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Conserved domains on  [gi|326432697|gb|EGD78267|]
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hypothetical protein PTSG_09332 [Salpingoeca rosetta]

Protein Classification

transmembrane 220 family protein( domain architecture ID 144901)

transmembrane 220 (TMEM220) family protein similar to human transmembrane protein 220, which is a DNA methylation marker in human gastric cancer

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TMEM220 super family cl20941
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
19-66 9.72e-08

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


The actual alignment was detected with superfamily member pfam15071:

Pssm-ID: 434437  Cd Length: 100  Bit Score: 48.48  E-value: 9.72e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 326432697   19 FFAACGWAQVNDPDPERWVTFYVVCGSVTaLVWAATAAEATGSTAAAL 66
Cdd:pfam15071   1 FFALAAYVQLNDPDPYLWVPIYLLPALLC-LLAALGPAVTGLWRALAV 47
 
Name Accession Description Interval E-value
TMEM220 pfam15071
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
19-66 9.72e-08

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


Pssm-ID: 434437  Cd Length: 100  Bit Score: 48.48  E-value: 9.72e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 326432697   19 FFAACGWAQVNDPDPERWVTFYVVCGSVTaLVWAATAAEATGSTAAAL 66
Cdd:pfam15071   1 FFALAAYVQLNDPDPYLWVPIYLLPALLC-LLAALGPAVTGLWRALAV 47
 
Name Accession Description Interval E-value
TMEM220 pfam15071
Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. ...
19-66 9.72e-08

Transmembrane family 220, helix; Transmembrane 220 (TMEM220) is a domain of unknown function. It is thought to be a transmembrane helix. The length of this protein is typically between 150 and 160 amino acids. In humans, it is found in the chromosomal position 17p13.1.


Pssm-ID: 434437  Cd Length: 100  Bit Score: 48.48  E-value: 9.72e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 326432697   19 FFAACGWAQVNDPDPERWVTFYVVCGSVTaLVWAATAAEATGSTAAAL 66
Cdd:pfam15071   1 FFALAAYVQLNDPDPYLWVPIYLLPALLC-LLAALGPAVTGLWRALAV 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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