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Conserved domains on  [gi|324025196|gb|ADY11955|]
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Ferredoxin--NAD(+) reductase [Sphaerochaeta globosa str. Buddy]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441266)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; belongs to the pyridine nucleotide-disulfide oxidoreductase superfamily

CATH:  3.30.390.30
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0000166
PubMed:  38537870
SCOP:  4000121

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-381 9.19e-136

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 394.51  E-value: 9.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGSCAAS 80
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  81 IDKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLgEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAEG 160
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGA-DLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 161 ILDKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVRA 236
Cdd:COG1251  161 LRKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDrvtgVRLADGEELPADLVVVAIGVRP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 237 NIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEGTEMIGGQKaVLALLPNAYLQGETAGTNMAGGEASFTKAVAMN 316
Cdd:COG1251  241 NTELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGRR-VLELVAPAYEQARVAAANLAGGPAAYEGSVPST 319

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196 317 SLSLCGLHLITVGRYEGESHLI----ACKNGYKRLFVKDNHLVGCILSGDAiHRAGIYTSILRNQVDLD 381
Cdd:COG1251  320 KLKVFGVDVASAGDAEGDEEVVvrgdPARGVYKKLVLRDGRLVGAVLVGDT-SDAGALRQLIKNGRPLP 387
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-381 9.19e-136

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 394.51  E-value: 9.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGSCAAS 80
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  81 IDKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLgEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAEG 160
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGA-DLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 161 ILDKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVRA 236
Cdd:COG1251  161 LRKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDrvtgVRLADGEELPADLVVVAIGVRP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 237 NIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEGTEMIGGQKaVLALLPNAYLQGETAGTNMAGGEASFTKAVAMN 316
Cdd:COG1251  241 NTELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGRR-VLELVAPAYEQARVAAANLAGGPAAYEGSVPST 319

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196 317 SLSLCGLHLITVGRYEGESHLI----ACKNGYKRLFVKDNHLVGCILSGDAiHRAGIYTSILRNQVDLD 381
Cdd:COG1251  320 KLKVFGVDVASAGDAEGDEEVVvrgdPARGVYKKLVLRDGRLVGAVLVGDT-SDAGALRQLIKNGRPLP 387
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-380 3.56e-68

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 230.10  E-value: 3.56e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196    4 VMIGNSIASTACIEAIRTLDRES-RITVIGEENHLCYSRPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGSCAASID 82
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNRHMfEITIFGEEPHPNYNRILLSSVLQGEADLDDITLNSKDWYEKHGITLYTGETVIQID 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   83 KASKTVALESGMSIAYDKLLLATGSSPFIPPIKGlGEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAEGIL 162
Cdd:TIGR02374  82 TDQKQVITDAGRTLSYDKLILATGSYPFILPIPG-ADKKGVYVFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  163 DKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLG----DSIRECTANEALLESGHAIGFDLLVIAVGVRANI 238
Cdd:TIGR02374 161 NLGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLEkdtvEIVGATKADRIRFKDGSSLEADLIVMAAGIRPND 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  239 KLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEgtemIGGQkaVLALLPNAYLQGETAGTNMAGGE-ASFTKAVAMNS 317
Cdd:TIGR02374 241 ELAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAE----HNGR--VYGLVAPLYEQAKVLADHICGVEcEEYEGSDLSAK 314

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196  318 LSLCGLHLITVG---RYEGESHLI---ACKNGYKRLFVKDNHLVGCILSGDAIHRAGIYTSILrNQVDL 380
Cdd:TIGR02374 315 LKLLGVDVWSAGdaqETERTTSIKiydEQKGIYKKLVLSDDKLLGAVLFGDTSDYGRLLDMVL-KQADI 382
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-295 6.56e-56

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 186.37  E-value: 6.56e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196    1 MHYVMIGNSIASTACIEAIRTLDResRITVIGEENHLCYSRPLISY-LLQGKTDEN--------RMTYRNQAFYEENKVT 71
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGG--KVTLIEDEGTCPYGGCVLSKaLLGAAEAPEiaslwadlYKRKEEVVKKLNNGIE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   72 VLQGSCAASIDKASKTVALE-----SGMSIAYDKLLLATGSSPFIPPIKGLGEvKNWFTFLTLDEAKRLQSHLRPdSRVL 146
Cdd:pfam07992  79 VLLGTEVVSIDPGAKKVVLEelvdgDGETITYDRLVIATGARPRLPPIPGVEL-NVGFLVRTLDSAEALRLKLLP-KRVV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  147 ILGAGLIGLKCAEGILDKVHSVSVVDMASRVLPsVLDEQCSLLVREHLQSQGLRFYLGDSIRECTAN----EALLESGHA 222
Cdd:pfam07992 157 VVGGGYIGVELAAALAKLGKEVTLIEALDRLLR-AFDEEISAALEKALEKNGVEVRLGTSVKEIIGDgdgvEVILKDGTE 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196  223 IGFDLLVIAVGVRANIKLAKEAGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGTEMiggqkavlaLLPNAYLQG 295
Cdd:pfam07992 236 IDADLVVVAIGRRPNTELLEAAGLELDErgGIVVDEYLRTSVPGIYAAGDCRVGGPE---------LAQNAVAQG 301
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
4-310 4.57e-53

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 181.27  E-value: 4.57e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   4 VMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLL-QGKTDENRMTYRNQAFYEENKVTVLQGSCAASID 82
Cdd:PRK04965   6 VIIGSGFAARQLVKNIRKQDAHIPITLITADSGDEYNKPDLSHVFsQGQRADDLTRQSAGEFAEQFNLRLFPHTWVTDID 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  83 KASKTVaLESGMSIAYDKLLLATGSSPFIPPIKGLGEVknwFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAegiL 162
Cdd:PRK04965  86 AEAQVV-KSQGNQWQYDKLVLATGASAFVPPIPGRELM---LTLNSQQEYRAAETQLRDAQRVLVVGGGLIGTELA---M 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 163 DKVHS---VSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVR 235
Cdd:PRK04965 159 DLCRAgkaVTLVDNAASLLASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDsgirATLDSGRSIEVDAVIAAAGLR 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196 236 ANIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEgtemIGGQkaVLALLPNAYLQGETAGTNMAGGEASFT 310
Cdd:PRK04965 239 PNTALARRAGLAVNRGIVVDSYLQTSAPDIYALGDCAE----INGQ--VLPFLQPIQLSAMALAKNLLGQNTPLK 307
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
1-381 9.19e-136

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 394.51  E-value: 9.19e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGSCAAS 80
Cdd:COG1251    2 MRIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVLAGETDEEDLLLRPADFYEENGIDLRLGTRVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  81 IDKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLgEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAEG 160
Cdd:COG1251   82 IDRAARTVTLADGETLPYDKLVLATGSRPRVPPIPGA-DLPGVFTLRTLDDADALRAALAPGKRVVVIGGGLIGLEAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 161 ILDKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVRA 236
Cdd:COG1251  161 LRKRGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIEGDDrvtgVRLADGEELPADLVVVAIGVRP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 237 NIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEGTEMIGGQKaVLALLPNAYLQGETAGTNMAGGEASFTKAVAMN 316
Cdd:COG1251  241 NTELARAAGLAVDRGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGRR-VLELVAPAYEQARVAAANLAGGPAAYEGSVPST 319

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196 317 SLSLCGLHLITVGRYEGESHLI----ACKNGYKRLFVKDNHLVGCILSGDAiHRAGIYTSILRNQVDLD 381
Cdd:COG1251  320 KLKVFGVDVASAGDAEGDEEVVvrgdPARGVYKKLVLRDGRLVGAVLVGDT-SDAGALRQLIKNGRPLP 387
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 22-329 1.27e-74

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 235.48  E-value: 1.27e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  22 LDRESRITVIGEENHLCYSRPLISY-LLQGKTDENRMTYRNQAFYEENKVTVLQGSCAASIDKASKTVALESGMSIAYDK 100
Cdd:COG0446    2 LGPDAEITVIEKGPHHSYQPCGLPYyVGGGIKDPEDLLVRTPESFERKGIDVRTGTEVTAIDPEAKTVTLRDGETLSYDK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 101 LLLATGSSPFIPPIKGLgEVKNWFTFLTLDEAKRLQSHLRPDS--RVLILGAGLIGLKCAEGILDKVHSVSVVDMASRVL 178
Cdd:COG0446   82 LVLATGARPRPPPIPGL-DLPGVFTLRTLDDADALREALKEFKgkRAVVIGGGPIGLELAEALRKRGLKVTLVERAPRLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 179 PsVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE---ALLESGHAIGFDLLVIAVGVRANIKLAKEAGLQTNR--GIL 253
Cdd:COG0446  161 G-VLDPEMAALLEEELREHGVELRLGETVVAIDGDDkvaVTLTDGEEIPADLVVVAPGVRPNTELAKDAGLALGErgWIK 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 324025196 254 IDEGGRTSEPDMYAAGDCTEGTEMIGGQKAVLALLPNAYLQGETAGTNMAGGEASFtKAVAMNSLSLCGLHLITVG 329
Cdd:COG0446  240 VDETLQTSDPDVYAAGDCAEVPHPVTGKTVYIPLASAANKQGRVAAENILGGPAPF-PGLGTFISKVFDLCIASTG 314
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 4-380 3.56e-68

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 230.10  E-value: 3.56e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196    4 VMIGNSIASTACIEAIRTLDRES-RITVIGEENHLCYSRPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGSCAASID 82
Cdd:TIGR02374   2 VLVGNGMAGHRCIEEVLKLNRHMfEITIFGEEPHPNYNRILLSSVLQGEADLDDITLNSKDWYEKHGITLYTGETVIQID 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   83 KASKTVALESGMSIAYDKLLLATGSSPFIPPIKGlGEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAEGIL 162
Cdd:TIGR02374  82 TDQKQVITDAGRTLSYDKLILATGSYPFILPIPG-ADKKGVYVFRTIEDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  163 DKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLG----DSIRECTANEALLESGHAIGFDLLVIAVGVRANI 238
Cdd:TIGR02374 161 NLGMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLEkdtvEIVGATKADRIRFKDGSSLEADLIVMAAGIRPND 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  239 KLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEgtemIGGQkaVLALLPNAYLQGETAGTNMAGGE-ASFTKAVAMNS 317
Cdd:TIGR02374 241 ELAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAE----HNGR--VYGLVAPLYEQAKVLADHICGVEcEEYEGSDLSAK 314

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196  318 LSLCGLHLITVG---RYEGESHLI---ACKNGYKRLFVKDNHLVGCILSGDAIHRAGIYTSILrNQVDL 380
Cdd:TIGR02374 315 LKLLGVDVWSAGdaqETERTTSIKiydEQKGIYKKLVLSDDKLLGAVLFGDTSDYGRLLDMVL-KQADI 382
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-295 6.56e-56

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 186.37  E-value: 6.56e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196    1 MHYVMIGNSIASTACIEAIRTLDResRITVIGEENHLCYSRPLISY-LLQGKTDEN--------RMTYRNQAFYEENKVT 71
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGG--KVTLIEDEGTCPYGGCVLSKaLLGAAEAPEiaslwadlYKRKEEVVKKLNNGIE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   72 VLQGSCAASIDKASKTVALE-----SGMSIAYDKLLLATGSSPFIPPIKGLGEvKNWFTFLTLDEAKRLQSHLRPdSRVL 146
Cdd:pfam07992  79 VLLGTEVVSIDPGAKKVVLEelvdgDGETITYDRLVIATGARPRLPPIPGVEL-NVGFLVRTLDSAEALRLKLLP-KRVV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  147 ILGAGLIGLKCAEGILDKVHSVSVVDMASRVLPsVLDEQCSLLVREHLQSQGLRFYLGDSIRECTAN----EALLESGHA 222
Cdd:pfam07992 157 VVGGGYIGVELAAALAKLGKEVTLIEALDRLLR-AFDEEISAALEKALEKNGVEVRLGTSVKEIIGDgdgvEVILKDGTE 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196  223 IGFDLLVIAVGVRANIKLAKEAGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGTEMiggqkavlaLLPNAYLQG 295
Cdd:pfam07992 236 IDADLVVVAIGRRPNTELLEAAGLELDErgGIVVDEYLRTSVPGIYAAGDCRVGGPE---------LAQNAVAQG 301
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
4-310 4.57e-53

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 181.27  E-value: 4.57e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   4 VMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLL-QGKTDENRMTYRNQAFYEENKVTVLQGSCAASID 82
Cdd:PRK04965   6 VIIGSGFAARQLVKNIRKQDAHIPITLITADSGDEYNKPDLSHVFsQGQRADDLTRQSAGEFAEQFNLRLFPHTWVTDID 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  83 KASKTVaLESGMSIAYDKLLLATGSSPFIPPIKGLGEVknwFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKCAegiL 162
Cdd:PRK04965  86 AEAQVV-KSQGNQWQYDKLVLATGASAFVPPIPGRELM---LTLNSQQEYRAAETQLRDAQRVLVVGGGLIGTELA---M 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 163 DKVHS---VSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVR 235
Cdd:PRK04965 159 DLCRAgkaVTLVDNAASLLASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDsgirATLDSGRSIEVDAVIAAAGLR 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196 236 ANIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGDCTEgtemIGGQkaVLALLPNAYLQGETAGTNMAGGEASFT 310
Cdd:PRK04965 239 PNTALARRAGLAVNRGIVVDSYLQTSAPDIYALGDCAE----INGQ--VLPFLQPIQLSAMALAKNLLGQNTPLK 307
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 3-270 6.45e-45

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 160.09  E-value: 6.45e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   3 YVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLIS--YLLQgktDENRMTYR-NQAFYEENKVTVLQGSCAA 79
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSksMLLE---DSPQLQQVlPANWWQENNVHLHSGVTIK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  80 SIDKASKTVALESGMSIAYDKLLLATGSS--PFiPPIKGLGEvkNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGLKC 157
Cdd:PRK09754  83 TLGRDTRELVLTNGESWHWDQLFIATGAAarPL-PLLDALGE--RCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLEL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 158 AEGILDKVHSVSVVDMASRVL----PSVLdeQCSLLVREhlQSQGLRFYLGDSIRECTANEAL---LESGHAIGFDLLVI 230
Cdd:PRK09754 160 AASATQRRCKVTVIELAATVMgrnaPPPV--QRYLLQRH--QQAGVRILLNNAIEHVVDGEKVeltLQSGETLQADVVIY 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 324025196 231 AVGVRANIKLAKEAGLQTNRGILIDEGGRTSEPDMYAAGD 270
Cdd:PRK09754 236 GIGISANDQLAREANLDTANGIVIDEACRTCDPAIFAGGD 275
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 1-353 5.55e-43

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 155.97  E-value: 5.55e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLLQGKTDE-NRMTYRNQAFYEENKVTVLQGSCAA 79
Cdd:PRK09564   1 MKIIIIGGTAAGMSAAAKAKRLNKELEITVYEKTDIVSFGACGLPYFVGGFFDDpNTMIARTPEEFIKSGIDVKTEHEVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  80 SIDKASKTVAL-----ESGMSIAYDKLLLATGSSPFIPPIKGLgEVKNWFTFLTLDEAKRLQSHLRPDS--RVLILGAGL 152
Cdd:PRK09564  81 KVDAKNKTITVknlktGSIFNDTYDKLMIATGARPIIPPIKNI-NLENVYTLKSMEDGLALKELLKDEEikNIVIIGAGF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 153 IGLKCAEGILDKVHSVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTAN---EALLESGHAIGFDLLV 229
Cdd:PRK09564 160 IGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLIGEdkvEGVVTDKGEYEADVVI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 230 IAVGVRANIKLAKEAGLQT--NRGILIDEGGRTSEPDMYAAGDCTEGTEMIGGQKAVLALLPNAYLQGETAGTNMAGGEA 307
Cdd:PRK09564 240 VATGVKPNTEFLEDTGLKTlkNGAIIVDEYGETSIENIYAAGDCATIYNIVSNKNVYVPLATTANKLGRMVGENLAGRHV 319

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 324025196 308 SFTKAVAMNSLSLCGLHLITVGRYEGEshliACKNG--YKRLFVKD-NH 353
Cdd:PRK09564 320 SFKGTLGSACIKVLDLEAARTGLTEEE----AKKLGidYKTVFIKDkNH 364
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 1-362 4.30e-39

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 149.50  E-value: 4.30e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIrtLDR----ESRITVIGEENHLCYSR-PLISYLLQGKTDEnrMTYRNQAFYEENKVTVLQG 75
Cdd:PRK14989   4 VRLAIIGNGMVGHRFIEDL--LDKadaaNFDITVFCEEPRIAYDRvHLSSYFSHHTAEE--LSLVREGFYEKHGIKVLVG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  76 SCAASIDKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGlGEVKNWFTFLTLDEAKRLQSHLRPDSRVLILGAGLIGL 155
Cdd:PRK14989  80 ERAITINRQEKVIHSSAGRTVFYDKLIMATGSYPWIPPIKG-SETQDCFVYRTIEDLNAIEACARRSKRGAVVGGGLLGL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 156 KCAeGILDKVH-SVSVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTA------NEALLESGHAIGFDLL 228
Cdd:PRK14989 159 EAA-GALKNLGvETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQegvearKTMRFADGSELEVDFI 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 229 VIAVGVRANIKLAKEAGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGTEMIGGqkavlaLLPNAYLQGETAGTNMAGGE 306
Cdd:PRK14989 238 VFSTGIRPQDKLATQCGLAVAPrgGIVINDSCQTSDPDIYAIGECASWNNRVFG------LVAPGYKMAQVAVDHLLGSE 311

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196 307 ASFTKAVAMNSLSLCGLHLITVGRYEGES-------HLIACKNGYKRLFV-KDN-HLVGCILSGD 362
Cdd:PRK14989 312 NAFEGADLSAKLKLLGVDVGGIGDAHGRTpgarsyvYLDESKEIYKRLIVsEDNkTLLGAVLVGD 376
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 55-307 3.02e-34

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 132.13  E-value: 3.02e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  55 NRMTYRNQAFYEENKVTVLQGScaASIdKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLGEVKnwftFLTLDEAKR 134
Cdd:COG1249   91 DRLRGGVEELLKKNGVDVIRGR--ARF-VDPHTVEVTGGETLTADHIVIATGSRPRVPPIPGLDEVR----VLTSDEALE 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 135 LQShlRPDsRVLILGAGLIGLKCAeGILDKVHS-VSVVDMASRVLPSvLDEQCSLLVREHLQSQGLRFYLGDSIRECTAN 213
Cdd:COG1249  164 LEE--LPK-SLVVIGGGYIGLEFA-QIFARLGSeVTLVERGDRLLPG-EDPEISEALEKALEKEGIDILTGAKVTSVEKT 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 214 E----ALLESG---HAIGFDLLVIAVGVRANIKL--AKEAGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGtemiggqk 282
Cdd:COG1249  239 GdgvtVTLEDGggeEAVEADKVLVATGRRPNTDGlgLEAAGVELDErgGIKVDEYLRTSVPGIYAIGDVTGG-------- 310

                        250       260
                 ....*....|....*....|....*
gi 324025196 283 avLALLPNAYLQGETAGTNMAGGEA 307
Cdd:COG1249  311 --PQLAHVASAEGRVAAENILGKKP 333
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
20-303 3.05e-34

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 131.02  E-value: 3.05e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  20 RTLDRESRITVIGEENHLCYSrPLISYLLQGKTDENRMTYRNQAFYEENKVTVLQGScAASIDKASKTVALESGMSIAYD 99
Cdd:COG1252   22 KKLGGDAEVTLIDPNPYHLFQ-PLLPEVAAGTLSPDDIAIPLRELLRRAGVRFIQGE-VTGIDPEARTVTLADGRTLSYD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 100 KLLLATGSSPFIPPIKGLGEvkNWFTFLTLDEAKRLQSHL---------RPDSRVLILGAGLIG--------------LK 156
Cdd:COG1252  100 YLVIATGSVTNFFGIPGLAE--HALPLKTLEDALALRERLlaaferaerRRLLTIVVVGGGPTGvelagelaellrklLR 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 157 CAEGILDKVHsVSVVDMASRVLPSvLDEQCSLLVREHLQSQGLRFYLGDSIRECTANEALLESGHAIGFDLLVIAVGVRA 236
Cdd:COG1252  178 YPGIDPDKVR-ITLVEAGPRILPG-LGEKLSEAAEKELEKRGVEVHTGTRVTEVDADGVTLEDGEEIPADTVIWAAGVKA 255

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 237 NiKLAKEAGLQTNRG--ILIDEGGRTSE-PDMYAAGDCTEGTEMIGgqKAVLALLPNAYLQGETAGTNMA 303
Cdd:COG1252  256 P-PLLADLGLPTDRRgrVLVDPTLQVPGhPNVFAIGDCAAVPDPDG--KPVPKTAQAAVQQAKVLAKNIA 322
MerA TIGR02053
mercury(II) reductase; This model represents the mercuric reductase found in the mer operon ...
 83-305 8.58e-22

mercury(II) reductase; This model represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH. [Cellular processes, Detoxification]


Pssm-ID: 273944 [Multi-domain]  Cd Length: 463  Bit Score: 96.72  E-value: 8.58e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   83 KASKTVALESGMSIAYDK-LLLATGSSPFIPPIKGLGEVKNWftflTLDEAKRLQshlRPDSRVLILGAGLIGLKCAEGI 161
Cdd:TIGR02053 113 KDPKTVKVDLGREVRGAKrFLIATGARPAIPPIPGLKEAGYL----TSEEALALD---RIPESLAVIGGGAIGVELAQAF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  162 LDKVHSVSVVDMASRVLPSVlDEQCSLLVREHLQSQGLRFYLGDSIRECTANEALL-------ESGHAIGFDLLVIAVGV 234
Cdd:TIGR02053 186 ARLGSEVTILQRSDRLLPRE-EPEISAAVEEALAEEGIEVVTSAQVKAVSVRGGGKiitvekpGGQGEVEADELLVATGR 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196  235 RANIK-LAKE-AGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGtemiggqkavLALLPNAYLQGETAGTNMAGG 305
Cdd:TIGR02053 265 RPNTDgLGLEkAGVKLDErgGILVDETLRTSNPGIYAAGDVTGG----------LQLEYVAAKEGVVAAENALGG 329
PRK13748 PRK13748
putative mercuric reductase; Provisional
 1-336 8.59e-22

putative mercuric reductase; Provisional


Pssm-ID: 184298 [Multi-domain]  Cd Length: 561  Bit Score: 97.53  E-value: 8.59e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACieAIRTLDRESRIT-----VIG---------------EENHLCYSR-------------PLI--S 45
Cdd:PRK13748  99 LHVAVIGSGGAAMAA--ALKAVEQGARVTliergTIGgtcvnvgcvpskimiRAAHIAHLRrespfdggiaatvPTIdrS 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  46 YLL---QGKTDENRmtyrnQAFYE-----ENKVTVLQGScAASIDKASKTVALESGMS--IAYDKLLLATGSSPFIPPIK 115
Cdd:PRK13748 177 RLLaqqQARVDELR-----HAKYEgildgNPAITVLHGE-ARFKDDQTLIVRLNDGGErvVAFDRCLIATGASPAVPPIP 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 116 GLGEVKNWftflTLDEAkrLQSHLRPDsRVLILGAGLIGLKCAEGILDKVHSVSVV---DMASRVLPSVLD------EQC 186
Cdd:PRK13748 251 GLKETPYW----TSTEA--LVSDTIPE-RLAVIGSSVVALELAQAFARLGSKVTILarsTLFFREDPAIGEavtaafRAE 323

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 187 SLLVREHLQSQGLRFylgdsirecTANEALLESGHA-IGFDLLVIAVGVRANI-KLAKEA-GLQTN-RG-ILIDEGGRTS 261
Cdd:PRK13748 324 GIEVLEHTQASQVAH---------VDGEFVLTTGHGeLRADKLLVATGRAPNTrSLALDAaGVTVNaQGaIVIDQGMRTS 394

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196 262 EPDMYAAGDCTEGTEMIGGQKAVlallpnaylqGETAGTNMAGGEASFtKAVAMNSLSLCGLHLITVGRYEGESH 336
Cdd:PRK13748 395 VPHIYAAGDCTDQPQFVYVAAAA----------GTRAAINMTGGDAAL-DLTAMPAVVFTDPQVATVGYSEAEAH 458
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 68-304 3.10e-19

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 89.05  E-value: 3.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  68 NKVTVLQGScAASIDKASKTVALESG-MSIAYDKLLLATGSSPFIPP-IKGLGEVknwftFLTLDEAkrlqshLRPD--- 142
Cdd:PRK06416 105 NKVDIIRGE-AKLVDPNTVRVMTEDGeQTYTAKNIILATGSRPRELPgIEIDGRV-----IWTSDEA------LNLDevp 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 143 SRVLILGAGLIGLKCAegilDKVHS----VSVVDMASRVLPsVLDEQCSLLVREHLQSQGLRFYLGDSIR--ECTAN--E 214
Cdd:PRK06416 173 KSLVVIGGGYIGVEFA----SAYASlgaeVTIVEALPRILP-GEDKEISKLAERALKKRGIKIKTGAKAKkvEQTDDgvT 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 215 ALLESG---HAIGFDLLVIAVGVRANIK---LAkEAGLQTNRG-ILIDEGGRTSEPDMYAAGDCTEGtemiggqkavLAL 287
Cdd:PRK06416 248 VTLEDGgkeETLEADYVLVAVGRRPNTEnlgLE-ELGVKTDRGfIEVDEQLRTNVPNIYAIGDIVGG----------PML 316

                        250
                 ....*....|....*..
gi 324025196 288 LPNAYLQGETAGTNMAG 304
Cdd:PRK06416 317 AHKASAEGIIAAEAIAG 333
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 1-270 6.87e-17

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 82.14  E-value: 6.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   1 MHYVMIGNSIASTACIEAIRTLDRESRITVIGEENHLCYSRPLISYLLqGKTDENR---MTYRNQAFYEENKVTVLQGSC 77
Cdd:PRK13512   2 PKIIVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYYI-GEVVEDRkyaLAYTPEKFYDRKQITVKTYHE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  78 AASIDKASKTVAL-----ESGMSIAYDKLLLATGSSPFIPPIkglgEVKNWFTFLTLDEAKRLQSHLRPDS--RVLILGA 150
Cdd:PRK13512  81 VIAINDERQTVTVlnrktNEQFEESYDKLILSPGASANSLGF----ESDITFTLRNLEDTDAIDQFIKANQvdKALVVGA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 151 GLIGLKCAEGILDKVHSVSVVDMASRVLpSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANEALLESGHAIGFDLLVI 230
Cdd:PRK13512 157 GYISLEVLENLYERGLHPTLIHRSDKIN-KLMDADMNQPILDELDKREIPYRLNEEIDAINGNEVTFKSGKVEHYDMIIE 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 324025196 231 AVGVRANIKLAKEAGLQTNRG--ILIDEGGRTSEPDMYAAGD 270
Cdd:PRK13512 236 GVGTHPNSKFIESSNIKLDDKgfIPVNDKFETNVPNIYAIGD 277
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 66-307 2.73e-16

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 80.22  E-value: 2.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  66 EENKVTVLQGScaASIdKASKTVALEsGMSIAYDKLLLATGSSpfIPPIKGLGEVKNwFTFLTLDEAKRLQShlRPDSrV 145
Cdd:PRK06292 103 KKPKIDKIKGT--ARF-VDPNTVEVN-GERIEAKNIVIATGSR--VPPIPGVWLILG-DRLLTSDDAFELDK--LPKS-L 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 146 LILGAGLIGLKCAE-----GIldkvhSVSVVDMASRVLPSvLDEQCSLLVREHLQSQgLRFYLGDSIRECT-------AN 213
Cdd:PRK06292 173 AVIGGGVIGLELGQalsrlGV-----KVTVFERGDRILPL-EDPEVSKQAQKILSKE-FKIKLGAKVTSVEksgdekvEE 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 214 EALLESGHAIGFDLLVIAVGVRANIKL--AKEAGLQT-NRG-ILIDEGGRTSEPDMYAAGDCTegtemiggqkAVLALLP 289
Cdd:PRK06292 246 LEKGGKTETIEADYVLVATGRRPNTDGlgLENTGIELdERGrPVVDEHTQTSVPGIYAAGDVN----------GKPPLLH 315

                        250
                 ....*....|....*...
gi 324025196 290 NAYLQGETAGTNMAGGEA 307
Cdd:PRK06292 316 EAADEGRIAAENAAGDVA 333
PRK06370 PRK06370
FAD-containing oxidoreductase;
62-271 7.72e-16

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 79.09  E-value: 7.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  62 QAFYEENKVTVLQGScAASIDKasKTVALeSGMSIAYDKLLLATGSSPFIPPIKGLGEVkNWFTFLTLDEAKRLQSHLrp 141
Cdd:PRK06370 102 QWLRGLEGVDVFRGH-ARFESP--NTVRV-GGETLRAKRIFINTGARAAIPPIPGLDEV-GYLTNETIFSLDELPEHL-- 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 142 dsrvLILGAGLIGLKCAE-----GildkvHSVSVVDMASRVLPSVlDEQCSLLVREHLQSQGLRFYL----------GDS 206
Cdd:PRK06370 175 ----VIIGGGYIGLEFAQmfrrfG-----SEVTVIERGPRLLPRE-DEDVAAAVREILEREGIDVRLnaecirverdGDG 244

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 324025196 207 IR---ECTANEallesgHAIGFDLLVIAVGVRANIK---LAKeAGLQTNR--GILIDEGGRTSEPDMYAAGDC 271
Cdd:PRK06370 245 IAvglDCNGGA------PEITGSHILVAVGRVPNTDdlgLEA-AGVETDArgYIKVDDQLRTTNPGIYAAGDC 310
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
62-307 5.40e-15

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 76.35  E-value: 5.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  62 QAFYEENKVTVLQGScAASIDKASKTVALESGMSIAY--DKLLLATGSSPFIPPikglgEVKnwF---------TFLTLD 130
Cdd:PRK05249 101 RGQYERNRVDLIQGR-ARFVDPHTVEVECPDGEVETLtaDKIVIATGSRPYRPP-----DVD--FdhpriydsdSILSLD 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 131 EAKRlqshlrpdsRVLILGAGLIGLKCAE--GILDkvHSVSVVDMASRVLpSVLDEQCSLLVREHLQSQGLRFYLGDSIR 208
Cdd:PRK05249 173 HLPR---------SLIIYGAGVIGCEYASifAALG--VKVTLINTRDRLL-SFLDDEISDALSYHLRDSGVTIRHNEEVE 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 209 ECTANE----ALLESGHAIGFDLLVIAVGVRANI-KLAKE-AGLQTN-RG-ILIDEGGRTSEPDMYAAGDctegteMIGG 280
Cdd:PRK05249 241 KVEGGDdgviVHLKSGKKIKADCLLYANGRTGNTdGLNLEnAGLEADsRGqLKVNENYQTAVPHIYAVGD------VIGF 314

                        250       260
                 ....*....|....*....|....*..
gi 324025196 281 QkavlALLPNAYLQGETAGTNMAGGEA 307
Cdd:PRK05249 315 P----SLASASMDQGRIAAQHAVGEAT 337
PRK07251 PRK07251
FAD-containing oxidoreductase;
4-274 3.44e-14

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 73.63  E-value: 3.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   4 VMIGNSIASTACIEAiRTLdresritVIGEENHLCYSRPLIsyllQGKTDENRMTYRNQAFYEENKVTVLQGSCAASIDK 83
Cdd:PRK07251  37 AMYGGTCINIGCIPT-KTL-------LVAAEKNLSFEQVMA----TKNTVTSRLRGKNYAMLAGSGVDLYDAEAHFVSNK 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  84 ASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLGEVKNWFtfltlDEAKRLQSHLRPdSRVLILGAGLIGLKCAeGILD 163
Cdd:PRK07251 105 VIEVQAGDEKIELTAETIVINTGAVSNVLPIPGLADSKHVY-----DSTGIQSLETLP-ERLGIIGGGNIGLEFA-GLYN 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 164 KVHS-VSVVDMASRVLPSVlDEQCSLLVREHLQSQGLRFYLGDSIREcTANEA----LLESGHAIGFDLLVIAVGVRANI 238
Cdd:PRK07251 178 KLGSkVTVLDAASTILPRE-EPSVAALAKQYMEEDGITFLLNAHTTE-VKNDGdqvlVVTEDETYRFDALLYATGRKPNT 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 324025196 239 klakeAGLQ--------TNRG-ILIDEGGRTSEPDMYAAGDCTEG 274
Cdd:PRK07251 256 -----EPLGlentdielTERGaIKVDDYCQTSVPGVFAVGDVNGG 295
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 144-214 2.44e-10

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 56.44  E-value: 2.44e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 324025196  144 RVLILGAGLIGLKCAEGILDKVHSVSVVDMASRVLPsVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE 214
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRLLP-GFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGNG 70
PRK07846 PRK07846
mycothione reductase; Reviewed
 70-270 3.50e-10

mycothione reductase; Reviewed


Pssm-ID: 181142 [Multi-domain]  Cd Length: 451  Bit Score: 61.51  E-value: 3.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  70 VTVLQGScAASIDkaSKTVALESGMSIAYDKLLLATGSSPFIPPIKGLGEVKnwftFLTLDEAKRLQshlRPDSRVLILG 149
Cdd:PRK07846 104 IDVYRGH-ARFIG--PKTLRTGDGEEITADQVVIAAGSRPVIPPVIADSGVR----YHTSDTIMRLP---ELPESLVIVG 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 150 AGLIGLKCAEgildkVHS-----VSVVDMASRVLPSVLDEQCSLLVRehLQSQGLRFYLGDSIRECTAN----EALLESG 220
Cdd:PRK07846 174 GGFIAAEFAH-----VFSalgvrVTVVNRSGRLLRHLDDDISERFTE--LASKRWDVRLGRNVVGVSQDgsgvTLRLDDG 246

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 324025196 221 HAIGFDLLVIAVGVRANIKL--AKEAGLQTNRG--ILIDEGGRTSEPDMYAAGD 270
Cdd:PRK07846 247 STVEADVLLVATGRVPNGDLldAAAAGVDVDEDgrVVVDEYQRTSAEGVFALGD 300
TGR TIGR01438
thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member ...
 100-274 7.38e-10

thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member of the pyridine nucleotide disulfide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-term arm of the protein is proposed to allow broad substrate specificity.


Pssm-ID: 273624 [Multi-domain]  Cd Length: 484  Bit Score: 60.64  E-value: 7.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  100 KLLLATGSSPFIPPIKGLGEVKnwftfLTLDEAKRLQShlrPDSRVLILGAGLIGLKCAeGILDKVhSVSVVDMASRVLP 179
Cdd:TIGR01438 146 RFLIATGERPRYPGIPGAKELC-----ITSDDLFSLPY---CPGKTLVVGASYVALECA-GFLAGI-GLDVTVMVRSILL 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  180 SVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANEALL-------ESGHAIGFDLLVIAVGVRANI-KLAKE-AGLQTNR 250
Cdd:TIGR01438 216 RGFDQDCANKVGEHMEEHGVKFKRQFVPIKVEQIEAKVlveftdsTNGIEEEYDTVLLAIGRDACTrKLNLEnVGVKINK 295

                         170       180
                  ....*....|....*....|....*..
gi 324025196  251 G---ILIDEGGRTSEPDMYAAGDCTEG 274
Cdd:TIGR01438 296 KtgkIPADEEEQTNVPYIYAVGDILED 322
PRK08010 PRK08010
pyridine nucleotide-disulfide oxidoreductase; Provisional
 60-276 1.01e-09

pyridine nucleotide-disulfide oxidoreductase; Provisional


Pssm-ID: 181196 [Multi-domain]  Cd Length: 441  Bit Score: 60.03  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  60 RNQAFY---EENKVTVLQGScAASIDKASKTVALESG-MSIAYDKLLLATGSSPFIPPIKGLGEVKNWFTFLTLDEAKRL 135
Cdd:PRK08010  79 RNKNFHnlaDMPNIDVIDGQ-AEFINNHSLRVHRPEGnLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKEL 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 136 QSHLRpdsrvlILGAGLIGLKCAEGILDKVHSVSVVDMASRVLPSVlDEQCSLLVREHLQSQGLRFYLGDSIRECTANE- 214
Cdd:PRK08010 158 PGHLG------ILGGGYIGVEFASMFANFGSKVTILEAASLFLPRE-DRDIADNIATILRDQGVDIILNAHVERISHHEn 230

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196 215 -ALLESGHA-IGFDLLVIAVGVR---ANIKLaKEAGLQTNR--GILIDEGGRTSEPDMYAAGDCTEGTE 276
Cdd:PRK08010 231 qVQVHSEHAqLAVDALLIASGRQpatASLHP-ENAGIAVNErgAIVVDKYLHTTADNIWAMGDVTGGLQ 298
PLN02546 PLN02546
glutathione reductase
 101-273 1.04e-09

glutathione reductase


Pssm-ID: 215301 [Multi-domain]  Cd Length: 558  Bit Score: 60.27  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 101 LLLATGSSPFIPPIKGLGEVknwftfLTLDEAKRLQShlRPDsRVLILGAGLIGLKCAeGILDKVHS-VSVVDMASRVLP 179
Cdd:PLN02546 220 ILIAVGGRPFIPDIPGIEHA------IDSDAALDLPS--KPE-KIAIVGGGYIALEFA-GIFNGLKSdVHVFIRQKKVLR 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 180 SvLDEQCSLLVREHLQSQGLRFYLGDSIRECT-ANEALLE----SGHAIGFDLLVIAVGVRANiklAKEAGLQT------ 248
Cdd:PLN02546 290 G-FDEEVRDFVAEQMSLRGIEFHTEESPQAIIkSADGSLSlktnKGTVEGFSHVMFATGRKPN---TKNLGLEEvgvkmd 365

                        170       180
                 ....*....|....*....|....*.
gi 324025196 249 -NRGILIDEGGRTSEPDMYAAGDCTE 273
Cdd:PLN02546 366 kNGAIEVDEYSRTSVPSIWAVGDVTD 391
PTZ00052 PTZ00052
thioredoxin reductase; Provisional
 94-274 3.50e-09

thioredoxin reductase; Provisional


Pssm-ID: 185416 [Multi-domain]  Cd Length: 499  Bit Score: 58.30  E-value: 3.50e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  94 MSIAYDKLLLATGSSPFIP-PIKGLGEVKnwftfLTLDEAKRLQshlRPDSRVLILGAGLIGLKCAeGILDKVHSVSVVD 172
Cdd:PTZ00052 141 ETITAKYILIATGGRPSIPeDVPGAKEYS-----ITSDDIFSLS---KDPGKTLIVGASYIGLETA-GFLNELGFDVTVA 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 173 MASRVLPSvLDEQCSLLVREHLQSQGLRFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVRANIKlakeaGLQT 248
Cdd:PTZ00052 212 VRSIPLRG-FDRQCSEKVVEYMKEQGTLFLEGVVPINIEKMDdkikVLFSDGTTELFDTVLYATGRKPDIK-----GLNL 285

                        170       180       190
                 ....*....|....*....|....*....|....
gi 324025196 249 NR-GILIDEGGR-------TSEPDMYAAGDCTEG 274
Cdd:PTZ00052 286 NAiGVHVNKSNKiiapndcTNIPNIFAVGDVVEG 319
PTZ00058 PTZ00058
glutathione reductase; Provisional
 89-271 5.67e-09

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 58.09  E-value: 5.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  89 ALESGMSIAYDKLLLATGSSPFIPPIKGLGEVKNWFTFLTLDEAKrlqshlrpdsRVLILGAGLIGLKCAeGILDKVHSV 168
Cdd:PTZ00058 194 QLDDGQVIEGKNILIAVGNKPIFPDVKGKEFTISSDDFFKIKEAK----------RIGIAGSGYIAVELI-NVVNRLGAE 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 169 SVVDMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTANEA------LLESGHAIGFDLLVIAVGVRANIKLAK 242
Cdd:PTZ00058 263 SYIFARGNRLLRKFDETIINELENDMKKNNINIITHANVEEIEKVKEknltiyLSDGRKYEHFDYVIYCVGRSPNTEDLN 342

                        170       180       190
                 ....*....|....*....|....*....|..
gi 324025196 243 EAGL--QTNRG-ILIDEGGRTSEPDMYAAGDC 271
Cdd:PTZ00058 343 LKALniKTPKGyIKVDDNQRTSVKHIYAVGDC 374
trypano_reduc TIGR01423
trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of ...
 99-273 1.38e-08

trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of spermidine, is (in its reduced form) an important antioxidant found in trypanosomatids (Crithidia, Leishmania, Trypanosoma). This model describes trypanothione reductase, a possible antitrypanosomal drug target closely related to some forms of glutathione reductase.


Pssm-ID: 200098 [Multi-domain]  Cd Length: 486  Bit Score: 56.52  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196   99 DKLLLATGSSPFIPPIKGLGEVknwftfLTLDEAKRLQshlRPDSRVLILGAGLIGLKCAeGILDKVHSVS-VVDMASRV 177
Cdd:TIGR01423 153 EHILLATGSWPQMLGIPGIEHC------ISSNEAFYLD---EPPRRVLTVGGGFISVEFA-GIFNAYKPRGgKVTLCYRN 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  178 LPSV--LDEQCSLLVREHLQSQGLRFYLGDSIRECTAN-----EALLESGHAIGFDLLVIAVG--VRANIKLAKEAG--L 246
Cdd:TIGR01423 223 NMILrgFDSTLRKELTKQLRANGINIMTNENPAKVTLNadgskHVTFESGKTLDVDVVMMAIGrvPRTQTLQLDKVGveL 302

                         170       180
                  ....*....|....*....|....*..
gi 324025196  247 QTNRGILIDEGGRTSEPDMYAAGDCTE 273
Cdd:TIGR01423 303 TKKGAIQVDEFSRTNVPNIYAIGDVTD 329
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 68-282 2.28e-08

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 55.70  E-value: 2.28e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  68 NKVTVL--QGSCAASIDKASKT-VALESGMSIAYDKLLLATGSSPFIPPIKGLGEVknwftfLTLDEAKRLQSHLRPdSR 144
Cdd:PRK06327 113 NKITVLkgRGSFVGKTDAGYEIkVTGEDETVITAKHVIIATGSEPRHLPGVPFDNK------IILDNTGALNFTEVP-KK 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 145 VLILGAGLIGLKC--------AEgildkvhsVSVVDMASRVLPSVlDEQCSLLVREHLQSQGLRFYLGDSIRECTA---- 212
Cdd:PRK06327 186 LAVIGAGVIGLELgsvwrrlgAE--------VTILEALPAFLAAA-DEQVAKEAAKAFTKQGLDIHLGVKIGEIKTggkg 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 213 -----NEALLESgHAIGFDLLVIAVGVRANIK--LAKEAGLQTN-RG-ILIDEGGRTSEPDMYAAGDCTEG--------- 274
Cdd:PRK06327 257 vsvayTDADGEA-QTLEVDKLIVSIGRVPNTDglGLEAVGLKLDeRGfIPVDDHCRTNVPNVYAIGDVVRGpmlahkaee 335

                        250
                 ....*....|...
gi 324025196 275 -----TEMIGGQK 282
Cdd:PRK06327 336 egvavAERIAGQK 348
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 18-349 1.48e-07

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 53.23  E-value: 1.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  18 AIRTLDRE-SRITVIGEENHLCYSrPLISYLLQGkTDENRMT---YRNQAFYEENKVtvLQGScAASIDKASKTV----- 88
Cdd:PTZ00318  25 FVRNLDPKkYNITVISPRNHMLFT-PLLPQTTTG-TLEFRSIcepVRPALAKLPNRY--LRAV-VYDVDFEEKRVkcgvv 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  89 -----ALESGMSIAYDKLLLATGSSPFIPPIKGLGEvkNWFTFLTLDEAKRLQSHL--------RPDSRV---------L 146
Cdd:PTZ00318 100 sksnnANVNTFSVPYDKLVVAHGARPNTFNIPGVEE--RAFFLKEVNHARGIRKRIvqcierasLPTTSVeerkrllhfV 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 147 ILGAGLIGLKCAEGILDKVHsvsvvDMASRVLPSVLDEqCSLLVRE-----------HLQSQGLRFY--LGDSIR----- 208
Cdd:PTZ00318 178 VVGGGPTGVEFAAELADFFR-----DDVRNLNPELVEE-CKVTVLEagsevlgsfdqALRKYGQRRLrrLGVDIRtktav 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 209 -ECTANEALLESGHAIGFDLLVIAVGVrANIKLAKEAGL-QTNRG-ILIDEGGRTSE-PDMYAAGDCTEGTEMIGGQKAV 284
Cdd:PTZ00318 252 kEVLDKEVVLKDGEVIPTGLVVWSTGV-GPGPLTKQLKVdKTSRGrISVDDHLRVKPiPNVFALGDCAANEERPLPTLAQ 330

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 324025196 285 LALLPNAYLQGETAGtNMAGGEasFTKAVAMNSLSLcglhLITVGRYEGESHLIACK-NGYKRLFV 349
Cdd:PTZ00318 331 VASQQGVYLAKEFNN-ELKGKP--MSKPFVYRSLGS----LAYLGNYSAIVQLGAFDlSGFKALLF 389
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
82-275 3.39e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 51.66  E-value: 3.39e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  82 DKASKTVALESGMSIAYDKLLLATGSSPFIPPIKGLGE--VKNWFTFLTLDEAkrlqshLRPDSRVLILGAGLIGLKCA- 158
Cdd:COG0492   85 DDGPFRVTTDDGTEYEAKAVIIATGAGPRKLGLPGEEEfeGRGVSYCATCDGF------FFRGKDVVVVGGGDSALEEAl 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 159 --EGILDKVHSVSVVD--MASRVLpsvldeqcsllVREHLQSQGLRFYLGDSIRECTANEAL----LESGHA-----IGF 225
Cdd:COG0492  159 ylTKFASKVTLIHRRDelRASKIL-----------VERLRANPKIEVLWNTEVTEIEGDGRVegvtLKNVKTgeekeLEV 227

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 324025196 226 DLLVIAVGVRANIKLAKEAGLQTNRG--ILIDEGGRTSEPDMYAAGDCTEGT 275
Cdd:COG0492  228 DGVFVAIGLKPNTELLKGLGLELDEDgyIVVDEDMETSVPGVFAAGDVRDYK 279
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
144-237 2.51e-06

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 49.36  E-value: 2.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 144 RVLILGAGLIGLKCA---EGILDKVHSVSVVD-------------MASRVLPSvldEQCSLLVREHLQSQGLRFYLG--D 205
Cdd:COG1252    3 RIVIVGGGFAGLEAArrlRKKLGGDAEVTLIDpnpyhlfqpllpeVAAGTLSP---DDIAIPLRELLRRAGVRFIQGevT 79

                         90       100       110
                 ....*....|....*....|....*....|...
gi 324025196 206 SI-REctANEALLESGHAIGFDLLVIAVGVRAN 237
Cdd:COG1252   80 GIdPE--ARTVTLADGRTLSYDYLVIATGSVTN 110
PLN02507 PLN02507
glutathione reductase
 47-308 2.54e-06

glutathione reductase


Pssm-ID: 215281 [Multi-domain]  Cd Length: 499  Bit Score: 49.43  E-value: 2.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  47 LLQGKTDE-NRMTYRNQAFYEENKVTVLQGScAASIDKASKTVALESGMSIAY--DKLLLATGSSPFIPPIKG--LGevk 121
Cdd:PLN02507 115 LLQKKTDEiLRLNGIYKRLLANAGVKLYEGE-GKIVGPNEVEVTQLDGTKLRYtaKHILIATGSRAQRPNIPGkeLA--- 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 122 nwftfLTLDEAKRLQSHLRpdsRVLILGAGLIGLKCAeGILDKVHSVsvVDMASRV-LP-SVLDEQCSLLVREHLQSQGL 199
Cdd:PLN02507 191 -----ITSDEALSLEELPK---RAVVLGGGYIAVEFA-SIWRGMGAT--VDLFFRKeLPlRGFDDEMRAVVARNLEGRGI 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 200 RFYLGDSIRECTANE----ALLESGHAIGFDLLVIAVGVRANIK-LAKEA-GLQTNR--GILIDEGGRTSEPDMYAAGDC 271
Cdd:PLN02507 260 NLHPRTNLTQLTKTEggikVITDHGEEFVADVVLFATGRAPNTKrLNLEAvGVELDKagAVKVDEYSRTNIPSIWAIGDV 339

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 324025196 272 TEGtemiggqkavLALLPNAYLQGETAGTNMAGGEAS 308
Cdd:PLN02507 340 TNR----------INLTPVALMEGTCFAKTVFGGQPT 366
PRK07845 PRK07845
flavoprotein disulfide reductase; Reviewed
 99-298 2.07e-04

flavoprotein disulfide reductase; Reviewed


Pssm-ID: 236112 [Multi-domain]  Cd Length: 466  Bit Score: 43.31  E-value: 2.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  99 DKLLLATGSSPFI-PPIKGLGE-VKNWFTFLTLDEakrLQSHLrpdsrvLILGAGLIGlkcAE--------GIldKVHSV 168
Cdd:PRK07845 141 DVVLIATGASPRIlPTAEPDGErILTWRQLYDLDE---LPEHL------IVVGSGVTG---AEfasaytelGV--KVTLV 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 169 SVVDmasRVLPSVlDEQCSLLVREHLQSQGLRF----------YLGDSIRECTANEALLESGHAIgfdllvIAVGV---R 235
Cdd:PRK07845 207 SSRD---RVLPGE-DADAAEVLEEVFARRGMTVlkrsraesveRTGDGVVVTLTDGRTVEGSHAL------MAVGSvpnT 276

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324025196 236 ANIKLAkEAGLQTNRG--ILIDEGGRTSEPDMYAAGDCTegtemiggqkAVLALLPNAYLQGETA 298
Cdd:PRK07845 277 AGLGLE-EAGVELTPSghITVDRVSRTSVPGIYAAGDCT----------GVLPLASVAAMQGRIA 330
PTZ00153 PTZ00153
lipoamide dehydrogenase; Provisional
 92-278 2.30e-04

lipoamide dehydrogenase; Provisional


Pssm-ID: 173442 [Multi-domain]  Cd Length: 659  Bit Score: 43.36  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196  92 SGMSIAYDKLLLATGSSPFIPPikglGEVKNWFTFLTLDEAKRLQSHlrpDSRVLILGAGLIGLKCAEGILDKVHSVSVV 171
Cdd:PTZ00153 269 SGKEFKVKNIIIATGSTPNIPD----NIEVDQKSVFTSDTAVKLEGL---QNYMGIVGMGIIGLEFMDIYTALGSEVVSF 341

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 172 DMASRVLPSVLDEQCSLLVREHLQSQGLRFYLGDSIRECTA--NEALLESGHA-------------------IGFDLLVI 230
Cdd:PTZ00153 342 EYSPQLLPLLDADVAKYFERVFLKSKPVRVHLNTLIEYVRAgkGNQPVIIGHSerqtgesdgpkknmndikeTYVDSCLV 421

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 324025196 231 AVGVRANIK-LAKEA-GLQTNRG-ILIDEGGRTSEPD------MYAAGDcTEGTEMI 278
Cdd:PTZ00153 422 ATGRKPNTNnLGLDKlKIQMKRGfVSVDEHLRVLREDqevydnIFCIGD-ANGKQML 477
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 226-298 3.85e-04

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 42.47  E-value: 3.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 226 DLLVIAVGVRAN-IKLAKEAGLQTNR--GILIDEG-GRTSEPDMYAAGDCTEGTEM----IG-GQKAVLALlpNAYLQGE 296
Cdd:PRK11749 377 DLVIKAIGQTPNpLILSTTPGLELNRwgTIIADDEtGRTSLPGVFAGGDIVTGAATvvwaVGdGKDAAEAI--HEYLEGA 454


                 ..
gi 324025196 297 TA 298
Cdd:PRK11749 455 AS 456
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
87-152 6.47e-04

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 41.86  E-value: 6.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 324025196  87 TVALESGMSIAYDKLLLATGSSPFIPPiKGLGEVKNWF-----TFLTLDEakrlqshLRPDSRVLILGAGL 152
Cdd:COG4529  140 RVTLADGETLRADAVVLATGHPPPAPP-PGLAAGSPRYiadpwPPGALAR-------IPPDARVLIIGTGL 202
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 226-274 1.24e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 40.89  E-value: 1.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 324025196 226 DLLVIAVGVRANIK-LAKEAGLQTNRG--ILIDEG-GRTSEPDMYAAGDCTEG 274
Cdd:COG0493  361 DLVILAIGQTPDPSgLEEELGLELDKRgtIVVDEEtYQTSLPGVFAGGDAVRG 413
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
 248-272 2.30e-03

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 40.14  E-value: 2.30e-03
                         10        20
                 ....*....|....*....|....*.
gi 324025196 248 TNRG-ILIDEGGRTSEPDMYAAGDCT 272
Cdd:PRK15317 461 NRRGeIIVDARGATSVPGVFAAGDCT 486
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 219-309 3.65e-03

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 39.71  E-value: 3.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324025196 219 SGHAIGFDLLVIAVGVRANIKLAKEAGLQTNRGILI---DEGGRTSEPDMYAAGDCTEGTEMI-----GGQKAVLALlpN 290
Cdd:PRK12814 420 SEFTLQADTVISAIGQQVDPPIAEAAGIGTSRNGTVkvdPETLQTSVAGVFAGGDCVTGADIAinaveQGKRAAHAI--D 497

                         90
                 ....*....|....*....
gi 324025196 291 AYLQGETAGTNMAGGEASF 309
Cdd:PRK12814 498 LFLNGKPVTAPVQPFNSSY 516
PRK13984 PRK13984
putative oxidoreductase; Provisional
 226-280 5.57e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 38.98  E-value: 5.57e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 324025196 226 DLLVIAVGVRANIKLAKE---AGLQTNRG-ILIDEGGRTSEPDMYAAGDCTEGTEMIGG 280
Cdd:PRK13984 528 DMVVEAIGQAPDYSYLPEelkSKLEFVRGrILTNEYGQTSIPWLFAGGDIVHGPDIIHG 586
Rubredoxin_C pfam18267
Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin ...
 341-362 6.14e-03

Rubredoxin NAD+ reductase C-terminal domain; This is the C-terminal domain of NADH rubredoxin oxidoreductase present in Clostridium acetobutylicum. The majority of obligatory anaerobes detoxify micro-aerobic environments by consuming O2 via H2O-forming NADH oxidase. This enzyme offers an alternate reaction pathway for scavenging of O2 and reactive oxygen species, wherein the reducing equivalent is obtained from NADH.


Pssm-ID: 408082 [Multi-domain]  Cd Length: 70  Bit Score: 35.23  E-value: 6.14e-03
                          10        20
                  ....*....|....*....|..
gi 324025196  341 KNGYKRLFVKDNHLVGCILSGD 362
Cdd:pfam18267  34 NGIYKKLFIRDGKLVGAILIGD 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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