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Conserved domains on  [gi|302632637|ref|YP_003848733|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Tetranychus cinnabarinus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-295 1.94e-38

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 138.03  E-value: 1.94e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   1 MLNLLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNN--KEINIIYFIIQEMSSIMMIYMYMINNLFLLNF 78
Cdd:MTH00160   6 SKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLmsSESSLKYFLIQALASIILLFSIILNMLNLMLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  79 FILL----------KMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLNFIYMYMCNSW-SMMIILNLFMTTFSLFNAF 147
Cdd:MTH00160  86 NNISsmlinsslllKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFiIIIIILSAIIGAIGGLNQT 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 148 NNKYFYSIISLNSLSWIILLMFFNKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLNF-------KMLFFFVMLNMIS 220
Cdd:MTH00160 166 SLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSnnkskkiKFLLFLNLLSLGG 245

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302632637 221 FPPTIMFLMKIKIIFLLKMYNLtkFLLIFMIIIMLVFSMVFLMFFLNHFFVMEWLKEKINVKLNMIIYFNLMLMF 295
Cdd:MTH00160 246 LPPFLGFLPKWIIIQLLISNNM--FFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFL 318
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-295 1.94e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 138.03  E-value: 1.94e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   1 MLNLLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNN--KEINIIYFIIQEMSSIMMIYMYMINNLFLLNF 78
Cdd:MTH00160   6 SKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLmsSESSLKYFLIQALASIILLFSIILNMLNLMLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  79 FILL----------KMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLNFIYMYMCNSW-SMMIILNLFMTTFSLFNAF 147
Cdd:MTH00160  86 NNISsmlinsslllKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFiIIIIILSAIIGAIGGLNQT 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 148 NNKYFYSIISLNSLSWIILLMFFNKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLNF-------KMLFFFVMLNMIS 220
Cdd:MTH00160 166 SLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSnnkskkiKFLLFLNLLSLGG 245

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302632637 221 FPPTIMFLMKIKIIFLLKMYNLtkFLLIFMIIIMLVFSMVFLMFFLNHFFVMEWLKEKINVKLNMIIYFNLMLMF 295
Cdd:MTH00160 246 LPPFLGFLPKWIIIQLLISNNM--FFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFL 318
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-295 1.94e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 138.03  E-value: 1.94e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   1 MLNLLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNN--KEINIIYFIIQEMSSIMMIYMYMINNLFLLNF 78
Cdd:MTH00160   6 SKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLmsSESSLKYFLIQALASIILLFSIILNMLNLMLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  79 FILL----------KMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLNFIYMYMCNSW-SMMIILNLFMTTFSLFNAF 147
Cdd:MTH00160  86 NNISsmlinsslllKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFiIIIIILSAIIGAIGGLNQT 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 148 NNKYFYSIISLNSLSWIILLMFFNKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLNF-------KMLFFFVMLNMIS 220
Cdd:MTH00160 166 SLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSnnkskkiKFLLFLNLLSLGG 245

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302632637 221 FPPTIMFLMKIKIIFLLKMYNLtkFLLIFMIIIMLVFSMVFLMFFLNHFFVMEWLKEKINVKLNMIIYFNLMLMF 295
Cdd:MTH00160 246 LPPFLGFLPKWIIIQLLISNNM--FFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFL 318
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 11-296 2.15e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 83.00  E-value: 2.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  11 MFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNNKEINIIYFIIQEMSSIMMIymyMINNLFLLNFFILLKMGVPPMH 90
Cdd:MTH00091   1 LFLSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNYFVLQESLGLLFL---LFSFGYFQFLILMMKIGVAPFH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  91 NWLLKISIFLNWKILYMVMNFQKIIPLNFIYMYMCNSWSMMIILNLFMTTFSLFNAFNNKYFYSIISLNSLSWIILLMFF 170
Cdd:MTH00091  78 FWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMFLLKSYKNLLILSSTESFNWLILSFFF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 171 NKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLnfkmlfffVMLNMISFPPTIMFLMKIKIIFLLKMYNLTKFLLIFM 250
Cdd:MTH00091 158 SFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWE--------TLLVFMNLPFSVTFFVKIFSLSEILKVLGFFLLFLLF 229

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 302632637 251 IIIMLVFSMVFLMFFLNHFFVMEWLKekiNVKLNMIIYFNLMLMFL 296
Cdd:MTH00091 230 LMFLSVLSLSFWLVNLSTKLFLMLFK---YNKGFFFFFLPLMLLSL 272
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-295 4.35e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 53.35  E-value: 4.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   4 LLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLN--KLNNNKEINIIYFIIQEMSSIMMIY--------MYMINNL 73
Cdd:MTH00144   8 LFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVykKKSSESESVVKYFIIQSLGSSLLIFgslimynlSFSWFSM 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  74 FLLNFFILLKMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLNFIYMYMCNSWSMMIILNLFMTT-----FSLFNAFN 148
Cdd:MTH00144  88 SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLSalvgsIGGLNQTQ 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 149 NKYFYSIISLNSLSWIILLMFFNKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLNFKMLFFFVMLNMIS------FP 222
Cdd:MTH00144 168 VRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLllslggLP 247

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 302632637 223 PTIMFLMKIKIIFLlkmynLTKFLLIFMIIIMLVFSMVFLMFFLNHFFVMEWLKEKINVKLNMIIYFNLMLMF 295
Cdd:MTH00144 248 PFLGFCSKLLVLIS-----SMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISL 315
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 4-296 1.76e-06

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 48.52  E-value: 1.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   4 LLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNNKEIN--IIYFIIQEMSSIMMIYMYMINNLFLLNFFIL 81
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEgaMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  82 ---------LKMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLnFIYMYMCNSWSMMIILNLFMTTFSLFNAFNNKYF 152
Cdd:MTH00197  82 vvlvilgllLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL-LILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 153 YSII---SLNSLSWIILLMFFNKMFMLMYLLMYFYFNFFFLKNFSENNSKNFFNMLNF-------KMLFFFVMLNMISFP 222
Cdd:MTH00197 161 RQLLaysSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNpesmssnLVFLGLSFLSLGGLP 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 302632637 223 PTIMFLMKIKIIFLLKMYNltkfllIFMIIIMLVFSMVFLMFFLNHFFVMEWLKEKINVKLNMIIYFNLMLMFL 296
Cdd:MTH00197 241 PLSGFFLKWLILTSLLSSN------ISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFI 308
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-267 8.73e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 40.34  E-value: 8.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637   1 MLNLLLMYYFMFIFMVFLYSNMIMIWFYMEMSSMIFYIMLNKLNNNKEINII--YFIIQEMSSIMMI------------- 65
Cdd:MTH00200   5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATtkYFIIQATASALLLfggllnawtsgqw 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637  66 ---YMYMINNLFLLNFFILLKMGVPPMHNWLLKISIFLNWKILYMVMNFQKIIPLN-FIYMYMCNSWSMMIILNLFMTTF 141
Cdd:MTH00200  85 gisEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFAlLIQLAPALNSNILLLLGLLSVLV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302632637 142 SLFNAFNNKYFYSII---SLNSLSWIILLMFFNKMFMLMYLLMYF---YFNFFFLKNFSENNSKNFFNMLNF----KMLF 211
Cdd:MTH00200 165 GGWGGLNQTQLRKILaysSIAHLGWLLSGLVYSPNLALLYLLLYViitLTVFLLLNLLNSTKINSLSSSKTKnpilSMLL 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 302632637 212 FFVMLNMISFPPTIMFLMKikiifLLKMYNLTKFLLIFMIIIMLVFSMVFLMFFLN 267
Cdd:MTH00200 245 GLTLLSLGGLPPLTGFFPK-----WLILQELSKQGLFIYATILLLGSLLSLFFYLR 295
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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