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Conserved domains on  [gi|325343|gb|AAA43801|]
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nonstructural protein 1, partial [Influenza C virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Flu_C_NS2 super family cl46498
Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven ...
 58-219 6.32e-97

Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1 pfam03506 as well as the NS2 protein. The NS2 protein is only about 60 amino acids in length and of unknown function.


The actual alignment was detected with superfamily member pfam03506:

Pssm-ID: 480838  Cd Length: 162  Bit Score: 281.64  E-value: 6.32e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343      58 GELLFNGTILQAESPTMTPVSVEMKGKKLPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNC 137
Cdd:pfam03506   1 GEDKFNGSILLMAFPAMKMAEREEDGDKCPEDFAEKMIAPIGANLITESPCAPNFDEDAIEAGELHFNGAILQKEMNCMC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343     138 FQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGCLIARQVAGIETGIRKCFRCIKSGFVMATDEISLTILRSIKSGAQLDP 217
Cdd:pfam03506  81 FARTEMCGKKFPIDFAPSAFALICQNPIKICGCIIAFDGAGIEAGIRHCFGAIKSGFMMANCEIRLIICHPIKSGAQLDP 160


                  ..
gi 325343     218 YW 219
Cdd:pfam03506 161 AF 162
Flu_C_NS2 pfam03555
Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven ...
 1-57 7.92e-35

Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1 pfam03506 as well as the NS2 protein. The NS2 protein is only about 60 amino acids in length and of unknown function.


:

Pssm-ID: 281544  Cd Length: 57  Bit Score: 120.00  E-value: 7.92e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 325343       1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKD 57
Cdd:pfam03555   1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLKTESSFAPRTWEDAIKD 57
 
Name Accession Description Interval E-value
Flu_C_NS1 pfam03506
Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven ...
 58-219 6.32e-97

Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1. This protein contains 6 conserved cysteines that may be functionally important, perhaps binding to a metal ion.


Pssm-ID: 460949  Cd Length: 162  Bit Score: 281.64  E-value: 6.32e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343      58 GELLFNGTILQAESPTMTPVSVEMKGKKLPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNC 137
Cdd:pfam03506   1 GEDKFNGSILLMAFPAMKMAEREEDGDKCPEDFAEKMIAPIGANLITESPCAPNFDEDAIEAGELHFNGAILQKEMNCMC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343     138 FQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGCLIARQVAGIETGIRKCFRCIKSGFVMATDEISLTILRSIKSGAQLDP 217
Cdd:pfam03506  81 FARTEMCGKKFPIDFAPSAFALICQNPIKICGCIIAFDGAGIEAGIRHCFGAIKSGFMMANCEIRLIICHPIKSGAQLDP 160


                  ..
gi 325343     218 YW 219
Cdd:pfam03506 161 AF 162
Flu_C_NS2 pfam03555
Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven ...
 1-57 7.92e-35

Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1 pfam03506 as well as the NS2 protein. The NS2 protein is only about 60 amino acids in length and of unknown function.


Pssm-ID: 281544  Cd Length: 57  Bit Score: 120.00  E-value: 7.92e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 325343       1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKD 57
Cdd:pfam03555   1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLKTESSFAPRTWEDAIKD 57
 
Name Accession Description Interval E-value
Flu_C_NS1 pfam03506
Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven ...
 58-219 6.32e-97

Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1. This protein contains 6 conserved cysteines that may be functionally important, perhaps binding to a metal ion.


Pssm-ID: 460949  Cd Length: 162  Bit Score: 281.64  E-value: 6.32e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343      58 GELLFNGTILQAESPTMTPVSVEMKGKKLPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNC 137
Cdd:pfam03506   1 GEDKFNGSILLMAFPAMKMAEREEDGDKCPEDFAEKMIAPIGANLITESPCAPNFDEDAIEAGELHFNGAILQKEMNCMC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343     138 FQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGCLIARQVAGIETGIRKCFRCIKSGFVMATDEISLTILRSIKSGAQLDP 217
Cdd:pfam03506  81 FARTEMCGKKFPIDFAPSAFALICQNPIKICGCIIAFDGAGIEAGIRHCFGAIKSGFMMANCEIRLIICHPIKSGAQLDP 160


                  ..
gi 325343     218 YW 219
Cdd:pfam03506 161 AF 162
Flu_C_NS1 pfam03506
Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven ...
 1-157 5.77e-93

Influenza C non-structural protein (NS1); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1. This protein contains 6 conserved cysteines that may be functionally important, perhaps binding to a metal ion.


Pssm-ID: 460949  Cd Length: 162  Bit Score: 271.62  E-value: 5.77e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325343       1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKDGELLFNGTILQAESPTMTPVSVE 80
Cdd:pfam03506   6 NGSILLMAFPAMKMAEREEDGDKCPEDFAEKMIAPIGANLITESPCAPNFDEDAIEAGELHFNGAILQKEMNCMCFARTE 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 325343      81 MKGKKLPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNCFQRTIWCHPNPSRMRLSYAF 157
Cdd:pfam03506  86 MCGKKFPIDFAPSAFALICQNPIKICGCIIAFDGAGIEAGIRHCFGAIKSGFMMANCEIRLIICHPIKSGAQLDPAF 162
Flu_C_NS2 pfam03555
Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven ...
 1-57 7.92e-35

Influenza C non-structural protein (NS2); The influenza C virus genome consists of seven single-stranded RNA segments. The shortest RNA segment encodes a 286 amino acid non-structural protein NS1 pfam03506 as well as the NS2 protein. The NS2 protein is only about 60 amino acids in length and of unknown function.


Pssm-ID: 281544  Cd Length: 57  Bit Score: 120.00  E-value: 7.92e-35
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 325343       1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKD 57
Cdd:pfam03555   1 VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLKTESSFAPRTWEDAIKD 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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