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Conserved domains on  [gi|300669648|sp|Q8IZI9|]
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RecName: Full=Interferon lambda-3; Short=IFN-lambda-3; AltName: Full=Cytokine Zcyto22; AltName: Full=Interleukin-28B; Short=IL-28B; AltName: Full=Interleukin-28C; Short=IL-28C; Flags: Precursor

Protein Classification

IL28A domain-containing protein( domain architecture ID 10633532)

IL28A domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IL28A pfam15177
Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating ...
 34-192 1.90e-95

Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating the immune system. This protein family is induced by viral infection and interacts with a class II receptor. This family of proteins is found in eukaryotes. Proteins in this family are typically between 145 and 195 amino acids in length.


:

Pssm-ID: 464546  Cd Length: 157  Bit Score: 274.21  E-value: 1.90e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300669648   34 ARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATadTDP 113
Cdd:pfam15177   1 ARSCHISQFKSLSPRELEAFKKAKDALEESLLLKDRKCSSRLFPRKWDLRQLQVWERPVALEAELALTLKVLENM--TDS 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 300669648  114 ALGDVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASG 192
Cdd:pfam15177  79 ALADVLDQPLHTLRHIHSDLQACVEAQPTAGPRPSGRLRHWLHRLQEARKKESPGCLEASVTFNLFRLLTRDLKCVASG 157
 
Name Accession Description Interval E-value
IL28A pfam15177
Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating ...
 34-192 1.90e-95

Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating the immune system. This protein family is induced by viral infection and interacts with a class II receptor. This family of proteins is found in eukaryotes. Proteins in this family are typically between 145 and 195 amino acids in length.


Pssm-ID: 464546  Cd Length: 157  Bit Score: 274.21  E-value: 1.90e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300669648   34 ARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATadTDP 113
Cdd:pfam15177   1 ARSCHISQFKSLSPRELEAFKKAKDALEESLLLKDRKCSSRLFPRKWDLRQLQVWERPVALEAELALTLKVLENM--TDS 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 300669648  114 ALGDVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASG 192
Cdd:pfam15177  79 ALADVLDQPLHTLRHIHSDLQACVEAQPTAGPRPSGRLRHWLHRLQEARKKESPGCLEASVTFNLFRLLTRDLKCVASG 157
 
Name Accession Description Interval E-value
IL28A pfam15177
Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating ...
 34-192 1.90e-95

Interleukin-28A; The protein family, Interleukin-28A, plays an important role in modulating the immune system. This protein family is induced by viral infection and interacts with a class II receptor. This family of proteins is found in eukaryotes. Proteins in this family are typically between 145 and 195 amino acids in length.


Pssm-ID: 464546  Cd Length: 157  Bit Score: 274.21  E-value: 1.90e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300669648   34 ARGCHIAQFKSLSPQELQAFKRAKDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATadTDP 113
Cdd:pfam15177   1 ARSCHISQFKSLSPRELEAFKKAKDALEESLLLKDRKCSSRLFPRKWDLRQLQVWERPVALEAELALTLKVLENM--TDS 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 300669648  114 ALGDVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFRLLTRDLNCVASG 192
Cdd:pfam15177  79 ALADVLDQPLHTLRHIHSDLQACVEAQPTAGPRPSGRLRHWLHRLQEARKKESPGCLEASVTFNLFRLLTRDLKCVASG 157
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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