDPRGRREVLETVRQLKEQKGITVLSI 197
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
144-321 |
1.88e-06 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 50.95 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 144 YFRKDDKSRYfdILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHY-RGDVIY 222
Cdd:cd03252 7 RFRYKPDGPV--ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQ----RFYVPENGRVLVDGHDLALADPAWlRRQVGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 223 SAETDEHFPQlTVGDTLEFAarlrtpqNRGLGVDRETYAKHMASVYMATYGILRQRNTPVGNEFVpGCSGGERKRVSIAE 302
Cdd:cd03252 81 VLQENVLFNR-SIRDNIALA-------DPGMSMERVIEAAKLAGAHDFISELPEGYDTIVGEQGA-GLSGGQRQRIAIAR 151
|
170
....*....|....*....
gi 344304674 303 VSLSGANIQCWDNATRGLD 321
Cdd:cd03252 152 ALIHNPRILIFDEATSALD 170
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
858-1064 |
3.25e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 50.37 E-value: 3.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 858 KEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVIT-DGVKmVNGHSLDsSFQRSIGYV-QQQDLHL 933
Cdd:PRK13632 19 NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGllKPQSGEIKiDGIT-ISKENLK-EIRKKIGIIfQNPDNQF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTVREALKFSayLRQSNTTPDKEKDayvdyIIDllemsEYADAmVGVAG------SGLNIEQRKRLTIGVELVAKPKL 1007
Cdd:PRK13632 97 IGATVEDDIAFG--LENKKVPPKKMKD-----IID-----DLAKK-VGMEDyldkepQNLSGGQKQRVAIASVLALNPEI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 344304674 1008 LLFlDEPTSGLDSQTAWSICKLMRKLADHGQAILCTI-HQPSALLLTefDRLLFLQEG 1064
Cdd:PRK13632 164 IIF-DESTSMLDPKGKREIKKIMVDLRKTRKKTLISItHDMDEAILA--DKVIVFSEG 218
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
871-1033 |
3.85e-06 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 50.85 E-value: 3.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLS--DRHTVGVITDGVKMVNG-HSLDssfqRSIGYVQQQDLHLQTSTVREALKFSAY 947
Cdd:PRK10851 25 IPSGQMVALLGPSGSGKTTLLRIIAglEHQTSGHIRFHGTDVSRlHARD----RKVGFVFQHYALFRHMTVFDNIAFGLT 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 948 LRQSNTTPDKEK-DAYVDYIIDLLEMSEYADAMvgvaGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSI 1026
Cdd:PRK10851 101 VLPRRERPNAAAiKAKVTQLLEMVQLAHLADRY----PAQLSGGQKQRVALARALAVEPQILL-LDEPFGALDAQVRKEL 175
|
....*..
gi 344304674 1027 CKLMRKL 1033
Cdd:PRK10851 176 RRWLRQL 182
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
759-1026 |
3.96e-06 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 51.87 E-value: 3.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 759 ALFFLVVYIMLTEFNKGAMKKGEITLFLRSSLkqlkkRKELAAQKQDIESASNEKVPLA--------EDLANSDFEKKEI 830
Cdd:TIGR00957 555 ALITFAVYVTVDENNILDAEKAFVSLALFNIL-----RFPLNILPMVISSIVQASVSLKrlriflshEELEPDSIERRTI 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 831 VELSENGLTGENETFLWrdltyeiriKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRhtvgvitdgVKMV 910
Cdd:TIGR00957 630 KPGEGNSITVHNATFTW---------ARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAE---------MDKV 691
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 911 NGHsldSSFQRSIGYVQQQDLhLQTSTVREALKFSAYLRQSNTTPDKEKDAyvdyIIDLLEMSEYADAM-VGVAGSGLNI 989
Cdd:TIGR00957 692 EGH---VHMKGSVAYVPQQAW-IQNDSLRENILFGKALNEKYYQQVLEACA----LLPDLEILPSGDRTeIGEKGVNLSG 763
|
250 260 270
....*....|....*....|....*....|....*..
gi 344304674 990 EQRKRLTIGVELVAKPKLLLFlDEPTSGLDSQTAWSI 1026
Cdd:TIGR00957 764 GQKQRVSLARAVYSNADIYLF-DDPLSAVDAHVGKHI 799
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
863-1045 |
4.47e-06 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 49.70 E-value: 4.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTV--GVITDGVKMVNGHSLDSsfqrsiGYVQQQDLHLQTSTVRE 940
Cdd:PRK11248 16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYqhGSITLDGKPVEGPGAER------GVVFQNEGLLPWRNVQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 941 ALKFSAYLRqsnTTPDKEKDAYVdyiidlLEMSeyadAMVGVAGSG------LNIEQRKRLTIGVELVAKPKLLLfLDEP 1014
Cdd:PRK11248 90 NVAFGLQLA---GVEKMQRLEIA------HQML----KKVGLEGAEkryiwqLSGGQRQRVGIARALAANPQLLL-LDEP 155
|
170 180 190
....*....|....*....|....*....|..
gi 344304674 1015 TSGLDSQTAWSICKLMRKL-ADHGQAILCTIH 1045
Cdd:PRK11248 156 FGALDAFTREQMQTLLLKLwQETGKQVLLITH 187
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
167-367 |
6.18e-06 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 49.03 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 167 GELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHYRgDVIYSAETDEHFPQLTVGDTLEFAarlR 246
Cdd:cd03298 24 GEITAIVGPSGSGKSTLLNLIA----GFETPQSGRVLINGVDVTAAPPADR-PVSMLFQENNLFAHLTVEQNVGLG---L 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 247 TPQNRGLGVDRETYAKHMASVYMAtyGILRQRntpvgnefvPG-CSGGERKRVSIAEVSLSGANIQCWDNATRGLDAATA 325
Cdd:cd03298 96 SPGLKLTAEDRQAIEVALARVGLA--GLEKRL---------PGeLSGGERQRVALARVLVRDKPVLLLDEPFAALDPALR 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 344304674 326 LEFIRALKTSSAVLDVTPVIAIYQcSQDAYDLFDNVSVLYGG 367
Cdd:cd03298 165 AEMLDLVLDLHAETKMTVLMVTHQ-PEDAKRLAQRVVFLDNG 205
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
853-1019 |
7.63e-06 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 49.95 E-value: 7.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 853 EIR-IKK--EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLD--SSFQRSIGYV- 926
Cdd:PRK09452 16 ELRgISKsfDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETP---DSGRIMLDGQDIThvPAENRHVNTVf 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 927 QQQDL--HLqtsTVREALKFSayLRQSNtTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAK 1004
Cdd:PRK09452 93 QSYALfpHM---TVFENVAFG--LRMQK-TPAAEITPRVMEALRMVQLEEFAQRKPHQLSGG----QQQRVAIARAVVNK 162
|
170
....*....|....*
gi 344304674 1005 PKLLLfLDEPTSGLD 1019
Cdd:PRK09452 163 PKVLL-LDESLSALD 176
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
151-301 |
7.97e-06 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 48.97 E-value: 7.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 151 SRYFDILKPMDGL---LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG-----LTPDEIEKhyRGdVIY 222
Cdd:cd03219 7 TKRFGGLVALDDVsfsVRPGEIHGLIGPNGAGKTTLFNLIS----GFLRPTSGSVLFDGeditgLPPHEIAR--LG-IGR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 223 SAETDEHFPQLTVGDTLEFAARLRTPQNRGLGVDRETYAKHMASV--YMATYGILRQRNTPVGNefvpgCSGGERKRVSI 300
Cdd:cd03219 80 TFQIPRLFPELTVLENVMVAAQARTGSGLLLARARREEREARERAeeLLERVGLADLADRPAGE-----LSYGQQRRLEI 154
|
.
gi 344304674 301 A 301
Cdd:cd03219 155 A 155
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
859-1045 |
8.39e-06 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 48.56 E-value: 8.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSD--RHTVGVItdgvkMVNGHslDSSFQRSIGYVQQQDLHLQT- 935
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASliSPTSGTL-----LFEGE--DISTLKPEIYRQQVSYCAQTp 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 ----STVREALKFSAYLRqsNTTPDKEKdayvdyIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfL 1011
Cdd:PRK10247 91 tlfgDTVYDNLIFPWQIR--NQQPDPAI------FLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLL-L 161
|
170 180 190
....*....|....*....|....*....|....*
gi 344304674 1012 DEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIH 1045
Cdd:PRK10247 162 DEITSALDESNKHNVNEIIHRYVrEQNIAVLWVTH 196
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
852-1019 |
8.65e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 49.32 E-value: 8.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 852 YEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTL---LNCLSdrhtvgVITDGVKMVNGhsLDSS-------FQR 921
Cdd:PRK13633 14 YESNEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIakhMNALL------IPSEGKVYVDG--LDTSdeenlwdIRN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 922 SIGYV-QQQDLHLQTSTVREALKFSAylrQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVE 1000
Cdd:PRK13633 86 KAGMVfQNPDNQIVATIVEEDVAFGP---ENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGG----QKQRVAIAGI 158
|
170
....*....|....*....
gi 344304674 1001 LVAKPKLLLFlDEPTSGLD 1019
Cdd:PRK13633 159 LAMRPECIIF-DEPTAMLD 176
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
156-368 |
9.18e-06 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 47.57 E-value: 9.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHY---RGDVIYSAETDEHFPQ 232
Cdd:cd03229 15 VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIA----GLEEPDSGSILIDGEDLTDLEDELpplRRRIGMVFQDFALFPH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 233 LTVGDtlefaarlrtpqNRGLGVdretyakhmasvymatygilrqrntpvgnefvpgcSGGERKRVSIAEVSLSGANIQC 312
Cdd:cd03229 91 LTVLE------------NIALGL-----------------------------------SGGQQQRVALARALAMDPDVLL 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 313 WDNATRGLDAATALEFIRALKTSSAVLDVTPVIAIYQCSqDAYDLFDNVSVLYGGH 368
Cdd:cd03229 124 LDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLD-EAARLADRVVVLRDGK 178
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
841-1072 |
1.92e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 48.19 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 841 ENETFLWRDLTYEirikkedriiLDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVgviTDGVKMVNGHSLDSSFQ 920
Cdd:PRK13647 8 EDLHFRYKDGTKA----------LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLP---QRGRVKVMGREVNAENE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 RSI----GYV-QQQDLHLQTSTVREALKFSAylRQSNTTPDkEKDAYVDYIIDLLEMSEYADAmvgvAGSGLNIEQRKRL 995
Cdd:PRK13647 75 KWVrskvGLVfQDPDDQVFSSTVWDDVAFGP--VNMGLDKD-EVERRVEEALKAVRMWDFRDK----PPYHLSYGQKKRV 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 996 TIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaLLLTEFDRLLFLQEgGQTVYFGD 1072
Cdd:PRK13647 148 AIAGVLAMDPDVIV-LDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVD-LAAEWADQVIVLKE-GRVLAEGD 221
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
525-688 |
1.95e-05 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 48.54 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 525 QTTNYMNY-RGIALFFGVLYNAFASLMEILSLFEARnIIE-------KHRKYALYRPSADAIASVIFelpikfmMSITFN 596
Cdd:pfam12698 155 PQSGYAYYlVGLILMIIILIGAAIIAVSIVEEKESR-IKErllvsgvSPLQYWLGKILGDFLVGLLQ-------LLIILL 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 597 LIFYFMINLRrEPGRFFYYWLMAIWCTLIMSHLfrcIGSLVTTVAQAMTPATVMLLAMVMYTGFVITTKEMLGWARWINY 676
Cdd:pfam12698 227 LLFGIGIPFG-NLGLLLLLFLLYGLAYIALGYL---LGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLEDPPSFLQWIFS 302
|
170
....*....|..
gi 344304674 677 INPVAYVFESFM 688
Cdd:pfam12698 303 IIPFFSPIDGLL 314
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
849-1062 |
2.35e-05 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 47.15 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 849 DLTYEirikKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGvitDGVKMVNGHSLDSSFQ-RSIGYVQ 927
Cdd:PRK13543 16 ALAFS----RNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVE---SGQIQIDGKTATRGDRsRFMAYLG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 928 -----QQDLhlqtSTVrEALKFSAYL--RQSNTTPDKEkdayvdyiIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGvE 1000
Cdd:PRK13543 89 hlpglKADL----STL-ENLHFLCGLhgRRAKQMPGSA--------LAIVGLAGYEDTLVRQLSAG----QKKRLALA-R 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 1001 LVAKPKLLLFLDEPTSGLDSQtawSICKLMRKLADH---GQAILCTIHQPSALLLTEfDRLLFLQ 1062
Cdd:PRK13543 151 LWLSPAPLWLLDEPYANLDLE---GITLVNRMISAHlrgGGAALVTTHGAYAAPPVR-TRMLTLE 211
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
851-1048 |
2.42e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 47.53 E-value: 2.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 851 TYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLL---NCLSDRHTVGVITDGVKM--VNGHSLDSS---FQRS 922
Cdd:PRK14267 7 TVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLrtfNRLLELNEEARVEGEVRLfgRNIYSPDVDpieVRRE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 923 IGYVQQQDLHLQTSTVRE----ALKFSAYLRqsnttPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIG 998
Cdd:PRK14267 87 VGMVFQYPNPFPHLTIYDnvaiGVKLNGLVK-----SKKELDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQRLVIA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 344304674 999 VELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTiHQPS 1048
Cdd:PRK14267 162 RALAMKPKILL-MDEPTANIDPVGTAKIEELLFELKKEYTIVLVT-HSPA 209
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
851-1068 |
3.84e-05 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 46.99 E-value: 3.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 851 TYEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLS--DRHTVGVIT---------DG---------VKMV 910
Cdd:PRK10419 15 HGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVglESPSQGNVSwrgeplaklNRaqrkafrrdIQMV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 911 nghsldssFQRSIGYVQQQdlhlqtSTVREALkfSAYLRQSNTTPDKEKDAYVDYIIDLLEMS-EYADAMVGVAGSGlni 989
Cdd:PRK10419 95 --------FQDSISAVNPR------KTVREII--REPLRHLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGG--- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 990 eQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSalLLTEFDRLLFLQEGGQTV 1068
Cdd:PRK10419 156 -QLQRVCLARALAVEPKLLI-LDEAVSNLDLVLQAGVIRLLKKLqQQFGTACLFITHDLR--LVERFCQRVMVMDNGQIV 231
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
854-928 |
4.37e-05 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 45.13 E-value: 4.37e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 344304674 854 IRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRH--TVGVITDGVKMvnghsldssfqrSIGYVQQ 928
Cdd:cd03221 6 LSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELepDEGIVTWGSTV------------KIGYFEQ 70
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
854-1019 |
4.71e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 46.71 E-value: 4.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGViTDGVKMVNGHSLDS-------------SFQ 920
Cdd:PRK09580 7 LHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEV-TGGTVEFKGKDLLElspedragegifmAFQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 R--SIGYVQQQdLHLQTS--TVREalkfsaYLRQsnttPDKEKDAYVDYI---IDLLEMSEyaDAMVGVAGSGLNIEQRK 993
Cdd:PRK09580 86 YpvEIPGVSNQ-FFLQTAlnAVRS------YRGQ----EPLDRFDFQDLMeekIALLKMPE--DLLTRSVNVGFSGGEKK 152
|
170 180
....*....|....*....|....*.
gi 344304674 994 RLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:PRK09580 153 RNDILQMAVLEPELCI-LDESDSGLD 177
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
873-1061 |
4.91e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.06 E-value: 4.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 873 PGEITALMGATGAGKTTLLNCL---SDRHTVGVItdgvkmvnghSLDSSFQRSIGYVQQQDlhlqtstvrealkfsaylr 949
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALareLGPPGGGVI----------YIDGEDILEEVLDQLLL------------------- 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 950 qsnttpdkekdayvdyiidllemseyadamVGVAGSGLNIEQRKRLTIGVELVAKPKL-LLFLDEPTSGLDSQTAWSI-- 1026
Cdd:smart00382 52 ------------------------------IIVGGKKASGSGELRLRLALALARKLKPdVLILDEITSLLDAEQEALLll 101
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 344304674 1027 ----CKLMRKLADHGQAILCTIHQP----SALLLTEFDRLLFL 1061
Cdd:smart00382 102 leelRLLLLLKSEKNLTVILTTNDEkdlgPALLRRRFDRRIVL 144
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
864-1046 |
4.98e-05 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 47.90 E-value: 4.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVG-----VITDGVKMVNGHSLDSSfQRSIGYVQQQDLHLQTSTV 938
Cdd:TIGR02633 17 LDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGtwdgeIYWSGSPLKASNIRDTE-RAGIVIIHQELTLVPELSV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 939 REALkfsaYLRQSNTTPDK--EKDAYVDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:TIGR02633 96 AENI----FLGNEITLPGGrmAYNAMYLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLLI-LDEPSS 170
|
170 180 190
....*....|....*....|....*....|
gi 344304674 1017 GLDSQTAWSICKLMRKLADHGQAILCTIHQ 1046
Cdd:TIGR02633 171 SLTEKETEILLDIIRDLKAHGVACVYISHK 200
|
|
| TagG |
COG1682 |
ABC-type polysaccharide/teichoic acid/polyol phosphate export permease [Carbohydrate transport ... |
510-687 |
5.08e-05 |
|
ABC-type polysaccharide/teichoic acid/polyol phosphate export permease [Carbohydrate transport and metabolism];
Pssm-ID: 441288 [Multi-domain] Cd Length: 258 Bit Score: 46.72 E-value: 5.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 510 GMMGLILSSIFYNLDQTTNYMNYrgiaLFFGVL-YNAFASLME--ILSLFEARNIIEKhrkyaLYRPSADA-IASVIFEL 585
Cdd:COG1682 44 LVYTFVFGVLLRAPSGGVPYALF----LLAGLLpWNFFSEALNrgSGSIVANAGLIKK-----VYFPREILpLARVLSAL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 586 pIKFMMSITfnLIFYFMINLRREPGR--------FFYYWLMAIWCTLIMSHL---FRCIGSLVTTVAQAMtpatvMLLAM 654
Cdd:COG1682 115 -VNFLISLV--VLLVVLLLFGVPPSWtllllplaLLLLLLFGLGLGLLLAALnvfFRDVQQIVGLLLQLL-----FFLSP 186
|
170 180 190
....*....|....*....|....*....|...
gi 344304674 655 VMYTgfvitTKEMLGWARWINYINPVAYVFESF 687
Cdd:COG1682 187 VFYP-----LSTLPEPLRWLLLLNPLTHIIELF 214
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
864-1069 |
5.69e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 46.67 E-value: 5.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLsdrhtVGV--ITDGVKMVNGHSLDSS----FQRSIGYV-QQQDLHLQTS 936
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLM-----IGIekVKSGEIFYNNQAITDDnfekLRKHIGIVfQNPDNQFVGS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 937 TVREALKFSAylrQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTS 1016
Cdd:PRK13648 100 IVKYDVAFGL---ENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGG----QKQRVAIAGVLALNPSVII-LDEATS 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1017 GLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSALLltEFDRLLFLQEGgqTVY 1069
Cdd:PRK13648 172 MLDPDARQNLLDLVRKVkSEHNITIISITHDLSEAM--EADHVIVMNKG--TVY 221
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
877-1044 |
6.26e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 47.72 E-value: 6.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 877 TALMGATGAGKTTLLNCL-------SDRHTV------GVITD------------GVKMVN--------GHSLDSS-FQ-- 920
Cdd:PTZ00265 1197 TAIVGETGSGKSTVMSLLmrfydlkNDHHIVfknehtNDMTNeqdyqgdeeqnvGMKNVNefsltkegGSGEDSTvFKns 1276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 921 ------------------RSIGYVQQQDLHLQTSTVREALKFSaylRQSNTTPDKE---KDAYVDYIIDLLEmSEYaDAM 979
Cdd:PTZ00265 1277 gkilldgvdicdynlkdlRNLFSIVSQEPMLFNMSIYENIKFG---KEDATREDVKracKFAAIDEFIESLP-NKY-DTN 1351
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 980 VGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTI 1044
Cdd:PTZ00265 1352 VGPYGKSLSGGQKQRIAIARALLREPKILL-LDEATSSLDSNSEKLIEKTIVDIKDKADKTIITI 1415
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
848-1064 |
6.42e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 46.65 E-value: 6.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 848 RDLTYEIRiKKEDRIILDHVDGWVKPGEITALMGATGAGKTT---LLNCLSDRHTVGVITDGVKMVNGHSLDssFQRSIG 924
Cdd:PRK13650 8 KNLTFKYK-EDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTtvrLIDGLLEAESGQIIIDGDLLTEENVWD--IRHKIG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 925 YV-QQQDLHLQTSTVREALKFSAylrQSNTTPDKEKDAYVDYIIDLLEMSEYADAmvgvAGSGLNIEQRKRLTIGVELVA 1003
Cdd:PRK13650 85 MVfQNPDNQFVGATVEDDVAFGL---ENKGIPHEEMKERVNEALELVGMQDFKER----EPARLSGGQKQRVAIAGAVAM 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 1004 KPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:PRK13650 158 RPKIII-LDEATSMLDPEGRLELIKTIKGIrDDYQMTVISITHDLDEVALS--DRVLVMKNG 216
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
149-400 |
7.05e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 46.31 E-value: 7.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 149 DKSRYFDILKPMDGL---LRPGELTVVLGRPGAGCSTLLKtlAVNTYGfqvDKDSKVSYDGltpdeiEKHYRGDVIYSAE 225
Cdd:PRK14239 10 DLSVYYNKKKALNSVsldFYPNEITALIGPSGSGKSTLLR--SINRMN---DLNPEVTITG------SIVYNGHNIYSPR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 226 TD---------------EHFPqLTVGDTLEFAARLRTPQNRGLgVDR--ETYAKHmASVYMATYGILrqrntpvgNEFVP 288
Cdd:PRK14239 79 TDtvdlrkeigmvfqqpNPFP-MSIYENVVYGLRLKGIKDKQV-LDEavEKSLKG-ASIWDEVKDRL--------HDSAL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 289 GCSGGERKRVSIAEVSLSGANIQCWDNATRGLD---AATALEFIRALKTSSAVLDVTpviaiyQCSQDAYDLFDNVSVLY 365
Cdd:PRK14239 148 GLSGGQQQRVCIARVLATSPKIILLDEPTSALDpisAGKIEETLLGLKDDYTMLLVT------RSMQQASRISDRTGFFL 221
|
250 260 270
....*....|....*....|....*....|....*
gi 344304674 366 GGHQIFFgkaNKAKEYFTNmgwycPERQTTADFLT 400
Cdd:PRK14239 222 DGDLIEY---NDTKQMFMN-----PKHKETEDYIS 248
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
864-1064 |
8.04e-05 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 47.13 E-value: 8.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCL----SDRHTVGVITDGvKMVNGHSLDSSFQRSIGYVQQQ--------DL 931
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALfgayPGKFEGNVFING-KPVDIRNPAQAIRAGIAMVPEDrkrhgivpIL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLQTSTVREALKFSAYLRQSNTTpdKEKDAYVDYIIDLLEMSEYADAMVGvagsGLNIEQRKRLTIGVELVAKPKLLLfL 1011
Cdd:TIGR02633 355 GVGKNITLSVLKSFCFKMRIDAA--AELQIIGSAIQRLKVKTASPFLPIG----RLSGGNQQKAVLAKMLLTNPRVLI-L 427
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 344304674 1012 DEPTSGLDSQTAWSICKLMRKLADHGQAILcTIHQPSALLLTEFDRLLFLQEG 1064
Cdd:TIGR02633 428 DEPTRGVDVGAKYEIYKLINQLAQEGVAII-VVSSELAEVLGLSDRVLVIGEG 479
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
874-1033 |
9.49e-05 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 45.75 E-value: 9.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 874 GEITALMGATGAGKTTLLNCLSDRHTVG---VITDGVKMvnGHSLDSSFQRSIGYVQQQDLHLQTSTVREALKFSAYLRQ 950
Cdd:PRK10253 33 GHFTAIIGPNGCGKSTLLRTLSRLMTPAhghVWLDGEHI--QHYASKEVARRIGLLAQNATTPGDITVQELVARGRYPHQ 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 951 SNTTP-DKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKL 1029
Cdd:PRK10253 111 PLFTRwRKEDEEAVTKAMQATGITHLADQSVDTLSGG----QRQRAWIAMVLAQETAIML-LDEPTTWLDISHQIDLLEL 185
|
....
gi 344304674 1030 MRKL 1033
Cdd:PRK10253 186 LSEL 189
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
854-1019 |
9.54e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 47.09 E-value: 9.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 854 IRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRhtvgVITDGvkmvNGHSLDSSFQrsIGYVQQQDLHL 933
Cdd:PRK10636 7 LQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNE----ISADG----GSYTFPGNWQ--LAWVNQETPAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 934 QTSTV-------REALKFSAYLRQSNTTPDKEKDAYVDYIIDLLEM----SEYADAMVGVAGSGLNIEQ---------RK 993
Cdd:PRK10636 77 PQPALeyvidgdREYRQLEAQLHDANERNDGHAIATIHGKLDAIDAwtirSRAASLLHGLGFSNEQLERpvsdfsggwRM 156
|
170 180
....*....|....*....|....*.
gi 344304674 994 RLTIGVELVAKPKLLLfLDEPTSGLD 1019
Cdd:PRK10636 157 RLNLAQALICRSDLLL-LDEPTNHLD 181
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
871-1064 |
1.12e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 46.89 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 871 VKPGEITALMGATGAGKTTLLNCLsdrHTVGVITDGVKMVNGHSLD----SSFQRSIGYVQQQDLhLQTSTVREALK-FS 945
Cdd:PLN03232 1259 VSPSEKVGVVGRTGAGKSSMLNAL---FRIVELEKGRIMIDDCDVAkfglTDLRRVLSIIPQSPV-LFSGTVRFNIDpFS 1334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 946 AYlrqsnTTPDKEKDAYVDYIIDLLEMSEYA-DAMVGVAGSGLNIEQRKRLTIGVELVAKPKlLLFLDEPTSGLDSQTAW 1024
Cdd:PLN03232 1335 EH-----NDADLWEALERAHIKDVIDRNPFGlDAEVSEGGENFSVGQRQLLSLARALLRRSK-ILVLDEATASVDVRTDS 1408
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 344304674 1025 SICKLMRKlADHGQAILCTIHQPSALLltEFDRLLFLQEG 1064
Cdd:PLN03232 1409 LIQRTIRE-EFKSCTMLVIAHRLNTII--DCDKILVLSSG 1445
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
864-1064 |
1.24e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 45.77 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNClsdrhTVGVITD--GVKMVNGHSLDSS---------FQRSIGYV-QQQDL 931
Cdd:PRK13645 27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQL-----TNGLIISetGQTIVGDYAIPANlkkikevkrLRKEIGLVfQFPEY 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 932 HLQTSTVREALKFSAYlrqsNTTPDKEkDAYvDYIIDLLEMSEYADAMVGVAGSGLNIEQRKRLTIGvELVAKPKLLLFL 1011
Cdd:PRK13645 102 QLFQETIEKDIAFGPV----NLGENKQ-EAY-KKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALA-GIIAMDGNTLVL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1012 DEPTSGLDSQTAWSICKLMRKL-ADHGQAILCTIHQPSALLLTEfDRLLFLQEG 1064
Cdd:PRK13645 175 DEPTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIA-DEVIVMHEG 227
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
164-303 |
1.37e-04 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 45.15 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDG-----LTPDEIEKHyRGdVIysaetdehfPQLTvgdT 238
Cdd:PRK13548 25 LRPGEVVAILGPNGAGKSTLLRALS----GELSPDSGEVRLNGrpladWSPAELARR-RA-VL---------PQHS---S 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 239 LEFAARL-------RTPQNRGLGVDRETYAKHMASVYMATygiLRQRntpvgneFVPGCSGGERKRVSIAEV 303
Cdd:PRK13548 87 LSFPFTVeevvamgRAPHGLSRAEDDALVAAALAQVDLAH---LAGR-------DYPQLSGGEQQRVQLARV 148
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
861-1064 |
1.37e-04 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 46.46 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 861 RIILDHVDGWVKPGEITALMGATGAGKTTLLNCL----SDRHTVGVITDGVKMVNGHSLDSsFQRSIGYV----QQQDLH 932
Cdd:PRK13549 275 IKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLfgayPGRWEGEIFIDGKPVKIRNPQQA-IAQGIAMVpedrKRDGIV 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 933 LQTStVREALKFSAYLRQSN-TTPDKEKD-AYVDYIIDLLEMsEYADAMVGVAG-SGLNieQRKRLtIGVELVAKPKLLl 1009
Cdd:PRK13549 354 PVMG-VGKNITLAALDRFTGgSRIDDAAElKTILESIQRLKV-KTASPELAIARlSGGN--QQKAV-LAKCLLLNPKIL- 427
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 1010 FLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIHQ-PSALLLTefDRLLFLQEG 1064
Cdd:PRK13549 428 ILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSElPEVLGLS--DRVLVMHEG 481
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
863-1046 |
1.47e-04 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 46.20 E-value: 1.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 863 ILDHVDGWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVIT--DGVKMVNGHSL-----DSSFQRSIGYVQQQDLHLQT 935
Cdd:PRK15439 26 VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIA-----GIVPpdSGTLEIGGNPCarltpAKAHQLGIYLVPQEPLLFPN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 936 STVREALKFSAYLRQSNTTPDKEKDAYVDYIIDlLEMSeyadamvgvAGSgLNIEQRKRLTIGVELVAKPKLLLfLDEPT 1015
Cdd:PRK15439 101 LSVKENILFGLPKRQASMQKMKQLLAALGCQLD-LDSS---------AGS-LEVADRQIVEILRGLMRDSRILI-LDEPT 168
|
170 180 190
....*....|....*....|....*....|.
gi 344304674 1016 SGLDSQTAWSICKLMRKLADHGQAILCTIHQ 1046
Cdd:PRK15439 169 ASLTPAETERLFSRIRELLAQGVGIVFISHK 199
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
830-1064 |
1.53e-04 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 45.28 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 830 IVELSENGLTGENETFLWRDLTyeIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTL---LNCLSDRHTVGVITDG 906
Cdd:cd03288 5 ISGSSNSGLVGLGGEIKIHDLC--VRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLslaFFRMVDIFDGKIVIDG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 907 VKM--VNGHSLdssfqRSIGYVQQQDLHLQTSTVREALkfsaylrqsnttpDKEKDAYVDYIIDLLEMSEYA-------- 976
Cdd:cd03288 83 IDIskLPLHTL-----RSRLSIILQDPILFSGSIRFNL-------------DPECKCTDDRLWEALEIAQLKnmvkslpg 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 977 --DAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICK-LMRKLADhgQAILCTIHQPSALLlt 1053
Cdd:cd03288 145 glDAVVTEGGENFSVGQRQLFCLARAFVRKSSILI-MDEATASIDMATENILQKvVMTAFAD--RTVVTIAHRVSTIL-- 219
|
250
....*....|.
gi 344304674 1054 EFDRLLFLQEG 1064
Cdd:cd03288 220 DADLVLVLSRG 230
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
864-1039 |
1.66e-04 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 46.08 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVG-----VITDGVKMVNGHSLDSSfQRSIGYVQQQDLHLQTSTV 938
Cdd:PRK13549 21 LDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGtyegeIIFEGEELQASNIRDTE-RAGIAIIHQELALVKELSV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 939 REALKFSAYLrqsntTPDKekdayvdyIIDLLEMSEYADAMVGVAGSGLNIEQR-KRLTIG----VEL---VAKPKLLLF 1010
Cdd:PRK13549 100 LENIFLGNEI-----TPGG--------IMDYDAMYLRAQKLLAQLKLDINPATPvGNLGLGqqqlVEIakaLNKQARLLI 166
|
170 180
....*....|....*....|....*....
gi 344304674 1011 LDEPTSGLDSQTAWSICKLMRKLADHGQA 1039
Cdd:PRK13549 167 LDEPTASLTESETAVLLDIIRDLKAHGIA 195
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
859-1050 |
2.56e-04 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 45.56 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 859 EDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL----SDRHTVGVITDGVKM------------------VNGHSLD 916
Cdd:TIGR03269 11 DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrgmdQYEPTSGRIIYHVALcekcgyverpskvgepcpVCGGTLE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 917 S--------------SFQRSIGYVQQQDLHL---QT--STVREALKFSAYlrqsnttpdKEKDAyVDYIIDLLEMSEYAD 977
Cdd:TIGR03269 91 PeevdfwnlsdklrrRIRKRIAIMLQRTFALygdDTvlDNVLEALEEIGY---------EGKEA-VGRAVDLIEMVQLSH 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344304674 978 AMVGVAgSGLNIEQRKRLTIGVELVAKPkLLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIHQPSAL 1050
Cdd:TIGR03269 161 RITHIA-RDLSGGEKQRVVLARQLAKEP-FLFLADEPTGTLDPQTAKLVHNALEEAVkASGISMVLTSHWPEVI 232
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
164-332 |
2.56e-04 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 44.02 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLTPDEIEKHYRGDVIYSAETDEHFPQLTVGDTLEFAA 243
Cdd:cd03231 23 LAAGEALQVTGPNGSGKTTLLRILA----GLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTTLSVLENLRFWH 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 244 RLRtpqnrglgvDRETYAKHMASVYMATYGilrqrNTPVGNefvpgCSGGERKRVSIAEVSLSGANIQCWDNATRGLDAA 323
Cdd:cd03231 99 ADH---------SDEQVEEALARVGLNGFE-----DRPVAQ-----LSAGQQRRVALARLLLSGRPLWILDEPTTALDKA 159
|
....*....
gi 344304674 324 TALEFIRAL 332
Cdd:cd03231 160 GVARFAEAM 168
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
164-324 |
3.02e-04 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 44.31 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 164 LRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGlTPDEIEKHYRGDVIysaETDEHFPQLTVGDTLEFAA 243
Cdd:PRK11248 24 LESGELLVVLGPSGCGKTTLLNLIA----GFVPYQHGSITLDG-KPVEGPGAERGVVF---QNEGLLPWRNVQDNVAFGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 244 RLRtpqnrglGVD---RETYAKHM-ASVYMATYgilrqrntpvGNEFVPGCSGGERKRVSIAEVSLSGANIQCWDNATRG 319
Cdd:PRK11248 96 QLA-------GVEkmqRLEIAHQMlKKVGLEGA----------EKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158
|
....*
gi 344304674 320 LDAAT 324
Cdd:PRK11248 159 LDAFT 163
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
144-399 |
3.93e-04 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 43.88 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 144 YFRKDDKSryfdILKPMDGLLRPGELTVVLGRPGAGCSTLLKTL--AVNTYGFQVDKDSKVSYDGLTPDEIEK-HYRGDV 220
Cdd:PRK14246 17 YLYINDKA----ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLnrLIEIYDSKIKVDGKVLYFGKDIFQIDAiKLRKEV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 221 IYSAETDEHFPQLTVGDTLEFAARlrtpqNRGLGVDRETyaKHMASVYMATYGILRQ----RNTPVGNefvpgCSGGERK 296
Cdd:PRK14246 93 GMVFQQPNPFPHLSIYDNIAYPLK-----SHGIKEKREI--KKIVEECLRKVGLWKEvydrLNSPASQ-----LSGGQQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 297 RVSIAEVSLSGANIQCWDNATRGLDAATAL---EFIRALKTSSAVLDVTpviaiyQCSQDAYDLFDNVSVLYGGHQIFFG 373
Cdd:PRK14246 161 RLTIARALALKPKVLLMDEPTSMIDIVNSQaieKLITELKNEIAIVIVS------HNPQQVARVADYVAFLYNGELVEWG 234
|
250 260
....*....|....*....|....*.
gi 344304674 374 KANkakEYFTNmgwycPERQTTADFL 399
Cdd:PRK14246 235 SSN---EIFTS-----PKNELTEKYV 252
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
864-1064 |
3.96e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 44.21 E-value: 3.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTL---LNCLSDRHTVGVITDGVKMVNGHSLdSSFQRSIGYV-QQQDLHLQTSTVR 939
Cdd:PRK13644 18 LENINLVIKKGEYIGIIGKNGSGKSTLalhLNGLLRPQKGKVLVSGIDTGDFSKL-QGIRKLVGIVfQNPETQFVGRTVE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 940 EALKFSAylrQSNTTPDKEKDAYVDYIIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELVAKPKLLLFlDEPTSGLD 1019
Cdd:PRK13644 97 EDLAFGP---ENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGG----QGQCVALAGILTMEPECLIF-DEVTSMLD 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 344304674 1020 SQTAWSICKLMRKLADHGQAILCTIHQPSALLLTefDRLLFLQEG 1064
Cdd:PRK13644 169 PDSGIAVLERIKKLHEKGKTIVYITHNLEELHDA--DRIIVMDRG 211
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
156-300 |
5.08e-04 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 43.16 E-value: 5.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVntygfQVDKDS-KVSYDG-----LTPDEiekhYRGDVIYSAETDEH 229
Cdd:PRK10247 22 ILNNISFSLRAGEFKLITGPSGCGKSTLLKIVAS-----LISPTSgTLLFEGedistLKPEI----YRQQVSYCAQTPTL 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 344304674 230 FPQlTVGDTLEFAARLRTPQnrglgVDRETYAKHMASVYMATYgILRQRntpvgnefVPGCSGGERKRVSI 300
Cdd:PRK10247 93 FGD-TVYDNLIFPWQIRNQQ-----PDPAIFLDDLERFALPDT-ILTKN--------IAELSGGEKQRISL 148
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
852-1064 |
5.09e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.94 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 852 YEIRIKKEDRIILDHVDGWVKPGEITALMGATGAGKTTLLNCL---SDRHTVGVITDGVKMVNGHSLDSSFQRSIgyvQQ 928
Cdd:TIGR00957 1290 YCLRYREDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLfriNESAEGEIIIDGLNIAKIGLHDLRFKITI---IP 1366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 929 QDLHLQTSTVREALK-FSAYlrqsnttpdkeKDAYVDYIIDLLEMSEYADAM-------VGVAGSGLNIEQRKRLTIGVE 1000
Cdd:TIGR00957 1367 QDPVLFSGSLRMNLDpFSQY-----------SDEEVWWALELAHLKTFVSALpdkldheCAEGGENLSVGQRQLVCLARA 1435
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 344304674 1001 LVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGqAILCTIHQPSALLltEFDRLLFLQEG 1064
Cdd:TIGR00957 1436 LLRKTKILV-LDEATAAVDLETDNLIQSTIRTQFEDC-TVLTIAHRLNTIM--DYTRVIVLDKG 1495
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
957-1043 |
5.21e-04 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 43.96 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 957 KEKDAYVDYIIDLLEMSEYAdamvGVAGSGLNIEQRKRLTIGVELVAKPKLLlFLDEPTSGLDSQTAWSICKLMRKLADH 1036
Cdd:NF000106 119 KDARARADELLERFSLTEAA----GRAAAKYSGGMRRRLDLAASMIGRPAVL-YLDEPTTGLDPRTRNEVWDEVRSMVRD 193
|
....*..
gi 344304674 1037 GQAILCT 1043
Cdd:NF000106 194 GATVLLT 200
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
823-1022 |
5.78e-04 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 44.41 E-value: 5.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 823 SDFEKKEIVELsengltgENETFLWRDLT-YEIRIkkeDRIILDHVDGW---VKPGEITALMGATGAGKTTLLNCL---- 894
Cdd:TIGR03269 265 SEVEKECEVEV-------GEPIIKVRNVSkRYISV---DRGVVKAVDNVsleVKEGEIFGIVGTSGAGKTTLSKIIagvl 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 895 ---SDRHTVGVITDGVKMVN-GHSLDSSFQRSIGYVQQQDLHLQTSTVREALKFSAYLRqsntTPD---KEKDAYVDYII 967
Cdd:TIGR03269 335 eptSGEVNVRVGDEWVDMTKpGPDGRGRAKRYIGILHQEYDLYPHRTVLDNLTEAIGLE----LPDelaRMKAVITLKMV 410
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 344304674 968 DLLEmsEYADAMVGVAGSGLNIEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQT 1022
Cdd:TIGR03269 411 GFDE--EKAEEILDKYPDELSEGERHRVALAQVLIKEPRIVI-LDEPTGTMDPIT 462
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
156-188 |
6.89e-04 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 43.28 E-value: 6.89e-04
10 20 30
....*....|....*....|....*....|...
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLA 188
Cdd:PRK13547 16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALA 48
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
165-338 |
8.62e-04 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 42.36 E-value: 8.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 165 RPGELTVVLGRPGAGCSTLLKTLAVNT---------YGFQVDKDskvsydgltPDEIEKHYrGDVIYSAETDehfPQLTV 235
Cdd:cd03265 24 RRGEIFGLLGPNGAGKTTTIKMLTTLLkptsgratvAGHDVVRE---------PREVRRRI-GIVFQDLSVD---DELTG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 GDTLEFAARLRtpqnrglGVDRETYAKHMASVyMATYGILRQRNTPVGNEfvpgcSGGERKRVSIAEVSLSGANIQCWDN 315
Cdd:cd03265 91 WENLYIHARLY-------GVPGAERRERIDEL-LDFVGLLEAADRLVKTY-----SGGMRRRLEIARSLVHRPEVLFLDE 157
|
170 180
....*....|....*....|....*.
gi 344304674 316 ATRGLDAATAL---EFIRALKTSSAV 338
Cdd:cd03265 158 PTIGLDPQTRAhvwEYIEKLKEEFGM 183
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
869-1039 |
1.05e-03 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 42.40 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 869 GWVKPGEITALMGATGAGKTTLLNCLSdrhtvGVItdgvKMVNGHSLdsSFQRSIGYVQQQDLHLQTSTVREALkfsayl 948
Cdd:cd03237 20 GSISESEVIGILGPNGIGKTTFIKMLA-----GVL----KPDEGDIE--IELDTVSYKPQYIKADYEGTVRDLL------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 949 rqSNTTPDKEKDAYVDY-IIDLLEMSEYADAMVGVAGSGlnieQRKRLTIGVELvAKPKLLLFLDEPTSGLDSQTAWSIC 1027
Cdd:cd03237 83 --SSITKDFYTHPYFKTeIAKPLQIEQILDREVPELSGG----ELQRVAIAACL-SKDADIYLLDEPSAYLDVEQRLMAS 155
|
170
....*....|..
gi 344304674 1028 KLMRKLADHGQA 1039
Cdd:cd03237 156 KVIRRFAENNEK 167
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
822-1076 |
1.24e-03 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 43.48 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 822 NSDFE---KKEIVELSENGLTGEN-ETFLWRDLTYEIRIKKEDRIILDhVDGWVKPGEITALMGATGAGKTTLLNCLSDR 897
Cdd:PTZ00265 356 NSLYEiinRKPLVENNDDGKKLKDiKKIQFKNVRFHYDTRKDVEIYKD-LNFTLTEGKTYAFVGESGCGKSTILKLIERL 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 898 HTVgviTDGVKMVN-GHSLDS---SFQRS-IGYVQQQDLhLQTSTVREALKFSAY----------------------LRQ 950
Cdd:PTZ00265 435 YDP---TEGDIIINdSHNLKDinlKWWRSkIGVVSQDPL-LFSNSIKNNIKYSLYslkdlealsnyynedgndsqenKNK 510
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 951 SNTTPDKEKDAYVDYI-----IDLLEM-SEYA---------------------------DAMVGVAGSGLNIEQRKRLTI 997
Cdd:PTZ00265 511 RNSCRAKCAGDLNDMSnttdsNELIEMrKNYQtikdsevvdvskkvlihdfvsalpdkyETLVGSNASKLSGGQKQRISI 590
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 998 GVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTI-HQPSALLLTEFDRLLFLQEGGQTVYFGDLGEN 1076
Cdd:PTZ00265 591 ARAIIRNPKILI-LDEATSSLDNKSEYLVQKTINNLKGNENRITIIIaHRLSTIRYANTIFVLSNRERGSTVDVDIIGED 669
|
|
| YadH |
COG0842 |
ABC-type multidrug transport system, permease component [Defense mechanisms]; |
616-687 |
1.30e-03 |
|
ABC-type multidrug transport system, permease component [Defense mechanisms];
Pssm-ID: 440604 [Multi-domain] Cd Length: 200 Bit Score: 41.72 E-value: 1.30e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344304674 616 WLMAIWCTLIMSHLFRCIGSLVTTVA----QAMTPATVMLLAMVMYTGFVITTKEMLGWARWINYINPVAYVFESF 687
Cdd:COG0842 84 LLLLLLVLLLFALAFSGLGLLISTLArsqeQASAISNLVILPLTFLSGAFFPIESLPGWLQAIAYLNPLTYFVEAL 159
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
156-332 |
1.31e-03 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 41.53 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAVNtygfqvdkdskvsydgLTPDEiekhyrGDVIYSaetdehfpqltv 235
Cdd:cd03247 17 VLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGD----------------LKPQQ------GEITLD------------ 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 gdtlefaarlrtpqnrglGVDRETYAKHMASvymaTYGILRQR----NTPVGNEFVPGCSGGERKRVSIAEVSLSGANIQ 311
Cdd:cd03247 63 ------------------GVPVSDLEKALSS----LISVLNQRpylfDTTLRNNLGRRFSGGERQRLALARILLQDAPIV 120
|
170 180
....*....|....*....|.
gi 344304674 312 CWDNATRGLDAATALEFIRAL 332
Cdd:cd03247 121 LLDEPTVGLDPITERQLLSLI 141
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
864-895 |
1.35e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 43.24 E-value: 1.35e-03
10 20 30
....*....|....*....|....*....|..
gi 344304674 864 LDHVDGWVKPGEITALMGATGAGKTTLLNCLS 895
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLS 48
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
156-373 |
1.86e-03 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 40.88 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 156 ILKPMDGLLRPGELTVVLGRPGAGCSTLLKTLAvntyGFQVDKDSKVSYDGLtpdeiekhyrgdviysaetdehfpqltv 235
Cdd:cd03214 14 VLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLA----GLLKPSSGEILLDGK---------------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 236 gDTLEFAARLRtpqnrglgvdretyAKHMASV--YMATYGI--LRQRNTpvgNEFvpgcSGGERKRVSIAEVSLSGANIQ 311
Cdd:cd03214 62 -DLASLSPKEL--------------ARKIAYVpqALELLGLahLADRPF---NEL----SGGERQRVLLARALAQEPPIL 119
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 312 CWDNATRGLDAATALEFIRALKTSSAVLDVTPVIAIYQCSQdAYDLFDNVSVLYGGHQIFFG 373
Cdd:cd03214 120 LLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNL-AARYADRVILLKDGRIVAQG 180
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
157-320 |
2.94e-03 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 42.08 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 157 LKPMDGLLRPGELTVVLGRPGAGCSTLLKTLA---VNTYGFQVDKDskVSYDGLTPDEIEKHYRGdVIYSaetdehfpQL 233
Cdd:PRK09700 21 LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSgihEPTKGTITINN--INYNKLDHKLAAQLGIG-IIYQ--------EL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 234 TVGDTLEFAARL---RTPQNRGLGVDRETYAK--HMASVYMATYGILRQRNTPVGNefvpgCSGGERKRVSIAEVSLSGA 308
Cdd:PRK09700 90 SVIDELTVLENLyigRHLTKKVCGVNIIDWREmrVRAAMMLLRVGLKVDLDEKVAN-----LSISHKQMLEIAKTLMLDA 164
|
170
....*....|..
gi 344304674 309 NIQCWDNATRGL 320
Cdd:PRK09700 165 KVIIMDEPTSSL 176
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
991-1033 |
3.03e-03 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 42.00 E-value: 3.03e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 344304674 991 QRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 1033
Cdd:PRK15134 430 QRQRIAIARALILKPSLII-LDEPTSSLDKTVQAQILALLKSL 471
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
291-403 |
3.30e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 41.35 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344304674 291 SGGERKRVSIAEVSLSGANIQCWDNATRGLDAATALEFIRALKTSSAVLDVtpVIAIYQCSQDAYDLFDNVSVLYGGHQI 370
Cdd:PRK13641 147 SGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHT--VILVTHNMDDVAEYADDVLVLEHGKLI 224
|
90 100 110
....*....|....*....|....*....|....*..
gi 344304674 371 ffgKANKAKEYFTNMGW----YCPErQTTADFLTSLT 403
Cdd:PRK13641 225 ---KHASPKEIFSDKEWlkkhYLDE-PATSRFASKLE 257
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
291-346 |
4.98e-03 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 41.49 E-value: 4.98e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344304674 291 SGGERKRVSIAEVSLSGANIQCWDNATRGLDAAT------ALEFIRALKTssavldvTPVIA 346
Cdd:PRK13657 473 SGGERQRLAIARALLKDPPILILDEATSALDVETeakvkaALDELMKGRT-------TFIIA 527
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
991-1037 |
5.91e-03 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 41.21 E-value: 5.91e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 344304674 991 QRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL-ADHG 1037
Cdd:COG4172 430 QRQRIAIARALILEPKLLV-LDEPTSALDVSVQAQILDLLRDLqREHG 476
|
|
| CpaF |
COG4962 |
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ... |
881-895 |
6.14e-03 |
|
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 443988 [Multi-domain] Cd Length: 386 Bit Score: 40.92 E-value: 6.14e-03
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
867-913 |
9.14e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 38.90 E-value: 9.14e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 344304674 867 VDGWVKPGEITALMGATGAGKTTLLNCLSDRHTVGVITDGVKMVNGH 913
Cdd:pfam13481 26 IKGLLPAGGLGLLAGAPGTGKTTLALDLAAAVATGKPWLGGPRVPEQ 72
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
860-891 |
9.15e-03 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 39.75 E-value: 9.15e-03
10 20 30
....*....|....*....|....*....|..
gi 344304674 860 DRIILDHVDGWVKPGEITALMGATGAGKTTLL 891
Cdd:PRK11831 19 NRCIFDNISLTVPRGKITAIMGPSGIGKTTLL 50
|
|
| |
