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Conserved domains on  [gi|308219158|gb|ADO22437|]
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epididymis secretory sperm binding protein [Homo sapiens]

Protein Classification

galectin family protein( domain architecture ID 10049222)

galectin family protein may exclusively bind beta-galactosides such as lactose in a manner independent of metal ions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 117-244 7.00e-55

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


:

Pssm-ID: 238025  Cd Length: 127  Bit Score: 172.43  E-value: 7.00e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158 117 PYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGN-DVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESG 195
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308219158 196 KPFKIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRL-PLESIDYLSINGDVSLTS 125
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 9-113 3.52e-07

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.75  E-value: 3.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   9 DALSGSGNPNPQGWPGAWGNQP-AGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG 87
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASaAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                         90       100
                 ....*....|....*....|....*.
gi 308219158  88 AYPSSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQA 724
 
Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 117-244 7.00e-55

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 172.43  E-value: 7.00e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158 117 PYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGN-DVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESG 195
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308219158 196 KPFKIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRL-PLESIDYLSINGDVSLTS 125
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 123-244 5.43e-54

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 170.08  E-value: 5.43e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   123 PGGVVPRMLITILGTVKPNANRIALDFQRG--NDVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESGKPFKI 200
Cdd:smart00908   1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 308219158   201 QVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRL-PLESIDTLEISGDVQLTS 120
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 123-244 8.85e-49

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 156.65  E-value: 8.85e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  123 PGGVVPRMLITILGTVKPNANRIALDFQRG----NDVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESGKPF 198
Cdd:pfam00337   1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308219158  199 KIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:pfam00337  78 ELTILVGDDHFKIYVNGQHFTTFKHRL-PPEDIDALQVRGDVKLTS 122
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 9-113 3.52e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.75  E-value: 3.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   9 DALSGSGNPNPQGWPGAWGNQP-AGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG 87
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASaAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                         90       100
                 ....*....|....*....|....*.
gi 308219158  88 AYPSSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQA 724
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
2-127 2.60e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 41.66  E-value: 2.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   2 ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYP-GAPAPGVYP 80
Cdd:COG3469   91 STSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATgGTTTTSTTT 170

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 308219158  81 GPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVV 127
Cdd:COG3469  171 TTTSASTTPSATTTATATTASGATTPSATTTATTTGPPTPGLPKHVL 217
G_path_suppress pfam15991
G-protein pathway suppressor; This family of proteins inhibits G-protein- and ...
 42-122 5.75e-04

G-protein pathway suppressor; This family of proteins inhibits G-protein- and mitogen-activated protein kinase-mediated signal transduction.


Pssm-ID: 464961 [Multi-domain]  Cd Length: 272  Bit Score: 40.29  E-value: 5.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   42 PGAYPGQapPGAYPGQAPPGAYPGAPGAYPGAPA------PGVYPGPPSGPGAYPSSGQPSA--TGAYPATGPygaPAGP 113
Cdd:pfam15991 147 QQAYYKQ--PAFSPGYAEHGQQKHDDGRRGYDVArfgswnKSTAQYPPSGQLFYPTHQYLPPpqTQGQADARL---QTIY 221


                  ....*....
gi 308219158  114 LIVPYNLPL 122
Cdd:pfam15991 222 PQPGYALPL 230
 
Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 117-244 7.00e-55

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 172.43  E-value: 7.00e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158 117 PYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGN-DVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESG 195
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308219158 196 KPFKIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRL-PLESIDYLSINGDVSLTS 125
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 123-244 5.43e-54

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 170.08  E-value: 5.43e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   123 PGGVVPRMLITILGTVKPNANRIALDFQRG--NDVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESGKPFKI 200
Cdd:smart00908   1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 308219158   201 QVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRL-PLESIDTLEISGDVQLTS 120
GLECT smart00276
Galectin; Galectin - galactose-binding lectin
 118-248 7.29e-54

Galectin; Galectin - galactose-binding lectin


Pssm-ID: 214596  Cd Length: 128  Bit Score: 169.72  E-value: 7.29e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   118 YNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGN-DVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESGK 196
Cdd:smart00276   1 FTLPIPGGLKPGQTLTVRGIVLPDAKRFSINLLTGGdDIALHFNPRFNEN---KIVCNSKLNGSWGSEEREGGFPFQPGQ 77

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 308219158   197 PFKIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTSASYT 248
Cdd:smart00276  78 PFDLTIIVQPDHFQIFVNGVHITTFPHRL-PLESIDYLSINGDVQLTSVSFE 128
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 123-244 8.85e-49

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 156.65  E-value: 8.85e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  123 PGGVVPRMLITILGTVKPNANRIALDFQRG----NDVAFHFNPRFNENnrrVIVCNTKLDNNWGREERQSVFPFESGKPF 198
Cdd:pfam00337   1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308219158  199 KIQVLVEPDHFKVAVNDAHLLQYNHRVkKLNEISKLGISGDIDLTS 244
Cdd:pfam00337  78 ELTILVGDDHFKIYVNGQHFTTFKHRL-PPEDIDALQVRGDVKLTS 122
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 9-113 3.52e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.75  E-value: 3.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   9 DALSGSGNPNPQGWPGAWGNQP-AGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG 87
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASaAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                         90       100
                 ....*....|....*....|....*.
gi 308219158  88 AYPSSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQA 724
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 12-114 2.01e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.44  E-value: 2.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  12 SGSGNPNPQGWPGAWGNQPAGAGGYPGAsypgAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPS 91
Cdd:PRK07764 643 PAPGVAAPEHHPKHVAVPDASDGGDGWP----AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPA 718

                         90       100
                 ....*....|....*....|...
gi 308219158  92 SGQPSATGAYPATGPYGAPAGPL 114
Cdd:PRK07764 719 AQPPQAAQGASAPSPAADDPVPL 741
PHA03378 PHA03378
EBNA-3B; Provisional
 16-129 2.22e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 45.44  E-value: 2.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  16 NPNPQGWPGAWGNQPAGAGGYPGASYPG-AYPGQAPPG-AYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSG 93
Cdd:PHA03378 675 QPSPTGANTMLPIQWAPGTMQPPPRAPTpMRPPAAPPGrAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRA 754

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 308219158  94 QPSATGAYPATGPYGAPAGPLIVPynlPLPGGVVPR 129
Cdd:PHA03378 755 RPPAAAPGRARPPAAAPGAPTPQP---PPQAPPAPQ 787
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 27-113 3.52e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 3.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  27 GNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPG--APGAYPGAPAPGVYPGPPSGPGAYPSSGQPS-ATGAYPA 103
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAApaPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSpPPAAAPS 463

                         90
                 ....*....|
gi 308219158 104 TGPYGAPAGP 113
Cdd:PRK07764 464 AQPAPAPAAA 473
PHA03378 PHA03378
EBNA-3B; Provisional
 17-139 3.88e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 44.67  E-value: 3.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  17 PNPQGWPGAwGNQPAGAGGypGASYPGAYPGQA-PPGAYPGQAPPGAypGAPGAypgAPAPGVYPGPPSGPGAYPSSG-- 93
Cdd:PHA03378 705 RPPAAPPGR-AQRPAAATG--RARPPAAAPGRArPPAAAPGRARPPA--AAPGR---ARPPAAAPGRARPPAAAPGAPtp 776

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 308219158  94 -QPSATGAYPATGPYGAPAgPLIVPYNLPLPGGVVPRMLITILGTVK 139
Cdd:PHA03378 777 qPPPQAPPAPQQRPRGAPT-PQPPPQAGPTSMQLMPRAAPGQQGPTK 822
PHA03247 PHA03247
large tegument protein UL36; Provisional
 15-128 5.51e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 5.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   15 GNPNPQGWPGAWGNQPAGAggyPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQ 94
Cdd:PHA03247 2752 GGPARPARPPTTAGPPAPA---PPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL 2828

                          90       100       110
                  ....*....|....*....|....*....|....
gi 308219158   95 PSATGAYPATGPygAPAGPliVPYNLPLPGGVVP 128
Cdd:PHA03247 2829 PPPTSAQPTAPP--PPPGP--PPPSLPLGGSVAP 2858
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 13-113 5.53e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 5.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  13 GSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPG--QAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYP 90
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                         90       100
                 ....*....|....*....|...
gi 308219158  91 SSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAP 693
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 23-113 7.49e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 43.52  E-value: 7.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  23 PGAWGNQPAGAGGYPGASYPGAypGQAPPgayPGQAPPGAYPGAPG-----AYPGAPAPGVYPGP--------------- 82
Cdd:PRK14959 373 PSGGGASAPSGSAAEGPASGGA--ATIPT---PGTQGPQGTAPAAGmtpssAAPATPAPSAAPSPrvpwddappapprsg 447

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 308219158  83 ------PSGPGAYPSSGQPSATGAYPATGP-YGAPAGP 113
Cdd:PRK14959 448 ipprpaPRMPEASPVPGAPDSVASASDAPPtLGDPSDT 485
PHA03378 PHA03378
EBNA-3B; Provisional
 17-150 1.30e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 42.75  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  17 PNPQGWPGAwGNQPAGAGGypGASYPGAYPGQA-PPGAYPGQAPPGAypGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQP 95
Cdd:PHA03378 725 RPPAAAPGR-ARPPAAAPG--RARPPAAAPGRArPPAAAPGRARPPA--AAPGAPTPQPPPQAPPAPQQRPRGAPTPQPP 799

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 308219158  96 satgaypatgPYGAPAGPLIVPYNLPLPGGVVPRMLITILgTVKPNANRIALDFQ 150
Cdd:PHA03378 800 ----------PQAGPTSMQLMPRAAPGQQGPTKQILRQLL-TGGVKRGRPSLKKP 843
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 37-111 2.11e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.01  E-value: 2.11e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 308219158  37 PGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVyPGPPSGPGAYPSSGQPSATGAYPATGPYGAPA 111
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAP-AAAASAPAAPPAAAPPAPVAAPAAAAPAAAPA 439
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-128 2.30e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 2.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   17 PNPQGWPGAWGNQPAGAGGypGASYPGAYPGQAPPGAYPGQAPPG--AYPGAPGAYPGAPAPGVYPGPPSGPGayPSSGQ 94
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAA--RQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAPPAAPAAGPP--RRLTR 2785

                          90       100       110
                  ....*....|....*....|....*....|....
gi 308219158   95 PSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVP 128
Cdd:PHA03247 2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAALP 2819
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 4-139 2.42e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 2.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   4 NFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPP 83
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ 465

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 308219158  84 SGPGAYPS-----SGQPSATGAYPATGPYGAPAGPliVPYNLPLPGGVVPRMLITILGTVK 139
Cdd:PRK07764 466 PAPAPAAApeptaAPAPAPPAAPAPAAAPAAPAAP--AAPAGADDAATLRERWPEILAAVP 524
PHA03247 PHA03247
large tegument protein UL36; Provisional
 42-125 2.51e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 2.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   42 PGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSG---PGAYPSSGQPSATGAYPATGPYGAPAGPliVPY 118
Cdd:PHA03247 2704 PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatPGGPARPARPPTTAGPPAPAPPAAPAAG--PPR 2781


                  ....*..
gi 308219158  119 NLPLPGG 125
Cdd:PHA03247 2782 RLTRPAV 2788
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
2-127 2.60e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 41.66  E-value: 2.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   2 ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYP-GAPAPGVYP 80
Cdd:COG3469   91 STSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATgGTTTTSTTT 170

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 308219158  81 GPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVV 127
Cdd:COG3469  171 TTTSASTTPSATTTATATTASGATTPSATTTATTTGPPTPGLPKHVL 217
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 10-113 2.88e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 2.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  10 ALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAyPGQAPPGayPGQAPPGAYPGA--------PGAYPGAPAPGVYPG 81
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP-AATPPAG--QADDPAAQPPQAaqgasapsPAADDPVPLPPEPDD 747

                         90       100       110
                 ....*....|....*....|....*....|..
gi 308219158  82 PPSGPGAYPSSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
dnaA PRK14086
chromosomal replication initiator protein DnaA;
9-113 3.35e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 41.35  E-value: 3.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   9 DALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPgAPAPGVYPGPPSgpgA 88
Cdd:PRK14086  89 DPSAGEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQ-RPEPGAWPRAAD---D 164

                         90       100
                 ....*....|....*....|....*
gi 308219158  89 YPSSGQPSatgAYPATGPYGAPAGP 113
Cdd:PRK14086 165 YGWQQQRL---GFPPRAPYASPASY 186
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
13-123 4.56e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  13 GSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPG-APGAYPGAPAPGVYPGPPSGPGAYPS 91
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAaAPARRSPAPEALAAARQASARGPGGA 447

                         90       100       110
                 ....*....|....*....|....*....|..
gi 308219158  92 SGQPSATGAYPATGPYGAPAGPLIVPYNLPLP 123
Cdd:PRK12323 448 PAPAPAPAAAPAAAARPAAAGPRPVAAAAAAA 479
G_path_suppress pfam15991
G-protein pathway suppressor; This family of proteins inhibits G-protein- and ...
 42-122 5.75e-04

G-protein pathway suppressor; This family of proteins inhibits G-protein- and mitogen-activated protein kinase-mediated signal transduction.


Pssm-ID: 464961 [Multi-domain]  Cd Length: 272  Bit Score: 40.29  E-value: 5.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   42 PGAYPGQapPGAYPGQAPPGAYPGAPGAYPGAPA------PGVYPGPPSGPGAYPSSGQPSA--TGAYPATGPygaPAGP 113
Cdd:pfam15991 147 QQAYYKQ--PAFSPGYAEHGQQKHDDGRRGYDVArfgswnKSTAQYPPSGQLFYPTHQYLPPpqTQGQADARL---QTIY 221


                  ....*....
gi 308219158  114 LIVPYNLPL 122
Cdd:pfam15991 222 PQPGYALPL 230
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
12-123 5.91e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 5.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  12 SGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAP----PGAYPGAPGAYPGAPAPGVYPGPPSGPG 87
Cdd:PRK12323 376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAParrsPAPEALAAARQASARGPGGAPAPAPAPA 455

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 308219158  88 AYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLP 123
Cdd:PRK12323 456 AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
PHA03247 PHA03247
large tegument protein UL36; Provisional
 37-129 5.93e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 5.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   37 PGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATgayPATGPYGAPAGPLIV 116
Cdd:PHA03247 2575 PRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN---EPDPHPPPTVPPPER 2651

                          90
                  ....*....|...
gi 308219158  117 PYNLPLPGGVVPR 129
Cdd:PHA03247 2652 PRDDPAPGRVSRP 2664
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
10-113 6.56e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 6.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  10 ALSGSGNPnpqgwPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAY 89
Cdd:PRK07003 361 AVTGGGAP-----GGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435

                         90       100
                 ....*....|....*....|....
gi 308219158  90 PSSGQPSATGAYPATGPYGAPAGP 113
Cdd:PRK07003 436 ADRGDDAADGDAPVPAKANARASA 459
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 10-113 6.73e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 40.43  E-value: 6.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  10 ALSGSGNPNPQGW-------PGAWGNQPA--GAGGYPGASYPGA-YPGQAPPGAYP-GQAPPGAYPGAPGAYPGAPAPGV 78
Cdd:PRK14959 380 APSGSAAEGPASGgaatiptPGTQGPQGTapAAGMTPSSAAPATpAPSAAPSPRVPwDDAPPAPPRSGIPPRPAPRMPEA 459

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 308219158  79 YPGPPSGPGAYPSSGQPSATGAYPATGPYgAPAGP 113
Cdd:PRK14959 460 SPVPGAPDSVASASDAPPTLGDPSDTAEH-TPSGP 493
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 17-113 8.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 8.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  17 PNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPG--AYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQ 94
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAapAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669

                         90
                 ....*....|....*....
gi 308219158  95 PSATGAYPATGPYGAPAGP 113
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPA 688
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
29-129 1.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 1.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  29 QPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYG 108
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARG 443

                         90       100
                 ....*....|....*....|.
gi 308219158 109 APAGPLIVPYNLPLPGGVVPR 129
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARP 464
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 19-113 1.20e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  19 PQGWPGAWGnQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVyPGPPSGPGAYPSSGQPSAT 98
Cdd:PRK07764 666 GDGWPAKAG-GAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQA-AQGASAPSPAADDPVPLPP 743

                         90
                 ....*....|....*
gi 308219158  99 GAYPATGPYGAPAGP 113
Cdd:PRK07764 744 EPDDPPDPAGAPAQP 758
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 16-131 2.40e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 38.93  E-value: 2.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  16 NPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGP-------GA 88
Cdd:PRK14951 382 ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPaqaapetVA 461

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 308219158  89 YPSSGQPSATGAYPATGPYGAPAGPLIVPYNL-PLPGGVVPRML 131
Cdd:PRK14951 462 IPVRVAPEPAVASAAPAPAAAPAAARLTPTEEgDVWHATVQQLA 505
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 37-117 2.64e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 38.72  E-value: 2.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   37 PGASYPGAYPGQAPPGAYPGQAP-PGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLI 115
Cdd:PRK12270   38 PGSTAAPTAAAAAAAAAASAPAAaPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117


                  ..
gi 308219158  116 VP 117
Cdd:PRK12270  118 TP 119
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-140 3.31e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   17 PNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPgqAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPS 96
Cdd:PHA03247 2723 PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPP--TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 308219158   97 ----------ATGAYPATGPYGAPAGPL-----IVPYNLPLPGGVVPRMLiTILGTVKP 140
Cdd:PHA03247 2801 pwdpadppaaVLAPAAALPPAASPAGPLppptsAQPTAPPPPPGPPPPSL-PLGGSVAP 2858
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 31-128 3.41e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.43  E-value: 3.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  31 AGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGayPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAP 110
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAA--PAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDAS 663

                         90
                 ....*....|....*...
gi 308219158 111 AGPLIVPYNLPLPGGVVP 128
Cdd:PRK07764 664 DGGDGWPAKAGGAAPAAP 681
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
29-111 3.72e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 38.29  E-value: 3.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  29 QPA-GAGGYPGASYPGAYPGQAP-PGAYPGQAPPGAYPGAPGAYPGAPA-----PGVYPGPPSGPGAYPSSGQPSATGA- 100
Cdd:PRK07003 359 EPAvTGGGAPGGGVPARVAGAVPaPGARAAAAVGASAVPAVTAVTGAAGaalapKAAAAAAATRAEAPPAAPAPPATADr 438

                         90
                 ....*....|...
gi 308219158 101 --YPATGPYGAPA 111
Cdd:PRK07003 439 gdDAADGDAPVPA 451
PHA03185 PHA03185
UL14 tegument protein; Provisional
 75-113 5.16e-03

UL14 tegument protein; Provisional


Pssm-ID: 177553 [Multi-domain]  Cd Length: 214  Bit Score: 37.31  E-value: 5.16e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 308219158  75 APGVYPGPPSGPGAYPSS-----GQPSATGAYPATGPYGAPAGP 113
Cdd:PHA03185 157 APAVRPGDLSGPGSRPTSgpvagGLPGGGAPAPPTPPRPGPTDP 200
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 12-114 5.38e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 37.66  E-value: 5.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  12 SGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGA----YPGAPGAYPGAPAPGVYPGPPSGPG 87
Cdd:PRK07764 692 APAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPpepdDPPDPAGAPAQPPPPPAPAPAAAPA 771

                         90       100
                 ....*....|....*....|....*..
gi 308219158  88 AYPSSGQPSATGAYPATGPYGAPAGPL 114
Cdd:PRK07764 772 AAPPPSPPSEEEEMAEDDAPSMDDEDR 798
MISS pfam15822
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ...
 13-117 5.73e-03

MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.


Pssm-ID: 318115 [Multi-domain]  Cd Length: 238  Bit Score: 37.27  E-value: 5.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   13 GSGNPNPQGWPGAWGNQPAGAGGYP-GASYPGAYPGQAPPGAYPGQAPpgayPGAPGAYPGAPAPGVYPGPPSGPGAYps 91
Cdd:pfam15822 128 APTDPAAAAPSGPWGSMSSGPWAPGmGGQYPAPNMPYPSPGPYPAVPP----PQSPGAAPPVPWGTVPPGPWGPPAPY-- 201

                          90       100
                  ....*....|....*....|....*.
gi 308219158   92 sgqPSATGAYPATGPYGAPAGPLIVP 117
Cdd:pfam15822 202 ---PDPTGSYPMPGLYPTPNNPFQVP 224
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
30-113 6.74e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 37.55  E-value: 6.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  30 PAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPgAPGAYPGAPAPgvyPGPPSGPGAYPSSGQPSATGAYPATGPYGA 109
Cdd:PRK12323 473 AAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA-SPAPAQPDAAP---AGWVAESIPDPATADPDDAFETLAPAPAAA 548


                 ....
gi 308219158 110 PAGP 113
Cdd:PRK12323 549 PAPR 552
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 19-111 6.85e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 37.56  E-value: 6.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158   19 PQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPgvyPGPPSGPGAYPSSGQPSAT 98
Cdd:PRK12270   39 GSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAP---AAPPAAAAAAAPAAAAVED 115

                          90
                  ....*....|...
gi 308219158   99 GAYPATGPYGAPA 111
Cdd:PRK12270  116 EVTPLRGAAAAVA 128
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
19-129 7.78e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 37.16  E-value: 7.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308219158  19 PQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAypgAPGAYPGAPAPGVYPGPPS-GPGAYPSSGQPSA 97
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAA---APAAAAAARAVAAAPARRSpAPEALAAARQASA 441

                         90       100       110
                 ....*....|....*....|....*....|..
gi 308219158  98 TGAYPATGPYGAPAgPLIVPYNLPLPGGVVPR 129
Cdd:PRK12323 442 RGPGGAPAPAPAPA-AAPAAAARPAAAGPRPV 472
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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