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Conserved domains on  [gi|31874454|emb|CAD97796|]
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hypothetical protein, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LapB super family cl34526
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
3-54 1.23e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG2956:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 36.63  E-value: 1.23e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 31874454   3 EQAMEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLpSARALLEI 54
Cdd:COG2956 134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD-CARALLLL 184
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
3-54 1.23e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 36.63  E-value: 1.23e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 31874454   3 EQAMEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLpSARALLEI 54
Cdd:COG2956 134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD-CARALLLL 184
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
13-55 2.15e-03

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 35.61  E-value: 2.15e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 31874454    13 AEKCVEIAREALNAGNREKAQRFLQKAEKLYPLP--SARALLEII 55
Cdd:TIGR03302  33 AEELYEEAKEALDSGDYTEAIKYFEALESRYPFSpyAEQAQLDLA 77
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
3-54 1.23e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 36.63  E-value: 1.23e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 31874454   3 EQAMEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLpSARALLEI 54
Cdd:COG2956 134 ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD-CARALLLL 184
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
13-55 2.15e-03

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 35.61  E-value: 2.15e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 31874454    13 AEKCVEIAREALNAGNREKAQRFLQKAEKLYPLP--SARALLEII 55
Cdd:TIGR03302  33 AEELYEEAKEALDSGDYTEAIKYFEALESRYPFSpyAEQAQLDLA 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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