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Conserved domains on  [gi|325512088|gb|ADZ23255|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Microtus fortis calamorum]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.66e-64

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 195.41  E-value: 1.66e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSSWLTIGILFMSTFMEVSVLFVGDFYESADFMLELNSMGGWVVYDGDELGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 325512088 161 LMGVFIIIEITRGN 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.66e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 195.41  E-value: 1.66e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSSWLTIGILFMSTFMEVSVLFVGDFYESADFMLELNSMGGWVVYDGDELGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 325512088 161 LMGVFIIIEITRGN 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.07e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 40.18  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   17 LGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPEALVSSWLTIGILFMST 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 325512088   97 FMEVSVLFVGDFYESADFMLELNSMGGwvvyDGDELGLmgeggagvaALYSCSAWLMVVSGWTLLMGVFIIIEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.66e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 195.41  E-value: 1.66e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSSWLTIGILFMSTFMEVSVLFVGDFYESADFMLELNSMGGWVVYDGDELGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 325512088 161 LMGVFIIIEITRGN 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.37e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 93.67  E-value: 1.37e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVS-SWLTIGILFMSTFMEVSVLFVGDFYEsadfmlelnsmGGWV-VYDGDELGLMGEGGAGVAALYSCSAWLMVVSGW 158
Cdd:MTH00138  81 SWGSwSVLGYVVGYLVGVVLAAGLFWGGWYE-----------GSWVvVDELKEFSVLRGDVGGVALMYSSGGGMLVICAW 149

                        170
                 ....*....|....*
gi 325512088 159 TLLMGVFIIIEITRG 173
Cdd:MTH00138 150 VLLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 3.89e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 87.21  E-value: 3.89e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSSWLTIGILFMSTFMEVSVLFVGDFYesadfmlelnSMGGWVVYDGDELGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNF----------SLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                        170
                 ....*....|...
gi 325512088 161 LMGVFIIIEITRG 173
Cdd:MTH00065 151 LLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 1.74e-16

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 72.47  E-value: 1.74e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSSWLTIGILFMSTFMEVSVLFVGDFYESADFmlelnsmgGWVVYDGDELGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGV--------GVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                        170
                 ....*....|...
gi 325512088 161 LMGVFIIIEITRG 173
Cdd:MTH00115 153 LLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 1.34e-09

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 54.22  E-value: 1.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   1 MTELIYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  81 ALVSswltiGILFMSTFMEVSVLFVGDFYESADFMlelnsMGGWVVYDgdelGLMGEGGAGVAALYSCSAWLMVVSGWTL 160
Cdd:MTH00214  81 SWGG-----WSVLLFFLFYLLGLGFVGFYFYGGWE-----MLSWMGVD----EANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                        170
                 ....*....|...
gi 325512088 161 LMGVFIIIEITRG 173
Cdd:MTH00214 147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-174 1.54e-09

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 53.76  E-value: 1.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   5 IYLLSSAIVLGCLGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPeaLVS 84
Cdd:MTH00045   3 FYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP--SVS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088  85 SWLTIGILFMSTFMEVSVLFvgdfyesadfmlelNSMGGWVVYDGDELGLMGEGGAGVaaLYSCSAWLMVVSGWTLLMGV 164
Cdd:MTH00045  81 NLGEVLVLSLLLSLWVFISF--------------DNFLELSNNNWSLVSLSDLVGSSE--LYNSGGLYLLLGGFILLVAL 144

                        170
                 ....*....|
gi 325512088 165 FIIIEITRGN 174
Cdd:MTH00045 145 VVALVISFGH 154
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-123 6.80e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 41.14  E-value: 6.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   4 LIYLLSSAIVLGCLgTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSaENYPEALV 83
Cdd:MTH00212   3 LSLLLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS-PNEHLFFK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 325512088  84 SSWLTIGILFMSTFMEVSVLFVGDFYESADFMLELNSMGG 123
Cdd:MTH00212  81 KYFKGFGMILISLNLYLLLMTLGSSNFSPMLNLKLELNVS 120
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.07e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 40.18  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325512088   17 LGTSLKPSPIYGGLCLIVSGCSGCLAVLGLGGSFLGLMVFLIYLGGMLVVFGYTTAMSAENYPEALVSSWLTIGILFMST 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 325512088   97 FMEVSVLFVGDFYESADFMLELNSMGGwvvyDGDELGLmgeggagvaALYSCSAWLMVVSGWTLLMGVFIIIEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGE---------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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