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Conserved domains on  [gi|31621309|ref|NP_036604|]
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dynein axonemal assembly factor 11 isoform a [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1903219)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 23-155 1.24e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 90.23  E-value: 1.24e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  23 LEELSLHQQEIERLEHIDKwCRDLKILYLQNNLIGKIENVSKLKKLE------------------------------YLN 72
Cdd:cd21340  48 LTHLYLQNNQIEKIENLEN-LVNLKKLYLGGNRISVVEGLENLTNLEelhienqrlppgekltfdprslaalsnslrVLN 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  73 LALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKN-LQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIE 151
Cdd:cd21340 127 ISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEIT 206


                ....
gi 31621309 152 PSER 155
Cdd:cd21340 207 DTER 210
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 23-155 1.24e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 90.23  E-value: 1.24e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  23 LEELSLHQQEIERLEHIDKwCRDLKILYLQNNLIGKIENVSKLKKLE------------------------------YLN 72
Cdd:cd21340  48 LTHLYLQNNQIEKIENLEN-LVNLKKLYLGGNRISVVEGLENLTNLEelhienqrlppgekltfdprslaalsnslrVLN 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  73 LALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKN-LQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIE 151
Cdd:cd21340 127 ISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEIT 206


                ....
gi 31621309 152 PSER 155
Cdd:cd21340 207 DTER 210
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
22-146 1.46e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 1.46e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  22 SLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKI-ENVSKLKKLEYLNLALNNIEKI-ENLEGCEELAKLDLTVNF 99
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQ 193

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 31621309 100 IGELS-SIKNLQhniHLKELFLMGNPCASFDHyrefVVATLPQLKWLD 146
Cdd:COG4886 194 ITDLPePLGNLT---NLEELDLSGNQLTDLPE----PLANLTNLETLD 234
LRR_9 pfam14580
Leucine-rich repeat;
1-160 8.56e-09

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 54.77  E-value: 8.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309     1 MGWITEDLIRRNAEHNDCVifSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEK 80
Cdd:pfam14580   1 MVKLTAELIEQSAQYTNPV--RERELDLRGYKIPIIENLGATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309    81 IEnlEGCEE----LAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERI 156
Cdd:pfam14580  79 IG--EGLGEalpnLTELILTNNNLQELGDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQ 156


                  ....
gi 31621309   157 KALQ 160
Cdd:pfam14580 157 AAEK 160
LRRcap smart00446
occurring C-terminal to leucine-rich repeats; A motif occurring C-terminal to leucine-rich ...
 128-146 2.73e-04

occurring C-terminal to leucine-rich repeats; A motif occurring C-terminal to leucine-rich repeats in "sds22-like" and "typical" LRR-containing proteins.


Pssm-ID: 197729  Cd Length: 19  Bit Score: 38.06  E-value: 2.73e-04
                           10
                   ....*....|....*....
gi 31621309    128 FDHYREFVVATLPQLKWLD 146
Cdd:smart00446   1 LAHYREKVIELLPQLRKLD 19
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 23-155 1.24e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 90.23  E-value: 1.24e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  23 LEELSLHQQEIERLEHIDKwCRDLKILYLQNNLIGKIENVSKLKKLE------------------------------YLN 72
Cdd:cd21340  48 LTHLYLQNNQIEKIENLEN-LVNLKKLYLGGNRISVVEGLENLTNLEelhienqrlppgekltfdprslaalsnslrVLN 126

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  73 LALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKN-LQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIE 151
Cdd:cd21340 127 ISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDlLSSWPSLRELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEIT 206


                ....
gi 31621309 152 PSER 155
Cdd:cd21340 207 DTER 210
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
22-146 1.46e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.03  E-value: 1.46e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  22 SLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKI-ENVSKLKKLEYLNLALNNIEKI-ENLEGCEELAKLDLTVNF 99
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSNNQ 193

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 31621309 100 IGELS-SIKNLQhniHLKELFLMGNPCASFDHyrefVVATLPQLKWLD 146
Cdd:COG4886 194 ITDLPePLGNLT---NLEELDLSGNQLTDLPE----PLANLTNLETLD 234
LRR_9 pfam14580
Leucine-rich repeat;
1-160 8.56e-09

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 54.77  E-value: 8.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309     1 MGWITEDLIRRNAEHNDCVifSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEK 80
Cdd:pfam14580   1 MVKLTAELIEQSAQYTNPV--RERELDLRGYKIPIIENLGATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309    81 IEnlEGCEE----LAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERI 156
Cdd:pfam14580  79 IG--EGLGEalpnLTELILTNNNLQELGDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQ 156


                  ....
gi 31621309   157 KALQ 160
Cdd:pfam14580 157 AAEK 160
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
22-160 1.96e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.10  E-value: 1.96e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  22 SLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIG 101
Cdd:COG4886 206 NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLT 285

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 31621309 102 ELsSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQ 160
Cdd:COG4886 286 DL-KLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 46-86 2.43e-06

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 44.16  E-value: 2.43e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 31621309    46 LKILYLQNNLIGKIENVSKLKKLEYLNLALNN-IEKIENLEG 86
Cdd:pfam12799   3 LEVLDLSNNQITDIPPLAKLPNLETLDLSGNNkITDLSDLAN 44
LRR_8 pfam13855
Leucine rich repeat;
46-98 9.60e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 9.60e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 31621309    46 LKILYLQNNLIGKIENVS--KLKKLEYLNLALNNIEKIEN--LEGCEELAKLDLTVN 98
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfkGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGN 59
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
46-146 1.44e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.24  E-value: 1.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  46 LKILYLQNNligkiENVSKLKKLEYLNLALNNIEKI-ENLEGCEELAKLDLTVNFIGEL-SSIKNLQhniHLKELFLMGN 123
Cdd:COG4886  98 LTELDLSGN-----EELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLT---NLKSLDLSNN 169

                        90       100
                ....*....|....*....|...
gi 31621309 124 PCASFDHyrefVVATLPQLKWLD 146
Cdd:COG4886 170 QLTDLPE----ELGNLTNLKELD 188
LRRcap smart00446
occurring C-terminal to leucine-rich repeats; A motif occurring C-terminal to leucine-rich ...
 128-146 2.73e-04

occurring C-terminal to leucine-rich repeats; A motif occurring C-terminal to leucine-rich repeats in "sds22-like" and "typical" LRR-containing proteins.


Pssm-ID: 197729  Cd Length: 19  Bit Score: 38.06  E-value: 2.73e-04
                           10
                   ....*....|....*....
gi 31621309    128 FDHYREFVVATLPQLKWLD 146
Cdd:smart00446   1 LAHYREKVIELLPQLRKLD 19
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 65-123 6.17e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 6.17e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 31621309  65 LKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIgelSSIKNLQHNIHLKELFLMGN 123
Cdd:cd21340   1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKI---TKIENLEFLTNLTHLYLQNN 56
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 66-108 7.05e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 37.22  E-value: 7.05e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 31621309    66 KKLEYLNLALNNIEKIENLEGCEELAKLDLT-VNFIGELSSIKN 108
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLAN 44
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 46-124 9.47e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 41.31  E-value: 9.47e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  46 LKILYLQNNLIGK------IENVSKLKKLEYLNLALNNI------EKIENLEGCEELAKLDLTVNFIGELSSI---KNLQ 110
Cdd:COG5238 210 VTTLWLKRNPIGDegaeilAEALKGNKSLTTLDLSNNQIgdegviALAEALKNNTTVETLYLSGNQIGAEGAIalaKALQ 289

                        90
                ....*....|....
gi 31621309 111 HNIHLKELFLMGNP 124
Cdd:COG5238 290 GNTTLTSLDLSVNR 303
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 49-124 1.01e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 41.31  E-value: 1.01e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  49 LYLQNNLIGK------IENVSKLKKLEYLNLALNNI------EKIENLEGCEELAKLDLTVNFIGELSSI---KNLQHNI 113
Cdd:COG5238 269 LYLSGNQIGAegaialAKALQGNTTLTSLDLSVNRIgdegaiALAEGLQGNKTLHTLNLAYNGIGAQGAIalaKALQENT 348

                        90
                ....*....|.
gi 31621309 114 HLKELFLMGNP 124
Cdd:COG5238 349 TLHSLDLSDNQ 359
LRR_8 pfam13855
Leucine rich repeat;
22-78 2.85e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 2.85e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31621309    22 SLEELSLHQQEIERLEhiDKW---CRDLKILYLQNNLIGKIENVS--KLKKLEYLNLALNNI 78
Cdd:pfam13855   2 NLRSLDLSNNRLTSLD--DGAfkgLSNLKVLDLSNNLLTTLSPGAfsGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 20-194 4.17e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 39.26  E-value: 4.17e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  20 IFSLEELSLHQQEIERlEHIDKWCR-------DLKILYLQNNLIGK------IENVSKLKKLEYLNLALNNI--EKIENL 84
Cdd:cd00116 107 SSSLQELKLNNNGLGD-RGLRLLAKglkdlppALEKLVLGRNRLEGascealAKALRANRDLKELNLANNGIgdAGIRAL 185

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31621309  85 egCEELA------KLDLTVNFIGELSSIK---NLQHNIHLKELFLMGNPCASFD--HYREFVVATLPQLK--WLDGKEIE 151
Cdd:cd00116 186 --AEGLKancnleVLDLNNNGLTDEGASAlaeTLASLKSLEVLNLGDNNLTDAGaaALASALLSPNISLLtlSLSCNDIT 263

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 31621309 152 PSERIKALQdysVIEPQIREQEKDhcLKRAKLKEEAQRKHQEE 194
Cdd:cd00116 264 DDGAKDLAE---VLAEKESLLELD--LRGNKFGEEGAQLLAES 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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