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Conserved domains on  [gi|319443730]
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Chain D, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 158-698 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


:

Pssm-ID: 404688  Cd Length: 543  Bit Score: 1169.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  158 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 237
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  238 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 317
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  318 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 397
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  398 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 474
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  475 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 554
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  555 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 634
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730  635 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 698
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-156 1.34e-46

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 165.95  E-value: 1.34e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 156
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 158-698 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1169.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  158 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 237
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  238 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 317
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  318 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 397
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  398 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 474
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  475 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 554
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  555 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 634
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730  635 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 698
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 15-709 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 594.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQ 94
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  95 GALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLvsi 174
Cdd:COG3914  164 EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELL--- 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 175 vaDQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSH 254
Cdd:COG3914  241 --AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPELPPPPNPRDPDRKLRIGYVSADFRRHAVGY 314

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 255 LMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNGKAADRIHQDGIHILVNMNGYTKGARNELFA 334
Cdd:COG3914  315 LLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DEEAAELIRADGIDILVDLSGHTAGNRLGVFA 392

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 335 LRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFigdhanmfphlkkkavidfksnghiydn 414
Cdd:COG3914  393 LRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGSYL---------------------------- 444

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 415 rivlngidlkafldslpdvkivkmkCPDGGDNAdssntalnmPVIPmntiaeavieminrgqiqitingfsisnglattq 494
Cdd:COG3914  445 -------------------------CYQPNDRA---------PEVA---------------------------------- 456

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 495 innkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFP-AVGEPNIQQYAQ 573
Cdd:COG3914  457 ---------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWARILKAVPNSVLLLKGGGlPEARERLRAAAA 521

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 574 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAK 653
Cdd:COG3914  522 ARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGVPVVTLAGETFASRVGASLLTALGLPELIAT 601

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 319443730 654 NRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHY 709
Cdd:COG3914  602 SEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYRQMWQRW 657
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-156 1.34e-46

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 165.95  E-value: 1.34e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 156
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 21-153 5.03e-16

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 78.15  E-value: 5.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   21 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 100
Cdd:TIGR02521  43 EQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQF 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 319443730  101 TRAIQIN--PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 153
Cdd:TIGR02521 123 EQAIEDPlyPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAE 177
TPR_12 pfam13424
Tetratricopeptide repeat;
9-72 1.86e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 65.87  E-value: 1.86e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 72
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 10-202 9.23e-12

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 66.50  E-value: 9.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  10 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT-FADAYSNMGntlk 88
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLG---- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  89 emQDVQG--ALQCYTRAIQI--------NPAFADAHSNLASIHKDsgnIPEAIAS----YRT------------------ 136
Cdd:cd24142   77 --QLSGGeeALQYYEKGIEIleeelqalQAASAEAEEEAEELKRK---LSSALCAlaeiYMTdlcdepdaeqrceelitk 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730 137 ALKLKPDFPDAYCNLAHcLQIV-CDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFR 202
Cdd:cd24142  152 ALELDPTNPEALQTLAS-LRISqQRPDEAKEALRRSLELWKDLKEEDEEEAEEDEAEEEDVPSYEFR 217
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 15-74 1.18e-08

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 56.40  E-value: 1.18e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:NF033920 196 LGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 9-42 4.51e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.59  E-value: 4.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 319443730     9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 42
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 91-184 1.25e-05

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 48.76  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  91 QDVQGALQCYTRAIQINPAfADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLqivCDWTDYDERMKK 170
Cdd:PRK09782 590 GQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLRAALELEPNNSNYQAALGYAL---WDSGDIAQSREM 665

                         90
                 ....*....|....
gi 319443730 171 LVSIVADQLEKNRL 184
Cdd:PRK09782 666 LERAHKGLPDDPAL 679
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 6-190 8.06e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 42.98  E-value: 8.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSL---NNLANIKREQGNIEEAVRLYRKALEVFPE-FAAAH-------SNLASVLQQQGKLQEALmhykeaiRISp 74
Cdd:NF040586 641 PDHPDTLaaaLSLANDLRALGDADEARELAREVLDRYRRvLGEDHpftlacrNNLAVLLRALGDPEEAR-------ELA- 712

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  75 tfadaysnmGNTLKEMQDVQGALQCYTRAIQInpafadahsNLASIHKDSGNIPEAIAS---------YRTALKLKPDFP 145
Cdd:NF040586 713 ---------EAALEGLRERLGPDHPYTLAAAV---------NLANDLAALGDLDAALGEealerlrrlLGEDLRAGPDHP 774

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 319443730 146 D---AYCNLAHCLQIvcdwTDYDERMKKLVSIVADQLEKnRLPSVHPH 190
Cdd:NF040586 775 DtlaCAANLALDLRA----TGRTEEAEELRADTLARLRR-VLGPDHPD 817
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 432-512 3.42e-03

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 37.26  E-value: 3.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 432 DVKIVKMKCPDGGDNADSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 510
Cdd:NF038028   1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                 ..
gi 319443730 511 VT 512
Cdd:NF038028  70 FT 71
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 158-698 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1169.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  158 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 237
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  238 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 317
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  318 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 397
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  398 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 474
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  475 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 554
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  555 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 634
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730  635 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 698
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 15-709 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 594.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQ 94
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  95 GALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLvsi 174
Cdd:COG3914  164 EAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELL--- 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 175 vaDQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSH 254
Cdd:COG3914  241 --AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPELPPPPNPRDPDRKLRIGYVSADFRRHAVGY 314

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 255 LMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNGKAADRIHQDGIHILVNMNGYTKGARNELFA 334
Cdd:COG3914  315 LLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DEEAAELIRADGIDILVDLSGHTAGNRLGVFA 392

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 335 LRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFigdhanmfphlkkkavidfksnghiydn 414
Cdd:COG3914  393 LRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGSYL---------------------------- 444

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 415 rivlngidlkafldslpdvkivkmkCPDGGDNAdssntalnmPVIPmntiaeavieminrgqiqitingfsisnglattq 494
Cdd:COG3914  445 -------------------------CYQPNDRA---------PEVA---------------------------------- 456

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 495 innkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFP-AVGEPNIQQYAQ 573
Cdd:COG3914  457 ---------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWARILKAVPNSVLLLKGGGlPEARERLRAAAA 521

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 574 NMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAK 653
Cdd:COG3914  522 ARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGVPVVTLAGETFASRVGASLLTALGLPELIAT 601

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 319443730 654 NRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHY 709
Cdd:COG3914  602 SEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYRQMWQRW 657
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-156 1.34e-46

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 165.95  E-value: 1.34e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 156
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-148 4.81e-37

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 138.99  E-value: 4.81e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG0457   39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGL 118

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 148
Cdd:COG0457  119 ALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAA 181
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
36-156 1.37e-35

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 135.13  E-value: 1.37e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  36 LEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 115
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 319443730 116 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 156
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 9-144 4.51e-31

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 118.37  E-value: 4.51e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 88
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 319443730  89 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 144
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 6-206 1.96e-30

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 120.99  E-value: 1.96e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG2956   73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYD 165
Cdd:COG2956  153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEAL 232

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 319443730 166 ERMKKLVSIVADQLEKNRLpsvhphhSMLYPLSHGFRKAIA 206
Cdd:COG2956  233 ELLRKALELDPSDDLLLAL-------ADLLERKEGLEAALA 266
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 6-152 5.32e-30

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 119.83  E-value: 5.32e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG2956   39 PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAE 118

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:COG2956  119 IYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA 185
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
6-140 9.15e-25

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.93  E-value: 9.15e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG0457   73 PDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI 152

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 140
Cdd:COG0457  153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 21-152 6.61e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 102.11  E-value: 6.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  21 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 100
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 319443730 101 TRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
40-180 8.23e-24

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 100.37  E-value: 8.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  40 PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLAS 119
Cdd:COG4785   70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGI 149

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 319443730 120 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVcdwtDYDERMKKLVSIVADQLE 180
Cdd:COG4785  150 ALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKL----DPEKALALLLEDWATAYL 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 27-148 9.54e-24

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 97.00  E-value: 9.54e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  27 EAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 106
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 319443730 107 NPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 148
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 43-178 4.54e-23

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 95.64  E-value: 4.54e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  43 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 122
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 319443730 123 DSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQ 178
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 6-120 2.43e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 93.15  E-value: 2.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 120
Cdd:COG4235   94 AAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 6-110 3.58e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 92.95  E-value: 3.58e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:COG4783   35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                         90       100
                 ....*....|....*....|....*
gi 319443730  86 TLKEMQDVQGALQCYTRAIQINPAF 110
Cdd:COG4783  115 AYRALGRPDEAIAALEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
5-137 2.74e-21

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 93.06  E-value: 2.74e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   5 CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG 84
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 319443730  85 NTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNiPEAIASYRTA 137
Cdd:COG4785  149 IALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDP-EKALALLLED 200
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
18-109 5.07e-21

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 87.92  E-value: 5.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  18 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMhYKEAIRISPTFADAYSNMGNTLKEMQDVQGAL 97
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 319443730  98 QCYTRAIQINPA 109
Cdd:COG3063   80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 9-108 1.03e-20

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 89.25  E-value: 1.03e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 88
Cdd:COG5010   54 FAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLL 133

                         90       100
                 ....*....|....*....|
gi 319443730  89 EMQDVQGALQCYTRAIQINP 108
Cdd:COG5010  134 SLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 26-142 1.23e-20

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 89.25  E-value: 1.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  26 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 105
Cdd:COG5010   37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 319443730 106 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 142
Cdd:COG5010  117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
52-143 3.51e-20

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 85.61  E-value: 3.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  52 VLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQcYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 131
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 319443730 132 ASYRTALKLKPD 143
Cdd:COG3063   80 AYLERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 61-152 1.59e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 79.28  E-value: 1.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  61 EALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 140
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|..
gi 319443730 141 KPDFPDAYCNLA 152
Cdd:COG4235   81 DPDNPEALYLLG 92
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 21-153 5.03e-16

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 78.15  E-value: 5.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   21 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 100
Cdd:TIGR02521  43 EQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQF 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 319443730  101 TRAIQIN--PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 153
Cdd:TIGR02521 123 EQAIEDPlyPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAE 177
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 30-155 1.14e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 75.00  E-value: 1.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  30 RLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 109
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 319443730 110 FADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 155
Cdd:COG5010   87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 55-161 1.90e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.08  E-value: 1.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  55 QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASY 134
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELL 99

                         90       100
                 ....*....|....*....|....*..
gi 319443730 135 RTALKLKPDFPDAYCNLAHCLQIVCDW 161
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDW 126
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-147 3.39e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 79.74  E-value: 3.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 530 PKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGR 609

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:TIGR02917 610 AQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 6-74 6.31e-15

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 72.69  E-value: 6.31e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
6-74 1.17e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 69.81  E-value: 1.17e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRlYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:COG3063   23 PDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-147 1.37e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.82  E-value: 1.37e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 156 PRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALAT 235

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:TIGR02917 236 ILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 6-147 5.52e-14

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 71.98  E-value: 5.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRiSPTF---ADAYSN 82
Cdd:TIGR02521  62 PDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE-DPLYpqpARSLEN 140

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 319443730   83 MGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:TIGR02521 141 AGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAYLERYQQTYNQTAES 205
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
89-180 7.12e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 67.89  E-value: 7.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  89 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAsYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERM 168
Cdd:COG3063    4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82

                         90
                 ....*....|..
gi 319443730 169 KKLVSIVADQLE 180
Cdd:COG3063   83 ERALELDPSALR 94
TPR_12 pfam13424
Tetratricopeptide repeat;
9-72 1.86e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 65.87  E-value: 1.86e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 72
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-176 4.80e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 4.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALE-------VFPEFAAAHS---------------------NLASVLQQQG 57
Cdd:TIGR02917  53 PNDAEARFLLGKIYLALGDYAAAEKELRKALSlgypknqVLPLLARAYLlqgkfqqvldelpgktllddeGAAELLALRG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   58 -------KLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEA 130
Cdd:TIGR02917 133 laylglgQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELA 212

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 319443730  131 IASYRTALKLKPDFPDAYCNLAhclQIVCDWTDYDERMKKLVSIVA 176
Cdd:TIGR02917 213 LAAYRKAIALRPNNIAVLLALA---TILIEAGEFEEAEKHADALLK 255
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 10-202 9.23e-12

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 66.50  E-value: 9.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  10 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT-FADAYSNMGntlk 88
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLG---- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  89 emQDVQG--ALQCYTRAIQI--------NPAFADAHSNLASIHKDsgnIPEAIAS----YRT------------------ 136
Cdd:cd24142   77 --QLSGGeeALQYYEKGIEIleeelqalQAASAEAEEEAEELKRK---LSSALCAlaeiYMTdlcdepdaeqrceelitk 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730 137 ALKLKPDFPDAYCNLAHcLQIV-CDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFR 202
Cdd:cd24142  152 ALELDPTNPEALQTLAS-LRISqQRPDEAKEALRRSLELWKDLKEEDEEEAEEDEAEEEDVPSYEFR 217
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-152 1.32e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.19  E-value: 1.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTfADAYSNMGN 85
Cdd:TIGR02917 666 PDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPS-SQNAIKLHR 744

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:TIGR02917 745 ALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLA 811
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-178 4.75e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 66.26  E-value: 4.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYsnmgN 85
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAI----L 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   86 TLKEMQDVQG----ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDW 161
Cdd:TIGR02917 538 ALAGLYLRTGneeeAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDL 617

                         170
                  ....*....|....*..
gi 319443730  162 TDYDERMKKLVSIVADQ 178
Cdd:TIGR02917 618 NKAVSSFKKLLALQPDS 634
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-142 1.43e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 64.72  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQ 677

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 142
Cdd:TIGR02917 678 LLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP 734
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-153 1.52e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 64.72  E-value: 1.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 496 PDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQ 575

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 153
Cdd:TIGR02917 576 YYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLAD 643
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-147 4.63e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.18  E-value: 4.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   22 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 101
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYR 217

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 319443730  102 RAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLA 263
TPR_12 pfam13424
Tetratricopeptide repeat;
41-109 8.84e-10

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 55.47  E-value: 8.84e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   41 EFAAAHSNLASVLQQQGKLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 109
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 96-155 1.23e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 1.23e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  96 ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 155
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL 61
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 21-105 1.37e-09

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 56.15  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  21 EQGNIEEAVRLYRKALEVFP--EFAA-AHSNLASVLQQQGKLQEALMHYKEAIRI---SPTFADAYSNMGNTLKEMQDVQ 94
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPnsPLAPdALYWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|.
gi 319443730  95 GALQCYTRAIQ 105
Cdd:COG1729   85 KARATLEELIK 95
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-147 2.14e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.87  E-value: 2.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVL-------------------------------- 53
Cdd:TIGR02917 190 PGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILieagefeeaekhadallkkapnsplahylkal 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   54 --QQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 131
Cdd:TIGR02917 270 vdFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAI 349

                         170
                  ....*....|....*.
gi 319443730  132 ASYRTALKLKPDFPDA 147
Cdd:TIGR02917 350 ATLSPALGLDPDDPAA 365
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 6-185 4.16e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 59.61  E-value: 4.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR00990 328 EKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQ 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAhclQIVCDWTDYD 165
Cdd:TIGR00990 408 LHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYG---ELLLDQNKFD 484

                         170       180
                  ....*....|....*....|
gi 319443730  166 ERMKKLVSIVAdqLEKNRLP 185
Cdd:TIGR00990 485 EAIEKFDTAIE--LEKETKP 502
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-132 6.85e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 59.33  E-value: 6.85e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQgKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 767 PNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLAPNIPAILDTLGW 845

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIA 132
Cdd:TIGR02917 846 LLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 14-74 8.08e-09

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 52.34  E-value: 8.08e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730   14 NLANIKREQGNIEEAVRLYRKALEVF---PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 15-74 1.18e-08

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 56.40  E-value: 1.18e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:NF033920 196 LGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-142 3.72e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 3.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 394 PENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGA 473

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 142
Cdd:TIGR02917 474 IYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDP 530
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 55-147 7.20e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 51.15  E-value: 7.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  55 QQGKLQEALMHYKEAIRI---SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIP 128
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|....*....
gi 319443730 129 EAIASYRTALKLKPDFPDA 147
Cdd:COG1729   85 KARATLEELIKKYPDSEAA 103
TPR_11 pfam13414
TPR repeat;
16-57 8.20e-08

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 49.01  E-value: 8.20e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 319443730   16 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQG 57
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 9-152 9.69e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 9.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 88
Cdd:TIGR02917 736 SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL 815

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730   89 EMQDVQgALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:TIGR02917 816 ELKDPR-ALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLA 878
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-152 1.18e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    3 GSCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 82
Cdd:TIGR02917 357 GLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLL 436

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   83 MGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:TIGR02917 437 LILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLA 506
TPR_11 pfam13414
TPR repeat;
55-91 1.43e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 48.24  E-value: 1.43e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 319443730   55 QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQ 91
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_11 pfam13414
TPR repeat;
120-153 1.52e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 48.24  E-value: 1.52e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730  120 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 153
Cdd:pfam13414   3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGL 36
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-147 3.21e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 3.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   22 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 101
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLA 387

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 319443730  102 RAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:TIGR02917 388 KATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRA 433
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
65-155 3.52e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 3.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  65 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAiQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 144
Cdd:COG4785   28 ALLFAAVLALAIALADLALALAAAALAAAALAAERIDRA-LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDL 106

                         90
                 ....*....|.
gi 319443730 145 PDAYCNLAHCL 155
Cdd:COG4785  107 AEAYNNRGLAY 117
COG3899 COG3899
Predicted ATPase [General function prediction only];
20-147 9.15e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 52.55  E-value: 9.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   20 REQGNIEEAVRLYRKALEVFPEF------AAAHSNLASVLQQQGKLQEALMHYKEAIRI-------------SPTFADAY 80
Cdd:COG3899   716 LARGAYAEALRYLERALELLPPDpeeeyrLALLLELAEALYLAGRFEEAEALLERALAAralaalaalrhgnPPASARAY 795

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 319443730   81 SNMGNTLkeMQDVQGALQCYTRAIQINPAF------ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 147
Cdd:COG3899   796 ANLGLLL--LGDYEEAYEFGELALALAERLgdrrleARALFNLGFILHWLGPLREALELLREALEAGLETGDA 866
TPR_1 pfam00515
Tetratricopeptide repeat;
77-108 2.02e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 44.72  E-value: 2.02e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 319443730   77 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 108
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 6-143 2.81e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 2.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKReqGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR02917 430 LGRADLLLILSYLRS--GQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLAR 507

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 143
Cdd:TIGR02917 508 IDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQ 565
TPR_11 pfam13414
TPR repeat;
84-125 2.85e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 44.38  E-value: 2.85e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 319443730   84 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSG 125
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 9-74 3.20e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.52  E-value: 3.20e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 319443730   9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE---FAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 74
Cdd:COG1729   30 PDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKARATLEELIKKYP 98
TPR_1 pfam00515
Tetratricopeptide repeat;
9-42 3.70e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.95  E-value: 3.70e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 42
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
9-38 3.98e-06

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 44.03  E-value: 3.98e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEV 38
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAI 31
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 9-42 4.51e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 43.59  E-value: 4.51e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 319443730     9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 42
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
43-76 6.29e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.18  E-value: 6.29e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730   43 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 76
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 91-184 1.25e-05

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 48.76  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  91 QDVQGALQCYTRAIQINPAfADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLqivCDWTDYDERMKK 170
Cdd:PRK09782 590 GQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLRAALELEPNNSNYQAALGYAL---WDSGDIAQSREM 665

                         90
                 ....*....|....
gi 319443730 171 LVSIVADQLEKNRL 184
Cdd:PRK09782 666 LERAHKGLPDDPAL 679
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 43-76 1.31e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 1.31e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 319443730    43 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 76
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 77-110 1.38e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 1.38e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 319443730    77 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 110
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
111-144 2.14e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 2.14e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730  111 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 144
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 111-144 3.99e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 3.99e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 319443730   111 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 144
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 9-41 4.30e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 40.97  E-value: 4.30e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 41
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 22-130 4.63e-05

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 46.15  E-value: 4.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   22 QGNIEEAVRLYRKALEvfpeFAAAHSN----------LASVLQQQGKLQEALMHYKEAIR--------ISPTFADAYSNM 83
Cdd:pfam17874  53 LGDLDAALQAMREAEA----LARRADSphvtlwallqQGEILRAQGRLHQALETYQQALQlardhglqHLPLHGFLLVGL 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 319443730   84 GNTLKEMQDVQGALQCYTRAIQI-----NPAFADAHSNLASIHKDSGNIPEA 130
Cdd:pfam17874 129 ADLLYEWNDLEEAEQHAQQGIQLgrqwePDAAVDAYVLLARIALAQGELEEA 180
TPR_19 pfam14559
Tetratricopeptide repeat;
56-120 5.10e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.80  E-value: 5.10e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 319443730   56 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 120
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_19 pfam14559
Tetratricopeptide repeat;
22-62 5.26e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.42  E-value: 5.26e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 319443730   22 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 62
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEA 41
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-211 7.63e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 7.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   50 ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI--------- 120
Cdd:TIGR02917  29 AKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAyllqgkfqq 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  121 --------------------------HKDSGNIPEAIASYRTALKLKPDFPDAYCNLAhclQIVCDWTDYDERMKklvsI 174
Cdd:TIGR02917 109 vldelpgktllddegaaellalrglaYLGLGQLELAQKSYEQALAIDPRSLYAKLGLA---QLALAENRFDEARA----L 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 319443730  175 VADQLEKNrlPSVHPHHSML--YPLSHG--------FRKAIAERHGN 211
Cdd:TIGR02917 182 IDEVLTAD--PGNVDALLLKgdLLLSLGnielalaaYRKAIALRPNN 226
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
120-155 8.36e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 8.36e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 319443730 120 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 155
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLL 36
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 23-140 1.04e-04

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 43.06  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    23 GNIEEAVRLYRKAL-----EVFPEFAAAhsnlASVLQQQGKLQEALMHYKEAIrisptfADAYSNMGntlkemqDVQGAL 97
Cdd:smart01043  19 ADPEAALALLEAALalyrgPLLADVPDE----DWAEAERERLRELRLEALEAL------AEALLALG-------RHEEAL 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 319443730    98 QCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 140
Cdd:smart01043  82 ALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLRRL 124
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 111-143 1.38e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.43  E-value: 1.38e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730  111 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 143
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 82-143 1.43e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.40  E-value: 1.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 319443730   82 NMGNTLKEMQDVQGALQCYTRAIQIN---PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 143
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TPR_12 pfam13424
Tetratricopeptide repeat;
9-41 1.63e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.45  E-value: 1.63e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 41
Cdd:pfam13424  45 ATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 77-108 1.77e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.04  E-value: 1.77e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 319443730   77 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 108
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_14 pfam13428
Tetratricopeptide repeat;
15-52 1.82e-04

Tetratricopeptide repeat;


Pssm-ID: 463874 [Multi-domain]  Cd Length: 44  Bit Score: 39.33  E-value: 1.82e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 319443730   15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASV 52
Cdd:pfam13428   7 LARALLALGDPDEALALLERALALDPDDPEAWLALAQL 44
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 21-143 2.54e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 44.69  E-value: 2.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   21 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPtfaDAYSN-----------------M 83
Cdd:PRK11447  281 DSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDP---HSSNRdkwesllkvnrywlliqQ 357

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   84 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 143
Cdd:PRK11447  358 GDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPG 417
TPR_17 pfam13431
Tetratricopeptide repeat;
31-63 2.71e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 38.68  E-value: 2.71e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730   31 LYRKALEVFPEFAAAHSNLASVLQQQGKLQEAL 63
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETAL 33
TPR_19 pfam14559
Tetratricopeptide repeat;
92-148 2.96e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.49  E-value: 2.96e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   92 DVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 148
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYA 59
TPR COG0790
TPR repeat [General function prediction only];
8-156 3.02e-04

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 42.99  E-value: 3.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   8 HADSLNNLANIKRE----QGNIEEAVRLYRKALEVfpEFAAAHSNLAsVLQQQGK-----LQEALMHYKEAIRIspTFAD 78
Cdd:COG0790   62 GAEAQYNLGLMYAEgrgvPKDYEKALEWFEKAAEQ--GDAEAQYNLG-LMYEEGLgvpqdYAKALEWYEKAAEQ--GDAD 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  79 AYSNMGNTLKE----MQDVQGALQCYTRAIQINpaFADAHSNLASIHKD----SGNIPEAIASYRTALKLKpdFPDAYCN 150
Cdd:COG0790  137 AQYNLGLLYLNgegvPKDPAKAAEWYRKAAEQG--DADAQYNLGVLYENgrgvPKDPAKALEWYRKAAEQG--DADAQYN 212


                 ....*.
gi 319443730 151 LAHCLQ 156
Cdd:COG0790  213 LGRLYL 218
TPR_7 pfam13176
Tetratricopeptide repeat;
11-38 4.31e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.29  E-value: 4.31e-04
                          10        20
                  ....*....|....*....|....*...
gi 319443730   11 SLNNLANIKREQGNIEEAVRLYRKALEV 38
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALAL 28
TPR_17 pfam13431
Tetratricopeptide repeat;
65-98 4.74e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 37.91  E-value: 4.74e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730   65 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQ 98
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 6-152 5.54e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.43  E-value: 5.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730    6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 85
Cdd:TIGR00990 362 PRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGV 441

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730   86 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 152
Cdd:TIGR00990 442 TQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVL 508
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 22-105 6.52e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 42.68  E-value: 6.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   22 QGNIEEAVRLYRKAL-----EVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRisptFADAYSNMGNT------LKEM 90
Cdd:pfam17874  14 KGDAERALELAEQALallpeDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEA----LARRADSPHVTlwallqQGEI 89

                          90
                  ....*....|....*....
gi 319443730   91 QDVQG----ALQCYTRAIQ 105
Cdd:pfam17874  90 LRAQGrlhqALETYQQALQ 108
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
6-41 7.23e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 7.23e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 41
Cdd:COG3063   56 PNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 24-137 7.81e-04

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 42.18  E-value: 7.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  24 NIEEAVRLYRKAlevfpefaAAHSNLASVLQQQGK--LQEALMHYK-----EAirisptfADAYSNMGNTLKEMqDVQGA 96
Cdd:cd15832   27 KYEEAAELYEKA--------ANAFKLAKNWEEAGDafLKAAECQLKldskhDA-------ANAYVEAAKCYKKV-DPQEA 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 319443730  97 LQCYTRAIQI-------NPAfADAHSNLASIH-KDSGNIPEAIASYRTA 137
Cdd:cd15832   91 VNCLEKAIEIytemgrfRQA-AKHLKEIAELYeNELGDLDKAIEAYEQA 138
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 6-190 8.06e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 42.98  E-value: 8.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSL---NNLANIKREQGNIEEAVRLYRKALEVFPE-FAAAH-------SNLASVLQQQGKLQEALmhykeaiRISp 74
Cdd:NF040586 641 PDHPDTLaaaLSLANDLRALGDADEARELAREVLDRYRRvLGEDHpftlacrNNLAVLLRALGDPEEAR-------ELA- 712

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  75 tfadaysnmGNTLKEMQDVQGALQCYTRAIQInpafadahsNLASIHKDSGNIPEAIAS---------YRTALKLKPDFP 145
Cdd:NF040586 713 ---------EAALEGLRERLGPDHPYTLAAAV---------NLANDLAALGDLDAALGEealerlrrlLGEDLRAGPDHP 774

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 319443730 146 D---AYCNLAHCLQIvcdwTDYDERMKKLVSIVADQLEKnRLPSVHPH 190
Cdd:NF040586 775 DtlaCAANLALDLRA----TGRTEEAEELRADTLARLRR-VLGPDHPD 817
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 43-75 8.77e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 8.77e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730   43 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 75
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
9-139 1.00e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 41.41  E-value: 1.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   9 ADSLNN---LANIKREQGNIEEAVRLYRKALE-VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF--ADAYSN 82
Cdd:COG4700   86 ADTVQNrvrLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLL 165

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 319443730  83 MGNTLKEMQDVQGALQCYTRAIQINPaFADAHSNLASIHKDSGNIPEAIASYRTALK 139
Cdd:COG4700  166 YARALEALGDLEAAEAELEALARRYS-GPEARYRYAKFLARQGRTAEAKELLEEILD 221
TPR_8 pfam13181
Tetratricopeptide repeat;
9-41 1.08e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.99  E-value: 1.08e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730    9 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 41
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 89-156 1.10e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 1.10e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 319443730  89 EMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIPEAIASYRTALKLKPD---FPDAYCNLAHCLQ 156
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYL 78
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 15-140 1.37e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.89  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN----MGNTL--- 87
Cdd:TIGR00990 439 LGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNvlplINKALalf 518

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 319443730   88 KEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 140
Cdd:TIGR00990 519 QWKQDFIEAENLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAEL 571
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 15-109 1.46e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 40.61  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALE--VFPEFAA-AHSNLASVLQQQGKLQEALMHYKEAirISPTFADAYSN-MGNTLKEM 90
Cdd:COG2976   96 LAKAAVDAGDLDKAAAQLQWVLDnaKDPALKAlARLRLARVLLAQKKYDEALATLDAV--KPEAFAALYAElRGDILLAQ 173

                         90
                 ....*....|....*....
gi 319443730  91 QDVQGALQCYTRAIQINPA 109
Cdd:COG2976  174 GDKAEARAAYQKALAALPE 192
COG3899 COG3899
Predicted ATPase [General function prediction only];
15-118 2.31e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.38  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   15 LANIKREQGNIEEAVRLYRKALEV-------------FPEFAAAHSNLASVLqqQGKLQEALMHYKEAIRISPTF----- 76
Cdd:COG3899   751 LAEALYLAGRFEEAEALLERALAAralaalaalrhgnPPASARAYANLGLLL--LGDYEEAYEFGELALALAERLgdrrl 828

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 319443730   77 -ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLA 118
Cdd:COG3899   829 eARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALL 871
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 12-88 2.75e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 39.27  E-value: 2.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  12 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVL-------QQQGKLQEALMHY-------KEAIRISPtfa 77
Cdd:PRK02603  75 LYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFdkaaeywKQAIRLAP--- 151

                         90
                 ....*....|.
gi 319443730  78 DAYSNMGNTLK 88
Cdd:PRK02603 152 NNYIEAQNWLK 162
TPR_7 pfam13176
Tetratricopeptide repeat;
113-148 2.83e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.83e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 319443730  113 AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 148
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_10 pfam13374
Tetratricopeptide repeat;
43-72 2.89e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.94  E-value: 2.89e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 319443730   43 AAAHSNLASVLQQQGKLQEALMHYKEAIRI 72
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAI 31
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 21-105 3.06e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 40.28  E-value: 3.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  21 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTfADAYSNMGNTLKEMQDVQGALQCY 100
Cdd:COG3071  236 QGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHY 314


                 ....*
gi 319443730 101 TRAIQ 105
Cdd:COG3071  315 RKALA 319
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 19-73 3.24e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 40.41  E-value: 3.24e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 319443730  19 KREQGNIEEAVRLYRKALEVF---------PE----FAAAHSNLASVLQQQGKLQEALMHYKEAIRIS 73
Cdd:cd24145  222 KSRDQLLEAALKWAQKALDVAksikpkdrdPEcdqaCALALYNLGVIAEMLGNLDEARKLYKEAISLA 289
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
6-71 3.25e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.90  E-value: 3.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730   6 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNL--------------------ASVLQQQGKLQEALMH 65
Cdd:COG4785  138 PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLylaerkldpekalallledwATAYLLQGDTEEAREL 217


                 ....*.
gi 319443730  66 YKEAIR 71
Cdd:COG4785  218 FKLALA 223
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 96-148 3.34e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 40.54  E-value: 3.34e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 319443730  96 ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 148
Cdd:PLN03088  21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAY 73
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 432-512 3.42e-03

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 37.26  E-value: 3.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730 432 DVKIVKMKCPDGGDNADSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 510
Cdd:NF038028   1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                 ..
gi 319443730 511 VT 512
Cdd:NF038028  70 FT 71
TPR_8 pfam13181
Tetratricopeptide repeat;
111-143 3.79e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.45  E-value: 3.79e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 319443730  111 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 143
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_17 pfam13431
Tetratricopeptide repeat;
99-132 4.65e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 4.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 319443730   99 CYTRAIQINPAFADAHSNLASIHKDSGNIPEAIA 132
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 15-72 5.22e-03

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 38.05  E-value: 5.22e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 319443730    15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 72
Cdd:smart01043  67 LAEALLALGRHEEALALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLRRL 124
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 15-142 5.80e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 39.79  E-value: 5.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  15 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF--------ADAYsnmgnt 86
Cdd:PRK11788 186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEYlsevlpklMECY------ 259

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 319443730  87 lKEMQDVQGALQCYTRAIQINPaFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 142
Cdd:PRK11788 260 -QALGDEAEGLEFLRRALEEYP-GADLLLALAQLLEEQEGPEAAQALLREQLRRHP 313
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 23-106 6.70e-03

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 39.10  E-value: 6.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 319443730  23 GNIEEAVRLYRKALEVFPE---F---AAAHSNLASVLQQQ-GKLQEALMHYKEAirisptfADAYSNMG-----NTLKE- 89
Cdd:cd15832   85 VDPQEAVNCLEKAIEIYTEmgrFrqaAKHLKEIAELYENElGDLDKAIEAYEQA-------ADYYEGEGanslaNKCYLk 157

                         90
                 ....*....|....*..
gi 319443730  90 MQDVQGALQCYTRAIQI 106
Cdd:cd15832  158 VADLAAQLEDYDKAIEI 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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