NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|320542841|ref|NP_732017|]
View 

uncharacterized protein Dmel_CG42726 [Drosophila melanogaster]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
112-288 2.12e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.61  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 112 TSSHLKYHLMSHEKQ--SKHSCSVCHKSFKQPIVLQRHMLT-----HNQEKHLCPI--CQKVFRRKSSLASHLAIHSDLg 182
Cdd:COG5048  271 QSSSPNESDSSSEKGfsLPIKSKQCNISFSRSSPLTRHLRSvnhsgESLKPFSCPYslCGKLFSRNDALKRHILLHTSI- 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 183 LQFKCEL--CSKHFQNKAN----LNQHLRKHDKNNIRHMCKV--CQKSFLRQTTLRLHMKRH--SNRERQSCSLCGKSYN 252
Cdd:COG5048  350 SPAKEKLlnSSSKFSPLLNneppQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHlsFRPYNCKNPPCSKSFN 429
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 320542841 253 DPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRH 288
Cdd:COG5048  430 RHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHG 465
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
112-288 2.12e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.61  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 112 TSSHLKYHLMSHEKQ--SKHSCSVCHKSFKQPIVLQRHMLT-----HNQEKHLCPI--CQKVFRRKSSLASHLAIHSDLg 182
Cdd:COG5048  271 QSSSPNESDSSSEKGfsLPIKSKQCNISFSRSSPLTRHLRSvnhsgESLKPFSCPYslCGKLFSRNDALKRHILLHTSI- 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 183 LQFKCEL--CSKHFQNKAN----LNQHLRKHDKNNIRHMCKV--CQKSFLRQTTLRLHMKRH--SNRERQSCSLCGKSYN 252
Cdd:COG5048  350 SPAKEKLlnSSSKFSPLLNneppQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHlsFRPYNCKNPPCSKSFN 429
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 320542841 253 DPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRH 288
Cdd:COG5048  430 RHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHG 465
Chordopox_A33R pfam05966
Chordopoxvirus A33R protein; This family consists of several Chordopoxvirus A33R proteins. ...
151-254 7.13e-03

Chordopoxvirus A33R protein; This family consists of several Chordopoxvirus A33R proteins. A33R plays a role in promoting Ab-resistant cell-to-cell spread of virus and interacts with A36R to incorporate the protein into the outer membrane of intracellular enveloped virions (IEV).


Pssm-ID: 283591  Cd Length: 184  Bit Score: 37.69  E-value: 7.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841  151 HNQEKHLC-PICQKVFRrKSSLASHLAIHSDLGLQF-KCELCSKHFQNKANLNQH-LRKHDKNNIRHMCKVCQKSFLRQT 227
Cdd:pfam05966  32 TNKKKSKClSIGLRVAI-ITSILSLMAIATTLALQYsKCKSVIESAHNEQSYNNYdNITPDANYNIVKLTECQGIVFDYY 110
                          90       100
                  ....*....|....*....|....*..
gi 320542841  228 TLRLHmKRHSNRERQSCSLCGKSYNDP 254
Cdd:pfam05966 111 CYRLV-YEPKTFDEASKDCAKNKGNLP 136
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
112-288 2.12e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.61  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 112 TSSHLKYHLMSHEKQ--SKHSCSVCHKSFKQPIVLQRHMLT-----HNQEKHLCPI--CQKVFRRKSSLASHLAIHSDLg 182
Cdd:COG5048  271 QSSSPNESDSSSEKGfsLPIKSKQCNISFSRSSPLTRHLRSvnhsgESLKPFSCPYslCGKLFSRNDALKRHILLHTSI- 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 183 LQFKCEL--CSKHFQNKAN----LNQHLRKHDKNNIRHMCKV--CQKSFLRQTTLRLHMKRH--SNRERQSCSLCGKSYN 252
Cdd:COG5048  350 SPAKEKLlnSSSKFSPLLNneppQSLQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHlsFRPYNCKNPPCSKSFN 429
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 320542841 253 DPDALGRHLRQHKTAERYRCIQCDITINRKDNMLRH 288
Cdd:COG5048  430 RHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHG 465
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
83-250 3.78e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.76  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841  83 SRTQQYYHLTCGNDLLKKFNCKECGRRFATSSHLKYHL--MSH--EKQSKHSC--SVCHKSFKQPIVLQRHMLTH-NQEK 155
Cdd:COG5048  272 SSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLrsVNHsgESLKPFSCpySLCGKLFSRNDALKRHILLHtSISP 351
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841 156 HLCPI--CQKVFRRKSSLASHLAIH----SDLGLQFKCEL--CSKHFQNKANLNQHLRKHDKNNIRHM-CKVCQKSFLRQ 226
Cdd:COG5048  352 AKEKLlnSSSKFSPLLNNEPPQSLQqykdLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCkNPPCSKSFNRH 431
                        170       180
                 ....*....|....*....|....
gi 320542841 227 TTLRLHMKRHSNRERQSCSLCGKS 250
Cdd:COG5048  432 YNLIPHKKIHTNHAPLLCSILKSF 455
Chordopox_A33R pfam05966
Chordopoxvirus A33R protein; This family consists of several Chordopoxvirus A33R proteins. ...
151-254 7.13e-03

Chordopoxvirus A33R protein; This family consists of several Chordopoxvirus A33R proteins. A33R plays a role in promoting Ab-resistant cell-to-cell spread of virus and interacts with A36R to incorporate the protein into the outer membrane of intracellular enveloped virions (IEV).


Pssm-ID: 283591  Cd Length: 184  Bit Score: 37.69  E-value: 7.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320542841  151 HNQEKHLC-PICQKVFRrKSSLASHLAIHSDLGLQF-KCELCSKHFQNKANLNQH-LRKHDKNNIRHMCKVCQKSFLRQT 227
Cdd:pfam05966  32 TNKKKSKClSIGLRVAI-ITSILSLMAIATTLALQYsKCKSVIESAHNEQSYNNYdNITPDANYNIVKLTECQGIVFDYY 110
                          90       100
                  ....*....|....*....|....*..
gi 320542841  228 TLRLHmKRHSNRERQSCSLCGKSYNDP 254
Cdd:pfam05966 111 CYRLV-YEPKTFDEASKDCAKNKGNLP 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH