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Conserved domains on  [gi|298287852|gb|ADI73818|]
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NADH-ubiquinone oxidoreductase chain 4L [Methanohalobium evestigatum Z-7303]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-139 2.75e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


:

Pssm-ID: 237162  Cd Length: 140  Bit Score: 200.00  E-value: 2.75e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   1 MSNVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIIN-GHGSDSSSNIIFNDVLDNDV 79
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTKVPIITeQGHEGSGSGIIYNDNLTSGI 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852  80 LAPVVANTKEVVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRLWG 139
Cdd:PRK12661  81 LAPIVTNGPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
 
Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-139 2.75e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 200.00  E-value: 2.75e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   1 MSNVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIIN-GHGSDSSSNIIFNDVLDNDV 79
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTKVPIITeQGHEGSGSGIIYNDNLTSGI 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852  80 LAPVVANTKEVVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRLWG 139
Cdd:PRK12661  81 LAPIVTNGPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
3-137 1.16e-38

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 126.38  E-value: 1.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   3 NVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIINGHGSDSssniifndvldndvlap 82
Cdd:COG1006    2 ELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPILGEGPPAA----------------- 64

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 298287852  83 vvantkevVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRL 137
Cdd:COG1006   65 --------PYADPLPQALVLTAIVIGFAVTAFLLALAYRIYQLYGTDDVDELRED 111
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 4-131 5.92e-17

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 70.99  E-value: 5.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852    4 VFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIinghgsdsssniifndvldndvLAPV 83
Cdd:TIGR00941   3 SIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPI----------------------LTLP 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 298287852   84 VANtkevvYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDI 131
Cdd:TIGR00941  61 VGP-----YVDPLPQALILTAIVIGFATTALFLVVALRAYQVAGTDDV 103
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-137 2.05e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 61.43  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852    5 FLSLTIAILFGLGTFLIL-RKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPiinghgsdsssniifndvldndvlapv 83
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLP--------------------------- 53

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 298287852   84 vantkevvyvdplvQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRL 137
Cdd:pfam00420  54 --------------QALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLL 93
 
Name Accession Description Interval E-value
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-139 2.75e-67

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 200.00  E-value: 2.75e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   1 MSNVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIIN-GHGSDSSSNIIFNDVLDNDV 79
Cdd:PRK12661   1 MNNFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTKVPIITeQGHEGSGSGIIYNDNLTSGI 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852  80 LAPVVANTKEVVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRLWG 139
Cdd:PRK12661  81 LAPIVTNGPETEFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELRRLRG 140
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
3-137 1.16e-38

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 126.38  E-value: 1.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   3 NVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIINGHGSDSssniifndvldndvlap 82
Cdd:COG1006    2 ELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPILGEGPPAA----------------- 64

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 298287852  83 vvantkevVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRL 137
Cdd:COG1006   65 --------PYADPLPQALVLTAIVIGFAVTAFLLALAYRIYQLYGTDDVDELRED 111
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 4-135 1.12e-27

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 98.49  E-value: 1.12e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   4 VFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIINGHGSDsssniifndvldndvlapv 83
Cdd:PRK08600   3 ILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGAVPILGEGVTS------------------- 63

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 298287852  84 vantkevvYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELK 135
Cdd:PRK08600  64 --------YVDPLPQALILTAIVISFGVTAFFLVLAYRTYKELGTDNVEQMR 107
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
 6-128 1.37e-25

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 93.40  E-value: 1.37e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   6 LSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIINGHGSDSSSNiifndvldndvlapvva 85
Cdd:PRK09094   5 LALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMGRLRVGAPPVLQPGVPVDLAN----------------- 67

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 298287852  86 ntkevvYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGT 128
Cdd:PRK09094  68 ------YTDPLPQALVLTAIVIGFAMTALFLVVALASRGLTGT 104
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 3-135 9.67e-24

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 88.64  E-value: 9.67e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   3 NVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNA-PIINGHGSDsssniifndvldndvla 81
Cdd:PRK12660   2 NLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSePLITGGNQL----------------- 64

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 298287852  82 pvvantkevvYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELK 135
Cdd:PRK12660  65 ----------FVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLR 108
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
6-136 2.71e-23

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 87.81  E-value: 2.71e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   6 LSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIInGHGSDsssniifndvldndVLAPVVA 85
Cdd:PRK12658   5 FAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTREVPPLI-PAGAD--------------VLAEGAA 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 298287852  86 NtkevvyvdPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKR 136
Cdd:PRK12658  70 N--------PLPQALILTAIVIGFGLLAFLLVLAYRAYQDLGTDDTDEMRV 112
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
1-136 1.39e-21

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 83.01  E-value: 1.39e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   1 MSNVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIinghgsdsssniifndvldndvl 80
Cdd:PRK07375   1 MQLMIYALAIALLVIGLYGLIFKRNLLKKIIGLDVFQTGVNLFYIAIGYRSGGGVPI----------------------- 57

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 298287852  81 apvVANTKEVVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKR 136
Cdd:PRK07375  58 ---LSPSGFTTYADPLPQALVLTAIVIGFATTAVMLALIVKLYKDYGTLSESEIEK 110
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
4-135 4.02e-21

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 82.02  E-value: 4.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   4 VFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIInghgsdsssniifndvldndvlaPV 83
Cdd:PRK12659   3 FLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIFTVGRLTRGAPPLV-----------------------PE 59

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 298287852  84 VANTKEVVYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELK 135
Cdd:PRK12659  60 GATAPAGPVADPLPQALILTAIVIGFGVQAFAIVLIKRAYQVVGTDDLDEMK 111
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-130 2.21e-18

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 76.24  E-value: 2.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   1 MSNVFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGdNAPIINGHGSDSSSniifndvldndvl 80
Cdd:PRK07946   2 TANLGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGGPAG-NPPILGRTSEYGET------------- 67

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 298287852  81 apvVAntkevvyvDPLVQALVLTAIVIGFSITAFILILAYRIYeEYGTTD 130
Cdd:PRK07946  68 ---MA--------DPLAQAMILTAIVITMGITAFVLALAYRSY-RLTTAD 105
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 4-131 5.92e-17

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 70.99  E-value: 5.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852    4 VFLSLTIAILFGLGTFLILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIinghgsdsssniifndvldndvLAPV 83
Cdd:TIGR00941   3 SIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPI----------------------LTLP 60

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 298287852   84 VANtkevvYVDPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDI 131
Cdd:TIGR00941  61 VGP-----YVDPLPQALILTAIVIGFATTALFLVVALRAYQVAGTDDV 103
PRK08389 PRK08389
putative monovalent cation/H+ antiporter subunit C; Reviewed
 20-139 1.21e-15

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236258  Cd Length: 114  Bit Score: 67.84  E-value: 1.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852  20 LILRKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPIINGHGSDSSsniifndvldndvlapvvantkevvYVDPLVQA 99
Cdd:PRK08389  20 VLVKKNLLKIIIGLDIMETGVNLLLISIGYVSGRSAPILSEGITPSN-------------------------YVDPIPQA 74

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 298287852 100 LVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRLWG 139
Cdd:PRK08389  75 LVLTAIVIGVSTTALALSVAIKLYEKYGTLNVEEIRRLRG 114
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-137 2.05e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 61.43  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852    5 FLSLTIAILFGLGTFLIL-RKDVIKVIIGLSIISHAVNVFIVSSGVFNGDNAPiinghgsdsssniifndvldndvlapv 83
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLP--------------------------- 53

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 298287852   84 vantkevvyvdplvQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRL 137
Cdd:pfam00420  54 --------------QALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLL 93
PRK08388 PRK08388
putative monovalent cation/H+ antiporter subunit C; Reviewed
 5-139 2.15e-10

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236257  Cd Length: 119  Bit Score: 54.52  E-value: 2.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 298287852   5 FLSLTIAILFGLGTFLiLRKDVIKVIIGLSIISHAVNVFIVSSG--VFNGD--NAPIINGHGSDSSsniifndvldndvl 80
Cdd:PRK08388   6 FITAFLMIALGIYAFL-YKRNLIKLILALDLIDSGIHLLLISLGyrMENGLppTAPIYTGYETLKS-------------- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 298287852  81 aPVVAntkevvyvdPLVQALVLTAIVIGFSITAFILILAYRIYEEYGTTDITELKRLWG 139
Cdd:PRK08388  71 -PMVG---------PIPQALVLTSIVIGVCVLSLAMALTINAYRHYGTLDVTKLRRLRG 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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