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Conserved domains on  [gi|334898|gb|AAB06287|]
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fusion protein [Respirovirus muris]

Protein Classification

fusion glycoprotein F0( domain architecture ID 10455199)

fusion glycoprotein F0 is a class I viral fusion protein that directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
28-497 0e+00

Fusion glycoprotein F0;


:

Pssm-ID: 395418  Cd Length: 473  Bit Score: 620.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898      28 PRDRLSNIGVIVDEGKSLKIAGSHESRYIVLSLVPVVDFENGCGTAQVIQYKSLLNRLLIPLRDALDLQEALITVtsDTT 107
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTNKCTKTEVDQYKNTLTTLLTPIADALNRIEAPITV--LTS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     108 QNAGAPQPKFFGAVIGTIALGVATSAQITAGIALAEAREAKRDIALIKESMTKTHKSIELLQNAVGEQILALKTLQDFVN 187
Cdd:pfam00523  79 TISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFIN 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     188 DEIKPAISELGCETAALRLGIKLTQHYSELLTAFGSNFGTIGEKSLTLQALSSLYSANITEIMTTIRTGQSNIYDVIYTE 267
Cdd:pfam00523 159 TQLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSR 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     268 QIKGTVIDVDLKRYMVTLSVKIPILSEVPGVLIHKASSISYNIDGEEWYVTVPSHILSRASFLGGADITDCVESRLTYIC 347
Cdd:pfam00523 239 SIKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVIC 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     348 PRDPAQLIPDSQQKCILGDTTRCPVTKVVDSLIPKFAFVNGGVVANCIASTCTCGTGRRPISQDRSKGVVFLTHDNCGLI 427
Cdd:pfam00523 319 DQDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTV 398

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     428 GVNGVELYANRRGHDATWGVQNLTVGPAIAIRPVDISLNLADATNFLQDSKAELEKARKILSEVGRWYNS 497
Cdd:pfam00523 399 SVDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILS 468
 
Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
28-497 0e+00

Fusion glycoprotein F0;


Pssm-ID: 395418  Cd Length: 473  Bit Score: 620.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898      28 PRDRLSNIGVIVDEGKSLKIAGSHESRYIVLSLVPVVDFENGCGTAQVIQYKSLLNRLLIPLRDALDLQEALITVtsDTT 107
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTNKCTKTEVDQYKNTLTTLLTPIADALNRIEAPITV--LTS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     108 QNAGAPQPKFFGAVIGTIALGVATSAQITAGIALAEAREAKRDIALIKESMTKTHKSIELLQNAVGEQILALKTLQDFVN 187
Cdd:pfam00523  79 TISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFIN 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     188 DEIKPAISELGCETAALRLGIKLTQHYSELLTAFGSNFGTIGEKSLTLQALSSLYSANITEIMTTIRTGQSNIYDVIYTE 267
Cdd:pfam00523 159 TQLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSR 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     268 QIKGTVIDVDLKRYMVTLSVKIPILSEVPGVLIHKASSISYNIDGEEWYVTVPSHILSRASFLGGADITDCVESRLTYIC 347
Cdd:pfam00523 239 SIKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVIC 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     348 PRDPAQLIPDSQQKCILGDTTRCPVTKVVDSLIPKFAFVNGGVVANCIASTCTCGTGRRPISQDRSKGVVFLTHDNCGLI 427
Cdd:pfam00523 319 DQDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTV 398

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     428 GVNGVELYANRRGHDATWGVQNLTVGPAIAIRPVDISLNLADATNFLQDSKAELEKARKILSEVGRWYNS 497
Cdd:pfam00523 399 SVDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILS 468
 
Name Accession Description Interval E-value
Fusion_gly pfam00523
Fusion glycoprotein F0;
28-497 0e+00

Fusion glycoprotein F0;


Pssm-ID: 395418  Cd Length: 473  Bit Score: 620.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898      28 PRDRLSNIGVIVDEGKSLKIAGSHESRYIVLSLVPVVDFENGCGTAQVIQYKSLLNRLLIPLRDALDLQEALITVtsDTT 107
Cdd:pfam00523   1 DEDNLSKIGVVVTGGKFLKIRTSSSTSYIVIKLLPNIGNTNKCTKTEVDQYKNTLTTLLTPIADALNRIEAPITV--LTS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     108 QNAGAPQPKFFGAVIGTIALGVATSAQITAGIALAEAREAKRDIALIKESMTKTHKSIELLQNAVGEQILALKTLQDFVN 187
Cdd:pfam00523  79 TISSKRKKRFAGAVIGGIALGVATAAQITAGIALAQALENAGAIAKIKNSIQATNEAVVKLQNGVSVLATAVNALQDFIN 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     188 DEIKPAISELGCETAALRLGIKLTQHYSELLTAFGSNFGTIGEKSLTLQALSSLYSANITEIMTTIRTGQSNIYDVIYTE 267
Cdd:pfam00523 159 TQLNPAINQLSCDIADLKLGISLTQYLSELLTVFGPNLGNPVENPLSIQALSSLLGGNLNALVTKLGYTNSDILDLLSSR 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     268 QIKGTVIDVDLKRYMVTLSVKIPILSEVPGVLIHKASSISYNIDGEEWYVTVPSHILSRASFLGGADITDCVESRLTYIC 347
Cdd:pfam00523 239 SIKGQIILVDLEEYMIVLSVQLPILGEIDNTLVKELSSISYNIDGQEWYTQVPKVVLNRGSLISGPDASDCKVTSLHVIC 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     348 PRDPAQLIPDSQQKCILGDTTRCPVTKVVDSLIPKFAFVNGGVVANCIASTCTCGTGRRPISQDRSKGVVFLTHDNCGLI 427
Cdd:pfam00523 319 DQDPAFPMSPEVQECLSGNTYACPRSTVVGSISPRFATSLGAIVANCISTTCLCGTPGRPIIQPGSKGLTYISNDDCDTV 398

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334898     428 GVNGVELYANRRGHDATWGVQNLTVGPAIAIRPVDISLNLADATNFLQDSKAELEKARKILSEVGRWYNS 497
Cdd:pfam00523 399 SVDGIVIYLSKKFDNVTGNNLTIKLGPPINTPPLDISTELSKVNESLQQSKDLLEESNKILDSVNVKILS 468
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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