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Conserved domains on  [gi|344190015|gb|AEM97830|]
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NADH dehydrogenase 5, partial (mitochondrion) [Gomphocerus sibiricus]

Protein Classification

NADH dehydrogenase subunit 5( domain architecture ID 11475935)

NADH dehydrogenase subunit 5 (ND5/NADH5) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain; the immediate electron acceptor for the enzyme is believed to be ubiquinone

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND5 MTH00165
NADH dehydrogenase subunit 5; Provisional
 1-213 5.70e-72

NADH dehydrogenase subunit 5; Provisional


:

Pssm-ID: 214444 [Multi-domain]  Cd Length: 573  Bit Score: 228.49  E-value: 5.70e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00165 309 FLCAGSIIHNMSNSQDIRFMGGLSNFMPLTSSCFNISNLSLCGFPFLSGFYSKDLILEMVSMSNLNFFIFFLFFFSTGLT 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00165 389 VSYSFRLIYYSMSGDFNLKSLNNLSDESKFMLKSMILLLFMSIFGGSMLSWLIFPEPYMICLPFYLKLLTLFVILLGGWL 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFSYDLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00165 469 GYELSLMSLSYNLKSLKNYKLSSFLGSMWFMPFLSTYGISYYPLNLGSLSLKS 521
 
Name Accession Description Interval E-value
ND5 MTH00165
NADH dehydrogenase subunit 5; Provisional
 1-213 5.70e-72

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214444 [Multi-domain]  Cd Length: 573  Bit Score: 228.49  E-value: 5.70e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00165 309 FLCAGSIIHNMSNSQDIRFMGGLSNFMPLTSSCFNISNLSLCGFPFLSGFYSKDLILEMVSMSNLNFFIFFLFFFSTGLT 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00165 389 VSYSFRLIYYSMSGDFNLKSLNNLSDESKFMLKSMILLLFMSIFGGSMLSWLIFPEPYMICLPFYLKLLTLFVILLGGWL 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFSYDLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00165 469 GYELSLMSLSYNLKSLKNYKLSSFLGSMWFMPFLSTYGISYYPLNLGSLSLKS 521
NADH5_C pfam06455
NADH dehydrogenase subunit 5 C-terminus; This family represents the C-terminal region of ...
 83-213 1.21e-26

NADH dehydrogenase subunit 5 C-terminus; This family represents the C-terminal region of several NADH dehydrogenase subunit 5 proteins and is found in conjunction with pfam00361 and pfam00662.


Pssm-ID: 368917 [Multi-domain]  Cd Length: 181  Bit Score: 100.70  E-value: 1.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   83 YSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYLGY 162
Cdd:pfam06455   1 YSFRLIYYVMTGSPRFSSLSPINENNPIMINPIKRLAIGSIIGGSLLSWLIFPKPPMMTMPLYLKLLALLVTILGLLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 344190015  163 YFSNTNFSYDLFSLNFlSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:pfam06455  81 ELSNLSNKQLKKSLNF-NLHSFSGSMWFFPNLSHRLIPKLSLKLGQKLAKQ 130
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 1-164 6.62e-20

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 87.13  E-value: 6.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLkDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILE-MVCLSWINCLIFFLYFISTGL 79
Cdd:COG1009  341 FLGAGSVIHAT-GTRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEaALEAGGLGPLLLAVALLGAFL 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  80 TACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWL---------IFPIPYMIVLPYYLSFLT 150
Cdd:COG1009  420 TAFYSFRLFFLVFFGKPRPKTPKHPHESPWLMTLPLVVLAVLSLVLGLLLPGLlegllapaaVLGGELHLAHGLLLNALP 499

                        170
                 ....*....|....
gi 344190015 151 IFTVVLGAYLGYYF 164
Cdd:COG1009  500 LLLSLLGIALGYLL 513
 
Name Accession Description Interval E-value
ND5 MTH00165
NADH dehydrogenase subunit 5; Provisional
 1-213 5.70e-72

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214444 [Multi-domain]  Cd Length: 573  Bit Score: 228.49  E-value: 5.70e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00165 309 FLCAGSIIHNMSNSQDIRFMGGLSNFMPLTSSCFNISNLSLCGFPFLSGFYSKDLILEMVSMSNLNFFIFFLFFFSTGLT 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00165 389 VSYSFRLIYYSMSGDFNLKSLNNLSDESKFMLKSMILLLFMSIFGGSMLSWLIFPEPYMICLPFYLKLLTLFVILLGGWL 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFSYDLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00165 469 GYELSLMSLSYNLKSLKNYKLSSFLGSMWFMPFLSTYGISYYPLNLGSLSLKS 521
ND5 MTH00209
NADH dehydrogenase subunit 5; Provisional
 1-213 5.59e-43

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177252 [Multi-domain]  Cd Length: 564  Bit Score: 151.72  E-value: 5.59e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00209 305 FICAGNIIHSHGHSQDIRMVGNLWYQMPITSICLNIANLSLCGIPFLAGFYSKDLILESMLESNMPIMTLILMFLSTSLT 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00209 385 AAYSMRLSYFSLWGPNSSKSLNSSFDQNKLNLKPMLVLTLGSITGGSVMSWVMVPSVNSVVLPWFLKLLPIMLILFGVLL 464

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFsydlFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00209 465 MYMVLKKNF----FLIKGYKVNYFLSQMWFLPDLSSQPVNKFTMKLSKTMLKL 513
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 1-213 4.24e-40

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 143.75  E-value: 4.24e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00207 309 FVCAGSLIHSHHHSQDLRTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESSLFYPHNSLMILMIFLATALT 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00207 389 AAYSTRFTLAVLWSPNSSSPYHHLEDEDKSLTTPMLLLTLGAITSGSALNWWLPTPQEEPILPLQYKLLPLLVVTLGALL 468

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFSYDLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00207 469 AWLFTTPNITKTPLLINNPLSHFASCLMWFLVPLSSQFIMSTPMNLSHNYLKL 521
ND5 MTH00151
NADH dehydrogenase subunit 5; Provisional
 1-213 4.78e-38

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214436 [Multi-domain]  Cd Length: 565  Bit Score: 138.05  E-value: 4.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00151 306 FLCAGSIIHSSSGTQDIRLLGSLFLSLPLTSGCLNISSLSLCGAPFLSGFYSKDLILESSLMSPTSLLMVLLMFVGVGLT 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00151 386 ALYSARLSFCLVWGSMKSSSLSSKSDEDFYVSLPMLLLSLGALIGGKLLQSLFEGFSEEFFLPSYLKLLIGFVILLGLFL 465

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 344190015 161 GYYFSNTNFsydlFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:MTH00151 466 SFGFWDSGF----SSSKMVKLSFFFSSMWFLSPLSSQPLKSLSLKLSNSSMKS 514
ND5 MTH00108
NADH dehydrogenase subunit 5; Provisional
 1-207 1.32e-30

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177170 [Multi-domain]  Cd Length: 602  Bit Score: 117.65  E-value: 1.32e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00108 340 FMCSGSIIHNLNDEQDIRKMGGLFKTLPFTSTALIIGSLALTGMPFLTGFYSKDLIIEAANTSYTNAWALLITLIATSLT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFP--IPYMiVLPYYLSFLTIFTVVLGA 158
Cdd:MTH00108 420 AAYSTRIIFFALLGQPRFPPLITINENNPLLINPIKRLLLGSIFAGFLISNNIPPttIPQM-TMPLYLKLTALAVTILGF 498

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 344190015 159 YLGYYFSNTnfSYDLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMG 207
Cdd:MTH00108 499 ILALELNLL--TNNLKFKYPSNTFKFSNMLGYFPTIMHRLPPYMNLTMS 545
ND5 MTH00208
NADH dehydrogenase subunit 5; Provisional
 1-202 1.03e-29

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177251 [Multi-domain]  Cd Length: 628  Bit Score: 115.45  E-value: 1.03e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00208 366 FLCSGSIIHSLNNEQDLRKMGGLSFLLPVTSSCIILGSLALMGTPFLAGFYSKDLILEAGLASISNLLSIILALIATLLT 445

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPyMIVLPYYLSFLTIFTVVLGAYL 160
Cdd:MTH00208 446 AVYSFRIIFFCFLNNPSFSPLSPISEENPNLTNPLLRLAIGTIISGWFFSNFVFNLP-PLTLPLILKSLPLIVTIIGAAF 524

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 344190015 161 GYYFSNtNFSYDLFSLNFLSL*SFSgsmWFMPYLSTGFISYL 202
Cdd:MTH00208 525 SFSFLL-SLSSNPINSNFFSFLSNQ---WFFVNISHSIIISF 562
ND5 MTH00004
NADH dehydrogenase subunit 5; Validated
 1-168 1.32e-29

NADH dehydrogenase subunit 5; Validated


Pssm-ID: 214398 [Multi-domain]  Cd Length: 602  Bit Score: 114.88  E-value: 1.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00004 339 FLCSGSIIHNLNNEQDIRKMGGLQKTLPITSSCLTIGNLALMGTPFLSGFYSKDTIIETLNTSYLNAWALLLTLLATSFT 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPI-PYMIVLPYYLSFLTIFTVVLGAY 159
Cdd:MTH00004 419 AAYSLRMILLVQTGFPRTPPTTPINENTPTIINPITRLALGSILAGLLISSTILPTkTPPMTMPTTTKLAALIVTILGIL 498


                 ....*....
gi 344190015 160 LGYYFSNTN 168
Cdd:MTH00004 499 LALELSNMT 507
ND5 MTH00211
NADH dehydrogenase subunit 5; Provisional
 1-207 3.64e-29

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214459 [Multi-domain]  Cd Length: 597  Bit Score: 113.51  E-value: 3.64e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00211 334 FMCSGSIIHGLNNEQDIRKMGGLSKNLPFTSSCLFLGSLALMGFPFLSGFFSKDLILESMNGSYLNAWALLLTLLATSLT 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIV-LPYYLSFLTIFTVVLGAY 159
Cdd:MTH00211 414 AAYSFRLIFLSLGGYPRFLSLSPINENYKLLKNPLKRLALGSILAGFIITSNLPPEKPEILsLPFLLKLMPLLVTIVGLL 493

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 344190015 160 LGYYFSNTnfsydLFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMG 207
Cdd:MTH00211 494 LGLELVNL-----THKQLKTSTLSFSNMLGYYPPIIHRLLPKLSLKWG 536
ND5 MTH00066
NADH dehydrogenase subunit 5; Provisional
 1-194 5.62e-28

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214416 [Multi-domain]  Cd Length: 598  Bit Score: 110.38  E-value: 5.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00066 337 FLCSGSIIHSLNDEQDIRKMGGLQKALPITTSCLTIGSLALTGTPFLAGFFSKDAIIEAMNTSNLNSWALILTLIATSFT 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIV-LPYYLSFLTIFTVVLGAY 159
Cdd:MTH00066 417 AVYSFRIIYFSSMKFPRSLPLSPINENNPLIINPIKRLAWGSIIAGLLIIFNILPMKPQILtMPTFMKLAALLVTLLGLL 496

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 344190015 160 LGYYFSNTNFSydlfSLNFLSL*SFSGSMWFMPYL 194
Cdd:MTH00066 497 IALDLAKITSK----TTPKTKMHSFSNLLAFFPTI 527
NADH5_C pfam06455
NADH dehydrogenase subunit 5 C-terminus; This family represents the C-terminal region of ...
 83-213 1.21e-26

NADH dehydrogenase subunit 5 C-terminus; This family represents the C-terminal region of several NADH dehydrogenase subunit 5 proteins and is found in conjunction with pfam00361 and pfam00662.


Pssm-ID: 368917 [Multi-domain]  Cd Length: 181  Bit Score: 100.70  E-value: 1.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   83 YSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGAYLGY 162
Cdd:pfam06455   1 YSFRLIYYVMTGSPRFSSLSPINENNPIMINPIKRLAIGSIIGGSLLSWLIFPKPPMMTMPLYLKLLALLVTILGLLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 344190015  163 YFSNTNFSYDLFSLNFlSL*SFSGSMWFMPYLSTGFISYLPLSMGY*SSKS 213
Cdd:pfam06455  81 ELSNLSNKQLKKSLNF-NLHSFSGSMWFFPNLSHRLIPKLSLKLGQKLAKQ 130
ND5 MTH00137
NADH dehydrogenase subunit 5; Provisional
 1-92 5.56e-26

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214428 [Multi-domain]  Cd Length: 611  Bit Score: 104.53  E-value: 5.56e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00137 345 FLCSGSIIHSLNDEQDIRKMGGLHHLTPFTSSCLTIGSLALTGTPFLAGFFSKDAIIEALNTSHLNAWALTLTLIATSFT 424

                         90
                 ....*....|...
gi 344190015  81 ACYSFRL-FYYSM 92
Cdd:MTH00137 425 AVYSLRVvFFVSM 437
ND5 MTH00210
NADH dehydrogenase subunit 5; Provisional
 1-208 6.10e-21

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177253 [Multi-domain]  Cd Length: 616  Bit Score: 90.07  E-value: 6.10e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00210 341 FLSAGSVIHAVSDEQDMRKMGGLIKSIPFTYVMILIGSLSLMGFPYLTGFYSKDLILELTYDKYYIAFAYWLGSFSALLT 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYSMSGDNNFYSSFSFN--DSSYFISFGMLSLLFVAVFGGSLLSWLIFPIPYMIVLPYYLSFLTIFTVVLGA 158
Cdd:MTH00210 421 AFYSIRLIYLTFITNTNSKKEVFIGvhESSWNITFPLLLLAFGSIFVGYLGKEVVLSNVIPPIVPNSIKMIPLLFSLLGA 500

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 344190015 159 YLGYYFSNTNFSYD------LFSLNFLSL*SFSGSMWFMPYLSTGFISYLPLSMGY 208
Cdd:MTH00210 501 LLAFVIYNSMVFLIkisrrgVSIRLYHVIYTFLNSAWQFNYVINHFIVKNIWKFGH 556
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 1-200 7.44e-21

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 89.75  E-value: 7.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00020 340 FLSAGSVIHALSDEQDMRKMGGLISFLPLTYIFFLIGSLSLMGFPYLTGFYSKDLILELAFGQYYLIFAYWLGCFSALLT 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  81 ACYSFRLFYYS-MSGDNNFYSSFSF-NDSSYFISFGMLSLLFVAVFGGSLLSWLIF--------PIPYMI-VLPYYLSFL 149
Cdd:MTH00020 420 AFYSIRLIYLTfLSNTNLKKAVFFHlHEGDWNLLLPLGILALGSIFVGYLAKEMIWsfqitlppIVPLSIkLLPVFLSLG 499

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 344190015 150 TIFTVVlgayLGYYFSNTNFSYdLFSLNFLSL*SFSGSMWFMPYLSTGFIS 200
Cdd:MTH00020 500 GIGLVI----ILYFYSSKTFRV-PFSFIGRNSYTFLGSAWQFNYILNYFLI 545
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 1-164 6.62e-20

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 87.13  E-value: 6.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLkDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILE-MVCLSWINCLIFFLYFISTGL 79
Cdd:COG1009  341 FLGAGSVIHAT-GTRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEaALEAGGLGPLLLAVALLGAFL 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015  80 TACYSFRLFYYSMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFGGSLLSWL---------IFPIPYMIVLPYYLSFLT 150
Cdd:COG1009  420 TAFYSFRLFFLVFFGKPRPKTPKHPHESPWLMTLPLVVLAVLSLVLGLLLPGLlegllapaaVLGGELHLAHGLLLNALP 499

                        170
                 ....*....|....
gi 344190015 151 IFTVVLGAYLGYYF 164
Cdd:COG1009  500 LLLSLLGIALGYLL 513
PRK06590 PRK06590
NADH:ubiquinone oxidoreductase subunit L; Reviewed
 1-88 1.19e-18

NADH:ubiquinone oxidoreductase subunit L; Reviewed


Pssm-ID: 235836 [Multi-domain]  Cd Length: 624  Bit Score: 83.67  E-value: 1.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEmVCLSWINCLIFFLYFISTGLT 80
Cdd:PRK06590 347 FLGAGSVIHAMHHEQDIRKMGGLRKKMPVTYATFLIGTLALIGIPPFAGFFSKDEILE-AAFANGHINLFVAGLVGAFLT 425


                 ....*...
gi 344190015  81 ACYSFRLF 88
Cdd:PRK06590 426 AFYSFRLI 433
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
1-95 4.62e-16

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 76.22  E-value: 4.62e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKD--------SQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSwiNCLIFFL 72
Cdd:PRK07376 357 FLGSGSVIHGMEEvvghdpvlAQDMRLMGGLRKYMPITAITFLIGCLAISGIPPFAGFWSKDEILGAAFEA--NPALWFV 434

                         90       100
                 ....*....|....*....|...
gi 344190015  73 YFISTGLTACYSFRLFYYSMSGD 95
Cdd:PRK07376 435 GFLTAGMTAFYMFRMYFLTFEGE 457
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-76 1.68e-09

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 56.17  E-value: 1.68e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 344190015    1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFIS 76
Cdd:pfam00361 216 FLCAGSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ndhF CHL00025
NADH dehydrogenase subunit 5
 1-113 2.71e-09

NADH dehydrogenase subunit 5


Pssm-ID: 214338 [Multi-domain]  Cd Length: 741  Bit Score: 56.05  E-value: 2.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNL--------KDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMvclSWINCLIF-F 71
Cdd:CHL00025 357 FLGSGSVIHSMepivgyspDKSQNMVLMGGLRKYMPITKTTFLLGTLSLCGIPPLACFWSKDEILND---SWLYSPIFaI 433

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 344190015  72 LYFISTGLTACYSFRLFYYSMSGD---NNFYSSFSFNDSSYFISF 113
Cdd:CHL00025 434 IAWSTAGLTAFYMFRIYLLTFEGHlrvHFQNYSGKKNSSFYSISL 478
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 1-59 3.12e-09

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 56.12  E-value: 3.12e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLK-DSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEM 59
Cdd:MTH00032 356 FLSAGSVIHSTTvDEQDMRKMGGLIHSIPFTYTMMLIGSFSIMGLPYLTGFYSKDLILEL 415
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-90 1.52e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 47.83  E-value: 1.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKdSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVcLSWINCLIFFLYFISTGLT 80
Cdd:COG0651  341 FLAAGAIERATG-TRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAA-LEAGAWLLAAVLLLSSLLT 418

                         90
                 ....*....|
gi 344190015  81 ACYSFRLFYY 90
Cdd:COG0651  419 LAYFVRIFGR 428
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-89 1.23e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 45.35  E-value: 1.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKdSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLyFISTGLT 80
Cdd:PRK12667 364 FLASGVFIHAAG-TRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVL-LIASAIS 441


                 ....*....
gi 344190015  81 ACYSFRLFY 89
Cdd:PRK12667 442 LVGYFRAWY 450
ND5 MTH00095
NADH dehydrogenase subunit 5; Provisional
 1-152 2.73e-05

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177158 [Multi-domain]  Cd Length: 527  Bit Score: 44.14  E-value: 2.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:MTH00095 293 FMQVGYLIHSNFGQQDGRNYSNNGNLPMFIQLQLLVTLFCLCGLMFTSGMVSKELILELFFFNNYMIFFSLMFFFSVFLT 372

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 344190015  81 ACYSFRLFyysMSGDNNFYSSFSFNDSSYFISFGMLSLLFVAVFggsLLSWLIFPIPYMIVLPYYLSFLTIF 152
Cdd:MTH00095 373 FGYSYRLW---KSFFLSFSKVVNVYSSSVLMNFLSLMLVFFSVF---FLWWLNFNLLNLPSLFLYLDFYVPL 438
PRK12650 PRK12650
DUF4040 family protein;
1-85 2.23e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.57  E-value: 2.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNlKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILEMVCLSWINCLIFFLYFISTGLT 80
Cdd:PRK12650 341 FMLIGVVDHQ-AGTRDIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPGGNAGVVLLLVGAALG 419


                 ....*
gi 344190015  81 ACYSF 85
Cdd:PRK12650 420 AVFTF 424
PRK07390 PRK07390
NAD(P)H-quinone oxidoreductase subunit F; Validated
 1-81 2.52e-03

NAD(P)H-quinone oxidoreductase subunit F; Validated


Pssm-ID: 236008 [Multi-domain]  Cd Length: 613  Bit Score: 38.35  E-value: 2.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNlKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSkdlILEMVCLSWINCLIFFLYFIST-GL 79
Cdd:PRK07390 350 FMSVGSIILT-TITQDLTELGGLWSRMPATTLAFLVGSAGLVALLPLGGFWA---LLRLADGLWAVSPWLVGVLLLVnAL 425


                 ..
gi 344190015  80 TA 81
Cdd:PRK07390 426 TA 427
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 1-58 2.65e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 38.17  E-value: 2.65e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 344190015   1 FMCAGSMIHNLKDsQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILE 58
Cdd:PRK08667 350 FLTAGSVVHATGT-RNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYE 406
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-90 5.05e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 37.17  E-value: 5.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNLKdSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSK-DLILEMVCLSWINCLIFFLyfISTGL 79
Cdd:PRK08375 340 FLAAGAIEVTYG-TRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKwYLVVGAVEAGQWLVLAVLL--ASSLL 416

                         90
                 ....*....|.
gi 344190015  80 TACYSFRLFYY 90
Cdd:PRK08375 417 ALLYFLRIWYR 427
PRK12646 PRK12646
DUF4040 family protein;
1-58 5.44e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 37.43  E-value: 5.44e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 344190015   1 FMCAGSMIHNlKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILE 58
Cdd:PRK12646 357 FMGVGIIDHE-AGTRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLD 413
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-58 5.70e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 37.21  E-value: 5.70e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 344190015   1 FMCAGSMIHNlKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDLILE 58
Cdd:PRK12647 328 FMVAGIIDHE-TGTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYE 384
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-86 6.36e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 37.09  E-value: 6.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 344190015   1 FMCAGSMIHNlKDSQDIRFMGSIVNFMPLTSVCLNVSSLSLCGIPFLAGFYSKDL----ILEMVCLSWINCLIFFLYFIS 76
Cdd:PRK12648 340 FMAAGIIDHE-TGTRDMRRLSGLRRLMPITATLAMVAAAAMAGVPLLNGFLSKEMffaeTLDTHLLGSLDWLLPVAATLA 418

                         90
                 ....*....|
gi 344190015  77 TGLTACYSFR 86
Cdd:PRK12648 419 GAFSVAYSLR 428
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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