NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|302687492|ref|XP_003033426|]
View 

uncharacterized protein SCHCODRAFT_02619497 [Schizophyllum commune H4-8]

Protein Classification

cysteine-rich PDZ-binding protein( domain architecture ID 10562978)

cysteine-rich PDZ-binding protein (CRIPT) involved in the cytoskeletal anchoring of DLG4 in excitatory synapses

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 11-97 5.76e-26

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


:

Pssm-ID: 431159  Cd Length: 87  Bit Score: 92.06  E-value: 5.76e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302687492  11 SQLAAPDPFKSSSSS--IKDGSRKVGENKLLSRPGssKNRFQPYQGKCKDCKSSVSQNKAKYCHGCAYKKGICAICGKQI 88
Cdd:pfam10235  1 TKLATPDPWKDGARNtlGESGGRKINENKLLSKKA--KNPYAAYSSKCKICKTKVHQPGAKYCQGCAYKKGICAMCGKKL 78


                 ....*....
gi 302687492  89 LDTTGYVMS 97
Cdd:pfam10235 79 LDTKNYKQS 87
 
Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 11-97 5.76e-26

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


Pssm-ID: 431159  Cd Length: 87  Bit Score: 92.06  E-value: 5.76e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302687492  11 SQLAAPDPFKSSSSS--IKDGSRKVGENKLLSRPGssKNRFQPYQGKCKDCKSSVSQNKAKYCHGCAYKKGICAICGKQI 88
Cdd:pfam10235  1 TKLATPDPWKDGARNtlGESGGRKINENKLLSKKA--KNPYAAYSSKCKICKTKVHQPGAKYCQGCAYKKGICAMCGKKL 78


                 ....*....
gi 302687492  89 LDTTGYVMS 97
Cdd:pfam10235 79 LDTKNYKQS 87
 
Name Accession Description Interval E-value
Cript pfam10235
Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in ...
 11-97 5.76e-26

Microtubule-associated protein CRIPT; The CRIPT protein is a cytoskeletal protein involved in microtubule production. The C-terminal domain is essential for binding to the PDZ3 domain of the SAP90 protein, one of a super-family of PDZ-containing proteins that play an important role in coupling the membrane ion channels with their signalling partners. SAP90 is concentrated in the post synaptic density of glutamatergic neurons.


Pssm-ID: 431159  Cd Length: 87  Bit Score: 92.06  E-value: 5.76e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302687492  11 SQLAAPDPFKSSSSS--IKDGSRKVGENKLLSRPGssKNRFQPYQGKCKDCKSSVSQNKAKYCHGCAYKKGICAICGKQI 88
Cdd:pfam10235  1 TKLATPDPWKDGARNtlGESGGRKINENKLLSKKA--KNPYAAYSSKCKICKTKVHQPGAKYCQGCAYKKGICAMCGKKL 78


                 ....*....
gi 302687492  89 LDTTGYVMS 97
Cdd:pfam10235 79 LDTKNYKQS 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH