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Conserved domains on  [gi|299889191|dbj|BAJ10307|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Phoebastria immutabilis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-175 6.28e-55

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.08  E-value: 6.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYgMGLVLVVVVGGIVGGWGLVECWKLGVVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVV 160
Cdd:MTH00115  81 AWGDWGVVGY-VVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVV 159

                        170
                 ....*....|....*
gi 299889191 161 LELVRGLSCGAIRAV 175
Cdd:MTH00115 160 LELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-175 6.28e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.08  E-value: 6.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYgMGLVLVVVVGGIVGGWGLVECWKLGVVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVV 160
Cdd:MTH00115  81 AWGDWGVVGY-VVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVV 159

                        170
                 ....*....|....*
gi 299889191 161 LELVRGLSCGAIRAV 175
Cdd:MTH00115 160 LELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-163 1.80e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSL-AADPFPEAWGSWRVVGYGMGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299889191   96 LVVVVGGIVGGWGLVECWKLGVVTVDSGGMFSARLdfsgvamFYSCGAGMFLVAGWGLLLTLFVVLEL 163
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGEL-------LFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-175 6.28e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.08  E-value: 6.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYgMGLVLVVVVGGIVGGWGLVECWKLGVVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVV 160
Cdd:MTH00115  81 AWGDWGVVGY-VVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVV 159

                        170
                 ....*....|....*
gi 299889191 161 LELVRGLSCGAIRAV 175
Cdd:MTH00115 160 LELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-175 3.74e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 161.46  E-value: 3.74e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYGMGLVLVVVVGGIVGGWGLVE-CWklgVVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFV 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEgSW---VVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFV 157

                        170
                 ....*....|....*.
gi 299889191 160 VLELVRGLSCGAIRAV 175
Cdd:MTH00138 158 VLELTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-175 2.65e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 151.92  E-value: 2.65e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYGMGLVLVVVVGGIVGGWGLVecwKLGVVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVV 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFS---LEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVV 157

                        170
                 ....*....|....*
gi 299889191 161 LELVRGLSCGAIRAV 175
Cdd:MTH00065 158 LEVTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-166 2.35e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 103.34  E-value: 2.35e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVV------GYGMGLVLVVVVGGIVGGWGLVECWKLG-VVTVDSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGL 153
Cdd:MTH00109  82 TWVSNKVVlgalllGLLMELLLVLYVLKDDEVEVVFNFNGLGdWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 299889191 154 LLTLFVVLELVRG 166
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-175 1.62e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 90.82  E-value: 1.62e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   1 MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  81 AWGSWRVVGYGMGLVLVVVVGGIVGGWGLVECWKLGVVTVDSggmfsarLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVV 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANN-------LDLSGVSDLYSRGFFLLLLGGVVLFLVLFVV 153

                        170
                 ....*....|....*
gi 299889191 161 LELVRGLSCGAIRAV 175
Cdd:MTH00214 154 LELVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 10-174 6.97e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.70  E-value: 6.97e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  10 LCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGSWRVVG 89
Cdd:MTH00045   8 ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191  90 YGMGLVLVVVVGGIVGGWGLVecwklgvvtvdSGGMFSARLDFSGVAMFYSCGAGMFLVAGWGLLLTLFVVLELVRGLSC 169
Cdd:MTH00045  88 LSLLLSLWVFISFDNFLELSN-----------NNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEY 156


                 ....*
gi 299889191 170 GAIRA 174
Cdd:MTH00045 157 SSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-163 1.80e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299889191   17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSL-AADPFPEAWGSWRVVGYGMGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299889191   96 LVVVVGGIVGGWGLVECWKLGVVTVDSGGMFSARLdfsgvamFYSCGAGMFLVAGWGLLLTLFVVLEL 163
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGEL-------LFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 2.56e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 39.71  E-value: 2.56e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299889191   7 FLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 8.24e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.17  E-value: 8.24e-03
                         10        20
                 ....*....|....*....|....*.
gi 299889191  49 SFVSLVLFMVYLGGMLVVFVYSVSLA 74
Cdd:MTH00166  46 FWFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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