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Conserved domains on  [gi|311088365|gb|ADP68415|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Lepilemur scottorum]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 2-347 9.50e-157

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.13  E-value: 9.50e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00105   2 NPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00105  82 GQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00105 162 ILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQITK 321
Cdd:MTH00105 242 SLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTK 321

                        330       340
                 ....*....|....*....|....*.
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTLSVLH 347
Cdd:MTH00105 322 PMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 2-347 9.50e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.13  E-value: 9.50e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00105   2 NPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00105  82 GQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00105 162 ILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQITK 321
Cdd:MTH00105 242 SLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTK 321

                        330       340
                 ....*....|....*....|....*.
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTLSVLH 347
Cdd:MTH00105 322 PMTLLPTLIILSTMLLPLTPMLSILE 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.17e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   23 SSHWLLMWIGLEINMLGIIP-ILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIID-----------SH 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDElskaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   91 NQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLL-TWQKLAPISIM-----LQIHLWTNLSTLLPIAISSILV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  165 GGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTT---------LTLTSLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhtrniRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 311088365  236 KTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 2.73e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.63  E-value: 2.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  18 MLTMISS-HWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIID-----SH 90
Cdd:COG1007  115 MMLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGiaaalAA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  91 NQLISLTTTIALTM-------KLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQI---------HLWTNLstL 154
Cdd:COG1007  195 GGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpglaADWQLL--L 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 155 LPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTfcpSLTVLN-------LLIYLTLTIVMFTTLNLNTSTTT 227
Cdd:COG1007  273 AVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLA---AGTPLGvsaalfyLLAYLFMNLGAFAVILLLSRKGG 349

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 311088365 228 LTLTS-----LWNKTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIY 298
Cdd:COG1007  350 EAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 3.59e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.08  E-value: 3.59e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365    4 TILSLIAITiftGTMLTMISSHWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSG 82
Cdd:TIGR01770 105 YILLLFALL---GIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   83 QWNIIDSHNQLISLTTTI------------ALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLW-- 148
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLNIsllllgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYil 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  149 -----TNLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMfTTLNLNT 223
Cdd:TIGR01770 262 fgfseAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  224 STTTLTLTSLWNKT-----------PMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYF 292
Cdd:TIGR01770 341 LSLLRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*
gi 311088365  293 YMRLI 297
Cdd:TIGR01770 421 YLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 2-347 9.50e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.13  E-value: 9.50e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00105   2 NPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00105  82 GQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00105 162 ILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQITK 321
Cdd:MTH00105 242 SLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTK 321

                        330       340
                 ....*....|....*....|....*.
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTLSVLH 347
Cdd:MTH00105 322 PMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 2-346 1.39e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 325.99  E-value: 1.39e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00135   2 NPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLwTNLSTLLPIAISS 161
Cdd:MTH00135  82 GQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAP-TNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQITK 321
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTLSVL 346
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 2-343 4.01e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 322.16  E-value: 4.01e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00112   2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00112  82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00112 162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQiTK 321
Cdd:MTH00112 242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK-PK 320

                        330       340
                 ....*....|....*....|..
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTL 343
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMI 342
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 2-343 9.99e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 321.10  E-value: 9.99e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00070   2 SPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00070  82 GEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00070 162 TLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQiTK 321
Cdd:MTH00070 242 SMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-NK 320

                        330       340
                 ....*....|....*....|..
gi 311088365 322 QTQLMPPLIILSTLSLPLSPTL 343
Cdd:MTH00070 321 TNNLLSLTIILSLMLLPITPTI 342
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 2-346 1.54e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 241.41  E-value: 1.54e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00200   2 SPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00200  82 GQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00200 162 VLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKWQLQITK 321
Cdd:MTH00200 242 MLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNS 321

                        330       340
                 ....*....|....*....|....*
gi 311088365 322 QTqLMPPLIILSTLSLPLSPTLSVL 346
Cdd:MTH00200 322 NL-LVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 2-307 3.16e-75

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 235.60  E-value: 3.16e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYS 81
Cdd:MTH00041   2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISS 161
Cdd:MTH00041  82 GSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTT 241
Cdd:MTH00041 162 VLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISA 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 311088365 242 LTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPT 307
Cdd:MTH00041 242 FLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 8-343 1.53e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 171.54  E-value: 1.53e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   8 LIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMysgqwnII 87
Cdd:MTH00160   9 LFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  88 DSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIhlwTNLSTLLPIAISSILVGGW 167
Cdd:MTH00160  83 MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIGAI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 168 GGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTTLTIMIT 247
Cdd:MTH00160 160 GGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLN 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 248 LLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNtslTLFPTFNNTKMKWQLQITKQTQLMP 327
Cdd:MTH00160 240 LLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS---SLMLNYNKNKWNLKKKKNKFSLILN 316

                        330
                 ....*....|....*.
gi 311088365 328 PLIILSTLSLPLSPTL 343
Cdd:MTH00160 317 FLSFISLFGLILSSLL 332
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-315 7.87e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 166.60  E-value: 7.87e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  13 IFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWniidshnq 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW-------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  93 LISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIH-LWTNLSTLLPIAISSILVGGWGGLN 171
Cdd:MTH00144  85 FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLdLYWLAYLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 172 QTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLwNKTPMTTLTIMITLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSL 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 311088365 252 GGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTSLTLFPTFNNTKMKW 315
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-312 7.14e-43

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 151.09  E-value: 7.14e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   6 LSLIAITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWN 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  86 IIdshnqlISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLLPIAISSILVG 165
Cdd:MTH00011  88 NI------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 166 GWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTTLTIM 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 311088365 246 ITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNtSLTLFPTFNNTK 312
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLK 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-300 7.82e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.18  E-value: 7.82e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  11 ITIFTGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVfnAMYSGQWNIIDSH 90
Cdd:MTH00197   5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLYLSLLSV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  91 nqlisLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHlwTNLSTLLPIAISSILVGGWGGL 170
Cdd:MTH00197  83 -----VLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNS--SSFMGLLICSVLSSLIGGIGGM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 171 NQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWNKTPMTTLTIMITLLS 250
Cdd:MTH00197 156 NQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 311088365 251 LGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNT 300
Cdd:MTH00197 236 LGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-298 5.50e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 96.24  E-value: 5.50e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   8 LIAITIFtGTMLTMISSHWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNI 86
Cdd:MTH00199 102 LILIVAL-GSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  87 IDSHNQLIS----LTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLstLLPIAISSI 162
Cdd:MTH00199 181 QGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNV--VLICAVLSI 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 163 LVGGWGGLNQTQLRKILAYSSITHMG---WMMAILTFCP-SLTVLNLLIYLTLTIVMFTTLNLNTSTTTLT--LTSLWNK 236
Cdd:MTH00199 259 IYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSIILSLKLTKGLIveVSGLSRK 338

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 311088365 237 TPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIY 298
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-297 8.26e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.93  E-value: 8.26e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  16 GTMLTMISSHWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIV-------------FNAMYS 81
Cdd:MTH00196   5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINLVLN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLwtNLSTLLPIAISS 161
Cdd:MTH00196  85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 162 ILVGGWGGLNQTQLRKILAYSSITHMG---WMMAILTFC---PSLTVLNLLIYLTLTIVMFTTLNLNTSTTTLTLTSLWN 235
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFEsiqASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 311088365 236 KTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLI 297
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 1.17e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   23 SSHWLLMWIGLEINMLGIIP-ILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIID-----------SH 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDElskaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   91 NQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLL-TWQKLAPISIM-----LQIHLWTNLSTLLPIAISSILV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  165 GGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMFTTLNLNTSTTT---------LTLTSLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhtrniRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 311088365  236 KTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 2.73e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.63  E-value: 2.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  18 MLTMISS-HWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIID-----SH 90
Cdd:COG1007  115 MMLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGiaaalAA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  91 NQLISLTTTIALTM-------KLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQI---------HLWTNLstL 154
Cdd:COG1007  195 GGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpglaADWQLL--L 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 155 LPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTfcpSLTVLN-------LLIYLTLTIVMFTTLNLNTSTTT 227
Cdd:COG1007  273 AVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLA---AGTPLGvsaalfyLLAYLFMNLGAFAVILLLSRKGG 349

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 311088365 228 LTLTS-----LWNKTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIY 298
Cdd:COG1007  350 EAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 4-297 3.59e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.08  E-value: 3.59e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365    4 TILSLIAITiftGTMLTMISSHWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSG 82
Cdd:TIGR01770 105 YILLLFALL---GIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   83 QWNIIDSHNQLISLTTTI------------ALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLW-- 148
Cdd:TIGR01770 182 SLNFEDLLLFLSNGMLNIsllllgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYil 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  149 -----TNLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVMfTTLNLNT 223
Cdd:TIGR01770 262 fgfseAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  224 STTTLTLTSLWNKT-----------PMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYF 292
Cdd:TIGR01770 341 LSLLRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*
gi 311088365  293 YMRLI 297
Cdd:TIGR01770 421 YLRVV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
5-215 3.72e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 82.18  E-value: 3.72e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   5 ILSLIAitifTGTMLTMISS-HWLLMWIGLEINMLGI-IPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSG 82
Cdd:PRK05777 107 LLVLFA----LLGMMVMVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATG 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  83 QWNIIDSHNQLISLTTT------------IALTMKLGMAPFHFWVPEVTQG--------------ISLMTGMLLLTWQKL 136
Cdd:PRK05777 183 SLSFAGIAKALADGSGNsllllfglvfllVGLAFKLSAVPFHMWTPDVYEGaptpvtaflatapkIAAFAVLLRLLVVAF 262

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 311088365 137 APISIMLQIHLWTnlstllpIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYLTLTIVM 215
Cdd:PRK05777 263 GGLSEDWQQVLAI-------IAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFM 334
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-301 2.45e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 70.56  E-value: 2.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  15 TGTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIIDSHNQLI 94
Cdd:COG0651  118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLA 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  95 SLTTTIALT----------MKLGMAPFHFWVPE-----------VTQGISLMTGM--LLLTWQKLAPISIMLQIHLWtnl 151
Cdd:COG0651  198 ELDPGLLLAafalllvgfgIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGTL--- 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 152 stLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYL----TLTIVMF----TTLNLNT 223
Cdd:COG0651  275 --LLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFlaagAIERATG 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311088365 224 STTTLTLTSLWNKTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIMALLNLYFYMRLIYNTS 301
Cdd:COG0651  353 TRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-191 3.16e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 67.58  E-value: 3.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  16 GTMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRST---------EAATKYFLVQTTASMLLMFAIVFNAMYSGQ--- 83
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  84 -----------WNIIDSHNQLISLTTTIALTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLs 152
Cdd:MTH00198 280 lgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL- 358

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 311088365 153 tLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:MTH00198 359 -LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 1.95e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 52.65  E-value: 1.95e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 311088365  291 YFYMRLIYNTSLTLFPTFNNTKMKWQLQITKQTQLMPPLIILSTLSLPLSP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-209 5.73e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 54.29  E-value: 5.73e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   9 IAITIFTGTMLTMISSHWLLMWIGLEinMLGIIPILMKNY---KPRSTEAATKYFLVQTTASMLLMFAI-VFNAMYSGQW 84
Cdd:PRK02504 115 ILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSsLLYGLSGGST 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  85 NIIDSHNQLI---SLTTTIALTM-------KLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHL------- 147
Cdd:PRK02504 193 QLSAIALALItspSLGLALALVFviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVtafpsfd 272

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 311088365 148 --WTNLSTLLpiAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCP----SLTVLNLLIYL 209
Cdd:PRK02504 273 eqWKLLFTAL--AILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTeagyASMVFYLLAYL 338
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 50-209 7.03e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 53.73  E-value: 7.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  50 PRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIIDSHNQLISLTTT--------IALTMKLGMAPFHFWVP----E 117
Cdd:PRK08375 152 RRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALAENPTVvtafgfvlLALALKAAVFPLHTWLPraypA 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 118 VTQGISLMTGMLLLTWQKLAPISIMLQI------HLWTNLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08375 232 APPVVTALLSGLVTKVAVYALIRIYFTVfggdfrFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYIL 311

                        170
                 ....*....|....*...
gi 311088365 192 AILTFCPSLTVLNLLIYL 209
Cdd:PRK08375 312 LGLALLTPLALAAGLLHL 329
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 1.03e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.16  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  55 AATKYFLVQTTASMLLMFAIVFNAMYSGQW--NIIDSHNQLISLTTT--------IALTMKLGMAPFHFWVPEV-----T 119
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTAQlllflaffIAFAVKVPMFPFHTWLPDAhveapT 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 120 QGISLMTGMLL----------------LTWQKLAPIsimlqihlwtnlstLLPIAISSILVGGWGGLNQTQLRKILAYSS 183
Cdd:COG1008  242 AGSVLLAGVLLkmggygllrfalplfpEASAYFAPL--------------LAALGVIGIIYGALVALAQTDLKRLIAYSS 307


                 ....*....
gi 311088365 184 ITHMGWMMA 192
Cdd:COG1008  308 VSHMGFVLL 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 49-196 1.16e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.94  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   49 KPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQ-WNIIDSHNQLISLTTT--------IALTMKLGMAPFHFWVPEV- 118
Cdd:TIGR01972 151 GPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGVQtwlflaffIAFAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  119 ----TQGISLMTGMLLltwqKLAPISIM-LQIHLWTNLST-----LLPIAISSILVGGWGGLNQTQLRKILAYSSITHMG 188
Cdd:TIGR01972 231 veapTAGSVILAGVLL----KMGTYGFLrFNLPLFPDASLyfapvLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMG 306


                  ....*....
gi 311088365  189 W-MMAILTF 196
Cdd:TIGR01972 307 FvLLGIFSF 315
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 11-191 3.65e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 48.55  E-value: 3.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  11 ITIFTGTMLTMISSHWLL-MWIGLEINML-GIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIvfnAMYSGQWNIID 88
Cdd:PRK08376 127 ILLLELGMLGMAITGDLFnFFVFLEIMSIaSYALVAFRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLN 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  89 ----SHNqlISLTTTI-----------ALTMKLGMAPFHFWVPEV-TQGISLMTGMLLLTWQ----KLAPISIML---QI 145
Cdd:PRK08376 204 maylAVK--MSENPTVvakialalfiaGLAMKSGAVPVHMWLPDAyPAAPSSISAMLLVIKQaglyALARVLFSIygpAI 281

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 311088365 146 HLWTNLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08376 282 NLATVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 11-194 6.05e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 47.84  E-value: 6.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  11 ITIFTGTMLTM-ISSHWLLMWIGLEinMLGIIPILM---KNYKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNI 86
Cdd:COG1009  117 LLLFMAAMLGLvLSDNLLLLFVFWE--LVGLCSYLLigfWYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNF 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  87 ID----SHNQLISLTTTIALTM-------KLGMAPFHFWVPE-----------------VTQGISLMTgmllltwqKLAP 138
Cdd:COG1009  195 SEllaaAPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDamegptpvsallhaatmVKAGVYLLA--------RLSP 266

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 311088365 139 IsiMLQIHLWtnLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAIL 194
Cdd:COG1009  267 L--FALSPVW--LTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 8.20e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.42  E-value: 8.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  55 AATKYFLVQTTASMLLMFAI----VFNAMYSGQWNIIDSHNQLISLTTT--------IALTMKLGMAPFHFWVPEV---- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNLPLPPGVQywlflaffIAFAVKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 119 -TQGISLMTGMLLltwqKLAP---ISIMLQI-----HLWTNLstLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGW 189
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAyglLRFSLPLfpdasHEFAPI--IITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                 ..
gi 311088365 190 MM 191
Cdd:PRK05846 316 VT 317
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 4.97e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.94  E-value: 4.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  55 AATKYFLVQTTASMLLMFAIVFNAMYSGQ--WNIIDSHNQLISLTTT--------IALTMKLGMAPFHFWVP----EVTQ 120
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAKSYPLALElllyagflIAFGVKLPIFPLHTWLPdahgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 311088365 121 GISLMTGMLLLTWQKLAPISIMLQI----HLwTNLSTLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALIRFNVQMlpdaHV-YFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVL 291
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-299 2.00e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 39.80  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365   2 NPTILSLIAITIFTGtMLTMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMF---AIVFNA 78
Cdd:PRK06589 115 SSRFLFFFNLTILIG-VLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLpavILIYTK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  79 MYSGQW---NIIDSHNQLISLTTTIALTMKLGMAPFHFWVPE-----------------VTQGISLMTGMLLLTWqKLAP 138
Cdd:PRK06589 194 TGNLDFvsgGLFSKNQSIILLLMFIYGIAKTAIFPVHSWLPAamvahypvsallhavivVKTGLFCIYKILLYIF-GLSY 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 139 ISIMLQIHLWtnlstLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMMAILTFCPSLTVLNLLIYL--------T 210
Cdd:PRK06589 273 LQRIFAEFNW-----LIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLvshsfakiC 347

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 211 LTIVMFTTLNLNTSTTTLTLTSLWNKTPMTTLTIMITLLSLGGLPPLTGFLPKWAIIQELSKNNNITTATIMAIM----A 286
Cdd:PRK06589 348 LFYSMGSIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasS 427

                        330
                 ....*....|...
gi 311088365 287 LLNLYFYMRLIYN 299
Cdd:PRK06589 428 ILSALYLLKILSS 440
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 48-193 2.31e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 39.57  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  48 YKPRSTEAATKYFLVQTTASMLLMFAIVFNAMYSGQWNIID----SHNQLISLTT-----------------TIALTMKL 106
Cdd:PRK12667 158 DRGDAVEAAIKYALIGAVGTTLYFLALAFLYATFGTLNMADlsakIRGLSFPLTGglagnpplalgvalalaLWAFTIKA 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 107 GMAPFHFWVPEV----TQGISLMTGMLLLTWQKLAPISIMLQI-----HLWTNLSTLLPIAI----SSILVGGWGGLNQT 173
Cdd:PRK12667 238 AIFPNHFWLPDAhpaaPSPVSAMLSGLVVNVGAYAIIRFLYTIfgispSLIDFRAALSPILIilgaVSAIIGALMMVVQK 317

                        170       180
                 ....*....|....*....|.
gi 311088365 174 QLRKILAYSSITHMGW-MMAI 193
Cdd:PRK12667 318 DVKRLLAYSTISHMGYiFMGI 338
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-191 2.60e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.68  E-value: 2.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365 100 IALTMKLGMAPFHFWVP----EVTQGIS-LMTGMLL-LTWQKLAPISIMLQIHLWTNLS-TLLPIAISSILVGGWGGLNQ 172
Cdd:PRK06473 213 VGFGIKIPLVPFHTWLPdahvEASTPVSvLLAGVLLkLGTYGLLRFGVGLFPEAWVYLApWLATWAVVSVLYGASCAIAQ 292

                         90
                 ....*....|....*....
gi 311088365 173 TQLRKILAYSSITHMGWMM 191
Cdd:PRK06473 293 KDMKKMVAYSSIGHMGYIL 311
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-191 6.06e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.20  E-value: 6.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  17 TMLTMISSHWLLMWIGLEINMLgIIPILMKNYKPRST-EAATKYFLVQTTA------SMLLMFAIVFNAMYSG--QWNII 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTV-FSAMLIAILSARENiDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTEL 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  88 DSHNQLIS--------LTTTIALTMKLGMAPFHFWVPEV-TQGISLMTGMLLLTWQKLAPISIMLQIHLW-------TNL 151
Cdd:PRK08676 194 AAHASLLSpsvlgasfLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSALLrqsgaaeQFS 273

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 311088365 152 STLLPIAISSILVGGWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08676 274 NVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 13-190 7.42e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 37.99  E-value: 7.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  13 IFTGTML-TMISSHWLLMWIGLEINMLGIIPILMKNYKPRSTEAATKYFLVQTTASMLLMFAIVF----------NAMYS 81
Cdd:PRK06458 116 LFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTILvyanaatvmgDGEMA 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 311088365  82 GQWNIIDSHN-----QLISLTTTIALT---MKLGMAPFHFWVP----EVTQGISLMTGMLLLTWQKLAPIS---IMLQIH 146
Cdd:PRK06458 196 ILWTELLKHAslldpTLMKLAFVFLLIgfgTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRyyiLIDAAI 275

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 311088365 147 LWTNLSTLLPI-AISSILVGGWGGLNQTQLRKILAYSSITHMGWM 190
Cdd:PRK06458 276 GSDFPGRLLLIfGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 102-155 8.77e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.54  E-value: 8.77e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 311088365 102 LTMKLGMAPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMLQIHLWTNLSTLL 155
Cdd:MTH00091  67 LMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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