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Conserved domains on  [gi|312839598|gb|ADR01732|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Brochis splendens]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-220 1.01e-118

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00127:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 459  Bit Score: 345.40  E-value: 1.01e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00127 239 LGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMI 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00127 319 AHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTG 398

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00127 399 LGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWGW 458
 
Name Accession Description Interval E-value
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-220 1.01e-118

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 345.40  E-value: 1.01e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00127 239 LGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMI 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00127 319 AHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTG 398

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00127 399 LGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWGW 458
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-210 1.16e-43

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 152.54  E-value: 1.16e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPL-SKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:COG1008  254 MGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQM 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:COG1008  334 VSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILA 413

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 312839598 160 GTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIML 210
Cdd:COG1008  414 ALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLL 464
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-154 1.73e-37

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 132.05  E-value: 1.73e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598    1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:pfam00361 127 AGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLL 206

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 312839598   81 AHGLVSSALFCLA-NTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:pfam00361 207 THGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-210 4.11e-37

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 134.68  E-value: 4.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598    1 LGGYGMMRMMIMLDP-LSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:TIGR01972 248 MGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQM 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:TIGR01972 328 ISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLA 407

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 312839598  160 GTGTLITAAYSLYLFLKTQRGTLP-THIINLQPYHTREHLLMALHLLPVIML 210
Cdd:TIGR01972 408 ALGIVLAAAYMLTLYKRVFFGELSnPEVAEFPDLNGREIAVLAPLVVLILFL 459
 
Name Accession Description Interval E-value
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-220 1.01e-118

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 345.40  E-value: 1.01e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00127 239 LGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALILMI 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00127 319 AHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLALTG 398

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00127 399 LGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWGW 458
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-220 6.36e-115

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 335.63  E-value: 6.36e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00124 238 LGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMILMI 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00124 318 AHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTIILTG 397

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00124 398 LATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-220 1.05e-112

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 329.95  E-value: 1.05e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00068 238 LGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAIILMI 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00068 318 SHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTILITG 397

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00068 398 LGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGM 457
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-219 3.12e-104

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 308.36  E-value: 3.12e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00110 238 LGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATALMI 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00110 318 AHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITIILMG 397

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWG 219
Cdd:MTH00110 398 LNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILG 456
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-217 7.80e-91

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 273.74  E-value: 7.80e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00206 234 LGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALLLMI 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00206 314 AHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLPLLG 393

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELM 217
Cdd:MTH00206 394 LGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-217 4.59e-79

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 244.11  E-value: 4.59e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMM-IMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:MTH00044 239 LGGYGLIRLInLFSLPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGALILM 318

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:MTH00044 319 IAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILSFPII 398

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 312839598 160 GTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELM 217
Cdd:MTH00044 399 GLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNII 456
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-220 2.81e-63

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 201.99  E-value: 2.81e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00150 197 LGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGALIMMV 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00150 277 SHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFFVPLG 356

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00150 357 LMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLFMW 416
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-220 1.91e-62

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 200.77  E-value: 1.91e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00163 226 LGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLLMMI 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00163 306 GHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMIFLM 385

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00163 386 LLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLFMLW 445
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-220 1.10e-58

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 191.11  E-value: 1.10e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00014 232 LGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGALAMMI 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00014 312 AHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAILLA 391

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:MTH00014 392 ITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLITNW 451
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-216 5.82e-53

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 176.32  E-value: 5.82e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00205 230 LGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAIIMMV 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00205 310 AHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGIPLS 389

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 312839598 161 TGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPEL 216
Cdd:MTH00205 390 LISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKI 445
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-210 1.16e-43

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 152.54  E-value: 1.16e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPL-SKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:COG1008  254 MGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAVLQM 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:COG1008  334 VSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILA 413

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 312839598 160 GTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIML 210
Cdd:COG1008  414 ALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLL 464
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-210 5.46e-38

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 137.26  E-value: 5.46e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPL-SKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:PRK05846 256 MGAYGLLRFSLPLFPDaSHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGAIFQM 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:PRK05846 336 ISHGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVIAFIA 415

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 312839598 160 GTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIML 210
Cdd:PRK05846 416 TTGLILAAVYSLWLYQRVMFGPVKNEVAKLKDLNGRELLILLPLVALLLLL 466
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-154 1.73e-37

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 132.05  E-value: 1.73e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598    1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:pfam00361 127 AGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLL 206

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 312839598   81 AHGLVSSALFCLA-NTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:pfam00361 207 THGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-210 4.11e-37

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 134.68  E-value: 4.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598    1 LGGYGMMRMMIMLDP-LSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:TIGR01972 248 MGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQM 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:TIGR01972 328 ISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFLA 407

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 312839598  160 GTGTLITAAYSLYLFLKTQRGTLP-THIINLQPYHTREHLLMALHLLPVIML 210
Cdd:TIGR01972 408 ALGIVLAAAYMLTLYKRVFFGELSnPEVAEFPDLNGREIAVLAPLVVLILFL 459
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-174 3.61e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 127.09  E-value: 3.61e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFI-ILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:MTH00217 251 LGGYGFIRFSWPLLPEASEYFSPLIqTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAAIFLM 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:MTH00217 331 LAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIVGVLA 410

                        170
                 ....*....|....*
gi 312839598 160 GTGTLITAAYSLYLF 174
Cdd:MTH00217 411 SLGMVLSAGYSIYLY 425
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-211 5.03e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 126.72  E-value: 5.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFII-LALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:MTH00204 254 LGGYGFLRFSWPLFPAASEYFAPLIVmLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAAVFLM 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:MTH00204 334 LAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGLGVLV 413

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 312839598 160 GTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREhllmALHLLPVIMLI 211
Cdd:MTH00204 414 TSGMVWSAAYSLYLYNRISFGGGSNYLLFSRDLNRRE----LLAILPLIIAI 461
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-173 3.62e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 113.48  E-value: 3.62e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFII-LALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:MTH00226 275 LGGYGLVRLSWPILPLGAQNLAPAVIaMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSIFIM 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTIT 159
Cdd:MTH00226 355 LAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIGVFV 434

                        170
                 ....*....|....
gi 312839598 160 GTGTLITAAYSLYL 173
Cdd:MTH00226 435 CSGVILSAVYSFYF 448
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-154 1.33e-23

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 97.14  E-value: 1.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMMIMLDP--LSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:COG0651  251 GVYAILRVLTLLFGadPALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHL 330

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:COG0651  331 LNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAW 405
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-144 3.33e-23

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 96.64  E-value: 3.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRM-MIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:PRK12561 230 MGGYALIRFnVQMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGAMLQM 309

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLI 144
Cdd:PRK12561 310 ISHGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTV 374
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-144 1.21e-20

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 89.23  E-value: 1.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPF-IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:CHL00011 256 MGAYGLIRINMELLPHAHSIFSPWlVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQI 335

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312839598  80 IAHGLVSSALFCLANTTYERThsRTMVLAR--GMQLLLPLTATWWFIANLANLALPPLPNLMGELLI 144
Cdd:CHL00011 336 ISHGFIGAALFFLAGTSYDRI--RLVYLDEmgGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIV 400
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-148 1.10e-18

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 83.60  E-value: 1.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYP-FIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:PRK02546 258 MGGYALLRMNAGMLPDAHAQFAPlLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAMLQM 337

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAM 148
Cdd:PRK02546 338 ISHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFVGF 406
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 24-154 3.06e-17

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 79.59  E-value: 3.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  24 FIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSR 103
Cdd:PRK06458 284 LLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVLQKYGTR 363

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 312839598 104 TMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:PRK06458 364 DINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLARGPL 414
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-220 5.45e-17

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 78.97  E-value: 5.45e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFiiLALWGII--MTGSIC-LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAII 77
Cdd:PRK06473 250 LGTYGLLRFGVGLFPEAWVYLAPW--LATWAVVsvLYGASCaIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAAVF 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  78 LMIAHGLVSSALFCLANTTYERTHSRTMVLARGM---QLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:PRK06473 328 QMISHGLISALLFLLVGVVYKKTGSRDVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIFPV 407

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 312839598 155 TLTITGTGTLITAAYSLYLFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPELMWGW 220
Cdd:PRK06473 408 QTLLCMIGTGLTAVYFLLLVNRVFFGRLTAELSNLPRVLWSERLPALVLAVLIVVLGIQPSWLVRW 473
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-173 1.38e-15

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 74.56  E-value: 1.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMaypFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:MTH00094 196 LGTAGFLRILGSLNFVYNNF---WIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLMMML 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:MTH00094 273 AHGYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFFFIF 352

                        170
                 ....*....|...
gi 312839598 161 TGTLITAAYSLYL 173
Cdd:MTH00094 353 FYFLVSFYYSLFL 365
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-153 1.36e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 68.84  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMM-------IMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTG 74
Cdd:PRK12667 269 GAYAIIRFLytifgisPSLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAA 348

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312839598  75 AIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSP 153
Cdd:PRK12667 349 ALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGF 427
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-147 3.22e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 67.60  E-value: 3.22e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   4 YGMMRMMI----MLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:PRK08375 250 YALIRIYFtvfgGDFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHL 329

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITA 147
Cdd:PRK08375 330 LHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVG 397
PRK12650 PRK12650
DUF4040 family protein;
25-135 3.64e-11

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 61.98  E-value: 3.64e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRT 104
Cdd:PRK12650 276 IIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRD 355

                         90       100       110
                 ....*....|....*....|....*....|.
gi 312839598 105 MVLARGMQLLLPLTATWWFIANLANLALPPL 135
Cdd:PRK12650 356 IRRLGSLWRRMPFTFVSVTIAALSMAAVPPL 386
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 4-149 4.54e-11

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 61.67  E-value: 4.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   4 YGMMRmmIMLDPLSKEMAYPFIIL------ALWGIIMTgsicLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTG--- 74
Cdd:PRK08667 253 YGLVR--FLMDVLSPELWWGVLILlagsisALLGVIYA----LKEHDLKGLLAYSSIENIGIILMGIGLYVIFGVYGldt 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  75 --------AIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIIT 146
Cdd:PRK08667 327 lallalggALFHSLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELLLYE 406


                 ...
gi 312839598 147 AMF 149
Cdd:PRK08667 407 SFF 409
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-177 3.15e-10

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 59.00  E-value: 3.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALwGIIMTGSIC---LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAII 77
Cdd:PRK08676 251 IGIYGILRLSALLRQSGAAEQFSNVLIGL-GIFSIAVAAfsmLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLF 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  78 LMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLT 157
Cdd:PRK08676 330 HMLAHSLVKSGLFFSAGILHRQYRSDRFDRIFDVFRLQPVAAWGVILGSAAIIGMPPFPLFLSKFFILLQLGGISVWLVL 409

                        170       180
                 ....*....|....*....|
gi 312839598 158 ITGTGTLITAAYSLYLFLKT 177
Cdd:PRK08676 410 AVLLLLLLAASSFAIFLLKA 429
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 25-150 8.10e-10

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 57.85  E-value: 8.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRT 104
Cdd:PRK08377 277 IIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGTE 356

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 312839598 105 MVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFN 150
Cdd:PRK08377 357 IEKFEGLGKRMPLTALALTIGALSTVGIPLFNVFWSKFRIILAGLS 402
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 24-154 1.01e-09

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 57.62  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  24 FIILALWG---IIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERT 100
Cdd:PRK12647 259 QTILPLFGgltMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHET 338

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 312839598 101 HSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:PRK12647 339 GTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALLEAPLW 392
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
1-185 6.56e-09

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 55.10  E-value: 6.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPfiILALWGII--MTGS-ICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAII 77
Cdd:PRK07363 250 LGTYGLLRFGLQLFPQTWSLVAP--GLAIIGTIsvIYGAlSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLGAVA 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  78 LMIAHGLVSSALFCLANTTYERTHSRTM-VLARGMQLL--LPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPW 154
Cdd:PRK07363 328 QMISHGLILALLFHLVGIVERKVGTRDLdVLNGLMNPIrgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFSTFPI 407

                        170       180       190
                 ....*....|....*....|....*....|.
gi 312839598 155 TLTITGTGTLITAAYSLYLFLKTQRGTLPTH 185
Cdd:PRK07363 408 PTLLCIVASGLTAVYFVILLNRTCFGRLDNK 438
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 25-186 1.03e-08

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 54.39  E-value: 1.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQtpwGFTGAIILMIAHGLVSSALFCLANTTYERTHSRT 104
Cdd:COG1009  279 AIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRD 355

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598 105 MVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMF---NWSPWTLTITGTGTLITAAYSLYLFLKT---- 177
Cdd:COG1009  356 IRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALeagGLGPLLLAVALLGAFLTAFYSFRLFFLVffgk 435


                 ....*....
gi 312839598 178 QRGTLPTHI 186
Cdd:COG1009  436 PRPKTPKHP 444
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 22-135 1.91e-08

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 53.85  E-value: 1.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  22 YPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTH 101
Cdd:PRK08668 273 YILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTG 352

                         90       100       110
                 ....*....|....*....|....*....|....
gi 312839598 102 SRTMVLARGMQLLLPLTATWWFIANLANLALPPL 135
Cdd:PRK08668 353 TTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPM 386
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
25-150 8.60e-08

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 51.57  E-value: 8.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRT 104
Cdd:PRK06277 270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 312839598 105 MVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFN 150
Cdd:PRK06277 350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQ 395
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 25-150 8.70e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 51.74  E-value: 8.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRT 104
Cdd:PRK06589 284 IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQ 363

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 312839598 105 MVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFN 150
Cdd:PRK06589 364 VDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASE 409
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
2-215 8.82e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 51.87  E-value: 8.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSI-CLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMI 80
Cdd:PRK12663 252 GIYALIRVFTLLFPQERELLHPLLATMAAITMVIGALgALAYKDIRRIAGYQVISSIGFILLGLALGTPAGINGAIFYLV 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  81 AHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFNWSPWTLTITG 160
Cdd:PRK12663 332 HDMVVKTALFLIAGSLVRLTGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALM 411

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 312839598 161 TGTLITAAYSLY-LFLKTQRGTLPTHIINLQPYHTREHLLMALHLLPVIMLITKPE 215
Cdd:PRK12663 412 LITSLITMYSLFrIFFLAYWGDKDGEEVNFKPIPLYRKLPLSILAVVVIAMGIAAE 467
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 1-149 9.56e-08

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 51.51  E-value: 9.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQ---TPWGFTGAII 77
Cdd:PRK06525 252 VGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQLGYMFFGLSLAilgSRLALEGSIA 331

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 312839598  78 LMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMF 149
Cdd:PRK06525 332 YIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVPPFNGFFSKFPIFAAGF 403
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-149 3.65e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 49.95  E-value: 3.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMMIMLDPLSKEMAYPFI-ILALWGIIMtGSI-CLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILM 79
Cdd:PRK07691 255 GVYAIARTFTLFFSHDTSFTHYLIlILALLTIIF-GVIgAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAIYYL 333

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  80 IAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMF 149
Cdd:PRK07691 334 IHDMIVKAALFLLIGIMIKITGTTDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTF 403
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 6-90 1.56e-06

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 47.80  E-value: 1.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   6 MMRMMIM-LDPLSKEMAYPFIILALwgIIMT-GSIC-LRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAH 82
Cdd:COG1007  253 LLRLLVEaFPGLAADWQLLLAVLAV--LSMTvGNLAaLAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAY 330


                 ....*...
gi 312839598  83 GLVSSALF 90
Cdd:COG1007  331 LFMNLGAF 338
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 42-147 1.74e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 48.04  E-value: 1.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  42 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATW 121
Cdd:PRK12665 294 QSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIYYVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVL 373

                         90       100
                 ....*....|....*....|....*..
gi 312839598 122 WFIANLaNLA-LPPLPNLMGELLIITA 147
Cdd:PRK12665 374 FFVPAL-NLGgIPPFSGFIGKVALLEA 399
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 24-134 2.55e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 47.42  E-value: 2.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  24 FIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSR 103
Cdd:PRK12662 282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSISYHFGTT 361

                         90       100       110
                 ....*....|....*....|....*....|.
gi 312839598 104 TMVLARGMQLLLPLTATWWFIANLANLALPP 134
Cdd:PRK12662 362 KLEDCLNLWKSMPKITLAFVLLSLSLIGMPP 392
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-150 2.98e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 47.01  E-value: 2.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMMIMLDPLSKEMA---YPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMG---------LVAGGILIQTP 69
Cdd:PRK08376 265 GLYALARVLFSIYGPAINLAtvgWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGymllglgvgLAALGDPAMAS 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  70 WGFT---GAIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLII- 145
Cdd:PRK08376 345 YGEIalaGGIYHIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYe 424


                 ....*.
gi 312839598 146 -TAMFN 150
Cdd:PRK08376 425 sSALFN 430
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-102 5.10e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.48  E-value: 5.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   2 GGYGMMRMMIMLDPLSKEMAYPFIILALWGIImtgsICLRQTDLKSLIAYSSVSHMGLVAGGILIqtpwgftgAIILMIA 81
Cdd:PRK07234 230 GVFPLVRCALDVPGLDLIVRIFGVGTALLGVL----FALLEKDLKRMLAFSTISQLGFILAAPLV--------GGLYALA 297

                         90       100
                 ....*....|....*....|.
gi 312839598  82 HGLVSSALFCLANTTYERTHS 102
Cdd:PRK07234 298 HGLVKSTLFLCAGALPSRNFT 318
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
6-90 1.59e-05

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 44.81  E-value: 1.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   6 MMRMMIM-LDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGL 84
Cdd:PRK05777 254 LLRLLVVaFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLF 333


                 ....*.
gi 312839598  85 VSSALF 90
Cdd:PRK05777 334 MTLGAF 339
PRK12648 PRK12648
putative monovalent cation/H+ antiporter subunit A; Reviewed
 42-135 5.11e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237157 [Multi-domain]  Cd Length: 948  Bit Score: 43.64  E-value: 5.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  42 QTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATW 121
Cdd:PRK12648 292 QHDLKGLLAYSTISHLGLITLLLGLGSPLAAVAAIFHIINHATFKASLFMAAGIIDHETGTRDMRRLSGLRRLMPITATL 371

                         90
                 ....*....|....
gi 312839598 122 WFIANLANLALPPL 135
Cdd:PRK12648 372 AMVAAAAMAGVPLL 385
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 40-149 5.86e-05

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 43.34  E-value: 5.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  40 LRQTDLKSLIAYSSVSHMGLV-----------AGGILIQTPWGFTGAIILMIAHGLVSSALFCLANTTYERTHSRTMVLA 108
Cdd:PRK06521 295 LAEHDLKRLLAYSTIENIGIIfvglglamvfiAYGMPLLAALALTAALYHLLNHALFKSLLFLGAGAVLHATGTRDMEKL 374

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 312839598 109 RGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMF 149
Cdd:PRK06521 375 GGLIRRMPWTAWAFLIGCLAISALPPLNGFVSEWLLLQSLL 415
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 25-90 9.23e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 39.91  E-value: 9.23e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 312839598  25 IILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALF 90
Cdd:PRK12644 271 LVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALF 336
PRK08042 PRK08042
formate hydrogenlyase subunit 3; Reviewed
 1-150 1.33e-03

formate hydrogenlyase subunit 3; Reviewed


Pssm-ID: 181206 [Multi-domain]  Cd Length: 593  Bit Score: 39.43  E-value: 1.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   1 LGGYGMMRMMIMLDPLSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLV-----AG--GILIQTP---- 69
Cdd:PRK08042 225 IGLLGILTLSLLGGNAPLWWGVALLVLGMITAFVGGLYALMEHNIQRLLAYHTLENIGIIllglgAGvtGIALEQPalia 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  70 WGFTGAIILMIAHGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMF 149
Cdd:PRK08042 305 LGLVGGLYHLLNHSLFKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEWVIYQSFF 384


                 .
gi 312839598 150 N 150
Cdd:PRK08042 385 K 385
PRK12646 PRK12646
DUF4040 family protein;
16-150 1.38e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 39.35  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598  16 LSKEMAYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVA-----GGILIQTPWG---------FTGAIILMIA 81
Cdd:PRK12646 269 LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMamvgiGGGYAQHQQDaiasiyvfvLFAALFHLMN 348

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312839598  82 HGLVSSALFCLANTTYERTHSRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFN 150
Cdd:PRK12646 349 HAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQ 417
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 24-150 2.17e-03

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 38.39  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312839598   24 FIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAIILMIAHGLVSSALF-CLANT-TYERTH 101
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFgVLSLLrSYKDEW 351

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 312839598  102 SRTMVLARGMQLLLPLTATWWFIANLANLALPPLPNLMGELLIITAMFN 150
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLK 400
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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