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Conserved domains on  [gi|325084226|gb|EGC37659|]
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hypothetical protein DICPUDRAFT_149749 [Dictyostelium purpureum]

Protein Classification

eukaryotic translation initiation factor 4E( domain architecture ID 10483299)

eukaryotic translation initiation factor 4E (EIF4E) recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of secondary structures of mRNAs

CATH:  3.30.760.10
Gene Ontology:  GO:0016281|GO:0000340|GO:0003723|GO:0003743
PubMed:  30636602|31074051
SCOP:  4001578

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IF4E pfam01652
Eukaryotic initiation factor 4E;
74-227 6.99e-34

Eukaryotic initiation factor 4E;


:

Pssm-ID: 460281  Cd Length: 158  Bit Score: 127.26  E-value: 6.99e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226   74 KWILWYDTKKAINTtttesdgEYLQNVEKVGTFNTLKELKNLWDSLKTP--LEVIGNISIFKEGIEPAWEDSKNKDGGKI 151
Cdd:pfam01652   5 TWTLWYDTKPDKSK-------SYEDNLKKIGTFDTVEDFWSLYNHIKPPseLPPGSDYHLFKEGIKPMWEDPANKNGGKW 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 325084226  152 SVNyLKDNGDFSKVfnaWFTLFTTIVYTTFENY-EQSNGIVLSIRGWGASISLWNGSAE-QDKVQSIKESFHNILSIK 227
Cdd:pfam01652  78 IIR-LKKKGLLDRL---WEDLLLALIGEQFDEDsDEICGAVVSVRKKEDKISIWTRDASdEEAVLKIGKKLKEVLGLP 151
rne super family cl35953
ribonuclease E; Reviewed
 523-650 8.45e-06

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 49.65  E-value: 8.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  523 PEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKVEqqpiETQPESFSKVAKKdksyknknQPQPVssswSAQGLSIAELI 602
Cdd:PRK10811  879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVE----TTHPEVIAAPVTE--------QPQVI----TESDVAVAQEV 942

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 325084226  603 AKQPEPVVSSTPTPSVVEQISATTTVNIVKVETAPSAPSAPSTTPEPV 650
Cdd:PRK10811  943 AEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE 990
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 673-795 5.31e-03

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 673 TDEWKSVEKKTKtaKKISNDKEkkENITNNKGPQdnllirnlivEEPLEYLSPVKQPQKKQSKESSKEQPKSKEQPKEQS 752
Cdd:PTZ00449 482 TQEIKKLIKKSK--KKLAPIEE--EDSDKHDEPP----------EGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGG 547

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 325084226 753 KPKEQPKETNTVKKTSKKQTEVTKTTTSNNKPNNKSVTQNTKD 795
Cdd:PTZ00449 548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKD 590
 
Name Accession Description Interval E-value
IF4E pfam01652
Eukaryotic initiation factor 4E;
74-227 6.99e-34

Eukaryotic initiation factor 4E;


Pssm-ID: 460281  Cd Length: 158  Bit Score: 127.26  E-value: 6.99e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226   74 KWILWYDTKKAINTtttesdgEYLQNVEKVGTFNTLKELKNLWDSLKTP--LEVIGNISIFKEGIEPAWEDSKNKDGGKI 151
Cdd:pfam01652   5 TWTLWYDTKPDKSK-------SYEDNLKKIGTFDTVEDFWSLYNHIKPPseLPPGSDYHLFKEGIKPMWEDPANKNGGKW 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 325084226  152 SVNyLKDNGDFSKVfnaWFTLFTTIVYTTFENY-EQSNGIVLSIRGWGASISLWNGSAE-QDKVQSIKESFHNILSIK 227
Cdd:pfam01652  78 IIR-LKKKGLLDRL---WEDLLLALIGEQFDEDsDEICGAVVSVRKKEDKISIWTRDASdEEAVLKIGKKLKEVLGLP 151
CDC33 COG5053
Translation initiation factor 4E (eIF-4E) [Translation, ribosomal structure and biogenesis];
63-245 1.75e-14

Translation initiation factor 4E (eIF-4E) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227386  Cd Length: 217  Bit Score: 73.39  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  63 DSKNLEETLP--EKWILWYDTKkaiNTTTTESDGEYLQNVekvGTFNTLKELKNLWDSLKTP--LEVIGNISIFKEGIEP 138
Cdd:COG5053   29 DSAHFMNKHPlaFHWTLWFLKP---PEDGLESWSDLLKSI---ITFETVEEFWYILHNISDAsrLPRKSDYNVFREGIRP 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 139 AWEDSKNKDGGKISVNYLKDNGDfsKVFNAWFTLFTTIVYTTFENYEQS-NGIVLSIRGWGASISLWNGSAE-QDKVQSI 216
Cdd:COG5053  103 EWEDEANMNGGKWSFQLKGKGCD--RLDELWLRTLLAAIGETLDPTGSEiGGVVGNMRKGFYKLAIWTRNCNnKDVLGAI 180

                        170       180       190
                 ....*....|....*....|....*....|..
gi 325084226 217 KESFHNILSIKYS---KYSVHKAAILFKNNKK 245
Cdd:COG5053  181 GNEFKQVLELSDVetlEYKAHESSKLGSYHAK 212
PTZ00040 PTZ00040
translation initiation factor E4; Provisional
 66-218 1.54e-12

translation initiation factor E4; Provisional


Pssm-ID: 240238  Cd Length: 233  Bit Score: 67.91  E-value: 1.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  66 NLEETLP--EKWILWydtkKAINTTTTESDGEYLQNVEKVGTFNTLKELKNLWDSLKTPLE-----------------VI 126
Cdd:PTZ00040  33 PLSTPLPlsYKWVIW----EQVVKETIRKSNDYKDYTKPLASFDSVQKFWQLWFNIPQPSElltgkrmiressdgsehVV 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 127 GNISIFKEGIEPAWEDSKNKDGGKISVNYLKDNGDFSKVFNAWFTLFTTIVYTTFENYEQSNGI----VLSIRGWGASIS 202
Cdd:PTZ00040 109 DAVMIFKDGIQPMWEDPMNATGGHFEYRFWPTDVSPGQIDEYWNNLVLALIGSSLEHSSLINGIrlvdKLSGRFGVIRIE 188

                        170
                 ....*....|....*...
gi 325084226 203 LW--NGSAEQDKVQSIKE 218
Cdd:PTZ00040 189 IWftNLGDQSDRNQLMKE 206
rne PRK10811
ribonuclease E; Reviewed
 523-650 8.45e-06

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 49.65  E-value: 8.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  523 PEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKVEqqpiETQPESFSKVAKKdksyknknQPQPVssswSAQGLSIAELI 602
Cdd:PRK10811  879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVE----TTHPEVIAAPVTE--------QPQVI----TESDVAVAQEV 942

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 325084226  603 AKQPEPVVSSTPTPSVVEQISATTTVNIVKVETAPSAPSAPSTTPEPV 650
Cdd:PRK10811  943 AEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE 990
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 673-795 5.31e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 673 TDEWKSVEKKTKtaKKISNDKEkkENITNNKGPQdnllirnlivEEPLEYLSPVKQPQKKQSKESSKEQPKSKEQPKEQS 752
Cdd:PTZ00449 482 TQEIKKLIKKSK--KKLAPIEE--EDSDKHDEPP----------EGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGG 547

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 325084226 753 KPKEQPKETNTVKKTSKKQTEVTKTTTSNNKPNNKSVTQNTKD 795
Cdd:PTZ00449 548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKD 590
Stm1_N pfam09598
Stm1; This region is found at the N terminal of the Stm1 protein. Stm1 is a G4 quadraplex and ...
 521-556 7.46e-03

Stm1; This region is found at the N terminal of the Stm1 protein. Stm1 is a G4 quadraplex and purine motif triplex nucleic acid-binding protein. It has been implicated in many biological processes including apoptosis and telomere biosynthesis. Stm1 is known to interact with CDC13, and is known to associate with ribosomes and nuclear telomere cap complexes.


Pssm-ID: 430706  Cd Length: 64  Bit Score: 35.78  E-value: 7.46e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 325084226  521 EDPEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKV 556
Cdd:pfam09598  16 EDPSQREPAPPTKAVDKPTARTAKRPAKPEPPAQAV 51
 
Name Accession Description Interval E-value
IF4E pfam01652
Eukaryotic initiation factor 4E;
74-227 6.99e-34

Eukaryotic initiation factor 4E;


Pssm-ID: 460281  Cd Length: 158  Bit Score: 127.26  E-value: 6.99e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226   74 KWILWYDTKKAINTtttesdgEYLQNVEKVGTFNTLKELKNLWDSLKTP--LEVIGNISIFKEGIEPAWEDSKNKDGGKI 151
Cdd:pfam01652   5 TWTLWYDTKPDKSK-------SYEDNLKKIGTFDTVEDFWSLYNHIKPPseLPPGSDYHLFKEGIKPMWEDPANKNGGKW 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 325084226  152 SVNyLKDNGDFSKVfnaWFTLFTTIVYTTFENY-EQSNGIVLSIRGWGASISLWNGSAE-QDKVQSIKESFHNILSIK 227
Cdd:pfam01652  78 IIR-LKKKGLLDRL---WEDLLLALIGEQFDEDsDEICGAVVSVRKKEDKISIWTRDASdEEAVLKIGKKLKEVLGLP 151
CDC33 COG5053
Translation initiation factor 4E (eIF-4E) [Translation, ribosomal structure and biogenesis];
63-245 1.75e-14

Translation initiation factor 4E (eIF-4E) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227386  Cd Length: 217  Bit Score: 73.39  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  63 DSKNLEETLP--EKWILWYDTKkaiNTTTTESDGEYLQNVekvGTFNTLKELKNLWDSLKTP--LEVIGNISIFKEGIEP 138
Cdd:COG5053   29 DSAHFMNKHPlaFHWTLWFLKP---PEDGLESWSDLLKSI---ITFETVEEFWYILHNISDAsrLPRKSDYNVFREGIRP 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 139 AWEDSKNKDGGKISVNYLKDNGDfsKVFNAWFTLFTTIVYTTFENYEQS-NGIVLSIRGWGASISLWNGSAE-QDKVQSI 216
Cdd:COG5053  103 EWEDEANMNGGKWSFQLKGKGCD--RLDELWLRTLLAAIGETLDPTGSEiGGVVGNMRKGFYKLAIWTRNCNnKDVLGAI 180

                        170       180       190
                 ....*....|....*....|....*....|..
gi 325084226 217 KESFHNILSIKYS---KYSVHKAAILFKNNKK 245
Cdd:COG5053  181 GNEFKQVLELSDVetlEYKAHESSKLGSYHAK 212
PTZ00040 PTZ00040
translation initiation factor E4; Provisional
 66-218 1.54e-12

translation initiation factor E4; Provisional


Pssm-ID: 240238  Cd Length: 233  Bit Score: 67.91  E-value: 1.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  66 NLEETLP--EKWILWydtkKAINTTTTESDGEYLQNVEKVGTFNTLKELKNLWDSLKTPLE-----------------VI 126
Cdd:PTZ00040  33 PLSTPLPlsYKWVIW----EQVVKETIRKSNDYKDYTKPLASFDSVQKFWQLWFNIPQPSElltgkrmiressdgsehVV 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 127 GNISIFKEGIEPAWEDSKNKDGGKISVNYLKDNGDFSKVFNAWFTLFTTIVYTTFENYEQSNGI----VLSIRGWGASIS 202
Cdd:PTZ00040 109 DAVMIFKDGIQPMWEDPMNATGGHFEYRFWPTDVSPGQIDEYWNNLVLALIGSSLEHSSLINGIrlvdKLSGRFGVIRIE 188

                        170
                 ....*....|....*...
gi 325084226 203 LW--NGSAEQDKVQSIKE 218
Cdd:PTZ00040 189 IWftNLGDQSDRNQLMKE 206
rne PRK10811
ribonuclease E; Reviewed
 523-650 8.45e-06

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 49.65  E-value: 8.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226  523 PEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKVEqqpiETQPESFSKVAKKdksyknknQPQPVssswSAQGLSIAELI 602
Cdd:PRK10811  879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVE----TTHPEVIAAPVTE--------QPQVI----TESDVAVAQEV 942

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 325084226  603 AKQPEPVVSSTPTPSVVEQISATTTVNIVKVETAPSAPSAPSTTPEPV 650
Cdd:PRK10811  943 AEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE 990
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 522-676 2.32e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 47.94  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 522 DPEPIAPAPVKK--VEPTPTPAPVKKVEPTPAPAKKVEQQPIETQPESFSKVAKKDKSYKNKnQPQPVSSSWSAQGLSIA 599
Cdd:PRK07994 371 PPQSAAPAASAQatAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRA-QGATKAKKSEPAAASRA 449

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 325084226 600 ELIAKQPEPVVSSTPTPSVVEQISATTTVNIVKVETAPSAPSAPSTTPEPVKSGLLQIKEAKKVEVLEVVKSETDEW 676
Cdd:PRK07994 450 RPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAEAIERDPW 526
PRK10819 PRK10819
transport protein TonB; Provisional
 523-616 1.40e-04

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 44.29  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 523 PEPIAPAPVkkVEPTPTPAPVKKVEPTPAPAKKVEQQPietQPESFSKVAKKDKSYKNKNQPQPVSSSWSAQglsiaeli 602
Cdd:PRK10819  82 PEPPKEAPV--VIPKPEPKPKPKPKPKPKPVKKVEEQP---KREVKPVEPRPASPFENTAPARPTSSTATAA-------- 148

                         90
                 ....*....|....
gi 325084226 603 AKQPEPVVSSTPTP 616
Cdd:PRK10819 149 ASKPVTSVSSGPRA 162
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
504-648 3.33e-04

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 44.21  E-value: 3.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 504 KEVLQKTEVVSSSDSfweDPEPIAPAPVKKVePTPTPAPVKKVEPTPAPAKKVEQQPIETQPES-FSKVAKKdksyknkn 582
Cdd:PRK12727  48 EELVQRALETARSDT---PATAAAPAPAPQA-PTKPAAPVHAPLKLSANANMSQRQRVASAAEDmIAAMALR-------- 115

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 325084226 583 qpQPVSSSWSAQGlsiaeliakqPEPV-VSSTPTPSVVEQISATTtvnivkVETAPSAPSAPSTTPE 648
Cdd:PRK12727 116 --QPVSVPRQAPA----------AAPVrAASIPSPAAQALAHAAA------VRTAPRQEHALSAVPE 164
PRK11633 PRK11633
cell division protein DedD; Provisional
 521-578 4.06e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 42.68  E-value: 4.06e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 325084226 521 EDPEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKVEQQPiETQPESFSKVAKKDKSY 578
Cdd:PRK11633  94 NTPVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPAPKP-EPKPVVEEKAAPTGKAY 150
PRK11633 PRK11633
cell division protein DedD; Provisional
 507-565 5.06e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 42.30  E-value: 5.06e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 325084226 507 LQKTEVVSSSDSFWEDPEPIAPAPVKKVEPtPTPAPVKKVEPTPAPAKKVEQQPIETQP 565
Cdd:PRK11633  85 LDPATVAPPNTPVEPEPAPVEPPKPKPVEK-PKPKPKPQQKVEAPPAPKPEPKPVVEEK 142
PRK11633 PRK11633
cell division protein DedD; Provisional
 527-593 2.48e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 40.37  E-value: 2.48e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 325084226 527 APAPVKKVEPTPTPAPVKKVEPTPAPAKKVEQQPIETQPESFSKVAKKDKSYKNKNQPQPVSSSWSA 593
Cdd:PRK11633  78 GDAAAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPAPKPEPKPVVEEKAA 144
PHA03369 PHA03369
capsid maturational protease; Provisional
 527-760 3.17e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 41.14  E-value: 3.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 527 APAPVKKVEPTPTPAPVKKVEPTPAPAKKVEQQPIETqPESFSKVAKKDKSYKNKNQPQPVSSSwsaqglSIAELIAKQP 606
Cdd:PHA03369 341 LKAHNEILKTASLTAPSRVLAAAAKVAVIAAPQTHTG-PADRQRPQRPDGIPYSVPARSPMTAY------PPVPQFCGDP 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 607 EPVVSSTPTPSvveqisaTTTVNIVKVETAPSAPSAPSTTPEPVKSGLLQIKEAKKVEvlEVVKSETDEWKsvEKKTKTA 686
Cdd:PHA03369 414 GLVSPYNPQSP-------GTSYGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQEHGH--ERKRKRGGELK--EELIETL 482

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 325084226 687 KKISNDKEKKENITNNKGPQDNL-LIRNLIVEEPLEYLSPVKQPQKKQSKESSKEQPKSKEQPKEQSKPKEQPKE 760
Cdd:PHA03369 483 KLVKKLKEEQESLAKELEATAHKsEIKKIAESEFKNAGAKTAAANIEPNCSADAAAPATKRARPETKTELEAVVR 557
PRK10819 PRK10819
transport protein TonB; Provisional
 521-650 3.53e-03

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 40.05  E-value: 3.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 521 EDPEPIAPAPVKKVEPTPTPAPVkkvePTPAPAKKVEQQPIETQPESfskvakkdksyKNKNQPQPVSSswsaqglsiAE 600
Cdd:PRK10819  59 EPPQAVQPPPEPVVEPEPEPEPI----PEPPKEAPVVIPKPEPKPKP-----------KPKPKPKPVKK---------VE 114

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 325084226 601 LIAKQPEPVVSSTPtPSVVEQISATTTVNIVKVETAPSAPSAPSTTPEPV 650
Cdd:PRK10819 115 EQPKREVKPVEPRP-ASPFENTAPARPTSSTATAAASKPVTSVSSGPRAL 163
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 673-795 5.31e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 325084226 673 TDEWKSVEKKTKtaKKISNDKEkkENITNNKGPQdnllirnlivEEPLEYLSPVKQPQKKQSKESSKEQPKSKEQPKEQS 752
Cdd:PTZ00449 482 TQEIKKLIKKSK--KKLAPIEE--EDSDKHDEPP----------EGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGG 547

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 325084226 753 KPKEQPKETNTVKKTSKKQTEVTKTTTSNNKPNNKSVTQNTKD 795
Cdd:PTZ00449 548 KPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKD 590
Stm1_N pfam09598
Stm1; This region is found at the N terminal of the Stm1 protein. Stm1 is a G4 quadraplex and ...
 521-556 7.46e-03

Stm1; This region is found at the N terminal of the Stm1 protein. Stm1 is a G4 quadraplex and purine motif triplex nucleic acid-binding protein. It has been implicated in many biological processes including apoptosis and telomere biosynthesis. Stm1 is known to interact with CDC13, and is known to associate with ribosomes and nuclear telomere cap complexes.


Pssm-ID: 430706  Cd Length: 64  Bit Score: 35.78  E-value: 7.46e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 325084226  521 EDPEPIAPAPVKKVEPTPTPAPVKKVEPTPAPAKKV 556
Cdd:pfam09598  16 EDPSQREPAPPTKAVDKPTARTAKRPAKPEPPAQAV 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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