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Conserved domains on  [gi|328797828|gb|AEB40940|]
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ring-finger 213, partial [Bryaninops yongei]

Protein Classification

ATP-binding protein( domain architecture ID 12206295)

ATP-binding protein containing an AAA (ATPases Associated with various cellular Activities) domain functions in an oligomeric complex and undergoes ATP hydrolysis-driven conformational changes, which are ultimately responsible for its function

Gene Ontology:  GO:0005524|GO:0016887
PubMed:  17897320|18466635

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 83-196 2.98e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


:

Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 45.44  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828    83 GIPVIIMGETGCGKTRLIKFLC-ELRKSG-------------VATENMKLVKVHGGTNSDMVYAKVKDAEAMAAINKQDy 148
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALArELGPPGggviyidgedileEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD- 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 328797828   149 gfdsVLFFDEANT-TEAISSIKEVLCDRTIKGQSLKPGCGLQIIAACNP 196
Cdd:smart00382  81 ----VLILDEITSlLDAEQEALLLLLEELRLLLLLKSEKNLTVILTTND 125
 
Name Accession Description Interval E-value
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 83-196 2.98e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 45.44  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828    83 GIPVIIMGETGCGKTRLIKFLC-ELRKSG-------------VATENMKLVKVHGGTNSDMVYAKVKDAEAMAAINKQDy 148
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALArELGPPGggviyidgedileEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD- 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 328797828   149 gfdsVLFFDEANT-TEAISSIKEVLCDRTIKGQSLKPGCGLQIIAACNP 196
Cdd:smart00382  81 ----VLILDEITSlLDAEQEALLLLLEELRLLLLLKSEKNLTVILTTND 125
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 85-196 2.57e-05

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 42.28  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828   85 PVIIMGETGCGKTRLIKFLCEL--RKSGVA---TENMKLVKVHGGTNSDMVYAKVKDAEAMAAINKQDygfdsVLFFDEA 159
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAAlsNRPVFYvqlTRDTTEEDLFGRRNIDPGGASWVDGPLVRAAREGE-----IAVLDEI 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 328797828  160 NT--TEAISSIKEVLCDRTI-----KGQSLKPGCGLQIIAACNP 196
Cdd:pfam07728  76 NRanPDVLNSLLSLLDERRLllpdgGELVKAAPDGFRLIATMNP 119
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 68-196 1.11e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 40.98  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828  68 DNILKILAIHMRFRCGIPVIIMGETGCGKTRLIKFLC-ELRKSGVateNMKLVKVHGGTNSDMVYAKVK--DAEAMAAIN 144
Cdd:cd00009    4 EEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIAnELFRPGA---PFLYLNASDLLEGLVVAELFGhfLVRLLFELA 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 328797828 145 KQDYGfdSVLFFDEANT-TEAISSIKEVLCDRTIKGQSLKPGCglQIIAACNP 196
Cdd:cd00009   81 EKAKP--GVLFIDEIDSlSRGAQNALLRVLETLNDLRIDRENV--RVIGATNR 129
 
Name Accession Description Interval E-value
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 83-196 2.98e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 45.44  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828    83 GIPVIIMGETGCGKTRLIKFLC-ELRKSG-------------VATENMKLVKVHGGTNSDMVYAKVKDAEAMAAINKQDy 148
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALArELGPPGggviyidgedileEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD- 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 328797828   149 gfdsVLFFDEANT-TEAISSIKEVLCDRTIKGQSLKPGCGLQIIAACNP 196
Cdd:smart00382  81 ----VLILDEITSlLDAEQEALLLLLEELRLLLLLKSEKNLTVILTTND 125
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 85-196 2.57e-05

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 42.28  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828   85 PVIIMGETGCGKTRLIKFLCEL--RKSGVA---TENMKLVKVHGGTNSDMVYAKVKDAEAMAAINKQDygfdsVLFFDEA 159
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAAlsNRPVFYvqlTRDTTEEDLFGRRNIDPGGASWVDGPLVRAAREGE-----IAVLDEI 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 328797828  160 NT--TEAISSIKEVLCDRTI-----KGQSLKPGCGLQIIAACNP 196
Cdd:pfam07728  76 NRanPDVLNSLLSLLDERRLllpdgGELVKAAPDGFRLIATMNP 119
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 68-196 1.11e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 40.98  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328797828  68 DNILKILAIHMRFRCGIPVIIMGETGCGKTRLIKFLC-ELRKSGVateNMKLVKVHGGTNSDMVYAKVK--DAEAMAAIN 144
Cdd:cd00009    4 EEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIAnELFRPGA---PFLYLNASDLLEGLVVAELFGhfLVRLLFELA 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 328797828 145 KQDYGfdSVLFFDEANT-TEAISSIKEVLCDRTIKGQSLKPGCglQIIAACNP 196
Cdd:cd00009   81 EKAKP--GVLFIDEIDSlSRGAQNALLRVLETLNDLRIDRENV--RVIGATNR 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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