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Conserved domains on  [gi|29789409|ref|NP_777549|]
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NDUFA12 super family cl47913
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 23-90 7.26e-13

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


The actual alignment was detected with superfamily member pfam05071:

Pssm-ID: 461542  Cd Length: 96  Bit Score: 61.07  E-value: 7.26e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 29789409    23 VGTDQFGNKYYyipqyKNWRGQTIREKRIVEAANKkevDYEAGDIPTEWEAWIRRTRKTPPTMEEILK 90
Cdd:pfam05071   3 VGEDEFGNKYY-----ENKDEELPGRRRWVIYNDG---DYDASQVPPEWHGWLHYITDDPPTEDPILQ 62
 
Name Accession Description Interval E-value
NDUFA12 pfam05071
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 23-90 7.26e-13

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


Pssm-ID: 461542  Cd Length: 96  Bit Score: 61.07  E-value: 7.26e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 29789409    23 VGTDQFGNKYYyipqyKNWRGQTIREKRIVEAANKkevDYEAGDIPTEWEAWIRRTRKTPPTMEEILK 90
Cdd:pfam05071   3 VGEDEFGNKYY-----ENKDEELPGRRRWVIYNDG---DYDASQVPPEWHGWLHYITDDPPTEDPILQ 62
PLN03095 PLN03095
NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional
 23-87 1.69e-07

NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional


Pssm-ID: 215571  Cd Length: 115  Bit Score: 47.57  E-value: 1.69e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29789409   23 VGTDQFGNKYYYIPQYKNWRgqtireKRIVEAANKKevDYEAGDIPTEWEAWIRRTRKTPPTMEE 87
Cdd:PLN03095  13 VGEDEFGNKYYENPSYQSGR------HRWVEYADKD--DYNASNIPPEWHGWLHYVNDEPGELED 69
 
Name Accession Description Interval E-value
NDUFA12 pfam05071
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 23-90 7.26e-13

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


Pssm-ID: 461542  Cd Length: 96  Bit Score: 61.07  E-value: 7.26e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 29789409    23 VGTDQFGNKYYyipqyKNWRGQTIREKRIVEAANKkevDYEAGDIPTEWEAWIRRTRKTPPTMEEILK 90
Cdd:pfam05071   3 VGEDEFGNKYY-----ENKDEELPGRRRWVIYNDG---DYDASQVPPEWHGWLHYITDDPPTEDPILQ 62
PLN03095 PLN03095
NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional
 23-87 1.69e-07

NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional


Pssm-ID: 215571  Cd Length: 115  Bit Score: 47.57  E-value: 1.69e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29789409   23 VGTDQFGNKYYYIPQYKNWRgqtireKRIVEAANKKevDYEAGDIPTEWEAWIRRTRKTPPTMEE 87
Cdd:PLN03095  13 VGEDEFGNKYYENPSYQSGR------HRWVEYADKD--DYNASNIPPEWHGWLHYVNDEPGELED 69
PRK08183 PRK08183
NADH:ubiquinone oxidoreductase subunit NDUFA12;
21-96 4.15e-07

NADH:ubiquinone oxidoreductase subunit NDUFA12;


Pssm-ID: 236176 [Multi-domain]  Cd Length: 133  Bit Score: 46.52  E-value: 4.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789409   21 EHVGTDQFGNKYYyipQYKNWRGQTIREKRIV----EAankkevdyEAGDIPTEWEAWIRRTRKTPPTMEeilkNEKHRE 96
Cdd:PRK08183  27 ERVGEDEFGNVYY---RTKGGKPSDGRERRWViyngYA--------EASRIPPEWHGWLHHTVDVPPTKE----PYPPRE 91
PLN02732 PLN02732
Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit
 23-122 2.51e-03

Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit


Pssm-ID: 215389  Cd Length: 159  Bit Score: 36.44  E-value: 2.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789409   23 VGTDQFGNKYyyipqYKNWRGQTIREKRIVEAANKKEvdYEAGDIPTEWEAWIRRTrkTPPTMEEILKNEKHREEIKIKS 102
Cdd:PLN02732  52 VGVDKFGNKY-----YQKLGDTQYGRHRWVEYAEKSR--YNASQVPAEWHGWLHFI--TDHTGDELLMLKPKRYGLEHKE 122

                         90       100
                 ....*....|....*....|
gi 29789409  103 QDFYEKEKLLSKETSEELLP 122
Cdd:PLN02732 123 NFSGEGEEYIYHSKGHTLNP 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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