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Conserved domains on  [gi|334187956|ref|NP_001190403|]
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D111/G-patch domain-containing protein [Arabidopsis thaliana]

Protein Classification

G_patch and zf-C2H2_jaz domain-containing protein( domain architecture ID 10648307)

G_patch and zf-C2H2_jaz domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 64-108 1.41e-17

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


:

Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 74.89  E-value: 1.41e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 334187956    64 ISSSNVGFRLLQKMGWK-GKGLGKQEQGITEPIKSGIRDRRLGLGK 108
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKeGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 161-188 1.36e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.61  E-value: 1.36e-03
                          10        20
                  ....*....|....*....|....*...
gi 334187956  161 FYCELCSKQYRTVMEFEGHLSSydHNHK 188
Cdd:pfam12171   2 FYCVLCDKYFKSENALQNHLKS--KKHK 27
 
Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 64-108 1.41e-17

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 74.89  E-value: 1.41e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 334187956    64 ISSSNVGFRLLQKMGWK-GKGLGKQEQGITEPIKSGIRDRRLGLGK 108
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKeGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 66-107 1.14e-16

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 72.16  E-value: 1.14e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 334187956   66 SSNVGFRLLQKMGWK-GKGLGKQEQGITEPIKSGIRDRRLGLG 107
Cdd:pfam01585   1 TSNIGFKLLQKMGWKeGQGLGKNEQGIAEPIEAKIKKDRRGLG 43
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 161-188 1.36e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.61  E-value: 1.36e-03
                          10        20
                  ....*....|....*....|....*...
gi 334187956  161 FYCELCSKQYRTVMEFEGHLSSydHNHK 188
Cdd:pfam12171   2 FYCVLCDKYFKSENALQNHLKS--KKHK 27
 
Name Accession Description Interval E-value
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 64-108 1.41e-17

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 74.89  E-value: 1.41e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 334187956    64 ISSSNVGFRLLQKMGWK-GKGLGKQEQGITEPIKSGIRDRRLGLGK 108
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKeGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 66-107 1.14e-16

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 72.16  E-value: 1.14e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 334187956   66 SSNVGFRLLQKMGWK-GKGLGKQEQGITEPIKSGIRDRRLGLG 107
Cdd:pfam01585   1 TSNIGFKLLQKMGWKeGQGLGKNEQGIAEPIEAKIKKDRRGLG 43
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 161-188 1.36e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.61  E-value: 1.36e-03
                          10        20
                  ....*....|....*....|....*...
gi 334187956  161 FYCELCSKQYRTVMEFEGHLSSydHNHK 188
Cdd:pfam12171   2 FYCVLCDKYFKSENALQNHLKS--KKHK 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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