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Conserved domains on  [gi|33243860|gb|AAQ01486|]
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ATPase subunit 6, partial (mitochondrion) [Tyrannus melancholicus]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009573)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-206 1.18e-89

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177181  Cd Length: 227  Bit Score: 262.45  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELA 206
 
Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-206 1.18e-89

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 262.45  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELA 206
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-186 7.14e-35

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 122.70  E-value: 7.14e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860     6 FDQFMSPS--LLGIPLILISLLFPTLLF---PSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:TIGR01131   2 FSQFDISPitLFSLTLLSLILLLSLLIFlisSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170       180
                  ....*....|....*....|....*.
gi 33243860   161 LTANLTAGHLLIQLISTASTVLLPIM 186
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLLFSLMSSA 187
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-190 7.87e-25

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 94.77  E-value: 7.87e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310  25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104

                        90       100
                ....*....|....*....|.
gi 33243860 170 LLIQLISTASTVLLPIMPAVS 190
Cdd:cd00310 105 LLLALLSGLVPSLLSSVGLLP 125
ATP-synt_A pfam00119
ATP synthase A chain;
90-190 2.17e-18

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 79.46  E-value: 2.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIA-LGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160

                          90       100
                  ....*....|....*....|..
gi 33243860   169 HLLIQLISTASTVLLPIMPAVS 190
Cdd:pfam00119 161 HLLLLLLAGLIFALLSAGFLLG 182
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-189 7.94e-11

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 58.93  E-value: 7.94e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIA-LGHLLPEGTPtPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:COG0356  78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156

                        90       100
                ....*....|....*....|.
gi 33243860 169 HLLIQLISTASTVLLPIMPAV 189
Cdd:COG0356 157 HIILLLLAGLAPFLLLGVLSL 177
 
Name Accession Description Interval E-value
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-206 1.18e-89

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 262.45  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELA 206
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-206 6.94e-89

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 260.58  E-value: 6.94e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVA 206
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-206 5.93e-88

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 258.36  E-value: 5.93e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00073 161 LTANLTAGHLLIQLISTATLVLLPLMPTVSILTMIVLFLLTLLEIA 206
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-206 1.67e-69

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 211.35  E-value: 1.67e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00179 161 LTANITAGHLLMHLISSAVFVLMNFMGMVALLTLLVLFLLTLLEVA 206
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-206 3.44e-63

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 195.17  E-value: 3.44e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTLLFPSPdNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTP-NRLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 33243860  161 LTANLTAGHLLIQLISTASTVLLPIMPAVSLLTTIILLLLTI*EVA 206
Cdd:MTH00101 160 LTANITAGHLLIHLIGGATLALMSISTTTALITFIILILLTILEFA 205
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 6-186 7.14e-35

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 122.70  E-value: 7.14e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860     6 FDQFMSPS--LLGIPLILISLLFPTLLF---PSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILL 80
Cdd:TIGR01131   2 FSQFDISPitLFSLTLLSLILLLSLLIFlisSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    81 LTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170       180
                  ....*....|....*....|....*.
gi 33243860   161 LTANLTAGHLLIQLISTASTVLLPIM 186
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLLFSLMSSA 187
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 1-178 1.77e-33

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 119.31  E-value: 1.77e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLILISLLFPTL-LFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMIL 79
Cdd:MTH00035   3 INNSIFGQFSPDTILFIPLTLLSSVIALSwLFFINPTNWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFIL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   80 LLTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGV 159
Cdd:MTH00035  83 ILSINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGL 162

                        170
                 ....*....|....*....
gi 33243860  160 RLTANLTAGHLLIQLISTA 178
Cdd:MTH00035 163 RLAANLTAGHLLIFLLSTA 181
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-186 1.29e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 106.41  E-value: 1.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLsfFDQFMSPSLLGIPLILISLLFPTLLFPSpdNRW-ITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMIL 79
Cdd:MTH00157   3 TNL--FSIFDPSTSFNLSLNWLSTFLGLLFIPS--SFWlIPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   80 LLTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180
                 ....*....|....*....|....*..
gi 33243860  160 RLTANLTAGHLLIQLISTASTVLLPIM 186
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMI 185
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-187 1.14e-27

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 104.34  E-value: 1.14e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIPLIL---ISLLFPTLLFPSpdNRWIT-NRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSL 76
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISlswITLLLFLLLMPS--SVWFCpSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   77 MILLLTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLA 156
Cdd:MTH00176  79 FILVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLT 158

                        170       180       190
                 ....*....|....*....|....*....|.
gi 33243860  157 LGVRLTANLTAGHLLIQLISTASTVLLPIMP 187
Cdd:MTH00176 159 LAVRLAANLSAGHLLLGLLGAAMWGLLPVSP 189
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 4-190 8.40e-27

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 102.25  E-value: 8.40e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    4 SFFDQFMSPSLLGIPLILISLLFPTLLFPSPdnRWI-TNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILLLT 82
Cdd:MTH00173   7 SSFDDHNSSFSSLSFLMWLLSLMSLFFFSSS--VWVsSSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLIS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   83 INLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLT 162
Cdd:MTH00173  85 LNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLL 164

                        170       180
                 ....*....|....*....|....*...
gi 33243860  163 ANLTAGHLLIQLISTASTVLLPIMPAVS 190
Cdd:MTH00173 165 ANISAGHIVLTLIGNYLSSSLFSSSVVS 192
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 90-190 7.87e-25

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 94.77  E-value: 7.87e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGH 169
Cdd:cd00310  25 PYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPIELISELIRPLSLSVRLFANMFAGH 104

                        90       100
                ....*....|....*....|.
gi 33243860 170 LLIQLISTASTVLLPIMPAVS 190
Cdd:cd00310 105 LLLALLSGLVPSLLSSVGLLP 125
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 89-177 1.36e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 83.24  E-value: 1.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   89 LPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:MTH00005  93 LPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLAANMSAG 172


                 ....*....
gi 33243860  169 HLLIQLIST 177
Cdd:MTH00005 173 HIVLSLIGI 181
ATP-synt_A pfam00119
ATP synthase A chain;
90-190 2.17e-18

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 79.46  E-value: 2.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIA-LGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:pfam00119  81 PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAG 160

                          90       100
                  ....*....|....*....|..
gi 33243860   169 HLLIQLISTASTVLLPIMPAVS 190
Cdd:pfam00119 161 HLLLLLLAGLIFALLSAGFLLG 182
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-176 8.37e-18

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 78.16  E-value: 8.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGI---PLILISLLFPTLLFpSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLM 77
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLtnsSIMMILVIIVVLLL-FKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   78 ILLLTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLAL 157
Cdd:MTH00172  80 FFIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISL 159

                        170
                 ....*....|....*....
gi 33243860  158 GVRLTANLTAGHLLIQLIS 176
Cdd:MTH00172 160 GVRLAANLSAGHLLFAILA 178
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 1-176 7.19e-16

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 73.50  E-value: 7.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860    1 MNLSFFDQFMSPSLLGIP----------------LILISLLFPTLLFpspDNRWITNRISTLQLWFFQLITKQLMTPLNK 64
Cdd:MTH00175   1 MLAAYFDQFNIIRLITIQaflgdwlvtftnssmmMVLAVIIFWLLLK---GDKLIPNRWQSIMELIYLNIRSVVHDNLGK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   65 KGHKWALILLSLMILLLTINLLGLLPYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALIL 144
Cdd:MTH00175  78 SGQKYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVL 157

                        170       180       190
                 ....*....|....*....|....*....|..
gi 33243860  145 IETTSLLIRPLALGVRLTANLTAGHLLIQLIS 176
Cdd:MTH00175 158 IETLSYLIRAISLGVRLAANISAGHLLFAILS 189
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 24-177 5.34e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 63.03  E-value: 5.34e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   24 LLFPTLLFPSPDNRWITNRISTLQLWFFQLITKQLMTPLNKKGHKWALILLSLMILLLTINLLGLLPYTFTPTTQLSMNL 103
Cdd:MTH00174  45 FLFYTIGAKGNNNTLVPNRILVGLELIYSHFYTVLKDNLGNKGGNYLAFVLSLFILILFGNGLGLFPYVFTPTVHMVITL 124

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33243860  104 ALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAGHLLIQLIST 177
Cdd:MTH00174 125 GLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAANISSGHLLFSIIAS 198
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 90-189 7.94e-11

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 58.93  E-value: 7.94e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860  90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIA-LGHLLPEGTPtPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:COG0356  78 PGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLKHLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAG 156

                        90       100
                ....*....|....*....|.
gi 33243860 169 HLLIQLISTASTVLLPIMPAV 189
Cdd:COG0356 157 HIILLLLAGLAPFLLLGVLSL 177
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 91-188 3.97e-10

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 57.11  E-value: 3.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   91 YTFTPTTQLSMNLALAFPLWLATLLTGLRNQpsiALGHLLPEGTPTPlIPALILIETTSLLIRPLALGVRLTANLTAGHL 170
Cdd:PRK05815  95 LLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HPLLLPIEIISEFSRPISLSLRLFGNMLAGEL 170

                         90
                 ....*....|....*...
gi 33243860  171 LIQLISTASTVLLPIMPA 188
Cdd:PRK05815 171 ILALIALLGGAGLLLALA 188
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 90-177 3.49e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 51.52  E-value: 3.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNqpSIALGHLLPEGTPTPLIP-ALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:MTH00087  72 PYSFSPCGMVEFTFLYALVAWLSTFLSFLSK--SEKFSVYLSKGSDSFLKTfSMLFVEIVSELSRPLALTLRLTVNLMVG 149


                 ....*....
gi 33243860  169 HLLIQLIST 177
Cdd:MTH00087 150 HLISSLLNF 158
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 90-172 1.67e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 44.35  E-value: 1.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIA-LGHLlPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:PRK13419 191 PYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGyLAHL-TGGTHWSLWIIMIPIEFIGLFTKPFALTVRLFANMTAG 269


                 ....
gi 33243860  169 HLLI 172
Cdd:PRK13419 270 HIVI 273
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-172 4.04e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 43.34  E-value: 4.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33243860   94 TPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIE-TTSLLIRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEfIVSPMAKTFALTVRLLANMTAGHVII 296
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 90-168 4.08e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 36.40  E-value: 4.08e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33243860   90 PYTFTPTTQLSMNLALAFPLWLATLLTGLRNQPSIALGHLLPEGTPTPLIPALILIETTSLLIRPLALGVRLTANLTAG 168
Cdd:MTH00050  43 PYIYSPFLFVVFLFVVVFPLFISLFLSRVFDSLNEFFSSFVPVGTPLYICPFVCIAETISYIIRPVVLILRPFINISLG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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