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Conserved domains on  [gi|333236219|ref|YP_004465048|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Barilius bendelisis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.07e-84

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 246.59  E-value: 1.07e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVAFWGGWYEGSWVVIDGLEGFSMVRGDTSGVAVMYSFGGEMLVVCAWALLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 333236219 161 LIRGLDCGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.07e-84

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 246.59  E-value: 1.07e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVAFWGGWYEGSWVVIDGLEGFSMVRGDTSGVAVMYSFGGEMLVVCAWALLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 333236219 161 LIRGLDCGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 5.72e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.74  E-value: 5.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   17 IAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTAL-AAESYPEAWGSRSVVGYVTAYI 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 333236219   96 LGVSLVAVAFWGGWYEGSWVVIDGLEGfsmvRGDTSGVAVMYSFGGeMLVVCAWALLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.07e-84

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 246.59  E-value: 1.07e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVAFWGGWYEGSWVVIDGLEGFSMVRGDTSGVAVMYSFGGEMLVVCAWALLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 333236219 161 LIRGLDCGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 2.95e-58

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 179.66  E-value: 2.95e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVaFWGGWYEGSWVVIDGLEGFSMVRGDTSGVAVMYSFGGEMLVVCAWALLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYI-LFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 333236219 161 LIRGLDCGALRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.78e-45

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 147.20  E-value: 1.78e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVAFWGGW-YEGSWVVIDGLEGFSMVRGDTSGVAVMYSFGGEMLVVCAWALLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 333236219 160 ELIRGLDCGALRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 2.48e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 123.76  E-value: 2.48e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVV--GYVTAYILGVSLVAVAFWGGWYE--------GSWVVIDGlEGFSMVRGDTSGVAVMYSFGGEMLVVCAWA 150
Cdd:MTH00109  82 TWVSNKVVlgALLLGLLMELLLVLYVLKDDEVEvvfnfnglGDWVIYDT-GGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....
gi 333236219 151 LLLTLFVVLELIRG 164
Cdd:MTH00109 161 LFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 6.40e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 109.69  E-value: 6.40e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   1 MALYSCVLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  81 AWGSRSVVGYVTAYILGVSLVAVAFWGGWYEGSWVVIDGLEGFSMvrgdtSGVAVMYSFGGEMLVVCAWALLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 333236219 161 LIRGLDCGALRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 7-172 5.04e-19

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 78.79  E-value: 5.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   7 VLLVALIVGLIAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTALAAESYPEAWGSRS 86
Cdd:MTH00045   5 LFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219  87 VVGYVTAYILGVsLVAVAFWGGWYEGSWVVIDGLegfsmvrgDTSGVAVMYSFGGEMLVVCAWALLLTLFVVLELIRGLD 166
Cdd:MTH00045  85 VLVLSLLLSLWV-FISFDNFLELSNNNWSLVSLS--------DLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHE 155


                 ....*.
gi 333236219 167 CGALRA 172
Cdd:MTH00045 156 YSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 5.72e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 51.74  E-value: 5.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333236219   17 IAVASNPSPYFGALGLVMVAGVGCGILVGCGGSFLSMVLLLIYLGGMLVVFAYSTAL-AAESYPEAWGSRSVVGYVTAYI 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 333236219   96 LGVSLVAVAFWGGWYEGSWVVIDGLEGfsmvRGDTSGVAVMYSFGGeMLVVCAWALLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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