NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|34397715|gb|AAQ66776|]
View 

grpE protein [Porphyromonas gingivalis W83]

Protein Classification

nucleotide exchange factor GrpE( domain architecture ID 10001738)

nucleotide exchange factor GrpE functions as a nucleotide exchange factor for DnaK and participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may also function as a thermosensor

CATH:  3.90.20.20|2.30.22.10
Gene Ontology:  GO:0000774|GO:0051087|GO:0042803|GO:0006457
SCOP:  4003783|4002724

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 49-194 4.39e-56

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 174.19  E-value: 4.39e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  49 EQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSK 128
Cdd:COG0576   2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEEDEDVKSLLEGVEMTLKQ 81

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 34397715 129 FMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:COG0576  82 LLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVE-PGTVVEVLQKGYRLGDRVLRPAMVVVAK 146
 
Name Accession Description Interval E-value
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 49-194 4.39e-56

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 174.19  E-value: 4.39e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  49 EQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSK 128
Cdd:COG0576   2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEEDEDVKSLLEGVEMTLKQ 81

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 34397715 129 FMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:COG0576  82 LLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVE-PGTVVEVLQKGYRLGDRVLRPAMVVVAK 146
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 56-192 9.90e-52

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 162.68  E-value: 9.90e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  56 AALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQK 135
Cdd:cd00446   1 KELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKEEELKNLLEGVEMTLKQLLKVLEK 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 34397715 136 QGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:cd00446  81 HGVEEIEPEGEKFDPNLHEAVMQVESPDKE-PGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
29-194 8.01e-45

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 146.21  E-value: 8.01e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    29 ENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSN 108
Cdd:pfam01025   1 EEKKNEEALTDEIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   109 LGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHA 188
Cdd:pfam01025  81 APENEDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKP-EGTVVEVLQKGYKLHDRVLRPA 159


                  ....*.
gi 34397715   189 HVVVGE 194
Cdd:pfam01025 160 MVVVSK 165
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 4-194 1.36e-32

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 115.48  E-value: 1.36e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    4 QKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADpVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSEL 83
Cdd:PRK14140   3 EKNEQVEEEVEETEVEEAVEDEVEEETVEEESEAELLDEEQAK-IAELEAKLDELEERYLRLQADFENYKRRIQKENEAA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   84 IRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPS 163
Cdd:PRK14140  82 EKYRAQSLASDLLPALDNFERALQIEADDEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVMQDEDED 161

                        170       180       190
                 ....*....|....*....|....*....|.
gi 34397715  164 AEQkGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14140 162 FES-NEVVEELQKGYKLKDRVIRPSMVKVNQ 191
 
Name Accession Description Interval E-value
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 49-194 4.39e-56

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 174.19  E-value: 4.39e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  49 EQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSK 128
Cdd:COG0576   2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEEDEDVKSLLEGVEMTLKQ 81

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 34397715 129 FMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:COG0576  82 LLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVE-PGTVVEVLQKGYRLGDRVLRPAMVVVAK 146
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 56-192 9.90e-52

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 162.68  E-value: 9.90e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  56 AALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQK 135
Cdd:cd00446   1 KELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKEEELKNLLEGVEMTLKQLLKVLEK 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 34397715 136 QGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:cd00446  81 HGVEEIEPEGEKFDPNLHEAVMQVESPDKE-PGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
29-194 8.01e-45

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 146.21  E-value: 8.01e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    29 ENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSN 108
Cdd:pfam01025   1 EEKKNEEALTDEIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   109 LGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLNDKVIRHA 188
Cdd:pfam01025  81 APENEDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKP-EGTVVEVLQKGYKLHDRVLRPA 159


                  ....*.
gi 34397715   189 HVVVGE 194
Cdd:pfam01025 160 MVVVSK 165
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 4-194 1.36e-32

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 115.48  E-value: 1.36e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    4 QKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADpVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSEL 83
Cdd:PRK14140   3 EKNEQVEEEVEETEVEEAVEDEVEEETVEEESEAELLDEEQAK-IAELEAKLDELEERYLRLQADFENYKRRIQKENEAA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   84 IRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPS 163
Cdd:PRK14140  82 EKYRAQSLASDLLPALDNFERALQIEADDEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVMQDEDED 161

                        170       180       190
                 ....*....|....*....|....*....|.
gi 34397715  164 AEQkGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14140 162 FES-NEVVEELQKGYKLKDRVIRPSMVKVNQ 191
PRK14145 PRK14145
heat shock protein GrpE; Provisional
 2-194 1.54e-31

heat shock protein GrpE; Provisional


Pssm-ID: 184536 [Multi-domain]  Cd Length: 196  Bit Score: 113.09  E-value: 1.54e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    2 NKQKNNRERTPQPEQDTERDEQLTNSHENdidsaPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKS 81
Cdd:PRK14145  13 EKDVNNLSSNEQMEGPPEDEQAQQNQPQQ-----QTVDEIEELKQKLQQKEVEAQEYLDIAQRLKAEFENYRKRTEKEKS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   82 ELIRNGGEKVLVDLLPVIDDFERALSNLGDMsepAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVaMIPA 161
Cdd:PRK14145  88 EMVEYGKEQVILELLPVMDNFERALASSGDY---NSLKEGIELIYRQFKKILDKFGVKEIEAEGQIFDPYKHHAV-MQEE 163

                        170       180       190
                 ....*....|....*....|....*....|...
gi 34397715  162 PSAEQKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14145 164 VEGKQPNEIIEVFQKGYYLKDKVIRPSLVKVAK 196
PRK14153 PRK14153
heat shock protein GrpE; Provisional
 2-192 8.37e-31

heat shock protein GrpE; Provisional


Pssm-ID: 184540 [Multi-domain]  Cd Length: 194  Bit Score: 111.09  E-value: 8.37e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    2 NKQKNNRERTPQPEQDTERDEQLTNSHENdidsAPAAEEndkvadpVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKS 81
Cdd:PRK14153   7 GKDKAENSEARNSGSSAEEAEELKEEPED----STADSE-------TEKCREEIESLKEQLFRLAAEFDNFRKRTAREME 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   82 ELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPA 161
Cdd:PRK14153  76 ENRKFVLEQVLLDLLEVTDNFERALESARTAEDMNSIVEGIEMVSKQFFSILEKYGLERIECEGEEFDPHRHEAMMHVET 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 34397715  162 pSAEQKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14153 156 -SEVPDNTIVDVCKPGYALNSKVIRPAMVSV 185
PRK14144 PRK14144
heat shock protein GrpE; Provisional
 2-192 1.74e-27

heat shock protein GrpE; Provisional


Pssm-ID: 184535 [Multi-domain]  Cd Length: 199  Bit Score: 102.88  E-value: 1.74e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    2 NKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLT--AQLAALN-DTHLRLMAEYDNYRKRTLK 78
Cdd:PRK14144   5 NKKDWKKFKDEHKEEHKVENEILEEETDEESQHQEPALGHPSYTALEEQLTlaEQKAHENwEKSVRALAELENVRRRMER 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   79 EKSELIRNGGEKVLVDLLPVIDDFERALsNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAM 158
Cdd:PRK14144  85 EVANAHKYGVEKLISALLPVVDSLEQAL-QLADKNSDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSM 163

                        170       180       190
                 ....*....|....*....|....*....|....
gi 34397715  159 IPAPSAEqKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14144 164 QPAPGAP-PNSVITVFQKGYKLSDRVIRPARVIV 196
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 2-192 1.21e-26

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 101.34  E-value: 1.21e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    2 NKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLTAQLAAL-------NDTHLRLMAEYDNYRK 74
Cdd:PRK14143  23 NSPESSEEVTEQEAELTNPEGDAAEAESSPDSGSAASETAADNAARLAQLEQELESLkqeleelNSQYMRIAADFDNFRK 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   75 RTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPA-AIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLC 153
Cdd:PRK14143 103 RTSREQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAqALHRSYQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLH 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 34397715  154 DAVAMipAPSAEQ-KGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14143 183 EAVLR--EPSDEHpEDVVLEELQRGYHLGGRVLRHAMVKV 220
PRK14162 PRK14162
heat shock protein GrpE; Provisional
 1-194 1.66e-26

heat shock protein GrpE; Provisional


Pssm-ID: 237631 [Multi-domain]  Cd Length: 194  Bit Score: 99.91  E-value: 1.66e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    1 MNKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEK 80
Cdd:PRK14162   1 MSKEEFPSEKDLPQEETTDEAPKKEAKEAPKEEDQEKQNPVEDLEKEIADLKAKNKDLEDKYLRSQAEIQNMQNRYAKER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   81 SELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIP 160
Cdd:PRK14162  81 AQLIKYESQSLAKDVLPAMDNLERALAVKADDEAAKQLKKGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAVQTVA 160

                        170       180       190
                 ....*....|....*....|....*....|....
gi 34397715  161 APSAEQKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14162 161 AENDDQKDHVVQVLQKGYQYKDRTLRPAMVVVAQ 194
PRK14151 PRK14151
heat shock protein GrpE; Provisional
 18-192 4.26e-26

heat shock protein GrpE; Provisional


Pssm-ID: 172640 [Multi-domain]  Cd Length: 176  Bit Score: 98.31  E-value: 4.26e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   18 TERDEQLTNSHENDIDSAPAAEENdkvADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLP 97
Cdd:PRK14151   2 ADEQTLDLQAPEAAQAEAAAGDDL---TARVQELEEQLAAAKDQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLLP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   98 VIDDFERALsnlgDMSEPA-----AIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVID 172
Cdd:PRK14151  79 VVDSLERGL----ELSSADdeaikPMREGVELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVE-PNSVLK 153

                        170       180
                 ....*....|....*....|
gi 34397715  173 CVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14151 154 VFQKGYLLNGRLLRPAMVVV 173
PRK14160 PRK14160
heat shock protein GrpE; Provisional
 2-192 6.58e-26

heat shock protein GrpE; Provisional


Pssm-ID: 237629 [Multi-domain]  Cd Length: 211  Bit Score: 99.06  E-value: 6.58e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    2 NKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPA-AEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEK 80
Cdd:PRK14160  23 NKEEDKGKEEDLEFEEIEKEEIIEDSEESNEVKIEElKDENNKLKEENKKLENELEALKDRLLRTVAEYDNYRKRTAKEK 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   81 SELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEpaaIKEGVELIYSKFMDYLQKQGVKKIETADlPFDADLCDAVAMIP 160
Cdd:PRK14160 103 EGIYSDACEDVLKELLPVLDNLERAAAVEGSVED---LKKGIEMTVKQFKTSLEKLGVEEISTEG-EFDPNLHNAVMHVE 178

                        170       180       190
                 ....*....|....*....|....*....|..
gi 34397715  161 APSAEqKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14160 179 DENYG-ENEIVEVFQKGYKRGDKVIRYSMVKV 209
PRK14148 PRK14148
heat shock protein GrpE; Provisional
 3-192 1.07e-24

heat shock protein GrpE; Provisional


Pssm-ID: 172637 [Multi-domain]  Cd Length: 195  Bit Score: 95.20  E-value: 1.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    3 KQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSE 82
Cdd:PRK14148   4 QEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   83 LIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAP 162
Cdd:PRK14148  84 ARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNP 163

                        170       180       190
                 ....*....|....*....|....*....|
gi 34397715  163 SAEQKgKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14148 164 EFEDN-TIFDVFQKGYMLNGRIVRAAKVVI 192
PRK14158 PRK14158
heat shock protein GrpE; Provisional
 1-192 4.94e-24

heat shock protein GrpE; Provisional


Pssm-ID: 172646 [Multi-domain]  Cd Length: 194  Bit Score: 93.46  E-value: 4.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    1 MNKQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEenDKVADPVEQLTA---QLAALNDTHLRLMAEYDNYRKRTL 77
Cdd:PRK14158   1 MDKKKHGSHQIAEALKAKAAKEAEAAQGKPEAAQPVAAA--DRIKELEEALAAkeaEAAANWDKYLRERADLENYRKRVQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   78 KEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSePAAIKEGVELIYSKFMDYLQKQGVKKIETAD-LPFDADLCDav 156
Cdd:PRK14158  79 KEKEELLKYGNESLILEILPAVDNMERALDHADEES-MSAIIEGIRMTLSMLLSTLKKFGVTPVEAEKgTPFDPAYHQ-- 155

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 34397715  157 AMIPAPSAEQK-GKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14158 156 AMCQVESAEQEpNTVVAVFQKGYLLNERLLRPAMVSV 192
PRK14150 PRK14150
heat shock protein GrpE; Provisional
 7-192 1.13e-23

heat shock protein GrpE; Provisional


Pssm-ID: 184539 [Multi-domain]  Cd Length: 193  Bit Score: 92.67  E-value: 1.13e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    7 NRERTPQPEQDTERDEQlTNSHENDIDSAPAAEENDKVADPVEQLTAQLAALN----DTHLRLMAEYDNYRKRTLKEKSE 82
Cdd:PRK14150   3 NEEQKTPQEQVSEEIEA-EVEQQEEADEAELEDELDEADARIAELEAQLAEAQaeerDSVLRARAEVENIRRRAEQDVEK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   83 LIRNGGEKVLVDLLPVIDDFERALsNLGDMSEPA--AIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIP 160
Cdd:PRK14150  82 AHKFALEKFANELLPVIDNLERAL-QAADKENEAlkALIEGVELTLKSLLDTVAKFGVEVVGPVGEPFNPEVHQAISMQE 160

                        170       180       190
                 ....*....|....*....|....*....|..
gi 34397715  161 APSAEQKgKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14150 161 SEDHEPN-TVMMVMQKGYTLNGRLLRPAMVMV 191
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 9-194 4.66e-23

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 91.27  E-value: 4.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    9 ERTPQPEQDterDEQLTNSHEN--DIDSAPAAEENDKVADPVEQLTAQLAALN----DTHLRLMAEYDNYRKRTLKEKSE 82
Cdd:PRK10325   6 QKTPEGQAP---EEIIMDQHEEieAVEPEASAEQVDPRDEKIANLEAQLAEAQtrerDGILRVKAEMENLRRRTELDIEK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   83 LIRNGGEKVLVDLLPVIDDFERALSnLGDMSEP--AAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIP 160
Cdd:PRK10325  83 AHKFALEKFINELLPVIDSLDRALE-VADKANPdmSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVE 161

                        170       180       190
                 ....*....|....*....|....*....|....
gi 34397715  161 APSAEqKGKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK10325 162 SDDVA-PGNVLGIMQKGYTLNGRTIRAAMVTVAK 194
PRK14147 PRK14147
heat shock protein GrpE; Provisional
 26-192 5.17e-22

heat shock protein GrpE; Provisional


Pssm-ID: 237625 [Multi-domain]  Cd Length: 172  Bit Score: 87.70  E-value: 5.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   26 NSHENDIDSAPAAE---ENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDF 102
Cdd:PRK14147   2 NQDHPEFDSEDLAQnppETDPLKAEVESLRSEIALVKADALRERADLENQRKRIARDVEQARKFANEKLLGELLPVFDSL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  103 ERALSNLGdmSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTLND 182
Cdd:PRK14147  82 DAGLTAAG--TEPSPLRDGLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVA-PGHVVQVFQKGYLLNE 158

                        170
                 ....*....|
gi 34397715  183 KVIRHAHVVV 192
Cdd:PRK14147 159 RLLRPALVVV 168
PRK14149 PRK14149
heat shock protein GrpE; Provisional
 3-192 5.52e-21

heat shock protein GrpE; Provisional


Pssm-ID: 184538 [Multi-domain]  Cd Length: 191  Bit Score: 85.69  E-value: 5.52e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    3 KQKNNRERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDkvADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSE 82
Cdd:PRK14149   2 KDEHNQEHDHLSQKEPESEEKACACKEQQGEEKQEASEKE--GEIKEDFELKYKEMHEKYLRVHADFENVKKRLERDKSM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   83 LIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETaDLPFDADLCDAVAMIPAP 162
Cdd:PRK14149  80 ALEYAYEKIALDLLPVIDALLGALKSAAEVDKESALTKGLELTMEKLHEVLARHGIEGIEC-LEEFDPNFHNAIMQVKSE 158

                        170       180       190
                 ....*....|....*....|....*....|
gi 34397715  163 SAEQkGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14149 159 EKEN-GKIVQVLQQGYKYKGRVLRPAMVSI 187
PRK14141 PRK14141
heat shock protein GrpE; Provisional
 31-192 3.72e-19

heat shock protein GrpE; Provisional


Pssm-ID: 172630  Cd Length: 209  Bit Score: 81.25  E-value: 3.72e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   31 DIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERAL---- 106
Cdd:PRK14141  23 DREAKPYEMEDDPEPDPLEALKAENAELKDRMLRLAAEMENLRKRTQRDVADARAYGIAGFARDMLSVSDNLRRALdaip 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  107 SNLGDMSEPA--AIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEQkGKVIDCVKTGYTLNDKV 184
Cdd:PRK14141 103 AEARAAADAGlkALIEGVEMTERAMLNALERHGVKKLDPEGQKFDPNFHQAMFEVPNPDVPN-NTVVQVVQAGYTIGERV 181


                 ....*...
gi 34397715  185 IRHAHVVV 192
Cdd:PRK14141 182 LRPAMVGV 189
PRK14139 PRK14139
heat shock protein GrpE; Provisional
 7-192 5.78e-18

heat shock protein GrpE; Provisional


Pssm-ID: 237621 [Multi-domain]  Cd Length: 185  Bit Score: 77.32  E-value: 5.78e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    7 NRERTPQPEQDTERDEqltnshendiDSAPAAEENDKVADPVEQLTAQLAALN-------DTHLRLMAEYDNYRKRTLKE 79
Cdd:PRK14139   3 NTQQNPSEQEAEEAGA----------AAQAAAAAAAAAEDAAPALEAELAEAEakaaelqDSFLRAKAETENVRRRAQED 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   80 KSELIRNGGEKVLVDLLPVIDDFERALSNlgDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMI 159
Cdd:PRK14139  73 VAKAHKFAIESFAESLLPVKDSLEAALAD--ESGDLEKLREGVELTLKQLTSAFEKGRVVEINPVGEKFDPHQHQAISMV 150

                        170       180       190
                 ....*....|....*....|....*....|....
gi 34397715  160 PApsaEQK-GKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14139 151 PA---EQEpNTVVAVLQKGYTIADRVLRPALVTV 181
PRK14159 PRK14159
heat shock protein GrpE; Provisional
 15-194 3.05e-17

heat shock protein GrpE; Provisional


Pssm-ID: 172647 [Multi-domain]  Cd Length: 176  Bit Score: 75.50  E-value: 3.05e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   15 EQDTERDEQLTNSHENDIDSAPAAEENDKVadpvEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVD 94
Cdd:PRK14159   3 EQKQEFENENAENSEHLQDENLQNIEDVEQ----NKLQKDYDELKDKYMRANAEFENIKKRMEKEKLSAMAYANESFAKD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   95 LLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIEtADLPFDADLCDAVAMIPAPSaEQKGKVIDCV 174
Cdd:PRK14159  79 LLDVLDALEAAVNVECHDEISLKIKEGVQNTLDLFLKKLEKHGVALIK-EEKEFDPNLHEAMFHVDSEN-HQSGEVVQVL 156

                        170       180
                 ....*....|....*....|
gi 34397715  175 KTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14159 157 QKGYKIADRVIRPTKVSVAK 176
PRK14154 PRK14154
heat shock protein GrpE; Provisional
 3-193 7.53e-16

heat shock protein GrpE; Provisional


Pssm-ID: 237626 [Multi-domain]  Cd Length: 208  Bit Score: 72.54  E-value: 7.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    3 KQKNNRERTPQPEQDTERD----EQLTNSHENDIDsAPAAEendKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLK 78
Cdd:PRK14154  16 KAKNKWEKVMEAEEEQEEGggdgSQEMEPHREGLE-FPSRE---KLEGQLTRMERKVDEYKTQYLRAQAEMDNLRKRIER 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   79 EKSELIRNGGEKVLVDLLPVIDDFERAL-SNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIE-TADLPFDADLCDAV 156
Cdd:PRK14154  92 EKADIIKFGSKQLITDLLPVADSLIHGLeSPASEDPQVKSMRDGMSLTLDLLHNTLAKHGVQVINpNPGDPFDPALHEAM 171

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 34397715  157 AMIPAPSAeQKGKVIDCVKTGYTLNDKVIRHAHVVVG 193
Cdd:PRK14154 172 SVQAVPDA-KPDTIIQVLQKGYQLNGRVLRAARVIVA 207
PRK14164 PRK14164
heat shock protein GrpE; Provisional
 9-194 1.09e-14

heat shock protein GrpE; Provisional


Pssm-ID: 237632 [Multi-domain]  Cd Length: 218  Bit Score: 69.44  E-value: 1.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    9 ERTPQPEQDTERDEQLTNSHENDIDSAPAAEENDKVADPVEqltAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGG 88
Cdd:PRK14164  43 DDPFGDAVEGEIDPDLEADLEDLLDDVDPELADDGEASTVE---AQLAERTEDLQRVTAEYANYRRRTERERQAIIETAK 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   89 EKVLVDLLPVIDDFERALSNlGDMSEPAaikegVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEQKG 168
Cdd:PRK14164 120 AGVATDLLPILDDLDLAEQH-GDLNEGP-----LKAFSDKLTNVLAGLKVEKFGEEGDAFDPEIHEAVQDLSSGDEKVLG 193

                        170       180
                 ....*....|....*....|....*.
gi 34397715  169 KVIdcvKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14164 194 TVL---RKGYRMGDRVLRTAMVIIAD 216
PRK14155 PRK14155
heat shock protein GrpE; Provisional
 38-192 4.36e-14

heat shock protein GrpE; Provisional


Pssm-ID: 237627 [Multi-domain]  Cd Length: 208  Bit Score: 67.68  E-value: 4.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   38 AEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAA 117
Cdd:PRK14155  12 PFEADDAAQEIEALKAEVAALKDQALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRATAASPKDSADPA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  118 IKE---GVELIYSKFMDYLQKQGVKKIETAD-LPFDADLCDavAMIPAPSAE-QKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14155  92 VKNfiiGVEMTEKELLGAFERNGLKKIDPAKgDKFDPHLHQ--AMMEQPSTEvAAGGVLQVMQAGYELMGRLVRPAMVAV 169
PRK14146 PRK14146
heat shock protein GrpE; Provisional
 16-194 1.19e-13

heat shock protein GrpE; Provisional


Pssm-ID: 172635 [Multi-domain]  Cd Length: 215  Bit Score: 66.68  E-value: 1.19e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   16 QDTERDEQLTNSHENDIDSAPAAEENDKVADPVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDL 95
Cdd:PRK14146  31 ENMNSEESQTITEETQEQAVEGAETETSLQKELDNAKKEIESLKDSWARERAEFQNFKRRSAQEFVSIRKEAVKSLVSGF 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   96 LPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEQKgKVIDCVK 175
Cdd:PRK14146 111 LNPIDNLERVGATQNQSEELKPFVEGVKMILKEFYSVLEKSNVIRFDPKGEPFDPMSMEALSSEEGDQYSEE-TVIDVYQ 189

                        170       180
                 ....*....|....*....|...
gi 34397715  176 TGYTLND----KVIRHAHVVVGE 194
Cdd:PRK14146 190 AGYYYKEnedkFTLRPARVRIGK 212
PRK14163 PRK14163
heat shock protein GrpE; Provisional
 9-194 4.63e-12

heat shock protein GrpE; Provisional


Pssm-ID: 184546 [Multi-domain]  Cd Length: 214  Bit Score: 62.07  E-value: 4.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715    9 ERTPQPEqdtERDEQLTNSHENDIDSAPAAEENDKVA---DPVEQLTAQL----AALNDTHL---RLMAEYDNYRKRTLK 78
Cdd:PRK14163   3 EETPGFE---EKPDVPSGATPDDAEPKAASEEGAAPAgdaAATAGLTAQLdqvrTALGERTAdlqRLQAEYQNYRRRVER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   79 EKSELIRNGGEKVLVDLLPVIDDFERALSNLGDMSEPAAIKEGVELIYSKFmdylqkqGVKKIETADLPFDADLCDAVAM 158
Cdd:PRK14163  80 DRVTVKEIAVANLLSELLPVLDDVGRAREHGELVGGFKSVAESLETTVAKL-------GLQQFGKEGEPFDPTIHEALMH 152

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 34397715  159 IPAPSAEQKgKVIDCVKTGYTLNDKVIRHAHVVVGE 194
Cdd:PRK14163 153 SYAPDVTET-TCVAILQPGYRIGERTIRPARVAVAE 187
PRK14157 PRK14157
heat shock protein GrpE; Provisional
 25-192 6.99e-12

heat shock protein GrpE; Provisional


Pssm-ID: 184543 [Multi-domain]  Cd Length: 227  Bit Score: 61.90  E-value: 6.99e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   25 TNSHENDIDSAPAAEENDKVAD----PVEQLTAQLAALNDTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLPVID 100
Cdd:PRK14157  59 AAAEGEAKAAAEKTGEAQSDSDdtltPLGQAKKEAAEYLEALQRERAEFINYRNRTQKEQDRFRQHGIIDVLTALLPALD 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715  101 DFERalsnlgdMSEPAAIKEGVELIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPAPSAEqKGKVIDCVKTGYTL 180
Cdd:PRK14157 139 DIDR-------IREHSEMDDSFKAVAAKIDKAFEKFGVEKFGEKGEDFDPTKHDAILHKPDPDAE-KETVDTVVEAGYRI 210

                        170
                 ....*....|..
gi 34397715  181 NDKVIRHAHVVV 192
Cdd:PRK14157 211 GDRVIRAARVVV 222
PRK14142 PRK14142
heat shock protein GrpE; Provisional
 14-192 1.95e-10

heat shock protein GrpE; Provisional


Pssm-ID: 237623  Cd Length: 223  Bit Score: 57.70  E-value: 1.95e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   14 PEQDTERDEQLTNSHENDIDSAP------------AAEENDKVAdpveQLTAQLAalndthlRLMAEYDNYRKRTLKEKS 81
Cdd:PRK14142   7 GEQVTVTDKRRIDPETGEVRHVPpgdmpggtaaadAAHTEDKVA----ELTADLQ-------RVQADFANYRKRALRDQQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   82 ELIRNGGEKVLVDLLPVIDDFERALSNlGDMsEPAAIKEgvelIYSKFMDYLQKQGVKKIETADLPFDADLCDAVAMIPA 161
Cdd:PRK14142  76 AAADRAKASVVSQLLGVLDDLERARKH-GDL-ESGPLKS----VADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGD 149

                        170       180       190
                 ....*....|....*....|....*....|.
gi 34397715  162 PSAEQKGKVIDCVKTGYTLNDKVIRHAHVVV 192
Cdd:PRK14142 150 GGQGSKPVIGTVMRQGYQLGEQVLRHALVGV 180
PRK14156 PRK14156
heat shock protein GrpE; Provisional
 28-192 9.65e-09

heat shock protein GrpE; Provisional


Pssm-ID: 237628 [Multi-domain]  Cd Length: 177  Bit Score: 52.53  E-value: 9.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   28 HENDIDSAPAAEENDKVADPVEQLTAQLAALN----------DTHLRLMAEYDNYRKRTLKEKSELIRNGGEKVLVDLLP 97
Cdd:PRK14156   6 KNEEVEEEVEATETEETVEEVVEETPEKSELElaneradefeNKYLRAHAEMQNIQRRANEERQQLQRYRSQDLAKAILP 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34397715   98 VIDDFERALSNLGDMSEpaaIKEGVELIYSKFMDYLQKQGVKKIETADlpFDADLCDAVAMIPAPSAEQKGKVIDCVKTG 177
Cdd:PRK14156  86 SLDNLERALAVEGLTDD---VKKGLEMVQESLIQALKEEGVEEVAVDS--FDHNLHMAVQTLPADDEHPADSIAQVFQKG 160

                        170
                 ....*....|....*
gi 34397715  178 YTLNDKVIRHAHVVV 192
Cdd:PRK14156 161 YKLHERLLRPAMVVV 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH