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Conserved domains on  [gi|310941169|dbj|BAJ24487|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Ramulus mikado]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 8.83e-19

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 73.65  E-value: 8.83e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  2 LIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 310941169 82 GFGNDYFFS 90
Cdd:MTH00162 81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 8.83e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 73.65  E-value: 8.83e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  2 LIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 310941169 82 GFGNDYFFS 90
Cdd:MTH00162 81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-96 1.51e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 37.16  E-value: 1.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169   3 IYFIMSLFMFICGLLAFSFNyNHFLITLLSLEYIVLS--LFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLI 80
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLLR-RNLLRVLLSLELMLNAvnLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 310941169  81 RGFGNDYFFSFNLLQC 96
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 8.83e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 73.65  E-value: 8.83e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  2 LIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 310941169 82 GFGNDYFFS 90
Cdd:MTH00162 81 SHGNDYFSS 89
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-96 4.72e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 59.09  E-value: 4.72e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLM--FILTFWVCEAALGLSLLVS 78
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 310941169 79 LIRGFGNDYFFSFNLLQC 96
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-96 7.10e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 53.70  E-value: 7.10e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLI 80
Cdd:MTH00149  2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                        90
                ....*....|....*.
gi 310941169 81 RGFGNDYFFSFNLLQC 96
Cdd:MTH00149 82 RLHGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 1-96 1.72e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 52.67  E-value: 1.72e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLI 80
Cdd:MTH00188  2 FFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLI 81

                        90
                ....*....|....*.
gi 310941169 81 RGFGNDYFFSFNLLQC 96
Cdd:MTH00188 82 RSHGSDYVSSLNLIKC 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 11-96 6.80e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 48.45  E-value: 6.80e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169 11 MFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMY--LFISLYDLFFLMFILTFWVCEAALGLSLLVSLIRGFGNDYF 88
Cdd:MTH00067 11 AFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWstQFESLSYFSLPMFMLTFSACEASTGLALMVATTRTHGTDHL 90


                ....*...
gi 310941169 89 FSFNLLQC 96
Cdd:MTH00067 91 KNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 12-96 2.65e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 46.88  E-value: 2.65e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169 12 FICGLLAFSFNYNHFLITLLSLEYIVLSLFwlvymyLFISLYDLFFL--------MFILTFWVCEAALGLSLLVSLIRGF 83
Cdd:MTH00126 12 FILGLMGLAFHRTHLLSALLCLEGMMLSLF------IALSLWALQLEstsfsaapMLLLAFSACEASAGLALLVATARTH 85

                        90
                ....*....|...
gi 310941169 84 GNDYFFSFNLLQC 96
Cdd:MTH00126 86 GTDRLQNLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-96 4.23e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 43.97  E-value: 4.23e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICgLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYL-FISLYDLFFLMFILTFWVCEAALGLSLLVSL 79
Cdd:MTH00013  2 MSPLFILSISPFIS-MFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLmFANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                        90
                ....*....|....*..
gi 310941169 80 IRGFGNDYFFSFNLLQC 96
Cdd:MTH00013 81 TRSYGNDMLKSLTSNKC 97
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-95 7.14e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 43.37  E-value: 7.14e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWL--VYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVS 78
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNisIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 310941169 79 LIRGFGNDYFFSFNLLQ 95
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 5-94 8.95e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 43.01  E-value: 8.95e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  5 FIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLV--YMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLIRG 82
Cdd:MTH00181  2 MFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLalFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRT 81

                        90
                ....*....|..
gi 310941169 83 FGNDYFFSFNLL 94
Cdd:MTH00181 82 HGSDHLLKFNLL 93
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-96 3.83e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 41.45  E-value: 3.83e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169  1 MLIYFIMSLFMFICGLLAFSFNYNHFLITLLSLEYIVLSLFWLVYMYLFISLYDLFFLM--FILTFWVCEAALGLSLLVS 78
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 310941169 79 LIRGFGNDYFFSFNLLQC 96
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-96 1.51e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 37.16  E-value: 1.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 310941169   3 IYFIMSLFMFICGLLAFSFNyNHFLITLLSLEYIVLS--LFWLVYMYLFISLYDLFFLMFILTFWVCEAALGLSLLVSLI 80
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLLR-RNLLRVLLSLELMLNAvnLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 310941169  81 RGFGNDYFFSFNLLQC 96
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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