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Conserved domains on  [gi|317097458|ref|YP_004123677|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Locusta migratoria manilensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.54e-93

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 279.79  E-value: 9.54e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   1 MYNNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  81 KYMMwwdNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKmSSFLFVVIMMGIIV 160
Cdd:MTH00160  81 NLML---FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 161 GAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 241 MTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVMALP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 317097458 321 ILSMISTMGLICTSNFMLF 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.54e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 279.79  E-value: 9.54e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   1 MYNNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  81 KYMMwwdNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKmSSFLFVVIMMGIIV 160
Cdd:MTH00160  81 NLML---FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 161 GAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 241 MTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVMALP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 317097458 321 ILSMISTMGLICTSNFMLF 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 4.69e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 96.34  E-value: 4.69e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSSLmmGTILSISSNSWLGIWMGLEinLLSI-----IPMLTDNKNSmiNEPAIKYFIIQSMASTMLL--ISIL---- 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLE--LLSLslyvlVAFRRDDRRS--SEAALKYFLLGALSSGFLLygISLLygat 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  77 ----IIQMKYMMWWDNKNIPSMMIMSSMMMK-----MGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPM---------M 138
Cdd:COG1007  181 gslnLAGIAAALAAGGANSPLLLLGLVLVLAglafkLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveA 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 139 TMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWM-ISSMTISENTWE---FYFLIYSTLNV----I 210
Cdd:COG1007  261 FPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafaV 340

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 211 IIFM----FKTMNLFFLNQIYSASYFKTeikFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITL 286
Cdd:COG1007  341 ILLLsrkgGEAEEIEDLAGLARRSPLLA---LAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISA 417


                 ....*.
gi 317097458 287 YYYMRI 292
Cdd:COG1007  418 YYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-277 4.67e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.52  E-value: 4.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   24 SNSWLGIWMGLEINLLSIIPMLTDNKNSMI-NEPAIKYFIIQSMASTMLLISILII--------------QMKYMMWWDN 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRsSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   89 KNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSW-INCLMLMTWQKIAPMMTM-------SYCIKMSSFLFVVIMMGIIV 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  161 GAMGGLNQTSLRQILAYSSISHLGWMISSM----TISENTWEFYFLIYSTLNVIIIFMF-----KTMNLFFLNQIYSASY 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 317097458  232 FKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLL 277
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-338 1.51e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.07  E-value: 1.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   17 GTILSISSNSWLGIWMGLEI-NLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLL---------------ISILIIQM 80
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLfgisliygftgslnfEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   81 KYMMWWDNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIA---PMMTMSYCI------KMSSFLF 151
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIlfgfseAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  152 VVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISEntwefYFLIYSTLNVIIIFMFKTMNLF---------- 221
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGT-----LEGIKAVLFYIFIYALMSLGAFgvlsllrsyk 348

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  222 -----FLNQIYSASYFKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRIsfSA 296
Cdd:TIGR01770 349 dewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VK 426

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 317097458  297 IIMLHNENSWLTSIKMNKLVMALPILSMISTMGLICTSNFML 338
Cdd:TIGR01770 427 VMYFDKPERRIPSNPQSKAQSLLLSISALFILFLGLFPSLIL 468
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 9.54e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 279.79  E-value: 9.54e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   1 MYNNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQM 80
Cdd:MTH00160   1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  81 KYMMwwdNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKmSSFLFVVIMMGIIV 160
Cdd:MTH00160  81 NLML---FNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-NNFIIIIIILSAII 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 161 GAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMM 240
Cdd:MTH00160 157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 241 MTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVMALP 320
Cdd:MTH00160 237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*....
gi 317097458 321 ILSMISTMGLICTSNFMLF 339
Cdd:MTH00160 317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-340 1.59e-58

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 192.45  E-value: 1.59e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   3 NNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKY 82
Cdd:MTH00041   2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  83 MMWWDNK---NIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKM--SSFLFVVIMMG 157
Cdd:MTH00041  82 GSWSINGplnTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLlnSNILILCGILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 158 IIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIK 237
Cdd:MTH00041 162 VLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 238 FMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENS-----WLTSIKM 312
Cdd:MTH00041 242 FLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGNI 321

                        330       340
                 ....*....|....*....|....*...
gi 317097458 313 NKLVMALPILSMISTMGLICTSNFMLFY 340
Cdd:MTH00041 322 TVYGVILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 7-337 1.34e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 184.64  E-value: 1.34e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   7 KLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISIlIIQMKYMMWW 86
Cdd:MTH00112   6 KLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSS-TTNAWNTGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  87 D----NKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPM--MTMSYCIKMSSFLFVVIMMGIIV 160
Cdd:MTH00112  85 DitqlTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLtlLLMTSNSLNPTLLLTLAILSTLI 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 161 GAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMM 240
Cdd:MTH00112 165 GGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 241 MTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIML--HNENS---WLTSIKMNKL 315
Cdd:MTH00112 245 MLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLppNTTNMmmkWRTKPKKNTL 324

                        330       340
                 ....*....|....*....|..
gi 317097458 316 vmaLPILSMISTMGLICTSNFM 337
Cdd:MTH00112 325 ---TATLTTLSTLLLPLSPMIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 1.76e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 184.35  E-value: 1.76e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  10 FLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIiQMKYMMWWDNK 89
Cdd:MTH00070   9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTI-NAWFTGEWTIM 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  90 N----IPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPM--MTMSYCIKMSSFLFVVIMMGIIVGAM 163
Cdd:MTH00070  88 NmqtpLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMalLIQISHLLNSNLLIIMGLLSTLIGGW 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 164 GGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIySASYFKTEIKF-MMMT 242
Cdd:MTH00070 168 GGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKL-SSSWSKNPTLTsMMML 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 243 SLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLH--NENSWLTSIKMNKLVMALP 320
Cdd:MTH00070 247 TLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSpnTSNSKLYWRFKNKTNNLLS 326

                        330       340
                 ....*....|....*....|
gi 317097458 321 ILSMISTMGLICTSNFMLFY 340
Cdd:MTH00070 327 LTIILSLMLLPITPTILNLF 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-295 3.89e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 180.81  E-value: 3.89e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMMWWD 87
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  88 NK---NIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAP---MMTMSYCIKMsSFLFVVIMMGIIVG 161
Cdd:MTH00105  87 TKltnPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPlsiLYQISPSINP-NLLLTLAILSILIG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 162 AMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMMM 241
Cdd:MTH00105 166 GWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLIL 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 317097458 242 TSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFS 295
Cdd:MTH00105 246 LTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYS 299
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-332 5.53e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 180.08  E-value: 5.53e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   5 SMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMM 84
Cdd:MTH00144   4 PSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  85 WWdnkniPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGI---IVG 161
Cdd:MTH00144  84 WF-----SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVlsaLVG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 162 AMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEiKFMMM 241
Cdd:MTH00144 159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKT-GLSII 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 242 TSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVMALPI 321
Cdd:MTH00144 238 SLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISLNL 317

                        330
                 ....*....|.
gi 317097458 322 LSMISTMGLIC 332
Cdd:MTH00144 318 LGGLLFLLLYL 328
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-339 1.50e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 168.99  E-value: 1.50e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   6 MKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMMW 85
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  86 WDNK---NIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAP--MMTMSYCIKMSSFLFVVIMMGIIV 160
Cdd:MTH00200  85 GISEmlgPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPfaLLIQLAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 161 GAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMM 240
Cdd:MTH00200 165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 241 MTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAII-----MLHNENSWLTSIKMNKL 315
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLtlspnQINMMSSWRTKSNSNLL 324

                        330       340
                 ....*....|....*....|....
gi 317097458 316 VMalpILSMISTMGLICTSNFMLF 339
Cdd:MTH00200 325 VG---LLLLLSILGLPLTPQLLFL 345
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-330 4.32e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 164.98  E-value: 4.32e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   9 LFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISIL----------II 78
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  79 QMKYMmwwdnknIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVI-MMG 157
Cdd:MTH00135  88 QMSHP-------LPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLgLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 158 IIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIySASYFKTEI- 236
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTL-ATSWTKAPAl 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 237 KFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFS-AIIMLHNENSWLTSIKMNKL 315
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAmTLTISPNTLNGTTPWRLPST 319

                        330
                 ....*....|....*.
gi 317097458 316 VMALPI-LSMISTMGL 330
Cdd:MTH00135 320 QLTLPLaISTTATLML 335
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-328 8.04e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 163.69  E-value: 8.04e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   9 LFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMMwwdn 88
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  89 KNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGIIVGAMGGLNQ 168
Cdd:MTH00197  78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 169 TSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMMMTSLLSLG 248
Cdd:MTH00197 158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 249 GLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVMALPILSMISTM 328
Cdd:MTH00197 238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMMLPLL 317
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 8-302 1.21e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 160.72  E-value: 1.21e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMMwwd 87
Cdd:MTH00011   9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSL--- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  88 NKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYC--IKMSSFLFVVIMMGIIVGAMGG 165
Cdd:MTH00011  86 LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALAGGLGG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 166 LNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMMMTSLL 245
Cdd:MTH00011 166 MNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLL 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 317097458 246 SLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHN 302
Cdd:MTH00011 246 SLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPT 302
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 4.69e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 96.34  E-value: 4.69e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSSLmmGTILSISSNSWLGIWMGLEinLLSI-----IPMLTDNKNSmiNEPAIKYFIIQSMASTMLL--ISIL---- 76
Cdd:COG1007  107 LLLFATL--GMMLMASANDLLTLFLGLE--LLSLslyvlVAFRRDDRRS--SEAALKYFLLGALSSGFLLygISLLygat 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  77 ----IIQMKYMMWWDNKNIPSMMIMSSMMMK-----MGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPM---------M 138
Cdd:COG1007  181 gslnLAGIAAALAAGGANSPLLLLGLVLVLAglafkLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveA 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 139 TMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWM-ISSMTISENTWE---FYFLIYSTLNV----I 210
Cdd:COG1007  261 FPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafaV 340

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 211 IIFM----FKTMNLFFLNQIYSASYFKTeikFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITL 286
Cdd:COG1007  341 ILLLsrkgGEAEEIEDLAGLARRSPLLA---LAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISA 417


                 ....*.
gi 317097458 287 YYYMRI 292
Cdd:COG1007  418 YYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-277 4.67e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.52  E-value: 4.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   24 SNSWLGIWMGLEINLLSIIPMLTDNKNSMI-NEPAIKYFIIQSMASTMLLISILII--------------QMKYMMWWDN 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRsSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   89 KNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSW-INCLMLMTWQKIAPMMTM-------SYCIKMSSFLFVVIMMGIIV 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  161 GAMGGLNQTSLRQILAYSSISHLGWMISSM----TISENTWEFYFLIYSTLNVIIIFMF-----KTMNLFFLNQIYSASY 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAgsviyRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 317097458  232 FKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLL 277
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-312 4.75e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 89.70  E-value: 4.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  16 MGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMIN-EPAIKYFIIQSMASTMLL------------ISILIIQMKY 82
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLfgcallcgttggLHLSYINLVL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  83 MMWWDNKN----IPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGI 158
Cdd:MTH00196  84 NSGQSFSSvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 159 IVGAMGGLNQTSLRQILAYSSISHLGWMISSMTI----SENTWEFYFLIYSTLNVIIIFMFKTMNlFFLNQIYSASYFKT 234
Cdd:MTH00196 164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSICVFSIILALN-VYKNLIIEFSGLSR 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 235 EIKFMMMT---SLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRIsfSAIIMLHNENSWLTSIK 311
Cdd:MTH00196 243 RLPILAITlalTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI--VKILFFQANSFLLISTK 320


                 .
gi 317097458 312 M 312
Cdd:MTH00196 321 I 321
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-292 3.35e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.95  E-value: 3.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSSLMmGTILSISSNSWLGIWMGLEINLLS---IIPMLTDNKNSmiNEPAIKYFIIQSMASTMLLI----------S 74
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPlyaLAALRRDRRRS--LEAAIKYFVLGALASGFLLYgmsllygatgS 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  75 ILIIQMKYMMWWDNKNIPSMMIMSSMMMK-----MGAAPFHFWLPEV-----------MSSTSWINCLMLMTwqKIAPMM 138
Cdd:PRK05777 184 LSFAGIAKALADGSGNSLLLLFGLVFLLVglafkLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVA 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 139 TMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWM----ISSMTISENTWEFYFLIYSTLNV----I 210
Cdd:PRK05777 262 FGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglAAGTAEGYSAVLFYLLAYLFMTLgafgV 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 211 IIFM----FKTMNLFFLNQIYSASYFKTeikFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITL 286
Cdd:PRK05777 342 ISLLrrkgGEAESISDFAGLSKRSPLLA---AVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGA 418


                 ....*.
gi 317097458 287 YYYMRI 292
Cdd:PRK05777 419 FYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-338 1.51e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.07  E-value: 1.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   17 GTILSISSNSWLGIWMGLEI-NLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLL---------------ISILIIQM 80
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELqSLCFYVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLfgisliygftgslnfEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   81 KYMMWWDNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIA---PMMTMSYCI------KMSSFLF 151
Cdd:TIGR01770 194 NGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYIlfgfseAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  152 VVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISEntwefYFLIYSTLNVIIIFMFKTMNLF---------- 221
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGT-----LEGIKAVLFYIFIYALMSLGAFgvlsllrsyk 348

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  222 -----FLNQIYSASYFKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRIsfSA 296
Cdd:TIGR01770 349 dewieYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV--VK 426

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 317097458  297 IIMLHNENSWLTSIKMNKLVMALPILSMISTMGLICTSNFML 338
Cdd:TIGR01770 427 VMYFDKPERRIPSNPQSKAQSLLLSISALFILFLGLFPSLIL 468
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 1.62e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 74.03  E-value: 1.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  10 FLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQ-------MKY 82
Cdd:COG0651  112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYgatgtlnMAD 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  83 MMWWDNKNIPSMMIMSSMMMKMG------AAPFHFWLPEVMSST-SWINCLM--LMTwqKIA---------PMMTMSYCI 144
Cdd:COG0651  192 LAARLAELDPGLLLAAFALLLVGfgikaaLFPLHFWLPDAYPAApSPVSALLsgLLT--KVGvyailrvltLLFGADPAL 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 145 KMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWM---ISSMTISENTWEFYFLIYSTLNVIIIFM------- 214
Cdd:COG0651  270 FLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYIllgLGLGTPLGLAGALFHLLNHALAKALLFLaagaier 349

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 317097458 215 -FKTMNLFFLNQIYSASYFkteIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRI 292
Cdd:COG0651  350 aTGTRDLDKLGGLGKRMPL---TAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 2.09e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 73.90  E-value: 2.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  16 MGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMIN-EPAIKYFIIQSMASTMLLISIL----------IIQMKYMM 84
Cdd:MTH00199 108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCAllygltgetsIQGINSIL 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  85 wwdNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGIIVGAMG 164
Cdd:MTH00199 188 ---TGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 165 GLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYstlnvIIIFMFKTMNLFFL--------NQIYSASYFKTEI 236
Cdd:MTH00199 265 ALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIY-----MIIYVIMSICSFSIilslkltkGLIVEVSGLSRKN 339

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 317097458 237 KFMMMT---SLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRI 292
Cdd:MTH00199 340 PVIALTlalTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-292 5.65e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.50  E-value: 5.65e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  16 MGTILSISSNSWLGIWMGLEINLLSIIPM---------LTDNKNSMINEPAIKYFIIQSMASTMLLI------------- 73
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgneg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  74 ---SILIIQMKYM-MWWDNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSF 149
Cdd:MTH00198 279 mlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 150 LFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMIssMTISENTWE------FYFLIYSTLNVIIIFMFKTMNLFfl 223
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL--IGVSAGTYEslqaswTYAVTYLVSALASFTVICTLEEF-- 434

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 224 NQIYSASYFKTE-----------------------IKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTA------- 273
Cdd:MTH00198 435 GTRTPTSRQRDGsfgnynlvrrlvdltilsrgqpyIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSslsiyyl 514

                        330
                 ....*....|....*....
gi 317097458 274 LVLLMITFTTITLYYYMRI 292
Cdd:MTH00198 515 VALFAIICTCISAFYYIRI 533
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
149-292 7.63e-10

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 60.06  E-value: 7.63e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 149 FLFVVI-MMGIIVGAMGGLNQTSLRQILAYSSISHLGW-MISSMTISENTWE---FYFLIYSTLNV-----IIIFMFKTM 218
Cdd:PRK02504 277 LLFTALaILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvMIGLVAGTEAGYAsmvFYLLAYLFMNLgafacVILFSLRTG 356

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 317097458 219 NlfflNQI--YSASYFKTE-IKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRI 292
Cdd:PRK02504 357 T----DQIsdYAGLYQKDPlLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 105-292 4.09e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 54.50  E-value: 4.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 105 GAAPFHFWLPEVMSSTSWINCLML----------MTWQKIAPMMTMSYCIKMS--SFLFVVIMMGIIVGAMGGLNQTSLR 172
Cdd:PRK08375 217 AVFPLHTWLPRAYPAAPPVVTALLsglvtkvavyALIRIYFTVFGGDFRFALGlgWLLAVLALLSMLVGSLAALGQDDVK 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 173 QILAYSSISHLGWMISSMTISENTWEFYFLIYstlnvIIIFMFKTMNLFFLNQIYSASYFKTEIKFM---------MMTS 243
Cdd:PRK08375 297 RVLAYSTVSQMGYILLGLALLTPLALAAGLLH-----LLHHALMKGALFLAAGAIEVTYGTRRLSELsglgrrmplTAAA 371

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 317097458 244 ----LLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRI 292
Cdd:PRK08375 372 favaSLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
158-296 8.50e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.42  E-value: 8.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 158 IIVGAMGGLNQTSLRQILAYSSISHLGWMI---SSMTISENTWEFYFLIYSTLNV--------IIIFMFKTMNLFFLNQI 226
Cdd:PRK12663 283 MVIGALGALAYKDIRRIAGYQVISSIGFILlglALGTPAGINGAIFYLVHDMVVKtalfliagSLVRLTGYRSLQYLGGL 362

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 227 YSASYFKTEIKFMMmtsLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSA 296
Cdd:PRK12663 363 YRKEPLFGALFLIL---IFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFLA 429
ndhB CHL00049
NADH dehydrogenase subunit 2
 106-333 4.43e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 51.16  E-value: 4.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 106 AAPFHFWLPEV-----------MSSTSWINCLMLMTwqKIAPMMTMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQI 174
Cdd:CHL00049 230 LAPFHQWTPDVyegsptpvvafLSVTSKVAASALAT--RIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRM 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 175 LAYSSISHLGWMISSMTISENTWEF-----YFLIYSTLNV-----IIIFMFKTMNlfflNQI--YSASYFKTEI-KFMMM 241
Cdd:CHL00049 308 LAYSSIGQIGYVIIGIIVGDSNDGYasmitYMLFYIFMNLgtfacIVLFGLRTGT----DNIrdYAGLYTKDPFlALSLA 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 242 TSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRIsfsAIIMLHNENSWLTSIKMNKLVMALPI 321
Cdd:CHL00049 384 LCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI---IKLLMTGRNQEITPYVRNYRRSPLRS 460

                        250
                 ....*....|..
gi 317097458 322 LSMISTMGLICT 333
Cdd:CHL00049 461 NNSIELSMIVCV 472
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 108-298 1.16e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 49.97  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 108 PFHFWLPEVMSST-SWINCLM--LMTWQKIAPMMTMSYCI---------KMSSFLFVVIMMG---IIVGAMGGLNQTSLR 172
Cdd:PRK12667 241 PNHFWLPDAHPAApSPVSAMLsgLVVNVGAYAIIRFLYTIfgispslidFRAALSPILIILGavsAIIGALMMVVQKDVK 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 173 QILAYSSISHLGWMIssMTISENTwefYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIK-------------FM 239
Cdd:PRK12667 321 RLLAYSTISHMGYIF--MGIGIGT---QLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDIDelaglgrkmpiasFA 395

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 317097458 240 MMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAII 298
Cdd:PRK12667 396 FLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLFF 454
PRK12650 PRK12650
DUF4040 family protein;
108-298 2.65e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 49.27  E-value: 2.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 108 PFHFWLPEVMSSTSWINC-LMLMTWQKIAPMMTMSYCIKMSS------FLFVVIMMGIIVGAMGGLNQTSLRQILAYSSI 180
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAfLHAAAVVKAGIYLLLRFSPVFHDvavwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 181 SHLGWMISsmTISENTweFYFLIYSTLNVIIIFMFKTmNLFFLNQI------------YSASYFKTEIKFMMMT-SLLSL 247
Cdd:PRK12650 306 SQLGWIVA--TIGVGT--PFALTAAVVHTLAHALFKS-SLFMLIGVvdhqagtrdirrLGSLWRRMPFTFVSVTiAALSM 380

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 317097458 248 GGLPPFLGFLPKWIVMQSL----IDNKMTALVLLMITFTTI-TLYYYMRISFSAII 298
Cdd:PRK12650 381 AAVPPLFGFVSKEGMLTAFleapGGNAGVVLLLVGAALGAVfTFAYSARLVLGAFV 436
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-296 1.26e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.63  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  55 EPAIKYFIIQSMASTMLLISI--------------LIIQMKYMMWWDNKnIPSMMIMSSMMMKMGAAPFHFWLPEVMSST 120
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGIallygqygtlnmayLAVKMSENPTVVAK-IALALFIAGLAMKSGAVPVHMWLPDAYPAA 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 121 -SWINCLMLMTWQ-KIAPMMTMSYCI-----KMSSFLFVVIMMG---IIVGAMGGLNQTSLRQILAYSSISHLGWMISSM 190
Cdd:PRK08376 251 pSSISAMLLVIKQaGLYALARVLFSIygpaiNLATVGWVIIILGcltMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGL 330

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 191 TISENTWEFYFL-----------IYSTLNVIII--FMFKTMNLFF-------LNQIYSASYFKTEIKFMMMTSLLSLGGL 250
Cdd:PRK08376 331 GVGLAALGDPAMasygeialaggIYHIVNHALYkaLLFLTAGAVIyetgtrnLNELGGLARTMPKTTIAFLIGAAAIVGL 410

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 317097458 251 PPFLGFLPKWIVMQSLIDNKMTALVLLMITfTTITLYYYMRISFSA 296
Cdd:PRK08376 411 PPFNGFASKWLIYESSALFNPILGVIAMIG-SVLTLASFVKVFHTA 455
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 108-294 4.98e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 41.68  E-value: 4.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 108 PFHFWLPEVM-----------SSTswinclM------LMTwqKIAPMMTMSycikmSSFLFVVIMMG---IIVGAMGGLN 167
Cdd:COG1009  229 PLHFWLPDAMegptpvsallhAAT------MvkagvyLLA--RLSPLFALS-----PVWLTVVAIIGaitALFAALIALA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 168 QTSLRQILAYSSISHLGWMISSMTISenTWE---FYFLIYST------LNV-IIIFMFKTMNLFFLNQIYsasyfkteiK 237
Cdd:COG1009  296 QTDIKRVLAYSTVSQLGYMFLALGVG--AYVaalFHLLTHAFfkallfLGAgSVIHATGTRDIRKMGGLR---------K 364

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 317097458 238 FM------MMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTT--ITLYYYMRISF 294
Cdd:COG1009  365 KMpitaitFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALLGafLTAFYSFRLFF 429
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 146-265 2.58e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 39.57  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 146 MSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMIssMTISENTWE------FY----FLIYSTLNVIIIFMF 215
Cdd:PRK12665 272 LDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMV--FGIALSTVAglsgaiYYvahhITVQTTLFLVVGLIE 349

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 317097458 216 KTMNLFFLNQIYSASYFKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQS 265
Cdd:PRK12665 350 RQAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEA 399
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 3-324 2.75e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 39.59  E-value: 2.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   3 NNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLS---IIPMltDNKNSmiNEPAIKYFIIQSMASTMLLISILIIQ 79
Cdd:PRK08668  96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSsfmMVPM--GKKES--RKASLKYFVLSAIGAYAMLYAIFLIY 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  80 MKY----------MMWWDNKN----IPSMMIMSSMMMKMGAAPFHFWLPEVMSSTS-------------------WINCL 126
Cdd:PRK08668 172 AKTgtfdfadisqGLINDTSTgfalIVFLFLLAFGVAKAGIFPLHVWAPDAYSEAPqsfsavlsgqlsklgaygfLLVLY 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 127 MLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISENtwefYFLIYST 206
Cdd:PRK08668 252 VLPGTKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTS----LGFAGGL 327

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 207 LNVIIIFMFKTMnlFFLnqIYSASYF---KTEIK-------------FMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNK 270
Cdd:PRK08668 328 FHVFNHALFKGL--FFL--IFAAVIYrtgTTKISemggliekmpftfAMYLVAIISLAGIPPMSGFASKWLIFEALISKG 403

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 317097458 271 MtALVLLMITFTTITLYYYMrISFSAIIMLHNENSWLTSIKMNKLVMALPILSM 324
Cdd:PRK08668 404 M-PITAFMAFFGSIGSFLYV-FRPLAGVFLGQLPSDHKDVKEAPLPMLIPMAIL 455
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-340 2.79e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 39.41  E-value: 2.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   3 NNSMKLLFLSSLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTML-LISILIIQMK 81
Cdd:PRK06589 114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLfLPAVILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  82 Y--------MMWWDNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLM---------LMTWQKIAPMM----TM 140
Cdd:PRK06589 194 TgnldfvsgGLFSKNQSIILLLMFIYGIAKTAIFPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 141 SYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTI----SENTWEFYFLIYSTLNVIIIFMFK 216
Cdd:PRK06589 274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFAKICLFYSMG 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 217 TMNLF----FLNQIYSASYFKTEIKFMMMTSLLSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLM----ITFTTITLYY 288
Cdd:PRK06589 354 SIYSLkkedQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVmlvvIASSILSALY 433

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 317097458 289 YMRISFSAIIMLHNENSWLTSIkmnklvmaLPILSMISTMGLICTSNFMLFY 340
Cdd:PRK06589 434 LLKILSSIYKPSLSENSFITKS--------LPYLMQISVITCCCALTLFYFI 477
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 105-295 5.51e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.58  E-value: 5.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 105 GAAPFHFWLPEVMS-STSWINCLMLMTWQKI---------APMMTMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQI 174
Cdd:PRK08676 221 GLVPFHTWLPAAYAkAPSVVSALLSGTVLNIgiygilrlsALLRQSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKL 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 175 LAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIifmfkTMNLFFLNQIYSASYFKTEIKFM-------------MM 241
Cdd:PRK08676 301 IAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLV-----KSGLFFSAGILHRQYRSDRFDRIfdvfrlqpvaawgVI 375

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 317097458 242 TSLLSLGGLPPFLGFLPKWIVMQSL--IDNKMTALVLLMITFTTITLYYYMRISFS 295
Cdd:PRK08676 376 LGSAAIIGMPPFPLFLSKFFILLQLggISVWLVLAVLLLLLLAASSFAIFLLKAFT 431
PRK12646 PRK12646
DUF4040 family protein;
108-190 5.67e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 38.58  E-value: 5.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 108 PFHFWLPEVMSSTSWINCLM---------LMTWQKIAPMMTMSycikmSSFLFVVIMMGII---VGAMGGLNQTSLRQIL 175
Cdd:PRK12646 228 PFHIWLPRAMAAPTPVSAYLhsatmvkagIFLLFRFTPLLGLS-----NMYIYIVTFVGLItmlFGSITALKQWDLKGIL 302

                         90
                 ....*....|....*
gi 317097458 176 AYSSISHLGwMISSM 190
Cdd:PRK12646 303 AYSTISQLG-MIMAM 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 57-187 5.99e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 38.38  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   57 AIKYFIIQSMASTMLLISILIIQMKYMMWWD-----NKNIPSMMIMSSMMMKMGA-------APFHFWLPEVMSSTSWIN 124
Cdd:TIGR01972 158 AMKFFLYTLAGSLLMLLAILGLYFLGGGTFDllellNLPLPFGVQTWLFLAFFIAfavkvplFPLHTWLPDAHVEAPTAG 237

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 317097458  125 CLMLM-TWQKIAPMMTMSYCIKM--------SSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMI 187
Cdd:TIGR01972 238 SVILAgVLLKMGTYGFLRFNLPLfpdaslyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 8-292 9.48e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 37.82  E-value: 9.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458   8 LLFLSsLMMGTILSISSNSWLGIWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILII-------QM 80
Cdd:PRK08377 112 MLFLL-LMLGATGMIATGDIFNLFVFMEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIGVALIygatgtlNM 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  81 KYMMWWDNKNIPSMMIMSSMMMKMGAA------PFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKM-------S 147
Cdd:PRK08377 191 AHIAQLAGTIDPTVAQVGLALLIFGLAveaelfPLNAWAPDAYQAAPHPITVMFSAFVVKAGLYAMARILYLmqnangwS 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 148 SFLFVVIMMG---IIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTW---EFYFLIYSTLNVIIIFMFKTMNLF 221
Cdd:PRK08377 271 SVLKLVIIMAtltVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGvdaGVFHMINHAIVKALLFLAVGYVGI 350

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 317097458 222 FLNQIySASYFKTEIKFMMMTSL------LSLGGLPPFLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRI 292
Cdd:PRK08377 351 TLGGT-EIEKFEGLGKRMPLTALaltigaLSTVGIPLFNVFWSKFRIILAGLSAGYTWPVALVLGASVVEAVYYFRL 426
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
55-325 9.50e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 37.70  E-value: 9.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  55 EPAIKYFIIQSMASTMLLISIL----------IIQMKYMMWWDNKNIPSMMIMSSMMM----KMGAAPFHFWLPEVMSST 120
Cdd:PRK06277 150 KAALKYMILGNVAGSILLLGIGfllastgtlnITDIHNALLVNPTSPVIYGGLLLLIFgllyGSGLPPFHTIKSDIYAKA 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 121 SWINCLMLMTWQKIAPMMTMSYCIKM----------SSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSM 190
Cdd:PRK06277 230 KPFGSALLQTFSKFVLVALMLVIFKLfgglsyfpsaQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGL 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458 191 TISeNTWEFYFLIYSTLNVIII--FMFKTMNLFF-------LNQIYSASYFKTEIKFMMMTSLLSLGGLPPFLGFLPKWI 261
Cdd:PRK06277 310 ALG-TPLGIVAGIFHAINHVIYksALFLGAGIVSyrtktsnLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLM 388

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 317097458 262 VMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKL-VMALPILSMI 325
Cdd:PRK06277 389 LAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYLKPKPEELEYKNKKVPKYaVFSLAVLTIL 453
2a6301s01 TIGR00940
Tmonovalent cation:proton antiporter; This family of proteins constists of bacterial ...
 108-259 9.86e-03

Tmonovalent cation:proton antiporter; This family of proteins constists of bacterial multicomponent K+:H+ and Na+:H+ antiporters. The best characterized systems are the PhaABCDEFG system of Rhizobium meliloti which functions in pH adaptation and as a K+ efflux system and the MnhABCDEFG system of Staphylococcus aureus which functions as a Na+:H+ antiporter. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273353 [Multi-domain]  Cd Length: 793  Bit Score: 37.90  E-value: 9.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  108 PFHFWLPEVMSSTSWINCLM---------LMTWQKIAPMMTMSycikmSSFLFVVIMMGIIV---GAMGGLNQTSLRQIL 175
Cdd:TIGR00940 224 PFHIWLPDAMEAPTPVSAYLhsatmvkagLYLLARFTPVFAGT-----EAWFWIVGLAGLITllwGSYFAIFQQDLKGIL 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 317097458  176 AYSSISHLGWMISSMTISENTWEFY---FLIYSTLNVIIIF------MFKTmNLFFLNQIYSASYFKTEIK-------FM 239
Cdd:TIGR00940 299 AFSTISQLGLIMVLLGLGSPSYHYQgddSKIYALAAVAAVFhlinhaTFKG-SLFMAAGIIDHETGTRDIRklgglfhIM 377

                         170       180
                  ....*....|....*....|....*.
gi 317097458  240 ------MMTSLLSLGGLPPFLGFLPK 259
Cdd:TIGR00940 378 pitftlAMIASAAMAGVPPFNGFLSK 403
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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