|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
6-253 |
6.76e-41 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 145.80 E-value: 6.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 6 ATVEECYQECIAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDIAHGA 85
Cdd:PLN02607 185 QALEAAYQEAEAANIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSAS--EFVSVAEIVEAR 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 86 KRQGAEDLIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEHFFTRFLEANAQRLTD 165
Cdd:PLN02607 263 GYKGVAERVHIVYSLSKDLGLPGFRVGTIYSYNDKVVTTARRMSSFTLVSSQTQHLLASMLSDEEFTENYIRTNRERLRK 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 166 TYSKVVAKLRDHGVKDIAvADGAMFVYFKMPG--EELSLEEERFLWQRLVRENRVMVLPGLVFEDARRGWFRICVsANPL 243
Cdd:PLN02607 343 RYEMIVQGLRRAGIECLK-GNAGLFCWMNLSPllETPTREGELALWDSILREVKLNISPGSSCHCSEPGWFRVCF-ANMS 420
|
250
....*....|.
gi 326437829 244 EDTLE-AVDRI 253
Cdd:PLN02607 421 EDTLEvALKRI 431
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
13-255 |
5.27e-35 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 128.23 E-value: 5.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 13 QECIAEGAKApVFIyTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVFDiahgakrqgAED 92
Cdd:cd00609 126 EAAKTPKTKL-LYL-NNPNNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLD---------AYE 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGL--AYGFSTPAEMQEMTAAVIEDEHfftRFLEANAQRLTDTYSKV 170
Cdd:cd00609 195 RVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLlpYTTSGPSTLSQAAAAAALDDGE---EHLEELRERYRRRRDAL 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 171 VAKLRDHGVKDIAVADGAMFVYFKMPGeelsLEEERFLWqRLVRENRVMVLPGLVFEDARRGWFRICVsANPLEDTLEAV 250
Cdd:cd00609 272 LEALKELGPLVVVKPSGGFFLWLDLPE----GDDEEFLE-RLLLEAGVVVRPGSAFGEGGEGFVRLSF-ATPEEELEEAL 345
|
....*
gi 326437829 251 DRIFK 255
Cdd:cd00609 346 ERLAE 350
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
1-253 |
9.87e-34 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 124.72 E-value: 9.87e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 1 MKLDMATVEECYqeciaegAKAPVFIY-TNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAmsIFTTAKVEFTSvf 79
Cdd:pfam00155 122 FHLDFDALEAAL-------KEKPKVVLhTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYA--GFVFGSPDAVA-- 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 80 dIAHGAKRqgaEDLIHIMWGGSKDLGLNGFRIGVLLTrNQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEHFFTRFLEAN 159
Cdd:pfam00155 191 -TRALLAE---GPNLLVVGSFSKAFGLAGWRVGYILG-NAAVISQLRKLARPFYSSTHLQAAAAAALSDPLLVASELEEM 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 160 AQRLTDTYSKVVAKLRDHGVKDIAvADGAMFVYfkmpgEELSLEEERFLWQRLVRENRVMVLPGLVFEdaRRGWFRICVS 239
Cdd:pfam00155 266 RQRIKERRDYLRDGLQAAGLSVLP-SQAGFFLL-----TGLDPETAKELAQVLLEEVGVYVTPGSSPG--VPGWLRITVA 337
|
250
....*....|....
gi 326437829 240 ANPLEDTLEAVDRI 253
Cdd:pfam00155 338 GGTEEELEELLEAI 351
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
2-253 |
1.47e-31 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 119.85 E-value: 1.47e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 2 KLDMATVEECyqecIAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDI 81
Cdd:COG0436 150 LPDPEALEAA----ITPRTKA--IVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGA--EHVSILSL 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 82 AhGAKrqgaEDLIHIMwGGSKDLGLNGFRIGVLLTrNQELKKCLRGLA--YGFSTPAEMQE-MTAAVIEDEHFFTRFLEA 158
Cdd:COG0436 222 P-GLK----DRTIVIN-SFSKSYAMTGWRIGYAVG-PPELIAALLKLQsnLTSCAPTPAQYaAAAALEGPQDYVEEMRAE 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 159 NAQRLtDTyskVVAKLRDHGVkDIAVADGAMFVYFKMPGEELSLEEerfLWQRLVRENRVMVLPGLVFEDARRGWFRICV 238
Cdd:COG0436 295 YRRRR-DL---LVEGLNEIGL-SVVKPEGAFYLFADVPELGLDSEE---FAERLLEEAGVAVVPGSAFGPAGEGYVRISY 366
|
250
....*....|....*
gi 326437829 239 sANPLEDTLEAVDRI 253
Cdd:COG0436 367 -ATSEERLEEALERL 380
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
21-253 |
2.30e-12 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 65.96 E-value: 2.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 21 KAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIAhgakrqgAEDLIHIMWGG 100
Cdd:TIGR01264 168 KTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGAT--FEPLASLS-------STVPILSCGGL 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 101 SKDLGLNGFRIGVLLTRNQE---------LKKcLRGLAYGFSTPAE--MQEMTAAVIEDEHFFTR-FLEANAQRLTDTYS 168
Cdd:TIGR01264 239 AKRWLVPGWRLGWIIIHDRRgilrdirdgLVK-LSQRILGPCTIVQgaLPSILLRTPQEYFDGTLsVLESNAMLCYGALA 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 169 KVVaklrdhGVkDIAVADGAMFVYFKMPGEEL-SLEEERFLWQRLVRENRVMVLPGLVFEDArrGWFRIcVSANPLEDTL 247
Cdd:TIGR01264 318 AVP------GL-RPVMPSGAMYMMVGIEMEHFpEFKNDVEFTERLVAEQSVFCLPGSCFEYP--GFFRV-VLTVPVVMME 387
|
....*.
gi 326437829 248 EAVDRI 253
Cdd:TIGR01264 388 EACSRI 393
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
6-253 |
6.76e-41 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 145.80 E-value: 6.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 6 ATVEECYQECIAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDIAHGA 85
Cdd:PLN02607 185 QALEAAYQEAEAANIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSAS--EFVSVAEIVEAR 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 86 KRQGAEDLIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEHFFTRFLEANAQRLTD 165
Cdd:PLN02607 263 GYKGVAERVHIVYSLSKDLGLPGFRVGTIYSYNDKVVTTARRMSSFTLVSSQTQHLLASMLSDEEFTENYIRTNRERLRK 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 166 TYSKVVAKLRDHGVKDIAvADGAMFVYFKMPG--EELSLEEERFLWQRLVRENRVMVLPGLVFEDARRGWFRICVsANPL 243
Cdd:PLN02607 343 RYEMIVQGLRRAGIECLK-GNAGLFCWMNLSPllETPTREGELALWDSILREVKLNISPGSSCHCSEPGWFRVCF-ANMS 420
|
250
....*....|.
gi 326437829 244 EDTLE-AVDRI 253
Cdd:PLN02607 421 EDTLEvALKRI 431
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
2-253 |
1.15e-36 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 134.88 E-value: 1.15e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 2 KLDMATVEECYQECIAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDI 81
Cdd:PLN02450 172 QITESALEEAYQQAQKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSP--GFVSVMEV 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 82 AHGAKRQGAE--DLIHIMWGGSKDLGLNGFRIGVLLTRNQEL-----KKCLRGLaygfsTPAEMQEMTAAVIEDEHFFTR 154
Cdd:PLN02450 250 LKDRKLENTDvsNRVHIVYSLSKDLGLPGFRVGAIYSNDEMVvsaatKMSSFGL-----VSSQTQYLLSALLSDKKFTKN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 155 FLEANAQRLTDTYSKVVAKLRDHGVKDIAvADGAMFVYFKMPG--EELSLEEERFLWQRLVRENRVMVLPGLVFEDARRG 232
Cdd:PLN02450 325 YLEENQKRLKQRQKKLVSGLEAAGIKCLK-SNAGLFCWVDMRHllKSNTFEAEMELWKKIVYEVKLNISPGSSCHCTEPG 403
|
250 260
....*....|....*....|..
gi 326437829 233 WFRICVsANPLEDTLE-AVDRI 253
Cdd:PLN02450 404 WFRVCF-ANMSEETLDlAMKRL 424
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
13-255 |
5.27e-35 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 128.23 E-value: 5.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 13 QECIAEGAKApVFIyTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVFDiahgakrqgAED 92
Cdd:cd00609 126 EAAKTPKTKL-LYL-NNPNNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLD---------AYE 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGL--AYGFSTPAEMQEMTAAVIEDEHfftRFLEANAQRLTDTYSKV 170
Cdd:cd00609 195 RVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLlpYTTSGPSTLSQAAAAAALDDGE---EHLEELRERYRRRRDAL 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 171 VAKLRDHGVKDIAVADGAMFVYFKMPGeelsLEEERFLWqRLVRENRVMVLPGLVFEDARRGWFRICVsANPLEDTLEAV 250
Cdd:cd00609 272 LEALKELGPLVVVKPSGGFFLWLDLPE----GDDEEFLE-RLLLEAGVVVRPGSAFGEGGEGFVRLSF-ATPEEELEEAL 345
|
....*
gi 326437829 251 DRIFK 255
Cdd:cd00609 346 ERLAE 350
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
1-253 |
9.87e-34 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 124.72 E-value: 9.87e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 1 MKLDMATVEECYqeciaegAKAPVFIY-TNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAmsIFTTAKVEFTSvf 79
Cdd:pfam00155 122 FHLDFDALEAAL-------KEKPKVVLhTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYA--GFVFGSPDAVA-- 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 80 dIAHGAKRqgaEDLIHIMWGGSKDLGLNGFRIGVLLTrNQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEHFFTRFLEAN 159
Cdd:pfam00155 191 -TRALLAE---GPNLLVVGSFSKAFGLAGWRVGYILG-NAAVISQLRKLARPFYSSTHLQAAAAAALSDPLLVASELEEM 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 160 AQRLTDTYSKVVAKLRDHGVKDIAvADGAMFVYfkmpgEELSLEEERFLWQRLVRENRVMVLPGLVFEdaRRGWFRICVS 239
Cdd:pfam00155 266 RQRIKERRDYLRDGLQAAGLSVLP-SQAGFFLL-----TGLDPETAKELAQVLLEEVGVYVTPGSSPG--VPGWLRITVA 337
|
250
....*....|....
gi 326437829 240 ANPLEDTLEAVDRI 253
Cdd:pfam00155 338 GGTEEELEELLEAI 351
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
2-253 |
1.47e-31 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 119.85 E-value: 1.47e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 2 KLDMATVEECyqecIAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDI 81
Cdd:COG0436 150 LPDPEALEAA----ITPRTKA--IVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGA--EHVSILSL 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 82 AhGAKrqgaEDLIHIMwGGSKDLGLNGFRIGVLLTrNQELKKCLRGLA--YGFSTPAEMQE-MTAAVIEDEHFFTRFLEA 158
Cdd:COG0436 222 P-GLK----DRTIVIN-SFSKSYAMTGWRIGYAVG-PPELIAALLKLQsnLTSCAPTPAQYaAAAALEGPQDYVEEMRAE 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 159 NAQRLtDTyskVVAKLRDHGVkDIAVADGAMFVYFKMPGEELSLEEerfLWQRLVRENRVMVLPGLVFEDARRGWFRICV 238
Cdd:COG0436 295 YRRRR-DL---LVEGLNEIGL-SVVKPEGAFYLFADVPELGLDSEE---FAERLLEEAGVAVVPGSAFGPAGEGYVRISY 366
|
250
....*....|....*
gi 326437829 239 sANPLEDTLEAVDRI 253
Cdd:COG0436 367 -ATSEERLEEALERL 380
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
2-253 |
8.14e-31 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 119.42 E-value: 8.14e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 2 KLDMATVEECYQECIAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFttAKVEFTSVFDI 81
Cdd:PLN02376 180 KLTVDAADWAYKKAQESNKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVF--AGGDFVSVAEV 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 82 AHGAKRQGAE-DLIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEHFFTRFLEANA 160
Cdd:PLN02376 258 VNDVDISEVNvDLIHIVYSLSKDMGLPGFRVGIVYSFNDSVVSCARKMSSFGLVSSQTQLMLASMLSDDQFVDNFLMESS 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 161 QRLtdtysKVVAKLRDHGVK--DIA--VADGAMFVYFKMPG---EELSLEEERFLWQRLVRENRVMVLPGLVFEDARRGW 233
Cdd:PLN02376 338 RRL-----GIRHKVFTTGIKkaDIAclTSNAGLFAWMDLRHllrDRNSFESEIELWHIIIDKVKLNVSPGSSFRCTEPGW 412
|
250 260
....*....|....*....|.
gi 326437829 234 FRICVsANPLEDTLE-AVDRI 253
Cdd:PLN02376 413 FRICF-ANMDDDTLHvALGRI 432
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
25-253 |
3.60e-18 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 82.91 E-value: 3.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 25 FIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIAHGAKRqgaedliHIMWGGSKDL 104
Cdd:PTZ00433 181 LIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGAT--FTSVADFDTTVPR-------VILGGTAKNL 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 105 GLNGFRIG--VLLTRNQELKKCLRG---LAYGFSTP-AEMQEMTAAVIEDEHffTRFLEANAQRLTDTySKVVAKL--RD 176
Cdd:PTZ00433 252 VVPGWRLGwlLLVDPHGNGGDFLDGmkrLGMLVCGPcSVVQAALGEALLNTP--QEHLEQIVAKLEEG-AMVLYNHigEC 328
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 326437829 177 HGVKdIAVADGAMFVYFKMPGEEL-SLEEERFLWQRLVRENRVMVLPGLVFEDArrGWFRICVSaNPLEDTLEAVDRI 253
Cdd:PTZ00433 329 IGLS-PTMPRGSMFLMSRLDLEKFrDIKSDVEFYEKLLEEENVQVLPGEIFHMP--GFTRLTIS-RPVEVLREAVERI 402
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
26-252 |
1.40e-14 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 72.28 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 26 IYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEfTSVFDIAhgakrqGAEDLIHIMWGGSKDLG 105
Cdd:PRK06108 163 FINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRA-PSFLDIA------EPDDRIIFVNSFSKNWA 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 106 LNGFRIGVLLTRnQELKKCLRGL-AYGFS-TPAEMQEMTAAVIEDEHFFTRFLEANAQRLTDTyskVVAKLRDHGVKDIA 183
Cdd:PRK06108 236 MTGWRLGWLVAP-PALGQVLEKLiEYNTScVAQFVQRAAVAALDEGEDFVAELVARLRRSRDH---LVDALRALPGVEVA 311
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 326437829 184 VADGAMFVYFKMPGEELSLEeerfLWQRLVRENRVMVLPGLVFEDARRGWFRICVSANPlEDTLEAVDR 252
Cdd:PRK06108 312 KPDGAMYAFFRIPGVTDSLA----LAKRLVDEAGLGLAPGTAFGPGGEGFLRWCFARDP-ARLDEAVER 375
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
16-253 |
1.68e-12 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 66.29 E-value: 1.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 16 IAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSwCLAK-QVHLISDEIYAMSIFTtakveftsvfDIAHGAKRQGAEDLI 94
Cdd:PRK07309 161 LEQGDKLKAVILNYPANPTGVTYSREQIKALAD-VLKKyDIFVISDEVYSELTYT----------GEPHVSIAEYLPDQT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 95 HIMWGGSKDLGLNGFRIGVLLTRNQ---ELKKCLRGLAYGFSTPAEMqemtAAViedehfftrflEA------NAQRLTD 165
Cdd:PRK07309 230 ILINGLSKSHAMTGWRIGLIFAPAEftaQLIKSHQYLVTAATTMAQF----AAV-----------EAltngkdDALPMKK 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 166 TYSK----VVAKLRDHGVKdIAVADGAMFVYFKMPgEELSLEEERFLwQRLVRENRVMVLPGLVFEDARRGWFRICVSAN 241
Cdd:PRK07309 295 EYIKrrdyIIEKMTDLGFK-IIKPDGAFYIFAKIP-AGYNQDSFKFL-QDFARKKAVAFIPGAAFGPYGEGYVRLSYAAS 371
|
250
....*....|..
gi 326437829 242 pLEDTLEAVDRI 253
Cdd:PRK07309 372 -METIKEAMKRL 382
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
21-253 |
2.30e-12 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 65.96 E-value: 2.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 21 KAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIAhgakrqgAEDLIHIMWGG 100
Cdd:TIGR01264 168 KTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGAT--FEPLASLS-------STVPILSCGGL 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 101 SKDLGLNGFRIGVLLTRNQE---------LKKcLRGLAYGFSTPAE--MQEMTAAVIEDEHFFTR-FLEANAQRLTDTYS 168
Cdd:TIGR01264 239 AKRWLVPGWRLGWIIIHDRRgilrdirdgLVK-LSQRILGPCTIVQgaLPSILLRTPQEYFDGTLsVLESNAMLCYGALA 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 169 KVVaklrdhGVkDIAVADGAMFVYFKMPGEEL-SLEEERFLWQRLVRENRVMVLPGLVFEDArrGWFRIcVSANPLEDTL 247
Cdd:TIGR01264 318 AVP------GL-RPVMPSGAMYMMVGIEMEHFpEFKNDVEFTERLVAEQSVFCLPGSCFEYP--GFFRV-VLTVPVVMME 387
|
....*.
gi 326437829 248 EAVDRI 253
Cdd:TIGR01264 388 EACSRI 393
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
26-253 |
3.45e-12 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 65.44 E-value: 3.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 26 IYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIAHGAKRqgaedlihIMWGG-SKDL 104
Cdd:TIGR01265 174 VVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAP--FIPMASFASIVPV--------LSLGGiSKRW 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 105 GLNGFRIGVLLTRN----------QELKKCLrGLAYGFSTPAemQEMTAAVIE--DEHFFTR---FLEANAQRLTDTYSK 169
Cdd:TIGR01265 244 VVPGWRLGWIIIHDphgifrdtvlQGLKNLL-QRILGPATIV--QGALPDILEntPQEFFDGkisVLKSNAELCYEELKD 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 170 VVaklrdhGVkDIAVADGAMFVyfkMPGEELSLEEE-----RFLwQRLVRENRVMVLPGLVFEdaRRGWFRIcVSANPLE 244
Cdd:TIGR01265 321 IP------GL-VCPKPEGAMYL---MVKLELELFPEikddvDFC-EKLAREESVICLPGSAFG--LPNWVRI-TITVPES 386
|
....*....
gi 326437829 245 DTLEAVDRI 253
Cdd:TIGR01265 387 MLEEACSRI 395
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
24-253 |
1.34e-11 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 63.61 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 24 VFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAkvEFTSVFDIAHGAKRQgaedLIhIMWGGSKD 103
Cdd:PRK05764 167 ALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGA--EFTSIASLSPELRDR----TI-TVNGFSKA 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 104 LGLNGFRIGVLLTrNQELKKCLRGLA-YGFSTPAEMQEMTA--AVIEDEHFFTRFLEANAQRLtDTyskVVAKLRDHGVK 180
Cdd:PRK05764 240 YAMTGWRLGYAAG-PKELIKAMSKLQsHSTSNPTSIAQYAAvaALNGPQDEVEEMRQAFEERR-DL---MVDGLNEIPGL 314
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 326437829 181 DIAVADGA--MFVYFKMPGEELSLEEERFLwQRLVRENRVMVLPGLVFEDarRGWFRIcvS-ANPLEDTLEAVDRI 253
Cdd:PRK05764 315 ECPKPEGAfyVFPNVSKLLGKSITDSLEFA-EALLEEAGVAVVPGIAFGA--PGYVRL--SyATSLEDLEEGLERI 385
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
3-253 |
2.92e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 62.86 E-value: 2.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 3 LDMATVEECYQEciaeGAKapVFIYTNPHNPSGTIFCAKQTEALVSwcLAKQ--VHLISDEIYAMSIFTTAkvEFTSVFd 80
Cdd:PRK06207 166 LDLDQLEEAFKA----GVR--VFLFSNPNNPAGVVYSAEEIAQIAA--LARRygATVIVDQLYSRLLYDGT--SYTHLR- 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 81 iahgAKRQGAEDLIHIMwGGSKDLGLNGFRIGV------LLTRNQELKK--CLRGLAYG-------FSTPAE-MQEMTAA 144
Cdd:PRK06207 235 ----ALPIDPENVITIM-GPSKTESLSGYRLGVafgspaIIDRMEKLQAivSLRAAGYSqavlrtwFSEPDGwMKDRIAR 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 145 --VIEDEhfftrfleanaqrltdtyskVVAKLRdhGVKDIAV--ADGAMFVYFKMPGEELSLEEerflWQRLVR-ENRVM 219
Cdd:PRK06207 310 hqAIRDD--------------------LLRVLR--GVEGVFVraPQAGSYLFPRLPRLAVSLHD----FVKILRlQAGVI 363
|
250 260 270
....*....|....*....|....*....|....
gi 326437829 220 VLPGLVFEDARRGWFRICVSANPlEDTLEAVDRI 253
Cdd:PRK06207 364 VTPGTEFSPHTADSIRLNFSQDH-AAAVAAAERI 396
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
1-255 |
2.20e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 60.21 E-value: 2.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 1 MKLDMATVEEcyqeciAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQ------VHLISDEIYAMSIFTTAKVe 74
Cdd:PRK06836 154 FQPDLDALEA------AITPKTKAVIINSPNNPTGVVYSEETLKALAALLEEKSkeygrpIYLISDEPYREIVYDGAEV- 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 75 fTSVFDIahgakrqgAEDLIhIMWGGSKDLGLNGFRIGVLLTRN-----QELKKCL----RGLayGF-STPAEMQEMTAA 144
Cdd:PRK06836 227 -PYIFKY--------YDNSI-VVYSFSKSLSLPGERIGYIAVNPemedaDDLVAALvfanRIL--GFvNAPALMQRVVAK 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 145 VIeDEHFFTRFLEANAQRLTDTyskvvakLRDHGVkDIAVADGAMFVYFKMPGEelslEEERFLwQRLVRENRVMVlPGL 224
Cdd:PRK06836 295 CL-DATVDVSIYKRNRDLLYDG-------LTELGF-ECVKPQGAFYLFPKSPEE----DDVAFC-EKAKKHNLLLV-PGS 359
|
250 260 270
....*....|....*....|....*....|...
gi 326437829 225 VFedARRGWFRI--CVSANPLEDTLEAVDRIFK 255
Cdd:PRK06836 360 GF--GCPGYFRLsyCVDTETIERSLPAFEKLAK 390
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
12-238 |
1.09e-09 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 57.83 E-value: 1.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 12 YQECIAEGAKApVFIyTNPHNPSGTIFCAKQTEALVSWClAKQVHLISDEIYamsifttakVEFTSVFD--IAHGAKRqg 89
Cdd:COG0079 129 LLAAITERTDL-VFL-CNPNNPTGTLLPREELEALLEAL-PADGLVVVDEAY---------AEFVPEEDsaLPLLARY-- 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 90 aEDLIHI--MwggSKDLGLNGFRIGVLLTrNQELKKCLRGLA--YGFSTPAemQEMTAAVIEDEHFFtrflEANAQRLTD 165
Cdd:COG0079 195 -PNLVVLrtF---SKAYGLAGLRLGYAIA-SPELIAALRRVRgpWNVNSLA--QAAALAALEDRAYL----EETRARLRA 263
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 326437829 166 TYSKVVAKLRDHGVKdiaVADG-AMFVYFKMPgeelslEEERFLWQRLvRENRVMV----LPGLvfedarRGWFRICV 238
Cdd:COG0079 264 ERERLAAALRALGLT---VYPSqANFVLVRVP------EDAAELFEAL-LERGILVrdfsSFGL------PDYLRITV 325
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
3-84 |
3.00e-09 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 56.90 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 3 LDMATVEECYQECIAEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTaKVEFTSVFDIA 82
Cdd:PTZ00377 200 LDQEELEEAYEQAVRNGITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDG-EKPFISFRKVL 278
|
..
gi 326437829 83 HG 84
Cdd:PTZ00377 279 LE 280
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
13-253 |
4.81e-09 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 56.27 E-value: 4.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 13 QECIAEGAKAPVFIYtnPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTakvEFTSVfdiahgAKRQGAED 92
Cdd:PRK07683 155 ENAITEKTRCVVLPY--PSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ---PHTSI------AHFPEMRE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGLAYGFSTPAEMQEMTAaviedehfftrfLEA------NAQRLTDT 166
Cdd:PRK07683 224 KTIVINGLSKSHSMTGWRIGFLFAPSYLAKHILKVHQYNVTCASSISQYAA------------LEAltagkdDAKMMRHQ 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 167 YSK----VVAKLRDHGVkDIAVADGAMFVY-----FKMPGEELSLEeerflwqrLVRENRVMVLPGLVFEDARRGWFRIC 237
Cdd:PRK07683 292 YKKrrdyVYNRLISMGL-DVEKPTGAFYLFpsighFTMSSFDFALD--------LVEEAGLAVVPGSAFSEYGEGYVRLS 362
|
250
....*....|....*.
gi 326437829 238 VsANPLEDTLEAVDRI 253
Cdd:PRK07683 363 Y-AYSIETLKEGLDRL 377
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
1-252 |
1.06e-08 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 54.96 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 1 MKLDMATVEECYQEC----------------IAEGAKAPVFIytNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYA 64
Cdd:PRK07550 129 MWLDMLGIRPVYLPCdegpgllpdpaaaealITPRTRAIALV--TPNNPTGVVYPPELLHELYDLARRHGIALILDETYR 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 65 msifttakvEFTSVFDIAHG--AKRQGAEDLIHIMwGGSKDLGLNGFRIGVLLT---RNQELKKCL------------RG 127
Cdd:PRK07550 207 ---------DFDSGGGAPHDlfADPDWDDTLVHLY-SFSKSYALTGHRVGAVVAspaRIAEIEKFMdtvaicaprigqIA 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 128 LAYGFSTPAEMQEMTAAVIEDEHfftrfleanaqrltDTYSKVVAKLRDHGVkdiaVADGAMFVYFKMPGEELSleeERF 207
Cdd:PRK07550 277 VAWGLPNLADWRAGNRAEIARRR--------------DAFRAVFARLPGWEL----LASGAYFAYVRHPFPDRP---SRE 335
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 326437829 208 LWQRLVRENRVMVLPGLVFEDARRGWFRICVsANPLEDTL-EAVDR 252
Cdd:PRK07550 336 VARRLAKEAGILCLPGTMFGPGQEGYLRLAF-ANADVAGIgELVER 380
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
16-253 |
1.14e-08 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 55.13 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 16 IAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVfdiahgakrQGAEDLIH 95
Cdd:PRK07682 151 ITAKTKA--ILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDEAYTSFASI---------KGMRERTI 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 96 IMWGGSKDLGLNGFRIGVLLTRNQELKKCLRGLAYGFSTPAEMQEMTAaviedehfftrfLEA------NAQRLTDTYSK 169
Cdd:PRK07682 220 LISGFSKGFAMTGWRLGFIAAPVYFSEAMLKIHQYSMMCAPTMAQFAA------------LEAlragndDVIRMRDSYRK 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 170 ----VVAKLRDHGVkDIAVADGAMFVYFKMPGEELSLEEerfLWQRLVRENRVMVLPGLVFEDARRGWFRiCVSANPLED 245
Cdd:PRK07682 288 rrnfFVTSFNEIGL-TCHVPGGAFYAFPSISSTGLSSEE---FAEQLLLEEKVAVVPGSVFGESGEGFIR-CSYATSLEQ 362
|
....*...
gi 326437829 246 TLEAVDRI 253
Cdd:PRK07682 363 LQEAMKRM 370
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
10-123 |
2.33e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 54.09 E-value: 2.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 10 ECYQECIAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIahgakrQG 89
Cdd:PRK07568 153 EEIEKLITPKTKA--ILISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLK--YTSALSL------EG 222
|
90 100 110
....*....|....*....|....*....|....
gi 326437829 90 AEDLIHIMWGGSKDLGLNGFRIGVLLTRNQELKK 123
Cdd:PRK07568 223 LEDRVIIIDSVSKRYSACGARIGCLISKNKELIA 256
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
13-255 |
1.44e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 51.64 E-value: 1.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 13 QECIAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFttaKVEFTSVfdiahgAKRQGAED 92
Cdd:PRK06348 156 EALITSKTKA--IILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSF---YEDFVPM------ATLAGMPE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGGSKDLGLNGFRIGVLLTR---NQELKKCLRGLAYGFSTPAEMQEMTAAVIEDEhFFTRFLEANAQRLTDTYSK 169
Cdd:PRK06348 225 RTITFGSFSKDFAMTGWRIGYVIAPdyiIETAKIINEGICFSAPTISQRAAIYALKHRDT-IVPLIKEEFQKRLEYAYKR 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 170 V--VAKLRDHGVKdiavADGAMFVYFKMPGeeLSLEEerfLWQRLVRENRVMVLPGLVFEDARRGWFRICVSANpLEDTL 247
Cdd:PRK06348 304 IesIPNLSLHPPK----GSIYAFINIKKTG--LSSVE---FCEKLLKEAHVLVIPGKAFGESGEGYIRLACTVG-IEVLE 373
|
....*...
gi 326437829 248 EAVDRIFK 255
Cdd:PRK06348 374 EAFNRIEK 381
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
30-255 |
4.59e-07 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 50.26 E-value: 4.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 30 PHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveftsvfdiaHGAKRQGAEDLIHIMWGGSKDLGLNGF 109
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAK----------HYPMIKYAPDNTILANSFSKTFAMTGW 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 110 RIGVLLTRNQELKKCLRGLAYGFSTPAE-MQEMTAAVIEDEhfftRFLEAnAQRLTDTYSK----VVAKLRDHGVKDIAV 184
Cdd:PRK08361 245 RLGFVIAPEQVIKDMIKLHAYIIGNVASfVQIAGIEALRSK----ESWKA-VEEMRKEYNErrklVLKRLKEMPHIKVFE 319
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 326437829 185 ADGAMFVYFKMPGEELSLEEerfLWQRLVRENRVMVLPGLVFEDARRGWFRICVsANPLEDTLEAVDRIFK 255
Cdd:PRK08361 320 PKGAFYVFANIDETGMSSED---FAEWLLEKARVVVIPGTAFGKAGEGYIRISY-ATSKEKLIEAMERMEK 386
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
16-253 |
5.10e-07 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 50.19 E-value: 5.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 16 IAEGAKAPVFIytNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVfdiahgakrqGAEDLIH 95
Cdd:PRK08363 163 ITEKTKAIAVI--NPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEGKHVSPGSL----------TKDVPVI 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 96 IMWGGSKDLGLNGFRIGVLLTRNQE-----LKKCLRGLA---YGFSTPAEMqemtAAViedehfftRFLEANAQRLTDtY 167
Cdd:PRK08363 231 VMNGLSKVYFATGWRLGYIYFVDPEgklaeVREAIDKLArirLCPNTPAQF----AAI--------AGLTGPMDYLEE-Y 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 168 SKVVAKLRDHGVKDI--------AVADGAMFVYFKMpgEELSLEEERFLWQRLVRENRVMVLPGLVFEDARRGWFRIcVS 239
Cdd:PRK08363 298 MKKLKERRDYIYKRLneipgistTKPQGAFYIFPRI--EEGPWKDDKEFVLDVLHEAHVLFVHGSGFGEYGAGHFRL-VF 374
|
250
....*....|....
gi 326437829 240 ANPLEDTLEAVDRI 253
Cdd:PRK08363 375 LPPVEILEEAMDRF 388
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
3-253 |
5.59e-07 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 49.70 E-value: 5.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 3 LDMATVEECyqecIAEGAKApvFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKveFTSVFDIA 82
Cdd:COG1168 149 IDFDDLEAK----LDPGVKL--LLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHK--HTPFASLS 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 83 HGAkrqgAEDLIhIMWGGSKDLGLNGFRIGVLLTRNQEL----KKCLRGLAYG----FSTPAemqeMTAA---------- 144
Cdd:COG1168 221 EEA----ADRTI-TLTSPSKTFNLAGLKASYAIIPNPALrarfARALEGLGLPspnvLGLVA----TEAAyregeewlde 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 145 VIEdehfftrFLEANAQRLTDTyskvvakLRDH--GVKdIAVADGA--MFVYFkmpgEELSLEEERfLWQRLVRENRVMV 220
Cdd:COG1168 292 LLA-------YLRGNRDLLAEF-------LAEHlpGVK-VTPPEATylAWLDC----RALGLDDEE-LAEFLLEKAGVAL 351
|
250 260 270
....*....|....*....|....*....|....
gi 326437829 221 LPGLVFEDARRGWFRICVsANPLEdTL-EAVDRI 253
Cdd:COG1168 352 SDGATFGEGGEGFVRLNF-ACPRA-VLeEALERL 383
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
13-253 |
1.20e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 48.91 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 13 QECIAEGAKAPVFIytNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYamSIFTTAKVEFTSVFDIAhgakrqGAED 92
Cdd:PRK05957 154 EQAITPKTRAIVTI--SPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAY--EYFTYDGVKHFSPGSIP------GSGN 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGGSKDLGLNGFRIGVLLTRN---QELKK-------ClrglaygfsTPAEMQEMTAAVIED-EHFFTRFLEANAQ 161
Cdd:PRK05957 224 HTISLYSLSKAYGFASWRIGYMVIPIhllEAIKKiqdtiliC---------PPVVSQYAALGALQVgKSYCQQHLPEIAQ 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 162 RltdtYSKVVAKLRD-HGVKDIAVADGAMFVYFK----MPGEELSleeerflwQRLVRENRVMVLPGLVFEDARRGWFRI 236
Cdd:PRK05957 295 V----RQILLKSLGQlQDRCTLHPANGAFYCFLKvntdLNDFELV--------KQLIREYRVAVIPGTTFGMKNGCYLRI 362
|
250
....*....|....*..
gi 326437829 237 CVSANPLEDTLEAVDRI 253
Cdd:PRK05957 363 AYGALQKATAKEGIERL 379
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
15-126 |
4.14e-06 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 47.31 E-value: 4.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 15 CIAEGAKapVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYA-MSIFTTAKVEFTSVFDIAhgakrqgAEDL 93
Cdd:TIGR04350 153 AITEKAR--LLLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHAdLVYPPNKHIPLASLSPEP-------AERT 223
|
90 100 110
....*....|....*....|....*....|...
gi 326437829 94 IHIMwGGSKDLGLNGFRIGVLLTRNQELKKCLR 126
Cdd:TIGR04350 224 VTLL-SPGKTFNIAGLNISFAIIPNPELRRAFQ 255
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
14-247 |
9.85e-06 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 46.16 E-value: 9.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 14 ECIA-EGAKAPVFIytNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVFdiahgakrqgAED 92
Cdd:PLN00143 164 EAIAdENTIAMVII--NPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGLF----------ASI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 93 LIHIMWGG-SKDLGLNGFRIGVLLTRNQE--LKKC------LRGLAYGFSTPAEMQEMTAAVIED--EHFFTRFLEANAQ 161
Cdd:PLN00143 232 VPVITLGSiSKRWMIPGWGLGWLVTCDPSglLQICeiadsiKKALNPAPFPPTFIQAAIPEILEKttEDFFSKTINILRA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 162 RLTDTYSKvvaklrdhgVKDIAV------ADGAMFVYFKMpgeELSL----EEERFLWQRLVRENRVMVLPGLVFedARR 231
Cdd:PLN00143 312 ALAFCYDK---------LKEIPCimcpqkAEGAFFALVKL---NLLLlediEDDMEFCLKLAKEESLIILPGVTV--GLK 377
|
250
....*....|....*...
gi 326437829 232 GWFRI--CVSANPLEDTL 247
Cdd:PLN00143 378 NWLRItfAVEQSSLEDGL 395
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
17-72 |
8.94e-05 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 43.10 E-value: 8.94e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 326437829 17 AEGAKAPVFIYTNPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAK 72
Cdd:PRK07777 155 AVTPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGAR 210
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
16-253 |
2.95e-04 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 41.56 E-value: 2.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 16 IAEGAKapvFIYTN-PHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSVfdiaHGAKRQGAEdlI 94
Cdd:PRK06290 176 IKEKAK---LLYLNyPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDGKPLSFLSV----PGAKEVGVE--I 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 95 HIMwggSKDLGLNGFRIGVLLTrNQELKKclrglayGFSTPAE---------MQEMTAAVIEDEhfftRFLEANAQRLTD 165
Cdd:PRK06290 247 HSL---SKAYNMTGWRLAFVVG-NELIVK-------AFATVKDnndsgqfiaIQKAGIYALDHP----EITEKIREKYSR 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 166 TYSKVVAKLRDHGVKdIAVADGAMFVYFKMP-----GEELSLEEErfLWQRLVRENRVMVLPglvFEDA----RrgwFRI 236
Cdd:PRK06290 312 RLDKLVKILNEVGFK-AEMPGGTFYLYVKAPkgtksGIKFENAEE--FSQYLIKEKLISTVP---WDDAghflR---FSV 382
|
250
....*....|....*..
gi 326437829 237 CVSANPLEDTLEAVDRI 253
Cdd:PRK06290 383 TFEAKDEEEEDRILEEI 399
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
30-253 |
5.53e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 40.81 E-value: 5.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 30 PHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMsifTTAKVEFTSVFdiahgakrqGAEDLIHIMWGGSKDLGLNGF 109
Cdd:PRK08960 174 PANPTGTLLSRDELAALSQALRARGGHLVVDEIYHG---LTYGVDAASVL---------EVDDDAFVLNSFSKYFGMTGW 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 326437829 110 RIGVLLTRN---QELKKCLRGLAYGFSTPAemQEMTAAVIEDEHffTRFLEANA---QRLTDTyskVVAKLRDHGVkDIA 183
Cdd:PRK08960 242 RLGWLVAPPaavPELEKLAQNLYISASTPA--QHAALACFEPET--LAILEARRaefARRRDF---LLPALRELGF-GIA 313
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 326437829 184 V-ADGAMFVYFKMpgEELSLEEERFLwQRLVRENRVMVLPGLVF-EDARRGWFRICVSANpLEDTLEAVDRI 253
Cdd:PRK08960 314 VePQGAFYLYADI--SAFGGDAFAFC-RHFLETEHVAFTPGLDFgRHQAGQHVRFAYTQS-LPRLQEAVERI 381
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
30-78 |
1.09e-03 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 39.85 E-value: 1.09e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 326437829 30 PHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIYAMSIFTTAKVEFTSV 78
Cdd:PLN00175 196 PHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGDHISMASL 244
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
24-63 |
1.40e-03 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 39.51 E-value: 1.40e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 326437829 24 VFIYTnPHNPSGTIFCAKQTEALVSWCLAKQVHLISDEIY 63
Cdd:PRK09082 167 IILNT-PHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVY 205
|
|
| |
